Virus that infects and replicates within bacteria
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40 episodes with bacteriophages
62 episodes with bacteriophages
16 episodes with bacteriophages
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5 episodes with bacteriophages
5 episodes with bacteriophages
5 episodes with bacteriophages
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TWiV reviews universal vaccine initiative at NIAID, shut down of the Integrated Research Facility at Ft. Detrick, modeling the reemergence of infectious diseases as vaccination rates drop, and bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection. Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Paul has Measles (YouTube, virology blog) Universal vaccine project (NIAID, CIDRAP) Measles update (US, Texas) Integrated Research Lab closed (Telegraph) Modeling reemergence of infectious diseases (JAMA) Outer membrane vesicles attached to phage (Front Cell Inf Micro) Pf phage review (Front Immunol) Letters read on TWiV 1215 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Alan – A Paradise Built in Hell, by Rebecca Solnit (and here's my review of it) Jolene – Virology course student communication projects, Spring 2025 Vincent – Vaccine Education Center Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode of Going anti-Viral, Dr Michael Saag speaks with Dr Graham Hatfull, a Professor of Biological Sciences at the University of Pittsburgh. Dr Hatfull joins Dr Saag to discuss Bacteriophages for the treatment of antimicrobial-resistant (AMR) bacterial infections. Dr Hatfull provides an overview of the types of bacteriophages and how they can be used to treat antimicrobial-resistant bacteria. Dr Hatfull and Dr Saag discuss the challenges of treating bacterial infections with phages given the diversity and complexity of the different types of bacteria and bringing phage treatments to scale. Finally, they discuss what research is needed to overcome the challenges of phage treatment and look to the future where technology enables synthetically produced phages to provide targeted therapy to antimicrobial resistant bacteria.0:00 – Introduction1:05 – Overview of bacteriophages and Dr Hatfull's interest in phage research2:46 – How phages can be used clinically for antimicrobial-resistant bacteria4:34 – Differences between the 2 types of phages: lytic phages and temperate phages6:01 – How phages are used to target specific types of bacteria9:37 – The challenge of phage treatment matching and natural CRISPR processes within bacteria15:16 – Understanding the phage genome diversity 18:59 – Discussion of therapeutic uses of phages28:32 – Prospect of phages for future treatments including synthetic phagesResources: Harnessing the Power of Bacteriophages with Dr Robert Schooley:YouTube: https://youtu.be/_BUpDRNhMsQApple Podcasts: https://podcasts.apple.com/us/podcast/episode-10-harnessing-the-power-of-bacteriophages/id1713226144?i=1000647215580 Exploring Bacteriophage Therapy for Drug-Resistant Bacterial Infections Robert T. Schooley, MD: https://www.iasusa.org/wp-content/uploads/2023/03/31-1-23.pdf The inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics: https://www.iasusa.org/bacteriophage-conference/ __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
Send us a textDr. Jessica Sacher, Ph.D. is Co-Founder of Phage Directory ( https://phage.directory/ ), a global network of phage researchers from more than 80 countries, where she directs its phage-sourcing and community-building efforts, including coordinating over 50 phage-finding efforts, where a network of more than 1,300 members of the global phage community volunteer their time and lab space to identify active phages for patients.Dr. Sacher is also a Staff Scientist at Stanford University School of Medicine ( https://profiles.stanford.edu/jessica-sacher ) in Dr. Paul Bollyky's lab where she leads strategy & lays groundwork for a new phage-based therapeutic development and delivery center at Stanford, developing manufacturing processes and quality control pipelines for clinical-grade phage biologics, as well as evaluating phages as gene and peptide delivery vectors for eukaryotic and microbial cells.Dr. Sacher was previously a member of Prof. Jon Iredell's group in Sydney, Australia as a postdoctoral research scientist for the Phage Australia project where she developed and streamlined Phage Australia's phage selection, biobanking, and manufacturing process, to make phage therapy available for patients Australia-wide and eventually beyond.Dr. Sacher received her PhD in Microbiology and Biotechnology in 2018 from the University of Alberta, Canada.Dr. Sacher is also Founder, Editor, Writer of Capsid & Tail: the phage community newsletter, a weekly report on bacteriophage news and researchImportant Episode Links - Bacteriophage therapy for multidrug-resistant infections: current technologies and therapeutic approaches - Published March 3, 2025 - The Journal of Clinical Investigation -https://www.jci.org/articles/view/187996The Citizen Phage Library (https://citizenphage.com) #JessicaSacher #PhageDirectory #Bacteriophage #StanfordUniversity #Campylobacter #SteffanieStrathdee #Microbiology #PhageBiobank #Biofilms #AMR #AntimicrobialResistance #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show
