Podcasts about new drugs

In this conversation, Parker discusses his journey with Fight the New Drug, an organization dedicated to raising awareness about the harmful effects of pornography. He shares insights on the changing public perception of pornography, the importance of education and awareness, and the societal impacts of porn consumption. The discussion also touches on the ethics of pornography, the challenges of sexting among youth, and the crucial role parents play in guiding their children through these issues. This conversation delves into the multifaceted impacts of pornography on individuals and society, emphasizing the importance of home education, mental health, and the role of live events in raising awareness. The speaker discuss the escalating nature of pornography consumption, its detrimental effects on mental health, and the significance of research in informing the public. They also highlight the need for diverse influencer engagement and faith-based approaches to effectively communicate the message. Personal stories of recovery and the importance of self-care in addressing heavy topics are also explored. Got a Question? It Could Be on the Podcast! Submit It Through This Form Find Out More About My DeepClean Recovery Program Here Get A Free Copy of The Last Relapse, A Blueprint For Recovery Watch Sathiya on Youtube For More Content Like This   Chapters: 00:00 Introduction to Fight the New Drug 03:02 Parker's Journey with Fight the New Drug 05:57 Public Perception of Pornography 09:00 Educational Approaches to Pornography Awareness 11:54 Societal Impacts of Pornography 14:56 The Ethics of Pornography 18:12 Sexting and Its Consequences 20:57 Parental Guidance on Pornography and Sexting 28:32 The Role of Home Education in Addressing Pornography 29:00 Understanding the Individual Impact of Pornography 30:18 Mental Health and Pornography Consumption 33:04 Future Strategies for Raising Awareness 36:24 The Importance of Live Events in Education 37:08 The Role of Research in Awareness 38:44 Pandemic Effects on Pornography Consumption 40:28 Influencers and Celebrity Voices on Pornography 42:41 Diverse Influencer Engagement Strategies 44:20 Faith-Based Approaches to Pornography Education 47:10 Self-Care in Heavy Conversations 51:11 Powerful Stories of Recovery and Awareness

In PBSE Episode 280, Mark & Steve address the complex challenge faced by betrayed partners—especially those healing from porn or sex addiction in their relationships—who want to guide their teenage children toward healthy sexuality. It begins by acknowledging the emotional burden and conflict many betrayed partners feel, especially when trying to teach their children something they themselves are still struggling to reclaim. Drawing from a listener's heartfelt question, the hosts emphasize that children are already receiving sexual messaging from the world around them, making it crucial that parents step up to provide a healthy, grounded counter-narrative rooted in respect, consent, and emotional connection.The article challenges the outdated concept of “the talk” by promoting a new paradigm: sexuality should be an ongoing, evolving, and age-appropriate conversation that unfolds over years, not moments. Parents are encouraged to reflect on their own stories, recognize internal shame or awkwardness, and ensure that their emotional energy during these talks doesn't unintentionally pass discomfort or judgment onto their children. The authors stress that kids are emotional sponges, and how parents talk about sex—more than just what they say—deeply influences how their children feel about their own bodies, desires, and relationships. This is why intentionality and preparation matter more than perfection.Practical tools and resources are also discussed, such as those from Fight the New Drug, Defend Young Minds, and Covenant Eyes. The article affirms that even when a co-parent is absent or unsafe to engage in these conversations, there are still ways to ensure kids have positive, trustworthy influences. By speaking truthfully, embracing healthy sexual values, and modeling openness, betrayed partners can break generational cycles of secrecy, shame, and dysfunction. Each conversation—no matter how imperfect—is a step toward a legacy of empowerment, honesty, and loving connection.For a full transcript of this podcast in article format, go to:  As a Betrayed Partner, How do I Talk to my Teenage Kids About Healthy Sexuality?Learn more about Mark and Steve's revolutionary online porn/sexual addiction recovery and betrayal trauma healing program at—daretoconnectnow.comFind out more about Steve Moore at:  Ascension CounselingLearn more about Mark Kastleman at:  Reclaim Counseling Services

Ready to transform your life after discovering his betrayal (cheating, p*rn use, etc.)? Book a 1-on-1 Support Call: click here Self-paced, online course "Betrayal Survival Guide": Click here Apply for my 3-month coaching package: Click here P*rn addiction recovery resource: Click here Click below for more resources: TikTok Instagram Join my Women's Support Group "WTF Do I Do Now?" Website **Please subscribe and rate the show so the algorithm can help more girls find this resource and know they aren't alone in their healing journey from his cheating, p*rn use, etc.!

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Show Notes Episode 492: You STILL Want A New Drug Part 2 of the Crack Epidemic This week Host Dave Bledsoe thought he was done drinking but discovered his credit card company had (Foolishly) upped his credit limit. (This will not end well for either of them) On the show this week we deliver part two of the crack epidemic talking about all the lies told by white people to scare themselves about black people doing crack.  Along the way we find out that Dave is a little snitch.  Then we dive right into a totally unnecessary lesson on the historical geography of Washington DC. (Flimsiest pretext yet for a tangent.) Then we learn how the President of the United States entrapped a high school student to sell him crack. (Every word of that is true and mostly accurate.) From there we discover how Ronald Reagan (HE'S BACK!) set the stage for the mass incarceration of two generations of Black Men. (We're sure it was an accident.) Finally, we explain the most heinous lie of the whole damn lot of them, about moms, babies and medicine. Our Sponsor this week is Creative Problem Solving, fixing it by making it worse.  We open the show with Poppy Bush sharing his stash and close with Carson McKee who wonders if it will EVER be over? Show Theme: Hypnostate Prelude to Common Sense The Show on Bluesky: https://bsky.app/profile/whatthehellpodcast.bsky.social The Show on Facebook: https://www.facebook.com/whatthehellpodcast/ The Show on Youtube:  https://www.youtube.com/channel/UCjxP5ywpZ-O7qu_MFkLXQUQ The Show on Instagram: https://www.instagram.com/whatthehellwereyouthinkingpod/ Our Discord Server: https://discord.gg/kHmmrjptrq Our Website: www.whatthehellpodcast.com Patreon:  https://www.patreon.com/Whatthehellpodcast The Show Line: 347 687 9601 Closing Music: https://youtu.be/eofltXeiSVM?si=2IRyTVkIuYb2uI6m Buy Our Stuff: https://www.seltzerkings.com/shop Citations Needed: The Inside Story Of The Lafayette Park Crack Bust That George H.W. Bush Used To Sell The War On Drugs https://dcist.com/story/18/12/04/the-inside-story-of-the-lafayette-park-drug-bust-that-george-h-w-bush-used-to-sell-the-war-on-drugs/ The Disparate Treatment of Crack Cocaine and the Opioid Epidemic: Unveiling Racial Bias in Drug Policy https://www.scu.edu/government-ethics/resources/the-disparate-treatment-of-crack-cocaine-and-the-opioid-epidemic/#:~:text=Shortly%20thereafter%2C%20policymakers%20enacted%20the,impact%20on%20the%20Black%20community. Cracking Cocaine Myths https://pepperdine-graphic.com/cracking-cocaine-myths/ Demographic and socioeconomic correlates of powder cocaine and crack use among high school seniors in the United States https://pmc.ncbi.nlm.nih.gov/articles/PMC5066573/ Governmental efforts to address the epidemic https://www.britannica.com/topic/crack-epidemic#ref334577 Just Blowing Smoke? https://magazine.emory.edu/issues/2013/autumn/of-note/just-blowing-smoke/index.html Revisiting the ‘Crack Babies' Epidemic That Was Not https://www.nytimes.com/2013/05/20/booming/revisiting-the-crack-babies-epidemic-that-was-not.html Learn more about your ad choices. Visit podcastchoices.com/adchoices

