Podcasts about new center

June 4, 2026 ~ Paddy Lynch, owner of Dutch Girl Donut discusses their new location in The New Center which opens tomorrow, national donut day. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

The new Center for Global Pediatric Health, an initiative between the Robert J. Havey, MD Institute for Global Health and Ann & Robert H. Lurie Children's Hospital of Chicago, is building a global community committed to improving the health of children worldwide. In this episode, Drs. Colleen Fant and Sahera Dirajlal-Fargo, co-directors of the new center, discuss their goals for the center, their own journeys in global pediatric health as well as emerging trends and challenges in pediatric care worldwide.

Spiegel and Holmes discussed the Bears' selection of center Logan Jones in the second round of the NFL Draft.

Star Citizen Alpha 4.8 will provide players the opportunity to unlock blueprints permanently. Progression in Star Citizen is becoming clearer, and customization is picking up, but still several key systems are lacking. Today, I'm joined by streamer XeroState to discuss the growing reality of Star Citizen and how player choice is becoming real very quickly.Today's Guests:XerostateYouTube: https://www.youtube.com/@UCJBnfo-JfuLRW1-hcEQPKyQTwitch: https://www.twitch.tv/xerostateToC:00:00 Introductions03:00 Do You Wanna Fight for Xenothreat?09:45 Too Real Too Soon?19:30 Customization In-Game38:45 What's Going on with Reputation45:10 Are Blueprints the New Center?52:20 Was Item Recovery T0 A Good Idea?01:12:30 How is Ship Combat?01:24:20 Big PredictionsWatch on YouTube: https://www.youtube.com/playlist?list=PLvpiPXCO7OVJOlBIclW9tbpb2g29gur3ISupport This Podcast:Patreon Paypal Ko-FiFollow Space Tomato on social media:Website  Youtube  My Other YoutubeInstagram Twitter Facebook Discord

Juan and Tim's Friday rant covers a lot of ground, from Juan's TED takeaways on AI's unprecedented speed and what it means for humanity, to the uncomfortable shift data teams need to make: work and decisions are the point, not pipelines and gold layers. They dig into what Medallion Architecture 2.0 looks like (feedback loops, insights to action, agent governance), why organizational design theory applies directly to agent swarms, and what library science can teach us about the future data stack. The thread running through all of it: the humans who thrive in this moment won't be the ones who build the most, but the ones with taste.See omnystudio.com/listener for privacy information.

11:30am - Zach Jones and Derek Kramer discuss the faceoff stats for the Sabres and if a change needs to happen on the fourth line

Today, University of Utah Health opened their very first center for medical innovation. The 60,000 square foot, four-level, state-of-the-art facility is named in honor of James LeVoy Sorenson, and it's designed to help advance and accelerate medical research here in Utah. So what could that mean for you -- a potential patient? For more information, Maria Shiloas speaks with Mark Paul, executive director of the new center.

The regulatory landscape around climate policy is shifting, and many agencies are left with outdated tools to manage modern risks. The Federation of American Scientists' Center for Regulatory Ingenuity hopes to give them a clearer path, offering practical guidance, partnerships and support for innovative approaches. We'll talk through that mission with Dr. Hannah Safford, Associate Director of Climate and Environment at FAS.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the Christian life isn't about becoming something new, but learning to live like you already are?Most of us approach faith like a self-improvement project. Try harder. Do better. Climb toward holiness through sheer willpower. But Paul flips the script in Colossians 3. He says we've already been raised with Christ. Our identity is already secure, hidden with Christ in God, the most protected place in the universe. The real work isn't transformation through effort. It's learning to wear the new clothes that fit who we've already become.We explore the beautiful image of a wardrobe, drawing on C.S. Lewis's Narnia, where stepping through the wardrobe turns children into kings and queens. We look at how good things like careers, relationships, and success become dangerous when they become ultimate things. The Greek word epithumeia reveals that sin isn't just wanting bad things. It's wanting good things too much. And you can't defeat that through willpower. You need what Thomas Chalmers called "the expulsive power of a new affection." Only by falling more in love with Christ can we be freed from lesser loves. This isn't behavior management. It's heart transformation. Like turning a horse into a winged being.KEY INSIGHT: You don't need more willpower to change your life. You need a new center. Only a deeper love can expel a lesser one.

Mike Mulligan and David Haugh discussed the top sports stories of the day in the Pick 6 segment.

Hr 2 - Have the Titans already found their new center?See omnystudio.com/listener for privacy information.

Hr 2 - Have the Titans already found their new center?See omnystudio.com/listener for privacy information.

3/10/26 - The Lions sign a new center, Free Agent Frenzy, Two Grand Slam, Steve Yzerman

Leila Rahimi, Marshall Harris and Mark Grote were joined by former Patriots linebacker and Super Bowl champion Matt Chatham to share a scouting report on new Bears center Garrett Bradbury, whom Chicago acquired in a trade with New England.

The Bears need a new starting center after 27-year-old Drew Dalman suddenly retired. It was a stunning development that Dan Wiederer and Mark Grote talk through in this one. Did any of us see this coming? When did the Bears think this was possible? And how could the Bears replace him? To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

"We want the ones who's stealing the cars. We want the ones who's robbing. We want the ones who's failing with their schoolwork." That's what staff members at Teen Empowerment (TE) say about connecting with local young people. The nonprofit works alongside teens to foster peace, equity, and justice in the community. As reported by WXXI's Noelle Evans and Max Schulte, the center recently opened a new location at the corner of Magee and Dewey avenues — an area on Rochester's north side that has been the site of numerous deaths by gun violence in recent years. TE leaders say it an opportunity to offer young people a different pathway forward. This hour, we sit down with some of the teens and a Teen Empowerment leader to discuss their work, their goals, and what the new hub means for their mission. In studio: Shanterra Mitchum, program director at Teen Empowerment Sahiyra Dillard, program coordinator at Teen Empowerment Emerra Moore, Teen Empowerment participant Paul Ross Jr., Teen Empowerment participant ---Connections is supported by listeners like you. Head to our donation page to become a WXXI member today, support the show, and help us close the gap created by the rescission of federal funding.---Connections airs every weekday from noon-2 p.m. Join the conversation with questions or comments by phone at 1-844-295-TALK (8255) or 585-263-9994, email, Facebook or Twitter. Connections is also livestreamed on the WXXI News YouTube channel each day. You can watch live or access previous episodes here.---Do you have a story that needs to be shared? Pitch your story to Connections.

