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LOGAN'S LAMENT AND THE CASE OF MISTAKEN IDENTITY Colleague Robert G. Parkinson. Host John Batchelor introduces Professor Robert G. Parkinson and his book, Heart of American Darkness, which investigates the complex relationship between colonials and Native Americans in 1775. The discussion focuses on a famous document known as "Logan's Lament," published in the Pennsylvania Journal, in which a Mingo leader named Loganblames a "Colonel Cresap" for the cold-blooded murder of his family. Parkinson clarifies that this was a case of mistaken identity; Logan confused the father, Thomas Cresap, with the son, Michael, though neither was the actual killer. NUMBER 1
BEWILDERMENT, THE OHIO COMPANY, AND COLONIAL EXPANSION Colleague Robert G. Parkinson. Parkinson explains that "bewilderment" is the central theme of his book, drawing a thematic parallel to Joseph Conrad'sHeart of Darkness to describe the confusion and violence of the early American frontier. The conversation shifts to the Ohio Company, a massive land speculation venture involving George Washington and the Lee family, with the Cresapfamily serving as their essential partners and scouts. Washington frequently visited the Cresaps in Oldtown, Maryland, utilizing them as the "spear point" for English colonial expansion into the Ohio Valley, a move that agitated the Frenchand Indigenous tribes. NUMBER 2
THE YELLOW CREEK MASSACRE AND THE TRUE PERPETRATORS Colleague Robert G. Parkinson. This segment details the chaotic environment following the British withdrawal from Fort Pitt, which created a power vacuum and a border war between Pennsylvania and Virginia. Amidst this tension, the Yellow Creek massacre occurred on April 30, 1774, where settlers lured Logan's family—including his mother, brother, and sister—into a tavern and murdered them. Parkinson confirms that Michael Cresap was not present during the slaughter; he had retreated to Catfish Campdays earlier. The actual perpetrators were men like Daniel Greathouse, not the Cresaps, though Logan remained unaware of this. NUMBER 3
LORD DUNMORE'S WAR AND CRESAP'S PATRIOT TURN Colleague Robert G. Parkinson. Following the massacre, Logan abandons diplomacy for vengeance, killing nearly twenty people and provoking Lord Dunmore's War. Simultaneously, the Continental Congress calls for rifle companies to join the revolution in Boston, and Michael Cresap is surprisingly tapped to lead a Maryland unit. Parkinson notes the irony that Cresap, previously blamed for frontier violence, becomes a patriot leader, serving alongside Daniel Greathouse, a true perpetrator of the Yellow Creekmassacre. Eventually, Logan sues for peace via his famous lament, declaring his vengeance satisfied and ending his personal war against Virginia. NUMBER 4
CRESAP'S RIFLEMEN, DEATH IN NEW YORK, AND A HERO'S FUNERAL Colleague Robert G. Parkinson. Michael Cresap leads his riflemen to Boston, fueled by press coverage depicting them as America's invincible "secret weapons" against the British. However, upon arrival, the troops prove undisciplined, leading George Washington to regret their presence. Suffering from illness, likely malaria, Cresap attempts to return home but dies in New York City in October 1775. To bolster the Patriot cause, New York provides Cresap with a massive hero's funeral, transforming the controversial frontiersman into a martyr and effectively erasing his complex, violent history in favor of a patriotic narrative. NUMBER 5
THE TRAGIC FATE OF LOGAN AND JEFFERSON'S DISCOVERY Colleague Robert G. Parkinson. The narrative reveals the tragic fate of the Mingo leader, Logan. In 1794, a surveyor encounters a Native American who admits to killing his uncle, Logan, near Lake Erie around 1780. The nephew explains that Logan had become too powerful and unpredictable a figure during the Revolutionary War, necessitating his silence. The discussion then moves to Thomas Jefferson, who discovers "Logan's Lament" while writing Notes on the State of Virginia, intending to use the speech to demonstrate Indigenous intellect and refute European claims of American degeneracy, regardless of the text's factual errors. NUMBER 6
JEFFERSON, LUTHER MARTIN, AND THE CANONIZATION OF A FALSE ACCUSATION Colleague Robert G. Parkinson. Thomas Jefferson publishes "Logan's Lament" to argue against French theories of Americaninferiority, but in doing so, he canonizes the false accusation against the Cresap family. This sparks a bitter feud with Luther Martin, a Cresap in-law, who attacks Jefferson to clear the family name. Despite the controversy, the lament becomes a staple in American education through McGuffey Readers because its tragic final line, "Who is there to mourn for Logan?", resonates with the 19th-century political narrative of the "vanishing Indian" and the concept of the "noble savage." NUMBER 7
DUELING MONUMENTS AND THE HEART OF DARKNESS THEME Colleague Robert G. Parkinson. The feud extends into the 20th century with "dueling monuments" in Ohio, where the Cresap Society and local residents erect competing memorials near the site of Logan's Elm to debate the history. Parkinson concludes by returning to the "Heart of Darkness" theme, using Conrad's metaphor of "the flicker" to describe how people create narratives like patriotism to cope with the bewilderment of their reality. He emphasizes the role of contingency, noting how the American Revolutiontransformed violent frontiersmen like Cresap into celebrated patriots while Native Americans like Logan were marginalized. NUMBER 8
JJ and Kitchen talk about Thursday Night Football, some team target share data, bold predictions, and so much more on this week's Late-Round Fantasy Football Show. Make sure to check out LateRound.com to subscribe to the free newsletter. Want to get weekly and rest-of-season rankings while accessing the amazing Late-Round community on Discord? Become a Late-Round member today.See omnystudio.com/listener for privacy information.
Brian breaks down the most misunderstood aspect of Infinite Banking: loan repayments. Why do we pay ourselves back at market rates? What does EVA actually mean? And what happens when you pay yourself more than the insurance company charges?Most people think being their own banker means they can be loose with repayment—skip payments, pay whenever, charge themselves whatever rate feels right. You can, per the contract. But should you? This episode reveals why maintaining market-rate discipline for the full loan duration is what separates wealth builders from people who just talk about IBC. Brian explains where that "extra interest" actually goes, how to decide how much to pay against your loan, and how Parkinson's Law can destroy generational wealth before it ever gets started.Discipline is what builds legacy wealth. Without it, you're just the worst kind of bank: one with no standards, no discipline, and ultimately no capital.00:00 - Opening segment00:40 - Introduction: Why loan repayments trip people up01:30 - Policy loan mechanics: you're not withdrawing, you're borrowing02:10 - Economic Value Added (EVA): the fundamental principle03:05 - Why people go sideways: thinking interest doesn't matter03:30 - Nelson Nash's recommendation: pay market rates for full duration04:40 - What "market rates" actually means05:20 - Maintaining discipline that creates wealth06:30 - The $30K car loan example at 5% over 5 years07:25 - Where does the extra interest go when you pay yourself more?08:30 - The insurance company doesn't care what rate you calculate09:30 - Should you keep paying after the loan is satisfied early?11:00 - Where most people sabotage themselves: the early payoff trap11:30 - Parkinson's Law: expenses rise to meet income12:50 - What to do when your PUAs are maxed out14:00 - Capital deployment vs. consumption: know the difference14:20 - Parkinson's Law destroys generational wealth16:00 - The temptation to "save on interest" (you're paying yourself)17:00 - "But I can make more investing elsewhere" - the speculation trap18:10 - IBC isn't about loopholes, it's about discipline19:10 - Practical implementation: set up auto-pay, treat it like any loan19:40 - The $40K truck example: paying 7% when insurance charges 5%22:30 - Decision tree when your policy is truly maxed26:15 - Income doesn't equal wealth: the $500K pilot who's broke27:00 - The $80K family building dynastic wealth28:40 - Final recap: market rates, full duration, have a plan30:00 - EVA: every loan should create value, every payment should build30:45 - If your practitioner says rates don't matter, run31:20 - The Moody Family Creed and how it applies here31:50 - Closing thoughtsEconomic Value Added (EVA): The fundamental question: did the thing you financed produce more value than the loan cost you? Borrow at 5%, asset returns 8% = positive EVA. Borrow at 5%, thing depreciates = negative EVA.Pay Yourself Market Rates: Nelson Nash recommended paying loans back at market rates or higher— at least what you'd pay elsewhere for similar financing. This maintains the discipline that creates wealth.The Full Duration Principle: Even if you pay a loan off early by using higher interest rates, keep making those payments for the full original term. A 5-year loan means 5 years of payments to your system. The Early Payoff Trap: This is where most people sabotage themselves. Visit https://remnantfinance.com for more informationFOLLOW REMNANT FINANCEYoutube: @RemnantFinance (https://www.youtube.com/@RemnantFinance )Facebook: @remnantfinance (https://www.facebook.com/profile.php?id=61560694316588 )Twitter: @remnantfinance (https://x.com/remnantfinance )TikTok: @RemnantFinanceDon't forget to hit LIKE and SUBSCRIBEChapters:Key Takeaways:Got Questions? Reach out to us at info@remnantfinance.com or book a call at https://remnantfinance.com/calendar !