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: A new Austrailian study aims to prevent type 1, the new twiist pump will integrate with Eversnse CGM as well as Libre, diabetes deaths are down in the US, Dexcom U is looking for college athletes, and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX A world-first human trial of a drug designed to treat the underlying cause of type 1 diabetes has begun in Australia. University of Queensland researcher Ranjeny Thomas said the experimental drug — dubbed ASITI-201 — was designed to retrain the immune system so it no longer attacks the insulin-producing pancreatic cells, known as beta cells. The drug, given as an injection under the skin, combines fragments of a protein found in the beta cells of people with type 1 diabetes and vitamin D to calm the immune response. She said if effective, the drug would initially be given to patients with type 1 diabetes as soon as possible after diagnosis to preserve remaining pancreatic cells and reduce the amount of insulin needed. But eventually, if screening programs can be developed to pick up people at risk of developing type 1 diabetes, it may be possible to "prevent the progression of the disease altogether". The first in-human trial of 36 participants will test the safety of the drug, but blood tests will also determine the impact of the therapy on a patient's immune system and glucose tolerance. https://www.abc.net.au/news/2025-04-29/type-1-diabetes-drug-trial-auto-immune-disease-science/105223022 XX   Diabetes deaths in the U.S. have fallen to some of the lowest rates in years, according to new preliminary figures published by the Centers for Disease Control and Prevention, reversing a surge in mortality that was seen during the COVID-19 pandemic.   There were 26.4 deaths per 100,000 people from diabetes, according to early death certificate data for the third quarter of 2024 published this month by the CDC's National Center for Health Statistics.   Death rates from diabetes peaked in 2021, according to CDC figures, at 31.1 deaths per 100,000 people for that year. Diabetes was the eighth leading cause of death in 2021. The CDC says the link between COVID-19 and diabetes may be to blame for that increase.   "Data show an increase in mortality rates for all people during the COVID-19 pandemic, and research shows that people with underlying conditions, including diabetes, are more likely to become very sick from COVID-19 and have a higher risk of hospitalization and death," Christopher Holliday, head of the CDC's Division of Diabetes Translation, told CBS News in a statement.   Holliday added that research shows the pandemic may also have made it harder for Americans to properly manage the disease, ranging from interruptions to physical activity to disruptions to routine medical care diagnosing and treating the disease.   https://www.cbsnews.com/news/diabetes-deaths-lowest-levels-years-early-cdc-figures/ XX Big news for the Eversense CGM – they have their first pump partner. Sequel Med Tech says the twist pump will integrate with Senseonics Eversense 365 continuous glucose monitor (CGM). This collaboration would make twiist the first AID system compatible with Eversense 365, the world's first and only one-year CGM. Sequel and Senseonics say they have already started their work to integrate the latest-generation, 365-day implantable sensor with twiist. They expect to make the integrated offering available in the third quarter of this year. This marks the second CGM integration for Sequel, which partnered with Abbott and its FreeStyle Libre platform earlier this year. This week we also got a peek at the packaging and delivery of the twist as the first people posted about wearing it. We'll follow up and learn more about this newest insulin pump in the us. Senseonics, meanwhile, brought the first year-long CGM to market last year, launching Eversense 365 with its global distribution partner, Ascensia Diabetes Care, in October 2024. The system also received clearance as an integrated CGM (iCGM) system, meaning it can work with compatible medical devices. Those include insulin pumps as part of automated insulin delivery systems. https://www.drugdeliverybusiness.com/sequel-senseonics-integrate-cgm-insulin-pump/ XX Medtronic has announced the U.S. Food and Drug Administration (FDA) approval for the Simplera Sync sensor for use with the MiniMed 780G system. With this approval, the MiniMed 780G system now offers more flexibility for users of the company's most advanced insulin delivery system featuring Meal Detection technology with both the Guardian 4 sensor and Simplera Sync sensor.   The Simplera Sync is a disposable, all-in-one sensor that requires no fingersticks with SmartGuard or overtape and features a simple, two-step insertion process. It is the company's newest addition to its CGM portfolio, which expands options and provides greater flexibility for users.   The MiniMed 780G system's adaptive algorithm automatically anticipates, adjusts, and corrects glucose levels every 5 minutes, 24/7 – working around the clock so users can focus on what matters. It's the only system featuring Meal Detection technology, which detects rising sugar levels and delivers more insulin as needed to help users keep glucose levels in range more often – even when users occasionally forget to dose insulin for snacks or meals or underestimate their carbs.   The system uses a “treat to target” approach and flexible glucose targets as low as 100 mg/dL, which, combined with its adaptive algorithm allows it to more closely mirror the glucose levels of someone not living with diabetes.   Real-world data of the system shows global users consistently achieve time in range above international targets of 70% when using optimal settings (active insulin time of two hours and 100 mg/dL target glucose). It is also the only system that works with the world's only infusion set that lasts up to 7 days so that users only have to change their infusion set once per week and can experience 96% fewer injections compared to multiple daily injections.   “We're committed to driving innovation that makes life easier for those living with diabetes so they can forget about their diabetes as much as possible throughout the day,” said Que Dallara, EVP and president of Medtronic Diabetes. “Our MiniMed 780G system delivers advanced diabetes technology for so many around the world, and we're excited to continue evolving this experience with expanded CGM options —including our Simplera Sync sensor, which we look forward to bringing to people living with diabetes in the U.S.”   A limited launch of the Simplera Sync sensor will begin in the U.S. in the fall of 2025. Today, the MiniMed 780G system can be used with the Guardian 4 sensor.   Like this:https://med-techinsights.com/2025/04/29/simplera-sync-sensor-for-minimed-780g-now-fda-approved/ XX Front office changes at Insulet.. The former head of Johnson & Johnson's worldwide medtech business, Ashley McEvoy will take over as president and CEO from Jim Hollingshead, who has led Insulet since 2022. In its announcement of the leadership change, Insulet said that Hollingshead and the company mutually agreed to part ways, effective immediately. McEvoy served as worldwide medtech chairman at J&J from 2018 until her departure in late 2023, the culmination of nearly 30 years at the company and several executive roles—including president of its Ethicon division and group chairman of vision and diabetes care. Since then, she has also served as a board member at Procter & Gamble. https://www.fiercebiotech.com/medtech/insulet-taps-former-jj-medtech-head-ashley-mcevoy-be-ceo XX New free mobile game launched this week to make type 1 diabetes onboarding faster easier and less overwhelming. It's called Level One.. created by Level Ex (Powered by Relevate Health), the studio behind award-winning medical games for medical professionals. Level Ex CEO Sam Glassenberg created the game after a – quote  - brutal onboarding experience when his daughter was diagnosed five years ago He says  It took a year to understand how to manage this disease. So we fixed it. We built a game that can train your brain to do it in a matter of hours." The game is launching in partnership with leading diabetes organizations Beyond Type 1 and Breakthrough T1D Play, who are integrating Level One into their outreach and educational campaigns to support newly diagnosed families worldwide. Download Level One on the App Store: https://apps.apple.com/us/app/level-one-a-diabetes-game/id6739605694 Learn more: https://playlevelone.com   https://www.prnewswire.com/news-releases/level-ex-launches-level-one-a-free-mobile-game-to-redefine-type-1-diabetes-onboarding-302440929.html XX   Collagen is widely recognized for its role in maintaining healthy skin, but its importance extends far beyond that. As the most abundant protein in the human body, collagen provides essential structure and support to nearly all tissues and organs.   Now, researchers at Carnegie Mellon's Feinberg Lab have made a major breakthrough using their novel Freeform Reversible Embedding of Suspended Hydrogels (FRESH) 3D bioprinting technique. This method enables the precise printing of soft, living cells and tissues. Leveraging this technology, the team successfully created the first-ever microphysiologic system, also known as a tissue model, constructed entirely from collagen. This advancement opens new possibilities for studying disease and engineering tissue therapies, including potential treatments for conditions like Type 1 diabetes.   Traditionally, small-scale models of human tissue, referred to as microfluidics, organ-on-chip devices, or microphysiologic systems, have been fabricated using synthetic materials such as silicone rubber or plastics. These materials were necessary due to limitations in earlier manufacturing techniques. However, because they are not biologically native, they fail to fully replicate natural tissue environments, restricting their effectiveness in biomedical research and therapeutic development.   “Now, we can build microfluidic systems in the Petri dish entirely out of collagen, cells, and other proteins, with unprecedented structural resolution and fidelity,” explained Adam Feinberg, a professor of biomedical engineering and materials science & engineering at Carnegie Mellon University. “Most importantly, these models are fully biologic, which means cells function better.”   Building Complex Tissues with FRESH Bioprinting In new research published in Science Advances, the group demonstrates the use of this FRESH bioprinting advancement, building more complex vascularized tissues out of fully biologic materials, to create a pancreatic-like tissue that could potentially be used in the future to treat Type 1 diabetes. This advancement in FRESH bioprinting builds on the team's earlier work published in Science, by improving the resolution and quality to create fluidic channels that are like blood vessels down to about 100-micron diameter.   “There were several key technical developments to the FRESH printing technology that enabled this work,” described Daniel Shiwarski, assistant professor of bioengineering at the University of Pittsburgh and prior postdoctoral fellow in the Feinberg lab. “By implementing a single-step bioprinting fabrication process, we manufactured collagen-based perfusable CHIPS in a wide range of designs that exceed the resolution and printed fidelity of any other known bioprinting approach to date. Further, when combined with multi-material 3D bioprinting of ECM proteins, growth factors, and cell-laden bioinks and integration into a custom bioreactor platform, we were able to create a centimeter-scale pancreatic-like tissue construct capable of producing glucose-stimulated insulin release exceeding current organoid based approaches.” https://scitechdaily.com/scientists-bioprint-living-tissues-that-could-revolutionize-diabetes-treatment/ XX Another study showing the blood sugar benefit of walking after a meal. Skeletal muscle plays a central role in glucose uptake. Exercise stimulates glucose transport into muscle cells through insulin-independent pathways, notably through the action of glucose transporter type 4 (GLUT-4), which is responsible for transporting glucose from blood to skeletal muscles.4 This means that even without a robust insulin response, physical activity can facilitate glucose clearance from the bloodstream. These effects also occur without requiring high-intensity exercise, making postprandial walking accessible to a broad range of individuals, including those with limited exercise tolerance. multiple studies show that starting activity within 30 minutes after a meal is optimal. https://www.news-medical.net/health/Walking-After-Meals-Small-Habit-Big-Metabolic-Gains.aspx XX Dexcom brings back Dexcom U for a 4th years. This is a name, image and license program for college athletes with diabetes and includes a nationwide open call for passionate and inspiring college athletes to join its roster. Now through May 23, athletes, coaches, friends and family members can nominate candidates through an online submission. Those selected, along with the eight returning athletes from last year, will be invited to attend the Dexcom U Signing Day Camp this summer, hosted by Dexcom Warrior and Baltimore Ravens tight end Mark Andrews. https://www.hmenews.com/article/dexcom-u-returns-for-fourth-season