(Feb 26, 2026) Champlain Area Trails recently acquired the Twin Valleys Outdoor Education Center in Essex County. The almost 700-acre property is now open to the public for recreation, and CATS has big plans for the space in the future. Also: A state trooper escaped serious injury when she was struck by an out-of-control car on a Franklin County highway.

Sherrod Blakely, Kwani Lunis and Gary Washburn discuss the newest member of the Boston Celtics, Nikola Vučević. CLNS Media is Powered by:

We've had a number of water main breaks across Detroit and the tri-county area due to the cold, but Tuesday morning the problem was inside a building in Detroit's New Center area where a water line broke and caused major flooding. WWJ's Chris Fillar and Jackie Paige have your Tuesday morning news. (Photo credit: WWJ's Charlie Langton)

In this episode, we move into what becomes available after fear has been met with presence.If you've stayed with the pause…If something true has ended…If fear has loosened its grip but action has not yet arrived…This episode is about the new foundation that begins to form beneath change.We explore:what stabilizes you when fear is no longer running the systemwhy wholeness is not a future achievement, but a present statehow rebuilding from urgency recreates old instabilitywhat shifts in leadership when you stop compensating for uncertaintythe role of inner connection as the bridge between life and leadershipwhy timing and rhythm matter more than effort in this phaseThis is not an episode about fixing, forcing, or figuring things out.It's an invitation to recognize the quiet center that forms when coherence replaces survival.When you're in a season of reorganization—where the old has ended and the new is still emerging—this episode offers orientation, steadiness, and permission to stay with what is already whole.—If this episode met you, you're welcome to join Sacred Notes — a quiet weekly rhythm I share by email → https://paulaimmo.myflodesk.com/sacrednotes —Keywords: leadership after fear, inner wholeness and leadership, navigating change without urgency, post-fear integration, leading from inner coherence

WACKER and SICO Performance Material opened a 2,300-square-meter application development center in Jining, China, to advance organofunctional silane technology for plastics, coatings, and adhesives. The facility consolidates research, technical support, and production resources, enabling faster product development and market introduction. WACKER holds a majority stake in SICO and aims to address rising demand for specialty silanes in sectors such as electromobility, electronics, power engineering, and telecommunications.Learn more on this news by visiting us at: https://greyjournal.net/news/ Hosted on Acast. See acast.com/privacy for more information.

The government manages a $5 trillion credit portfolio across more than 125 programs, and a new organization wants to bring technology, consistency, and integrity to that system. We'll explore the mission and vision of the Center for USA Lending with its founder, Doug Criscitello.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mike and Mike previewed the Saints' matchup with the Falcons, highlighting Atlanta's offensive line.

Join Gareth & Nadgy as they dissect the victory over the Falcons at Levi's Stadium.

The future of rail and buses to and from other cities and Detroit may be here. Detroit's new multi-modal transit hub plans to include Amtrak service, with an expanded Wolverine Line connecting to Windsor and Toronto; as well as consolidate both the Amtrak station in Detroit's New Center and the intercity bus terminal on Howard in Detroit. $40 million has been allocated for the project, and site evaluation and design work is beginning. Beth Kmetz from Michigan Central joins us for a segment of the Daily Detroit podcast, sharing all the details that are set so far from this important announcement from Gov. Gretchen Whitmer at the Downtown Detroit Partnership Fall Forum. You'll also learn why the new station is going next to the historic and redeveloped Michigan Central vs. right into the old hub. Daily Detroit shares what to know and where to go in Metro in Detroit every day, and has every day for more than 1700 episodes. You can follow us on Apple Podcasts: https://podcasts.apple.com/us/podcast/daily-detroit/id1220563942  And support our work on Patreon: https://www.patreon.com/DailyDetroit  Feedback as always - dailydetroit -at- gmail -dot- com or leave a voicemail 313-789-3211.

Mike Johnson spends some time talking about what's going on at Talladega Superspeedway this weekend with Talladega Superspeedway President Brian Crichton. Then, Mike Johnson, Dylan Mathews, and Ali Mac give out their first quarter grades to the Atlanta Falcons' offensive line.

