Podcasts about IFM

Beta-glucans might be one of the most overlooked levers in immune resilience, and that has major implications for longevity. Talking with my long-time friends and colleagues Drs. Bob Rountree and Chris D'Adamo reminded me just how powerful this molecule truly is. The clinical reach here is stunning, from immune aging and cancer support to vaccine response, gut–brain effects, and overall resilience. What struck me most is how beta-glucans help the innate immune system respond more effectively over time, from overtraining and chronic infections to vaccine responsiveness. Clinicians really need this on their radar. I think you're going to find this conversation eye-opening. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Bob Rountree, MD, is a leading figure in integrative and functional medicine with more than 40 years of clinical experience. Medical Director of Boulder Wellcare and long-time IFM faculty, he is widely published and a respected educator in personalized medicine, botanical therapies, and immune health. Chris D'Adamo, PhD, is a research scientist and epidemiologist focused on how nutrition, lifestyle, and environmental factors influence health. An Assistant Professor at the University of Maryland School of Medicine, he has led numerous clinical studies, published widely, and is a trusted advisor and educator in integrative and lifestyle medicine. THANKS TO OUR SPONSOR BetterWay Health (Consumers) BWHLabs (Practitioners) WEBSITE: http://bwhlabs.com/kara EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Book a practitioner call and receive a complimentary bottle of beta-glucan to try personally or with a patient at http://bwhlabs.com/kara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Dr. Kela Smith overcame her own unexplained infertility at 36 and had her second baby at 40. Now she's helping couples worldwide understand why fertility struggles are skyrocketing. We dive into the real culprits - chronic stress, environmental toxins, and gut health issues - plus her foundational Hormone Puzzle Method. She shares her Magic Plate nutrition approach, how to spot hormone-disrupting products in your home, and why belief in your body's healing ability comes first. Whether you're trying to conceive or just want to optimize your health, this conversation gives you practical tools to work WITH your body instead of against it. For the complete show notes, links and transcripts, visit inspiredliving.show/220

Today, I am delighted to be joined by a friend and colleague, Mike Mutzel.  Mike has a master's in Clinical Nutrition from the University of Bridgeport. He is a graduate of the IFM, applies functional medicine in clinical practice, and is a consultant lecturer who teaches leading-edge science in a concise format for progressive clinicians to prevent chronic diseases.  In our discussion, Mike and I unpack the benefits of creatine monohydrate, highlighting the importance of ensuring the products we use are free of impurities. We explain how creatine monohydrate gets created, answer many listener questions, and describe current research specific to creatine monohydrate, discussing ways to support bone health, navigate dosing, and how to troubleshoot.  This conversation with Mike Mutzel is truly invaluable, and I look forward to having him back on the podcast to dive a little deeper into the science.  IN THIS EPISODE, YOU WILL LEARN: How creatine supports energy production across muscles, the brain, and other organ systems Why vegetarians and vegans should take creatine What to consider when choosing high-quality creatine supplements Dosing strategies based on diet, exercise, sleep, and individual needs How taking creatine with electrolytes while exercising can improve absorption Benefits of supplementing with amino acids alongside creatine for illness, recovery, or when protein intake is low Adjusting your creatine dosage for sleep, travel, or exercise demands How creatine supports bone and muscle health  The value of creatine for the eyes and ears Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Mike Mutzel On his website YouTube Instagram High Intensity Health Podcast Creatine Research: Creatine in Women's Health: Bridging the Gap From Menstruation Through Pregnancy to Menopause Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial

I have Andie Crosby with me again for the second part of a two-part series on why cardiovascular health is the number one longevity lever for women.  Today, in Part 2, we explore how a healthy endothelial glycocalyx matrix helps your body produce more nitric oxide, which supports energy, sexual vitality, and even skin radiance. We also explain what could damage your ability to produce nitric oxide naturally. If you have not yet done so, please listen to Part 1 first, to learn about the endothelial glycocalyx matrix before listening to Part 2. How to Support Nitric Oxide Production Maintain a healthy glycocalyx through diet, exercise, and lifestyle Test your nitric oxide levels to know if you are deficient Supplement strategically if your levels are low  Exercise regularly to increase nitric oxide during activity and improve recovery afterward Bio: Andie Crosby Andie Crosby is a seasoned business leader and passionate advocate for health and longevity.  After decades leading marketing and brand development for companies like Nike, Apple, and Procter & Gamble, her focus shifted in her 40s when she experienced firsthand the impact of hormonal changes, inflammation, and the power of nutrition to transform health.  A simple elimination diet revealed how profoundly food and lifestyle impacted her well-being, sparking a deep curiosity about health and healing.  This led her to The Institute for Functional Medicine, where she became the first Chief Marketing Officer.  Over ten years, Andie built IFM's marketing and partnerships teams, driving a 13-fold increase in practitioner education and advancing personalized, systems-based care.  Today, as President of Calroy Health Sciences, Andie leads innovation in cardiovascular and joint health.  Her mission is to raise awareness of the vascular system's foundational role - not only in disease prevention but also in longevity, brain health, and performance. She believes we have the tools to change the trajectory of our healthspan and empowers people to take control by asking the right questions.  Andie brings a relatable, purpose-driven perspective on living longer, better, and embracing midlife as a powerful opportunity for health transformation.  In this episode: What is nitric oxide? Why the glycocalyx is critical for nitric oxide production and blood vessel function How nitric oxide affects blood pressure, circulation, sexual health, and recovery after exercise  How aging and lifestyle choices reduce natural nitric oxide  How to monitor your nitric oxide level  The benefits of targeted supplementation  Why proactive cardiovascular care is crucial Links and Resources: Use CODE BERGAMOT to get 10% off ⁠⁠⁠Citrus Bergamot⁠ Use CODE BERBERINE to get 10% off ⁠⁠Berberine⁠ Guest Social Media Links: Calroy Health Sciences on Instagram Calroy Health Sciences on Facebook Relative Links for This Show: ⁠Use this link for 10% off⁠ (And a Free Bag of Oral Microbiome Gum) Follow Your Longevity Blueprint  On Instagram| Facebook| Twitter| YouTube | LinkedIn Get your copy of the Your Longevity Blueprint book and claim your bonuses here Find Dr. Stephanie Gray and Your Longevity Blueprint online   Follow Dr. Stephanie Gray  On Facebook| Instagram| Youtube | Twitter | LinkedIn Integrative Health and Hormone Clinic Podcast production by Team Podcast

In this episode, I sit down with functional medicine practitioner Angela Simpson who reveals that up to 80% of her female clients are teetering on autoimmunity without knowing it. We dive into her sustainable 80-20 approach that reverses autoimmune conditions without the stress of perfectionism. Angela explains why comprehensive testing is crucial, how hormonal changes trigger inflammation, and why the gut is "ground zero" for healing. Learn about real client transformations and discover actionable strategies for getting your health back on track—even if you've been told your symptoms are "just hormonal." For the complete show notes, links and transcripts, visit inspiredliving.show/219

I'm excited to have Andie Crosby join me for a two-part series. In Part 1 today, we dive into why cardiovascular health is the number one longevity lever for women and how it is often ignored until it is too late. We explore the critical role of the endothelial glycocalyx, a microscopic life-sustaining structure that is essential for vascular integrity, the inflammation response, and nutrient delivery.  In Part 2 next week, we will cover how nitric oxide supports energy, sexual vitality, and even skin radiance, and factors that could damage the ability to produce it naturally.  How to Protect and Support the Endothelial Glycocalyx Reduce stress  Manage blood sugar   Prioritize sleep Meditate  Take clinically researched supplements.   Monitor your cardiovascular health with diagnostics and lifestyle tracking to catch and reverse arterial aging before it starts to progress. Bio: Andie Crosby Andie Crosby is a seasoned business leader and passionate advocate for health and longevity.  After decades leading marketing and brand development for companies like Nike, Apple, and Procter & Gamble, her focus shifted in her 40s when she experienced firsthand the impact of hormonal changes, inflammation, and the power of nutrition to transform health.  A simple elimination diet revealed how profoundly food and lifestyle impacted her well-being, sparking a deep curiosity about health and healing.  This led her to the Institute for Functional Medicine, where she became the first Chief Marketing Officer.  Over ten years, Andie built IFM's marketing and partnerships teams, driving a 13-fold increase in practitioner education and advancing personalized, systems-based care.  Today, as President of Calroy Health Sciences, Andie leads innovation in cardiovascular and joint health.  Her mission is to raise awareness of the vascular system's foundational role - not only in disease prevention, but also in longevity, brain health, and performance. She believes we have the tools to change the trajectory of our healthspan and empowers people to take control by asking the right questions.  Andie brings a relatable, purpose-driven perspective on living longer, better, and embracing midlife as a powerful opportunity for health transformation.  In this episode: Why traditional health measures do not always reveal hidden cardiovascular risks The value of vascular age testing to uncover silent inflammation and plaque in arteries How lifestyle and stress factors can silently impact heart health over time. How perimenopause and hormonal changes dramatically increase cardiovascular risk in women Why cardiovascular disease is often overlooked until it's too late What advanced diagnostics can reveal beyond a standard blood panel How emerging knowledge about the endothelial glycocalyx is reshaping our understanding of vascular health The benefits of supplements, meditation, stress management, and improving your diet to reverse arterial aging Links and Resources: ⁠⁠Your Longevity Blueprint Omega 3s – 60 capsules ⁠https://yourlongevityblueprint.com/product/coq10-100-mg/ Guest Social Media Links: Calroy Health Sciences on Instagram Calroy Health Sciences on Facebook Relative Links for This Show: Use this link for 10% off (And a Free Bag of Oral Microbiome Gum) Follow Your Longevity Blueprint  On Instagram| Facebook| Twitter| YouTube | LinkedIn Get your copy of the Your Longevity Blueprint book and claim your bonuses here Find Dr. Stephanie Gray and Your Longevity Blueprint online   Follow Dr. Stephanie Gray  On Facebook| Instagram| Youtube | Twitter | LinkedIn Integrative Health and Hormone Clinic Podcast production by Team Podcast

Dr. Jen Pfleghaar joins me today to break down why your menstrual cycle is actually the key to optimizing your workouts, timing your nutrition, and finally making progress with stubborn weight loss. As an emergency medicine physician who transitioned to integrative medicine after reversing her own Hashimoto's, Dr. Jen brings both clinical expertise and real-world experience. She explains why the "hustle harder" mentality works for men but can backfire for women, especially during perimenopause. You'll learn why your stress resistance changes throughout your cycle, why daily intermittent fasting might sabotage your goals, and how to time everything from HIIT workouts to longer fasts. We also dive into why every woman needs to lift weights and red flags about hormone advice on social media. If what used to work isn't working anymore, this episode gives you a new framework for working with your body's rhythms. For the complete show notes, links and transcripts, visit inspiredliving.show/218

What if everything you've been told about cancer treatment is leaving out the most important piece? After healing her own breast cancer 100% naturally despite living what most would call a perfect clean lifestyle, Katrina discovered that one-size-fits-all medicine - whether conventional or alternative - fails because it doesn't address YOUR unique root causes. In this episode, we break down her comprehensive 10-part framework for building an individualized cancer recovery team. We explore why PET scans use glucose to find cancer yet patients are told diet doesn't matter, how stress can sabotage even perfect nutrition, and the shocking truth about what most oncologists never test. Whether you're facing a diagnosis or supporting someone who is, this conversation gives you the tools to take control of your health journey through collaborative care that honors both your body's wisdom and medical expertise.For the complete show notes, links and transcript visit inspiredliving.show/217

Welcome to the CanadianSME Small Business Podcast, hosted by Kripa Anand. Today, we explore digital advertising and marketing strategy, focusing on how ambitious brands can transform their ad spend into predictable profit and sustainable growth.Joining us is Dave Taylor, Co-founder of In Front Marketing (IFM). With over 12 years of experience in marketing and digital media, Dave built IFM on the principle of transparency and measurable results. Now celebrating 10 years in business, IFM represents major organizations including the Calgary Flames and all five C.S.E.C. sports teams, helping businesses make data-driven marketing decisions.1. From Corporate to Entrepreneurship: How Dave's journey shaped IFM's mission for transparent, measurable results.2. Marketing Strategy for 2025: Steps for aligning ad strategy with real business growth and customer acquisition goals.3. Tracking ROI: The key performance metrics every business should monitor for impactful advertising.4. Community and Growth: How IFM's local roots and partnerships fuel success across Canada and the US.5. Future of Digital Marketing: IFM's vision for innovation, custom digital solutions, and growth-focused strategies.Special Thanks to Our Partners:RBC: https://www.rbcroyalbank.com/dms/business/accounts/beyond-banking/index.htmlUPS: https://solutions.ups.com/ca-beunstoppable.html?WT.mc_id=BUSMEWAGoogle: https://www.google.ca/A1 Global College: https://a1globalcollege.ca/ADP Canada: https://www.adp.ca/en.aspxFor more expert insights, visit www.canadiansme.ca and subscribe to the CanadianSME Small Business Magazine. Stay innovative, stay informed, and thrive in the digital age!Disclaimer: The information shared in this podcast is for general informational purposes only and should not be considered as direct financial or business advice. Always consult with a qualified professional for advice specific to your situation.

