Podcasts about SPS

What should supply chain leaders be focused on as the second half of the year begins? This week's episode of The Buzz, powered by Zebra Technologies, delivers practical leadership advice, industry news, and expert insights to help organizations prepare for what's next. Supply Chain Now hosts Scott Luton and Kim Reuter explore the supply chain stories making headlines, from July 4th supply chain facts and rising food costs to the growing impact of GLP-1 medications on cold chain logistics and healthcare distribution. They also discuss why now is the time for supply chain leaders to conduct a mid-year operational review and begin planning for peak season. Later in the episode, Scott sits down with Todd Heimes, Vice President and General Manager of Amazon Business Worldwide, for an insightful conversation about AI, procurement transformation, automation, and Amazon Quick. Together, they discuss how organizations can reduce manual work, improve visibility, and use AI to build more agile procurement operations. The episode wraps with predictions for the remainder of 2026, including rising transportation costs, ongoing geopolitical disruptions, cargo theft, and what leaders should do today to stay ahead. Key Takeaways Conduct a mid-year operational review to compare projections against actual performance. Begin holiday and peak season planning now by partnering with marketing and merchandising teams. AI is helping procurement teams shift from reactive operations to proactive decision-making. GLP-1 medications are driving increased demand for sophisticated cold chain logistics. Visibility, automation, and reducing manual processes remain critical priorities for supply chain leaders. Organizations that embrace AI today will be better positioned to compete in the years ahead. Whether you're leading procurement, transportation, operations, or supply chain strategy, this episode offers timely insights you can immediately apply. From practical leadership advice and emerging logistics trends to AI-powered procurement innovations, The Buzz delivers actionable conversations that help supply chain professionals stay informed and stay ahead. Additional Links & Resources: Connect with Todd: https://www.linkedin.com/in/todd-heimes-854666/ Learn more about Amazon Business: https://business.amazon.com/ Prime Business Quick overview: https://business.amazon.com/en/blog/amazon-quick-prime-business-discount Reshape 2026: https://business.amazon.com/en/events/reshape Learn more about Zebra: https://www.zebra.com/machinevision Check out Zebra's guide to Warehousing and Logistics Solutions: https://www.zebra.com/content/dam/zebra_dam/en/guide/portfolio/warehousing-and-logistics-solutions-guide-portfolio-en-us.pdf/?tactic_type=SPS&tactic_detail=TL_TheBuzzPodcast_Video_ENUS_NA UPS to invest $48 million in temperature-controlled facilities amid healthcare boom: https://cnb.cx/4eDjwO1 The Sustainability Voice Missing From Most Boardrooms: https://bit.ly/Voice-Missing-on-Sustainability U.S. watermelon production reached 3.7 billion pounds in 2024, with Florida leading output: https://www-tx.ers.usda.gov/data-products/charts-of-note/112972 Upcoming Live Programming:  https://supplychainnow.com/upcoming-live-programming/ Supply Chain Now Resource Hub: https://supplychainnow.com/resource-hub/ Learn more about our hosts: https://supplychainnow.com/about Learn more about Supply Chain Now: https://supplychainnow.com Watch and listen to more Supply Chain Now episodes here: https://supplychainnow.com/program/supply-chain-now   Subscribe to Supply Chain Now on your favorite platform: https://supplychainnow.com/join   Work with us! Download Supply Chain Now's NEW Media Kit: https://bit.ly/3XH6OVk WEBINAR- The Future of Supply Chains: Where Talent Meets Technology: https://bit.ly/4uUuxkc WEBINAR- Peak Reality Check: What Shippers, Analysts, and AI Models Are Predicting for 2026: https://bit.ly/4aTlsRv WEBINAR- From Volume to Resilience: How Automotive Supply Chains Are Adapting to a New Market Reality: https://bit.ly/4f6SUGA WEBINAR- The Automotive Industry's Next Digital Breakthrough: https://bit.ly/4vhUwT4 This episode was hosted by Scott Luton and Kim Reuter, and produced by Trisha Cordes, Joshua Miranda, and Amanda Luton. For additional information, please visit our dedicated episode page at: https://supplychainnow.com/buzz-amazon-business-glp-1-logistics-mid-year-supply-chain-leadership-pulse-check-1607   The content in this episode, including all audio, videos, visuals, and graphics, is the property of Supply Chain Now and is protected by copyright law. Unauthorized use, reproduction, distribution, modification, or re-uploading of this content in any form is strictly prohibited without explicit written permission from Supply Chain Now.For licensing inquiries or permissions, please contact us at production@supplychainnow.com© 2026 Supply Chain Now. All rights reserved. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