The entire TWiV team comes together to pay tribute to Dickson Despommier, then reviews antibodies to H5N1 virus in veterinarians working with dairy cattle, Elisabeth Bik donates prize money for data integrity analyses, measles outbreak in Texas, and use of an alternative genetic code by human microbiome phages. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, Daniel Griffin, Angela Mingarelli, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Livestream tribute to Dickson (Office Hours) Dickson's Wikipedia page Dickson's obituary (NY Times) Dickson websites: trichinella.org, thelivingriver.org, fordhamopolis.com, despommierphotoart.com Alan's tribute to Dickson (alandove.com) H5N1 seroprevalence (MMWR) Elisabeth Bik donates prize money (Science) Measles outbreak in Texas (Texas DSHS) Human microbiome phages use alternative genetic code (Nat Comm) Letters (mostly not) read on TWiV 1195 – all about Dickson Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Rare spotting of humpback anglerfish “diablo negro” (Melanocetus johnsonii) in Tenerife, Canary Islands. First time ever observed alive! Brianne – Moonwalking with Einstein inspired by reading NY Times article about Recent memory champ Kathy – Witness History 9 minute podcasts Rich – APOD: Perijove 11: Passing Jupiter Alan – Ecological succession on abandoned farmland Jolene – Parasitic Diseases Lectures and first 27 episodes of This Week in Parasitism Vincent – The New City Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode of Tiny Show and Tell Us, we consider if bacteriophages could become our biggest allies in the fight against antibiotic resistance. Then we cover the historical role of "night soil men" and how some sewage treatment systems today are setting the standard for sustainable management of human excrement while also making sure we don't get sick. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.
If you're in the field of bacteriophage therapy or looking to break into the space, you won't want to miss the 7th Bacteriophage Therapy Summit happening next month in Boston!
Matters Microbial #73: Seeing the Microbiome January 8, 2025 Today, Dr. Travis Wiles, Assistant Professor of Molecular Biology and Biochemistry at the University of California, Irvine, joins the #QualityQuorum to discuss the work he and his research group have done to visualize the changing dynamics of the gut microbiome—including bacteriophages residing there. Host: Mark O. Martin Guest: Travis Wiles Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Dr Anne Estes' academic website is found here, along with her blog, and her social media link on Bluesky. So many interesting ideas! Transgenic zebrafish as pets are called GLOfish. Use of zebrafish as a model system for developmental biology. An article exploring the effects of the microbiome on gnotobiotic (“germ free”) zebrafish. An essay on both lytic and lysogenic bacteriophages. An essay describing how bacteriophage interact with the gut microbiota. One of my former undergraduate research students, Dr. Danielle Campbell, works in this area! An article suggesting that bacteriophage do in fact interact with eukaryotic cells. The concept of phage conversion: how some bacteriophages carry bacterial genes, including toxin genes. An article about bacteriophages and bacterial evolution. An article about the study of the zebrafish gut microbiome. An article about research with zebrafish and Mycobacterium. The article discussed in this episode by Dr. Wiles' group: “Phollow: Visualizing Gut Bacteriophage Transmission within Microbial Communities and Living Animals .” Dr. Wiles' academic website. Dr. Wiles' very colorful and interesting laboratory group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bhattacharya nominated to head NIH (Science) Makary nominated to head FDA (Science) Weldon nominated to head CDC (Chief Healthcare Exec) Cervical cancer declining following vaccination (JAMA Net) Local dengue case in Texas (Texas HHS) H5N1 human isolate transmissible and virulent (Nature) H5 current situation (CDC) Global H5N1 cases (Our World in Data) Conserved immune evasion in animal and bacterial viruses (Cell) Timestamps by Jolene. Thanks! Weekly Picks Brianne – Pale Blue Pod Kathy – PhysicsGirl recent Instagram post, ScienceAdvisor signup free daily sci news distillation, Semi-conducting hydrogels, Bot that can pick up things with a soft touch, “Pigeonbot II”, a drone called LisRaptor, zapping forever chemicals like PFAS with light and here Rich – Vendee Globe Jolene – Center for the Improvement of Mentored Research Experiences Vincent – These two ancient human relatives crossed paths 1.5 million years ago Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