The biggest hormone myth is finally being debunked, and it's kept millions of women suffering needlessly. I'm talking with Dr. Deb Matthew about the shocking truth: estrogen actually protects against breast cancer, with studies showing a 24% reduction in risk. For 20 years, women have been denied hormone support based on a completely misinterpreted study. We dive deep into how hormone imbalances fuel autoimmune conditions, why your doctor might still be afraid to help you, and what you need to know to advocate for yourself. If you've been told you're "too young" or "too old" for hormones, or that feeling exhausted and irritable is just "normal aging," this conversation could change everything. You deserve to feel resilient, not depleted.For the complete show notes, links and transcript visit inspiredliving.show/216

Ever wonder why you can't stop craving sugar and carbs no matter how hard you try? It's not about willpower; it's about the wrong bacteria controlling your gut. Paul Barattiero, founder of Echo Water and pioneer in hydrogen therapy, reveals the shocking truth behind those relentless food cravings. Your gut should naturally produce 10-12 liters of hydrogen gas daily through proper fermentation, but most of us are nowhere near that. In this conversation, Paul shares how he accidentally discovered hydrogen water while desperately trying to heal his wife's severe health issues. What he found changed everything: 96% of your gut bacteria need a specific electrical environment to thrive, and when they don't get it, the wrong bacteria take over - literally controlling what you crave. I dive deep into the science behind why your microbiome needs negative electrical potential, how hydrogen water creates the perfect terrain for healing, and why you might finally be able to eat foods you've been avoiding for years. This isn't another wellness trend… We're talking about 1,500+ studies and real solutions for chronic inflammation and autoimmunity!For the complete show notes, links and transcripts visit inspiredliving.show/215

After 35 years in medicine, Dr. Joe Jacko has seen it all - and he's ready to tell you what the medical industry doesn't want you to know. In our conversation, he breaks down why patients only get half the information they need, how drug studies use misleading statistics, and why evidence-based medicine has become cookbook medicine driven by insurance profits. But this isn't just criticism, it's empowerment. We discuss Blue Zone residents living to 100 without knowing medical science, why purpose can outweigh poor health markers, and practical strategies for advocating for yourself in medical appointments. Dr. Jacko now runs a comprehensive wellness clinic proving that lifestyle medicine works better than pills for chronic conditions. Key topics: patient empowerment, lifestyle medicine, autoimmune healing, finding integrative doctors, Blue Zones longevity secrets, and why gentle movement beats over-exercising.For the complete show notes, links and transcript visit: inspiredliving.show/214

Chris Burres, chief scientist at MyVitalC, sits down with me to expose a shocking truth about the supplement industry. Peer-reviewed research shows 50% of supplements don't contain what's on their labels - and Chris tested 22 ESS60 products to prove it. We dive deep into the Nobel Prize-winning ESS60 molecule that extended rat lifespans by 90% with zero tumors, how it works in your mitochondria to buffer oxidative stress, and why manufacturing integrity matters more than marketing claims. Chris also shares his personal migraine transformation story and explains why mindset journaling might be the most important longevity practice you're not doing. This conversation will change how you think about cellular health and supplement quality forever.For the complete show notes, links and transcript visit inspiredliving.show/213

Kréta IFM nyelvtanulási felület-módszer. Gubáné Csánki Ágnes stratégiai vezető - Manna Délelőtt Péter Petrával 2025. 10. 08. by MannaFM

Từ khi trở thành công xưởng của thế giới, hàng rẻ sản xuất tại Trung Quốc đã bóp chết một phần lớn mạng lưới công nghiệp châu Âu, nhiều nhà máy trên toàn nước Pháp phải đóng cửa, sa thải nhân viên. Bước kế tiếp để Trung Quốc « triệt hạ đối thủ cạnh tranh » phải chăng là nhắm tới các hệ thống phân phối vào các cửa hàng đủ mọi cấp ?  Đồ đắt và rẻ tiền cùng trong một cửa hàng Là một trong 5 nhãn hiệu quần áo « phổ biến nhất », được người Pháp ưa chuộng nhất, Shein chuẩn bị khai trương gian hàng đầu tiên ngay giữa lòng « kinh đô của ngành thời trang » Paris. Đầu tháng 11 tới đây, cửa hàng lớn và cũng là một trung tâm thương mại tiêu biểu nhất của Paris sẽ dành hẳn một tầng lầu với 1.200 mét vuông làm tủ kính trưng bày hàng bình dân, mang nhãn hiệu Shein của Trung Quốc. Giá trung bình một món hàng trong không gian trưng bày này là 9 euro. Để mở một gian hàng cố định đầu tiên, trực tiếp giao lưu với khách hàng, Shein đã chọn kinh đô của ngành thời trang thế giới. Tập đoàn Trung Quốc khởi nghiệp từ Quảng Châu này không chỉ còn là một nhà « phân phối trên mạng », với các dịch vụ mua bán trực tuyến, cũng không chỉ hài lòng với những chiến dịch tiếp thị gây chú với những cửa hàng « tạm hoạt động trong một thời gian cố định ». Lần này Shein nhắm tới cửa hàng BHV ngay giữa lòng Paris, cách không xa tòa thị chính của thành phố. Bước kế tiếp, Shein sẽ hiện diện luôn cả ở các cửa hàng của hệ thống Galeries Lafayette tại 5 thành phố (Dijon, Grenoble, Reims, Limoges và Angers). Tin hãng thời trang giá rẻ Trung Quốc Shein chen chân vào BHV gây chấn động và làm dấy lên nhiều tranh cãi. Được thành lập từ năm 1860 dưới tên gọi Bazar de l'Hôtel de Ville – tức là cửa hàng Bách Hóa Khu Hotel de Ville, rồi được đổi tên thành BHV kể từ năm 2013, cửa hàng nổi tiếng này ở quận 4 Paris, từng là « thánh đường mua sắm » của cả một tầng lớp giàu có và trưởng giả. Giữa thế kỷ 19, BHV cũng như nhiều cửa hàng lớn khác của Pháp - Le Bon Marché, Printemps, Galeries Lafayette, La Samaritaine ... ưu tiên nhằm phục vụ những khách hàng khó tính với nhu cầu tiêu thụ có chọn lọc. Cõng rắn cắn gà nhà Vậy làm thế nào nhãn hiệu hàng may mặc « rẻ tiền » Trung Quốc lại chen chân được vào một cửa hàng lớn của Paris? Tạo chỗ đứng cho « hàng rẻ » Trung Quốc ngay giữa một kinh đô thời trang lâu đời nhất thế giới này thậm chí bị xem là một sự « xúc phạm ». Kèm theo đó là những câu hỏi liệu rằng hàng Trung Quốc có tuân thủ những chuẩn mực của Pháp và châu Âu về lao động và môi trường hay không ? Liệu rằng những « tượng đài mua sắm hạng sang, chuyên dành phân phối hàng có chất lượng » như các cửa hàng lớn của Pháp có đang « nối giáo cho giặc » sau khi đã giết chết các hãng may mặc, các nhà máy dệt may của Pháp giờ đây Trung Quốc bắt đầu tấn công luôn cả đến các hệ thống phân phối ? Trả lời báo Le Figaro, giám đốc điều hành Shein xem việc chọn nước Pháp là một « thông điệp mạnh mẽ », là một « bước đi tự nhiên » do Pháp là thị trường lớn nhất của Shein. Tại đây, theo cơ quan tư vấn EY-Parthenon, Shein đứng thứ tư trong số những nhãn hiệu được công chúng Pháp ưa thích. Riêng trong lĩnh vực may mặc thì đứng hạng 5 theo bảng xếp hạng của Viện nghiên cứu thời trang IFM. Hai hệ thống phân phối trên mạng của Trung Quốc là Shein và Temu cộng lại chiếm 16 % thị phần các dịch vụ trực tuyến trong ngành may mặc của toàn nước Pháp. Trả lời đài truyền hình Pháp France 5, Frédéric Merlin, chủ nhân và cũng là đồng sáng lập viên tập đoàn SGM hiện đang nắm giữ cửa hàng BHV Paris giải thích ý nghĩa của việc mở cửa BHV cho hàng rẻ Trung Quốc dưới nhãn hiệu Shein xuất phát từ ý đưởng muốn kết hợp những gì tốt đẹp nhất từ hai mô hình kinh doanh : « Chúng tôi đang làm thay đổi thể thức vận hành của Shein. Đương nhiên không thể là một giải pháp hoàn hảo nhưng chúng tôi đang tìm một hướng đi mới. Hiện tại khi mua bán, chúng ta hoặc là đến các cửa hàng, hoặc là giao dịch trên mạng và hàng được chuyển đến tận nhà. Với Shein hiện diện trong khuôn viên của cửa hàng BHV chúng tôi kết hợp giữa hai hình thức mua bán nói trên để thu hút khách hàng đến trung tâm của BHV : họ nhìn tận mắt, đánh giá chất lượng quần áo của Shein. Chúng ta có thể mua hàng tại chỗ, rồi tiếp theo là tin tưởng hơn vào nhãn hiệu này khi cần đặt mua trên mạng. Trong chiều ngược lại thì những người khách từ trước đến nay chỉ giao dịch với thương hiệu này qua mạng thì bây giờ họ sẽ tò mò hơn, tìm đến trung tâm của BHV … Chúng tôi hy vọng lượng khách lui tới các cửa hàng cao cấp của Pháp sẽ nhiều hơn. Cũng Frédéric Merlin giải thích tiếp là BHV muốn khai thác những lợi thế của đối tác Trung Quốc này : « Shein là một cỗ máy rất xuất sắc về tiếp thị, họ sử dụng thuật toán tìm kiếm rất tài tình để quảng cáo, để giới thiệu sản phẩm… Nhờ thế mà một khách hàng ở Rennes, miền tây nước Pháp sẽ dễ dàng mua được những mặt hàng thường chỉ có ở thành phố Dijon, mãi tận miền đông nước Pháp chẳng hạn. Nhờ vậy các cửa hàng không cần phải có các kho hàng quá lớn, bớt tốn kém ở khâu này ». Chuẩn mực lao động và môi trường : Shein khó trấn an công luận Thống kê của hiệp hội dệt may Pháp, mỗi năm Pháp mất đi 40.000 việc làm chỉ riêng trong ngành dệt may vì hàng rẻ Trung Quốc. Các nhà máy thi nhau đóng cửa. Thậm chí số khách lui tới các cửa hàng, các trung tâm thương mại cũng có phần vắng đi nhiều do bị các nền tảng mua bán trên mạng cạnh, do đang bị « hàng rẻ Trung Quốc nhận chìm ». Trước những cáo buộc hàng Trung Quốc không tuân thủ chuẩn mực quốc tế về lao động, bóc lột lao động cưỡng bức ở Tân Cương, là hàng không thân thiện với môi trường … và nhất là cạnh tranh bất bình đẳng với hàng Pháp, hàng châu Âu. Frédéric Merlin đưa ra câu trả lời không mấy thuyết phục : « Shein là một nền tảng giao dịch cho phép các nhà sản xuất tư nhân Trung Quốc bán trực tiếp những sản phẩm làm ra. Đồng thời nhãn hiệu này cũng có riêng những cơ sở may mặc của họ và chúng tôi chỉ tập trung vào hàng sản xuất từ các cơ sở của Shein mà thôi nhưng đó cũng là những xưởng may cung cấp quần áo cho các nhãn hiệu của Pháp … » Vẫn trên đài truyền hình France5, Frédéric Merlin tự hào khoe rằng, gian hàng Shein trong trung tâm thương mại BHV tập đoàn SGM ông điều hành sẽ cho phép tạo thêm khoảng 200 việc làm mỗi năm và không có chuyện vì hàng rẻ Trung Quốc cũng được phân phối trực tuyến mà khách hàng ở Pháp bớt lui tới các cửa hàng mua sắm. « Không phải ai cũng có điều kiện để mua hàng đắt tiền. Hơn nữa tôi tin vào những tính đa dạng trong cung cách mua sắm của khách hàng. Những người bước chân vào cửa hàng của BHV hoàn toàn có thể vừa mua quần áo của Shein, vừa mua những túi xách tay hay mua son phấn … » Có nhiều câu hỏi chung quanh mối hợp tác Vào lúc mọi chú ý đang đổ dồn về hợp tác giữa Shein và BHV cũng như với hệ thống cửa hàng Galeries Lafayette sắp tới đây, thì một tên tuổi khác của ngành may mặc của Pháp là Pimkie từ tháng 9/2025 đã chính thức bắt tay với tập đoàn Trung Quốc này. Pimkie là một hệ thống chuyên phân phối hàng may mặc được giới trẻ ưa thích nhưng đang thua lỗ mà một phần là do các hoạt động mua bán trực tuyến gây nên. Chuỗi cung cấp này liên kết với Shein để cùng « sản xuất và phân phối » qua mạng để đưa ra những « bộ sưu tậm thời trang riêng biệt ». Pimkie chờ đợi đến 2028 hợp tác với Shein sẽ cho phép thu về 100 triệu euro tương đương với 1/3 doanh thu hàng năm của tập đoàn Pháp. Đối với phía Trung Quốc, hợp tác với Pháp là kịch bản lý tưởng. Năm 2024 thặng dự mậu dịch của công xưởng sản xuất thế giới này là 1.000 tỷ đô la - tương đương với gần 1/3 GDP của Pháp. Trong 8 tháng đầu năm nay, kim ngạch xuất khẩu Trung Quốc sang châu Âu tăng hơn 20 %. Trong quá trình phát triển kinh tế, hơn 40 qua, Trung Quốc đã chen chân vào các lĩnh vực như công nghiệp xe hơi, giết chết các nhà máy luyện kim, các nhà máy hóa chất, các hãng dệt may … của Pháp. Cũng Trung Quốc đã trở thành những đối thủ đáng gờm nhất của Pháp nói riêng, Âu Mỹ nói chung trong những lĩnh vực công nghệ tiên tiến và trên thị trường High Tech, trong lĩnh vực chuyển đổi sang năng lượng … giờ đây đến lượt các hệ thống phân phối, các cửa hàng của Pháp trở thành những mục tiêu của tư bản Trung Quốc.  

