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If you've been avoiding medicinal mushrooms because you're worried about immune stimulation, this conversation will change your mind. I talk with naturopathic doctor and mushroom expert Dr. Anna Sitkoff about how most medicinal mushrooms actually promote immune balance and tolerance.Anna explains how mushrooms support autoimmune healing on multiple levels: feeding beneficial gut bacteria, reducing pathogen load, and calming the nervous system. She shares which mushrooms work best for specific conditions, quality markers to look for when shopping, and why reishi is called the "mushroom of immortality."This episode opened my eyes to how these powerful healing allies can support our bodies naturally without overstimulating our already reactive immune systems.For the complete show notes and links visit inspiredliving.show/202
In this JCO Article Insights episode, Michael Hughes summarizes “International Myeloma Society and International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma" by Avet-Loiseau et al. published on June 09, 2025 along with an interview with author Dr Nikhil C. Munshi, MD. TRANSCRIPT Michael Hughes: Welcome to this episode of JCO Article Insights. This is Michael Hughes, JCO's editorial fellow. Today I am interviewing Dr. Nikhil Munshi on the “International Myeloma Society and International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma” by Avet-Loiseau et al. At the time of this recording, our guest has disclosures that will be linked in the transcript. While some patients with multiple myeloma live for decades after treatment, others exhibit refractory or rapidly relapsing disease irrespective of treatment administered. We term this “high-risk myeloma.” Multiple risk stratification systems have been created, starting with the Durie-Salmon system in 1975 and evolving with the advent of novel therapeutics and novel treatment approaches. In 2015, the Revised International Staging System (R-ISS) was introduced, which incorporated novel clinical and cytogenetic markers and remained, until recently, a mainstay of risk stratification in newly diagnosed disease. Myeloma as a field has, just in the past few years, though, undergone explosive changes. In particular, we have seen groundbreaking advances not only in treatments - the introduction of anti-CD38 agents and the advent of cellular and bispecific therapies - but also in diagnostic technology and our understanding of the genetic lesions in myeloma. This has led to the proliferation of numerous trials employing different definitions of high-risk myeloma, a burgeoning problem for patients and providers alike, and has prompted attempts to consolidate definitions and terminology. Regarding cytogenetic lesions, at least, Kaiser et al's federated meta-analysis of 24 therapeutic trials, published here in the JCO in February of 2025 and recently podcasted in an interview with associate editor Dr. Suzanne Lentzsch, posited a new cytogenetic classification system to realize a shared platform upon which we might contextualize those trial results. This article we have here by Dr. Avet-Loiseau, Dr. Munshi, and colleagues, published online in early June of this year and hot off the presses, is the definitive joint statement from the International Myeloma Society (IMS) and the International Myeloma Working Group (IMWG). What is high-risk multiple myeloma for the modern era? The IMS and IMWG Genomics Workshop was held in July 2023 and was attended by international myeloma experts, collaborating to reach consensus based on large volumes of data presented and shared. The datasets included cohorts from the Intergroupe Francophone du Myélome (IFM); the HARMONY project, comprised of multiple European academic trials; the FORTE study, findings from which solidified KRd as a viable induction regimen; the Grupo Español de Mieloma Múltiple (GEM) and the PETHEMA Foundation; the German-Speaking Myeloma Multicenter Group (GMMG); the UK-based Myeloma XI, findings from which confirmed the concept of lenalidomide maintenance; Emory 1000, a large, real-world dataset from Emory University in Atlanta; the Multiple Myeloma Research Foundation Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile (CoMMpass) dataset; and some newly diagnosed myeloma cohorts from the Mayo Clinic. Data were not pooled for analyses and were assessed individually - that is to say, with clear a priori understanding of whence the data had been gathered and for what original purposes. Consensus on topics was developed based on the preponderance of data across studies and cohorts. In terms of results, substantial revisions were made to the genomic staging of high-risk multiple myeloma, and these can be sorted into three major categories: A) alterations to the tumor suppressor gene TP53; B) translocations involving chromosome 14: t(14;16) (c-MAF overexpression), t(14;20) (MAFB overexpression), and t(4;14) (NSD2 overexpression); and C) chromosome 1 abnormalities: deletions of 1p or additional copies of 1q. In terms of category A, TP53 alterations: Deletion of 17p is present in up to 10% of patients at diagnosis and is enriched in relapsed or refractory disease. This is well-documented as a high-risk feature, but the proportion of the myeloma cells with deletion 17p actually impacts prognosis. GEM and HARMONY data analyses confirmed the use of 20% clonal cell fraction as the optimal threshold value for high-risk disease. That is to say, there must be the deletion of 17p in at least 20% of the myeloma cells on a FISH-analysis of a CD138-enriched bone marrow sample to qualify as high-risk disease. TP53 mutations can also occur. Inactivating mutations appear to have deleterious effects similar to chromosomal losses, and the biallelic loss of TP53, however it occurs, portends particularly poor prognosis. This effect is seen across Myeloma XI, CoMMpass, and IFM cohorts. Biallelic loss is rare, it appears to occur in only about 5% of patients, but next-generation sequencing is nevertheless recommended in all myeloma patients. Category B, chromosome 14 translocations: Translocation t(14;16) occurs in about 2% to 3% of patients with newly diagnosed disease. In the available data, primarily real-world IFM data, t(14;16) almost always occurs with chromosome 1 abnormalities. Translocation t(4;14) occurs in about 10% to 12% of newly diagnosed disease, but only patients with specific NSD2 alterations are, in fact, at risk of worse prognosis, which clinically appears to be about one in every three of those patients. And so together, the CoMMpass and Myeloma XI data suggest that translocation t(4;14) only in combination with deletion 1p or gain or amplification of 1q correlates with worse prognosis. Translocation t(14;20) occurs in only 2% of newly diagnosed disease. Similar to translocation t(4;14), it doesn't appear to have an effect on prognosis, except if the translocation co-occurs with chromosome 1 lesions, in which case patients do fare worse. Overall, these three translocations - t(14;16), t(4;14), and t(14;20) - should be considered high-risk only if chromosome 1 aberrations are also present. In terms of those chromosome 1 aberrations, category C, first deletions of 1p: Occurring in about 13% to 15% of newly diagnosed disease, deletion 1p eliminates critical cell checkpoints and normal apoptotic signaling. In the IFM and CoMMpass dataset analyses, biallelic deletion of 1p and monoallelic deletion of 1p co-occurring with additional copies of 1q denote high-risk. In terms of the other aberration in chromosome 1 possible in myeloma, gain or amplification of 1q: This occurs in up to 35% to 37% of newly diagnosed disease. It upregulates CKS1B, which is a cyclin-dependent kinase, and ANP32E, a histone acetyltransferase inhibitor. GEM and IFM data suggest that gain or amplification of 1q - there was no clear survival detriment to amplification - is best considered as a high-risk feature only in combination with the other risk factors as above. Now, in terms of any other criteria for high-risk disease, there remains one other item, and that has to do with tumor burden. There has been a consensus shift, really, in both the IMS and IMWG to attempt to develop a definition of high-risk disease which is based on biologic features rather than empirically observed and potentially temporally dynamic features, such as lactate dehydrogenase. Beta-2 microglobulin remains an independent high-risk indicator, but care must be taken when measuring it, as renal dysfunction can artificially inflate peripheral titers. The consensus conclusion was that a beta-2 microglobulin of at least 5.5 without renal failure should be considered high-risk but should not preclude detailed genomic profiling. So, in conclusion, the novel 2025 IMS-IMWG risk stratification system for myeloma is binary. It's