As a holistic and functional psychiatrist, I see many people who are highly sensitive. Most are deep divers into information and able to connect a lot of dots. Many are gifted. Many struggle with overwhelm and low stress tolerance. Some struggled with anxiety, inner tension, or feeling “too much” for as long as they can remember. Some feel different - that they don't fit in.As a holistic and functional psychiatrist with over twenty years in practice, I've worked with thousands of highly sensitive adults and children. Most are deep divers into information, able to connect a lot of dots — many are gifted. And yet many struggle with overwhelm, low stress tolerance, anxiety, or inner tension that has been there for as long as they can remember. Many feel different, like they don't quite fit in. What I've found is that sensitivity itself is rarely the problem — it's the seeming vulnerability to brain-related or physical conditions. Over the years I've found three different models to be especially useful in explaining some of the vulnerabilities and the strengths of those of us who are highly sensitive: Dr. Elaine Aron's work on the Highly Sensitive Person (HSP), the nutritional medicine concept of Pyrrole Disorder, and Dr. Sharon Meglathery's RCCX Theory. Each looks at a similar group of traits through a different lens — psychological, biochemical, and genetic, respectively.Before I start, I want to emphasize that sensitivity is not a pathology or a diagnosis. It is actually a trait that has existed across human history for a reason. My goal is not to pathologize it, but to understand it — and to offer tools to those who have these traits but who are struggling with a condition more prevalent in those with these traits. As I go through these three frameworks, the overlap will be obvious and I'll highlight what each of these has to offer that the others don't.What You'll Learn* The HSP model provides validation and a language for sensitive individuals.* Pyrrole Disorder involves an overproduction of pyrroles, leading to nutrient depletion of nutrients critical for neurotransmitter functioning.* Pyrrole Disorder is common in brain-related conditions.* RCCX Theory connects genetic vulnerabilities to sensitivity and chronic illness.* Stress amplifies the experiences of highly sensitive individuals.* Understanding these models can lead to effective treatment options.* There are meaningful paths forward for those who are highly sensitive.Chapters* 00:00 Understanding High Sensitivity* 02:26 The Highly Sensitive Person (HSP) Model* 10:23 Exploring Pyrrole Disorder* 18:18 RCCX Theory Explained* 30:11 Intersecting Models: HSP, Pyrrole Disorder & RCCX Theory* 34:40 Conclusion and Path ForwardI. THE HIGHLY SENSITIVE PERSONIn the early 1990s, psychologist Dr. Elaine Aron identified a personality trait she called Sensory Processing Sensitivity (SPS) — and the people who score high in it she called Highly Sensitive Persons, or HSPs.This is not a diagnosis. It is a trait, present in roughly 15–20% of the population. It has been found across more than 100 species — from fruit flies to primates. This tells us it is evolutionarily conserved — it confers survival advantages. In any social group, having members who are wired to notice subtle cues, process information deeply, and detect threats before others do is extremely valuable. Fitting with this, many of these individuals, who also struggle with complex chronic health issues are considered the “canaries in the coal mine” since their bodies react to environmental triggers (environmental toxins, chemicals, or stressors) long before the rest of the population.Dr. Aron captured the core features of this trait in an acronym she called DOES:D — Depth of processing: HSPs think deeply, reflect before acting, and notice subtleties that others miss.O — Overstimulation: Because they process so thoroughly, HSPs reach their threshold more quickly in high-stimulation environments.E — Emotional reactivity and Empathy: HSPs feel emotions intensely and are highly attuned to the emotions of those around them.S — Sensitivity to subtle stimuli: They pick up on things — in their environment, in social dynamics, in the body — that others simply don't register.As you can see, traits that are super powers, can become liabilities. The deep diver who loses sight of the big picture. The empath who absorbs everyone else's energy as their own energy becomes depleted. The person who withdraws from the world because the stimulation has simply become too much.HSP ResearchBeyond the clinical observations, there is now a growing body of neuroscience and genetic research supporting this trait. There is evidence that the brains of sensitive people are doing more, processing more and feeling more.fMRI studies (Acevedo, Aron et al., 2014) have shown that when HSPs view emotional images — particularly photos of loved ones expressing happiness or sadness — their brains show significantly greater activation in regions associated with awareness, empathy, and sensory integration.Twin studies show that Sensory Processing Sensitivity (SPS) as defined by Dr. Aron is approximately 47% heritable. Small studies as opposed to large genome wide studies have focused on genetic variants involving dopamine and serotonin systems, such as a serotonin transport gene, a dopamine receptor gene, and COMT, which codes for the enzyme that metabolizes dopamine and norepinephrine.While this hints at a biochemical dimension, the HSP framework doesn't address this as directly as the other two models I'll discuss, nor does it explain the higher prevalence of physical health conditions in those who are highly sensitive.Research published in 2026 (Matsuzawa et al.) found that individuals high in SPS had substantially higher rates of depression (13.8%), anxiety disorder (10.5%), and developmental disorders, such as ADHD and ASD, compared to the general population.Despite this overlap with developmental disorders: unlike, ADHD, HSPs typically have excellent concentration in quiet environments. And unlike the social deficits described in ASD, HSPs tend to have heightened social attunement. They often feel too much of what's happening in social situations, not too little, even if they respond awkwardly at times.Research shows that high sensory processing sensitivity is associated with more frequent physical symptoms — back pain, fatigue, digestive issues, frequent illness.What This Framework OffersThe HSP model has given millions of people validation and a language for these traits that has allowed them to shift from “what is wrong with me” to “this is how I am wired.”It also offers an evolutionary reframe. High sensitivity is not a mistake and is not pathologic. It is a feature of the human population that has served us.What it doesn't offer is a biological explanation for why some sensitive people suffer so acutely — or a path toward biochemical intervention. II. PYRROLE DISORDERPyrrole disorder is a biochemical imbalance that has been recognized for decades, though it remains largely unknown in mainstream psychiatry. It involves an overproduction of pyrroles — metabolic byproducts that, on their own, are not a problem. When they are high, however, they can result in a depletion of zinc, B6 and a few other nutrients.First identified in the 1950s and first treated with zinc and B6 in the 1980s, pyrrole disorder is one of the most common nutrient imbalances found in brain-related conditions — and one of the most treatable. Yet most people who have it have never heard of it. I learned about pyrroles in 2014 when I first trained with the Walsh Research Institute.The Importance of Zinc, B6 & MagnesiumVitamin B6 is required to synthesize dopamine, serotonin, and GABA — three of the most critical neurotransmitters for mood regulation, anxiety, and stress response. Zinc plays a profound role in the central nervous system, the immune system, gastrointestinal tract (which we now know has its own significant influence on brain health) and connective tissue (joints and skin).Pyrrole Disorder Traits & SymptomsThe most consistent feature is low stress tolerance. People with elevated pyrroles are often described as those for whom life seems harder than it should be, every transition can be destabilizing and every large group or new environment feels like too much.The overlap with the HSP profile is striking, but here, we start to see not only traits, but symptoms.- Socially anxious, shy, or fearful since childhood, with severe inner tension- Sensitive to bright light, loud noises, textures, and odors- Avoids crowds, strangers, and new situations- History of reading difficulty- Poor short-term memory- Underachievement- Irritability, mood swings, bouts of depression- Tends to stay up late; little or no dream recall; morning nausea- White spots on fingernails; very dry skin; stretch marks; poor wound healing- Joint pain- Frequent infections or autoimmune tendenciesMost people with pyrrole disorder don't have all of these symptoms — but the inner tension, the high sensitivity, and low stress intolerance are very common.What the Data ShowsThe Walsh Research Institute has collected data on over 30,000 patients. Elevated pyrroles were found in:* 18% of those with ADHD* 24% of those with depression* 28% of those with behavioral disorders* 35% of those with autism* 35% of those with bipolar disorder* 30% of those with schizophrenia* 12% of those with PTSDAnd in only 8% of healthy controls — meaning those with no psychiatric diagnosis.What Causes Pyrrole Disorder?For many, there appears to be a genetic component, but for others, pyrroles appear to have increased due to high physiologic or emotional stress. Examples include candida overgrowth or other forms of gut microbial imbalances, mold toxicity, heavy metals, chemical exposures, illness, emotional trauma, major life transitions or even growth spurts in children.What This Framework Brings UsRelative to the HSP framework, an understanding of pyrroles gives a specific, treatable biological mechanism. When zinc, B6, Magnesium and other nutrients are depleted, we know how the brain's neurotransmitter functioning is affected — and we know what to do about it.Treatment from a Walsh Research Institute trained practitioner typically involves a nutrient protocol of zinc (based on zinc and copper testing), B6 or its active form P5P, and other nutrients for pyrrole disorder and other nutrient imbalances identified. For many patients, a lifetime of chronic inner tension and fearfulness begins to shift within days to a couple of weeks of starting the nutrients.Treatment doesn't change one's personality, but it can improve social discomfort, overwhelm, the anxiety, the depression that has been layered on top of that sensitivity.Where zinc deficiency can impact a lot of the physical conditions that appear to be more common in those who are hypersensitive, it doesn't fully explain the significant hormonal, inflammatory, connective tissue symptoms and autoimmunity we see in many who are hypersensitive.III. RCCX THEORYRCCX theory has been proposed by Dr. Sharon Meglathery, MD — a psychiatrist and internist whose own complex health history (which is very similar to my own) led her to one of the most compelling explanations I've encountered for why hypersensitivity, neurodivergence, psychiatric conditions, MCAS (Mast Cell Activation Syndrome), EDS (Ehlers Danlos Syndrome), POTS (Postural Orthostatic Tachycardia Syndrome), CIRS (Chronic Inflammatory Response Syndrome) and/or CFS (Chronic Fatigue Syndrome) and autoimmunity tend to cluster together in certain individuals and families.RCCX refers to a module of four genes on chromosome 6. Three of them appear to be particularly important to our health, and two of those have very high rates of mutation.The Three Key Genes(1) TNXB codes for a protein involved in connective tissue. Variants range from subtle joint hypermobility to Ehlers-Danlos Syndrome. But connective tissue isn't just about joints — it's also about the permeability of the gut-blood barrier, the blood-brain barrier, and vulnerability to upper cervical (neck) instability, which can put tension on the vagus nerve and affect the entire autonomic nervous system.(2) CYP21A2 is the most important gene in the module when it comes to psychiatric conditions. It codes for 21-hydroxylase, an enzyme needed to convert 17-hydroxyprogesterone into cortisol. When there is a mutation — and there can be many, of varying degrees — the body may struggle to meet the demand for cortisol under stress. A weakness on this gene could have two primary effects:First — The theory holds that many people with CYP21A2 mutations, even without hypermobility, may develop what Dr. Meglathery calls a “brain wired for danger” — essentially, a nervous system calibrated toward threat detection from early in life, with minimal trauma required. A mutation on CYP21A2 may essentially result in relatively higher androgens impacting the amygdala — the brain's fear and emotional center. Studies have found that hypermobile individuals (who often carry TNXB mutations) have a larger-than-normal amygdala.Second — because of this mutation, the body may not be able to keep up with the body's need for cortisol (especially when under stress). This deficit causes the brain to release corticotropin releasing hormone (CRH) to signal the adrenal glands to produce more cortisol. CRH binds to mast cells and activates the immune system — leading to secondary brain inflammation. This is the inflammatory pathway that can result in a number of secondary health issues including MCAS, CIRS, POTS, CFS and more.(3) C4 is involved in immune response and autoimmunity, and has been linked to schizophrenia. This gene variant is not as common as the first two referenced, though I do see a number of families who also have autoimmunity impacting multiple family members.The CAPS Psychological ProfileDr. Meglathery uses the term CAPS — CYP21A2 Mutation Associated Neuropsychiatric Spectrum — to describe the psychological profile she has observed in people with this genetic vulnerability. These traits can exist long before any formal psychiatric diagnosis, and they are not inherently pathological. - Anxiety and over-arousal during times of stress — high adrenaline, insomnia, sometimes manic-like characteristics- Under-arousal during low-stress periods — leading to ADD presentations, compulsive behaviors, or thrill-seeking to raise arousal- High emotionality, sensitivity, and reactivity to environmental stimuli- Sensory processing difficulties — typically over-stimulation in loud or chaotic environments- A strong ability to read emotions in others, paired with social awkwardness in response- Easily affected by events others would consider minor — an offhand comment, a disturbing movie- A tendency toward nonconformity- Special abilities: gifted musicians, scientists, creatives, systems thinkers- Hyper-focus and obsession with areas of deep interest, often leading to remarkable accomplishments- High tenacity and determination, when not derailed by overstimulation or past trauma- Strong emotions — positive or negative — that can manifest as obsessional worrying, harm avoidance, OCD tendencies, or very high standards for self and othersDr. Meglathery also notes — and I have observed this clinically — that people with this profile tend to find each other through friendships, partnerships and marriage. They are drawn together by shared sensitivities, emotional depth, and intellectual gifts. This means children are likely to receive a tendency towards CAPS from both sides.Women who are appear to have CYP21A2 mutations often have a male-pattern finger length ratio — the ring finger longer than the index finger — a possible marker of androgen exposure during development.What RCCX OffersRCCX theory offers the broadest biological framework we have for understanding why sensitivity, psychiatric vulnerability, and complex chronic illness so often travel together in the same people and families. It connects the nervous system, the immune system, the hormonal system, and connective tissue under one genetic umbrella.It also points toward specific interventions: nervous system regulation (limbic retraining, vagal work), mast cell management, and addressing the downstream biochemical consequences of cortisol dysregulation.The limitation is that genetic testing for variants on the gene for 21-hydroxylase is not yet widely available, which is why this isn't a gene that you'll see referenced when it comes to HSP, though I would argue it is likely the most prevalent. RCCX remains a clinical theory — but one that explains the constellation of traits and symptoms of most of the people that I in my practiceIV. WHERE THESE MODELS INTERSECTWhere Might Pyrrole Disorder and RCCX Theory Meet?The symptom overlap is almost complete: poor stress tolerance, sensory sensitivities, anxiety, inner tension, connective tissue symptoms, frequent infections, autoimmune tendencies. Relatively low zinc would impact most of these shared symptoms, but there may be a potentially deeper connection.21-hydroxylase contains a pyrrole-like structure — heme — within it. Could a mutation resulting in abnormal 21-hydroxylase lead to a buildup of abnormal heme-like compounds, contributing directly to pyrrole disorder? This is not proven, but in an exchange about this with Dr. Meglathery, she indicated that she also believes there is a strong association, and the biochemical logic is compelling.This matters, because we know what helps pyrrole disorder. We have a treatment — treatment that can complement what RCCX theory makes evident — that the stress response has to be addressed.Stress (again from any cause - physiologic or emotional) is the great amplifier across all three models. Stress worsens the HSP experience, and tips the CYP21A2 mutation from manageable to destabilizing (through the hormonal consequences and the inflammatory cascade) and yes, it even causes pyrroles to increase.BRINGING IT TOGETHERFor someone who is highly sensitive, and struggling with brain related or physical symptoms or conditions, pyrrole disorder and even RCCX theory are worth considering because they offer tools and start to answer, “What Can We Do About It?”The three frameworks work together:The HSP model offers validation and language. It shifts the frame from deficit to difference. It reminds us that sensitivity is not pathology — it is a trait with evolutionary value, and it comes with great strengths.The Pyrrole model offers a treatable nutrient imbalance. It explains, at the neurotransmitter level, why stress hits harder for these individuals. Treatment doesn't take away the sensitivity; it lifts the weight that has accumulated on top of it.The RCCX model offers the broadest systems view. It connects the dots between what the body is doing — the immune activation, the hormonal dysregulation, the connective tissue involvement — and the psychiatric and psychological profile that tends to accompany it. It also provides additional tools: nervous system regulation, mast cell support, hormonal awareness.If any of this resonates — the sensitivity, the inner tension, the feeling of always being at the edge of overwhelm — please know that there are roots to explore and meaningful paths forward.If you are looking for someone trained by the Walsh Research Institute knowledgeable in assessing for and treating pyrrole disorder (and other common nutrient imbalances impacting brain health), or learning more about Dr. Aron's work on HSP and Dr. Meglathery's RCCX theory, I am providing those links below.And as always, I welcome your thoughts, experience and questions.Until next time,CourtneyAbout the AuthorDr. Courtney Snyder MD is a Holistic and Functional Child and Adult Psychiatrist who offers non-patient consultations to individuals and practitioners nationally and internationally in addition to her treatment practice serving FL, IN, KY, OH. Her educational content, shared through her website, Substack Newsletter, the Holistic Psychiatry Podcast and YouTube Channel reaches readers and listeners in over 160 countries.ResourcesWalsh Research Institute: walshinstitute.orgRCCX Theory — Dr. Sharon Meglathery: rccxandillness.comDr. Elaine Aron — The Highly Sensitive Person: hsperson.comOther Sources: Acevedo et al. 2014, “The Highly Sensitive Brain,” Brain & Behavior | Matsuzawa et al. 2026, Psychiatry & Clinical Neurosciences ReportsMedical Disclaimer:This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe

The ASX 200 rose 59 points today to close at 8823 (0.7%), with the banks solid. CBA rose 1.0% and NAB gained 1.0%, with the Big Bank Basket up to $271.94 (0.8%). Other financials also had a good session, with NWL rising 3.1% and ZIP enjoying a strong day, up 8.7%, along with XYZ, up 4.9%. Industrials were also firm, with the retail sector performing well. JBH rose 2.2% and ALL also pushed higher. Plenty of Ex Dividends today in REITs and utilities.Technology finally appears to be finding its feet, with WTC up 7.2%, XRO gaining 4.5%, and the old-school platforms REA, CAR, and SEK all rising around 4% or more. Utilities were weaker, with ORG down 1.0%, while APA traded ex-dividend and also drifted lower. Healthcare stocks were better across the board, with CSL up 0.5%, RMD gaining 2.0% and TLX rising 5.5%.Resources painted a mixed picture, with BHP up 1.4%, RIO up 0.3%, and FMG the best of the iron ore majors, up 2.4%. Gold miners were mixed as bullion drifted lower, with NST down 2.3% while GMD gained 1.9%. Lithium stocks were once again under early pressure but recovered to see PLS finish up 0.8%. In the oil and gas sector, WDS edged slightly higher, while some of the uranium stocks also posted modest gains.In corporate news, NEU had a stunning day following progress on European approval for Daybue. RMS rallied 2.3% after agreeing to sell its Edna May gold mine for $300m, while KAR rose 9.1% after restoring production at the SPS-92 well and announcing a new on-market share buyback.There was nothing of note on the economic front today.Nikkei 225 down 0.4%, South Korea up 1.1%, HK up 2% and Shanghai up 0.4%.US futures firm DJ up 191, Nasdaq up 215. European futures slightly higher.Marcus Today – Daily Market Insights Marcus Today provides clear, practical commentary for self-directed investors – covering markets, portfolios, education, and decision-making without the noise. If you'd like to go further: Start a free 14-day trial of Marcus Today http://bit.ly/mt-trial-podcast Join Marcus Today Use code MTPODCAST for 10% off http://bit.ly/mt-join-podcast-offer MT20 – Managed ETF Portfolio A professionally managed portfolio run by Marcus Padley and the team, using ASX-listed ETFs with active market timing. http://bit.ly/mt20-podcast Principles – How We Think About Investing A short video series on timing, behaviour, and decision-making. No stock tips. http://bit.ly/mt-principles-podcast — Disclaimer This podcast is general information only and does not consider your personal circumstances. It is not personal financial advice. 

This week the tables are turned on Matt Appleby as he guests on The Plant Based Podcast where he fields probing questions from HortWeek columnist and horticulture influencer Michael Perry (aka Mr Plant Geek) and horticulturist, floral designer, broadcaster and author Ellen Mary.Topics up for discussionHas RHS Chelsea Flower Show become too much about spectacle and not enough about gardening?Peat-free transition: Has the horticulture industry been set up to fall by unrealistic timelines, or has it been too slow to innovate?Is peat-free growing being successfully communicated to consumers?How is the horticulture trade on the continent reacting to the moves towards peat-free?Every year hundreds of exciting new plants are introduced and win awards, but why do so few hit the market?Are there any plants on the market that shouldn't be?How can we attract and support young people into the horticulture industry?Can the horticulture industry continue to rely on passion over pay?Are moves towards sustainble and ecological gardening making gardening too difficult, complicated and expensive?Should domestic horticultural production be supported more and will the SPS agreement help?AND FINALLY...What practice might horticulture look back on in 10 years' time and wonder how it was ever normal? Hosted on Acast. See acast.com/privacy for more information.