Show Notes Episode 491: You Want A NEW Drug? Part 1 of the Crack Epidemic This week Host Dave Bledsoe found himself unexpectedly in a serious situation when we staggered into an Irish wake and had to pretend he was cousin Eamon from Cork. (He was quickly figured out because his fake Irish accent kept sounding more Jamaican.) On the show this week we unexpectedly found ourselves tackling a topic way more serious than this dumb show should be allowed, the Crack Epidemic. Along the way we discover that Dave was a tattle tale growing up and then dive right into the backstory of crime in the 70s, 80's and 90s. (This is where everything started going wrong.) Then we learn how someone (could be kids from Barbados could be kids from Berkeley, or the CIA) learned how to make crack from stuff in your cleaning cabinet.  We take a look at the economic and social conditions that made the crack trade so popular in the inner city. (This is where shit got real) before laying out crack's real top customers.  (White people, surprise!) Then we look at the impact of crack on the communities that sold it. That is when the show became a two-parter. Our Sponsor this week is Clean Cut Baking Soda, don't step on your product dirty, use Clean Cut!  We open with Bette Midler telling kids that crack is whack and close with The Comatose Brothers seeking a second pharmaceutical opinion. Show Theme: Hypnostate Prelude to Common Sense The Show on Bluesky: https://bsky.app/profile/whatthehellpodcast.bsky.social The Show on Facebook: https://www.facebook.com/whatthehellpodcast/ The Show on Youtube:  https://www.youtube.com/channel/UCjxP5ywpZ-O7qu_MFkLXQUQ The Show on Instagram: https://www.instagram.com/whatthehellwereyouthinkingpod/ Our Discord Server: https://discord.gg/kHmmrjptrq Our Website: www.whatthehellpodcast.com Patreon:  https://www.patreon.com/Whatthehellpodcast The Show Line: 347 687 9601 Closing Music: https://youtu.be/h8aBWQATw1w?si=2J7w7W9ZlppzyEfL Buy Our Stuff: https://www.seltzerkings.com/shop Citations Needed: Crack Cocaine Fast Facts https://www.justice.gov/archive/ndic/pubs3/3978/index.htm Crack: A cheap and deadly cocaine is a fast-spreading menace https://time.com/archive/6706314/crack-a-cheap-and-deadly-cocaine-is-a-fast-spreading-menace/ The Severely-Distressed African American Family in the Crack Era: Empowerment is not Enough  https://pmc.ncbi.nlm.nih.gov/articles/PMC2565489/pdf/nihms-66258.pdf An Era of Drug Destruction: From Heroin to Crack Cocaine https://collaborativehistory.gse.upenn.edu/stories/era-drug-destruction-heroin-crack-cocaine Are the Wages of Sin $30 an Hour? Economic Aspects of Street-Level Drug Dealing https://journals.sagepub.com/doi/10.1177/0011128792038004005?icid=int.sj-full-text.similar-articles.7 Cocaine in the 1980s https://opentextbooks.clemson.edu/hlth4000holcombtugman/chapter/cocaine-in-the-1980s/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Send us a textIn this episode of Going Under: Anesthesia Answered with Dr. Brian Schmutzler, Brian and Vahid talk about a new drug that has surfaced in the medical industry that could be a breakthrough in how doctors treat pain. Could this be a game-changer and change the way physicians administer opioids?Have a question for Dr. Brian Schmutzler? Submit them to any of the social media pages below or on his website at https://www.drbrianschmutzler.com/Facebook: https://www.facebook.com/drbrianschmutzlerInstagram: https://www.instagram.com/drbrianschmutzlerTikTok: https://www.tiktok.com/@drbrianschmutzler?lang=enProvider or Medical Student?? Subscribe to his Patreon Page to get exclusive content and access to Medical Blocks:https://www.patreon.com/user?u=89356957&utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=creatorshare_creator&utm_content=join_linkThanks to our show sponsor: Butterfly Networkhttps://store.butterflynetwork.com/us/en/?rsCode=BRIAN25Support the show