either high-risk disease or standard-risk disease. It's got four criteria. Number one, deletion 17p and/or a TP53 mutation. Clonal cell fraction cut-off, remember, is 20%. Or number two, an IGH translocation - t(4;14), t(14;16), t(14;20) - with 1q gain and/or deletion of 1p. Or a monoallelic deletion of 1p with 1q additional copies or a biallelic deletion of 1p. Or a beta-2 microglobulin of at least 5.5 only when the creatinine is normal. This is a field-defining work that draws on analyses from across the world to put forward a dominant definition of high-risk disease and introduces a new era of biologically informed risk assessment in myeloma. Now, how does this change our clinical approach? FISH must be performed on CD138-enriched samples and should be performed for all patients. Next-generation sequencing should also be performed on all patients. Trials will hopefully now begin to include this novel definition of high-risk multiple myeloma. It does remain to be seen how data from novel therapeutic trials, if stratified according to this novel definition, will be interpreted. Will we find that therapies being evaluated at present have differential effects on myelomas with different genetic lesions? Other unanswered questions also exist. How do we go about integrating this into academic and then community clinical practice? How do we devise public health interventions for low-resource settings? To discuss this piece further, we welcome the esteemed Dr. Nikhil Munshi to the podcast. Dr. Munshi is a world-renowned leader in multiple myeloma and the corresponding author on this paper. As Professor of Medicine at Harvard Medical School, Director of the Multiple Myeloma Effector Cell Therapy Unit, and Director of Basic and Correlative Science at the Jerome Lipper Multiple Myeloma Center of the Dana-Farber Cancer Institute, he has presided over critical discoveries in the field. Thank you for joining us, Dr. Munshi. Dr. Nikhil Munshi: Oh, it's my pleasure being here, Michael, to discuss this interesting and important publication. Michael Hughes: I had a few questions for you. So number one, this is a comprehensive, shall we say, monumental and wide-ranging definition for high-risk myeloma. How do you hope this will influence or impact the ways we discuss myeloma with patients in the exam room? And how do we make some of these components recommended, in particular next-generation sequencing, feasible in lower-resource settings? Dr. Nikhil Munshi: So those are two very important questions. Let's start with the first: How do we utilize this in our day-to-day patient care setting? So, as you know well, we have always tried to identify those patients who do not do so well with the current existing treatment. And for the last 30 years, what constitutes a myeloma of higher risk has continued to change with improvement in our treatment. The current definition basically centers around a quarter of the patients whose PFS is less than 2 to 3 years. And those would require some more involved therapeutic management. So that was a starting point of defining patients and the features. As we developed this consensus amongst ourselves - and it's titled as “International Myeloma Society, International Myeloma Working Group Consensus Recommendation” - this IMS-IMWG type of recommendation we have done for many years, improvising in various areas of myeloma care. Now, here, we looked at the data that was existing all across the globe, utilizing newer treatment and trying to identify that with these four-drug regimens, with transplant and some of the immunotherapy, which group of patients do not do as well. And this is where this current algorithm comes up. So before I answer your question straight, “How do we use it?” I might like to just suggest, “What are those features that we have identified?” There are four features which constitute high-risk disease in the newer definition. Those with deletion 17p with 20% clonality and/or TP53 mutation. Number two, patients with one of the translocations - t(4;14), t(14;16), or t(14;20) - co-occurring with 1q amplification or deletion 1p32. And that's a change. Previously, just the translocation was considered high-risk. Now we need a co-occurrence for it to be called high-risk. The third group is patients having biallelic deletion 1p32 or monoallelic deletion 1p32 along with 1q amplification. And finally, patients with high beta-2 microglobulin, more than or equal to 5.5 mg/dL, with normal creatinine less than 1.2 mg/dL. And the question, “How do we use this?” There are multiple areas where we incorporate high-risk features in our treatment algorithm. One of the first areas is where we would consider the induction regimen. If a patient has a high-risk disease, we would definitely consider a four-drug regimen rather than a three-drug regimen, although we are beginning to incorporate four-drug for all groups. That's one important thing. Number two, those are the patients where we do consider consolidation with transplant or maybe in the new world, considering some of the immunotherapeutic consolidation more early or more aggressively. Number three, these are the patients who get a little bit more maintenance therapy. So normally, lenalidomide might end up being our standard maintenance regimen. In patients who have high-risk disease, we incorporate either addition of daratumumab or the anti-CD38 targeting antibody and/or addition of proteasome inhibitor, either bortezomib or carfilzomib. So you would have multi-drug maintenance therapy in these patients. And in high-risk patients, we follow them with maintenance longer periods of time. One very critically important point to keep in mind is that to get the better outcome in high-risk disease, we must try to get them into MRD negativity because there is clear data that patients who do achieve MRD negativity, despite having high-risk disease, have a much superior outcome. They become near to standard-risk disease. And so, in high-risk patients, I would try to do whatever various options I have to try and get them into MRD-negative status. And when these patients relapse, we do not wait for the classic progression criteria to be met before we intervene. We would propose and suggest that we intervene earlier before the disease really blasts off. And so there are a number of areas in our setting where this high-risk definition will help us intervene appropriately and also with appropriate aggressiveness to achieve better outcome, to make this similar to standard-risk disease. Michael Hughes: Thank you, Dr. Munshi. And thoughts on how to really integrate this not only into academic centers but also lower-resource settings? Dr. Nikhil Munshi: So that's a very important question, Michael. And when we were developing this consensus, we were very cognizant of that fact. So wherever available, I think we are recommending that over a period of next 2, 3, 5 years, we should begin to switch over to sequencing-based methods because two components of this definition, one is TP53 mutation, which we cannot do without sequencing, and also reliably detecting deletion 1p requires sequencing-based method. So in the low-resource countries - and there are many in this world, and also even in our own country, patients may not be able to afford it - the older method with FISH or similar such technology, which is more affordable, is also acceptable for current time. They may miss a very small number of patients, maybe 2% to 3%, where these finer changes are not picked up, but a majority of this would be captured by them. So the current practice might still be applicable with some limitation in those patient populations, and that's what we would recommend. What is happening, fortunately, is that actually sequencing-based method is becoming cheaper. And in many centers, it is cheaper to do the sequencing rather than to do the FISH analysis. And so my hope is that even in low-resource centers, sequencing might be more economical in the end. It's, I think, the access to technology, which is a little bit limited currently, but it's hopefully becoming available soon. Michael Hughes: Thank you, Dr. Munshi. And staying for a minute and looking at the multiple myeloma subsets which might be missed by this really still very broad-ranging high-risk definition, at least by prior risk stratification systems, right, there is this group of patients who have standard-risk cytogenetics by R-ISS or R2-ISS, but they have primary refractory disease or they relapse early. We call these, as you are well aware, functionally high-risk disease. What proportion of previously FHR, functionally high-risk, myeloma patients do you expect to be captured by this novel definition? Dr. Nikhil Munshi: So I think the newer definition - and we can look at it both ways, but the newer definition should capture most of the functionally