I'm busting the biggest autoimmune myths with Dr. Cory Rice, who went from solving cold cases in forensics to solving the puzzle of autoimmune disease. This isn't your typical "manage your condition" conversation - we're talking about actual reversal and why these conditions aren't rare anymore (affecting 1 in 10 people!). Dr. Rice explains why 70% of your immune system lives in your gut, why women are disproportionately affected, and reveals his mandatory gut testing approach that's helping patients reclaim their lives. If you've been told there's no hope or you just need to "manage" your autoimmune condition, this episode will change your perspective completely.For the complete show notes, links and transcript visit inspiredliving.show/212

"When my oncologist looked me in the eye and said there's nothing I could do for myself, I knew I had to find another way."In this episode I'm sharing Heather's incredible story of refusing conventional cancer treatment and choosing the metabolic approach instead. At 37, facing vulvar cancer, she declined surgery and radiation, implementing therapeutic ketogenic diet, high-dose IVs, and complete lifestyle transformation. Now cancer-free and helping others, she reveals why blood sugar dysfunction drives both autoimmunity and cancer, and the one test that shows metabolic health in 94% of people. We dive deep into how our biography influences our biology and practical steps you can take today to assess your own metabolic health.For the complete show notes, links and transcript visit inspiredliving.show/211

Meet Jess Faulds, who was diagnosed with MS at just 15 years old. After failing four different disease-modifying therapies, she underwent an intense stem cell transplant at 26 that essentially wiped out her immune system. Six years later, she's living symptom-free with no relapses or progression. As a personal trainer and holistic nutrition coach, Jess shares the practical strategies that supported her healing: staying active through treatment, plant-based whole foods nutrition, her "if you bite it, you write it" food tracking method, and mindset tools like "comparison is the thief of joy." Whether you're dealing with autoimmune issues or want to optimize your health, this conversation offers hope and actionable wisdom.For the complete show notes, links and transcripts, visit: inspiredliving.show/210