Important Info on a New Drug and Trending With T full 1353 Thu, 24 Apr 2025 15:00:52 +0000 wS14IvWywYMJZPr3ugqCRlMsIPt4hTla news,a-newscasts,top picks The Big K Morning Show news,a-newscasts,top picks Important Info on a New Drug and Trending With T The Big K Morning Show 2024 © 2021 Audacy, Inc. News News News News news News News News News News False https://player.amperwavepodcasting.com?feed

Protecting Kids from the Dangers of Pornography   In this episode, Andy discusses the protection of children from the dangers of pornography with Parker Hymas, Director of Public Outreach at Fight The New Drug. They take a hard look into the different ways children might be exposed to porn, the impacts it has on their mental health and behavior, and effective strategies for parents to have open conversations about this sensitive issue. Additionally, they discuss the impact of platforms like OnlyFans on modern society and self-exploitation.   For more from Fight The New Drug: https://fightthenewdrug.org Take control of your data with DeleteMe. Because they sponsor the podcast you can get 20% off a privacy plan from DeleteMe with promo code: DAD.  Level Up your parenting with my ebook about protecting your kids while gaming online. Connect

Some hugely profitable drugs are targeted under new price controls. Big Pharma has been spending millions to fight them tooth and nail.Order Sharyl's new bestselling book: “Follow the $cience.” Subscribe to my two podcasts: “The Sharyl Attkisson Podcast” and “Full Measure After Hours.” Leave a review, subscribe and share with your friends! Support independent journalism by visiting the new Sharyl Attkisson store.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Professor Michael Barry, Clinical Director of the National Centre for Pharmacoeconomics

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A survivor of abuse in state care is worried new drug-driving laws mean he could be banned from taking the wheel due to his use of medicinal cannabis. Toni Jarvis says he uses prescribed products to ease his PTSD, which stems from his abuse, and he now feels like the state is after him again. Jimmy Ellingham reports.

United Cancer Advocates Network is a newly formed group of cancer advocates who are pushing for better access to cutting edge drugs in Ireland.Chairperson Miriam Staunton joins The Last Word to discuss the challenges Irish cancer patients can face in getting access to new treatments.Catch the full chat by pressing the 'Play' button on this page!

Is pornography just a private matter—or is it rewiring our kids' brains, damaging relationships, and fueling exploitation? In this urgent and eye-opening episode of The 1000 Hours Outside Podcast, Ginny Yurich speaks with Parker Hymas from Fight the New Drug, a non-religious, non-legislative organization dedicated to exposing the harmful effects of porn through science, facts, and personal accounts. Together, they dive into what makes today's porn fundamentally different from past generations, how early exposure (sometimes as young as age 7) is shaping children's mental health and relational expectations, and why conversations—not just filters—are the true solution. Parker breaks down the research, offers hope for healing, and shares practical tools for parents, educators, and anyone who cares about kids. If you've been avoiding this topic, this is the episode you can't afford to miss. ** All Fight the New Drug resources are free!! Learn more about Fight the New Drug and all they have to offer here Bring Fight the New Drug to your organization by going here Parents, find special resources just for you from Fight the New Drug here Learn more about your ad choices. Visit megaphone.fm/adchoices

A new drug shows signs of delaying Alzheimer's symptoms in those who are genetically predisposed to the disease and a surprising skeleton discovery could rewrite our history of the pyramids. Plus, On This Day in History, the first cherry blossom trees are planted in Washington D.C. Anti-amyloid drug shows signs of preventing Alzheimer's dementia | ScienceDaily Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove it | AP News Strange skeleton discovery could rewrite our history of the pyramids | BBC Science Focus Magazine Japanese cherry trees planted along the Potomac | March 27, 1912 | HISTORY Mrs. Taft and the Cherry Blossoms - White House Historical Association Sponsored by Factor -use code coolstuff50off to get 50% off your first box plus free shipping.  Contact the show - coolstuffcommute@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Biosimilars have been around for nearly a decade, but with Humira's list price of around $7,000, biosimilars for the drug are making an incredible splash in the pharmacy industry. With several biosimilars already launched in 2025 and more in the pipeline, many plan sponsors are wondering how to navigate the integration of these products into their pharmacy benefit strategies.   In this episode, Employers Health's Mike Stull chats with Jeff Casberg, head of clinical pharmacy at IPD Analytics to discuss all things biosimilars, including how biosimilar launch dates and pricing are determined, cost savings associated with these products, the importance of biosimilar formulary positioning and more.    Want to hear more from Jeff? Join us at the Annual Benefits Forum April 22-23 in Columbus, Ohio, where he'll present "The Impact of New Drugs and Therapies on PBM Spend." 