Brent Kesler explains infinite banking, how he paid off nearly $1M in debt, and why the wealthy recycle money using the Money Multiplier method.In this episode of RealDealChat, Jack Hoss welcomes back Brent Kesler, founder of The Money Multiplier, to break down one of the most misunderstood wealth strategies in real estate and investing: infinite banking.Brent shares how he and his wife eliminated $984,711 of third-party debt in just 39 months—without changing cash flow, working harder, or taking on more risk. He explains how specially designed whole life policies allow investors to recycle and recapture money they're already spending, turning expenses into long-term wealth.The conversation covers the origins of the infinite banking concept (Nelson Nash), why many advisors misunderstand it, how real estate investors use it to fund deals repeatedly, and why mindset traps like Arrival Syndrome and Parkinson's Law keep people broke.If you want a proven system the wealthy have used for over 250 years—and a way to fund real estate without losing control of your money—this episode delivers clarity and conviction.
This year I have been highlighting some of local areas in the U.S. where people with Parkinson's take classes designed for their needs, provide social support, and community. It is truly magical to have this kind of central location just focused on your needs as a person with Parkinson's. Just last month we highlighted Parkinson's Body & Mind in Connecticut. They have done and continue to provide spaces where PWP can gather for exercise, wellness and community programs – all for free. If you didn't listen to that episode, check it out soon. In this episode, we talk with the co-founders of InMotion, which offers community-based wellness programs for people with Parkinson's disease. They provide this service free of charge in the greater Cleveland area and online. They talk about giving People with Parkinson's the "power to change the script "and to "feel better every day." This is a true success story, and they continue to learn and grow. Learn more by listening to this conversation with Dr. Karen Jaffe and Ben Rossi of In Motion. How might you form a similar organization in your part of the country to provide valuable wellness programs and a greater sense of community? Thank you to our sponsor – Boston Scientific, the maker of Vercise Genus, a Deep Brain Stimulation or DBS system. To learn more about the latest treatment options for Parkinson's disease at https://DBSandMe.com/17branches https://beinmotion.org/
Could human tears be the key to diagnosing Parkinson's disease? Well, that's what some New Zealander researchers are trying to find out. Parkinson's disease affects more than 12,000 New Zealanders and is the fastest-growing chronic neurological disorder in the world. New Zealander researchers are leading a world-first study looking at tears and the role they might play in early diagnosis of Parkinson's. Dr Victor Dieriks Senior Research Fellow at University of Auckland and the lead researcher for this study.
On episode 148 of PSQH: The Podcast, Dr. Peter Pronovost, Chief Quality and Transformation Officer at University Hospitals Cleveland Medical Center and Dr. Hooman Azmi of Hackensack-Meridian Health talk about improving care for patients with Parkinson's Disease.
Host Morgane Boillot chats with Dr Julia Greenland about a clinical trial of azathioprine in early Parkinson's disease. Click here to read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00386-2/fulltextContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
On November 3, 2025, the EvergreenHealth neurosciences division completed its expansion to the Monroe location and began seeing patients. Monroe-area community members can expect the same level of care they've experienced in Kirkland, now at a more convenient location closer to home. Join us as we discuss this expansion of care access with Dr. Daniel Burdick, a movement disorders and Parkinson's specialist at EvergreenHealth, and how it puts our mission to deliver patient-centered care for our community into action. Learn more about Daniel Burdick, MD
With college costs rising faster than inflation, many families feel cornered—scrambling for scholarships, stretching savings, or bracing for years of student loan payments. But there's one meaningful option that often gets overlooked: military service.For students who feel led to serve, military pathways can provide full tuition, a monthly stipend, and exceptional leadership development—all while graduating debt-free. Today, we sat down with Matt Bell, Managing Editor at Sound Mind Investing, to explore how these programs work and who they're best suited for.Matt brings a personal connection to this topic. One of his sons is currently attending the U.S. Air Force Academy, and his insight helped illuminate both the opportunity—and the responsibility—this path entails.Why Military Education Pathways Are Often MissedFor the right student, military service can be a remarkable way to fund higher education. And that qualifier matters.As Matt shared, these programs are designed for students who are willing to serve their country and take on demanding challenges. In return, the military offers generous education benefits through several primary pathways—most notably the U.S. Service Academies and the Reserve Officers' Training Corps (ROTC).Beyond the financial benefits, these programs offer leadership training and real-world experience that traditional colleges can't replicate. Matt mentioned that his son is currently choosing between summer programs such as jump school, where cadets learn to parachute, and soaring school, which involves flying gliders. Those aren't exactly typical college electives.The U.S. Service Academies: What Families Should KnowThere are five U.S. Service Academies:U.S. Military Academy (West Point)U.S. Air Force AcademyU.S. Naval AcademyU.S. Coast Guard AcademyU.S. Merchant Marine AcademyAt each academy, tuition, room, and board are fully covered, and students receive a monthly stipend. But admission is highly competitive. Some academies have acceptance rates as low as 9–10%.Applicants are evaluated holistically. Strong academic performance, high SAT or ACT scores, physical fitness, athletic participation, and demonstrated leadership all matter. Character is essential as well—letters of recommendation play a key role.And then there's one more hurdle: a nomination from a member of Congress or the Vice President (required for all academies except the Coast Guard). That process alone requires early planning and persistence.Graduates of the service academies don't walk away with a “free” education—they earn it through service.Typically, graduates commit to five years of active-duty service followed by three years in the reserves. Specific roles, such as pilots, require longer commitments—often up to ten years after specialized training.All graduates are commissioned as officers, gaining leadership experience that opens doors to a wide range of future careers, both within and beyond the military.ROTC: A Different—but Still Powerful—OptionROTC offers another pathway and is available on more than 1,700 college campuses nationwide.Unlike the academies, ROTC students experience a more traditional college environment. They typically wear uniforms one day a week rather than full-time, and they integrate military training alongside their academic studies.ROTC scholarships can cover tuition and room and board, and graduates are commissioned at the same officer rank as academy graduates. Service commitments are generally slightly shorter, but the calling to serve remains central.As appealing as debt-free college and leadership training may sound, there's a sobering reality families must weigh carefully.Choosing this path means committing to serve your country—and that includes the possibility of combat. This isn't just a financial decision or a résumé booster. It requires discernment, maturity, conviction, and a willingness to place service above self.Final ThoughtsMilitary education pathways are not for every student—but for the right one, they can be transformative. They offer freedom from student debt, unparalleled leadership development, and the opportunity to serve something greater than oneself.As families prayerfully consider college decisions, this option deserves thoughtful, informed consideration—not just for what it provides, but for what it asks in return.On Today's Program, Rob Answers Listener Questions:I have Parkinson's and will need to stop working soon. I live in a paid-off home, and I also own a beach property with a mortgage. Once I stop working, I won't be able to afford that payment. The beach home has been on the market for over a year and a half without selling. If I allow the bank to foreclose on it, what are the consequences—especially when it comes to taxes and whether it could affect my primary residence?I'm trying to understand whether a will is enough for my situation or if I need additional estate planning. I want to be sure my children receive everything I intend to leave to them.I'm taking early retirement from the government and have just over $1 million in my Thrift Savings Plan (TSP). I'm in my early 50s and plan to focus full-time on caring for my family. I want guidance on how to proceed with that money.Resources Mentioned:Faithful Steward: FaithFi's Quarterly Magazine (Become a FaithFi Partner)U.S. Military Academy (West Point) | U.S. Air Force Academy | U.S. Naval Academy | U.S. Coast Guard Academy | U.S. Merchant Marine Academy | Reserve Officers Training Corps ROTCSound Mind Investing (SMI)Wisdom Over Wealth: 12 Lessons from Ecclesiastes on MoneyLook At The Sparrows: A 21-Day Devotional on Financial Fear and AnxietyRich Toward God: A Study on the Parable of the Rich FoolFind a Certified Kingdom Advisor (CKA)FaithFi App Remember, you can call in to ask your questions every workday at (800) 525-7000. Faith & Finance is also available on Moody Radio Network and American Family Radio. You can also visit FaithFi.com to connect with our online community and partner with us as we help more people live as faithful stewards of God's resources. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Most people don't have a money problem… they have a Parkinson's Law problem. Your expenses quietly rise, your "extra" money disappears, and the timeline for big goals keeps stretching—until one day you realize you're working harder but staying in the same place.