It sounds like something from an advertisement for bathroom cleaner: Researchers found over 600 different viruses, most of which are new to science, in samples taken from showerheads and toothbrushes. The viruses, however, are unlikely to affect humans. They are bacteriophages, a type of virus that preys on bacteria. The expedition into bathroom biodiversity was recently published in the journal Frontiers in Microbiomes.Around a hundred years ago in the former Soviet Union, there were major efforts to develop bacteriophages for medical use. The approach really didn't catch on in Western countries, overshadowed there by the rise of conventional antibiotics like penicillin. But with some diseases developing resistance to those conventional antibiotics, there's been increased interest in phages as part of an antibacterial toolkit.Dr. Erica Hartmann, an associate professor in the department of Civil & Environmental Engineering at Northwestern University, joins Ira to talk about what researchers found when they took a close look at a collection of bathroom samples, and how phage research has advanced in recent years.Transcript for this segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Bacteriophage technology is being used to address acne, eczema, and other dysbiotic skin concerns. Some microbiology companies are working with endolysins (proteins produced by phages), others are focused on formulating skincare with phages themselves. This week on the CosmoFactory podcast, we consider possible cosmetic industry applications for bacteriophage technology. Our guest is Milan Bunata, Business Director of FagoFarma, a biotech company specialized in phage-based preparations for use in the cosmetics, pharma, and veterinary industries. Based in the Czech Republic, FagoFarma was established in 2013. And this year, in an effort to both educate consumers about phage-based skincare and to gather feedback, the company launched a consumer acne care product called FagoCare Gel. If you appreciate this episode, SHARE it with a colleague, SUBSCRIBE to the CosmoFactory podcast & please LEAVE US A REVIEW today. With your help, even more cosmetic industry professionals can discover the inspiring interviews we share on CosmoFactory! ABOUT CosmoFactoryBeauty industry stakeholders listen to the CosmoFactory podcast for inspiration and for up-to-date information on concepts, tactics, and solutions that move business forward. CosmoFactory – Ideas to Innovation is a weekly interview series for cosmetics and personal care suppliers, finished product brand leaders, retailers, buyers, importers, and distributors. Each Tuesday, CosmoFactory guests share experiences, insights, and exclusive behind-the-scenes details—which makes this not only a must-listen B2B podcast but an ongoing case study of our dynamic industry. Guests are actively working in hands-on innovation roles along the beauty industry supply chain; they specialize in raw materials, ingredients, manufacturing, packaging, and more. They are designers, R&D or R&I pros, technical experts, product developers, key decision makers, visionary executives. HOST Deanna UtroskeCosmetics and personal care industry observer Deanna Utroske hosts the CosmoFactory podcast. She brings an editorial perspective and a decade of industry expertise to every interview. Deanna is also Editor of the Beauty Insights newsletter and a supply-side positioning consultant. She writes the Global Perspectives column for EuroCosmetics magazine, is a former Editor of CosmeticsDesign, and is known globally for her ability to identify emerging trends, novel technologies, and true innovation in beauty. A PRODUCTION OF Cosmoprof Worldwide BolognaCosmoFactory is the first podcast from Cosmoprof Worldwide Bologna, taking its place among the best B2B podcasts serving the global beauty industry. Cosmoprof Worldwide Bologna is the most important beauty trade show in the world. Dedicated to all sectors of the industry, Cosmoprof Worldwide Bologna welcomes over 250,000 visitors from 150 countries and regions and nearly 3,000 exhibitors to Bologna, Italy, each year. It's where our diverse and international industry comes together to build business relationships and to discover the best brands and newest innovations across consumer beauty, professional beauty, and the entire supply chain. The trade show includes a robust program of exclusive educational content, featuring executives and key opinion leaders from every sector of the cosmetics, fragrance, and personal care industry. Cosmoprof Worldwide Bologna is the most important event of the Cosmoprof international network, with exhibitions in Asia (Hong Kong), the US (Las Vegas and Miami), India (Mumbai) and Thailand (Bangkok). Thanks to its global exhibitions Cosmoprof connects a community of more than 500,000 beauty stakeholders and 10,000 companies from 190 countries and regions. Learn more today at Cosmoprof.com
Matters Microbial #62: Should I Stay, or Should I Go—How Bacteriophage are Released from Host Cells October 23, 2024 Today, Dr. Jolene Ramsey, of the Biology Department of Texas A&M University and Affiliate of the Center for Phage Technology, joins the #QualityQuorum to discuss how bacteriophages release themselves from host cells, her efforts to teach students to work with the primary literature, and her own path to the microbial sciences. Host: Mark O. Martin Guest: Jolene Ramsey Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A truly wonderful reminder video about bacteriophages. A link with a 3D printer design of capsid model pieces (personally, I am really interested in making one of these!). A video demonstrating how the capsid model pieces self assemble—something like real viruses can? An essential book about bacteriophage authored by my late friend Merry Youle. A fine book describing how bacteriophages can be used to fight bacterial diseases. This “first person” book by #MattersMicrobial podcast guest Steffanie Strathdee about