high-risk definition. To put it differently, Michael, there are patients who we know are, as you mentioned, functionally high-risk. Those are the patients who might have plasma cell leukemia, those who might have extramedullary disease, those who might not respond to our four-drug induction. If you don't respond to the four-drug induction, almost by definition, they are high-risk. However, a majority of them have one of the abnormalities that we are describing here. There would be a very small proportion which may not have. And if they do not have, we know one of the important components of this definition here is also that the genome, we know, keeps on evolving. So there may be a very small clone with the high-risk feature which was not obvious in the beginning. Following treatments or following relapse, that clone predominates, and now the patient's disease becomes high-risk. So the definition would incorporate or would capture these functional high-risk patients, but as you said, in countries where resources are not available, using this functional high-risk would also be helpful and advantageous. Sometimes LDH ends up being a high-risk. In our studies, LDH has not come out to be high-risk anymore because the features we are describing captures most of those patients, but those alternatives, older, can still be considered if other newer techniques are not available. Michael Hughes: Got you. And in terms of these older definitions, yes, that incorporate tumor burden, these empirical observations about how myeloma presents, do you foresee any additional tumor burden indicators being added to future definitions of high-risk disease? Or do you instead see this particular definition as a major waypoint on the journey towards a fully biologically grounded definition of high-risk disease? Dr. Nikhil Munshi: I think your second part is what is going to happen. I think the tumor burden-related definition is being now replaced by the biological or genomic-based definition. And I think at some point, it will be quite fully replaced. One component not here, and it is because one thing, we don't have enough data; number two, we don't know how it will pan out, is also the influence of the microenvironment on the risk definition. For example, the immune system, the immune function, etc. But not enough data exists to suggest how it would change the current definition. So in future, would a definition be totally genomic or it could be more integrative? And my personal guess is that it would be more integrative and that some immune features might come into the picture, especially now that we are using immune-based therapy as a very important component of treatment - CAR T-cells, bispecific, and antibody-based treatments. What role the immune system plays in either supporting tumor or what role suppression of the anti-tumor immunity plays? They all will be important how patient outcomes end up being, and which in turn could translate into how patient's risk stratification might happen. So I think the older tumor burden-related definitions probably will become things of the past. What we have currently proposed and consensus developed is the new path forward, and over time, some microenvironmental influences, if defined and found to be important, may get some more incorporation if it compares favorably with the genomic features. Michael Hughes: Thank you, Dr. Munshi for that enlightening response. To conclude the podcast, I'd like to look to the future and to the immediate future, what are the next steps for high-risk disease definition between now and discussing an integrated genomic-microenvironment-based definition? Will we see attempts to refine? Will we see a multi-level system, things like this? Dr. Nikhil Munshi: Yeah, so I think the current definition will be here to stay for the next 10 years or so. I think this has been developed using a large amount of data, so we do believe that this will remain fine. It has been validated now within the last six months by a few of the other studies. So there won't be a quick change. But we will try to, all of us will try to innovate. And as you very rightly bring up, the areas of research would include looking at the expression or transcriptomic component. Does that matter? And we do believe a small number of patients will have transcriptomic changes, not looked at the DNA changes, and may play a role. There are newer components, so long non-coding RNA, for example, is going to be an important component to look at, how it impacts the disease outcome, etc. There are also some of the proteomic-related changes which may become important in our studies. And then as we discussed, microenvironment and immunological changes. So these are the future areas of ongoing research where we all should collect data, and then in the next 5 to 10 years, we'll have another group meeting to see has anything changed or any of the features have become more important. Most of the time, some of the older features are lost because they are not as critically high-risk, and the newer features come in. And so the historical background for just one second, there was a time when chromosome 13 was considered a high-risk disease. We now don't even mention it because it's not high-risk. The newer treatments have improved the outcome. t(4;14) used to be a high-risk disease. Now by itself today, in this definition by itself is not; it needs to be with something else. And so I think this is a great sign of progress. As we improve the treatment and outcomes, some of the features will become less important, new features will come up, and we'll need to keep on evolving with time and with technology and make it better for patients. Michael Hughes: Thank you so much, Dr. Munshi, for your wisdom, for your sagacity, for your historical perspective as well. Thank you for listening to JCO Article Insights. Please come back for more interviews and article summaries. And be sure to leave us a rating and review so others can find our show. For more podcasts and episodes from ASCO, please visit asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
In this episode, Einat Shinar and I dig into why sleep is the game changer for women's health—especially when it comes to weight, hormones, and inflammation. We break down how poor sleep throws off your hunger hormones like ghrelin and leptin, making it harder to control cravings and lose weight. Einat shares simple, science-backed habits to reset your cortisol and circadian rhythm, like morning sunlight and mindful eating with protein pacing. We also dive into sleep challenges during perimenopause and menopause, plus a clever mental trick called “cognitive shuffling” to help you fall back asleep quickly. If you're ready to stop struggling with sleep and start supporting your hormones and wellness, this episode is for you.
In this episode, we sit down with Franck Delpal, Director of the Mastère Spécialisé in Management of Fashion and Luxury at IFM and an expert in fashion economics. As the luxury sector enters a new industrial age, marked by consolidation across every level, from subcontractors and service providers to the major brands themselves, Franck Delpal breaks down the driving forces behind this shift. He explains why luxury giants are embracing vertical integration, and what this means for independent artisans, emerging designers, and the traditional values of craftsmanship. Finally, we discuss how this evolving landscape is redefining what luxury and craftsmanship mean, shaping the future of the industry.
In this powerful episode of the Tick Boot Camp Podcast, we welcome Dr. Diana Stafford, a conventionally trained MD turned functional medicine expert. Dr. Diana shares her personal and clinical journey into treating chronic illness, mold toxicity, Candida overgrowth, and Lyme disease using a science-based, root-cause approach. Learn how she helps patients reclaim their health through gut healing, vagus nerve support, mold detox protocols, and functional diagnostics not typically covered by traditional medicine.
In this episode, I sit down with Bracha Goetz, an inspiring children's author and Harvard graduate, who shares her journey from feeling empty despite outward success to discovering the life-changing power of gratitude. We dive deep into the reasons behind the relentless search for fulfillment and how society often gets success all wrong. Bracha introduces us to her unique "pleasure ladder," revealing how gratitude can transform our everyday experiences and connect us to something greater. You'll walk away with practical tips on how to cultivate gratitude in your life, which can lead to real joy and purpose—even amidst struggles. If you've ever felt that something was missing, this conversation is for you. Tune in and discover how to start filling your life with joy and gratitude today!