It's a big day in Washington D.C for wolves. The House of Representatives will vote on the Pet and Livestock Protection Act. Ultimately, the decision will determine if the gray wolf will stay on the endangered species list. Fabulous Farm Babe Pam Jahnke and Wisconsin DNR Large Carnivore Specialist, Randy Johnson, discuss Wisconsin's wolf population data and movement patterns. Ag meteorologist Stu Muck and Kiley Allan talk about the warmer temperatures we have been seeing. Temperatures will continue to swing in the upcoming week. No two days as a veterinarian look the same. Dr. Monty Belmer, a local veterinarian explains the standard practices and the heightened precautions veterinarians take when a disease outbreak occurs to Stephanie Hoff. Dr. Arden Anderson, a Physician and Agricultural Consultant, tells Ben Jarboe that farmers are a high-risk group for several health concerns including cancer, heart disease, and Parkinson’s disease. He tells us one reason why the group is considered high risk.Dairy market analyst, Cody Koster, breaks down the suspected market effects of Avian Influenza. He looks into his crystal ball and forecasts the GDT trends we can expect going into the new year.See omnystudio.com/listener for privacy information.
L'un des faits les plus surprenants dans l'interprétation scientifique des rêves ne concerne ni les symboles, ni la psychanalyse, mais notre corps lui-même. De nombreuses études montrent aujourd'hui que certains rêves peuvent révéler une maladie avant même que les premiers symptômes ne se manifestent. Ce phénomène, longtemps relégué aux anecdotes, est désormais documenté par la recherche en neuropsychologie et en médecine du sommeil.L'exemple le plus fascinant vient d'une étude publiée dans The Lancet Neurology. Des chercheurs s'intéressaient au trouble du comportement en sommeil paradoxal (TCSP), une affection dans laquelle les dormeurs “vivent” leurs rêves : ils parlent, crient, donnent des coups, ou se débattent comme s'ils étaient réellement dans la scène rêvée. Ce trouble provient d'un dysfonctionnement du cerveau : durant le rêve, les muscles ne sont plus paralysés comme ils devraient l'être. Mais l'élément troublant va plus loin.Les scientifiques ont découvert que jusqu'à 80 % des personnes atteintes de ce trouble développent dans les années qui suivent une maladie neurodégénérative, notamment la maladie de Parkinson ou une démence à corps de Lewy. Le rêve devient alors un signal d'alerte neurologique, une sorte de message avant-coureur envoyé par un cerveau déjà en difficulté, bien avant l'apparition des symptômes cliniques tels que les tremblements ou les pertes de mémoire.Pourquoi ? Parce que les régions cérébrales qui contrôlent le rêve et la paralysie musculaire — notamment le tronc cérébral — sont les premières touchées par les dépôts anormaux de protéines responsables de ces maladies. Autrement dit, le cerveau annonce sa propre souffrance… dans le rêve.Un autre aspect étonnant : certains patients commencent à rêver de situations de danger extrême — être poursuivi, attaqué, agressé — alors qu'ils n'avaient jamais ce type de rêves auparavant. Ces scénarios ne traduisent pas une angoisse psychologique, mais un signal biologique : les circuits neuronaux régulant la peur deviennent instables, ce qui peut annoncer une maladie en développement.Ce phénomène bouleverse l'idée traditionnelle du rêve comme simple reflet de l'inconscient. Il montre que le rêve est aussi un outil diagnostique potentiel, capable d'indiquer des troubles invisibles à l'examen médical classique.Ainsi, l'un des faits les plus étonnants de la science du sommeil est que nos rêves peuvent parfois prédire une maladie, et le faire avec une précision qui intrigue de plus en plus les chercheurs. Le rêve n'est peut-être pas un oracle… mais il est clairement un capteur avancé de notre santé. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
2152 Parkinson’s Disease/Trump Derangement Syndrome
Dec. 18, 2025 ~ Tremor treatment is entering a transformative era. Lloyd Jackson spotlights Henry Ford neurosurgeons Dr. Deneeka Paulo and Dr. Efstathios Kondylis, who are pioneering the use of High Intensity Focused Ultrasound (HIFU) to restore quality of life for patients with essential tremor and Parkinson's disease. This FDA-approved, incision-free procedure uses precisely targeted sound waves to treat the brain areas causing tremors—all without general anesthesia or implanted hardware. Patients typically go home the same day and often notice improvement within days, enabling them to return to everyday activities like writing, eating, and holding objects. Dr. Paulo emphasizes that HIFU offers hope for those who have exhausted medications or faced undesirable side effects, providing a safe, minimally invasive alternative that can dramatically reduce symptoms and help patients reclaim independence. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dec. 18, 2025 ~ Tremor treatment is entering a transformative era. Lloyd Jackson spotlights Henry Ford neurosurgeons Dr. Deneeka Paulo and Dr. Efstathios Kondylis, who are pioneering the use of High Intensity Focused Ultrasound (HIFU) to restore quality of life for patients with essential tremor and Parkinson's disease. This FDA-approved, incision-free procedure uses precisely targeted sound waves to treat the brain areas causing tremors—all without general anesthesia or implanted hardware. Patients typically go home the same day and often notice improvement within days, enabling them to return to everyday activities like writing, eating, and holding objects. Dr. Paulo emphasizes that HIFU offers hope for those who have exhausted medications or faced undesirable side effects, providing a safe, minimally invasive alternative that can dramatically reduce symptoms and help patients reclaim independence. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dec. 18, 2025 ~ Tremor treatment is entering a transformative era. Lloyd Jackson spotlights Henry Ford neurosurgeons Dr. Deneeka Paulo and Dr. Efstathios Kondylis, who are pioneering the use of High Intensity Focused Ultrasound (HIFU) to restore quality of life for patients with essential tremor and Parkinson's disease. This FDA-approved, incision-free procedure uses precisely targeted sound waves to treat the brain areas causing tremors—all without general anesthesia or implanted hardware. Patients typically go home the same day and often notice improvement within days, enabling them to return to everyday activities like writing, eating, and holding objects. Dr. Paulo emphasizes that HIFU offers hope for those who have exhausted medications or faced undesirable side effects, providing a safe, minimally invasive alternative that can dramatically reduce symptoms and help patients reclaim independence. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
2152 Parkinson’s Disease/Trump Derangement Syndrome
In the hospital setting, neurologists may be responsible for managing common end-of-life symptoms. Comprehensive end-of-life care integrates knowledge of the biomedical aspects of disease with patients' values and preferences for care; psychosocial, cultural, and spiritual needs; and support for patients and their families. In this episode, Teshamae Monteith, MD, FAAN, speaks with Claudia Z. Chou, MD, author of the article "End-of-Life Care and Hospice" in the Continuum® December 2025 Neuropalliative Care issue. Dr. Monteith is the associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. Knox is an assistant professor of neurology and a consultant in the Division of Community Internal Medicine, Geriatrics and Palliative Care at Mayo Clinic in Rochester, Minnesota. Additional Resources Read the article: End-of-Life Care and Hospice Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @headacheMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Monteith: This is Dr Teshamae Monteith. Today I'm interviewing Dr Claudia Chou about her article on end-of-life care and hospice, which is found in the December 2025 Continuum issue on neuropalliative care. Welcome to our podcast. How are you? Dr Chou: I'm doing well. Thank you for having me. This is really exciting to be here. Dr Monteith: Absolutely. So, why don't you introduce yourself to our audience? Dr Chou: Sure. My name is Claudia Chou. I am a full time hospice and palliative medicine physician at Mayo Clinic in Rochester. I'm trained in neurology, movement disorders, and hospice and palliative medicine. I'm also passionate about education, and I'm the program director for the Hospice and Palliative Medicine fellowship here. Dr Monteith: Cool. So just learning about your training, I kind of have an idea of how you got into this work, but why don't you tell me what inspired you to get into this area? Dr Chou: It was chance, actually. And really just good luck, being in the right place at the right time. I was in my residency and felt like I was missing something in my training. I was seeing these patients who were suffering strokes and had acute decline in functional status. We were seeing patients with new diagnosis of glioblastoma and knowing what that future looked like for them. And while I went into neurology because of a love of neuroscience, localizing the lesion, all of those things that we all love about neurology, I still felt like I didn't have the skill set to serve patients where they perhaps needed me the most in those difficult times where they were dealing with serious illness and functional decline. And so, the serendipitous thing was that I saw a grand rounds presentation by someone who works in neurology and palliative care for people with Parkinson's disease. And truly, it's not an exaggeration to say that by the end of that lecture, I said, I need to do palliative care, I need to rotate in this, I need to learn more. I think this is what I've been missing. And I had plans to practice both movement disorders neurology and palliative care, but I finished training in 2020… and that was not a long time