how she was able to use bacteriophages to save her husband's life is a must read. A link to the Citizen's Phage Library. A link to the truly fabulous (yes, I am jealous I am not part of this program) CURE program SEA-PHAGES and SEA-GENES for undergraduate students. A remarkable illustration of T4 bacteriophage bursting from host cells by the scientist-artist David Goodsell. The organization that designed Dr. Ramsey's laboratory logo. A link to the Clinical Genome Curation for Human Genes. A link to the CACAO website for biocuration competition. A recent Ramsey lab mini-review on phage classification. A link to the Center for Phage Technology. The Ramsey lab Instagram page. The Ramsey lab YouTube channel. Dr. Ramsey's laboratory website. Dr. Ramsey's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
This summer, I participated in a human challenge trial at the University of Maryland. I spent the days just prior to my 30th birthday sick with shigellosis. What? Why?Dysentery is an acute disease in which pathogens attack the intestine. It is most often caused by the bacteria Shigella. It spreads via the fecal-oral route. It requires an astonishingly low number of pathogens to make a person sick – so it spreads quickly, especially in bad hygienic conditions or anywhere water can get tainted with feces.It kills about 70,000 people a year, 30,000 of whom are children under the age of 5. Almost all of these cases and deaths are among very poor people.The primary mechanism by which dysentery kills people is dehydration. The person loses fluids to diarrhea and for whatever reason (lack of knowledge, energy, water, etc) cannot regain them sufficiently. Shigella bacteria are increasingly [...] ---Outline:(00:15) What? Why?(01:18) The deal with human challenge trials(02:46) Dysentery: it's a modern disease(04:27) Getting ready(07:25) Two days until challenge(10:19) One day before challenge: the age of phage(11:08) Bacteriophage therapy: sending a cat after mice(14:14) Do they work?(16:17) Day 1 of challenge(17:09) The waiting game(18:20) Let's learn about Shigella pathogenesis(23:34) Let's really learn about Shigella pathogenesis(27:03) Out the other side(29:24) AftermathThe original text contained 3 footnotes which were omitted from this narration. The original text contained 2 images which were described by AI. --- First published: October 22nd, 2024 Source: https://www.lesswrong.com/posts/inHiHHGs6YqtvyeKp/i-got-dysentery-so-you-don-t-have-to --- Narrated by TYPE III AUDIO. ---Images from the article:
From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections. Hosts: Vincent Racaniello and Jolene Ramsey Guests: Krystyna Dabrowska and Rob Lavigne Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Viruses of Microbes 2024 Immune responses to phages (Front Immunol) Engineering bacteriolytic enzymes (Front Immunol) 100 cases of phage therapy (Nat Micro) Synthetic biology potential of bacteriophages (Nat Micro) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Today, Dr. Cynthia Silveira of the Department of Biology at Miami University joins the #QualityQuorum to discuss her research team's efforts to explore how bacterial viruses interact with their host cells from coral reefs to other planets! In addition, Dr. Silveira will discuss her microbiological path and a course she teaches on virology. Host: Mark O. Martin Guest: Cynthia Silveira Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video about marine bacteriophages and the role they play in ecological systems. A fine article about the role that bacteriophages can have in marine environments. An essay suggested that marine viruses may influence global climate. A link to the wonderful book, “Coral Reefs in a Microbial Sea.” Forest Rohwer's laboratory website. The role of a retrovirus in the development of the mammalian placenta. A bacterial role in snow making, using the commercial product “Snomax.” A “faculty spotlight” essay on Dr. Silveiro. Dr. Silveiro's laboratory website. Dr. Silveiro's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
TWiV reviews polio vaccination campaign in Gaza, viruses with zoonotic potential in farmed fur animals, low HPV vaccination in North Texas associated with high rates of cervical cancer, a large flavivirus genome that does not encode error correction machinery, and antiphage defense through inhibition of virion assembly. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Polio vaccination in Gaza (Reuters) Zoonotic viruses in farmed fur animals (Nature) HPV vaccination and cancer rates (JAMA Net Open) 40 kb RNA genome without error correction (PNAS) Stopping the phage tape measure protein (Nat Commun) Tail assembly interference (Nat Commun) Letters read on TWiV 1151 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Digital nature pics winners 2024 Wildlife Photographer of the Year Alan – Adorable story about a Nigerian paralympian couple who are both polio survivors Jolene – Capsid assembly model with self-assembling pentamers in 3D print model (plus three more models now available if search self assembling virus) and Wonderlab article about exhibit using this to teach about viral patterns in Bloomington Indiana Science museum Vincent – The collapse of bat populations led to more than a thousand infant deaths Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode, we dive into the incredible role of T4D-Myoviridae bacteriophages in targeting Escherichia coli strains, highlighting their unique contractile tail structures that facilitate precise DNA injection into host cells. We explore the specific interactions between phage tail fibers and bacterial lipopolysaccharide receptors, illustrating the phage's lock-and-key mechanism crucial for selective bacterial lysis. This discussion extends into the implications for combatting SIBO and enhancing gut microbiota balance while exploring the impressive scientific literature on phage-mediated modulation of gut flora and inflammatory markers. Topics: 1. Introduction to Bacteriophages - Explanation of what a bacteriophage (phage) is. - Importance of phages in research and their role in intestinal dysbiosis. 