Shawn takes a look at the ET 200SP line of Distributed I/O from Siemens in Episode 19 of The Automation Show, Season 2. For any links related to this episode, check out the “Show Notes” located below the video. Watch The Automation Show from The Automation Blog: Listen to The Automation Show on The Automation Blog: The Automation Show, Season 2 Episode 19 Show Notes: The links mentioned in the video are listed below: ET 200SP Website ET 200SP Manual Collection Shawn’s Siemens S7 Course Programming Note: Due to scheduling conflicts, episodes 17 & 18 and releasing after episodes 19-2x :-O Read the transcript on The Automation Blog: (automatically generated) Shawn Tierney (Host): Hey everybody. Welcome back to the show. My name is Shawn Tierney from Insights and Automation. And today, we’re talking e t 200 s p distributed IO from Siemens. Before we go any farther, I do wanna thank Siemens for sending in the samples and for sponsoring this episode so it will be ad free, and that’s as far as it goes. Everything else is my own opinion and thoughts. And, although I do appreciate them making this ad free and sending in the samples because I wanna be able to show them to you if I didn’t have them. And, this is one of the reasons I’m doing this is I just put these hands on demos together for my students who come out to the automation school for hands on training. So I wanted to have something they could bring to their station and program with an s seven twelve hundred or 1,500. And, so I’m creating a bunch of these, and you’ll see more and more of these as the weeks go on. But in any case, I we previously covered a couple on IFM, but now I’m doing the e t 200 s p. So we’ll take a closer look at the hardware in a little bit. But But before we get into the hardware, I did wanna run through some slides that do a great job of explaining what e t 200 s p I o is. And, again, I call it distributed IO, not remote IO because here in America, most of us know there is a remote IO product from Rockwell Automation that is trademarked, Rockwell. So we don’t wanna confuse people by using the term remote IO when possible. So let’s go ahead and go to the slide deck now. And, the first slide is and, again, these this is a slightly of a couple three year old slide deck from Siemens that we’re gonna be going through. And, you know, the first thing is, hey. E t 200 s p and e t 200 m p I o or I p 20 in cabinet I o. They’re not on machine or machine mount IO. And, of course, the e t 200 MP is the full size IO that’s about the same size as the 1,500, whereas the SP is the smaller. They’re like the slice IO you see from all the different vendors. A matter of fact, a couple of big vendors are coming out with new IO this fall or have already come out with it, and we’ll be covering those as well in the coming weeks. But today, we’re focusing on e t 200 s p. And so I wanted to, talk about, you know, this is a marketing slide that Siemens puts in their presentations, and it makes sense. All the vendors wanna have IO for all the different applications, and Siemens is no different. And, actually, they got some stuff that other vendors don’t have. But I’m gonna go right beyond this one and jump right into, you know, the main selling points of this product line where it’s compact, it’s fast, it’s any of NG efficient, it’s easy to wire, and I can attest to that having done three, four hundred wires here. It was very easy to wire. I really liked it. They say it has a great environmental coverage. There actually is, some extreme modules. We’ll talk about that towards the end. And then built in diagnostics. Again, depending if you buy the high function and standard or basic modules, right, will depend on what kinda diagnostics you get. In any case, here is what it looks like now. The coloring of this slide, I think that the pictures colors the gray is a little lighter, almost it’s almost like a light green. It’s darker in person as we saw. Let me switch over here. As you can see here. So, I don’t know what’s going on with that, but one of the things you do see on this slide is, one of the first things you’ll notice is a fail safe module, so safety modules. So, yes, you can mix standard and fail safe modules in the same rack or same lineup. The other thing you’ll notice is it’s compact like most of the Slice I o that’s out there. Energy efficient ruggedness, there is an extreme version of this available. Intelligent, you can get high functionality modules. Right? Push in terminals, which I really liked, very easy to use, tool free connections. Of course, if you’d put a wire in the wrong place, which happened to me once or twice out of 400 wires, you can use a screwdriver and get it out really quick, and then, reduced parts of variance. So that’s their marketing on this product line, but I also wanna call attention all the different ways you can actually mark up the products. You can put labels in the front, right in the front of the module itself. You can put labels on top and on the back as well. So a lot of different labeling options is also a color coding you can put over the terminals as well. We’ll see that a little bit later. In any case, this is the physically how it goes together. So first of all, it doesn’t you they don’t all just slide together like tongue and groove. You do have to put them on the DIN rail and slide them into each other from right to left. So keep that in mind. Okay. And we always start the leftmost part is what we call an interface module. And so think of that if you’re a Rockwell guy, that’s your adapter. Okay? Now the interface module, most of these take a bus adapter. In other words, you can choose copper or you can choose fiber, or you can choose copper and fiber. And I love this design because, well, I’m sure it adds a little cost to the product. Being able to swap out copper for fiber if you need to or do one copper one fiber if you need to, I think it’s a great idea. That kind of flexibility is great. Now there is a low cost interface module that has that bus adapter built in, but in any case, most of them, as you’ll see, what was what I’ll show you here on the workbench, it’s module. You choose the one you want and this basic and advanced and we’ll take a look at all those. Then you have the bases and the IO modules and we’ll look at this in real time here on the workbench in a moment, but you can see here the basis of what the IO modules plug into. If you look there on the the fourth item there, it’s just a base module without the IO. And, that’s what clips onto the DIN rail and slides together, and then we stick our IO modules in. Also, share the keying. A lot of people leave that out, but I think it’s pretty cool what they do there. And at the very end, they have something called a server module. The name for this, I’m thinking of servers like a computer server. So I don’t know what happened with the translation there, but it’s like an end cap. If you’re a Rockwell person, it’s like an end cap. You gotta have that at the end. It doesn’t really serve up anything, but, in any case, you gotta have it. So in any case, then you can see kinda how it’s laid out there. Let’s go ahead and go to the next slide here. And, these are all the different type of interface modules they have. So the very basic one, right, if you needed a low cost drop of IO, it only does up to 12 modules, but, you know, it’s an all in one unit with two Ethernet ports built in, and you can use all the modules with it except for safety modules. K. So that’s important to know. Then we have the standard interface modules, which do up to 32 modules. Right? You can use safety with them. You can actually expand them to e t 200 a l if you needed to have some, on machine products or machine mount I o. I’ll show you the a l in a future video. We’re gonna cover that separately. And you can hot swap any single module at a time, which is very cool. And then, of course, if we go to the high featured, we get up to 64 modules. You can multi hot swap, multiple modules. You can actually set it for asynchronous mode so you can get the speeds up to two hundred fifty microseconds. So it’s, very cool there. And you can see the other options there including the CPU, which we will cover. That’ll probably be next week, though. Alright. So, one of the cool features they have is this was new at the time of this, you know, two, three years ago of this presentation is they added a, a unit that actually could use three Ethernet ports. So why would you do that? Well, think of it. Right? You maybe you’re daisy chaining from one interface module to the next and you have a station where you either need a bulkhead connector so you can program from or you have an HMI. You need that third connection. Right? And so this allows you to have three connections. Now the downside of this is you actually have four connections, but you can only use three and I’ll show you what I mean here. Let’s go back to the overhead, and I actually have that module right here. Thank you, Siemens, for sending him in. And you can see I have my two bus adapters, but I can only use three of the four. Okay? So it’s it’s just a limitation. And, you know, I don’t really know why they’re limited to that. I’m sure there’s a reason. I was thinking about that earlier. It’s like, maybe they wanted to prevent this or that or the other thing, but in any case, it’s still cool. It’s so much cheaper than buying a switch and putting it in that place. Well, in most cases, it would be. Right? There’s also the optional, grooves here. Let me switch back. There’s also optional grooves here. I don’t know if you can see them very well. We’ll zoom in later. But that is for, strain relief, if you need to have that as well. You can see those plastic pieces go in, and then you can, you know, zip tie your cables right to them. So very interesting new product there. And then these are all of the different, bus adapters. So you can see there’s, basic ones with two RJ 45 ports, two FastConnect ports. There’s, units with, one RJ forty five one fiber optic and so on. So lots of different options there to choose from. And, again, not a lot of people do this. You have to replace the whole interface module with other companies’ products, like in Rockwood would be an adapter to get a difference. Right? And here, you don’t have to. You just replace the, the, bus adapter. Okay. Now here’s just showing the different type of modules. So if you’re familiar with Siemens, you know, all their modules come well, most of their modules come in different flavors. You have the standard, you have the basic, and you have the high feature. Right? And they’re also showing, a safety module there with the yellow, and then you can also get high speed. So lots of different options here. And we’ll take a look at that. But, they all have different, article numbers or part numbers for us Americans. And so, you know, if you’re in OEM, you’re just doing a lot of clickety clack, maybe you get all the basics. If you’re in process, you’re probably gonna want the high features, advanced diagnostics, and so on. So in any case, and this is what the front of them looks like. Of course, they have digital in and digital out. They have analog in and analog out. They also have what I call specialty. So they have technology modules and communication modules. I love, that they have, BACnet and IO Link and PROFIBUS, Aussie in this form factor as well as conning modules, position modules, energy management, weighing modules, all those different modules. And here’s some of the other things too. So tool free, I did all three or 400 wires. It was all tool free. I just put my wire in. Boom. It clamped a really good across your pool test every single one. Right? And so I’ve been one of the guys who’ve driven hours and hours to find out the problem wasn’t with the product. It was with the guy who wired it. He didn’t screw them down tight enough. So you pool test everyone, make sure they’re in there solidly, and, I didn’t have any problems at all. Very easy to take out. I have a couple that I forgot to run them through the Panduit. I just looped over the Panduit and and over the top of the box. And I’m like, Shawn, if you put it in that way, you won’t be able to close the cover. So So when you’re doing so many, sometimes you get distracted. So in any case, very easy to get them back out if you put them in the wrong and you need to rewire them somewhere else. They say they’re 50% narrower. I would say that versus the e t 200 m p. I think they’re about the same size as, everybody else’s slice IO, very close. And then you can see there the marking, at the bottom. Those reference identification labels, that those are pretty cool, if you need the color code, the wire, terminals. Okay. So let’s go on from there and, this one is really cool too. Now this is a fairly new not everybody knows about this, but this is the multi field bus version of the interface module. I think this is so cool. It does Ethernet p. It does Modbus TCP, and it does PROFINET all in one module. It does set up a little differently. When I was testing it out, I was like, wow. That does set up a little differently than the other interface modules. But, I didn’t have to use the, the separate tool to get it working. So in any case, very cool, and it can talk all three at the same time. So if you had a couple of the of people who needed to listen to the traffic, but you need one station to control it, then, you could have all three running at the same time. I just think that’s so cool. And we do have one here. We’re gonna do it use it first with the Siemens and then maybe use it with the Rockwells if time permits. But, definitely wanna do that, in another episode of the show. But, very cool. I’m I matter of fact, we just, did an episode. It’s not released yet, but, it will be out shortly with the METTLENOTO I n d three sixty, and that also supports multiple protocols. So so cool. I love it when vendors do that all in the same part number. So cool. And so you can see more information about that here. I’m not gonna go into details. We’ll talk about later, when we actually have the episode on that. And another thing I noticed with their high function modules, it says firmware 4.1 and up is that you can, so on the HF modules, you could do module to module communications. So you’re talking, like, screw to screw, like, two hundred fifty microseconds. I think that’s so cool. That’s something else if time permits. In the coming days, we’ll, do a demo on that too if we can get, if we have the time to do it. I just think it’s a cool feature. I’d love to see it in action. There’s other things in here about, other types of modules. I’m not gonna go through all this. This one I thought was pretty interesting. It’s 48 24 to 48 volts AC or 48 volt DC. So eight inputs either AC or DC in those ranges and it has a built in fuse which I think is so important. Right? So, an interesting new module that does both AC and DC. Right? Looked like it was really designed for transportation and that kinda wraps up the PowerPoint slide. And, again, this is just one of many of their lines. Oh, I do wanna mention this. This should have been before that. This is the extreme version of what they call their psi plus extreme, where you get the minus 40 to 70 degrees c. You can install it, up to 5,000 meters. You know, the air is thinner up there. It can, handle salt mist, chemical, active substances. You know, this is a lot of people would think of this as conformally coated. So, you can see all of those different, regulations that the extreme version, makes. Okay? The Ciplas Extreme. So with that, let’s see. Last slide here. So this is just one of many products. So we’ve covered this in the past. We covered the 1,200 to 1,500. This is the t 200 s p. We will be covering the a l and the Eco PN. I think these are both Eco PN, in the future. But with that, I wanna actually give you a physical demo of how this stuff works. So in any case, let me move the modules around here a little bit, and we’ll be zooming in and out. So this is the unit I, I, you know, wired up this weekend, and we’ll zoom in on her. And this is the one that gives you the, up to threes that I put, so you have two bus adapters. Okay? And it’s a little bit wider. If you look at one of the other ones, you can see it’s a lot narrower. Right? That’s actually the multi field bus model, which is about the same size as the standard model. Well, long here, I might as well bring that one in too and show you that one. K. So in any case but, let’s focus on this guy, and, we’ll take a look at I wanted to show you this one because this one also has the analog in, even though I haven’t put the analog operators and make gauges on the panel. I do have them wired up. Right now, I just have them wired to each other. But in any case, so let’s go ahead and zoom in on this a little bit. Okay. First thing you’re gonna notice is the first terminal block here, the first base is is a light style, and then they go to the darker style. And that’s because you can bring power into these light bases. Right? Like an a zero. And, I go through all the part numbers in my course. You guys can find that in the literature. But and it passes power to these other bases. Okay. So you’ll typically start with a light style. You’ll go through as many bases as you can power until you need another or you need isolation until you need another, light style base. And then here, you can see the modules themselves. I love the fact that everything has a QR code on it. So if you need the manual, you just you just, you know, get your phone out and and it’ll link right to it. But I want the wire in here, so I was able to wire everything based on just, the little label here. And again, this is where you can slide in your own labels if you want. And then the indicators here, they all worked when we when we actually do in a next video, we actually do the integration. You’ll see these lights come on. They’re very easy to see. You can also see here some version information. I did run into some of these modules being too new for version 16. So I usually default to version 16 because that’s what I started with. But, if you have 16.1, you can get the new GSD file and it supports most of the I think almost all the new modules. In any case, up here and I do have a mix of new and used because back when I was, getting ready to do this, we had the whole component sort shortage, so I had to pick up some modules myself. But, in any case, you’ll see the type here. Digital in, and this is a basic. Okay? So eight by 24, eight inputs at 24 volts DC. And then you have the digital output, DQ. This is a standard eight by 24. Eight u, I believe that means voltage, and, u for voltage. But in any case and then if we come over here, we have an a q. This is a standard, s t, and this is for UI, so voltage or current. And so you can see those there. And down here is the article number, which we typically refer to as, like, a, catalog number here in The US. K. And so when I’m sending these up, I take a picture of the front of the unit, and that’s what I use to set them up in the software. But in any case, you can also see the versions here as well. I love that all that information is on the front of the module. And then at the top, we already looked at that. And so we already looked at the top. And then over here, we have the server module, or what we may call an end cap here in The US. Alright. So one of the cool things about this, these modules is the keying. So I’m going to take these out just by squeezing in. I’m gonna pull it out, pull this one out too. Okay. And in there, you can see I know the lighting’s a little tricky, but in there, you see those black little wheels, those circular black things? Those are the keys. And you can see how they’re let’s see if I go up to the camera. If I put the overhead light on, it just gives too much glare. So hopefully, you guys can see that. Well, the cool thing about that is that those come pre installed on the modules. Like, they clipped in there really good, and they don’t come loose until you stick them in all the way, and then they stay in the base. And I love that. So you don’t have to turn anything. You don’t have to memorize what position it’s in. You just put the module in and boom. Now I did have a couple modules put in the wrong position, so I was able to get out with a screwdriver, get in that little, notch there and get it out. But you can see there’s two notches in each, but I it doesn’t feel like when I was doing that, it didn’t feel like it was designed for those to be reused. So I probably say that not, but let’s go ahead and try to put this module in the wrong place. Yeah. You can. So, I really like that design feature, automatic keying, and, yeah. That’s great. And they really go in. You’re gonna make sure they’re all the way in, but once they’re in, they’re in. Now let me zoom out a little bit and show you how to take them apart and put them back together. So there are these, push in buttons here on the top. Right? So these latches, these releases. And so what I’ll do is let me push in the first two, the the server module and the module, and I’m gonna slide them to the right. Okay? And I know it has all the, wiring on it. But in any case, that’s how easy it is to assemble and disassemble. Quick or disassemble like this. Okay. And now to get them on and off the DIN rail, I’m gonna push in those two, tabs at the top there. I’m gonna lift the bottom up. Okay. Now I can get it off the DIN rail. Alright. And so when you’re pushing in that top tab, it’s doing two things. Okay? It’s gonna release the, DIN rail, but it’s also gonna release the connection to the module on the side of it. Alright? And so you’re gonna be cognizant of that. Alright? You can’t just release it release the module off the DIN rail. You have to release it from the side as well. Okay. And, you can see that here. Well, let’s see if we can get him off. He’s a little sticky. I don’t know why. He could be used. But in any case, get him off. Okay. And it’s the same for the sky too. Let’s see here. So let’s go ahead and put it back together again. We’ll put the top on first and then we’ll click it on to the bottom. Okay. And then we’ll slide it in. Nice. Then we’ll do the same thing for the server module and cap. Okay. It’s not called the end cap. That’s my race. Okay. And this one, sometimes this might be a useful one. There we go. It’s all in together and working great. You gotta make sure you get those modules all the way in. Okay. And there’s a lot of great, diagnostics when you get the system up and running. It’ll tell you if it’s missing a module. It’ll tell you if you chose the wrong base in the software. If let’s say you chose the light colored base versus the dark colored base. I mean, the new power versus the power pass on. It’ll tell you if you get the wrong firmware or the wrong style. Maybe you chose a standard and it’s a basic. So you get all that kind of stuff that you would normally get when you’re, you know, to make sure you have the right IO modules. And so with that, that is a, look at e t 200 s p. I hope it makes sense to you now. Now if you’ve been using this for a long time, longer than I have, and you have some more tips, please leave them in the comments. I do appreciate everybody who comments on the videos wherever the video is. Also, we do have more content coming out about this. We’re gonna go through each of these in a separate video and get each of these up and running from scratch. And then after that, there’ll be new lessons at the Automation School for anybody who’s interested in maybe a longer version of this with more details and support. Right? So in any case and, of course, if you guys wanna call me and, have a group of your guys come in and do some hands on training, these are actually ready to be used in the training room with all the s seven twelve hundreds and 15 hundreds. So if you wanna do some hands on training. It’s, we’re very unique here because of having the automation show and podcast and blog and all the vendors we work with. We have a lot of equipment that you will find almost in nobody else’s training, rooms. So with that, I wanna thank you all for tuning in. I wanna wish you all good health and happiness. And until next time, my friends, peace. Vendors: Would you like your product featured on the Podcast, Show or Blog? If you would, please contact me at: https://theautomationblog.com/contact Until next time, Peace ✌️  If you enjoyed this content, please give it a Like, and consider Sharing a link to it as that is the best way for us to grow our audience, which in turn allows us to produce more content