ago. We can think of all the things that were going on, all the different global forces that were influencing our day-to-day decisions. And the way things worked out, staying in palliative care was really what my family and I needed. Dr Monteith: Wow, so that's really interesting. Must have been a great lecturer. Dr Chou: Yes, like one of the best. Dr Monteith: So why don't you tell me about the objectives of your article? Dr Chou: The objectives may be to fill in some of the gaps in knowledge that may be present for the general neurologist. We learn so much in neurology training, so much about how to diagnose and treat diseases, and I think I would argue that this really is part and parcel of all we should be doing. We are the experts in these diseases, and just because we're shifting to end-of-life or transitioning to a different type of care doesn't mean that we back out of someone's care entirely or transition over to a hospice or palliative care expert. It is part of our job to be there and guide patients and their care partners through this next phase. You know, I'm not saying we all need to be hospice and palliative care experts, but we need to be able to take those first steps with patients and their care partners. And so, I think objectives are really to focus in on, what are those core pieces of knowledge for end-of-life care and understanding hospice so we can take those first steps with patients and their care partners? Dr Monteith: So, why don't you give us some of those essential points in your article? Dr Chou: Yeah. In one section of the article, I talk about common symptoms that someone might experience at the end of life and how we might manage those. These days, a lot of hospitals have order sets that talk us through those symptoms. We can check things off of a drop-down menu. And yet I think there's a little bit more nuance to that. There may be situations in which we would choose one medication over another. There may be medications that we've never really thought of in terms of symptom management before. Something that I learned in my hospice and palliative medicine fellowship was that haloperidol can be helpful for nausea. I know that's usually not one of our go-tos in neurology for any number of reasons. So, I think that extra knowledge can take us pretty far when we're managing end of life symptoms, particularly in the hospital setting. And then I think the other component is the hospice component. A lot of us may have not had experience talking about hospice, talking about what hospice can provide, and again, knowing how to take those first steps with patients. We may be referring to social work or palliative medicine to start those conversations. But again, I think this is something that's definitely learnable and something that should be part of our skill set in neurology. Dr Monteith: Great. And so, when you speak about symptom management and being more comfortable with the tools that we have, how can we be more efficient and more effective at that? Dr Chou: Think about what the common symptoms are at end of life. We may know this kind of intuitively, but what we commonly see are things like pain, nausea, dyspnea, anxiety, delirium or agitation. And so, I think having a little bit of a checklist in mind can be helpful. You know, how can I systematically think through a differential, almost, for why my patient might be uncomfortable? Why they might be restless? Have I thought through these different symptoms? Can I try a medication from my tool kit? See if that works, and if it does, we can continue on. If not, what's the next thing that I can pivot to? So, I think these are common skills for a little bit of a differential diagnosis, if you will, and how to work through these problems just with the end-of-life lens on it. Dr Monteith: So, are there any, like, validated tools or checklists that are freely available? Dr Chou: I don't think there's been anything particularly validated for end-of-life care in neurologic disease. And so, a lot of our treatments and our approaches are empiric, but I don't think there's been anything validated, per se. Dr Monteith: Great. So, why don't we talk a little bit about the approach to discussions on hospice? We all, as you kind of alluded to, want to be effective neurologists, care for our patients, but we sometimes deal with very debilitating diseases. And so, when we think that or suspect that our patient is kind of terminally ill, how do we approach that to our patients? Of course, our patients come from different backgrounds, different experiences. So, what is your approach? Dr Chou: So, when we talk about hospice and when a patient may be appropriate for hospice, we have to acknowledge that we think that they may be in the last six months of their disease. We as the neurologist are the experts in their disease and the best ones to weigh in on that prognosis. The patient and their care partners then have to accept that the type of care that hospice provides is what makes sense for them. Hospice focuses on comfort and treating a patient's comfort as the primary goal. Hospice is not as interested in treating cancer, say, to prolong life. Hospice is not as interested in life-prolonging measures and treatments that are not focused at comfort and quality of life. And so, when we have that alignment between our understanding of a patient's disease and their prognosis and the patient care partner's goal is to focus on comfort and quality of life above all else, that's when we have a patient who might be appropriate for hospice and ready to hear more about what that actually entails. Dr Monteith: And what are some, maybe, myths that neurologist healthcare professionals may have about hospice that you really want us to kind of have some clarity on? Dr Chou: That's a great question. What we often tell patients is that hospice's goal is to help patients live as well as possible in the time that they have left. Again, our primary objective is not life prolongation, but quality of life. Hospice's goal is also not to speed up or slow down the natural dying process. Sometimes we do get questions about that: can't you make this go faster or we're ready for the end. But really, we are there to help patients along the natural journey that their body is taking them on. And I think hospice care can actually be complex. In the inpatient setting, in particular in neurology, we may be seeing patients who have suffered large strokes and have perhaps only days to a few weeks of life left. But in the outpatient setting and in the home hospice setting, patients can be on hospice for many months, and so they will have new care needs, new urinary tract infections, sometimes new rashes, the need to change their insulin regimens around to avoid extremes of hyperglycemia or hypoglycemia. So, there is a lot of complexity in that care and a lot that can be wrapped up under that quality-of-life and comfort umbrella. Dr Monteith: And to get someone to hospice requires a bit of prognostication, right? Six months of prediction in terms of a terminal illness. I know there's some nuances to that. So how can you make us feel more comfortable about making the recommendations for hospice? Dr Chou: I think this is a big challenge in the field. We're normally guided by Medicare guidelines that say when a patient might be hospice-appropriate. And so, for a neurologic disease, this really only encompasses four conditions: ALS, stroke, coma, and Alzheimer's dementia. And we can think of all the other diseases that are not encompassed in those four. And so, I think we say that we paint the picture of what it means to have a prognosis of six months or less. So, from the neurologic side, that can be, what do you know about this disease and what end-stage might look like? What is the pattern of the patient's functional decline? What are they needing more help with? Are there other factors at play such as heart failure or COPD that may in and of themselves not be a qualifying diagnosis for hospice, but when it's taken together in the whole clinical picture, you have a patient who's very ill and one that you're worried may die in the next six months or less? Dr Monteith: Then you also had some nice charts on kind of disease-specific guidelines. Can you take us a little bit through that? Dr Chou: The article does contain tables about specific criteria that may qualify someone for hospice with these neurologic conditions. And they are pretty dense. I know they're a checklist of a lot of different things. And so, how we practice is by trying to refer patients to hospice based on those guidelines as much as possible and then using our own clinical judgment as well, what we have seen through taking care of patients through the years. So, again, really going back to that decline. What is making you feel uncomfortable about this patient's prognosis? What is making you feel like, gosh, this patient could be well supported by hospice, and they could have six months or less? So, all of that should go into your decision as well. And all of that should go into your discussion with the patient and their care partners. Dr Monteith: Yeah. And reading your article, what stood out was all the services that patients can receive under hospice. So, I think sometimes people think, okay, this is terminal illness, let's get to hospice for whatever reasons, but not necessarily all the lists and lists and lists of benefits of hospice. So, I don't know that everyone's aware of all those benefits. So, can you talk to us a little bit about that? Dr Chou: Yeah, I like that you brought that up because that's also something that I often say to patients and their care partners when we're talking about hospice. When the time is right for a patient to enroll in hospice, they should not feel like they're giving anything up. There should be no more clinical trial that they're hoping to chase down, and so they should just feel like they're gaining all of those good supports: care that