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The Functional Nurse Podcast - Nursing in Functional Medicine
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Join me in this episode as I chat with Maria Malec, a lifestyle and wellness architect whose insights will challenge your perspectives on health. We dive into her personal journey—a mother faced with family health issues—and how it sparked her passion for holistic wellness. Maria emphasizes the power of a positive mindset and daily choices, illustrating how small shifts can lead to significant health outcomes. We discuss the importance of being vigilant with what we consume, from food to personal care products. With practical tips on establishing routines and systems at home, Maria introduces the concept of "passive wellness," where making informed choices transforms health into a seamless aspect of life. If you're ready to take control of your health journey, this episode is for you!
This episode is filled with information on intentional trends within a variety of industries yet with a special focus on the culinary industry. Cécile talks to us about how the the trend forecasting industry has changed with the current speed of information reaching us and how this has resulted more in trend provocation whereas there is a great need for trend curation to truly help out businesses in finding answers in a difficult economical climate. Cécile Poignant is French, born and raised in Paris. She is a futurist specializing in contemporary lifestyles for the past 35 years. Her expertise lies in detecting weak signals and connecting the dots to anticipate major future shifts. She has worked with international brands such as Nissan, Swatch, Philips, L'Oréal, and P&G. Always on the lookout, she observes and deciphers emerging needs and evolving behaviors. Cécile is also actively involved in international conferences and frequently conducts workshops for professionals. She loves teaching and sharing her insights at various institutions, including IFM, ENSAD, and the American University of Paris.Her greatest passion is curiosity—she is constantly seeking to better understand the world around her. You'll often find her sipping an excellent Japanese green tea, savoring high-quality dark chocolate, or immersed in a book. Nature is her ultimate source of rejuvenation; in another life, she might have been a landscape designer.Support the showThank you for listening! Follow us through our website or social media!https://www.thecolorauthority.com/podcasthttps://www.instagram.com/the_color_authority_/https://www.linkedin.com/company/78120219/admin/
In this episode, I'm excited to welcome back Amy Stark, a former science teacher who has transformed into a powerful energy healer and author of "Bridging the Divide." Together, we delve into Amy's journey from the classroom to the healing space, uncovering how her unique blend of science and spirituality empowers individuals to navigate their own paths to transformation.We discuss the importance of emotional healing, practical tools like Emotional Freedom Techniques (EFT), and strategies to calm the nervous system through mindfulness and connection with nature. Whether you're looking for quick nervous system hacks or deep emotional insights, this conversation is packed with actionable takeaways to support your healing journey. Tune in to discover how to bridge the gap between science and spirit in your own life!For the complete show notes and links visit inspiredliving.show/193
Kalea Wattles, ND, IFMCP, is a naturopathic physician and functional medicine practitioner specializing in fertility optimization. Currently serving as the Clinical Special Projects Manager at The Institute for Functional Medicine, where she has been on staff since 2017, she is committed to the advancement of the field through research and education. She is the host of IFM's podcast Pathways to Well-Being. Dr. Wattles earned her doctorate in naturopathic medicine from Bastyr University, where she developed a keen interest in functional medicine. She went on to receive additional training from The Institute for Functional Medicine, where she further honed her skills in a root-cause, science-based, body-systems approach to healthcare. In this episode of Conversations For Health, we explore how Dr. Kalea applies a functional medicine lens to fertility, highlighting the clinical relevance of mitochondrial health, oxidative stress, inflammaging, and more when it comes to female and male fertility. We discuss the narrative of the fertility cliff, how to assess diminished ovarian reserve even in patients in their 20s, and how to interpret AMH values in context. Our conversation is filled with actionable insights into preconception care protocols, fertility focus, lab interpretation, and how to personalize support for patients preparing for IVF or egg freezing. I'm your host, Evelyne Lambrecht, thank you for designing a well world with us. Episode Resources: Dr. Kalea Wattles - https://drkaleawattles.com/ Design for Health Resources: Designs for Health - https://www.designsforhealth.com/ Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/ Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education The Designs for Health Podcast is produced in partnership with Podfly Productions. Chapters: 00:00 Intro. 02:02 Dr. Kalea is delighted about the current headlines about fertility into the 40s. 03:40 Dr. Kalea's journey into motherhood aligned with her professional focus. 06:50 AMH is the top trending biomarker in ovarian reserve. 11:41 Markers to consider in relation to oxidative stress and inflammation. 16:02 Top tier oxidative stress markers, including 8-OHdG and F2-IsoP. 18:54 The importance of mitochondrial health in ovarian health, egg quality and sperm. 23:50 DNA fragmentation and other potential findings from a semen analysis. 27:00 Shifts in the fertility conversation in recent years. 31:01 CoQ10 and melatonin recommendations that Dr. Kalea implements with her patients. 37:09 The role of glutathione in protecting against oxidative stress. 39:50 Dr. Kalea's personal experience with ovarian age testing. 43:05 Cycle Day 3 hormone measurements, including DHEA sulfate and prolactin. 49:32 Diet, environment, and other major factors in diminished ovarian reserve. 53:01 Redefining unexplained infertility. 55:06 Androgens and the impacts on eggs. 57:11 Ideal DHEA and testosterone levels. 1:00:05 The vaginal microbiome, gut health, and urea plasma. 1:03:10 Dr. Kalea's favorite personal supplements, favorite health practices, and the maternal fertility limits that she has changed her mind about.