Ersetzt KI bald auch den Elektroniker oder trifft sie ausschließlich Büro- und Bildschirmjobs? In dieser Folge des Elektrotechnik Podcast zerlege ich genau diese Frage, technisch und ohne Weichspüler. Du erfährst, was ein Elektroniker in der Praxis wirklich macht, warum Messen, Prüfen, Inbetriebnahme und Fehlersuche etwas anderes sind als Sprach- und Klickarbeit und wo KI in der Elektrotechnik hilft, statt den Beruf einfach wegzurationalisieren.Quellen:Q1: Elektrotechnik Podcast # 211: Mit 50 in die Automatisierung? Dein Neustart mit Herzstrom & SPS https://open.spotify.com/episode/3BKNvL8971IYtUGkIBjPNA?si=DopxfDkDQkWWzRA1zjIvwQQ2: International Labour Organization – Generative AI and Jobs: A Refined Global Index of Occupational Exposure.https://www.ilo.org/publications/generative-ai-and-jobs-refined-global-index-occupational-exposureQ3: OECD publishing - IS GENERATIVE AI A GENERAL-PURPOSE TECHNOLOGY?https://www.oecd.org/content/dam/oecd/en/publications/reports/2025/06/is-generative-ai-a-general-purpose-technology_6c76e7b2/704e2d12-en.pdfQ4: NBER WORKING PAPER SERIEShttps://www.nber.org/system/files/working_papers/w31161/w31161.pdfQ5: IAB-REGIONAL Berichte und Analysen aus dem Regionalen Forschungsnetzhttps://doku.iab.de/regional/BB/2025/regional_bb_0125.pdfQ6: Rahmenlehrplan Industrieelektrikerhttps://www.ihk.de/blueprint/servlet/resource/blob/315230/a3e194f28d017d59fbd88fb1dc1b23dc/rahmenplan-industrieelektriker-in-data.pdfQ7: Bundesinstitut für Berufsbildung - Industrieelektriker/Industrieelektrikerin - Fachrichtung Betriebstechnik (Ausbildung)https://www.bibb.de/dienst/berufesuche/de/index_berufesuche.php/profile/apprenticeship/1311008https://www.paypal.com/donate/?hosted_button_id=9UW85PQWLBWZSAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Dr. Shuvro Roy and Dr. Amanda Piquet discuss a brief overview of stiff person syndrome, as well as the trial and the trial results.  Read more about this abstract on the AAN website.   Show transcript:  Dr. Shuvro Roy: Hi, this is Shuvro Roy from the University of Washington and welcome to today's Neurology Minute. I just wrapped a longer conversation with Amanda Piquet from the University of Colorado Anschutz School of Medicine. We were just talking about the recent Phase 2 trial evaluating Miv-cel Kyverna Therapeutics' anti-CD19 CAR T-cell therapy in patients with Stiff Person Syndrome. Amanda, would you mind taking us through a brief overview of SPS as well as the trial and their trial results? Dr. Amanda Piquet: So Stiff Person Syndrome, or SPS, is a rare disabling autoimmune neurologic disease with a major unmet need. About 80% of patients ultimately lose their mobility and we currently have no FDA approved therapies. Existing treatments like IVIG, rituximab, and plasmapheresis are all used off label, often requiring chronic dosing and frequently failing to stop progression. KYSA-8 is a registrational Phase 2 study of 26 patients with refractory SPS. Patients experienced rapid, statistically significant and clinically meaningful improvement across all primary and secondary endpoints. Primary endpoint was the timed 25-foot walk. And this improved by a median of 46% at 16 weeks. Of patients requiring walking aids at baseline, about two thirds no longer needed them by week 16 to complete that 25-foot walk. Some patients who had struggled to walk were even able to run again after treatment. Another key finding was that all patients discontinued chronic immune therapies and remained off treatment as of the last follow-up. From a safety standpoint, miv-cel was generally well tolerated, with no high grade CRS or ICANS observed. In my opinion, these outcomes are unlike anything we've seen previously with Stiff Person Syndrome and may represent a paradigm shift, not only for SPS, but potentially for other antibody-mediated neurologic diseases more broadly. Dr. Shuvro Roy: Just curious, are there any upcoming implications for the application of this treatment for patients, you think, in the coming year or so? Dr. Amanda Piquet: Kyverna, the company who developed miv-cel, has initiated a rolling BLA with the FDA for potential approval and this would be, if approved, the first CAR-T therapy for SPS. So we're anxiously awaiting the outcome of that process. Dr. Shuvro Roy: Fantastic. Amanda, thank you so much for your time. And if you are intrigued and want to know more details behind the findings in the study as well as a conversation around CAR-T therapy for autoimmune neurologic disease as a whole, I encourage you to check out the Neurology Podcast feed for our full conversation there. Thanks for tuning in.  

Dr. Shuvro Roy and Dr. Amanda Piquet discuss a brief overview of stiff person syndrome, as well as the trial and the trial results.  Read more about this abstract on the AAN website.   Show transcript:  Dr. Shuvro Roy: Hi, this is Shuvro Roy from the University of Washington and welcome to today's Neurology Minute. I just wrapped a longer conversation with Amanda Piquet from the University of Colorado Anschutz School of Medicine. We were just talking about the recent Phase 2 trial evaluating Miv-cel Kyverna Therapeutics' anti-CD19 CAR T-cell therapy in patients with Stiff Person Syndrome. Amanda, would you mind taking us through a brief overview of SPS as well as the trial and their trial results? Dr. Amanda Piquet: So Stiff Person Syndrome, or SPS, is a rare disabling autoimmune neurologic disease with a major unmet need. About 80% of patients ultimately lose their mobility and we currently have no FDA approved therapies. Existing treatments like IVIG, rituximab, and plasmapheresis are all used off label, often requiring chronic dosing and frequently failing to stop progression. KYSA-8 is a registrational Phase 2 study of 26 patients with refractory SPS. Patients experienced rapid, statistically significant and clinically meaningful improvement across all primary and secondary endpoints. Primary endpoint was the timed 25-foot walk. And this improved by a median of 46% at 16 weeks. Of patients requiring walking aids at baseline, about two thirds no longer needed them by week 16 to complete that 25-foot walk. Some patients who had struggled to walk were even able to run again after treatment. Another key finding was that all patients discontinued chronic immune therapies and remained off treatment as of the last follow-up. From a safety standpoint, miv-cel was generally well tolerated, with no high grade CRS or ICANS observed. In my opinion, these outcomes are unlike anything we've seen previously with Stiff Person Syndrome and may represent a paradigm shift, not only for SPS, but potentially for other antibody-mediated neurologic diseases more broadly. Dr. Shuvro Roy: Just curious, are there any upcoming implications for the application of this treatment for patients, you think, in the coming year or so? Dr. Amanda Piquet: Kyverna, the company who developed miv-cel, has initiated a rolling BLA with the FDA for potential approval and this would be, if approved, the first CAR-T therapy for SPS. So we're anxiously awaiting the outcome of that process. Dr. Shuvro Roy: Fantastic. Amanda, thank you so much for your time. And if you are intrigued and want to know more details behind the findings in the study as well as a conversation around CAR-T therapy for autoimmune neurologic disease as a whole, I encourage you to check out the Neurology Podcast feed for our full conversation there. Thanks for tuning in.  

En el programa El Remate de La Diez Capital radio dentro de su espacio de análisis político internacional, interviene el profesor, Eduardo Pintado. Marruecos mata a un alto dirigente del Polisario en un ataque con drones en el Sáhara. Lahbib Abdelaziz, hijo del expresidente saharaui Mohamed Abdelaziz, estaba considerado como líder de futuro para el movimiento independentista. Lehbib Mohamed Abdelaziz, el cuarto de los siete hijos del líder histórico del Frente Polisario, Mohamed Abdelaziz (1948-2016), ha muerto junto con otros "dos combatientes" por el ataque de un dron de Marruecos, ha informado una fuente saharaui a RTVE Noticias. La fuente ha señalado que, pese a que todavía no se ha desvelado la versión oficial de los hechos, los tres perdieron la vida el domingo por el ataque de un dron marroquí junto al muro militar que divide el Sáhara Occidental. El Ministerio de Defensa Nacional, citado por la agencia de prensa saharaui (SPS), ha destacado que Lehbib Mohamed Abdelaziz pereció mientras "dirigía acciones combativas contra posiciones de las fuerzas de ocupación marroquíes" junto al muro.

Dartmoor is famous for its semi-wild hill ponies that roam across the moorland. But concerns have been raised by the Dartmoor Hill Pony Association that new agri-environment schemes will require such a steep drop in the numbers of grazing livestock in the area that up to 93 percent of the ponies will be lost. We hear from the association's Secretary, Joss Hibbs.Next year will be the last that farmers in England receive direct subsidy payments, based on how much land they farm. Direct payments have been particularly important for upland farmers in areas like the Lake District, where they are now being replaced by environmental schemes. Caz Graham speaks to two generations of a Lake District farming family about the continued viability of upland farming.The Government has published fresh guidance this week for farmers and food businesses to help them prepare for the new sanitary and phytosanitary - or SPS - agreement between the UK and the European Union, which is expected to be brought in in around a year's time. The Government says the SPS agreement will make it easier for British farmers to sell into the EU, but it could also mean a change in the agro-chemicals farmers can legally use on their crops, and if the rules change suddenly, there are concerns farmers could be left with crops grown under the old rules, which they could no longer sell under the new rules. UK peatlands - an important habitat for wildlife and a major carbon sink - are facing pressure from development, intensive land use and a changing climate, with around 80% believed to be degraded. In Wales however, the National Peatland Action Programme has completed over three and half thousand hectares of restoration work since 2020. In the Cambrian Mountains the project has been so successful that water voles have arrived in the area. A study out this week from Lantra - a charity which provides training and qualifications in land-based industries - says that there are jobs in farming, fishing and forestry that are not being filled because of a so-called 'skills squeeze'. This comes a week after a much-discussed report, commissioned by the government, which found that job opportunities for young people are shrinking, with one million classed as NEETS - not in education, employment or training. We ask if land-based work is part of the solution.Presented by Charlotte Smith and produced by Jo Peacey. A BBC Audio Bristol production.