comes to their home, a team that knows them well, someone that's available twenty-four hours a day by phone and can actually even come into the home setting if needed to help with symptom management. Hospice comes as well with the psychosocial supports for just coping with what dying looks like. We know that's not easy to be thinking about dying for oneself, or for a family member or care partner to be losing their loved one. So, all of those supports are built into hospice. I did want to make a distinction, too, that hospice does not provide custodial care, which I explain to patients as care of the body, those daily needs for bathing, dressing, eating, etc. Sometimes patients are interested in hospice because they're needing more help at home, and I have to tell them that unfortunately, our healthcare system is not built for that. And if that's the sole reason that someone is interested in hospice, we have to think about a different approach, because that is not part of the hospice benefit. Dr Monteith: Thank you for that. And then I learned about concurrent care. So why don't you tell us a little bit about that? That's a little bit of a nuance, right? Dr Chou: Yeah, that is a little bit of a nuance. And so, typically when patients are enrolling in hospice, they are transitioning from care the way that it's normally conducted in our healthcare system. So, outpatient visits to all of the specialists and to their primary care providers, the chance to go to the ER or the ICU for higher levels of care. And yet there are a subset of patients who can still have all of those cares alongside hospice care. That really applies to two specific populations: veterans who are receiving care through the Veterans Administration, and then younger patients, so twenty six years old and less, can receive that care through, essentially, a pediatric carve out. Dr Monteith: Great. Well, I mean, you gave so much information in your article, so our listeners are going to have to read it. I don't want you to spill everything, but if you can just kind of give me a sense what you want a neurologist to take away from your article, I think that would be helpful. Dr Chou: I think what I want neurologist to take away is that, again, this is something that is part of what we do as neurologists. This is part of our skill set, and this is part of what it means to take good care of patients. I think what we do in this transition period from kind of usual cares, diagnosis, full treatment to end of life, really can have impact on patients and their care partners. It's not uncommon for me to hear from family members who have had another loved one go through hospice about how that experience was positive or negative. And so, we can think about the influence for years to come, even, because of how well we can handle these transitions. That really can be more than the patient in front of us in their journey. That is really important, but it can also have wide-reaching implications beyond that. Dr Monteith: Excellent. And I know we were talking earlier a little bit about your excitement with the field and where it's going. So why don't you share some of that excitement? Dr Chou: Yeah. And so, I think there is a lot still to come in the field of neuropalliative care, particularly from an evidence base. I know we talked a lot about the soft skills, about presence and communication, but we are clinicians at heart, and we need to practice from an evidence base. I know that's been harder in palliative care, but we have some international work groups that really are trying to come together, see what our approaches look like, see where standardization may need to happen or where our differences are actually our strength. I think there can be a lot of variability in what palliative care looks like. So, my hope is that evidence base is coming through these collaborations. I know it's hard to have a conversation these days without talking about artificial intelligence, but that is certainly a hope. When you look at morbidity, when you look at patients with these complicated disease courses, what is pointing you in the direction of, again, a prognosis of six months or less or a patient who may do better with this disease versus not? And so, I think there's a lot to come from the artificial intelligence and big data realm. For the trainees listening out there, there is no better time to be excited about neuropalliative care and to be thinking about neuropalliative care. I said that I stumbled upon this field, and hopefully someone is inspired as well by listening to these podcasts and reading Continuum to know what this field is really about. And so, it's been exponential growth since I joined this field. We have medical students now who want to come into neuropalliative care as a profession. We have clinicians who are directors of neuropalliative care at their institutions. We have an international neuropalliative care society and neuropalliative care at AAN. And I think we are moving closer to that dream for all of us, which is that patients living with serious neurologic illness can be supported throughout that journey. High-quality, evidence-based palliative care. We're not there yet, but I think it is a possibility that we reach that in my lifetime. Dr Monteith: Well, excellent. I look forward to maybe another revision of this article with some of that work incorporated. And it's been wonderful to talk to you and to reflect on how better to approach patients that are towards the end of life and to help them with that decision-making process. Thank you so much. Dr Chou: Yeah, thank you for having me. And we're very excited about this issue. Dr Monteith: Today. I've been interviewing Dr Claudia Chou about her article on end-of-life care and hospice, which is found in the December 2025 Continuum issue on neuropalliative care. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.
Earlier this year, The Michael J. Fox Foundation hosted its 2025 Research Roundtable, “Building on Breakthroughs.” Tune into audio from this event to hear Parkinson's experts and MJFF staff discuss the latest in lifestyle medicine and treatments in the pipeline, as well as the power of advocating for Parkinson's policy.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson's or not, you can help move research forward. Join the study that's changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Research will move us closer to a cure for Parkinson's — but we can't do it without you. Help us accelerate more life-changing breakthroughs by visiting michaeljfox.org/givetoresearch to donate today.
5 Things You Never Learned About Pavlov's Experiments Who was "Pavlov's dog?" What is a "Pavlovian" response? Pavlov's experiments with dogs supposedly taught us about classical conditioning. Listen to today's episode from PETA.org @official.peta #vegan #plantbased #plantbasedbriefing #pavlov #pavlovsdog #vivisection #animalcruelty ========================== Original post: https://www.peta.org/features/pavlov-experiments/ Related: Test Subjects Short Film: https://lockwoodfilm.com/test-subjects The Medical Illusion Documentary: https://evotionfilms.com "Contrary to what the public is being told, we are 60 years away from cures and effective treatments for most cancers, ALS, Alzheimer's, Parkinson's and other major diseases. This poignant film explains why." ================= DOES PETA KILL ANIMALS? 395: Does PETA Kill Animals? And Other Questions About PETA's Shelter Answered. By Katherine Sullivan PETA.org https://plantbasedbriefing.libsyn.com/395-does-peta-kill-animals-and-other-questions-about-petas-shelter-answered-by-katherine-sullivan-petaorg ================= People for the Ethical Treatment of Animals (PETA) was founded in 1980, is the largest animal rights organization in the world, and PETA entities have more than 9 million members and supporters globally. PETA believes that animals have rights and deserve to have their best interests taken into consideration, regardless of whether they are useful to humans. Like you, they are capable of suffering and have an interest in leading their own lives. ============================== FOLLOW PLANT BASED BRIEFING ON: YouTube: https://www.youtube.com/@plantbasedbriefing Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing LinkedIn: https://www.linkedin.com/company/plant-based-briefing/ Instagram: https://www.instagram.com/plantbasedbriefing/
Communication skills for dating in college are essential! Dr. Victoria Vaughn, a retired educator and lifelong learner, found herself newly single at fifty-five after a thirty-year marriage. Entering the senior dating pool, she discovered not just frogs but full-suitcases of "baggage"—from the talker and the narcissist to the bully, the cheater, and more. Her memoir, "Oh the Frogs I Kissed Before I Finally Found My Prince", blends humor, honesty, and hard-won wisdom. With stories that are both entertaining and eye-opening, she invites readers to laugh, nod in recognition, and take away insights for their own dating journeys. 10% of all profits from the book will go to the Michael J. Fox Foundation for Parkinson's research. In episode 628 of the Fraternity Foodie Podcast, we find out what was the biggest shock jumping back into the dating world after 30 years of marriage, when she realized these stories could help younger adults who are also trying to navigate modern dating, what early dating behaviors signal "Frog Alert", advice for students to spot "dating profile embellishment" before it becomes a disaster, how can someone tell when substance use crosses the line into a red flag, what were the earliest signs she missed that today's students should pay attention to, why do people override their gut instinct in early dates, what role did self-respect and self-knowledge play in her eventual decision to walk away from men who were clearly wrong, what communication habits should students look for in a healthy partner, and why is it OK to go slowly. Enjoy!