This week I'm joined by Dr. Dan Pardi, Qualia's Chief Health Officer, for a fascinating dive into your body's repair system. We explore what's really happening to your stem cells as you age - spoiler alert: they don't disappear, they just get stuck in toxic environments that prevent them from working. Dr. Pardi breaks down the science of stem cell exhaustion, one of the 15 hallmarks of aging, and shares practical strategies to support these ancient repair mechanisms. From the evolutionary origins of stem cells to cutting-edge protocols that work with your body's natural rhythms, this conversation reveals how to optimize your repair system at any age.For the complete show notes, links and transcript visit inspiredliving.show/209

In Today's epidsode CesarRespino.com brings to you a special guest to You Can Overcome Anything! Podcast Show.Mark Sherwood, Naturopathic Doctor (ND) and Michele L. Neil-Sherwood, Doctor of Osteopathy (DO), have a full-time wellness-based medical practice in Tulsa, OK called the Functional Medical Institute where they adopt a whole person approach, which is outcome based looking at each individual's unique needs. Their goal is to lead people down a pathway of true healing. To that end, there are two purposes: 1. To eradicate all self-imposed, choice driven disease conditions, and 2. To eliminate the usage of unnecessary medications. Through their unique clinic, various diagnostic tests are used, healing and prevention of common disease patterns are the norm.The couple has co-authored four Amazon #1 best-selling books, The Quest for Wellness, Fork Your Diet, Surviving the garden of Eatin', The Narrow Road, and Peptides Unlocked (just released). They have been seen on national TV, been quoted on CNN, featured on CBN, and are regular contributors to many national publications. Drs. Mark and Michele appear twice weekly on many TV networks with their show Furthermore. They are also movie producers of the documentary film Fork Your Diet, and other inspirational and faith-based movies: The Prayer List, WWJR, Heaven's Date, and Holy Flix. Two more films have just concluded production – The Last POTUS and Wealthy Soul. Both will come out worldwide in 2025.Their influence also expands into healthy meal and product development called Kingdom Life - with formulations including Kingdom Fuel, Kingdom Kandy, Kingdom Krunch, Kingdom H2, Kingdom Kollagen, Kingdom Energy, Kingdom Colostrum, and Kingdom Kup.With a broad social media network that spans the globe and reaches millions, Drs. Mark and Michele's influence is far reaching. The couple understands the importance of nutrition, medical food & supplementation, exercise prescription, rest, stress management, hormone balance and functional movement. This makes them a modern day “dynamic duo of wellness” and the “original biohackers”.Dr. Michele is a former national physique champion, taekwondo black belt, judo black belt, fitness expert, functional medicine expert. She is a fellow in Osteopathic Internal Medicine and an IFM certified practitioner. Her training is both extensive and expansive. Along with Dr. Mark, she instructs clinicians worldwide on nutrigenomics and nutrigenetics.Dr. Mark has completed training and certifications in age management, nutrigenetics, nutrigenomics, peptide therapy, hormone therapy, stress management, GI health, and immunology. He is a 24-year retired veteran of the Tulsa Police Department, where he logged a decade of courageous service on the department's SWAT Team. He is also a former Oklahoma state and regional bodybuilding champion, and ex-professional baseball player. Additionally, Dr. Mark traveled the world for over 10 years with the world-famous Power Team. Mark is also a motivational speaker whose presentations are sought by audiences nationwide and was a 2022 gubernatorial candidate for Oklahoma.Conect with Mark at www.Sherwood.TVTo Connect with CesarRespino go to:

I'm sitting down with mental health advocate Brian Sachetta to discuss something that affects so many of us: how chronic stress triggers autoimmune flares. Brian breaks down why our nervous systems evolved for acute threats but now struggle with constant modern stressors like social media and work pressure. The key insight? Healing only happens in our parasympathetic state, but we're stuck in fight-or-flight mode.We share practical tools you can use anywhere: breathing techniques, movement, eye exercises, and grounding practices that actually work with your evolutionary wiring instead of against it.For the complete show notes, links and transcript visit: inspiredliving.show/208

I'm obsessed with this conversation. Hali Laricey taught me how to read my CBC with differential like a detective - and you probably already have years of these sitting in your patient portal right now. Those "normal" labs everyone dismisses? They're actually hiding specific patterns that can predict autoimmune flares months before symptoms hit. Hali breaks down the exact functional ranges for neutrophils, lymphocytes, and monocytes that reveal bacterial loads, viral activity, and chronic infections like EBV. This isn't about ordering expensive specialty tests - the CBC with differential is available anywhere and costs almost nothing. If you've been told your labs are normal but you still feel terrible, this episode will give you the tools to have empowered conversations with your healthcare team.For the full show notes, links and transcript visit inspiredliving.show/207

I've watched it happen over and over… high-achieving women who appear to have it all together while their bodies are quietly screaming for help through autoimmune symptoms. My guest Tori Jenae, a trauma-informed coach with multiple psychology degrees, reveals why the very traits we think make us "good" might actually be making us sick. She breaks down how people-pleasing, perfectionism, and over-functioning create chronic stress that literally changes our biology. Tori shares her powerful framework of three consciousness levels for healing and explains why your immune system might be the protective mother you never had. If you're tired of managing symptoms without addressing root causes, this episode offers a roadmap for healing that goes far beyond diet and supplements.For the complete show notes, links and transcript visit inspiredliving.show/206

Richard Peterson, CFM, FMP, SFP is Director of IFM at ABM Industries Supporting Waymo where he is responsible for overseeing facility management operations and is passionate about driving operational excellence, safety, and innovation. He also serves as Vice President of the IFMA Silicon Valley Chapter and Secretary for IFMA's Corporate Facilities Council with a mission is to assist FMs in navigating their career journey using leadership skills training, peer mentoring, and specialized education. Mike Petrusky asks Richard about his experiences in the profession and why he believes that knowing one's strengths and attributes is essential for success in facility management. Being a workplace leader in FM today involves a balance between the technical aspects of the job and the human element of creating spaces that foster innovation and productivity. Richard brings his personal passion for leadership development and community engagement to his career, which has resulted in his attaining IFMA credentials that have led to his professional success. Mike and Richard discuss IFMA's upcoming World Workplace conference in Minneapolis as they look forward to networking and great educational opportunities and they encourage you to grow in your facility management journey by offering the inspiration needed to be a Workplace Innovator! Connect with Richard on LinkedIn: https://www.linkedin.com/in/richard-peterson-cfm-fmp-sfp-33a526ba/ Learn more about IFMA's World Workplace: https://worldworkplace.ifma.org/ Explore the ABM website: https://www.abm.com/ Discover free resources and explore past interviews at: https://www.workplaceinnovator.com/ Learn more about Eptura™: https://eptura.com/ Connect with Mike on LinkedIn: https://www.linkedin.com/in/mikepetrusky/  

This week I'm sharing a conversation that could completely shift how you think about healing from trauma and chronic illness. My guest Lisa Erickson went from tech worker to energy healer after her own health crises showed her something profound: when we're dealing with trauma or chronic illness, we often disconnect from our bodies as a survival mechanism. But that same disconnection can block our healing.Lisa breaks down how chakras work as the organs in your energy anatomy, bridging your physical body, emotions, and spirit. What I love about her approach is how practical it is - you don't need to be "woo woo" or spend hours meditating. She shows you how to link simple energy practices to things you already do, like brushing your teeth.We dive deep into why the root chakra at your tailbone is the foundation for all healing (hint: it's connected to your immune system and adrenals), and she maps out how each energy center connects to specific body systems and healing opportunities.This isn't about bypassing medical care - it's about adding another layer of support that helps you feel safe in your body again.

Dr Mathur spent years watching patients stay stuck in symptom management until life opened her eyes to what's really possible. After her own health crisis forced her out of conventional medicine, she developed a three-pillar approach that's helped thousands of patients get off medications and feel like themselves again. We dive into her game-changing method for identifying toxins, deficiencies, and imbalances that block healing, plus the truth about bioidentical hormones and why your body's innate healing ability just needs the right support. If you've ever been told "your labs are fine" while feeling awful, this conversation will give you hope and practical next steps.For the complete show notes, links and transcript, visit inspiredliving.show/204

After 38 years as a primary care physician, Dr. Gary Sprouse noticed his stressed patients all knew they wanted less stress, but couldn't tell him where they wanted to be instead. This led him to develop his revolutionary "happy place" framework that's helping people transform their relationship with worry and anxiety. In this week's episode I dive deep into Gary's unique approach: why our greatest human skills create stress as side effects, the universal architecture of happiness, and his game-changing "shoebox method" for managing overwhelm. Gary gives us practical tools to transform worry into planning and build resilience in our anxiety-inducing modern world. As someone working with autoimmune conditions, I see how chronic stress impacts healing and how powerful it is when people learn to build their happy place.For the complete show notes, links and transcripts visit: inspiredliving.show/203

If you've been avoiding medicinal mushrooms because you're worried about immune stimulation, this conversation will change your mind. I talk with naturopathic doctor and mushroom expert Dr. Anna Sitkoff about how most medicinal mushrooms actually promote immune balance and tolerance.Anna explains how mushrooms support autoimmune healing on multiple levels: feeding beneficial gut bacteria, reducing pathogen load, and calming the nervous system. She shares which mushrooms work best for specific conditions, quality markers to look for when shopping, and why reishi is called the "mushroom of immortality."This episode opened my eyes to how these powerful healing allies can support our bodies naturally without overstimulating our already reactive immune systems.For the complete show notes and links visit inspiredliving.show/202