Episode Summary: In this eye-opening episode, we dive deep into the often-overlooked cornerstone of women's health: the cardiovascular system. Join host Dr. Robyn Benson for a powerful conversation with Andie Crosby, President of Calroy Health Sciences, as they expose why your heart—and more specifically, your blood vessels—should be the first place you look when it comes to living a longer, more vibrant life. Guest Bio: Andie Crosby has over 30 years' marketing and business development experience working with iconic brands such as Nike, Apple, Gap, Proctor & Gamble and magazines such as Rolling Stone, Glamour, and Vanity Fair. In 2010, her personal interest in health and wellness converged with an opportunity to build and lead the first marketing team at The Institute for Functional Medicine (IFM). She was the driving force behind a 13x increase in the number of clinicians trained by IFM and a resulting surge in awareness and demand for functional medicine amongst both patients and practitioners. She went on to run the Strategic Partnerships and Innovations team working across the ecosystem to create and nurture alliances to further the adoption of functional medicine. TOP QUOTE “Vascular Health Is Foundational Health. Every organ and system in your body relies upon the oxygen, nutrients, and other molecules delivered by your vascular system. Since vascular health underpins overall health, taking care of your vascular health can change your life.” ---Andie Crosby President of Calroy Health Sciences Key Takeaways: · Why cardiovascular health is the #1 longevity lever for women—and why it's so often ignored until it's too late · The critical role of the endothelial glycocalyx—a microscopic, life-sustaining structure that's ground zero for your vascular integrity, inflammation response, and nutrient delivery · How nitric oxide supports energy, sexual vitality, and even skin radiance—and what damages your ability to produce it naturally · Simple, science-backed strategies to support heart health proactively, not reactively · This is the conversation every woman needs to hear—whether you're optimizing for performance, preventing disease, or simply refusing to age on autopilot. Resources for a Younger Lifestyle: From now through the end of the year, YOUNGER podcast listeners will get 10% off their order of Arterosil HP for glycocalyx support and Vascanox HP for blood flow support PLUS a free bag of oral microbiome gum for happy smiles and healthy hearts. The Special Offer Price and the Original Price (do not include for Free Gift offers): $142 special offer; $187 original price plus free gum The link to your Special Offer item for Sale: http://calroy.com/drrobyn For more YOUNGER Podcast Episodes: https://robynbenson.com/podcasts/ Quotes: “Your vascular system is the foundation of your overall health. There are 60,000 miles of blood vessels in your body. They supply oxygen and essential nutrients to every organ in your body and carry away toxic waste. If you're looking for a long and healthy life, taking care of your vascular system must be a top priority.” “Many women are recognizing the importance of physical activity for their cardiovascular health.” “Menopausal Women have greater challenges to maintaining their vascular health due to hormonal shifts.” “Women preparing for the menopause transition, who would like to live a preventative lifestyle consider eating an anti-inflammatory diet, reducing insulin resistance and visceral fat, incorporating strength, aerobic, and flexibility training as rotation in their weekly exercises, and investing in sleep comfort.” "The endothelial glycocalyx is really one of the most important and intensely researched areas in human health in years." ---Dr. Kara Fitzgerald
Join me in this episode as I chat with Dr. Aly Cohen, an award-winning physician and leading voice in environmental health. We're diving into her impactful book, "Detoxify," which offers practical tips for reducing toxin exposure in our daily lives. You'll hear about Aly's own journey sparked by her dog's illness, leading her to discover the significant gaps in consumer product safety. We'll discuss how everyday toxins can harm our health, the importance of dietary choices in detoxification, and how making small changes—like swapping out cleaning products—can lead to big improvements. Plus, we'll touch on the need for advocacy in healthcare. Tune in to learn how to take control of your health, one manageable step at a time!For the complete show notes and links visit inspiredliving.show/192
This week, I'm thrilled to chat with Tiffany Kaloustian, a functional medicine practitioner who has navigated her own journey with systemic lupus. We delve into her early struggles with symptoms, the fight for a proper diagnosis, and the vital role of patient advocacy. Tiffany shares how autoimmunity impacted her mental health and led her to discover the transformative power of functional medicine. We talk about the importance of embracing all emotions in the healing process, and surprisingly, the role that dance played in her journey. Plus, she gives us insights about developing resilience and the mindset shifts needed to thrive with chronic illness. Whether you're on your own health journey or just curious, this conversation is packed with inspiration and practical takeaways. Don't miss it!For the complete show notes and links visit inspiredliving.show/191
I'm thrilled to have Dr. Casey Kelley join me in this episode! Casey is a family medicine physician who transitioned to integrative health after her own tough battle with postural orthostatic tachycardia syndrome (POTS). We chat about her inspiring journey, the significance of digging into root causes of health issues, especially with autoimmune diseases, and discuss practical lifestyle steps anyone can adopt for better health. She explains POTS and its symptoms, shares insights on how stress and environmental factors can trigger autoimmune responses, and provides her framework for foundational health practices. If you've ever felt dismissed by conventional medicine or want to take charge of your wellness, this conversation is for you. Tune in to learn how to understand your body and foster healing in a supportive way!For the complete show notes and links visit inspiredliving.show/190
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below. Listen to the full episode. Dr. Grace Liu PharmD is an IFM-trained functional medicine practitioner and founder of The Gut Institute. She is a clinical pharmacist with a doctorate in practice for 20+ years and specializes in complex disease management. Dr. Liu consults and helps clients gain optimal performance through rebuilding the microbiome after damage from modern living. You can find her at thegutinstitute.com. In this episode: How gut health affects hormone balance and weight loss. Why the SARS-CoV-2 virus and certain vaccines could be influencing gut health. How gut bacteria can influence testosterone levels. Why addressing the root cause of inflammation can positively impact both men and women. Harmful effects of low fiber diets on gut health. The pivotal role of peptides in achieving health goals. Why addressing the mental component of weight loss is crucial. How emotional trauma can contribute to self-sabotage and weight gain. The concept of microdosing and how GLP-1 agonists can bolster gut health and weight loss. The connection between gut health and hormone health. How parasites and Candida can contribute to premature aging. The role of good flora in the gut. The importance of dietary fiber and prebiotics in supporting gut health. How synthetic peptides can potentially help in healing and reaching health goals. Effects tat emotional trauma can have on weight gain. The power of biohacking tools, such as peptides, to help people lose weight. Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Join me for a conversation with Lori Graham, a former occupational therapist turned functional medicine advocate. Lori shares her inspiring journey of shifting from conventional healthcare to recognizing the root causes of health issues. We discuss her book, "Dysfunctional Medicine," and how traditional medicine often overlooks the significant role of nutrition. Lori explains how functional medicine empowers individuals to take charge of their health through lifestyle choices and the importance of personalized care. From unique lab testing approaches to the concept of "inflammaging," Lori provides insights on how food can either drive health or illness. We also touch on the need for individualized health plans and strategies to maintain muscle mass as we age. If you're ready to challenge conventional health norms and prioritize wellness through informed choices, this episode is for you. Tune in and discover actionable steps to reclaim your health!For the complete show notes and links visit inspiredliving.show/189
In this eye-opening fertility episode, Dr. Wendy Trubow, MD, IFMCP, peels back the curtain on one of the most misunderstood issues in reproductive health: the toxic load we carry — and how it's silently sabotaging fertility in both men and women.Wendie Trubow, MD, MBA,IFM certified practitioner, is passionate about helping women optimize their health and lives as a functional medicine gynecologist. Through her struggles with mold and metal toxicity, Celiac disease, and other health issues, Trubow has developed a deep sense of compassion and expertise for what her patients are facing. She is the co-author of Dirty Girl: Ditch the Toxins, Look Great, and Feel Freaking Amazing and has been regularly featured in MindBodyGreen.This conversation isn't just for those trying to conceive — it's for anyone who wants to understand how the environment, food system, stress, and personal care industry are all intersecting with the skyrocketing rates of infertility, autoimmune diseases, metabolic disorders, and hormonal imbalance.Key InsightsWhy infertility is a symptom — not your identityHow inflammation blocks conception, even when all your tests look "normal"Why sperm counts are plummeting — and what that means for the futureHow to detox SAFELY before pregnancy — and what to avoid once you're pregnantWhy managing stress is just as important as managing toxins"You can't detox if you're stressed out — because stress turns OFF your detox pathways."The Three Toxic Buckets That Fuel InflammationWhat you put IN your bodyFood, plastics, pesticidesWhat you put ON your bodyMakeup, lotions, laundry detergentsWhat surrounds youAir, water, EMFs in your home + environmentDr. Wendy's JourneyDr. Wendy shares her personal story of toxic overload — despite doing "everything right" — and how she turned it into a roadmap for healing in her bestselling book "Dirty Girl."Recommended Clean Products & BrandsBeautyBeautyCounterBurt's BeesMineral FusionCleaning & LaundryAspen Clean (EWG Certified)Water FiltersBerkeyAquasanaReverse Osmosis systemsAir FiltersIQ Air ATEM (for cars)Air DoctorMolekuleResources