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “CRISPR breakthroughs: New solutions for common diseases” and “Re-assessing the risks of drug-induced arrhythmias during drug discovery”.  In the first article, Rolf Turk, Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. In the second article, Dr Mark Treherne, Dr Jack Scannell and Dr Richard Saumarez answer the question: Can potentially lethal arrhythmias induced by novel drugs be better predicted by using more relevant and sophisticated electrophysiological screening methods?

Friends, there is so much great information in this episode! I am thrilled to share it with you. Today I get to talk with Parker Hymas of Fight the New Drug. I didn't think I could be a bigger fan of this organization but after this episode, I am!! They are not fighting porn in a timid and embarrassed way. They are bold and brave in their message. But also speak with compassion and true care for anyone caught in the web of porn consumption. What they really want is to inspire change by educating people about the harm porn does. This episode is extra helpful if you have older teens or young adutls.  In this episode we talk about how porn harms everyone and no one is immune to it, that many teens and young adults turn to porn for their sex education and that no one has ever told them that porn is not real but also that it is harmful. Fight the New Drug is all about education so they remind us that the best thing we parents can do is talk to our kids about porn.  And I know a book that will give you all the help you need for that! I wrote It's Time to Talk to Your Kids About Porn and you can purchase it right here. You don't have to have those conversations alone.  Where to find Fight the New Drug: Find their website here Find their info for parents here Get Fast Facts to share with your teens/young adults here Find out about the live events here Listen to their podcast here Watch their videos on You Tube here Find them on Instagram here  The Greta Eskridge Podcast is a part of the Christian Parenting Podcast Network. For more information visit www.ChristianParenting.org

What if understanding the effects of pornography could empower people to make healthier choices? In this episode, I speak with Parker Hymas from Fight the New Drug, a nonprofit dedicated to raising awareness about the harmful effects of pornography through research, facts, and personal stories. Parker dives into the organization's mission to educate people — especially young audiences — on how porn impacts the brain, mental health, and society. The conversation explores the rise in pornography consumption during COVID-19, its broader societal effects, and the critical role parents play in guiding their children toward healthier habits.Links Discussed in This Episode |Book: Good Pictures, Bad Pictures Jr. by Kristen JensonJo Robertson Episode (Fight the New Drug)TEDx Talk—Tips from a Sex Therapist on Talking to Your Kids About PornConnect with Fight the New Drug:Instagram: https://www.instagram.com/fightthenewdrug/ Website: https://fightthenewdrug.org/parents/Parent Resources: ftnd.org/parentsGeneral Resources: ftnd.org/resourcesFast Facts: ftnd.org/fastfactsDocumentary: ftnd.org/bhwPodcast: ftnd.org/podcastAbout Parker Hymas |Parker Hymas is the Director of Public Outreach at Fight the New Drug, which is a non-religious, non-legislative, educational organization that works with experts, researchers, celebrities, professional athletes, award-winning journalists, CEOs, authors, influencers, and advocates from across all industries to share about the harms of pornography, and how we can address it in our society.Episode Sponsors |The Minimalist Moms Podcast would not be possible without the support of weekly sponsors. Choosing brands that I believe in is important to me. I only want to recommend brands that I believe may help you in your daily life. As always, never feel pressured into buying anything. Remember: if you don't need it, it's not a good deal!Enjoy the Podcast?Post a review and share it! If you enjoyed tuning into this podcast, then do not hesitate to write a review. You can also share this with your fellow mothers so that they can be inspired to think more and do with less. Order (or review) my book, Minimalist Moms: Living & Parenting With Simplicity.Questions |You can contact me through my website, find me on Instagram, Pinterest or like The Minimalist Moms Page on Facebook.Checkout the Minimalist Moms Podcast storefront for recommendations from Diane.If you've been struggling with motivation to declutter or work through bad habits that keep you stuck, I'd love to help you achieve your goals! We'll work together (locally or virtually) to discover what areas in your life are high priority to get you feeling less overwhelmed right away.  For more info on my processes, fees, and availability please contact!Our Sponsors:* Check out Acorns: https://acornsearly.com/MINIMALIST* Check out Armoire and use my code MINIMALIST for a great deal: https://www.armoire.style* Check out Avocado Green Mattress: https://avocadogreenmattress.com* Check out Happy Mammoth and use my code MINIMALIST for a great deal: https://happymammoth.comSupport this podcast at — https://redcircle.com/minimalist-moms-podcast2093/exclusive-contentAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Reporting for duty & sharing your weekly small talk survival guide! Share these 5 funny, interesting, trending stories and see the magic of small talk unfold - build relationships with patients and bond with coworkers with these stories: 00:00 - 03:02 intro03:02 - end: 1. https://people.com/forever-21-closing-us-stores-after-filing-for-bankruptcy-second-time-116981552. https://nypost.com/2025/03/15/lifestyle/four-seasons-launches-exclusive-vacation-to-sets-where-white-lotus-was-filmed-for-wealthy-fans/3. https://www.nbcnews.com/science/space/boeing-starliner-nasa-astronauts-return-suni-williams-butch-wilmore-rcna1949264. https://www.foodandwine.com/medication-safe-grapefruit-volcani-institute-israel-116941825. https://people.com/will-smith-announces-release-date-for-first-full-length-album-in-20-years-11697678

**This episode contains talk of addiction, pornography, and problematic sexual behaviorToday we're joined by Lauren Scharmer, a licensed clinical social worker who has a specialty in treating sexual addiction. We dive into not only sexual addiction, but other forms of addiction and how any form can hinder our relationships with not only others, but ourselves and God as well. Lauren offers helpful stats, history, and advice as well as reflection on these topics.If you or anyone you know needs help, there are resources available.- Fight the New Drug: https://fightthenewdrug.org/

Thirty years ago was 1995, and oh how our nerdy hearts beat for the late 1900s! TV, Films, Books, Comics, Trends, and more discussed in this episode. Analese was 17 but following all things law and Rob was 16 but slam dancing along to Primus. Also in this episode: Amazing Ghostbusters Nerd Mail, favorite fantasy contests, all things 1995 (Windows 95, birth of eBay and Amazon, and much, much more), Deth Wizards, the age of life for progressive glasses. Post-credits mash-up of Ghostbusters and I Want a New Drug by Revartmit on YouTube. Offered for entertainment only, with all credits to original artists. Get bonus content on Patreon Hosted on Acast. See acast.com/privacy for more information.