We love to hear from our listeners. Send us a message.In episode 130 of Cell & Gene: The Podcast, Dr. Naji Gehchan, Chief Medical and Development Officer at Kyverna Therapeutics, joins Host Erin Harris to outline the company's mission to apply CAR T-cell therapy beyond oncology to treat severe autoimmune diseases, highlighting promising Phase 2 data from its investigational therapy, Miv-cel, in stiff person syndrome (SPS). Dr. Gehchan explains that Miv-cel works by deeply depleting pathogenic B cells and enabling a broad immune reset, differentiating it from conventional therapies that require ongoing management. As Kyverna advances a rolling BLA submission, Dr. Gehchan positions this milestone as potentially historic, both for SPS patients and for the broader cell therapy field, signaling an inflection point where CAR T could transform autoimmune disease care in the same way it has oncology.Subscribe to the podcast!Apple  |  Spotify |  YouTubeVisit my website: Cell & GeneConnect with me on LinkedIn

The government has published fresh guidance for farmers and food businesses to help them prepare for the new sanitary and phytosanitary - or SPS - agreement between the UK and the EU. It's expected to take effect in a year's time. It's supposed to make trade easier, with fewer checks and less paperwork, but there are still many points in the agreement to iron out. Peatlands are one of the most valuable sources of carbon storage and they provide important habitats for wildlife and plants too. Across Wales the National Peatland Action Programme is working to improve these precious sites. In the Cambrian Mountains the project has been so successful that water voles have now populated the area. All week we're assessing the state of upland farming across the UK. In Scotland, 70% of agricultural land is classed as uplands. Most of those farms have sheep, many also have beef cattle and forestry is also a big part of Scottish farming. Agriculture is devolved and the Scottish government has, until now, held onto the direct payments which existed under the pre-Brexit EU system. That's being phased out, and upland farmers are concerned that under the new rules they could lose out. Presenter = Anna Hill Producer = Rebecca Rooney

Surrey Police Board Chair steps down after Lipinski's departure as chief (0:39) Harley Chappell, former Chair of the Surrey Police Board Lipinski out as Surrey's police chief: what does this mean for the SPS? (29:40) Darin Sheppard, Vice President of the Surrey Police Inspectors Association Climate change and a strong El Nino: could 2027 be the hottest year yet? (43:37) Kristi Gordon, Senior Meteorologist for Global B.C. Learn more about your ad choices. Visit megaphone.fm/adchoices

Lipinski out as Surrey's police chief: what does this mean for the SPS? Darin Sheppard, Vice President of the Surrey Police Inspectors Association Learn more about your ad choices. Visit megaphone.fm/adchoices

(4) Bob Zimmerman recounts how, during the critical Lunar Orbit Insertion, the crew fired the SPS engine behind the moon with no communication and no backup; failure meant certain death. Upon arrival, the astronauts were initially disappointed by the moon's skull-like, colorless appearance, comparing it to a barren sandbox. However, the guest notes that their observations settled a decades-old scientific debate by confirming that lunar craters were the result of impacts rather than volcanic activity. This successful orbital maneuver demonstrated the power of the Saturn 5 to reach anywhere in the solar system, mirroring modern goals for space settlement.1940 GODDARD AT ROSWELL

Oh ho ho well if it isn't probably the 4th or 5th time I've started an episode description out with “Oh ho ho”. It's weird because I do not talk like this in real life. I've probably never said those words in that order in my whole life. But there's something about putting pen to paper that really brings out my “silly side”. And if you like silly, you're gonna love this episode of YKS, which at its peak recorded over 3.2 SPS (sillies per second)! Now that's a lot of sillies! But today's Kickstarter campaigns are deadly serious: consider, for instance, a device that allows pets to go outside. What sinister mind…ah! Perish the thought. Just download and enjoy all that and more on today's YKS!Music for YKS is courtesy of Howell Dawdy, Craig Dickman, Mr. Baloney, and Mark Brendle. Additional research by Zeke Golvin. YKS is edited by Producer Dan. Social Media by Maddalena Alvarez.Executive Producer Tim Faust (@crulge)Want this episode ad-free? In addition to many hundreds of other things as well? Then it's YKS Premium for you! Sign up today to support the show with the cleanest (by our standards!!!) feed around.Follow us on Instagram: @YKSPod, TikTok: YourKickstarterSucks and subscribe to our YouTube channel for more video stuff! Wow, 2026 is gonna be lit!! Gift subscriptions to YKS Premium are now available at Patreon.com/yourkickstartersucks/giftSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Craft   Nick Pollack and special guest Eno Sarris look at the the most added SPs in fantasy. Nick Pollack | Eno SarrisJoin The Discussion | PL+ and PL Pro Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Craft   Nick Pollack and special guest Eno Sarris look at the the most added SPs in fantasy. Join Our Discord & Support The Show: PL+ | PL Pro - Get 15% off Yearly with code PODCASTProud member of the Pitcher List Fantasy Baseball Podcast Network Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

O comércio internacional nunca é apenas sobre oferta e demanda. No sistema internacional contemporâneo, tarifas, barreiras sanitárias e fluxos de commodities também funcionam como instrumentos de poder, proteção econômica e pressão diplomática. Neste episódio do Atualiza e Revisa, Luiza Bringel analisa o avanço das exportações brasileiras de carne bovina para a China, a nova política tarifária chinesa e os embargos sanitários aplicados a frigoríficos brasileiros em 2026. Mais do que discutir agronegócio, o episódio mostra como comércio, geopolítica, OMC e diplomacia econômica estão profundamente conectados. Você vai entender: • Como funciona o sistema de cotas tarifárias imposto pela China à carne bovina brasileira • A diferença entre barreiras tarifárias, barreiras não-tarifárias e instrumentos de defesa comercial • O que são medidas sanitárias e fitossanitárias (SPS/MSF) e por que elas geram disputas na OMC • A distinção entre os acordos SPS e TBT da Organização Mundial do Comércio • O conceito de neoprotecionismo e o uso político do sanitarismo no comércio global • Como a dependência do mercado chinês expõe vulnerabilidades estruturais da pauta exportadora brasileira • O papel da COSBAN, do MAPA e da diplomacia comercial brasileira nas negociações com Pequim • Como o tema se conecta à reprimarização da economia e à assimetria comercial Brasil-China Além disso, o episódio conecta comércio internacional, política externa brasileira, economia política internacional e geografia agrária, sempre com foco no nível de aprofundamento exigido pelo Instituto Rio Branco.

Today I do some number swapping, some late night metal detecting, and I talk to an entire family of psycho bitches. This show is all thanks to Billio Dillio and the billions of others who support my shows on Patreon and Spotify and Tim Apple. The opening song is by BarberShopJon on Fiverr. The background music is Black Mages by Emergency Pizza Party. The end song is Wheels by Ghost Rappy. You know, I just watched a trailer for La Brea and it looks kind of cool. I doubt I'll ever watch it, but I would probably like it if I did.LEARN MORE ABOUT THE SHOW: To find out more about the music you hear on this show, visit our page of artists. For a bit of history and a studio tour, this is a good starting page. Request a prank call and find links related to shows at snowplowshow.com. If you're searching for a specific thing said in a show, shitbradsays.com is a great resource for that.SUPPORT THE PLA: For extra weekly shows, subscribe on Patreon, Spotify, or Apple. Get our t-shirts and stickers at our TeePublic store. Get coins, vinyl records, CDs, and more on our Bandcamp page. We also have thing in our Zazzle store in our Spreadshirt store. Buy important things for us at PLA's wishlist or Brad's wishlist, but most importantly, please tell your friends, family, and strangers about all about us.JOIN THE COMMUNITY: Add PLA on Prankcast for live shows, add PLA on Facebook, add Snow Plow Show on Facebook, add PLA on X, add PLA on Tik Tok, add PLA on Bluesky, add PLA on Tumblr, add PLA on YouTube, add Snow Plow Show on YouTube, PLA on Twitch, PLA on Instagram, join a Prank Call Discord, the PLA Reddit, add RBCP on Instagram, add RBCP on X, add RBCP on YouTube, and leave a voice message for the show at 814-422-5309.PLA FRIENDS AND STAFF: Nik Caesar from scary-art.com is the unofficial PLA artist.  Buy PLA designs from Nik's Spreadshirt store.  You might also like the cactus and PLA designs in Laugh Track Matt's store.  Clownsec does a lot of cool things for PLA so go honk the PLAnet.  Watch JIAD's Calls of Mass Confusion and listen to a few of the prank call shows over at World of Prank Calls. Joe DiVita and Vista Blue do lots of music for us, but so do lots of other people, so visit the SPS music page for a very incomplete list.GAME WITH PLA Join us Animal Crossing addicts by becoming our friends on Switch. If you're into GTA5, join the PLA Radio crew.

Todd Conklin and Bob Edwards discuss Solutions for Patient Safety (SPS), a grassroots movement of learning teams that used operational learning to dramatically reduce harm in pediatric care. The episode covers emotional stories from the SPS meetings, practical methods like soak time and learning teams, the power of continuous improvement, and the real-world impact of saving thousands of young lives.

The Climate Change Committee has published a new report about the consequences of a 2% rise in global temperatures and what the UK needs to do about it. The CCC, which reports to UK government on adapting to climate change, says that by 2050, 92% of homes are likely to overheat, peak river flows will be up to 45% higher, and water supply shortfalls could exceed five billion litres per day. It points out that the cost of doing nothing is far greater than acting now, and it proposes investment of around £11 billion a year, split evenly between public and private funding. We ask what it means for farmers.The prospect of closer ties with the European Union continues to make political headlines, and farmers are watching closely as the government works towards EU re-alignment and a new sanitary and phytosanitary or SPS agreement which should ease trade in food and agricultural goods between the UK and the EU. The House of Lords European Affairs Committee has been hearing what an SPS agreement could mean for farmers, the meat industry and ports.All week we're celebrating British flowers - locally grown flowers account for a tiny fraction of the UK market even though we spend some 2.2 billion pounds on cut flowers. We visit a flower grower who is trying to change that, connecting local producers and florists and promoting home-grown flowers via the South Yorkshire Flower Hub.Presenter = Anna Hill Producer = Rebecca Rooney

SPS to close one if its alternative high schools, Boeing ordered to pay nearly $50 million to family of crash victim, and you may be able to watch the World Cup from a "floating pitch" in Seattle. It’s our daily roundup of top stories from the KUOW newsroom, with host Patricia Murphy. We can only make Seattle Now because listeners support us. Tap here to make a gift and keep Seattle Now in your feed. Got questions about local news or story ideas to share? We want to hear from you! Email us at seattlenow@kuow.org, leave us a voicemail at (206) 616-6746 or leave us feedback online.See omnystudio.com/listener for privacy information.