In this JCO Article Insights episode, Michael Hughes summarizes “International Myeloma Society and International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma" by Avet-Loiseau et al. published on June 09, 2025 along with an interview with author Dr Nikhil C. Munshi, MD. TRANSCRIPT Michael Hughes: Welcome to this episode of JCO Article Insights. This is Michael Hughes, JCO's editorial fellow. Today I am interviewing Dr. Nikhil Munshi on the “International Myeloma Society and International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma” by Avet-Loiseau et al. At the time of this recording, our guest has disclosures that will be linked in the transcript. While some patients with multiple myeloma live for decades after treatment, others exhibit refractory or rapidly relapsing disease irrespective of treatment administered. We term this “high-risk myeloma.” Multiple risk stratification systems have been created, starting with the Durie-Salmon system in 1975 and evolving with the advent of novel therapeutics and novel treatment approaches. In 2015, the Revised International Staging System (R-ISS) was introduced, which incorporated novel clinical and cytogenetic markers and remained, until recently, a mainstay of risk stratification in newly diagnosed disease. Myeloma as a field has, just in the past few years, though, undergone explosive changes. In particular, we have seen groundbreaking advances not only in treatments - the introduction of anti-CD38 agents and the advent of cellular and bispecific therapies - but also in diagnostic technology and our understanding of the genetic lesions in myeloma. This has led to the proliferation of numerous trials employing different definitions of high-risk myeloma, a burgeoning problem for patients and providers alike, and has prompted attempts to consolidate definitions and terminology. Regarding cytogenetic lesions, at least, Kaiser et al's federated meta-analysis of 24 therapeutic trials, published here in the JCO in February of 2025 and recently podcasted in an interview with associate editor Dr. Suzanne Lentzsch, posited a new cytogenetic classification system to realize a shared platform upon which we might contextualize those trial results. This article we have here by Dr. Avet-Loiseau, Dr. Munshi, and colleagues, published online in early June of this year and hot off the presses, is the definitive joint statement from the International Myeloma Society (IMS) and the International Myeloma Working Group (IMWG). What is high-risk multiple myeloma for the modern era? The IMS and IMWG Genomics Workshop was held in July 2023 and was attended by international myeloma experts, collaborating to reach consensus based on large volumes of data presented and shared. The datasets included cohorts from the Intergroupe Francophone du Myélome (IFM); the HARMONY project, comprised of multiple European academic trials; the FORTE study, findings from which solidified KRd as a viable induction regimen; the Grupo Español de Mieloma Múltiple (GEM) and the PETHEMA Foundation; the German-Speaking Myeloma Multicenter Group (GMMG); the UK-based Myeloma XI, findings from which confirmed the concept of lenalidomide maintenance; Emory 1000, a large, real-world dataset from Emory University in Atlanta; the Multiple Myeloma Research Foundation Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile (CoMMpass) dataset; and some newly diagnosed myeloma cohorts from the Mayo Clinic. Data were not pooled for analyses and were assessed individually - that is to say, with clear a priori understanding of whence the data had been gathered and for what original purposes. Consensus on topics was developed based on the preponderance of data across studies and cohorts. In terms of results, substantial revisions were made to the genomic staging of high-risk multiple myeloma, and these can be sorted into three major categories: A) alterations to the tumor suppressor gene TP53; B) translocations involving chromosome 14: t(14;16) (c-MAF overexpression), t(14;20) (MAFB overexpression), and t(4;14) (NSD2 overexpression); and C) chromosome 1 abnormalities: deletions of 1p or additional copies of 1q. In terms of category A, TP53 alterations: Deletion of 17p is present in up to 10% of patients at diagnosis and is enriched in relapsed or refractory disease. This is well-documented as a high-risk feature, but the proportion of the myeloma cells with deletion 17p actually impacts prognosis. GEM and HARMONY data analyses confirmed the use of 20% clonal cell fraction as the optimal threshold value for high-risk disease. That is to say, there must be the deletion of 17p in at least 20% of the myeloma cells on a FISH-analysis of a CD138-enriched bone marrow sample to qualify as high-risk disease. TP53 mutations can also occur. Inactivating mutations appear to have deleterious effects similar to chromosomal losses, and the biallelic loss of TP53, however it occurs, portends particularly poor prognosis. This effect is seen across Myeloma XI, CoMMpass, and IFM cohorts. Biallelic loss is rare, it appears to occur in only about 5% of patients, but next-generation sequencing is nevertheless recommended in all myeloma patients. Category B, chromosome 14 translocations: Translocation t(14;16) occurs in about 2% to 3% of patients with newly diagnosed disease. In the available data, primarily real-world IFM data, t(14;16) almost always occurs with chromosome 1 abnormalities. Translocation t(4;14) occurs in about 10% to 12% of newly diagnosed disease, but only patients with specific NSD2 alterations are, in fact, at risk of worse prognosis, which clinically appears to be about one in every three of those patients. And so together, the CoMMpass and Myeloma XI data suggest that translocation t(4;14) only in combination with deletion 1p or gain or amplification of 1q correlates with worse prognosis. Translocation t(14;20) occurs in only 2% of newly diagnosed disease. Similar to translocation t(4;14), it doesn't appear to have an effect on prognosis, except if the translocation co-occurs with chromosome 1 lesions, in which case patients do fare worse. Overall, these three translocations - t(14;16), t(4;14), and t(14;20) - should be considered high-risk only if chromosome 1 aberrations are also present. In terms of those chromosome 1 aberrations, category C, first deletions of 1p: Occurring in about 13% to 15% of newly diagnosed disease, deletion 1p eliminates critical cell checkpoints and normal apoptotic signaling. In the IFM and CoMMpass dataset analyses, biallelic deletion of 1p and monoallelic deletion of 1p co-occurring with additional copies of 1q denote high-risk. In terms of the other aberration in chromosome 1 possible in myeloma, gain or amplification of 1q: This occurs in up to 35% to 37% of newly diagnosed disease. It upregulates CKS1B, which is a cyclin-dependent kinase, and ANP32E, a histone acetyltransferase inhibitor. GEM and IFM data suggest that gain or amplification of 1q - there was no clear survival detriment to amplification - is best considered as a high-risk feature only in combination with the other risk factors as above. Now, in terms of any other criteria for high-risk disease, there remains one other item, and that has to do with tumor burden. There has been a consensus shift, really, in both the IMS and IMWG to attempt to develop a definition of high-risk disease which is based on biologic features rather than empirically observed and potentially temporally dynamic features, such as lactate dehydrogenase. Beta-2 microglobulin remains an independent high-risk indicator, but care must be taken when measuring it, as renal dysfunction can artificially inflate peripheral titers. The consensus conclusion was that a beta-2 microglobulin of at least 5.5 without renal failure should be considered high-risk but should not preclude detailed genomic profiling. So, in conclusion, the novel 2025 IMS-IMWG risk stratification system for myeloma is binary. It's either high-risk disease or standard-risk disease. It's got four criteria. Number one, deletion 17p and/or a TP53 mutation. Clonal cell fraction cut-off, remember, is 20%. Or number two, an IGH translocation - t(4;14), t(14;16), t(14;20) - with 1q gain and/or deletion of 1p. Or a monoallelic deletion of 1p with 1q additional copies or a biallelic deletion of 1p. Or a beta-2 microglobulin of at least 5.5 only when the creatinine is normal. This is a field-defining work that draws on analyses from across the world to put forward a dominant definition of high-risk disease and introduces a new era of biologically informed risk assessment in myeloma. Now, how does this change our clinical approach? FISH must be performed on CD138-enriched samples and should be performed for all patients. Next-generation sequencing should also be performed on all patients. Trials will hopefully now begin to include this novel definition of high-risk multiple myeloma. It does remain to be seen how data from novel therapeutic trials, if stratified according to this novel definition, will be interpreted. Will we find that therapies being evaluated at present have differential effects on myelomas with different genetic lesions? Other unanswered questions also exist. How do we go about integrating this into academic and then community clinical practice? How do we devise public health interventions for low-resource settings? To discuss this piece further, we welcome the esteemed Dr. Nikhil Munshi to the podcast. Dr. Munshi is a world-renowned leader in multiple myeloma and the corresponding author on this paper. As Professor of Medicine at Harvard Medical School, Director of the Multiple Myeloma Effector Cell Therapy Unit, and Director of Basic and Correlative Science at the Jerome Lipper Multiple Myeloma Center of the Dana-Farber Cancer Institute, he has presided over critical discoveries in the field.  Thank you for joining us, Dr. Munshi. Dr. Nikhil Munshi: Oh, it's my pleasure being here, Michael, to discuss this interesting and important publication. Michael Hughes: I had a few questions for you. So number one, this is a comprehensive, shall we say, monumental and wide-ranging definition for high-risk myeloma. How do you hope this will influence or impact the ways we discuss myeloma with patients in the exam room? And how do we make some of these components recommended, in particular next-generation sequencing, feasible in lower-resource settings? Dr. Nikhil Munshi: So those are two very important questions. Let's start with the first: How do we utilize this in our day-to-day patient care setting? So, as you know well, we have always tried to identify those patients who do not do so well with the current existing treatment. And for the last 30 years, what constitutes a myeloma of higher risk has continued to change with improvement in our treatment. The current definition basically centers around a quarter of the patients whose PFS is less than 2 to 3 years. And those would require some more involved therapeutic management. So that was a starting point of defining patients and the features. As we developed this consensus amongst ourselves - and it's titled as “International Myeloma Society, International Myeloma Working Group Consensus Recommendation” - this IMS-IMWG type of recommendation we have done for many years, improvising in various areas of myeloma care. Now, here, we looked at the data that was existing all across the globe, utilizing newer treatment and trying to identify that with these four-drug regimens, with transplant and some of the immunotherapy, which group of patients do not do as well. And this is where this current algorithm comes up. So before I answer your question straight, “How do we use it?” I might like to just suggest, “What are those features that we have identified?” There are four features which constitute high-risk disease in the newer definition. Those with deletion 17p with 20% clonality and/or TP53 mutation. Number two, patients with one of the translocations - t(4;14), t(14;16), or t(14;20) - co-occurring with 1q amplification or deletion 1p32. And that's a change. Previously, just the translocation was considered high-risk. Now we need a co-occurrence for it to be called high-risk. The third group is patients having biallelic deletion 1p32 or monoallelic deletion 1p32 along with 1q amplification. And finally, patients with high beta-2 microglobulin, more than or equal to 5.5 mg/dL, with normal creatinine less than 1.2 mg/dL. And the question, “How do we use this?” There are multiple areas where we incorporate high-risk features in our treatment algorithm. One of the first areas is where we would consider the induction regimen. If a patient has a high-risk disease, we would definitely consider a four-drug regimen rather than a three-drug regimen, although we are beginning to incorporate four-drug for all groups. That's one important thing. Number two, those are the patients where we do consider consolidation with transplant or maybe in the new world, considering some of the immunotherapeutic consolidation more early or more aggressively. Number three, these are the patients who get a little bit more maintenance therapy. So normally, lenalidomide might end up being our standard maintenance regimen. In patients who have high-risk disease, we incorporate either addition of daratumumab or the anti-CD38 targeting antibody and/or addition of proteasome inhibitor, either bortezomib or carfilzomib. So you would have multi-drug maintenance therapy in these patients. And in high-risk patients, we follow them with maintenance longer periods of time. One very critically important point to keep in mind is that to get the better outcome in high-risk disease, we must try to get them into MRD negativity because there is clear data that patients who do achieve MRD negativity, despite having high-risk disease, have a much superior outcome. They become near to standard-risk disease. And so, in high-risk patients, I would try to do whatever various options I have to try and get them into MRD-negative status. And when these patients relapse, we do not wait for the classic progression criteria to be met before we intervene. We would propose and suggest that we intervene earlier before the disease really blasts off. And so there are a number of areas in our setting where this high-risk definition will help us intervene appropriately and also with appropriate aggressiveness to achieve better outcome, to make this similar to standard-risk disease. Michael Hughes: Thank you, Dr. Munshi. And thoughts on how to really integrate this not only into academic centers but also lower-resource settings? Dr. Nikhil Munshi: So that's a very important question, Michael. And when we were developing this consensus, we were very cognizant of that fact. So wherever available, I think we are recommending that over a period of next 2, 3, 5 years, we should begin to switch over to sequencing-based methods because two components of this definition, one is TP53 mutation, which we cannot do without sequencing, and also reliably detecting deletion 1p requires sequencing-based method. So in the low-resource countries - and there are many in this world, and also even in our own country, patients may not be able to afford it - the older method with FISH or similar such technology, which is more affordable, is also acceptable for current time. They may miss a very small number of patients, maybe 2% to 3%, where these finer changes are not picked up, but a majority of this would be captured by them. So the current practice might still be applicable with some limitation in those patient populations, and that's what we would recommend. What is happening, fortunately, is that actually sequencing-based method is becoming cheaper. And in many centers, it is cheaper to do the sequencing rather than to do the FISH analysis. And so my hope is that even in low-resource centers, sequencing might be more economical in the end. It's, I think, the access to technology, which is a little bit limited currently, but it's hopefully becoming available soon. Michael Hughes: Thank you, Dr. Munshi. And staying for a minute and looking at the multiple myeloma subsets which might be missed by this really still very broad-ranging high-risk definition, at least by prior risk stratification systems, right, there is this group of patients who have standard-risk cytogenetics by R-ISS or R2-ISS, but they have primary refractory disease or they relapse early. We call these, as you are well aware, functionally high-risk disease. What proportion of previously FHR, functionally high-risk, myeloma patients do you expect to be captured by this novel definition? Dr. Nikhil Munshi: So I think the newer definition - and we can look at it both ways, but the newer definition should capture most of the functionally high-risk definition. To put it differently, Michael, there are patients who we know are, as you mentioned, functionally high-risk. Those are the patients who might have plasma cell leukemia, those who might have extramedullary disease, those who might not respond to our four-drug induction. If you don't respond to the four-drug induction, almost by definition, they are high-risk. However, a majority of them have one of the abnormalities that we are describing here. There would be a very small proportion which may not have. And if they do not have, we know one of the important components of this definition here is also that the genome, we know, keeps on evolving. So there may be a very small clone with the high-risk feature which was not obvious in the beginning. Following treatments or following relapse, that clone predominates, and now the patient's disease becomes high-risk.  So the definition would incorporate or would capture these functional high-risk patients, but as you said, in countries where resources are not available, using this functional high-risk would also be helpful and advantageous. Sometimes LDH ends up being a high-risk. In our studies, LDH has not come out to be high-risk anymore because the features we are describing captures most of those patients, but those alternatives, older, can still be considered if other newer techniques are not available. Michael Hughes: Got you. And in terms of these older definitions, yes, that incorporate tumor burden, these empirical observations about how myeloma presents, do you foresee any additional tumor burden indicators being added to future definitions of high-risk disease? Or do you instead see this particular definition as a major waypoint on the journey towards a fully biologically grounded definition of high-risk disease? Dr. Nikhil Munshi: I think your second part is what is going to happen. I think the tumor burden-related definition is being now replaced by the biological or genomic-based definition. And I think at some point, it will be quite fully replaced. One component not here, and it is because one thing, we don't have enough data; number two, we don't know how it will pan out, is also the influence of the microenvironment on the risk definition. For example, the immune system, the immune function, etc. But not enough data exists to suggest how it would change the current definition. So in future, would a definition be totally genomic or it could be more integrative? And my personal guess is that it would be more integrative and that some immune features might come into the picture, especially now that we are using immune-based therapy as a very important component of treatment - CAR T-cells, bispecific, and antibody-based treatments. What role the immune system plays in either supporting tumor or what role suppression of the anti-tumor immunity plays? They all will be important how patient outcomes end up being, and which in turn could translate into how patient's risk stratification might happen. So I think the older tumor burden-related definitions probably will become things of the past. What we have currently proposed and consensus developed is the new path forward, and over time, some microenvironmental influences, if defined and found to be important, may get some more incorporation if it compares favorably with the genomic features. Michael Hughes: Thank you, Dr. Munshi for that enlightening response.  To conclude the podcast, I'd like to look to the future and to the immediate future, what are the next steps for high-risk disease definition between now and discussing an integrated genomic-microenvironment-based definition? Will we see attempts to refine? Will we see a multi-level system, things like this? Dr. Nikhil Munshi: Yeah, so I think the current definition will be here to stay for the next 10 years or so. I think this has been developed using a large amount of data, so we do believe that this will remain fine. It has been validated now within the last six months by a few of the other studies. So there won't be a quick change. But we will try to, all of us will try to innovate. And as you very rightly bring up, the areas of research would include looking at the expression or transcriptomic component. Does that matter? And we do believe a small number of patients will have transcriptomic changes, not looked at the DNA changes, and may play a role. There are newer components, so long non-coding RNA, for example, is going to be an important component to look at, how it impacts the disease outcome, etc. There are also some of the proteomic-related changes which may become important in our studies. And then as we discussed, microenvironment and immunological changes. So these are the future areas of ongoing research where we all should collect data, and then in the next 5 to 10 years, we'll have another group meeting to see has anything changed or any of the features have become more important.  Most of the time, some of the older features are lost because they are not as critically high-risk, and the newer features come in. And so the historical background for just one second, there was a time when chromosome 13 was considered a high-risk disease. We now don't even mention it because it's not high-risk. The newer treatments have improved the outcome. t(4;14) used to be a high-risk disease. Now by itself today, in this definition by itself is not; it needs to be with something else. And so I think this is a great sign of progress. As we improve the treatment and outcomes, some of the features will become less important, new features will come up, and we'll need to keep on evolving with time and with technology and make it better for patients. Michael Hughes: Thank you so much, Dr. Munshi, for your wisdom, for your sagacity, for your historical perspective as well.  Thank you for listening to JCO Article Insights. Please come back for more interviews and article summaries. And be sure to leave us a rating and review so others can find our show. For more podcasts and episodes from ASCO, please visit asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  