Join me in this episode where I chat with Mary-Beth Newell, a seasoned registered nurse with nearly 45 years of experience, about her insightful book, "Anti-Aging and Secrets of Healthy Living to Stop the Clock." Mary-Beth shares her journey and the holistic practices that keep her looking and feeling youthful. We dive into her five pillars of healthy living—exercise, nutrition, self-care, skincare, and enhancing natural beauty. Hear practical tips like doing squats while you brush your teeth and the importance of hydration. We also discuss the critical role of self-care for wellness and mental health, alongside unique practices like facial exercises and acupuncture. Whether you're looking to enhance your well-being or simply explore the secrets of aging gracefully, this episode offers actionable advice that fits into your life. Let's stop the clock together!For the complete show notes and links visit inspiredliving.show/188
Join me in this episode as I talk with Corey Levy, an expert in indoor air quality and mold remediation. We explore the surprising connection between the air we breathe and our health, particularly for those dealing with autoimmune conditions. Corey shares his personal journey into this field, shaped by his family's struggles with mold and illness. We break down common misconceptions about mold, mycotoxins, and why a thorough inspection is essential to identify hidden risks in your home. Plus, Corey offers practical tips to improve your indoor air quality today. If you've ever wondered how your living space might be impacting your health, this episode is a must-listen! We're diving deep to help you breathe easier and feel better. Tune in!For the complete show notes and links visit inspiredliving.show/187
After seven years of trying, we've finally done it—this episode of Inside the Rope features one of the most influential figures in institutional investment in Australia: David Neal, CEO of IFM Investors and founding CIO and former CEO of the Future Fund, Australia's $300+ billion sovereign wealth fund. David takes us behind the scenes of building the Future Fund from the ground up—how a clean slate, a world-class board, and a clear long-term mandate allowed for a new investment philosophy rooted in flexibility, illiquidity premiums, and global best practice. We talk about the importance of strong governance, the benefits of a total portfolio approach, and why the endowment model still resonates in long-term capital allocation. Now at the helm of IFM Investors—a global institutional asset manager originally founded by Australian industry super funds—David shares insights into investing on behalf of working people, the tailwinds driving infrastructure investment globally, and why private markets are an increasingly powerful lever for value creation. IFM was conceived by a collective of Australian industry super funds with a bold ambition: to give working people access to the kinds of global, complex investments traditionally reserved for the ultra-wealthy. Today, IFM manages over $250 billion across infrastructure, private equity, credit, equities, and real estate—always with a clear mission to deliver strong, long-term outcomes for its members. If you're seeking clarity on private markets, this is a conversation not to be missed.
Movement can feel intimidating –or even scary– when you're dealing with chronic pain and inflammation. I get it. That's why I invited strength trainer Jennifer Patrick to share her practical approach to building strength and incorporating movement into your daily life. We discuss why "motion is lotion," how to distinguish between good and bad pain, and simple ways to move more without aggravating your symptoms. If you've been avoiding exercise because of your autoimmune condition, this conversation will show you how small, manageable movements can make a big difference in your healing journey.For the complete show notes and links visit inspiredliving.show/186
I'm thrilled to welcome back James Schmactenberger to talk about a well-known, and inexpensive mineral that could be your missing link to recovery. Did you know over half of us are magnesium deficient? Even if you eat well and take supplements, you might not be getting what your body needs. James explains why most magnesium supplements fall short and how this affects your sleep, stress levels, digestion, and brain function. We dig into the difference between magnesium getting into your bloodstream versus actually being used by your tissues, and why multiple forms of this mineral matter. If you're dealing with unexplained symptoms, muscle pain, or brain fog despite your best efforts, this conversation could be the game-changer you've been looking for in your healing journey.For the complete show notes and links visit inspiredliving.show/185
In this episode I talk with energy healer Beth McIntyre about why those chronic health issues might not be improving, despite your best efforts. Beth explains how hundreds of trapped emotions from everyday stress could be blocking your body's natural healing abilities. She shares her journey from years of depression to vibrant health using three powerful healing systems: The Emotion Code, Body Code, and Belief Code. If you've tried everything for your health concerns but still struggle, this conversation might reveal the missing piece. Learn how these structured energy healing approaches can quickly identify and clear emotional blockages that you may not even know you have. Beth's work shows that releasing trapped emotions and limiting beliefs could be the key to unlocking your healing potential.For the complete show notes and links visit inspiredliving.show/184
In this episode of the Tick Boot Camp Podcast, Dr. Chris Turnpaugh of Turnpaugh Health shares his holistic approach to treating chronic Lyme disease and other tick-borne illnesses. He discusses the importance of addressing the whole body, not just killing the pathogen, and the role of neuroplasticity in recovery. Key topics include: Overview of Turnpaugh Health's multidisciplinary practice Dr. Turnpaugh's educational journey from chiropractic to functional medicine The inside-out approach of chiropractic and its impact on the nervous system Neuroplasticity and its influence on immune function and mood disorders Natural antimicrobials like Crypto Lepus and Cat's Claw Biofilm disruptors such as medical-grade stevia and NAC Supplements for sleep, mood, and mitochondrial support Dr. Turnpaugh provides valuable insights and practical recommendations for chronic Lyme patients seeking a comprehensive path to healing. Key Takeaways: Multidisciplinary approach addressing physical, emotional, and mental aspects of chronic illness Importance of supporting the body's physiology, not just killing pathogens Role of neuroplasticity in chronic Lyme and strategies for retraining the nervous system Natural antimicrobials and biofilm disruptors as part of a holistic treatment plan Supplements for sleep, mood, and mitochondrial health About Dr. Chris Turnpaugh: Dr. Chris Turnpaugh is the founder and President of Turnpaugh Health & Wellness Center, leading a team dedicated to patient-focused, integrative care. With post-doctorate certification in functional neurology and training from the Carrick Institute, the Institute for Functional Medicine, and A4M, he specializes in autoimmune diseases, thyroid disorders, neurological conditions, and anti-aging medicine. Beyond his clinical practice, Dr. Turnpaugh is an educator, teaching healthcare providers nationwide about functional medicine principles. He is an active member of the International Lyme Disease Association, PCA, A4M, IFM, and the International Association for Functional Neurology. When he's not treating patients or educating practitioners, Dr. Turnpaugh enjoys hiking, scuba diving, and cheering on his favorite college football team. Products & Resources Mentioned Available on Dr. Turnpaugh's Website: Liposomal Cryptolepis: Broad-spectrum natural antimicrobial effective against Lyme, Bartonella, and other tick-borne infections Cats Claw Elite: Natural antimicrobial with anti-parasitic properties As Soon As you are Bit (ASAB - ASAB 2): ASAB is a potent herbal formulation meticulously crafted to combat tick-borne infections and ASAB 2 coverage extends to address persister cells that may emerge due to antibiotic usage and is effective against parasites. Mellow (Serenity DHH-B Complex): Sleep aid containing Dihydrohonokiol-B from Magnolia Bark to calm the nervous system Extinguisher: Anti-inflammatory blend with Turmeric, Resveratrol, Perilla Seed Extract, and Quercetin MitoSpark: Supports mitochondrial health and function Bitter X: Herbal bitters to support detoxification and bile flow for things like microplastics NAC+: Glutathione precursor to support detoxification and antioxidant status Turmero XL: Highly bioavailable turmeric extract for reducing inflammation Rejuvenate: Supports mast cell function and dampens inflammatory responses immunoREBOOT: Helps retrain the immune system and reduce inappropriate reactions Follow & Subscribe: If you enjoyed this episode of our Tick Boot Camp Podcast, be sure to subscribe and leave a review! Connect with us on social media for more expert interviews and insights into functional medicine and chronic illness recovery.