Have you ever wondered why so many new drugs fail even after years of research and billions in investment? In this episode, we dive deep into the challenges of drug commercialization, the role of AI in pharma, and the biggest mistakes companies make before going to market.Our guest, Dan Cummings, is a leading expert in go-to-market strategy, having worked with top health tech, medtech, and biotech startups. He shares insider insights on why even successful clinical trials don't guarantee a product's success and how companies can improve their chances.We also explore:- The shocking statistics behind drug approvals - Why less than a third of new drugs in 2025 will meet expectations- The #1 mistake pharma companies make before launch - How AI is transforming drug development & commercialization - What makes some drugs cost millions of dollars, while others are much cheaper This episode is packed with industry insights, expert opinions, and bold predictions about the future of pharmaceuticals.Chapters:00:00 Introduction03:54 The Challenges of Drug Commercialization05:35 Market Access & Value-Based Pricing12:00 Predictions for 2025 Drug Approvals13:23 The Role of AI in Pharma16:59 Why Most Drug Launches Miss Expectations18:25 Lessons from Biotech Success Stories23:46 The Future of Pharma & Go-to-Market Strategies29:31 How Companies Can Improve Their Launch Success35:56 Final Thoughts & Takeaways

We already knew that many Australians are often eager consumers of illicit drugs, with Sydney sometimes referred to as a Cocaine Capital. The only place where it’s more expensive to buy cocaine, in the world, other than Australia, is Saudi Arabia. That’s how sought after it is. But our police now have a new frontier in cocaine trafficking that’s keeping them on their toes. Today, crime reporter Sally Rawsthorne on the most fearsome drug cartels that are using submarines and other methods, to bring massive amounts of cocaine into Australia. Subscribe to The Age & SMH: https://subscribe.smh.com.au/See omnystudio.com/listener for privacy information.

We already knew that many Australians are often eager consumers of illicit drugs, with Sydney sometimes referred to as a Cocaine Capital. The only place where it’s more expensive to buy cocaine, in the world, other than Australia, is Saudi Arabia. That’s how sought after it is. But our police now have a new frontier in cocaine trafficking that’s keeping them on their toes. Today, crime reporter Sally Rawsthorne on the most fearsome drug cartels that are using submarines and other methods, to bring massive amounts of cocaine into Australia. Subscribe to The Age & SMH: https://subscribe.smh.com.au/See omnystudio.com/listener for privacy information.

Send us a textLee and Simon talk about becoming experts (in knitting), reducing screentime and nostalgia for things we have never experienced. Warning: episode includes SPOILERS for the film Conclave.Things covered: Knitting update from Lee, maintaining the intensity of a hobby, well-being and knitting, novices, expertise and thinking, changing sides while teaching a dance class, being the best in a (yoga) class, the slowness of learning a new skill, Lee being a slow study, knitting becoming a meditation, being distracted from stress, much less screentime, knitting in bed, spending less time on our phones is a really good thing, using a phone to talk to people, anemoia, millenials being nostalgic for the time before smartphones existed, how rare videos were in the 1990s, our conversations were not recorded, audio recording from 1977 of watching Star Wars at the cinema, the complexity of growing up with smartphones, Lee watched Conclave (his homework) -- WARNING spoilers included (but not written here), Gabrielle Eastwood-Ellis as a woman in the Catholic Church, Lee finds a new Chicken Restaurant, being a chicken in Portugal, many restaurants at the bottom of Bob and Lee's road in Portugal, gentrification, Simon participates in a yoga class, consent to touch in a yoga class. Get in touch with Lee and Simon at info@midlifing.net. ---The Midlifing logo is adapted from an original image by H.L.I.T: https://www.flickr.com/photos/29311691@N05/8571921679 (CC BY 2.0)

The rise of pornography addiction is not just in the "the world" but is also on the rise within the walls of the church.All this month, Ted Shimer, found of "Freedom Fight" and the book of the same name, and Hunter House, pastor at Fellowship Bentonville, join Susan to discuss the root of porn addiction and the hope that freedom can be found.To Learn more about Freedom Fight and to purchase Ted's Book: The Freedom FightBarna Pornography Stats: The Barna Group: The Porn Phenomenon

The U.S. Food and Drug Administration last year pushed a November deadline back during a licensing backlog.

In this episode, TRC Healthcare editors, Sara Klockars, PharmD, BCPS, and Stephen Small, PharmD, BCPS, BCPPS, BCCCP, CNSC, discuss notable new meds of 2024. Listen in as our editors discuss several novel drugs approved in 2024...and highlight some medications now available in a new dosage form. They'll review efficacy, safety, and considerations for use with these new treatment options.  None of the speakers have anything to disclose. TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist's Letter, Pharmacy Technician's Letter, or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.Claim CreditThe clinical resources mentioned during the podcast are part of a subscription to Pharmacist's Letter, Pharmacy Technician's Letter, and Prescriber Insights: On Demand Webinar: Notable New Meds of 2024Articles: Clarify the Role of Sofpironium for HyperhidrosisWatch for Ensifentrine for COPDDon't Rush to Aprocitentan for Resistant HypertensionNew Drug for Schizophrenia Targets Muscarinic ReceptorsBe Familiar With Carbidopa/Levodopa OptionsNew Drug Overviews:Aprocitentan (Tryvio)Epinephrine Nasal Spray (Neffy)Send us a textCheck out our NEW podcasts. Rumor vs TruthYour trusted source for facts... where we dissect the evidence behind risky rumors and reveal clinical truths.Clinical CapsulesTRC editors break down the most impactful clinical developments - giving you clear, actionable takeaways in just minutes.If you're not yet a subscriber, find out more about our product offerings at trchealthcare.com. Follow, rate, and review this show in your favorite podcast app. Find the show on YouTube by searching for ‘TRC Healthcare' or clicking here. You can also reach out to provide feedback or make suggestions by emailing us at ContactUs@trchealthcare.com.