In this conversation, I cover the emerging science on psychedelics. Not the hype, but the data.How these compounds interact with the brain, reopen windows of neuroplasticity, and appear to influence aging, neurodegenerative disease, mental health, trauma, and resilience in ways we're only beginning to understand.I walk through studies looking at psychedelics in neurodegenerative disease, stroke recovery, and end-of-life care, specifically improvements in Parkinson's, life extension in cells and mice, and cancer patients losing their fear of death.The thread tying all of this together is simple but uncomfortable: longevity isn't just about adding years to the body. It's about tending to the nervous system, the mind, and the stories we carry.If we want to live longer and better, we may need to stop treating biology and psychology as separate systems, and start designing a more integrated, humane approach to aging.Timestamps:00:00 Introduction to Epigenetics and Longevity02:42 The Intersection of Psychedelics and Longevity05:36 Understanding the Hallmarks of Aging08:51 Mental Health, Neuroplasticity, and Aging11:45 Psychedelics and Neurodegenerative Diseases14:46 Psychedelics in Stroke Recovery17:33 Psychedelics and Trauma Healing20:30 Psychedelics in End-of-Life Care23:41 The Future of Longevity and PsychedelicsCONNECT WITH NINA'S NOTESNewsletter: https://www.ninasnotes.xyzLinkedIn: https://www.linkedin.com/in/ninapatrick/Website: https://www.ninapatrick.xyz Get full access to Nina's Notes at www.ninasnotes.xyz/subscribe
There are at least five intriguing quarterback options with great matchups but we're not sure if we can trust guys like Kirk Cousins, Tyler Shough, Gardner Minshew and others. So, who are our top priorities (4:35) for Week 16? Colby Parkinson and Michael Carter have great opportunities ... News and notes (14:45) and Top Three priorities at each position: QB (19:15), RB (24:40), WR (26:15), TE (27:30), DST (31:00) and Kicker. We talk about Jayden Reed, Luther Burden, Bryce Young, the Saints running backs, Jaleel McLaughlin, Oronde Gadsden and more ... Options in shallow leagues (40:10) and deep leagues (49:50), a Dolphins-Steelers recap (47:10) and a longer look at the waiver wire (55:40) at each position ... Email us at fantasyfootball@cbsi.com Fantasy Football Today is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts Watch FFT on YouTube https://www.youtube.com/fantasyfootballtoday Shop our store: shop.cbssports.com/fantasy SUBSCRIBE to FFT Dynasty on Apple: https://podcasts.apple.com/us/podcast/fantasy-football-today-dynasty/id1696679179 FOLLOW FFT Dynasty on Spotify: https://open.spotify.com/show/2aHlmMJw1m8FareKybdNfG?si=8487e2f9611b4438&nd=1 SUBSCRIBE to FFT DFS on Apple: https://podcasts.apple.com/us/podcast/fantasy-football-today-dfs/id1579415837 To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
(1:00) – Jay details his experience watching Keanu Reeves on Broadway(4:25) – QB Waiver Wire: C.J. Stroud, J.J. McCarthy, Tyler Shough, Marcus Mariota, Bryce Young, Kirk Cousins(16:35) – RB Waiver Wire: Blake Corum, Michael Carter, Emari Demercado, Jacory Croskey-Merritt, Jeremy McNichols, Audric Estime, Evan Hull, Jahwar Jordan + Notable insurance backs(33:30) – WR Waiver Wire: Jayden Reed, Luther Burden III, Adonai Mitchell, Jalen Coker, Darius Slayton(38:25) – TE Waiver Wire: Dalton Schultz, Colby Parkinson, Colston Loveland, Theo Johnson, Darren Waller, Gunnar Helm(41:50) – Dolphins at Steelers Reaction: Jaylen Warren vs Kenneth Gainwell splits, disappointing game for Jaylen Waddle(50:30) – Last Call: Early-week bets on Jets-Saints and Vikings-Giants Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This is a recap of the top 10 posts on Hacker News on December 15, 2025. This podcast was generated by wondercraft.ai (00:30): Roomba maker goes bankrupt, Chinese owner emergesOriginal post: https://news.ycombinator.com/item?id=46268854&utm_source=wondercraft_ai(01:54): I'm Kenyan. I don't write like ChatGPT, ChatGPT writes like meOriginal post: https://news.ycombinator.com/item?id=46273466&utm_source=wondercraft_ai(03:18): “Super secure” messaging app leaks everyone's phone numberOriginal post: https://news.ycombinator.com/item?id=46279123&utm_source=wondercraft_ai(04:42): If AI replaces workers, should it also pay taxes?Original post: https://news.ycombinator.com/item?id=46268709&utm_source=wondercraft_ai(06:06): Pro-democracy HK tycoon Jimmy Lai convicted in national security trialOriginal post: https://news.ycombinator.com/item?id=46276740&utm_source=wondercraft_ai(07:30): Thousands of U.S. farmers have Parkinson's. They blame a deadly pesticideOriginal post: https://news.ycombinator.com/item?id=46275079&utm_source=wondercraft_ai(08:54): Carrier Landing in Top Gun for the NESOriginal post: https://news.ycombinator.com/item?id=46274822&utm_source=wondercraft_ai(10:18): Avoid UUID Version 4 Primary Keys in PostgresOriginal post: https://news.ycombinator.com/item?id=46272487&utm_source=wondercraft_ai(11:42): Secret Documents Show Pepsi and Walmart Colluded to Raise Food PricesOriginal post: https://news.ycombinator.com/item?id=46280887&utm_source=wondercraft_ai(13:07): UnsciiOriginal post: https://news.ycombinator.com/item?id=46270282&utm_source=wondercraft_aiThis is a third-party project, independent from HN and YC. Text and audio generated using AI, by wondercraft.ai. Create your own studio quality podcast with text as the only input in seconds at app.wondercraft.ai. Issues or feedback? We'd love to hear from you: team@wondercraft.ai
Waivers are heating up in Week 16! In this episode of WireTapped by Club Fantasy FFL, we break down the top waiver wire pickups you need to target before they're gone. We'll dive into:Priority waiver adds at RB, WR, QB, and TEInjury updates & next-man-up opportunitiesFantasy sleepers & low-rostered gemsAdd/drop and streamer strategy for Week 16
Many people will be familiar with Parkinson's disease: the progressive brain disorder that causes symptoms including tremors and slower movement, leading on to serious cognitive problems. You might not know that it's the fastest-growing neurological condition in the world. Today it affects around 11.8 million people and that's forecast to double by 2030. Dr Sonia Gandhi is one of the scientists working to change that trend. As Professor of Neurology at University College London and Assistant Research Director at the Francis Crick Institute, her work involves using stem cells to build models of the human brain, helping to drive the development of drugs and other therapies for Parkinson's patients. Talking to Professor Jim Al-Khalili, Sonia explains why this destructive condition is on the rise - and the promising routes they're studying to find new ways to tackle it.
On this episode Fred Goldstein invites Marty Acevedo, MS, RD, Patient Advocate and President & Board Chair of the Parkinson's Association of San Diego. Marty shares her personal journey with Parkinson's disease—from a delayed diagnosis to managing symptoms, treatment decisions, and the impact on daily life. She discusses the importance of individualized care, the essential role of caregivers, and the value of evidence-based resources. Marty also highlights her involvement in the Michael J. Fox Foundation's Parkinson's Progression Markers Initiative (PPMI) research study and offers perspective on emerging advances and potential disease-modifying therapies that may shape the future of Parkinson's care. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen/
Internationally-renowned as a nutrition expert, physician, and founder of NutritionFacts.org, Dr. Michael Greger examines the fifteen diseases that are the leading causes of death in America—heart disease, various cancers, Alzheimer's, diabetes, Parkinson's, and more—and explains how nutritional and lifestyle interventions can often surpass the modern medical approach, freeing us to live longer, healthier lives.Doctors are good at treating acute illnesses, but bad at preventing chronic disease. The fifteen diseases that lead to the most deaths in America claim the lives of 1.6 million annually. This doesn't have to be the case. For the most part, these diseases and illnesses are preventable. In this revised and updated edition of the bestselling classic, Dr. Michael Greger shares groundbreaking scientific discoveries in nutrition and longevity. With updates from all of the most recent studies, HOW NOT TO DIE is a guide to the methods proven to keep the reaper off our backs, detailing the foods we should eat and the lifestyle changes we can make to live longer.Full of practical, actionable advice and surprising, cutting-edge nutritional science, these doctor's orders offer the best chance for living healthy well-beyond our expiration dates.Become a supporter of this podcast: https://www.spreaker.com/podcast/arroe-collins-like-it-s-live--4113802/support.