VOV1 - 4 tháng đầu năm, Việt Nam xuất khẩu nông lâm thuỷ sản đạt hơn 23 tỷ USD. Mặc dù đạt mức tăng trưởng 5,4%, các ngành hàng của Việt Nam vẫn đứng trước nhiều nguy cơ, thách thức từ các quy định quốc tế và các đối tác lớn.Thông tin được Bộ Nông nghiệp và Môi trường đưa ra tại Hội nghị “Cập nhật phổ biến thông tin các quy định về an toàn thực phẩm và kiểm dịch động, thực vật trong Hiệp định Đối tác Kinh tế Toàn diện Khu vực (RCEP) và Nghị định số 280 của Trung Quốc", tổ chức tại Đắk Lắk sáng nay (14/5).Hội nghị “Cập nhật phổ biến thông tin các quy định về an toàn thực phẩm và kiểm dịch động, thực vật (SPS) trong Hiệp định Đối tác Kinh tế Toàn diện Khu vực (RCEP) và Nghị định số 280 của Trung Quốc" được tổ chức bằng hình thức trực tiếp tại Đắk Lắk và trực tuyến đến 34 điểm cầu tại văn phòng Bộ Nông nghiệp và Môi trường cùng các tỉnh, thành phố trong cả nước.Trong 4 tháng đầu năm, kim ngạch xuất khẩu nông, lâm, thủy sản của Việt Nam ước đạt hơn 23 tỷ USD, tăng 5,4%. Trong đó, nhóm nông sản tăng 1,5%; sản phẩm chăn nuôi tăng mạnh nhất ở mức 45,5%; thủy sản tăng gần 12%.Thứ trưởng Bộ NN&MT Võ Văn Hưng nêu giải pháp để nông sản Việt Nam đáp ứng các tiêu chuẩn quốc tế.

Matt Olson, Parker Messick, Foster Griffin, Michael McGreevyAJ EwingHistorical CLQ Data95 people have played in the CLQ all 3 yearsOf that 13 have an average of over 60% of the total points across the 3 seasonsChampions League Aaron Jones - Still 1st at 108 pointsReally solid across the boardAndrew Geller - Up to 2nd at 99.5 pointsSpending his FAAB - Down to $309Michael Hughes - 3rd at 99 pointsWent out and got Killian & Graham Ashcraft for saves and added Jesus RodriguezMichael Brophy - 4th at 98 (up 5 this week)Still sitting on $773 in FAABBob Catsioroumpas - 5th at 94.5Ricky Zito - 6th at 90In week 1 took a 0 from Teel and Tolle, as he had 5 other stashes (Crews, Kristian Campbell, Seiya, Logan Henderson, Trey Yesavage) and came out of the draft with only 3 SPs with rotation spots (Skenes, Crochet, Sasaki)⁠⁠⁠PullHitter merch is here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Welcome to the PullHitter Podcast, your destination for actionable resources and tools to grind your way to ultimate fantasy baseball success.Support my work and join the Pull Hitter Patreon:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/user?u=32383693&utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=creatorshare_creator&utm_content=join_link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on twitter: @pullhitterpod ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/PullHitterPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Email : pullhitterpodcast@gmail.com Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠pullhitter.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My link tree with all of my links in one spot:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/pullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Also check out me cohosting the Launch Angle Podcast with Rob Silver!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://anchor.fm/robe⁠⁠

SPS superintendent says district could be insolvent as soon as next year, sexual abuse investigations mishandled at Tacoma ICE lockup, UW report finds, and World Cup hotel bookings are falling short of expectations. It’s our daily roundup of top stories from the KUOW newsroom, with host Paige Browning. The interview in today's episode was produced by John O'Brien. We can only make Seattle Now because listeners support us. Tap here to make a gift and keep Seattle Now in your feed. Got questions about local news or story ideas to share? We want to hear from you! Email us at seattlenow@kuow.org, leave us a voicemail at (206) 616-6746 or leave us feedback online.See omnystudio.com/listener for privacy information.

Arsenal are 3 points clear of the chasing pack again, after hard fought winat home to Newcastle despite their best efforts to raise the Arsenal fanbases collective blood pressure!  Join Gabby and Coach for a SPS review of an extremely pressured & joy inducing Arsenal win.LOCK IN!

An airhacks.fm conversation with Christofer Dutz (@christofer-dutz) about: discussion about Apache PLC4X as the JDBC of industrial automation, the API and SPI architecture with Java service loader for driver discovery, Modbus protocol for HVAC systems and heating devices, PLC4X core API operations including discovery and browsing and reading and writing and subscribing and publishing, multi-language support with PLC4J for Java and PLC4Go for Go and PLC4Py for python and C#, code generation from protocol definitions using language-specific templates, XML-based cross-language unit tests, OPC UA as the Esperanto of industrial protocols versus PLC4X speaking native device protocols, OPC UA overhead causing PLC strain and network congestion, comparison of OPC UA to CORBA and grpc, CORBA IIOP protocol on devices, bidirectional communication for reading sensor data and writing control flags, subscription-based event-driven data collection to reduce PLC polling load, founding ToddySoft to provide commercially supported open source industrial products, the gap between open source libraries and industrial consumption, ToddySoft Connect as bubble-wrapped PLC4X drivers for platforms like Inductive Automation Ignition, eliminating edge gateway boxes on shop floors, native protocol communication reducing network load on 100 Mbit industrial networks, unified namespace concept as JMS for industrial automation, Apache IoTDB as time series database with push queries and callback features, Apache TsFile storage format for writing time series data directly on PLCs, shifting from polling to pushing in industrial data collection, ToddySoft File as C libraries compiled for PLCs, ToddySoft DB as embedded stripped-down IoTDB for edge devices, ToddySoft Edge as the combined platform resembling an application server for industrial automation, Industry 4.0 definition and evolution from manual labor through steam power through PLC automation to connected production, compressed air as a service business model, early failure detection in multi-step production lines, OSGi runtime driver loading, Eclipse Tycho build system difficulties, Kafka Connect PLC connectors, SPS fair in Nuremberg as one of the largest industrial automation fairs, signal theory and Nyquist sampling rate in PLC polling Christofer Dutz on twitter: @christofer-dutz

In this episode of The Lebanese Physicians Podcast, I sit down with Dr. Zakia Dimassi, a leader in medical education at Khalifa University, to explore an often overlooked issue in simulation-based training: fatigue in standardized patients (SPs). Drawing from her recent publication in Clinical Simulation in Nursing, Dr. Dimassi sheds light on how physical, cognitive, and most importantly emotional fatigue impacts SP performance, assessment accuracy, and ultimately the quality of medical education. Together, we discuss: Why fatigue can begin as early as 30 minutes into sessions How emotional roles (e.g., breaking bad news) take the greatest toll The implications for OSCE reliability and high-stakes exams Real-world observations of performance lapses and scoring variability Practical solutions: better scheduling, breaks, SP-centered design, and de-rolling techniques The future role of AI and hybrid simulation models in reducing fatigue

In today's episode, Laurie and George dive deep into the world of the sexual pursuer. They explore the underlying attachment and connection needs of the sexual pursuer and help SPs develop emotional regulation and language around expressing these needs. If you identify as an SP in your cycle and struggle with rejection or disconnection this episode is for you to learn how to; self-soothe and invite your partner into your world. We take care in this episode not to pathologize or diagnose the needs of the SP but to help couples engage in compassionate and effective communication. Intimacy is a shared world between lovers, where tangible attachment is created. If this sounds like you make sure to download and listen to this show! Our book, Brave Love, Great Sex is now available for pre-order on Amazon. Secure your copy today! Learn more about your ad choices. Visit megaphone.fm/adchoices

4. Zimmerman focuses on Apollo 8 reaching lunar orbit using the critical SPS engine. He details the crew's first close-up views of the moon, which they described as a desolate, cratered "sandbox". These human observations settled scientific debates, proving the lunar surface was shaped by impacts. (4)

Need help mapping out your first book? Download your free 1-Page Book Launch Plan here: https://publish.selfpublishing.com/one-page-launch-plan/?last_touch_channel_new=Social&last_touch_medium=Youtube%20-%20Feed&final_touch_lead_source=One%20Page%20Book%20Launch%20PlanThousands of first-time authors have already turned their ideas into bestselling books with our guidance. You could be next. http://selfpublishing.com/work-with-usMost self-published authors are leaving thousands of dollars on the table every single month. There is a little known strategy that turns your book into a one-to-many revenue engine that builds your authority, grows your audience, and brings in paying customers. Coaches, consultants, and experts who have figured this out are landing speaking gigs, booking podcast interviews, and scaling their business faster than ever. If writing a book has always been on your list, this video will show you exactly why now is the time to make it happen.Popular Free Resources:Nonfiction Book Outline Template: https://publish.selfpublishing.com/nonfiction-outline-template/?utm_source=instagram&utm_medium=social&utm_campaign=default-linktree&last_touch_channel_new=Social&last_touch_medium=Form+EmbedFiction Book Outline Template:  https://publish.selfpublishing.com/fiction-outline-template/?utm_source=instagram&utm_medium=social&utm_campaign=default-linktree&last_touch_channel_new=Social&last_touch_medium=Form+EmbedNeed help mapping out your first book? Download your free 1-Page Book Launch Plan here: https://publish.selfpublishing.com/one-page-launch-plan/?last_touch_channel_new=Social&last_touch_medium=Youtube%20-%20Feed&final_touch_lead_source=One%20Page%20Book%20Launch%20PlanFollow selfpublishing.comYoutube https://www.youtube.com/@selfpublishingcomInstagram https://www.instagram.com/selfpublishingcom/TikTok https://www.tiktok.com/@selfpublishingdotcomFacebook https://www.facebook.com/selfpublishingcomFollow Chandler BoltInstagram https://www.instagram.com/realchandlerbolt/TikTok https://www.tiktok.com/@realchandlerboltLinkedin https://www.linkedin.com/in/chandlerbolt/Facebook https://www.facebook.com/chandler.bolt1Here are some links that might come in handy:Apply for a free book consultationRegister for our free on-demand trainingMust-watch episodes:SPS 044: Using A Free + Shipping Book Funnel with Anik SingalSPS 115: Using Atomic Habits To Write & Publish A Book with James ClearSPS 127: Traditional vs. Self Publishing: Which You Should Choose with Ruth Soukup SPS 095: The Five Love Languages: Selling 15 Million Copies with Gary ChapmanSPS 056: How I Sold 46M Copies of My Self Published Book with Robert Kiyosaki

Dobrodošli u novu, 28. epizodu podkasta! Nedelja za nama donela je ozbiljne političke potrese, ulične barikade i regionalne medijske šamare. U ovoj epizodi prečešljali smo sve najvažnije teme koje trenutno kroje našu stvarnost: od bolničke postelje Ivice Dačića i pitanja koliko to slabi mašineriju SPS-a pred izbore, preko bagera na beogradskom Ušću gde država gura akvarijum od 90 miliona evra, dok građani telima brane park. Pričali smo i o pravoj seljačkoj buni – poljoprivrednici ne odustaju od blokada dok se bore za goli opstanak, ali i o situaciji koja se nadvija nad redakcijama medija poput „N1”, „Nove” i „Danasa” pod novom komandom. Poseban osvrt dali smo na to kako su institucije u Crnoj Gori i Bosni i Hercegovini rekle „dosta” i ugasile signal medijskoj imperiji Željka Mitrovića u regionu, dok je kod vladika bihaćko-petrovački Sergije otišao korak dalje u prošlost i zabranio savremeni srpski jezik u crkvi zbog „nesrećnog Vuka Karadžića”. Za sam kraj, analiziramo hapšenje Ace Đukanovića u Nikšiću i pitamo se – hoćemo li mi ikada doći do naših „nedodirljivih”? Za sam kraj, veliko iznenađenje za sve ljubitelje poezije mitropolita Fotija.

What’s Trending: Lakewood becomes the latest city to ban public drug use, Democrats continue to advocate for criminals and more mass layoffs at Amazon. // SPS wants to replace Memorial Stadium and also fix its massive budget shortfall. // An Auburn dog attack victim is suing King County.

The meat industry say increased charges for Food Standards Agency staff such as abattoir vets and inspectors could threaten some operations. New charges come into force at the end of this month, and the hourly rate for some services will be more than 20% higher. The Food Standards Agency says a global vet shortage means it is having to pay more to recruit and retain them, and there are other inflationary pressures across the sector. We speak to the Association of Independent Meat Suppliers. Food producers, manufacturers, importers and exporters are all being asked to get prepared early for the new trading system under the EU/UK Trade Agreement, which is expected to come in next year. The new agreement will include a relaxation of the food biosecurity paperwork, known as SPS or Sanitary and Phytosanitary rules. The International Chambers of Commerce say this is good news. And trade disruption caused by the war in the Middle East has pushed oil and fertiliser prices up. Farmers here are worried there could be shortages of imported fertiliser. With this in mind, some farmers are looking at ways of mitigating the situation. David Morgan keeps a large herd of beef cattle at Peterchurch in Herefordshire's Golden Valley. He's invested in slurry separating equipment to help produce better home grown fertiliser.Presenter = Anna Hill Producer = Rebecca Rooney

In this episode of Inside the SCCA, I sit down with rising racing talent Asad Nikadambaev, who stunned the field at Buttonwillow Raceway by taking victory in Spec Racer Ford Gen3 against some of the most experienced drivers in the class.Asad's journey started the way many modern drivers do — karting, sim racing, and relentless practice on the sim — but his rise through the ranks has been incredibly fast. In this interview we dive into:• How he went from karting at 10 years old to winning national races at 15• Why Spec Racer Ford is one of the best development platforms in motorsports• How sim racing helped him stay calm under pressure• The story behind the viral racing videos he makes with his sister• His goal of reaching GT racing, IMSA, and beyondIf you want to understand how young drivers climb the motorsports ladder, this episode gives you a rare look inside the mindset, preparation, and family support behind a rising racing career.And yes… he held off multiple national champions to do it.

Arsenal are SEVEN points clear of the chasing pack again, after a scrappy and hard fought win away at the AMEX, despite Fabian Hurzeler's incessant whining. Join Gabby and Deen for an extremely attractive SPS review of an extremely ugly & joy inducing Arsenal win.LOCK IN! 

In this Hobosode I see what's left on the car ding voicemails and call all of the numbers, just to see who will pick up. In the end I don't fool any new people, but I have a nice reunion with a few of the old ones and I'm able to completely empty all of the voicemails from last Dingtember. Thanks, Raising Kane, for sponsoring this one. The opening song is by Henrik. The background music is Switch Lanes by Emergency Pizza Party. The end song is yamiga69 by Jeff.LEARN MORE ABOUT THE SHOW: To find out more about the music you hear on this show, visit our page of artists. For a bit of history and a studio tour, this is a good starting page. Request a prank call and find links related to shows at snowplowshow.com. If you're searching for a specific thing said in a show, shitbradsays.com is a great resource for that.SUPPORT THE PLA: For extra weekly shows, subscribe on Patreon, Spotify, or Apple. Get our t-shirts and stickers at our TeePublic store. Get coins, vinyl records, CDs, and more on our Bandcamp page. We also have thing in our Zazzle store in our Spreadshirt store. Buy important things for us at PLA's wishlist or Brad's wishlist, but most importantly, please tell your friends, family, and strangers about all about us.JOIN THE COMMUNITY: Add PLA on Prankcast for live shows, add PLA on Facebook, add Snow Plow Show on Facebook, add PLA on X, add PLA on Tik Tok, add PLA on Bluesky, add PLA on Tumblr, add PLA on YouTube, add Snow Plow Show on YouTube, PLA on Twitch, PLA on Instagram, join a Prank Call Discord, the PLA Reddit, add RBCP on Instagram, add RBCP on X, add RBCP on YouTube, and leave a voice message for the show at 814-422-5309.PLA FRIENDS AND STAFF: Nik Caesar from scary-art.com is the unofficial PLA artist.  Buy PLA designs from Nik's Spreadshirt store.  You might also like the cactus and PLA designs in Laugh Track Matt's store.  Clownsec does a lot of cool things for PLA so go honk the PLAnet.  Watch JIAD's Calls of Mass Confusion and listen to a few of the prank call shows over at World of Prank Calls. Joe DiVita and Vista Blue do lots of music for us, but so do lots of other people, so visit the SPS music page for a very incomplete list.GAME WITH PLA Join us Animal Crossing addicts by becoming our friends on Switch. If you're into GTA5, join the PLA Radio crew.

In this episode, Brendan and Hunter sit down with O&P Insight's Vice President and General Manager Lesleigh Sisson, CFo, CFm, to discuss the rising trends in payer audits, the most common causes of avoidable revenue loss, and the proactive compliance strategies that help O&P clinics ensure claims not only get paid—but stay paid.Learn more about O&P Insight and connect with Lesliegh on Linkedin. Many thanks to Trulife for sponsoring this episode! Introducing the A-Pace—an innovative AFO designed for individuals with mild to moderate foot drop, with or without foot spasticity, weak muscles, or calf muscle loss, serving both unilateral and bilateral patients across low to high activity levels. Built with lightweight carbon fiber and a customizable trim-to-fit foot plate, the A-Pace reduces SKUs while offering comfort and ease of use with its anterior style and two magnetic closures. PDAC verified under codes L1932 and L1933, the A-Pace is available now at SPS.SPS Update: On the latest episode of SPS Unpacked, we unboxed the PROTEOR Kinterra EVAQ8. This innovative foot combines hydraulic articulation with vacuum suspension to deliver enhanced mobility and limb health. Click here to learn more!Visit spsco.com

Send a textWhat happens when a movement-first profession steps into a simulation lab built for physiology and decision-making under pressure? We sit down with Denise Romano, an assistant professor leading physical therapy simulation at Binghamton University, to unpack how PT learners can safely practice high-stakes mobility long before they enter acute care. From AFib in the ICU to COPD patients whose vitals shift during transfers, Denise maps out realistic scenarios that force students to balance safety, lines and tubes, and evolving clinical data while communicating clearly as a team.We walk through a full landscape of PT-focused simulations: early infection control adapted from nursing with Glow Germ, mobility checkoffs in hospital-like spaces, ventilator cases requiring careful progression, and standardized patient interviews for differential diagnosis. Denise explains why PT relies heavily on SPs for authentic movement, where mannequins still shine for physiologic fidelity, and how thoughtful debriefs convert messy moments into durable clinical judgment. Her use of entrustability scales tied to EPAs gives faculty a shared framework to chart each learner's path from novice to entry-ready clinician, with formative feedback that guides safer practice.The conversation also tackles the big barrier: unlike nursing, PT lacks the large-scale evidence to replace a portion of clinical hours with simulation. Denise makes a compelling case for a multi-site study to unlock that recognition, particularly as acute care placements tighten and risk tolerance narrows. She also shares a favorite classroom memory that turned a tangled SCD mistake into a lifelong safety cue, highlighting why simulated missteps are often the most memorable teachers. If you care about physical therapy education, clinical placements, competency assessment, or the future of healthcare simulation, you'll leave with concrete ideas and renewed urgency to give PT a stronger seat at the table.Subscribe for more conversations on simulation, clinical education, and the skills that move patient care forward. Share your thoughts, leave a review, and tell us which PT competencies you think simulation should tackle next.Innovative SimSolutions.Your turnkey solution provider for medical simulation programs, sim centers & faculty design.