I talk with Functional Diagnostic Nutrition Practitioner Maddison Sutton about a game-changing wellness strategy most of us overlook: the afternoon break. Maddison shares how her corporate burnout led to severe health issues, and why slowing down finally helped when pushing harder failed. If you're a high-achieving woman juggling career demands while battling autoimmunity or chronic stress, you'll love her practical approach to self-care that doesn't require hours of your time. We discuss why perfectionism sabotages healing, how to check in with what your body truly needs each day, and why small acts of self-love (even watching cat videos!) can transform your health journey. A conversation packed with simple strategies you can implement today, no matter how busy your schedule.For the complete show notes and links visit inspiredliving.show/183
Joel Evans, MD, and Emily Stein, PhD, join Integrative Practitioner Content Specialist Avery St. Onge to discuss the relationship between the oral microbiome and women's health in a live interview at the 2025 Integrative Healthcare Symposium. About the Experts Joel M. Evans, MD, a board-certified OB/GYN and international lecturer, is the Director of The Center for Functional Medicine in Ridgefield, CT. He is also the Chief of Medical Affairs for the Institute for Functional Medicine. He continues to serve as the external lead of IFM Advanced Practice Module in Hormone Health since its inception in 2011 and was a Co-Creator of the IFM course on COVID-19, lead its Post-Covid Initiative and has co-authored three published papers on the pandemic. Emily Stein, PhD is co-founder and CEO of Primal Health LLC, a Life Sciences company aiming to revolutionize oral and systemic health through the development of novel oral microbiome modulatory products, with a current focus on the root cause of biofilm-related oral diseases. She brings a deep understanding of the intricacies of the bacterial-human interface to preventative healthcare.
In this episode of Fashion InsideOut, Léo Migotti Ramponi, professor of Cognitive Sciences at IFM, examines the understanding of music and fashion as languages and their power of transmission. Léo analyzes music choices for fashion shows, showing why and how music is used to change clothing's perception. We also look at emerging forms of musical creation, including AI-generated compositions, which are pushing creative boundaries and redefining the role of music in fashion. ◾ “Fashion InsideOut” is a podcast series where students interview and exchange with professors and researchers at Institut Français de la Mode. Each episode concentrates on a different issue of the fashion and creative industries. Join “Fashion InsideOut”, the fashion conversation from inside our campus out to you. Host: Dolorès Buffet-Meziani (BSc in Management for Fashion & Creative Industries) Podcaster: Léo Migotti Ramponi Recording & Editing: Isabelle Field Music: Universal Music France ◾ FOLLOW US, JOIN IFM COMMUNITY! Suivez nous et rejoignez notre communauté ! Instagram @ifmparis www.instagram.com/ifmparis Facebook @ifmparis www.facebook.com/ifmparis TikTok @ifmparis www.tiktok.com/@ifmparis Twitter @ifmparis twitter.com/IfmParis LinkedIn www.linkedin.com/company/institut…cais-de-la-mode/
In this episode I am joined by Elaine Hicks, a licensed clinical social worker who's pioneering a unique approach to healing by combining freediving with nervous system therapy. If you're dealing with chronic pain or autoimmunity, you'll discover practical techniques you can use immediately – no water required! Elaine breaks down polyvagal theory into simple zones that help explain why your body reacts the way it does, and shares specific breath work, ice pack applications, and body awareness practices that can shift your nervous system state within minutes. Learn why traditional relaxation advice often fails and how finding your body's "safety zones" can be transformative for healing. Plus, find out why blowing bubbles might be your first step toward better health!For the complete show notes and links visit inspiredliving.show/182
In this episode I look at Functional Medicine, a movement which started in the USA and is practised predominantly by non-medical practitioners but also increasingly medical doctors. It comes under a lot of fire from doctors and I want to explore why this, including that is isn't ‘medicine' and what the differences and similarities are between functional medicine and conventional allopathic medicine.Links:Intro to functional medicine by IFM: https://www.ifm.org/functional-medicineA review of functional medicine by Jeffrey Bland: https://pmc.ncbi.nlm.nih.gov/articles/PMC9173848/Methylation explained: https://www.healthline.com/health/methylation#takeawayMethylation, a view from a functional medicine practitioner: https://www.drkarafitzgerald.com/2016/08/01/methylation-whats-fuss/The British College of Functional Medicine: https://www.bc-fm.org/Patient story from The Cleveland Clinic: https://my.clevelandclinic.org/patient-stories/196-functional-medicine-helps-woman-regain-her-life-after-44-years-of-chronic-painAn allopathic doctors view: https://www.doctormather.com/blog/redflagsLimitations of Evidence Based Medicine: https://www.sciencedirect.com/science/article/pii/S0735109716331370 Evidence Based Medicine: https://bmjopen.bmj.com/content/12/11/e067268 Hosted on Acast. See acast.com/privacy for more information.
Jeffrey Bland, PhD, FACN, FACB, CNS, joins Integrative Practitioner Content Specialist Avery St. Onge to discuss how he became the father of functional medicine and what he envisions for the future of integrative healthcare. About the Expert Dr. Jeffrey Bland is a personable and highly respected thought leader who has spent more than five decades focused on the improvement of human health. He is known worldwide as the founder of the Functional Medicine movement, which represents his vision for a care model that is grounded in systems biology and informed by research that he has a unique ability to synthesize. His pioneering work has created the Personalized Lifestyle Medicine Institute, as well as the Institute for Functional Medicine, the global leader in Functional Medicine education. Since 1991, hundreds of thousands of healthcare practitioners have participated in PLMI and IFM programs, and this collective knowledge has positively impacted the lives of patients all over the world.