Husband-and-wife team William Firth Wells and Mildred Weeks Wells conducted research that had the potential to make a big difference in the safety of indoor air. But it didn’t really have a significant impact on public health. Research: Associated Press. “Super-Oyster Is On its Way to Dinner Table Bigger and Better Bivalve Sports Pedigree.” 3/13/1927. https://www.loc.gov/resource/sn84020064/1927-03-13/ed-1/?sp=14 “Brought Back to Texas.” The Houston Semi-Weekly Post. 12/26/1889. https://www.newspapers.com/image/1196039760/ Decatur Daily Review. “Scientists Fight Flu Germs with Violet Ray.” 7/30/1936. https://www.newspapers.com/image/94335504/ Evening Star. “Scientific Trap-shooter.” 6/26/1937. https://www.loc.gov/resource/sn83045462/1937-06-26/ed-1/?sp=7&q=William+Firth+Wells&r=0.668,0.557,0.438,0.158,0 Fair, Gordon M. and William Weeks Wells. “Method and Apparatus for Preventing Infection.” U.S. Patent 2,198,867. https://ppubs.uspto.gov/api/pdf/downloadPdf/2198867 Hall, Dominic. “New Center for the History of Medicine Artifact - Wells Air Centrifuge.” Harvard Countway Library. https://countway.harvard.edu/news/new-center-history-medicine-artifact-wells-air-centrifuge “Incubator Is Now Oyster Nurse.” Washington Times. 10/1/1925. https://www.loc.gov/resource/sn84026749/1925-10-01/ed-1/?sp=12 Lewis, Carol Sutton. “Mildred Weeks Wells’s Work on Airborne Transmission Could Have Saved Many Lives—If the Scientific Establishment Listened.” Lost Women of Science Podcast. Scientific American. 5/22/2025. https://www.scientificamerican.com/article/a-public-health-researcher-and-her-engineer-husband-found-how-diseases-can/ Library and Archives Team. “William Firth Wells and Mildred Weeks Wells.” Washington College. https://www.washcoll.edu/people_departments/offices/miller-library/archives-special-collections/archives-blog/Wells%20papers.php Molenti, Megan. “The 60-Year-Old Scientific Screwup That Helped Covid Kill.” Wired. 5/13/2021. https://www.wired.com/story/the-teeny-tiny-scientific-screwup-that-helped-covid-kill/ Perkins JE, Bahlke AM, Silverman HF. Effect of Ultra-violet Irradiation of Classrooms on Spread of Measles in Large Rural Central Schools Preliminary Report. Am J Public Health Nations Health. 1947 May;37(5):529-37. PMID: 18016521; PMCID: PMC1623610. Randall, Katherine and Ewing, E. Thomas and Marr, Linsey and Jimenez, Jose and Bourouiba, Lydia, How Did We Get Here: What Are Droplets and Aerosols and How Far Do They Go? A Historical Perspective on the Transmission of Respiratory Infectious Diseases (April 15, 2021). Available at SSRN: https://ssrn.com/abstract=3829873 Riley, Richard L. “What Nobody Needs to Know About Airborne Infection.” American Journal of Respiratory and Critical Care Medicine. Volume 163, Issue 1. https://www.atsjournals.org/doi/10.1164/ajrccm.163.1.hh11-00 Simon, Clea. “Did a socially awkward scientist set back airborne disease control?” The Harvard Gazette. 3/7/2025. https://news.harvard.edu/gazette/story/2025/03/did-a-socially-awkward-scientist-set-back-airborne-disease-control/ “Texas State News.” McKinney Weekly Democrat-Gazette. 4/17/1890. https://www.newspapers.com/image/65385350/ WELLS MW, HOLLA WA. VENTILATION IN THE FLOW OF MEASLES AND CHICKENPOX THROUGH A COMMUNITY: Progress Report, Jan. 1, 1946 to June 15, 1949, Airborne Infection Study, Westchester County Department of Health. JAMA. 1950;142(17):1337–1344. doi:10.1001/jama.1950.02910350007004 WELLS MW. VENTILATION IN THE SPREAD OF CHICKENPOX AND MEASLES WITHIN SCHOOL ROOMS. JAMA. 1945;129(3):197–200. doi:10.1001/jama.1945.02860370019006 WELLS WF, WELLS MW. AIR-BORNE INFECTION. JAMA. 1936;107(21):1698–1703. doi:10.1001/jama.1936.02770470016004 WELLS WF, WELLS MW. AIR-BORNE INFECTION: SANITARY CONTROL. JAMA. 1936;107(22):1805–1809. doi:10.1001/jama.1936.02770480037010 Wells, W F, and M W Wells. “Measurement of Sanitary Ventilation.” American journal of public health and the nation's health vol. 28,3 (1938): 343-50. doi:10.2105/ajph.28.3.343 Wells, William Firth and Gordon Maskew Fair. Viability of B. coli Exposed to Ultra-Violet Radiation in Air.Science82,280-281(1935).DOI:10.1126/science.82.2125.280.b Wells, William Firth and Mildred Weeks Wells. Measurement of Sanitary Ventilation American Journal of Public Health and the Nations Health 28, 343_350, https://doi.org/10.2105/AJPH.28.3.343 Zimmer, Carl. “Air-Borne: The Hidden History of the Life We Breathe.” Dutton. 2025. See omnystudio.com/listener for privacy information.

The Blue Jackets have a new center ice logo, Talking about what we like about Dean Evanson and so  much more!

Detroit police are investigating a deadly shooting that left one dead and one injured. The victims' SUV ended up in front of Henry Ford Hospital. WWJ's Jackie Paige has your Friday morning news.

Fabrizio Romano breaks down all the latest on Chelsea ahead of the last two weeks of the summer transfer window. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week on The Conscious Consultant Hour, Sam is joined by Ralph White, a pioneer in holistic education and a guiding light in the esoteric and consciousness movements.Ralph was the visionary co-founder of the New York Open Center, which served for nearly four decades as the city's primary hub for holistic learning, spiritual exploration, and transformative education. Now, as Director and President of the New Center for Holistic Learning, Ralph continues this rich legacy, ushering in a new chapter for seekers, healers, and wisdom keepers alike.In this enlightening conversation, Ralph shares stories from his remarkable journey, curating global conferences through the Esoteric Quest series, supporting the evolution of end-of-life consciousness with the Art of Dying work, and holding space for the reawakening of ancient wisdom in modern times. His path weaves together deep spirituality, cultural history, and an unwavering dedication to the inner life.Whether you're drawn to the mysteries of the soul, curious about esoteric traditions, or simply seeking deeper meaning in an ever-changing world, this episode will nourish your mind and heart. Join us as we explore how the sacred, the mystical, and the practical can come together to foster individual awakening and collective transformation.Tune in and share all of your questions and comments about Esoteric Traditions on our YouTube livestream or on our Facebook page.https://www.newcenterny.org/Support this podcast at — https://redcircle.com/the-conscious-consultant-hour8505/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Hour 1: Why Texans' new center will be so important for offensive line full 2255 Thu, 17 Jul 2025 23:36:44 +0000 UjLJEJ7fOQhRQAsl3PuKJOyiktsyyi8c nfl,mlb,nba,texans,astros,rockets,sports The Drive with Stoerner and Hughley nfl,mlb,nba,texans,astros,rockets,sports Hour 1: Why Texans' new center will be so important for offensive line 2-6PM M-F © 2025 Audacy, Inc. Sports False https://player.amperwa