2. Bacteriophage Foundation - Description of bacteriophage structure: - Capsid and its genetic material (DNA or RNA). - Icosahedral head and its efficiency. - Types of phage tails and their functions: - Contractile tails: mechanism similar to a syringe. - Non-contractile tails: static structure for attachment. 3. Phage-Bacteria Interaction - Initial attachment to bacterial cell via tail fibers. - Specificity of attachment (lock and key mechanism). - Injection of genetic material into the bacterial cell. - Use of bacterial machinery to replicate phage components. 4. Phage Replication Cycle - Overview of the phage replication process within the host cell: - Integration and takeover of host cellular machinery. - Assembly of new phage particles. - Release of phages through lysis of the host cell. 5. Application - Potential of phages to selectively target and kill bacteria. - Benefits over broad-spectrum targeting. - Discussion of antibiotic resistance. 6. Diving into the Gut Microbiome - Connection between phages and the gut microbiome. - Discussion of specific phages like T4D-Myoviridae and their targets. - Relevance to SIBO (Small Intestinal Bacterial Overgrowth). 7. Case Studies and Research - Review of studies on phage impact on gut microbiota and inflammation. - Specific changes in microbiota observed in research (e.g., increase in butyrate-producing genera). Thank you to our episode sponsor: Liver Medic Use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
Melvyn Bragg and guests discuss the most abundant lifeform on Earth: the viruses that 'eat' bacteria. Early in the 20th century, scientists noticed that something in their Petri dishes was making bacteria disappear and they called these bacteriophages, things that eat bacteria. From studying these phages, it soon became clear that they offered countless real or potential benefits for understanding our world, from the tracking of diseases to helping unlock the secrets of DNA to treatments for long term bacterial infections. With further research, they could be an answer to the growing problem of antibiotic resistance.With Martha Clokie Director for the Centre for Phage Research and Professor of Microbiology at the University of LeicesterJames Ebdon Professor of Environmental Microbiology at the University of BrightonAnd Claas Kirchhelle Historian and Chargé de Recherche at the French National Institute of Health and Medical Research's CERMES3 Unit in Paris.Producer: Simon TillotsonIn Our Time is a BBC Studios Audio ProductionReading list: James Ebdon, ‘Tackling sources of contamination in water: The age of phage' (Microbiologist, Society for Applied Microbiology, Vol 20.1, 2022) Thomas Häusler, Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? (Palgrave Macmillan, 2006)Tom Ireland, The Good Virus: The Untold Story of Phages: The Mysterious Microbes that Rule Our World, Shape Our Health and Can Save Our Future (Hodder Press, 2024)Claas Kirchhelle and Charlotte Kirchhelle, ‘Northern Normal–Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939-2000)' (SocArXiv Papers, 2024) Dmitriy Myelnikov, ‘An alternative cure: the adoption and survival of bacteriophage therapy in the USSR, 1922–1955' (Journal of the History of Medicine and Allied Sciences 73, no. 4, 2018)Forest Rohwer, Merry Youle, Heather Maughan and Nao Hisakawa, Life in our Phage World: A Centennial Field Guide to Earth's most Diverse Inhabitants (Wholon, 2014)Steffanie Strathdee and Thomas Patterson (2019) The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir (Hachette Books, 2020)William C. Summers, Félix d`Herelle and the Origins of Molecular Biology (Yale University Press, 1999)William C. Summers, The American Phage Group: Founders of Molecular Biology (University Press, 2023)
Origem e Evolução dos Vírus https://chatgpt.com/share/1550f9b3-7869-489f-8593-956aafec53cc Bacteriophages https://www.bbc.co.uk/sounds/play/m0020pf0 (via ChatGPT) Viruses: Earth's Most Abundant https://chatgpt.com/share/e16433aa-03ce-49a5-9b24-d121859a0195 Stupidity: A powerful force in human history https://youtu.be/zvjcJsy51oc?si=i0si0DNLVV7-2Hyp (via Perplexity AI) why did the assassination of archduke Franz Ferdinand cause the first world war? https://www.perplexity.ai/search/why-did-the-assassination-of-a-f_PZHBC6QL..vaMl4J3wbQ Como ‘anistiaço' do MP e governo de MT livrou fazendeiros de pagar indenizações por desmatamento ... Read more The post a sabedoria sustentável de Edo no Japão, flores x níquel, Hiérocles e a empatia universal appeared first on radinho de pilha.