Known for his record-breaking run as Deadpool in Marvel films, Ryan Reynolds is an award-winning actor and producer whose career spans hits like Deadpool & Wolverine, Free Guy, and The Proposal. In this conversation from September 2024, Reynolds joins Willie Geist to discuss the massive global success of the Deadpool franchise, his wide-ranging career, and how he balances work with life as a father of four. Plus, he opens up about his late father's long battle with Parkinson's disease and the impact it had on his family. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Molecular biologist Judith Frydman studies the nuances of protein folding and how defects in the process lead to neurodegenerative diseases. Her team studies protein folding in human cells and in model organisms, like yeast and worms, to understand the molecular events that precipitate harmful protein defects in humans. In one example, Frydman's team explored how aging affects the creation and the quality of proteins in the brain, leading to cognitive problems. She is now looking to develop therapies – someday perhaps leading to cures – to debilitating diseases such as Alzheimer's, Parkinson's, Huntington's, ALS, and others. The power of science gives her true hope in these important pursuits, Frydman tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Judith FrydmanConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Judith Frydman, a professor of biology and genetics at Stanford University.(00:04:00) Linking Protein Folding to AgingHow aging disrupts protein-folding machinery across many organisms.(00:07:16) Universal Aging PatternsThe similar age-related protein-folding defects found across organisms(00:09:27) Studying Killifish AgeingResearch on the African killifish as a rapid-aging model organism.(00:13:05) Ribosome Function DeclinesHow aging causes ribosomes to stall and collide, creating faulty proteins.(00:15:31) Aging Across SpeciesThe potential factors causing alternate aging rates in different species.(20:11) What Fails Inside Aging CellsThe cellular components that are leading to bad protein creation.(00:24:04) Therapeutic ApproachesPotential interventions to combat cellular and neurological degeneration.(00:25:12) Gene vs. Small-Molecule TreatmentsHow some interventions may be better suited for certain diseases.(00:27:47) Ribosome Drug PotentialWhy ribosomes and translation factors are viable drug targets.(00:28:56) Next Steps in Aging ResearchUsing human skin fibroblasts to study human aging mechanisms.(00:31:46) Future In a MinuteRapid-fire Q&A: scientific progress, young researchers, and archeology.(00:33:54) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "Mood, Behavior, and Quality of Life in Parkinson Disease," Sneha Mantri, MD, MS, Chief Medical Officer at the Parkinson's Foundation, discusses how mood and behavioral symptoms shape the lived experience of people with Parkinson disease across the disease course. Mantri, a practicing movement disorders specialist with extensive training and experience, explains why depression and anxiety often precede motor symptoms, how these issues evolve with cognitive change, and why they remain key drivers of quality of life. Mantri reviews commonly used screening tools – including the PHQ-2/9, Geriatric Depression Scale, GAD-7, and emerging measures like the HOPE questionnaire – emphasizing their role in opening deeper clinical conversations. She also highlights Parkinson's Foundation initiatives that support both clinicians and patients, from PD Health at Home programming to team-based care models. The conversation concludes with ongoing challenges, including cultural barriers to mental health care, access limitations, and the continued need for true mental health parity in Parkinson disease management. Looking for more Movement disorder discussion? Check out the NeurologyLive® Movement disorder clinical focus page. Episode Breakdown: 1:10 – How mood and behavior symptoms shape Parkinson disease quality of life 5:30 – How conversations about mental health in Parkinson disease have evolved 9:25 – Screening tools and practical assessment strategies for mood and anxiety 13:40 – Neurology News Minute 15:50 – Foundation and community initiatives supporting mood and behavior care 19:50 – Remaining gaps, cultural barriers, and mental health parity challenges The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: CTAD Presentation Lays Insights Into Disappointing Phase 3 EVOKE Trial of GLP-1 Semaglutide in Alzheimer Disease Gene Therapy ETX101 Demonstrates Significant Effects on Seizure Reduction, Neurodevelopmental Outcomes in POLARIS Phase 1/2 Program FDA Accepts NDA for Low-Sodium Oxybate TRN-257 in Narcolepsy and Idiopathic Hypersomnia Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.
Restless leg syndrome (RLS) isn't just a sleep problem — it's a neurological signal that your brain's dopamine and iron systems are under stress, and addressing it early helps protect long-term brain health A JAMA Network Open study found that people with RLS were significantly more likely to develop Parkinson's disease than those without it RLS patients who received treatment had four times fewer Parkinson's diagnoses than untreated individuals, suggesting that managing RLS symptoms supports neurological resilience Iron levels, poor sleep quality, and disrupted waste clearance in the brain all appear to link RLS and Parkinson's, underscoring the importance of restoring iron balance and improving sleep hygiene By optimizing dopamine naturally, maintaining healthy iron levels, getting quality sleep, and staying physically active during the day, you can calm restless legs now and strengthen your brain against degeneration later
Patrick brings gratitude to the forefront, reflecting on everyday comforts like hot showers, electricity, and medicine that past generations never imagined, and urging listeners to reconnect with a spirit of thankfulness. He guides callers through raw, honest conversations about faith, suffering, prayer, and how even the smallest actions can bring hope, always tying their stories back to practical acts of love, humility, and remembering God’s mercy. In each exchange, Patrick reveals how a grateful heart transforms how he faces hardship, community, and life’s simplest joys. What are you thankful for? (00:20) Becky - I have Parkinson's disease and am meeting with a Deacon. He and a friend are doing a deliverance prayer over me. Is this ok? (09:54) Pat - Gratefulness is a magnet for miracles. Being grateful opens your heart to God. I have found this to be very meaningful. (15:08) Christine - I agree with what you are saying about gratitude. It is important to remember history and always remember it. (17:15) Pam - I wanted to thank Patrick. You talked about St. Pio. A miracle happened to me. (21:41) Carlos - I find that serving others can help you overcome this feeling of struggling to love God. When you help others, you will come to God. (27:09) Tom - Why in the Middle Ages did God allow the Church to become so corrupt? (31:29) Jacquelynn (email) – Can I bless my son with Holy Water? (38:35) Stephanie - My 3-month-old son was sick, and my husband stayed home with him and my daughter. Was it a sin of omission not to take her? Also, I feel guilty for not helping the poor more. (43:38) Originally aired on 11/17/25
What if protein degradation could address neurodegenerative diseases, not just cancer? In this episode, Dr. Angela Cacace, CSO at Arvinas, speaks with Dr. Talar Hopyan, Global Head of CST at Syneos Health, about how the company is advancing a degrader targeting LRRK2 in Parkinson's disease and why early-stage signals in healthy volunteers are raising new possibilities for CNS care. They discuss how Arvinas is engineering blood-brain barrier-penetrant molecules, the translational challenges in neurodegeneration and what's required to move from platform to patient. What you'll learn: How Arvinas is expanding targeted protein degradation into neurology Why LRRK2 degradation is a promising approach for Parkinson's disease What it takes to translate platform innovation into measurable clinical outcomes The views expressed in this podcast belong solely to the speakers and do not represent those of their organization. If you want access to more future-focused, actionable insights to help biopharmaceutical companies better execute and succeed in a constantly evolving environment, visit the Syneos Health Insights Hub. The perspectives you'll find there are driven by dynamic research and crafted by subject matter experts focused on real answers to help guide decision-making and investment. You can find it all at https://www.syneoshealth.com/insights-hub. Like what you're hearing? Be sure to rate and review us! We want to hear from you! If there's a topic you'd like us to cover on a future episode, contact us at podcast@syneoshealth.com.
In this episode, I sit down with my friend Shawn Johnson. He is the lead pastor of Red Rocks Church, an author, and someone God has used to impact thousands. And he is the coolest! Shawn shares openly about being diagnosed with Parkinson's, the battle with depression that followed, and what it looks like to keep getting back up when life knocks you down. We talk about choosing joy on purpose, why fun actually matters in your faith, and the hope that will hold steady even on the hardest days. If you've ever felt like giving up, or you're trying to keep going when things feel heavier than you expected, Shawn's story will speak straight to your soul. It's honest. It's encouraging. And it's a reminder that God does some of His best work in the fire. Thanks to our amazing partners on this episode: International Justice Mission is a global nonprofit working to end slavery and violence around the world, taking special care of survivors from the moment they're rescued all the way through their healing and restoration. To learn more and support their mission, visit ijm.org Vern Eide Motorcars is a growing employee-owned company that offers sales, service, and financing of automotive, motorcycle, and power sports lines, including Acura, Ford, Chevy, GMC, Honda, Hyundai and Mitsubishi brands. Whether you live locally or across the country, visit https://www.verneide.com/ Subscribe to The Conversation on YouTube and watch the full interview with Shawn: youtube.com/@adamaweber Sign up for The Crew: https://www.adamweber.com/thecrew
????️ Guest: Phil McKelvy, DPT???? Topics: Parkinson's care without neuro certs, RTM implementation, digital health, and balancing clinical work with creative PT projects.What you'll learn:Why intensity matters more than certifications in Parkinson's careFree tools to treat movement disorders without overwhelming your practiceThe truth about RTM: what it is, how to do it, and why it's here to stayHow to think differently about burnout, energy, and filling your cup in PTWhy APTA isn't just about CEUs — it's about connection???? Resources Mentioned:Rogue Physical Therapy YouTubePower for Parkinson'sMatt Jurek on RTMPrompt EMR, Orva HealthOne More Wave - Adaptive Surf Therapy???? Phil's Contact:???? philmckelvey@gmail.comLinkedIn: Philip McKelveyInstagram: @philmckelvey.dpt
Occupational therapist and aging-in-place expert Carol Chiang joins us to discuss her new book, Age in Place or Find a New Space. Carol explains why meaningful interactions—not just safety—belong at the center of planning for life with Parkinson's, and how "the choices you make today become the consequences you live with tomorrow." In this podcast episode, Carol discusses the importance of early-stage steps like decluttering and fall-prevention basics, practical visual cueing for freezing, how to break home updates into manageable pieces, and honest caregiver conversations. Carol also shares how to think about modifying a home versus considering a move, and why planning early protects both independence and connection. A grounded, hopeful conversation about creating a home that supports who you are and how you want to live. Learn more about Carol and her work, and find her book at: www.EvolvingHomes.com Explore the OT-curated home-modification resource she mentioned: Ask Samie: https://www.asksamie.com/ Sign up for updates on webinars, events, and resources for the Parkinson's community: https://dpf.org/newsletter-signup Learn more about the Davis Phinney Foundation for Parkinsons's: https://dpf.org GUEST BIO Carol Chiang is an Occupational Therapist and founder of Evolving Homes®, specializing in aging-in-place, age tech, and smart home solutions. With 25 years of experience, she helps individuals and families decide whether to "Age in Place" or "Find a New Space®," and supports them through the home changes required at each stage of Parkinson's. A Certified Parkinson's Wellness Recovery therapist and former Olympic-caliber athlete, Carol teaches the importance of planning ahead, using exercise as medicine, and building habits that protect long-term independence. She consults with organizations, startups, and universities worldwide, and has contributed to AARP, the Davis Phinney Foundation, the National Kitchen & Bath Association, and international aging conferences.