Eric Topol (00:05):Hello, it's Eric Topol from Ground Truths, and I've got some really exciting stuff to talk to you about today. And it's about the announcement for a new Center for pediatric CRISPR Cures. And I'm delight to introduce doctors Jennifer Doudna and Priscilla Chan. And so, first let me say this is amazing to see this thing going forward. It's an outgrowth of a New England Journal paper and monumental report on CRISPR in May. [See the below post for more context]Let me introduce first, Dr. Doudna. Jennifer is the Li Ka Shing Chancellor's Chair and a Professor in the departments of chemistry and of molecular and cell biology at the University of California Berkeley. She's also the subject of this book, one of my favorite books of all time, the Code Breaker. And as you know, the 2020 Nobel Prize laureate for her work in CRISPR-Cas9 genome editing, and she founded the Innovative Genomics Institute (IGI) back 10 years ago. So Jennifer, welcome.Jennifer Doudna (01:08):Thank you, Eric. Great to be here.Eric Topol (01:10):And now Dr. Priscilla Chan, who is the co-founder of the Chan Zuckerberg Initiative (CZI) that also was started back in 2015. So here we are, a decade later, these two leaders. She is a pediatrician having trained at UCSF and is committed to the initiative which has as its mission statement, “to make it possible to cure, prevent, and manage all diseases in this century.” So today we're going to talk about a step closer to that. Welcome, Priscilla.Priscilla Chan (01:44):Thank you. Thanks for having me.Eric Topol (01:46):Alright, so I thought we'd start off by, how did you two get together? Have you known each other for over this past decade since you both got all your things going?Jennifer Doudna (01:56):Yes, we have. We've known each other for a while. And of course, I've admired the progress at the CZI on fundamental science. I was an advisor very early on and I think actually that's how we got to know each other. Right, Priscilla?Priscilla Chan (02:11):Yeah, that's right. We got to know each other then. And we've been crisscrossing paths. And I personally remember the day you won the Nobel Prize. It was in the heart of the pandemic and a lot of celebrations were happening over Zoom. And I grabbed my then 5-year-old and got onto the UCSF celebration and I was like, look, this is happening. And it was really cool for me and for my daughter.Eric Topol (02:46):Well, it's pretty remarkable convergence leading up to today's announcement, but I know Priscilla, that you've been active in this rare disease space, you've had at CZI a Rare As One Project. Maybe you could tell us a bit about that.Priscilla Chan (03:01):Yeah, so at CZI, we work on basic science research, and I think that often surprises people because they know that I'm a pediatrician. And so, they often think, oh, you must work in healthcare or healthcare delivery. And we've actually chosen very intentionally to work in basic science research. In part because my training as a pediatrician at UCSF. As you both know, UCSF is a tertiary coronary care center where we see very unusual and rare cases of pediatric presentations. And it was there where I learned how little we knew about rare diseases and diseases in general and how powerful patients were. And that research was the pipeline for hope and for new discoveries for these families that often otherwise don't have very much access to treatments or cures. They have a PDF that maybe describes what their child has. And so, I decided to invest in basic science through CZI, but always saw the power of bringing rare disease patient cohorts. One, because if you've ever met a parent of a child with rare disease, they are a force to be reckoned with. Two, they can make research so much better due to their insights as patients and patient advocates. And I think they close the distance between basic science and impact in patients. And so, we've been working on that since 2019 and has been a passion of ours.Eric Topol (04:40):Wow, that's great. Now Jennifer, this IGI that you founded a decade ago, it's doing all kinds of things that are even well beyond rare diseases. We recently spoke, I know on Ground Truths about things as diverse as editing the gut microbiome in asthma and potentially someday Alzheimer's. But here you were very much involved at IGI with the baby KJ Muldoon. Maybe you could take us through this because this is such an extraordinary advance in the whole CRISPR Cures story.Jennifer Doudna (05:18):Yes, Eric. It's a very exciting story and we're very, very proud of the teamwork that went into making it possible to cure baby KJ of his very rare disease. And in brief, the story began back in August of last year when he was born with a metabolic disorder that prevented him from digesting protein, it's called a urea cycle disorder and rare, but extremely severe. And to the point where he was in the ICU and facing a very, very difficult prognosis. And so, fortunately his clinical team at Children's Hospital of Philadelphia (CHOP) reached out to Fyodor Urnov, who is the Director of Translational Medicine at the IGI here in the Bay Area. They teamed up and realized that they could quickly diagnose that child because we had an IRB approved here at the IGI that allowed us to collect patient samples and do diagnosis. So that was done.Jennifer Doudna (06:26):We created an off-the-shelf CRISPR therapy that would be targeted to the exact mutation that caused that young boy's disease. And then we worked with the FDA in Washington to make sure that we could very safely proceed with testing of that therapy initially in the lab and then ultimately in two different animal models. And then we opened a clinical trial that allowed that boy to be enrolled with, of course his parents' approval and for him to be dosed and the result was spectacular. And in fact, he was released from the hospital recently as a happy, healthy child, gaining lots of weight and looking very chunky. So it's really exciting.Eric Topol (07:16):It's so amazing. I don't think people necessarily grasp this. This timeline [see above] that we'll post with this is just mind boggling how you could, as you said Jennifer, in about six months to go from the birth and sequencing through cell specific cultures with the genome mutations through multiple experimental models with non-human primates even, looking at off-target effects, through the multiple FDA reviews and then dosing, cumulatively three dosing to save this baby's life. It really just amazing. Now that is a template. And before we go to this new Center, I just wanted to also mention not just the timeline of compression, which is unimaginable and the partnership that you've had at IGI with I guess Danaher to help manufacture, which is just another part of the story. But also the fact that you're not just even with CRISPR 1.0 as being used in approvals previously for sickle cell and β-thalassemia, but now we're talking about base editing in vivo in the body using mRNA delivery. So maybe you could comment on that, Jennifer.Jennifer Doudna (08:38):Yeah, very good point. So yeah, we used a version of CRISPR that was created by David Liu at the Broad Institute and published and available. And so, it was possible to create that, again, targeted to the exact mutation that caused baby KJ's disease. And fortunately, there was also an off-the-shelf way to deliver it because we had access to lipid nanoparticles that were developed for other purposes including vaccinations. And the type of disease that KJ suffered from is one that is treatable by editing cells in the liver, which is where the lipid nanoparticle naturally goes. So there were definitely some serendipity here, but it was amazing how all of these pieces were available. We just had to pull them together to create this therapy.Eric Topol (09:30):Yeah, no, it is amazing. So that I think is a great substrate for starting a new Center. And so, maybe back to you Priscilla, as to what your vision was when working with Jennifer and IGI to go through with this.Priscilla Chan (09:45):I think the thing that's incredibly exciting, you mentioned that at CZI our mission is to cure, prevent, and manage all disease. And when we talked about this 10 years ago, it felt like this far off idea, but every day it seems closer and closer. And I think the part that's super exciting about this is the direct connection between the basic science that's happening in CRISPR and the molecular and down to the nucleotide understanding of these mutations and the ability to correct them. And I think many of us, our imaginations have included this possibility, but it's very exciting that it has happened with baby KJ and CHOP. And we need to be able to do the work to understand how we can treat more patients this way, how to understand the obstacles, unblock them, streamline the process, bring down the cost, so that we better understand this pathway for treatment, as well as to increasingly democratize access to this type of platform. And so, our hope is to be able to do that. Take the work and inspiration that IGI and the team at CHOP have done and continue to push forward and to look at more cases, look at more organ systems. We're going to be looking in addition to the liver, at the bone marrow and the immune system.Priscilla Chan (11:17):And to be able to really work through more of the steps so that we can bring this to more families and patients.Eric Topol (11:30):Yeah, well it's pretty remarkable because here you have incurable ultra-rare diseases. If you can help these babies, just think of what this could do in a much broader context. I mean there a lot of common diseases have their roots with some of these very rare ones. So how do you see going forward, Jennifer, as to where you UC Berkeley, Gladstone, UCSF. I'm envious of you all up there in Northern California I have to say, will pull this off. How will you get the first similar case to KJ Muldoon going forward?Jennifer Doudna (12:13):Right. Well, IGI is a joint institute, as you probably know, Eric. So we were founded 10 years ago as a joint institute between UC Berkeley and UCSF. And now we have a third campus partner, UC Davis and we have the Gladstone Institute. So we've got an extraordinary group of clinicians and researchers that are coming together for this project and the Center to make it a success. We are building a clinical team at UCSF. We have several extraordinary leaders including Jennifer Puck and Chris Dvorak, and they are both going to be involved in identifying patients that could be enrolled in this program based on their diagnosis. And we will have a clinical advisory group that will help with that as well. So we'll be vetting patients probably right after we announce this, we're going to be looking to start enrolling people who might need this type of help.Eric Topol (13:18):Do you think it's possible to go any faster right now than the six months that it took for KJ?Jennifer Doudna (13:26):I think it could be. And here's the reason. There's a very interesting possibility that because of the type of technology that we're talking about with CRISPR, which fundamentally, and you and I have talked about this previously on your other podcast. But we've talked about the fact that it's a programmable technology and that means that we can change one aspect of it, one piece of it, which is a piece of a molecule called RNA that's able to direct CRISPR to the right sequence where we want to do editing and not change anything else about it. The protein, the CRISPR protein stays the same, the delivery vehicle stays the same, everything else stays the same. And so, we're working right now with FDA to get a platform designation for CRISPR that might allow streamlining of the testing process in some cases. So it'll obviously come down to the details of the disease, but we're hopeful that in the end it will be possible. And Priscilla and I have talked about this too, that as AI continues to advance and we get more and more information about rare diseases, we'll be able to predict accurately the effects of editing. And so, in some cases in the future it may be possible to streamline the testing process even further safely.Eric Topol (14:51):And I also would note, as you both know, well this administration is really keen on genome editing and they've had a joint announcement regarding their support. And in my discussions with the FDA commissioner, this is something they are very excited about. So the timing of the new Center for pediatric CRISPR Cures is aligned with the current administration, which is good to see. It's not always the case. Now going back, Priscilla, to your point that not just for the liver because delivery has been an issue of course, and we're going to try to get after a lot of these really rare diseases, it's going to go beyond there. So this is also an exciting new dimension of the Center, as you said, to go after the bone marrow for hematopoietic cells, perhaps other organs as well.Priscilla Chan (15:42):I mean what the expertise and feasibility, the immune system is going to be the next target. Jennifer Puck has been a pioneer in this work. She's the one who designed the newborn screen that will be the tool that picks up these patients as they are born. And I think the thing that's tremendous is the immune system, first of all is active in many, many diseases, not just these cases of children born with partial or absence of immune systems. And the course right now that these babies are left with is complete isolation and then a very long and arduous course of a bone marrow transplant with high morbidity and mortality. And even if after the transplant you have complications like graft versus host and immunosuppression. And so, the idea of being able to very specifically and with less the conditioning and morbidity and mortality of the treatment, being able to address this is incredible. And the implications for other diseases like blood cancers or other hematopoietic diseases, that's incredible. And that actually has an incredibly broad base of patients that can benefit from the learnings from these babies with severe combined immunodeficiencies.Eric Topol (17:10):Yeah, I think that goes back to a point earlier maybe to amplify in that previous CRISPR generation, it required outside the body work and it was extremely laborious and time consuming and obviously added much more to the expense because of hospitalization time. This is different. This is basically doing this inside the affected patient's body. And that is one of the biggest reasons why this is a big step forward and why we're so fortunate that your Center is moving forward. Maybe before we wrap up, you might want to comment, Jennifer on how you were able to bring in to build this platform, the manufacturing arm of it, because that seems to be yet another dimension that's helpful.Jennifer Doudna (18:01):Indeed, yes. And we were again fortunate with timing because you mentioned briefly that the IGI had set up a program with the Danaher Corporation back in January of last year. We call it our Beacon project. And it's focused on rare disease. And it's a really interesting kind of a unique partnership because Danaher is a manufacturing conglomerate. So they have companies that make molecules, they make proteins, they make RNA molecules, they make delivery molecules. And so, they were excited to be involved with us because they want to be a provider of these types of therapies in the future. And they can see the future of CRISPR is very exciting. It's expanding, growing area. And so, that agreement was in place already when the baby KJ case came to our attention. And so, what we're hoping to do with Danaher is again, work with them and their scientists to continue to ask, how can we reduce the cost of these therapies by reducing the cost of the molecules that are necessary, how to make them efficiently. We already, it's very interesting, Fyodor Urnov has toured their plant in North Dakota recently, and he found in talking to their engineers, there are a number of things that we can already see will be possible to do that are going to make the process of manufacturing these molecules faster and cheaper by a lot.Eric Topol (19:28):Wow.Jennifer Doudna (19:28):So it's a win-win for everybody. And so, we're really excited to do that in the context of this new Center.Eric Topol (19:36):Oh, that's phenomenal because some of these disorders you don't have that much time to work with before they could be brain or organ or vital tissue damage. So that's great to hear that. What you built here is the significance of it can't be under emphasized, I'll say because we have this May report of baby KJ, which could have been a one-off and it could have been years before we saw another cure of an ultra-rare disorder. And what you're doing here is insurance against that. You're going to have many more cracks at this. And I think this is the excitement about having a new dedicated Center. So just in closing, maybe some remarks from you Priscilla.Priscilla Chan (20:24):I just want to emphasize one point that's really exciting as we talk about these ultra-rare cases that they're often like one in a million. All these learnings actually help maximize the impact of lots of research across the sector that impacts actually everyone's health. And so, our learnings here from these patients that have very significant presentations that really can stand to benefit from any treatment is hopefully paving the way for many, many more of us to be able to live healthier, higher quality lives through basic science.Eric Topol (21:13):And over to you, Jennifer.Jennifer Doudna (21:15):Couldn't agree more. It's a really interesting moment. I think what we hope we are, is we're at sort of an inflection point where, as I mentioned earlier, all the pieces are in place to do this kind of therapeutic and we just need a team that will focus on doing it and pulling it together. And also learning from that process so that as Priscilla just said, we are ultimately able to use the same strategy for other diseases and potentially for diseases that affect lots of people. So it's exciting.Eric Topol (21:46):For sure. Now, if I could just sum up, this is now a decade past the origination of your work of CRISPR and how already at the first decade culminated in sickle cell disease treatment and β-thalassemia. Now we're into the second decade of CRISPR. And look what we've seen, something that was unimaginable until it actually happened and was reported just a little over a month ago. Now going back to Priscilla's point, we're talking about thousands of different rare Mendelian genomic disorders, thousands of them. And if you add them all up of rare diseases, we're talking about hundreds of millions of people affected around the world. So this is a foray into something much bigger, no less the fact that some of these rare mutations are shared by common diseases and approaches. So this really big stuff, congratulations to both of you and your organizations, the Innovative Genomics Institute and the Chan Zuckerberg Initiative for taking this on. We'll be following it with very deep interest, thank you.****************************************************Thanks for listening, reading and subscribing to Ground Truths.If you found this interesting PLEASE share it!That makes the work involved in putting these together especially worthwhile.Thanks to Scripps Research, and my producer, Jessica Nguyen, and Sinjun Balabanoff for video/audio support.All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe

Anthony and Raj discuss the Brook Lopez noise after Anthony tells the story about how he found out Lopez was not exactly in a hurry to stick around long-term with the Lakers. From there, they discuss the approach they'd prefer the Lakers take at that position. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

The new Center for Global Pediatric Health, an initiative between the Robert J. Havey, MD Institute for Global Health and Ann & Robert H. Lurie Children's Hospital of Chicago, is building a global community committed to improving the health of children worldwide. In this episode, Drs. Colleen Fant and Sahera Dirajlal-Fargo, co-directors of the new center, discuss their goals for the center, their own journeys in global pediatric health as well as emerging trends and challenges in pediatric care worldwide.

On this episode, Kyle Jordan and Steve Kane join the podcast to discuss some updates on SpaceTEC® Partners‘ new Florida training facility and its role in preparing the next generation of composite technicians. Kyle is the director of certifications for the ACMA, and Steve is the executive director of SpaceTEC® Partners.  SpaceTEC® Partners offers Aerospace, Aviation, […] The post Building Tomorrow's Workforce: SpaceTEC's New Center and the Role of CCT Certification first appeared on Composites Weekly. The post Building Tomorrow's Workforce: SpaceTEC's New Center and the Role of CCT Certification appeared first on Composites Weekly.

Kevin Curtis, clinical operations director at the Mental Health Crisis Care Center, and Dr. Mike Franz, executive medical director for behavioral health at Regence, talk about the new crisis care center in Utah and what it can teach us about how to best address the national mental health epidemic. 

Plus: Virginia's former state health commissioner is now warning that the U.S. Health and Human Services Department's recent decision to cut federal funding for COVID-related grants makes Virginians more susceptible to future pandemics — and “horrific consequences.”    In the podcast: Virginia is the top state to survive an alien invasion; Sens. Kaine and Warner's candidates for the U.S. Attorney for the Western District of Virginia 

(00:00) Joe Burrow's comments were a “big help” in getting contracts done(9:00) Tee Higgins prefers not to be known as the highest-paid No. 2 receiver(13:00) Vikings have rejected trade calls on J.J. McCarthy, not pursuing Aaron Rodgers at the moment(17:20) Eagles DE Brandon Graham officially retires after 15 seasons(27:30) PFT Live Draft: Under the Radar Super Bowl Heroes(38:30) Cowboys were interested in Cooper Kupp until they heard the numbers(45:35) What's the hold up between Cowboys & Micah Parsons?(53:30) Patriots reach 2-year deal with center Garrett Bradbury 

We're on with Morgane Billuart, a writer and artist and a researcher whose work engages critically with technologically mediated and determined worlds — not least within her exceptional book “Cycles, the Sacred and the Doomed: Inquiries in Female Health Technologies.” Morgane joins us to talk about a large, recent research project on a particular character that many of us identifies with, what Geert Lovink calls the “critical internet researcher” — a figure who engages in a kind of postdisciplinary media theory while at the same time producing and publishing their work through the very media they are studying, the Online. We strongly recommend:Morgane's podcasts Becoming the Product and Girl Employee with Carmen HinesMorgane's substack Becoming the ProductMorgane's book Cycles, the Sacred and the Doomed: Inquiries in Female Health Technologies on Set MarginsIn the episode we discuss the work of Geert Lovink and the Institute of Network Cultures and Joshua Citarella (and the associated entity Do Not Research), and we briefly touch on Yancy Strickler (and the associated MetaLabel), Trust, the New Center for Research and Practice, Are.na, New Models, and RADAR (https://www.radardao.xyz/). All are mentioned in the context of being institutions undertaking the extremely admirable charge of iterating upon new vehicles and structures for the exchange of information. Marek also briefly mentions the blogger RM (@NilsEdison) and the artist Maria Tsylke.

Get ready for an inspiring and deeply personal conversation with Karla Redding-Andrews and Justin Andrews, the heart and soul behind the Otis Redding Foundation and the guardians of Otis Redding's timeless musical legacy. We explore the profound impact of Otis Redding's music, from his iconic hits to his enduring influence on generations of artists. Discover the vital work of the Otis Redding Foundation in nurturing young talent through arts and music programs, and celebrate the grand opening of the state-of-the-art Otis Redding Center for the Arts. Plus, we'll be sharing incredible stories passed down by the legendary Zelma Redding, widow of Otis Redding and President & Founder of the Otis Redding Foundation, offering unique insights into his life and legacy. We'll also delve into the complexities of managing a legendary estate, including the fascinating process of clearing iconic songs for use in modern productions, like the unforgettable "Otis (feat. Otis Redding)" collaboration between JAY-Z and Kanye West. And finally, get an exciting glimpse into the upcoming biopic starring Jon Boyega, centered around Zelma Redding's remarkable story, and how it will bring Otis Redding's legacy to a new generation. This episode is a must-listen for music lovers and anyone passionate about preserving and celebrating artistic legacies. Learn more about your ad choices. Visit megaphone.fm/adchoices

Logan, Raja, and Howard start their trade deadline recap by discussing the Jimmy Butler trade and whether this was the right move for the Warriors (1:55). Then they discuss the Lakers getting Mark Williams from Charlotte (32:27) and De'Aaron Fox's first game as a Spur (37:30). Then they pick out some winners and losers (45:32) and wrap up with their Real Ones of the Week (1:05:45). Hit the mailbag! realonesmailbag@gmail.com Get your tickets to the live show at Punch Line San Francisco on February 15 here. The Ringer is committed to responsible gaming. Please visit www.rg-help.com to learn more about the resources and helplines available. Hosts: Logan Murdock, Raja Bell, and Howard Beck Producer: Isaiah Blakely Additional Production Supervision: Ben Cruz Learn more about your ad choices. Visit podcastchoices.com/adchoices

On today's all-local podcast: An update on the proposal to cover  I-75 in downtown Detroit with parks, including funding and what's next New Center's potential sparks optimisim with a listener Another listener says that the Mayor's Race Open, but asks if anyone will match Mike Duggan's Influence? And a third listeners asks Devon about Dearborn's development potential, and he shares his predictions  Daily Detroit shares what to know and where to go in Detroit every day. You can listen to their podcast and read their newsletter. Find us on Apple Podcasts: https://podcasts.apple.com/us/podcast/daily-detroit/id1220563942 Or sign up for our newsletter: https://www.dailydetroit.com/newsletter/  

The New Center of Power of the World full 679 Wed, 08 Jan 2025 14:18:58 +0000 2z4pLG4Q2LcmD8GrEoQoOX4Bmb6O7rZF news The Tara Show news The New Center of Power of the World Tara presides over the Upstate's #1 all news/talk morning show every weekday on News/Talk 989 WORD.Tara's faithful listeners are affectionately known as "Tara-ists" because of their passion and participation in the show. Tara was named 2021 Best News Talk Show and Best overall Personality, AGAIN, by the South Carolina Broadcasters Association! Tara took home the same honors in 2018 and was also named 2016 "Personality of the Year!" In addition, Tara has also won over two dozen state and national journalism awards for column writing, news reporting and investigative reporting while working for three newspapers and writing for a variety of national publications. She won a first place reporting award from the North Carolina Press Association for an investigative series about the weaknesses in Charlotte's overburdened court system, which regularly let murderers off the hook with less than 15 years in prison. Due to her work, that system has been reformed. Tara is also a winner of the prestigious first place Green Eyeshade Award, a national award for column writing from The Society of Professional Journalists. Tara took to the airwaves about 15 years ago to do a radio show heard up and down the coast and fell in love with bypassing her editors to talk straight to the people. Tara hasn't stopped reporting, and still brings her investigative journalism to the show. Tara is a mom, wife and talk radio convert-- and weekday mornings she's live and local on News/Talk 989 WORD. Are you a "Tara-ist"? It's time to get captured!      2024 © 2021 Audacy, Inc. News False https://player.amperwavepodcasting.com?feed-link=https%3A%2F%2Frss.amperwave.net%2Fv2

Hour 1: The Tara Show - “The New Center of Power of the World" Trump is Legend” “Yesterday's Epic Press Release” “Trump's Ultimate Troll Strategy” full 2019 Wed, 08 Jan 2025 16:21:34 +0000 jB4Bm0BEfNIH7MfYjEgTkChuRAWTHdN4 news The Tara Show news Hour 1: The Tara Show - “The New Center of Power of the World" Trump is Legend” “Yesterday's Epic Press Release” “Trump's Ultimate Troll Strategy” Tara presides over the Upstate's #1 all news/talk morning show every weekday on News/Talk 989 WORD.Tara's faithful listeners are affectionately known as "Tara-ists" because of their passion and participation in the show. Tara was named 2021 Best News Talk Show and Best overall Personality, AGAIN, by the South Carolina Broadcasters Association! Tara took home the same honors in 2018 and was also named 2016 "Personality of the Year!" In addition, Tara has also won over two dozen state and national journalism awards for column writing, news reporting and investigative reporting while working for three newspapers and writing for a variety of national publications. She won a first place reporting award from the North Carolina Press Association for an investigative series about the weaknesses in Charlotte's overburdened court system, which regularly let murderers off the hook with less than 15 years in prison. Due to her work, that system has been reformed. Tara is also a winner of the prestigious first place Green Eyeshade Award, a national award for column writing from The Society of Professional Journalists. Tara took to the airwaves about 15 years ago to do a radio show heard up and down the coast and fell in love with bypassing her editors to talk straight to the people. Tara hasn't stopped reporting, and still brings her investigative journalism to the show. Tara is a mom, wife and talk radio convert-- and weekday mornings she's live and local on News/Talk 989 WORD. Are you a "Tara-ist"? It's time to get captured!      2024 © 2021 Audacy, Inc. News False https://player.amperwavepodcasting.com?feed-link=https%3A%2F%2

This week, we are happy welcome Child and Adolescent Psychiatrist and psychoanalyst, Dr. Deborah Lynn to The Hamilton Review Podcast! Dr. Lynn shares with the audience how to help your child overcome anxiety and more. Dr. Lynn is a expert in her field - parents, this is a must listen conversation. Dr. Deborah Lynn is a Board-Certified psychiatrist, a Child and Adolescent Psychiatrist and psychoanalyst. She is on the clinical faculty of the University of California, Los Angeles, teaching at UCLA for over 20 years. Her early career was spent investigating the biology of mother-infant separation, ADHD, temperament, and an in depth investigation of personality development. Dr. Lynn has been in private practice in Westwood, California for over 20 years. She teaches at UCLA and the New Center for Psychoanalysis. She also works as a consultant for City of Hope, addressing psychiatric issues in a consultation/liaison modality in the pediatric oncology population. Dr. Lynn is a graduate of Northwestern Medical School, University of Chicago, and University of Wisconsin, Madison for Psychiatric Residency, and UCLA Child and Adolescent for Child and Adolescent Fellowship and Research Fellowship. She is a long time member, instructor, and senior candidate at the New Center for Psychoanalysis, Los Angeles. She is a faculty member of Reiss-Davis Child Study Center. How to contact Dr. Deborah Lynn:   Center for Authenticity   How to contact Dr. Bob: Dr. Bob on YouTube: https://www.youtube.com/channel/UChztMVtPCLJkiXvv7H5tpDQ Dr. Bob on Instagram: https://www.instagram.com/drroberthamilton/ Dr. Bob on Facebook: https://www.facebook.com/bob.hamilton.1656 Dr. Bob's Seven Secrets Of The Newborn website: https://7secretsofthenewborn.com/ Dr. Bob's website: https://roberthamiltonmd.com/ Pacific Ocean Pediatrics: http://www.pacificoceanpediatrics.com/  

This week's guest is UTSA's Dr. Bryan Gervais. He is an associate professor in the Department of Political Science & Geography, and he's in the studio because he is the inaugural director of the UTSA Center for Public Opinion Research (CPOR), the new poll launched in advance of the national elections. His areas of specialization are political communication and political psychology. Listen as Dr. Gervais discusses how accurate their polling proved in the recent national election, and what CPOR is learning about our local electorate.     

In the second hour of "Connections with Evan Dawson" on Oct. 17, 2024, we speak with Teen Empowerment youth and staff about their new space and their work helping young people in the community.