Hello there!In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Dianna Bourassa continues her discussion on innovative methods to improve food safety in poultry production. Dr. Bourassa explores the use of bacteriophages to reduce salmonella in chickens, touching on their characterization, application, and economic challenges. Additionally, she discusses future advancements and the potential of high-intensity light flashing as an antimicrobial method. Don't miss this insightful episode, available on all major platforms."There are already bacteriophage products on the market against salmonella, but they aren't economically viable yet." - Dr. Dianna BourassaMeet the guest: Dr. Dianna Bourassa, an Associate Professor at Auburn University, specializes in poultry processing and food safety. With a rich background in microbiology from the University of Georgia, Dr. Bourassa has dedicated her career to advancing poultry health through innovative research. Her work, especially on bacteriophages against Salmonella, is pivotal for the poultry industry, offering new avenues for enhancing food safety and processing techniques. What you'll learn:(00:00) Highlight(01:26) Introduction(01:53) Characterizing bacteriophages(02:26) Reducing salmonella with bacteriophages(03:53) Pre-harvest application of bacteriophages(04:45) Market availability and cost challenges(06:29) High-intensity light flashing(09:32) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kerry* Cargill- Anitox- Kemin- BASF
A war has been raging for billions of years, killing trillions every single day, while we don't even notice. This war involves the single deadliest being on our planet: The Bacteriophage. Follow the show to join us in this audio experience of Kurzgesagt - In a Nutshell. A fan-made show out of admiration for the works of Kurzgesagt - In a Nutshell. Learn more about your ad choices. Visit megaphone.fm/adchoices
TWiV discusses effectiveness of this season's flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Effectiveness of flu vaccine (MMWR, Eurosurveill) Efficacy of Pfizer RSV vaccine (Pfizer) Understanding six types of vaccine technologies (Pfizer) nOPV in US? (CDC) Dengue in Peru (Peruvian State) Measles in Michigan and Indiana Marburg virus control by reservoir bats (Nat Commun) tRNA acquisition by phages (Cell) Viruses of Microbes 2024 Timestamps by Jolene. Thanks! Weekly Picks Brianne – The reappearance of Lake Manly Kathy – “Practical Playbook for Addressing Health Misinformation” Rich – Making It So: A Memoir by Patrick Stewart Jolene – Thinking Like a Phage by Merry Youle Vincent – The Science of Leap Year Listener Picks Blog design – Anthony Fauci will reflect on his long government career in ‘On Call,' to be published in June Peter – Republican warns of vaccines being slipped into vegetables: ‘A polio vaccine in there' Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
Episode 10 - Harnessing the Power of Bacteriophages With Dr Robert SchooleyIn this podcast episode, host Dr Michael Saag speaks with Dr Robert “Chip” Schooley, a distinguished Professor of Medicine in the Division of Infectious Diseases and Global Public Health at the University of California San Diego. They discuss the revolutionary potential of bacteriophages, viruses that can infect and kill bacteria. They detail the research efforts and case studies involved in understanding the potential deployment of bacteriophages as a medical treatment. The discussion also highlights the necessity for clinical trials and future research involving genetically engineered phages.00:02 Introduction and Guest Profile01:51 The Growing Problem of Antimicrobial Resistance02:55 Understanding Bacteriophages04:21 The History and Use of Bacteriophages in Labs05:45 The Role of Bacteriophages in Molecular Biology11:43 The Journey of Treating a Patient with Bacteriophages19:19 The Future of Bacteriophage Therapy31:05 Closing Remarks and Podcast Outro__________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTube InstagramTikTok...
Dr. Diaz Vera, Infectious Diseases Fellow at the University of South Florida Division of Infectious Diseases, presents a companion lecture to his original talk on bacteriophage therapy. Because of the rising tide of antimicrobial resistance, many experts believe that we are entering the post-antibiotic era in medicine. As a result, researchers are exploring phage-antimicrobial synergy in an attempt to make our antibiotic armamentarium go farther. Dr. Diaz elaborates on the application of phage-antimicrobial synergy and provides examples of phage therapy utilized in the clinical setting. For Dr. Diaz’s original talk, please click here: Intro to Bacteriophage therapy
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/southeast-asian-studies
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/food
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia.
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/australian-and-new-zealand-studies
Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world's protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices
Vincent travels to McGill University in Montreal, Canada to join Angela for a discussion of the careers and the research of two faculty members, Corinne Maurice and Jesse Shapiro, and their PhD trainees Anshul Sinha and Sana Naderi. Hosts: Vincent Racaniello and Angela Mingarelli Guests: Corinne Maurice, Jesse Shapiro, Anshul Sinha and Sana Naderi Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Phage and colitis (Microbiome) Origins and evolution of Lassa virus (Cell) Phage replication in human gut microbiota (iScience) Phages in infant gut (ISME J) Early SARS-CoV-2 transmissions in Quebec (Genome Med) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
Today Dr. Steffanie Strathdee, Associate Dean of Global Health Sciences at UC San Diego and Co-Director at the Center for Innovative Phage Applications and Therapeutics, will chat with us about how bacteriophages—viruses that attack bacteria—changed her life and are becoming part of our future. Host: Mark O. Martin Guest: Steffanie Strathdee Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A fun video about bacteriophages. A pretty solid overview about bacteriophages. An article about the history of bacteriophages. An article about a truly prophetic book—“Arrowsmith”--- from 1925, by Sinclair Lewis, about using bacteriophages to fight disease. A wonderful TED talk about the rise of antibiotic resistant pathogens by Maryn McKenna. A nice overview of ESKAPE pathogens and antimicrobial resistance. A link to a recent talk given by Dr. Strathdee. A link to Dr. Strathdee's recent book, “The Perfect Predator.” A super recent and quite wonderful review article about phage therapy by Dr. Strathdee. The SEAPHAGES program (which I always wanted to be part of!!) Ry Young's laboratory website. Dr. Strathdee's faculty website. Dr. Strathdee's Wikipedia page! A link to the website of the Center for Innovative Phage Applications and Therapeutics (IPATH). Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
In episode 11 of The DNA Papers we revisit a paper describing a famous experiment performed by Alfred Hershey and Martha Chase which combined the atomic-age tools of radioisotopes with an ordinary kitchen blender to show that DNA alone, and not protein, was the carrier of hereditary information: Hershey, Alfred D., and Martha Chase. “Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage.” The Journal of General Physiology 36, no. 1 (1952): 39–56. By using radioisotopes to separately label the DNA and protein components of a bacterial virus and demonstrating DNA's central role in the earliest stages of viral replication inside a bacterial cell, Hershey and Chase's 1952 paper provided powerful evidence about the chemical nature of the gene, and gained a well-deserved place among the classics in the history of DNA science. Here to share their ideas and opinions about the history and significance of this paper are: Angela Creager, Princeton University Geoffrey Montgomery, Independent Science Writer William Summers, Yale University See also a collection of Resources. See also a collection of resources on this topic at https://www.chstm.org/video/144. Recorded on Oct 24, 2023.
In this episode, I interview Dr. Jessica Little from Brigham and Women's Hospital and Dana Farber. We talk about CAR-T cells and infections and also about the logistics of using bacteriophages for tough to treat infections.