In this episode, Einat Shinar and I dig into why sleep is the game changer for women's health—especially when it comes to weight, hormones, and inflammation. We break down how poor sleep throws off your hunger hormones like ghrelin and leptin, making it harder to control cravings and lose weight. Einat shares simple, science-backed habits to reset your cortisol and circadian rhythm, like morning sunlight and mindful eating with protein pacing. We also dive into sleep challenges during perimenopause and menopause, plus a clever mental trick called “cognitive shuffling” to help you fall back asleep quickly. If you're ready to stop struggling with sleep and start supporting your hormones and wellness, this episode is for you.

In this episode, we sit down with Franck Delpal, Director of the Mastère Spécialisé in Management of Fashion and Luxury at IFM and an expert in fashion economics. As the luxury sector enters a new industrial age, marked by consolidation across every level, from subcontractors and service providers to the major brands themselves, Franck Delpal breaks down the driving forces behind this shift. He explains why luxury giants are embracing vertical integration, and what this means for independent artisans, emerging designers, and the traditional values of craftsmanship. Finally, we discuss how this evolving landscape is redefining what luxury and craftsmanship mean, shaping the future of the industry.

In this powerful episode of the Tick Boot Camp Podcast, we welcome Dr. Diana Stafford, a conventionally trained MD turned functional medicine expert. Dr. Diana shares her personal and clinical journey into treating chronic illness, mold toxicity, Candida overgrowth, and Lyme disease using a science-based, root-cause approach. Learn how she helps patients reclaim their health through gut healing, vagus nerve support, mold detox protocols, and functional diagnostics not typically covered by traditional medicine.

In this episode, I sit down with Bracha Goetz, an inspiring children's author and Harvard graduate, who shares her journey from feeling empty despite outward success to discovering the life-changing power of gratitude. We dive deep into the reasons behind the relentless search for fulfillment and how society often gets success all wrong. Bracha introduces us to her unique "pleasure ladder," revealing how gratitude can transform our everyday experiences and connect us to something greater. You'll walk away with practical tips on how to cultivate gratitude in your life, which can lead to real joy and purpose—even amidst struggles. If you've ever felt that something was missing, this conversation is for you. Tune in and discover how to start filling your life with joy and gratitude today!

Do you have multiple sclerosis in your family history? Have you been recently diagnosed—or just want to lower your risk of this neurodegenerative autoimmune condition? Then this episode is for you. Dr. Terry Wahls returns to the show to help us connect the dots between MS, menopause, and midlife health. A former athlete turned wheelchair-bound physician, Dr. Wahls reversed her own secondary progressive MS using a radical diet and lifestyle protocol—and now she's teaching others to do the same. We cover: A refresher on what MS is (and why it matters more in midlife) The lifestyle non-negotiables Dr. Wahls uses to keep her MS in remission The overlap between menopause and MS symptoms—and how to tell the difference Why MS affects women 2–3 times more than men How the menopause transition can accelerate MS progression Brain health hacks and supplements to protect cognition in perimenopause and beyond What most doctors still get wrong about Hashimoto's, MS, and other autoimmune conditions in women Why strength, resilience, and radical healing are possible—even in your 60s and beyond Dr. Wahls is an Institute for Functional Medicine Certified Practitioner, author, and clinical researcher specializing in multiple sclerosis. She was awarded the IFM's Linus Pauling Award for her groundbreaking work in patient care and advocacy. Diagnosed with secondary progressive MS and once confined to a tilt-recline wheelchair, Dr. Wahls used diet and lifestyle changes to transform her health. Her Wahls Protocol is now used by thousands of patients worldwide to treat chronic autoimmune and neurological conditions. Books by Dr. Wahls: The Wahls Protocol The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions The Wahls Protocol Cooking for Life Past Episode: https://youtu.be/47M0_GlUkD0?si=6PKl391i9_CUKpNY Learn more about her trials at terrywahls.com/trials Contact Dr. Terry Wahls Website: https://terrywahls.com/ Twitter: https://twitter.com/terrywahls  Facebook: https://www.facebook.com/TerryWahls/  Instagram: https://www.instagram.com/drterrywahls/  YouTube: https://youtube.com/c/terrywahlsmd Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here. Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050 Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before August 1, 2025 to win a free set of SUJI targeted compression bands! 10% off with code ZORA at trysuji.com https://www.trysuji.com/?ref=ZORA   Join the Hack My Age community on: Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠   

In this episode, I chat with Dr. Bill Rawls, a physician with 40 years of experience who shifted his focus to herbal therapy after facing chronic illness himself. Bill shares his inspiring wellness journey from traditional medicine to discovering the healing potential of herbs, especially for chronic diseases like Lyme disease. We delve into the five stress factors affecting cellular health—nutritional, toxic, and physical stress, as well as the importance of downtime and microbial influences. Bill explains how herbs can serve as cell protectants, promoting recovery without the side effects associated with pharmaceuticals. If you're looking to understand how herbs can play a crucial role in your healing journey, this episode is packed with valuable insights!

In this episode, I chat with Dr. Eric Osansky, a chiropractor and functional medicine practitioner, about Graves' disease, a condition often overshadowed by Hashimoto's thyroiditis. We break down the key differences between these two autoimmune thyroid disorders, from symptoms like weight loss and hyperactivity in Graves' to the fatigue and weight gain associated with Hashimoto's. Dr. Osansky shares how stress can exacerbate autoimmune conditions and why managing stress is crucial for recovery. We also explore natural approaches to treatment, including dietary changes and herbal supplements. Plus, he emphasizes the importance of identifying personal triggers that may impact thyroid health. Whether you're navigating thyroid issues or simply seeking more knowledge, this episode equips you with practical insights and tools for your healing journey.

In today's episode, I sit down with Dr. Lisa Grant, a double board-certified oriental medicine doctor with a focus on fertility, to explore the often-overlooked connection between autoimmune thyroid disease and fertility. Dr. Grant shares her personal journey that led her to this field and dives into the impact of Hashimoto's on fertility. We discuss the importance of comprehensive thyroid testing beyond just TSH levels and reveal one non-negotiable lifestyle change for those with Hashimoto's: going gluten-free. With practical insights and advice, this episode is packed with valuable information for anyone navigating the complexities of autoimmune conditions and fertility. If you or someone you know is on this journey, this conversation could be a game-changer. Join us for a dose of empowerment and clarity!

In this episode, I sit down with Dr. Emily Kiberd, a chiropractor and creator of the Thyroid Strong workout program tailored for women with Hashimoto's. We dive into her personal journey of navigating fatigue and autoimmune struggles, and why traditional workouts often miss the mark for those with autoimmune conditions. Dr. Kiberd shares her transition from cardio-heavy routines to the benefits of resistance training, explaining how muscle engagement can significantly impact hormone health and inflammation. We explore practical strategies to optimize workouts, focusing on the essential "seven" movements, the importance of proper form, and the critical role nutrition plays in muscle health. Plus, Dr. Kiberd emphasizes that you don't need to push yourself to exhaustion to see results. If you're seeking a smarter approach to exercise that supports your unique health needs, this episode is for you!

In this episode of the Functional Nurse Podcast, Brigitte Sager DNP shares her insights from the annual international conference for the Institute for Functional Medicine (AIC). She discusses the themes that emerged during the conference, including the importance of connection and purpose in healthcare, the role of technology in patient care, and the significance of nutrition and group medical visits. Brigitte emphasizes the need for research to validate functional medicine practices and explores future directions for functional nursing. IFM 2026 AIC: https://www.ifm.org/aic Catalyzing and Promoting Functional Medicine Research: https://www.ifm.org/about/research  

In this episode, I sit down with Dr. Anshul Gupta, a leading expert in Hashimoto's disease, to discuss his own health journey and the innovative approaches he's developed for managing this condition. We dig into the complexities of Hashimoto's, differentiating it from simple hypothyroidism, and explore the systemic issues that often get overlooked in traditional medicine. Dr. Gupta outlines his three-step process designed to target common symptoms like fatigue, brain fog, and weight gain, emphasizing the importance of identifying triggers, restoring mitochondrial health, and detoxification. Plus, he shares his top tips for nutritious breakfast smoothies that set the stage for a healthier day. Whether you're faced with autoimmune challenges or just looking to optimize your health, this conversation is packed with insights you won't want to miss!

Join me in this episode as I chat with Maria Malec, a lifestyle and wellness architect whose insights will challenge your perspectives on health. We dive into her personal journey—a mother faced with family health issues—and how it sparked her passion for holistic wellness. Maria emphasizes the power of a positive mindset and daily choices, illustrating how small shifts can lead to significant health outcomes. We discuss the importance of being vigilant with what we consume, from food to personal care products. With practical tips on establishing routines and systems at home, Maria introduces the concept of "passive wellness," where making informed choices transforms health into a seamless aspect of life. If you're ready to take control of your health journey, this episode is for you!