Are AI Agents and Robots Taking Over Jobs—and Extending Our Lifespan?What if AI agents could book your flights, manage your work, and even double the human lifespan? From jaw-dropping advancements in autonomous agents to robots sprinting at Olympic speeds, this week's AI news is both thrilling and unnerving.Transform your business with AI? Don't miss the AI Business Transformation Course. Use the promo code LeveragingAI100 for $100 off the next cohort starting February 17th. https://multiplai.ai/ai-course/ In this episode of the Leveraging AI podcast, we dive into OpenAI's latest release, "Operator," a groundbreaking tool that mimics human actions to complete tasks on your browser. We also explore Perplexity's AI assistant, revolutionary breakthroughs in robotics, and predictions from leading AI thinkers about a world where humans and AI coexist in the workplace—and beyond.In this session, you'll discover:How OpenAI's "Operator" redefines the role of personal and professional assistants.The growing impact of robotics on industries—and what it means for blue-collar jobs.How AI breakthroughs might enable humans to live beyond 150 years.What business leaders can learn from Salesforce's CEO about adapting to an AI-driven workforce.Real-world AI applications transforming education, healthcare, and workplace efficiency.The challenges facing AI adoption, from regulation to trust, and how to navigate them. If you found this episode valuable, please rate, review, and share it with others who want to stay ahead in the AI revolution. Don't forget to connect with your host, Isar Meitis, on LinkedIn for ongoing insights into leveraging AI for growth and innovation.About Leveraging AI The Ultimate AI Course for Business People: https://multiplai.ai/ai-course/ YouTube Full Episodes: https://www.youtube.com/@Multiplai_AI/ Connect with Isar Meitis: https://www.linkedin.com/in/isarmeitis/ Free AI Consultation: https://multiplai.ai/book-a-call/ Join our Live Sessions, AI Hangouts and newsletter: https://services.multiplai.ai/events If you've enjoyed or benefited from some of the insights of this episode, leave us a five-star review on your favorite podcast platform, and let us know what you learned, found helpful, or liked most about this show!

Some hugely profitable drugs are targeted under new price controls. Big Pharma has been spending millions to fight them tooth and nail.Order Sharyl's new bestselling book: “Follow the $cience.” Subscribe to my two podcasts: “The Sharyl Attkisson Podcast” and “Full Measure After Hours.” Leave a review, subscribe and share with your friends! Support independent journalism by visiting the new Sharyl Attkisson store.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of More Than Roommates, Derek and Scott interview Layton & Chelsea Boeve from the Liberator Podcast as they share their story about pornography and how it's affected their marriage. Layton and Chelsea share how their story has not become their ministry as they seek to help couples with similar stories. Scriptures:1 Corinthians 6:182 Timothy 1:7Psalm 139:23-24 Resources:Podcast – Liberator Podcast (with Layton & Chelsea)Websites – Fight the New Drug and Truth About PornStudy & Website – Beyond the Porn Phenomenon Questions to Discuss:What are some topics you don't like to discuss with your spouse?What encouraged you most from Layton & Chelsea's story?What steps are you taking in your marriage to fight temptations with lust and pornography?

AP correspondent Haya Panjwani reports on new drugs selected for Medicare's price negotiations.

During Winter's Challenges, Iain Beardsell and Simon Carley reviewed the November 2024 blog posts for St Emlyn's podcast, marking the start of 2025. They discuss the busy state of emergency departments, critical incidents, and the importance of maintaining a learning culture. They highlight the upcoming Big Sick Conference in Zermatt and the IncrEMentuM in Spain, noting their potential benefits for networking and education. Simon emphasizes creating a psychologically safe environment and fostering curiosity, growth, and knowledge-sharing among emergency department staff. They also review a range of medical studies, including those on small bore vs. large bore chest tubes for haemothorax, intra-arrest arterial blood pressure monitoring, and the new GLP-1 receptor antagonists for obesity treatment. Lastly, they address the importance of handling bad behavior in the team and maintaining kindness and professionalism, even during high-stress periods. 00:00 Introduction and New Year Greetings 00:35 Current State of Emergency Departments 01:17 Upcoming Conferences: The Big Sick and IncrEMentuM 03:43 Building a Learning Culture in Emergency Medicine 12:24 Pre-Hospital ECPR and ECMO 13:58 Small Bore vs Large Bore Chest Tubes 17:37 Intra-Arrest Arterial Blood Pressure Monitoring 24:01 New Drugs and Toxicology 24:47 Care in the Hot Zone 27:12 Addressing Bad Behaviour in Emergency Departments 30:42 Conclusion and Future Plans for St Emlyn's

A review of the FDA’s drug approvals of 2024 shows that small companies loomed large—both in the sheer number of nods gained and the significance of the new drugs and biologics that these firms are bringing to the market. In this week’s episode of “The Top Line,” we take a deep dive into the FDA’s list of drugs that were approved in 2024. Fierce Pharma’s Kevin Dunleavy and Eric Sagonowsky discuss why biotechs emerged with more approvals than large drugmakers and which new drugs figure to have the most impact for patients. To learn more about the topics in this episode: 2024 drug approvals: Small companies loom large with several key FDA nods For Bristol Myers Squibb's newly approved schizophrenia drug, what a long, strange trip it's been 2023 drug approvals: After a down year, FDA signs off on a bounty of new meds, including 7 from Pfizer This episode is brought to you by Cencora. Learn more at cencora.com/breakthrough.See omnystudio.com/listener for privacy information.

As "The Veterinary Viewfinder" podcast enters its ninth year, co-hosts Dr. Ernie Ward and Beckie Mosser, MPA, RVT, reflect on what's ahead for veterinary medicine in 2025. In this special year-end episode, they highlight emerging trends and topics poised to shape the profession. The duo discusses the groundbreaking passage of Colorado's Proposition 129, introducing mid-level veterinary practitioners known as Veterinary Professional Associates (Veterinary PAs) and its implications nationwide. They also explore the expanding role of artificial intelligence in diagnostics, exam conversation transcription, client communications, and patient monitoring, emphasizing its potential to enhance—not replace—veterinary professionals. Other key topics include emerging controversies over monoclonal antibody therapeutics and new monoclonal antibody drugs entering the dermatology and pain management markets, advancements in wearable pet technology, and the evolving landscape of veterinary continuing education. The hosts address how shifts in conference attendance and online CE access are transforming professional development. Tune in for a concise, engaging look at the issues that will dominate veterinary conversations in 2025. Whether you're curious about AI, new legislative movements, or the future of veterinary pharmaceuticals and educational conferences, this episode is packed with insights to help you stay ahead in your practice. If you enjoy our podcast, please leave us a 5-star review on Apple Podcasts or your preferred platform. Your support helps us connect with more veterinary colleagues. We'd love to hear your thoughts on this topic! #veterinary #veterinarytechnician #veterinary #podcast #veterinarypodcast #vettechpodcast #vetpodcast

Looking back at new approvals from 2024 - what to keep, re-gift, or return? And yes, as soon as this was recorded 2 new drugs were approved.