In the latest episode of Fish n' Bits, host Tony Chen delves into the world of bacteriophages and their potential to revolutionize the aquaculture industry. Amidst growing antibiotic resistance concerns, this episode offers a deep dive into the history, science, and future of phages, particularly in the context of salmon farming. Listeners will learn about the promise of phage therapy as a sustainable solution to combat bacterial infections such as winter wounds in fish, with a spotlight on ACD Pharma's innovative research in the field. Learn about the significant role phages could play in reducing global antibiotic use and improving animal welfare. This one's a must-listen for anyone interested in the intersection of biotechnology and aquaculture - let's dive in! See graphs & more on our blog post --> Read Now
Nels and Vincent take apart an amazing symbiosis consisting of two bacteria, one bacteriophage, and seven different genomes all within a single-celled alga. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server •A single crowded cryptomonad cell (Curr Biol) •Letters read on TWiEVO 94 Science Picks Nels – What happened at NIH during the last government shutdown Vincent – Geneticist J. Craig Venter: ‘I consider retirement tantamount to death' Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv
TWiV describes how a viral capsid protein activates a bacterial innate immune system that interferes with protein synthesis, and human-associated redondoviruses that infect the commensal protozoan Entamoeba gingivalis. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Anti-phage defense via capsid detection (Nature) Redondoviruses infect commensal amoebae (Cell Host Micro) A host for redondoviruses (Nat Rev Micro) Letters read on TWiV 1039 Timestamps by Jolene. Thanks! Weekly Picks Dickson – “Cosmic Time Machine” Netflix documentary Kathy – Antarctican accents Rich – Cymothoa exigua, or the tongue-eating louse, Week of wonder: The case for preserving parasites Jolene – Perspective article on best practices for improving graduate admissions Vincent – Why Chandrayaan-3 landed near the moon's south pole — and why everyone else wants to get there too Listener Picks Douglas – On Climate Change and (Active) Climate Management Matt – This Scientist Tracked Bats for Decades and Solved a Mystery About a Deadly Disease Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
KSQD 6-10-2023: The very long list of diseases linked to gum disease; the oral microbiome is thoroughly covered; The side effects of using mouthwash - more diseases like cardiac conditions are also linked to mouth microbiome; Caller complains about cost of dental care, even with insurance, and other mouth wash options; Take probiotics if given antibiotics with dental procedures; Problems of major infections deep in the roots of teeth, antibiotics and using bacteriophage and other treatments
KSQD 5-10-2023: New recommendation suggest starting mammograms for breast cancer screening at age 40 -- statin use also discussed; Superbugs found in L.A. wastewater -- explanation of the spread of antibiotic resistance; Evidence that Bronze-age people used mind-altering substances such as atropine and scopolamine; A transgender woman has a story about not being able to get a PSA test; Do stem cells from Wharton's jelly injected into your spine really work for pain? More about statin use in elders; Phage treatment as an antibacterial agent and can be used to identify a bacterial species; Your microbiome can reveal what diet you are on and how they affect hormones
KSQD 4-26-2023: Is Juven supplement a good product? Manganese contamination in the water in the Central CA valley; Excessive exercise can cause metal toxicity in mitochondria; Tick bite can cause a reaction to its saliva and doesn't indicate Lyme disease; What treatment is appropriate for a hamstring injury? Drugs to treat post-operative adhesions; What are the health benefits of Radishes? Is Stevia a good alternative to sugar? The history of using bacteriophages, viruses that attack bacteria, as antibacterials; Appropriate amounts Estrogen in creams and suppositories; Low level electrical stimulation helps wound healing
Part 4 - Forum on Circular Water Economy at NYU with WEF: Welcome back SDG Talkers!! Thanks for joining us for another episode of highlighting change makers and their inspirational work towards the United Nations Sustainable Development Goals (SDGs)! Thanks for joining us for our mini series recorded at the Forum on Circular Water Economy hosted at NYU in partnership with the Water Environment Federation and the NYU Department of Civil and Urban Engineering. In This Mini Series: You'll hear from students attending: Manhattan College Columbia University NYU The University of Missouri We chatted with Mwale Chiyenge - an Environmental Engineering Ph.D. Candidate at New York University. Listen now to discover more about her research on bacteriophage and sunlight inactivation! Let's get SDG Talking!! Got a good story or want to collaborate? Send us an email at sdgtalkspodcast@gmail.com and we will get back to you as soon as we can! And don't forget to check out our Virtual Roundtables on our website! Instagram | Facebook | Twitter | LinkedIn
Episode Notes Drs. Saima Aslam (@DocSaimaAslam) and Daria Van Tyne (@DariaVanTyne) join Dr. Rachel Britt (@RachelBPharmD) for a discussion on bacteriophage therapy! Tune in for a review of their role in therapy, logistical considerations, the future of phage therapy, and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
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