This episode is filled with information on intentional trends within a variety of industries yet with a special focus on the culinary industry. Cécile talks to us about how the the trend forecasting industry has changed with the current speed of information reaching us and how this has resulted more in trend provocation whereas there is a great need for trend curation to truly help out businesses in finding answers in a difficult economical climate. Cécile Poignant is French, born and raised in Paris. She is a futurist specializing in contemporary lifestyles for the past 35 years. Her expertise lies in detecting weak signals and connecting the dots to anticipate major future shifts. She has worked with international brands such as Nissan, Swatch, Philips, L'Oréal, and P&G. Always on the lookout, she observes and deciphers emerging needs and evolving behaviors. Cécile is also actively involved in international conferences and frequently conducts workshops for professionals. She loves teaching and sharing her insights at various institutions, including IFM, ENSAD, and the American University of Paris.Her greatest passion is curiosity—she is constantly seeking to better understand the world around her. You'll often find her sipping an excellent Japanese green tea, savoring high-quality dark chocolate, or immersed in a book. Nature is her ultimate source of rejuvenation; in another life, she might have been a landscape designer.Support the showThank you for listening! Follow us through our website or social media!https://www.thecolorauthority.com/podcasthttps://www.instagram.com/the_color_authority_/https://www.linkedin.com/company/78120219/admin/

In this episode, I'm excited to welcome back Amy Stark, a former science teacher who has transformed into a powerful energy healer and author of "Bridging the Divide." Together, we delve into Amy's journey from the classroom to the healing space, uncovering how her unique blend of science and spirituality empowers individuals to navigate their own paths to transformation.We discuss the importance of emotional healing, practical tools like Emotional Freedom Techniques (EFT), and strategies to calm the nervous system through mindfulness and connection with nature. Whether you're looking for quick nervous system hacks or deep emotional insights, this conversation is packed with actionable takeaways to support your healing journey. Tune in to discover how to bridge the gap between science and spirit in your own life!For the complete show notes and links visit inspiredliving.show/193

Kalea Wattles, ND, IFMCP, is a naturopathic physician and functional medicine practitioner specializing in fertility optimization. Currently serving as the Clinical Special Projects Manager at The Institute for Functional Medicine, where she has been on staff since 2017, she is committed to the advancement of the field through research and education. She is the host of IFM's podcast Pathways to Well-Being. Dr. Wattles earned her doctorate in naturopathic medicine from Bastyr University, where she developed a keen interest in functional medicine. She went on to receive additional training from The Institute for Functional Medicine, where she further honed her skills in a root-cause, science-based, body-systems approach to healthcare.   In this episode of Conversations For Health, we explore how Dr. Kalea applies a functional medicine lens to fertility, highlighting the clinical relevance of mitochondrial health, oxidative stress, inflammaging, and more when it comes to female and male fertility. We discuss the narrative of the fertility cliff, how to assess diminished ovarian reserve even in patients in their 20s, and how to interpret AMH values in context. Our conversation is filled with actionable insights into preconception care protocols, fertility focus, lab interpretation, and how to personalize support for patients preparing for IVF or egg freezing.   I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.   Episode Resources: Dr. Kalea Wattles - https://drkaleawattles.com/ Design for Health Resources: Designs for Health - https://www.designsforhealth.com/ Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/ Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education The Designs for Health Podcast is produced in partnership with Podfly Productions. Chapters: 00:00 Intro. 02:02 Dr. Kalea is delighted about the current headlines about fertility into the 40s. 03:40 Dr. Kalea's journey into motherhood aligned with her professional focus. 06:50 AMH is the top trending biomarker in ovarian reserve. 11:41 Markers to consider in relation to oxidative stress and inflammation. 16:02 Top tier oxidative stress markers, including 8-OHdG and F2-IsoP. 18:54 The importance of mitochondrial health in ovarian health, egg quality and sperm. 23:50 DNA fragmentation and other potential findings from a semen analysis. 27:00 Shifts in the fertility conversation in recent years. 31:01 CoQ10 and melatonin recommendations that Dr. Kalea implements with her patients. 37:09 The role of glutathione in protecting against oxidative stress. 39:50 Dr. Kalea's personal experience with ovarian age testing. 43:05 Cycle Day 3 hormone measurements, including DHEA sulfate and prolactin. 49:32 Diet, environment, and other major factors in diminished ovarian reserve. 53:01 Redefining unexplained infertility. 55:06 Androgens and the impacts on eggs. 57:11 Ideal DHEA and testosterone levels. 1:00:05 The vaginal microbiome, gut health, and urea plasma. 1:03:10 Dr. Kalea's favorite personal supplements, favorite health practices, and the maternal fertility limits that she has changed her mind about.

Episode Summary:   In this eye-opening episode, we dive deep into the often-overlooked cornerstone of women's health: the cardiovascular system. Join host Dr. Robyn Benson for a powerful conversation with Andie Crosby, President of Calroy Health Sciences, as they expose why your heart—and more specifically, your blood vessels—should be the first place you look when it comes to living a longer, more vibrant life.   Guest Bio:   Andie Crosby has over 30 years' marketing and business development experience working with iconic brands such as Nike, Apple, Gap, Proctor & Gamble and magazines such as Rolling Stone, Glamour, and Vanity Fair. In 2010, her personal interest in health and wellness converged with an opportunity to build and lead the first marketing team at The Institute for Functional Medicine (IFM). She was the driving force behind a 13x increase in the number of clinicians trained by IFM and a resulting surge in awareness and demand for functional medicine amongst both patients and practitioners. She went on to run the Strategic Partnerships and Innovations team working across the ecosystem to create and nurture alliances to further the adoption of functional medicine.   TOP QUOTE                                                                                      “Vascular Health Is Foundational Health. Every organ and system in your body relies upon the oxygen, nutrients, and other molecules delivered by your vascular system. Since vascular health underpins overall health, taking care of your vascular health can change your life.”   ---Andie Crosby President of Calroy Health Sciences     Key Takeaways:   ·      Why cardiovascular health is the #1 longevity lever for women—and why it's so often ignored until it's too late ·      The critical role of the endothelial glycocalyx—a microscopic, life-sustaining structure that's ground zero for your vascular integrity, inflammation response, and nutrient delivery ·      How nitric oxide supports energy, sexual vitality, and even skin radiance—and what damages your ability to produce it naturally ·      Simple, science-backed strategies to support heart health proactively, not reactively ·      This is the conversation every woman needs to hear—whether you're optimizing for performance, preventing disease, or simply refusing to age on autopilot.   Resources for a Younger Lifestyle: From now through the end of the year, YOUNGER podcast listeners will get 10% off their order of Arterosil HP for glycocalyx support and Vascanox HP for blood flow support PLUS a free bag of oral microbiome gum for happy smiles and healthy hearts.       The Special Offer Price and the Original Price (do not include for Free Gift offers): $142 special offer; $187 original price plus free gum The link to your Special Offer item for Sale: http://calroy.com/drrobyn   For more YOUNGER Podcast Episodes: https://robynbenson.com/podcasts/   Quotes:   “Your vascular system is the foundation of your overall health. There are 60,000 miles of blood vessels in your body. They supply oxygen and essential nutrients to every organ in your body and carry away toxic waste. If you're looking for a long and healthy life, taking care of your vascular system must be a top priority.”   “Many women are recognizing the importance of physical activity for their cardiovascular health.” “Menopausal Women have greater challenges to maintaining their vascular health due to hormonal shifts.”   “Women preparing for the menopause transition, who would like to live a preventative lifestyle consider eating an anti-inflammatory diet, reducing insulin resistance and visceral fat, incorporating strength, aerobic, and flexibility training as rotation in their weekly exercises, and investing in sleep comfort.”    "The endothelial glycocalyx is really one of the most important and intensely researched areas in human health in years." ---Dr. Kara Fitzgerald    

Join me in this episode as I chat with Dr. Aly Cohen, an award-winning physician and leading voice in environmental health. We're diving into her impactful book, "Detoxify," which offers practical tips for reducing toxin exposure in our daily lives. You'll hear about Aly's own journey sparked by her dog's illness, leading her to discover the significant gaps in consumer product safety. We'll discuss how everyday toxins can harm our health, the importance of dietary choices in detoxification, and how making small changes—like swapping out cleaning products—can lead to big improvements. Plus, we'll touch on the need for advocacy in healthcare. Tune in to learn how to take control of your health, one manageable step at a time!For the complete show notes and links visit inspiredliving.show/192

This week, I'm thrilled to chat with Tiffany Kaloustian, a functional medicine practitioner who has navigated her own journey with systemic lupus. We delve into her early struggles with symptoms, the fight for a proper diagnosis, and the vital role of patient advocacy. Tiffany shares how autoimmunity impacted her mental health and led her to discover the transformative power of functional medicine. We talk about the importance of embracing all emotions in the healing process, and surprisingly, the role that dance played in her journey. Plus, she gives us insights about developing resilience and the mindset shifts needed to thrive with chronic illness. Whether you're on your own health journey or just curious, this conversation is packed with inspiration and practical takeaways. Don't miss it!For the complete show notes and links visit inspiredliving.show/191

Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below. Listen to the full episode. Dr. Grace Liu PharmD is an IFM-trained functional medicine practitioner and founder of The Gut Institute. She is a clinical pharmacist with a doctorate in practice for 20+ years and specializes in complex disease management. Dr. Liu consults and helps clients gain optimal performance through rebuilding the microbiome after damage from modern living. You can find her at thegutinstitute.com.  In this episode: How gut health affects hormone balance and weight loss. Why the SARS-CoV-2 virus and certain vaccines could be influencing gut health. How gut bacteria can influence testosterone levels. Why addressing the root cause of inflammation can positively impact both men and women. Harmful effects of low fiber diets on gut health. The pivotal role of peptides in achieving health goals. Why addressing the mental component of weight loss is crucial. How emotional trauma can contribute to self-sabotage and weight gain. The concept of microdosing and how GLP-1 agonists can bolster gut health and weight loss. The connection between gut health and hormone health. How parasites and Candida can contribute to premature aging. The role of good flora in the gut. The importance of dietary fiber and prebiotics in supporting gut health. How synthetic peptides can potentially help in healing and reaching health goals. Effects tat emotional trauma can have on weight gain. The power of biohacking tools, such as peptides, to help people lose weight.   Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

In this eye-opening fertility episode, Dr. Wendy Trubow, MD, IFMCP, peels back the curtain on one of the most misunderstood issues in reproductive health: the toxic load we carry — and how it's silently sabotaging fertility in both men and women.Wendie Trubow, MD, MBA,IFM certified practitioner, is passionate about helping women optimize their health and lives as a functional medicine gynecologist. Through her struggles with mold and metal toxicity, Celiac disease, and other health issues, Trubow has developed a deep sense of compassion and expertise for what her patients are facing. She is the co-author of Dirty Girl: Ditch the Toxins, Look Great, and Feel Freaking Amazing and has been regularly featured in MindBodyGreen.This conversation isn't just for those trying to conceive — it's for anyone who wants to understand how the environment, food system, stress, and personal care industry are all intersecting with the skyrocketing rates of infertility, autoimmune diseases, metabolic disorders, and hormonal imbalance.Key InsightsWhy infertility is a symptom — not your identityHow inflammation blocks conception, even when all your tests look "normal"Why sperm counts are plummeting — and what that means for the futureHow to detox SAFELY before pregnancy — and what to avoid once you're pregnantWhy managing stress is just as important as managing toxins"You can't detox if you're stressed out — because stress turns OFF your detox pathways."The Three Toxic Buckets That Fuel InflammationWhat you put IN your bodyFood, plastics, pesticidesWhat you put ON your bodyMakeup, lotions, laundry detergentsWhat surrounds youAir, water, EMFs in your home + environmentDr. Wendy's JourneyDr. Wendy shares her personal story of toxic overload — despite doing "everything right" — and how she turned it into a roadmap for healing in her bestselling book "Dirty Girl."Recommended Clean Products & BrandsBeautyBeautyCounterBurt's BeesMineral FusionCleaning & LaundryAspen Clean (EWG Certified)Water FiltersBerkeyAquasanaReverse Osmosis systemsAir FiltersIQ Air ATEM (for cars)Air DoctorMolekuleResources