My conversation with Andrea Nakayama gets to the heart of why many of us struggle with autoimmune recovery despite doing "all the right things."Andrea shares how she developed a different approach to functional medicine after her own life-changing experience, and explains why deep listening might be the missing piece in your healing journey. Whether you're feeling stuck with protocols that aren't working or just starting your recovery journey, you'll learn practical ways to tap into your body's wisdom and become the expert of your own health. Andrea also reveals the surprising science behind belonging and healing - it's not what you might think!For the complete show notes and links visit inspiredliving.show/181
Kristi Morlan-Hughes, ND, IFMCP, FMCHC has dedicated her professional path to the study and practice of root-cause medicine. After graduating from the National College of Natural Medicine, she launched her original private practice in 1997 in Alexandria, MN. She attended her first training with the Institute for Functional Medicine in 1999, becoming certified in 2015, which further reinforced her nutrition and natural medicine skills. Dr Kristi's practice embraces a root-cause care approach to managing mystery illnesses, medical challenges, and provides patient advocacy for those dealing with chronic diseases striving to get the most out of their health care team and the medical system. Dr. Morlan-Hughes served as a Director of Medical Education at IFM for a decade, where she was responsible for the development of medical education, nutrition-oriented resources, and clinical tools to support patient education. She supported the Collaboration partners working with IFM, cultivated practice implementation assets, and participated as an educator and facilitator both domestically and international. Dr. Kristi remains connected to core training programs at IFM, she continues to mentor students and practitioners alike in her mentorship program. You can find Dr Kristi on LinkedIn Or her homepage Website · Instagram · FaceBook · X · BioSite · LinkedIn · YouTube
Kristi Morlan-Hughes, ND, IFMCP, FMCHC has dedicated her professional path to the study and practice of root-cause medicine. After graduating from the National College of Natural Medicine, she launched her original private practice in 1997 in Alexandria, MN. She attended her first training with the Institute for Functional Medicine in 1999, becoming certified in 2015, which further reinforced her nutrition and natural medicine skills. Dr Kristi's practice embraces a root-cause care approach to managing mystery illnesses, medical challenges, and provides patient advocacy for those dealing with chronic diseases striving to get the most out of their health care team and the medical system. Dr. Morlan-Hughes served as a Director of Medical Education at IFM for a decade, where she was responsible for the development of medical education, nutrition-oriented resources, and clinical tools to support patient education. She supported the Collaboration partners working with IFM, cultivated practice implementation assets, and participated as an educator and facilitator both domestically and international. Dr. Kristi remains connected to core training programs at IFM, she continues to mentor students and practitioners alike in her mentorship program.You can find Dr Kristi on LinkedIn Or her homepage
If you're like me, coffee is non-negotiable - but what if your daily coffee ritual is secretly working against your health?I'm joined by Dr. Vincent Pedre, who shares some eye-opening truths about how our coffee habits might be triggering gut inflammation. We dive into the hidden toxins in most coffee products, why your brewing method matters more than you think, and how to make your daily cup actually support your gut health.Dr. Pedre breaks down the science of coffee's impact on our bodies and shares practical tips to transform your morning routine. Whether you're dealing with acid reflux or just want to make healthier choices, you'll want to hear this before your next cup of coffee.For the complete show notes and links visit inspiredliving.show/180
I talk with genomics expert Jaclyn Downs about what you really need to know about genetic testing when dealing with autoimmune conditions. If you've ever wondered why your MTHFR gene test didn't give you the answers you needed, or why following general supplement recommendations isn't working, this episode is for you. Jaclyn breaks down the common misconceptions about genetic testing and explains why your genes are more like dimmer switches than on/off buttons. You'll learn why most genetic reports miss the mark and what information you actually need to make your genetic data useful for your healing journey.For the complete show notes and links visit inspiredliving.show/179
In this episode, I sit down with Dr. Melanie Keller, ND, a renowned expert in the treatment of IBS (Irritable Bowel Syndrome) and SIBO (Small Intestinal Bacterial Overgrowth), to explore the autoimmune components of these conditions and discuss new, groundbreaking treatment methods. For the complete show notes and links visit inspiredliving.show/178
In this episode, we dive deep into the complex world of sleep with our guest, Annika Carroll, an expert sleep specialist and CEO of Sleep Like a Boss.We explore the myriad of factors that can contribute to sleep problems – such as lifestyle behaviors, mindset, inflammation, and physiological issues – and practical steps to improve your sleep. In an eye-opening discussion, we shed light on the interconnectedness of the human body, from gut health to cortisol regulation. For the complete show notes and links visit inspiredliving.show/177
In this episode I was joined by Dr. Saima Khan, who shares her incredible journey of using functional and integrative medicine to conquer narcolepsy after traditional Western medicine failed her.Dr. Saima has transformed her life from dependency on stimulants and drugs to living a life filled with purpose, and now, she helps others with chronic illness to challenge the belief that their diagnosis and medications are the only solutions for their symptoms. For the complete show notes and links visit inspiredliving.show/176
In this episode, I speak with Dr. Bradley Shepherd about the intricate connections between nutrition, hormones, and chronic pain. We explore how dietary choices and nutrient deficiencies impact hormone balance and overall health. Dr. Shepherd shares his top foods for hormone health and explains the importance of dietary variety. We also discuss the role of gut health in nutrient absorption and how addressing hormone imbalances can be crucial in managing chronic pain conditions.For the complete show notes and links visit inspiredliving.show/175
In this episode I was joined by Jamie Hartman, a pioneer in the field of autoimmune wellness. She shared her personal journey with Crohn's disease and how she transformed her health through the autoimmune protocol (AIP).We delved into the evolution of the AIP diet, including the traditional approach and the new, less restrictive modified plan. We also touched on the importance of lifestyle factors in managing autoimmune conditions and debunked some common myths surrounding AIP. For the complete show notes and links visit inspiredliving.show/174
Have you been wanting to start a meditation practice but feel overwhelmed or unsure where to begin?Jeff Patterson, founder of The Yielding Warrior and meditation expert with over 30 years of experience, reveals the three essential elements that can help anyone build a successful meditation practice. From movement-based options like Tai Chi to simple breathing techniques you can do anywhere, Jeff breaks down meditation into practical, actionable steps that work for real life. Whether you're dealing with chronic health issues, seeking better stress management, or simply want to improve your overall wellbeing, this episode provides a clear roadmap to start your meditation journey today. Discover why the common beliefs about meditation might be holding you back and learn how to build a sustainable practice that fits your lifestyle.For the complete show notes and links visit inspiredliving.show/173
Discover why sleep might be the missing piece in your healing journey; naturopathic doctor Holly Donahue reveals the profound connection between sleep quality and your body's ability to heal naturally.From hormone balance to immune function, learn why sleep deprivation could be sabotaging your health goals and natural healing efforts. Holly shares her expertise on how sleep impacts everything from blood sugar regulation to stress management, and why traditional treatments often fail without addressing sleep quality first. Whether you're dealing with chronic health issues or simply want to optimize your wellbeing, this episode uncovers why quality sleep isn't just about rest—it's about giving your body the foundation it needs for true healing. Learn why prioritizing sleep could be the game-changer in your path to wellness.For the complete show notes and links visit inspiredliving.show/172
This episode covers:In this episode, we discuss the difference between allergies and food sensitivities, the connection between the gut and skin, how a compromised gut can lead to the absorption of toxins and so much more.Dr. Maria Azizian is a board-certified general surgeon and IFM-certified functional medicine physician who has embraced functional medicine as the way forward in health care. After years of treating urgent medical conditions like perforated bowels and diseased gallbladders, she realized medicine should be about more than just reacting and removing. It should predict, prevent, and personalize. Dr. Azizian has a special interest in early prevention of chronic diseases and longevity/anti-aging supported by the latest studies. Her skin clinic, Mindful Medical Care in Falmouth, Massachusetts, focuses on skin conditions and skin cancer.Links mentioned during this episode:The Clear Skin Diet Book: https://amzn.to/4gcnVXmDr. Azizian's YouTube: https://www.youtube.com/@mariaazizianmdFunctional Medicine Clinic: www.mindfulmedicalfunctionalclinic.comLyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's Newsletter: www.thelyonsshare.org/newsletter