There's a big potential for the untapped Indian games industry. Why hasn't it taken off yet? Is 2025 finally the year of the Indian games industry?Former Bond girl Gemma Arterton thinks James Bond can't be genderbent. Someone out there will probably take that as a challenge.A group of scientists working with school students have identified a cytotoxic chemical found in goose feces. Really. It'll take a lot of work to convince people to rub it on their cancer though.Gaming potential in India- Why gaming is India's "new entertainment frontier" | GamesIndustry.biz Genderbent 007 is not possible- 'Quantum Of Solace' Star And Former Bond Girl Gemma Arterton Disagrees With Idea Of Gender-Swapping 007: "Isn't A Female James Bond Like Mary Poppins Being Played By A Man?" - Bounding Into Comics A new antibiotic from goose shit...- Discovery of New Cyclic Lipodepsipeptide Orfamide N via Partnership with Middle School Students from the Boys and Girls Club | ACS Omega Full Show Notes : https://docs.google.com/document/d/1Paun3E2y41-dJkBmlgEv6kXbpeYucGIfEPh7c_QOtCc/edit?usp=sharing Follow us onFacebook Page - https://www.facebook.com/NerdsAmalgamated/Twitter - https://twitter.com/NAmalgamatedSpotify - https://open.spotify.com/show/6Nux69rftdBeeEXwD8GXrSiTunes - https://itunes.apple.com/au/podcast/top-shelf-nerds/id1347661094Instagram - https://www.instagram.com/nerds_amalgamated/Youtube - https://www.youtube.com/@nerdsamalgamated142TikTok - https://www.tiktok.com/@nerdsamalgamated Hosted on Acast. See acast.com/privacy for more information.

Dr. Adrian Quartel, Chief Medical Officer at Zevra Therapeutics, has received FDA approval for their drug MIPLYFFA in combination with miglustat, the first treatment in the US for Niemann-Pick type C, an ultra-orphan disease. This hard to diagnose, rare genetic lysosomal storage disorder affects the recycling of cholesterol and lipids in cells, leading to neurological and physical problems. The Amplify Assist program has been set up to help patients access and afford the treatment. Adrian elaborates, "Niemann-Pick C is a very rare or ultra-orphan disease. It's one of what is considered a lysosomal storage disorder. I'll try to explain a little bit about what that means. So lysosomes are little organelles or little systems within the cell that are basically the waste disposal system from the cell. They break down worn-out parts on the inside of the cells, or they break down harmful molecules and waste products. They're effectively recycling materials in the cell. So, any lysosomal storage disorder actually affects the system where waste products are recycled within the cell. In Niemann-Pick C disease, it's specific for lipids such as cholesterol or sphingolipids inside the cell that need to be recycled."   "The early onset of the late infantile onset usually occurs before the age of 10. Then, you have the juvenile and adult-onset, which usually occurs after the age of 10 and have different types of symptoms. Once you have the neurological symptoms, they usually start with delay in motor milestones in the younger children. But most often, we see a diagnosis happening between the ages of, say, three and seven, starting with problems in walking, stability or gait problems, clumsiness, delay in speech, or losing the ability to speak appropriately, as well as seizures, problems at school, problems to follow direction at school, some behavioral problems." #ZevraTherapeutics #RareDisease #OrphanDisease #NiemannPick #NPC #NiemannPickAwareness #PediatricRareDisease zevra.com Download the transcript here

Dr. Adrian Quartel, Chief Medical Officer at Zevra Therapeutics, has received FDA approval for their drug MIPLYFFA in combination with miglustat, the first treatment in the US for Niemann-Pick type C, an ultra-orphan disease. This hard to diagnose, rare genetic lysosomal storage disorder affects the recycling of cholesterol and lipids in cells, leading to neurological and physical problems. The Amplify Assist program has been set up to help patients access and afford the treatment. Adrian elaborates, "Niemann-Pick C is a very rare or ultra-orphan disease. It's one of what is considered a lysosomal storage disorder. I'll try to explain a little bit about what that means. So lysosomes are little organelles or little systems within the cell that are basically the waste disposal system from the cell. They break down worn-out parts on the inside of the cells, or they break down harmful molecules and waste products. They're effectively recycling materials in the cell. So, any lysosomal storage disorder actually affects the system where waste products are recycled within the cell. In Niemann-Pick C disease, it's specific for lipids such as cholesterol or sphingolipids inside the cell that need to be recycled."   "The early onset of the late infantile onset usually occurs before the age of 10. Then, you have the juvenile and adult-onset, which usually occurs after the age of 10 and have different types of symptoms. Once you have the neurological symptoms, they usually start with delay in motor milestones in the younger children. But most often, we see a diagnosis happening between the ages of, say, three and seven, starting with problems in walking, stability or gait problems, clumsiness, delay in speech, or losing the ability to speak appropriately, as well as seizures, problems at school, problems to follow direction at school, some behavioral problems." #ZevraTherapeutics #RareDisease #OrphanDisease #NiemannPick #NPC #NiemannPickAwareness #PediatricRareDisease zevra.com Listen to the podcast here

For the millions of dogs suffering from skin allergy conditions, there's a new drug…

Welcome to The Culture Translator podcast, today, we're reposting our conversation with Parker Hymas from Fight the New Drug. Parker is the Director of Public Outreach at Fight the New Drug, which is a non-religious, non-legislative, educational organization that works with experts, researchers, celebrities, professional athletes, award-winning journalists, CEOs, authors, influencers, and advocates from across all industries to share about the harms of pornography, and how we can address it in our society.  For more parenting resources, go to axis.org 

Derek Greenwood is an adjunct faculty member at Columbia Gorge Community College and a certified drug and alcohol counselor. As someone with lived experience, he credits having a safe space he could go to socialize when he was recovering from drug addiction as a young adult. But finding safe, sober spaces to form those connections with other people in recovery can be a challenge, especially in rural communities.  That challenge motivated Greenwood and others to launch an effort to help people recovering from drugs and alcohol in the Columbia Gorge. As first reported in the Oregon Capital Chronicle, the Gorge Recovery Center received a $2 million grant this summer from the state’s opioid settlement funds. The center, which does not yet have a physical location, is expected to open sometime next year. It will offer an array of services seven days a week, from peer support mentors to recreational opportunities and classes on parenting, financial literacy and other life skills. Joining us to talk about their plans and the challenges of navigating recovery in a rural community are Gorge Recovery Center board president Derek Greenwood and fellow board member Katrina Mace, who also works as a drug and alcohol counselor at Mid-Columbia Center for Living

Holmberg's Morning Sickness - Wednesday October 16, 2024 Learn more about your ad choices. Visit podcastchoices.com/adchoices