For more than a decade, CAR-T therapy has been the miracle of oncology, turning end-stage blood cancers into curable diseases. But the application of these engineered cell therapies is expanding to reset the immune system for patients living with lupus, stiff person syndrome and other autoimmune conditions. And with new frontiers come new rules. In this week’s episode of "The Top Line," Fierce Pharma’s Angus Liu chats with Harpreet Singh, M.D., chief medical officer at Precision for Medicine and a former director of the FDA's Division of Oncology, about a recent article by FDA officials led by CBER Director Vinay Prasad, M.D., laying out the agency’s perspective on its regulation of autoimmune CAR-T therapies. Singh discusses how the agency’s "case-by-case" approach, as indicated in the article, could be similar to—and different from—CAR-T for oncology indications. She also talks about how drug developers should follow existing development experience, as well as prepare for specific requirements for long-term patient follow-up and potential new clinical endpoints from the agency. To learn more about the topics in this episode: FDA signals tailored approach to ‘carefully shepherd’ CAR-T therapy for autoimmune diseases Kyverna gains clear view to first CAR-T approval for autoimmune disease after 'truly remarkable' SPS readout Cabaletta CAR-T wipes out B cells without preconditioning in small autoimmune trial See omnystudio.com/listener for privacy information.

Welcome back to the People's Guild.In this episode, we're joined by @azircon and @davemccoy for a candid, wide-ranging conversation following the Escalation pre-sale. With 313K packs sold and 100 million SPS raised, the numbers speak loudly — but the real value of this discussion lies in what comes next.We dig into pricing strategy, community sentiment, governance dynamics, legacy card value, land utilization, onboarding friction, and the broader challenge of building in Web3 while earning long-term trust. AZ brings sharp perspective, Dave brings clarity from the operator's seat, and together the conversation pushes into meaningful territory around decision-making, communication, and growth.It's reflective, direct, and forward-looking — exactly the kind of dialogue that helps shape what Splinterlands becomes next.Enjoy the show!

5pm: One million show up for Seattle Seahawks Super Bowl victory parade // SPS says skipping class for Seahawks parade will be an unexcused absence // Seahawks super fans get tattoos to commemorate Super Bowl win // The Norwegian Biathlete that Confessed to Cheating on His Girlfriend // Letters

HEADLINE: Arrival: Entering Lunar Orbit and the Grey World. GUEST AUTHOR: Bob Zimmerman. SUMMARY:Apollo 8 successfully enters lunar orbit using the SPS engine, allowing the crew to witness the moon's desolate, cratered surface and confirm its impact origins.

Send us a textFreedom doesn't always announce itself with trumpets. Sometimes it looks like a quiet walk past an optometrist's office, a cab ride that feels like a lifetime, and a choice that will cost you every family tie the group controls. We're marking Claire's 21st anniversary of leaving Scientology's International Headquarters—a date that, by eerie symmetry, lands on the 40th anniversary of L. Ron Hubbard's death, a milestone the organization still avoids acknowledging.We open up about the machinery that makes leaving feel like a sin: disconnection policies that weaponize love, “blows and recoveries” that rename escapes and kidnapping attempts as internal metrics, and the secret “door welded shut” approach to anyone fleeing Int Base. From forced divorces inside RTC to the Hole's coercive environment, we lay out how language, policy, and fear knit together into a durable cage. We also map the institution's obsession with rewriting history—editing Mary Sue, Nibs, and long-time insiders out of films and lectures to sanitize the past—while highlighting the independent sources that preserved the record, from Sarge's accounts in Going Clear to meticulous journalism.There's a tactical layer too. We break down how protests were anticipated and neutralized, how thought-stopping turns curiosity into a trigger, and why even a well-meaning conversation with declared SPs can implode a young member's standing overnight. For anyone on the fence, this is our harm-reduction guide: understand the risks before you engage, and know that questions have consequences in high-control systems. We also talk about healing—adrenal exhaustion, the simple miracle of sleep, and the way health returns when chronic stress recedes—because life after control isn't theoretical; it's better.If this story resonates, share it with someone who needs a map, subscribe for future deep dives into cult tactics and recovery, and leave a review so more people can find it. Your voice helps others find their way out.Support the showBFG Store - http://blownforgood-shop.fourthwall.com/Blown For Good on Audible - https://www.amazon.com/Blown-for-Good-Marc-Headley-audiobook/dp/B07GC6ZKGQ/ref=tmm_aud_swatch_0?_encoding=UTF8&qid=&sr=Blown For Good Website: http://blownforgood.com/PODCAST INFO:Podcast website: https://www.buzzsprout.com/2131160 Apple Podcasts: https://podcasts.apple.com/us/podcast/blown-for-good-behind-the-iron-curtain-of-scientology/id1671284503 RSS: https://feeds.buzzsprout.com/2131160.rss YOUTUBE PLAYLISTS: Spy Files Playlist: https://www.youtube.com/playlist?list=PLWtJfniWLwq4cA-e...

Gooners, that wasn't good. Actually, it was quite bad. Join Coach and Deen for the SPS analysis of Arsenal's 2-3 home loss to Manchester United. The lads discuss the old enemy, old narratives, and what the future might hold.Tap in!

Day 3 of 10 for the Smart Poker Study Podcast 10-year Anniversary!Celebrate with SPS: https://www.smartpokerstudy.com/10yearsShow Notes: https://smartpokerstudy.com/pod575

Feds to investigate four WA school districts over trans athletes, Gov. Ferguson wants to slash spending on climate change, and SPS skipped safety measures when rebuilding Rainier Beach High School. It’s our daily roundup of top stories from the KUOW newsroom, with host Paige Browning. We can only make Seattle Now because listeners support us. Tap here to make a gift and keep Seattle Now in your feed. Got questions about local news or story ideas to share? We want to hear from you! Email us at seattlenow@kuow.org, leave us a voicemail at (206) 616-6746 or leave us feedback online.See omnystudio.com/listener for privacy information.

The Gunners blew their chance to extend their lead at the top of the Premier League to 8 points after a lethargic and boring effort against an extremely depleted, defensive, and technically impressive Liverpool. There wasn't much to discuss from this one, but join Mitch and Deen for the SPS review of a rainy and cold night at The Emirates.Tap in!

5. Lunar Orbit Insertion and the Disappointment of the Moon's Surface. Bob Zimmerman discusses how on Christmas Eve, Apollo 8 approached the moon. The critical moment was Lunar Orbit Injection (LOI), requiring the firing of the Service Propulsion System (SPS) engine. This burn had to occur while the craft was behind the moon, resulting in a dramatic Loss of Signal (LOS) for Earth. Susan Borman particularly dreaded this moment because the SPS engine, which had no redundancy, was their only way into and out of lunar orbit. NASA believed firing the engine would clear any potentially problematic bubbles in the fuel lines, adding another risk. Once in orbit, the astronauts were visually disappointed, with Frank Borman describing the moon's surface as looking like a "skull" or a lifeless sandbox. Their direct observation settled the debate among scientists, confirming that the moon's craters were the result of impacts, not volcanic activity. 1962

8. The Trans Earth Injection, Lovell's Navigation Error, and the Successful Reentry. Bob Zimmerman discusses how the Trans Earth Injection (TEI) was the mission's second moment of highest risk, requiring the non-redundant SPS engine to fire on the backside of the moon to propel them back to Earth. Susan Borman had been most anxious about this burn, knowing failure meant certain death in lunar orbit. When they reacquired signal, Jim Lovell famously declared, "I want to report that there is a Santa Claus," signaling success. On the return journey, Lovell, the navigator, accidentally cleared the navigation data in the computer (the gimbal), causing the spacecraft to lose orientation. Lovell was forced to correct the craft's position by manually using a sextant and taking readings from stars like Rigel and Sirius, proving the value of the backup system. Finally, they successfully executed the complex "double skip trajectory" reentry at 25,000 mph, landing within three miles of the recovery ships, though the capsule temporarily flipped upside down. 1618