For years now, scientists have shown that daily exposure to bright light therapy, which simulates the intensity of outdoor light, can be beneficial for people with insomnia and other sleep disorders, Seasonal Affective Disorder or other forms of depression. But what if bright light therapy can help people recover from concussions or other traumatic brain injuries? And what if it can also lower the risk of neurodegenerative diseases like Parkinson’s or Alzheimer’s, which people with TBIs are at higher risk for? Scientists at Oregon Health & Science University were recently awarded a $4 million grant from the U.S. Department of Defense to explore these questions and possibly unlock more secrets about sleep and its effect on health. The OHSU researchers will recruit nearly 120 military veterans who have suffered a TBI. The participants will be given a light box to use at home for one hour each morning for four weeks. Blood samples will be drawn from participants to look for changes in markers that signal inflammation in the brain and changes in oxygen uptake in brain cells. MRI scans of participants’ brains will also help reveal if the bright light therapy has improved activity of the glymphatic system - a relatively recent discovery about the role of sleep in reducing toxins that can lead to neurodegenerative diseases like Alzheimer’s. Joining us for more details of the study and to share new insights about sleep science is Jonathan Elliott, assistant professor of neurology and co-director of the Sleep & Health Applied Research Program at OHSU.
Caregiving is a sacred gift. Caring for someone who is chronically or terminally ill requires patience, understanding, and selflessness. Most caregivers are not professional healthcare workers; rather, they are loving family members who dedicate their lives to improving the well-being of their loved ones.Caregiving often presents significant challenges and in this episode, Robin's husband, Tom, is here to talk about them. His mother, like many individuals who are ill, required round-the-clock care. For Tom and other caregivers who work outside the home, this situation leads to difficult decisions: choose between paying for private care or providing the care themselves. There are no easy solutions to this dilemma, as Tom explains. When we care for one of God's children, we are truly doing the Lord's work. Most who have been in the caregiving role, including Tom after three months at his mother's bedside, deem the experience a blessing beyond measure. If you aren't a caregiver but know someone who is, consider offering support, respite, or, at the very least, prayers and encouragement. Also, send them this episode so they know they are not alone.Special Guest: Tom MayTom and his sister committed to keeping their mother at home as she battled Parkinson's Disease and cancer. This commitment didn't come easy or without challenges. He joins us today to discuss them. Tom is the husband of Robin, and together they have two children and one granddaughter. Show NotesThe Caregiving Crisis No One is Talking About https://www.mariashriversundaypaper.com/the-caregiving-crisis-ai-jen-poo/?utm_source=SailThru&utm_medium=email&utm_campaign=Fall%20Issue%20No.%207%20November%209%2C%202025&utm_term=Sunday%20PaperCaregiver Bill of Rightshttps://www.caregiver.org/resource/caregivers-bill-rights/Celebrating National Family Caregivers Month with BLS Datahttps://www.bls.gov/blog/2023/celebrating-national-family-caregivers-month-with-bls-data.htmThe Overwhelming Financial Toll of Family Caregiving https://www.aarp.org/caregiving/financial-legal/financial-impact-caregiving/Family and Medical Leave Acthttps://www.dol.gov/agencies/whd/fmla‘Tis the Seasonhttps://denisebickel.com//tis-the-season
Parkinson's disease, a progressive movement disorder whose hallmark is damage to the dopamine-producing neurons in the brain, afflicts almost 12 million people worldwide. And the number of new cases is growing quickly. For roughly 13% of patients, genetics plays a key role. For many others, the underlying cause of the disease might be more mundane and insidious: environmental toxins — via the air we breathe, the water we drink, the food we eat and the chemicals with which we regularly come in contact. Neurologist Dr Michael Okun, co-author of The Parkinson's Plan, joins CNN Chief Medical Correspondent Dr Sanjay Gupta to discuss where we stand today in our understanding of this disease, and the “PLAN” moving forward. This episode was produced by Andrea Kane Medical Writer: Andrea KaneShowrunner: Amanda SealySenior Producer: Dan BloomTechnical Director: Dan Dzula Executive Producer: Steve Lickteig Learn more about your ad choices. Visit podcastchoices.com/adchoices
Dr. Glen Jeffery, PhD, is a professor of neuroscience at University College London and a leading expert on how different colors (wavelengths) of light impact cellular, organ and overall health. He explains that long-wavelength light (red, near-infrared and infrared) can enter the body and brain to enhance mitochondrial function and thereby improve metabolism, eyesight, blood glucose regulation, mood, hormones and more. We also discuss how short-wavelength light from LED bulbs can impair mitochondrial health and why balanced, full-spectrum light is essential for health. Dr. Jeffery shares simple yet powerful ways to use natural and artificial light sources to enhance your metabolic function, eyesight and longevity. Sponsors AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman Joovv: https://joovv.com/huberman Rorra: https://rorra.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00 Glen Jeffery 03:12 Light, Ultraviolet (UV), Visible & Infrared (IR) Light 06:25 Light's Impact on the Body & Light, Sunburn, Cataracts 09:55 UV Light, All-Cause Mortality, Skin Cancer 14:55 Sponsors: Wealthfront & Joovv 17:58 Light Impacts Mitochondria Function & Structure, Long-Wavelength Light (Red/IR), Nano Water 25:00 Long-Wavelength Light Passes Through Clothing & Body; Tissue Scattering 30:08 Long-Wavelength Light & Blood Glucose; Mitochondria 36:19 Red Light, Parkinson's Disease, Cell Death; Eye Rods & Aging; Mitochondria Community 42:46 Red/IR Light, Skull & Brain; Safe Non-Ionizing Radiation 48:22 Sponsors: AG1 & Rorra 51:04 Offsetting Retinal Aging, Improve Vision & Long-Wavelength Light 59:28 Tool: Long-Wavelength Light & Preserve Retinal Mitochondria; Sunlight 1:03:50 Mitochondrial Theory of Aging, Circadian Rhythm & Mitochondria 1:07:57 Tool: Improve Vision with Long-Wavelength Light 1:10:44 Macular Degeneration, Rescuing Vision, Early Intervention 1:13:59 Light Effects at Local vs Distant Tissues, Immune System, Body Communication 1:19:09 Sponsor: Function 1:20:56 Short-Wavelength Light, LED Light, Mitochondria & Serious Health Detriments 1:28:39 Lifespan, LED Lights; Sunlight & Balanced Wavelengths; "Sunlike" Marketing 1:34:45 Fires, Incandescent Lights vs LED Lights, Lasers; Long-Wavelength Devices 1:39:07 Incandescent & Halogen Bulbs, Mitochondria & Built Environments 1:45:19 Windows, Light & Office Work; Screens, Kids & Myopia; Tools: Plants; Lighting 1:55:56 Bring the Outdoors Indoors 2:00:35 Tool: Candlelight; Dim Halogen Lamps 2:05:06 Mitochondrial Diseases, Children & Long-Wavelength Light; Light Bulbs 2:11:53 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC. Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices