Podcasts about Muth

König Max II. war 1858 fünf Wochen in Bayern unterwegs, um die schönsten Winkel seines Königreichs zu bestaunen. Die BR Heimat-Kräuterexpertin Astrid Süßmuth zeichnet im Ratsch mit Andreas Estner die einstige Reiseroute nach.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

En este episodio del Podcast de Nutrición de Fit Generation hablamos con el nutricionista Muthanna Abusaada, más conocido como Nutrymuth en redes, sobre cómo ganar músculo y definir de forma inteligente, sin destrozar el rendimiento, la salud ni la relación con la comida. Analizamos el papel de cada macronutriente, cómo hacer una buena etapa de volumen y una de definición, y qué errores hacen que tanta gente se estanque. Todo ello con un enfoque basado en ciencia y pensado para mejorar físico, salud y rendimiento. ➡️ Instagram de Muth: https://www.instagram.com/nutrymuth/

Auf den ersten Blick schaut eine Moor-Fläche eintönig aus, doch wer genau hinschaut, entdeckt eine Vielzahl kleiner Blüten und zahlreiche Kräuter. Die BR Heimat-Kräuterexpertin Astrid Süßmuth streift mit Andreas Estner durchs Moor.

Lucas County Children Services are doing a community survey and they want your input. You can go directly to lucaskids.net to participate

Wildkräutersammeln ist beliebt. Gerade im Frühling locken das satte Grün und bunte Blüten. Die BR Heimat-Kräuterexpertin Astrid Süßmuth stellt bei Andreas Estner ihre Lieblinge vor.

The Kentucky Supreme Court blocks the General Assembly from continuing its impeachment proceedings against a Fayette County circuit judge, Kentucky political leaders react to the firing of Attorney General Pam Bondi, a look back at one of the most destructive spring weather events in Kentucky's history, and meet the only ATF accelerant detection K-9 in the state of Kentucky.

The Forest and the Trees 4/6/26: Treehouse's Erica Couster (CEO) & Lynn Muth (community member) & Tara Brewster GSB VP & Dir of Philanthropy: foster care, community & the Runway 5K. Cammie McGovern: “The last Letters of Sally and Walter”— love in a retirement community. MHC Visiting Fellow in Creative Writing Mariah Rigg: “Extinction Capital of the World.” Northampton Mayor GL Sciarra: the school budget & Picture Main Street.

Die Verwendung von Pflanzen nicht nur als Nahrungs- oder Heilmittel, sondern auch als Haushaltsgeräte, Werkzeuge, und Kleidung begleitet den Menschen seit Urzeiten. Die BR Heimat-Kräuterexpertin Astrid Süßmuth unterhält sich in "Habe die Ehre!" mit Andreas Estner über besonderes Pflanzenwissen, das schon der Gletschermann Ötzi hatte.

This week on American Family Farmer Show, host Doug Stephan welcomes ecologist and biology professor Norris Muth for an insightful conversation about the health of our forests, farms, and ecosystems.A professor at Juniata College in Pennsylvania, Muth specializes in conservation biology, plant ecology, and the growing challenges posed by invasive species. His research through the Muth Ecology Lab focuses on how invasive plants and insects disrupt native ecosystems—and what can be done to restore balance.Doug and Norris discuss the importance of native plants in both rural and urban landscapes, the ecological impact of invasive species like Tree-of-Heaven, and how threats such as the Hemlock Woolly Adelgid are changing forest and stream ecosystems. They also explore how farmers, landowners, and communities can play an active role in protecting biodiversity and supporting healthier environments.Drawing from his experiences as a researcher, educator, and former National Park Service ranger, Muth shares practical insights on conservation, ecosystem management, and why understanding the natural systems around us is critical for the future of agriculture and rural America.Tune in for a thoughtful discussion about the connection between farming, forests, and the natural world—and how better stewardship today can help preserve healthy landscapes for generations to come. Website: AmericanFamilyFarmerShow.com Social Media: @GoodDayNetworks

Bryan Anthony Davis discusses rumors before the start of free agency and more on his solo show, BAD Language. Steel Curtain Network is courtesy of the Fans First Sports Network. Learn more about your ad choices. Visit megaphone.fm/adchoices

Click here to share your favorite car, car story or any automotive trivia!“Every car tells a story, and those stories reveal exactly who we are.” In this episode, Doug and Dave welcome professional corporate and lifestyle photographer Marla Aufmuth into the virtual garage. While Marla has documented landmark cultural events for brands like Nike and TED Talks, her heart belongs to the air-cooled Volkswagen community.

Nyheter och fördjupning från Sverige och världen. Lyssna på alla avsnitt i Sveriges Radios app.

Abu Sufyaan Ibn Harb رضي الله عنه (S8) The Messenger ﷺ returns to Makkah from Ta'if. al-Muth'im Ibn Adee offers protection to the Messenger ﷺ whilst he ﷺ performs Tawaf. The Messenger ﷺ said: “If Muth'im asked me to release the prisoners of Badr, I would have done so”. Never forget when someone does good for you. The build up to Badr: The Quraysh had taken the belongings of the believers رضي الله عنهم. A large caravan with ~1,000 camels lead by Abu Sufyaan رضي الله عنه was coming from Syria. The intention of the Muslims رضي الله عنهم was go to for the caravan, not for battle.

Der Fasching ist nicht nur eine ausgelassene Zeit des Feierns, sondern auch eine Zeit vieler alter Bräuche des Winterverscheuchens. Die BR Heimat-Kräuterexpertin Astrid Süßmuth ratscht mit Moderator Anderas Estner über das närrische Treiben in der Pflanzenwelt - ob als Symbolpflanze, Verkleidung, kuli-narrische Verlockung oder Faschingsattribut.

Heckmann, Dirk-Oliver www.deutschlandfunk.de, Informationen am Morgen

Jonell Muth, the kitchen manager at Haven of Rest, details the mission's critical response to a severe Ohio winter storm by providing warm, hearty meals to those in need. With the help of dedicated volunteers, the kitchen prepares roughly 150 meals for breakfast and lunch and over 250 for dinner, often scaling up to 300 during peak blizzard conditions to ensure no guest is turned away hungry. Jonell guides her team to treat every guest like family, eschewing cold sandwiches for nutrient-dense options like soups and stews made with massive quantities of ingredients, such as 100 pounds of chicken and 80 pounds of tortellini. Beyond the kitchen, the mission operated as an "all hands on deck" environment where staff and guests worked together to clear snow and maintain a life-saving warm shelter. To continue this 365-day ministry, the mission is currently requesting donations of canned goods, coffee, and desserts, and invites new volunteers to reach out to their coordinator, Christina at 330-535-1563.

Dr. Deb Muth 0:03There’s a quiet shift happening in healthcare right now, and most doctors aren’t talking about it yet. People aren’t chasing diagnoses anymore. They’re exhausted by them. I see it every single day in my clinic. People who come in with stacks of paperwork, portals full of results, and a list of diagnoses longer than their grocery receipt, yet they’re still not living their lives. And they’ll say to me, Dr. Deb, I don’t want another label. Dr. Deb Muth 0:32 I just want my life back. If you’ve ever been told this is just how your body is, if you’ve been diagnosed, rediagnosed, and then dismissed, if you’ve been handed labels but never handed a roadmap, today’s episode is for you. Because we are officially entering what I call the post diagnosis era and it’s changing everything about how healing actually happens. So grab your cup of coffee or tea and let’s settle in to let’s talk wellness. Now, before we dive in, we need to take a quick pause to thank today’s sponsor. And when we come back, we’re going to talk about why diagnoses are no longer the most important thing about you. Dr. Deb Muth 1:17Did you know sweating can literally heal your cells? And infrared saunas don’t just relax you, they detox your body, balance hormones, and boost mitochondrial energy. I’m obsessed with my health tech sauna, and right now you can save $500 with my code at healthtechhealth.com Dr. Muth req 25 so here’s some truth for me. Dr. Deb Muth 0:47It was three years ago Christmas that I received my Ms. Diagnosis. And I remember it very clearly. It was the day before, two days before Christmas Eve, that I got the call and I heard the words, you have white matter brain disease. That’s consistent with Ms. And I immediately stopped in my tracks and thought, okay, well, this is just the way it is. We’re gonna fight this. We’re gonna figure this out. And it led me down a deeper path of healing and spirituality and emotional growth. And there were some really difficult days ahead for me because I remember thinking, what am I gonna do? How am I gonna practice what’s going to happen in my life? And every year at this time, I reflect back to that day that I got the call that really changed my life. And not for the worse, but for the better. It changed the way I was thinking about life. Dr. Deb Muth 3:01It changed the way I was complaining about things being ungrateful for all the amazing things that I have in my life. Not intentionally, but just living the American life. Right. Dr. Deb Muth 3:14And striving for more and wanting more and chasing more and doing more, and never really having the opportunity to just be present and just really think about life and enjoy what the Lord has given us and enjoy what’s around me, the people in my life, the family that I have, the amazing practice that I have, and the amazing people I get to work with and change lives with. And it really changed me for the better. And I’ve watched diagnoses like this change people for the worse and for them to sink deep into a depression and give up and. And live to their label instead of living to their potential. And that’s why I think this episode is so important for us, because we all have a choice in life. When we get dealt something kind of difficult, we can let it consume us and let it take every ounce of life from us, or we can allow it to become the fuel that makes us better, makes us contribute to life maybe differently, but in a better way. So, you know, I know that this idea of letting diagnoses lose their power can be really uncomfortable for some people, because there’s people that are waiting for that diagnosis. I’m in some. Some social media groups, and I’m listening and reading to people who are saying, I’m so angry I didn’t get the Ms. Diagnosis today. I’m so angry I didn’t get the Lyme diagnosis today. I’m so upset that they can’t find anything wrong with me. And I understand. Dr. Deb Muth 5:20I know the feeling of wanting to put a name to what you’re feeling so that you have validation and you have power around this diagnosis, and you can prove to people that what you’re feeling is not in your head. I get all of that. But for many people, the original diagnosis is meant to help guide treatment in the conventional sense. It’s a created, shared language that we have, and it brings clarity. But for many people, you give that label and that name so much power and so much control over your life and who you are and what you’re being. And that’s not what the label is meant for. Somewhere along the line, medicine started confusing naming with healing. And today, we have more diagnoses than ever. We have more testing than ever. We have so many thousands of specialists, and yet people are sicker. They’re more inflamed, they’re more exhausted, they’re more confused than ever. And that’s not just a coincidence. That is how the system is meant to work. It’s meant to confuse you. Dr. Deb Muth 6:44It’s meant to keep you dependent on it. It’s meant to. Meant to keep you on medical management for the rest of your life. And by doing that, we enrich the pharmaceutical companies to the point where their whole role is to continue to create drugs that you need to be on for the rest of your life. And the hard truth about all of this that I’ve seen in my practice is for many patients, the diagnosis really becomes their identity. They own it, they gravitate to it. It’s who they are. It also becomes their prison because they only live confined inside the diagnosis. I can’t do this because I can’t do that, because if I do this, this will happen, because I have. They’ve capped their ceiling of life based on a couple of words that somebody gave them at a point in their life when they were so low and potentially so desperate that they needed that name to identify themselves and what was going on. And instead of asking, why is this happening? Dr. Deb Muth 8:05Why are these symptoms happening? What’s causing these symptoms? They’re told, this is what you have, and this is what you’re going to have to live with. And instead of restoring function, these people become managed. Like I said, they’re managed with drugs. They’re managed inside the system. And instead of healing, they’re monitored with this blood test and that blood test and this MRI and that mri. Instead of providing hope, they’re handed a lifelong prescription with expectations that do nothing but decline. So you walk out of that room with this expectation that your life is never going to be the same, that your function is going to decline, your neurological disease is going to take over eventually, you’re going to be put in a home, you’re going to lose everything you have because you’re not going to be able to afford the care that you need. And that’s the expectations of our healthcare system today. When you’re labeled with a chronic illness diagnosis, and for a woman, especially women, this is magnified because their symptoms are told to them as. It’s stress, it’s hormones, it’s anxiety, it’s aging, it’s motherhood, and then, of course, it’s perimenopause. Like that is some major traumatic thing that should disrupt your entire life. Yet it shouldn’t, and it does, and it doesn’t have to. And of course, my favorite is always, but your labs are normal. We don’t know what’s wrong with you. It must just be in your head. Dr. Deb Muth 9:53And this is why women are done being dismissed, why this shift is happening now that we are empowering women to take back Their lives, take back who they are and take back how they’re being treated in the healthcare system. And it is one of the most important things that we can do right now is to give women their power back so that they can stand strong in who they are and in their intuition and fight and say, no, this is not happening to me right now. I am not accepting this label. I’m not accepting this diagnosis. I will fight, I will find answers, and I will do what I need to do to be the woman that I want to be. So why is this conversation exploding right now? Well, there’s actually three big reasons, and first and foremost, it’s over. Diagnosis, burnout. People are collecting diagnoses without solutions. Autoimmune labels, syndromes, vague neurological names, but no one’s connecting the dots. Dr. Deb Muth 11:02You see, when you start to stack these labels on top of each other, one after the next after the next, you know, it’s celiac disease, it’s Hashimoto’s, it’s fibromyalgia, it’s autoimmune. You know, rheumatoid arthritis. It’s. Whatever it is, it’s long haul Covid. These days, no one is putting these connections together to say, why are you developing so many diseases that are so similar in nature, ones that just kind of domino after each other? Nobody’s looking at your immune system. Nobody’s measuring it, Nobody’s telling you how well it’s working. No one’s supporting it. They’re just throwing these biological drugs at you. And if there’s an autoimmune disease and sending you on your way and saying, this is what you have to look forward to for the rest of your life. But don’t worry, these side effects are rare, including cancer. It does not make sense to me that we are not looking at the root cause for all of these crazy diagnoses that we are labeling people with today. And I am guilty of it myself, because within the system that we work, we have to label something in order for you to receive the care that you need, for your insurance, to pay for the treatment, for the tests, for the visits. There has to be a label. And that’s what we call an ICD10 code. And if we don’t have the appropriate label, none of what we’re recommending gets covered for you. And that’s the label game began. The second thing is long haul Covid. And post viral illnesses. Dr. Deb Muth 12:47Millions of people were told, we don’t know why, and then we sent them home to figure it out by themselves. We don’t know why your immune system is failing, we don’t know why you’re having these clotting issues that are happening. But don’t worry, these clotting issues really are not that severe. They’re mild in nature. You’ll never have to worry about it. And we’re not going to treat it even though it’s four times the level that’s normal, because we’re going to wait until it’s 10 times the level of normal to even worry about it at this point. Dr. Deb Muth 13:19And it will take us 25 to 30 years before we understand any of the risks and barriers that have happened from these post viral illnesses that have occurred in our environment and the ones that are in the future to come. Because it takes time for us to study things, it takes time for us to figure it out, takes time for us to train the practitioners, and it takes time for us to accept something different than we thought was reality. And that is the problem that we have today with these post viral illnesses that are long acting, that are retriggering new viruses, retriggering old illnesses like Lyme, reactivating things like Epstein Barr virus. It will take decades before this becomes mainstream. And right now it’s fringe medicine and it’s not realistic. And those of us that are speaking about it are chastised and gone after, but by our medical communities and we are told that we are the crazy ones. And that is how medicine has always been. Way in the beginning, and I forget the doctor’s name, who started just observing that when medical students worked on cadavers and then came into the labor and delivery ward and delivered babies, these women were getting sick with infections and they were dying. And he said, what if we just washed our hands between the cadaver and the delivery? Would we save lives? And he did a small study and he was right. And over time he was made fun of and he was put into insane asylums and he was locked away. And now today we would never think of entering a room and working on a patient without washing our hands beforehand. But that took 30 years for that one concept of washing hands to be adopted. And it destroyed one man’s life because he simply asked the question, what if it’s a crazy society that we live in, It’s a crazy outlook that we have on medicine and asking questions. And sometimes I wonder, is it truly science or is it politically driven? And I think the answer is it’s both. And the third thing that we have is technology. And technology is outpacing wisdom by far. Hands down, AI, advanced labs and imaging can identify everything. Now using AI, but without context, it creates a fear. Dr. Deb Muth 16:08And instead of clarity, without context, using AI to interpret labs makes absolutely no sense. Without context and understanding and us actually training this LLM model, the AI doesn’t really know what it, what it means. And someday it will, I’m sure, but right now it doesn’t. So as everyone is taking to AI to treat themselves and create a protocol and diagnose themselves and understand their labs and know that it is without context that you are doing this, and research is wonderful, but without having somebody truly understand you and the art of healing and the art of medicine, this is going to get lost and you will not have the information that you truly need simply by using chat GPT. Now I’ve created my own version called Venari and I hope that this will be much better because it will have context. It will have 15,000 protocols that I have used for the last 25 years. It will have lots of research. It has all of the research databases that we can connect to. It has training that I have given it using my brain and how I see a client every single day in practice. So when you’re using our Venari app, you will be able to have that context. You will be able to have that pushback and that voice. And not only that, you will have the option then to work alongside someone to help you identify that context that you’re looking for. Does this make sense? Dr. Deb Muth 17:53I’ve seen this a lot in the peptide world, where in these Facebook groups, people are talking about the peptide stacks that they’re using and they’re telling people that it’s okay to use any peptide you want because they’re just small chain branch amino acids. And that can’t be farther from the truth because there are some peptides you would not want to use because they can stimulate the growth of cells. And if you have cancer or if you have a history of this, there are some peptides that we need to avoid. And unfortunately, AI doesn’t understand that yet and doesn’t know that yet. And it’s just creating stacks. And people are creating stacks without understanding what they’re doing. And I watched my best friend do this as she was learning peptides and she had cancer and it created an aggressive sarcoma. And I believe the peptides had a lot to do with that because it stimulated the growth of the cells. And it wasn’t until after she had passed away that we found this journal of hers that she was studying peptides and recognized that this could have contributed to her advanced cancer. And if you don’t have that context and you’re using AI to create these stacks for you, you can put yourself in harm’s way. And so AI technology, I think, is going to be fantastic in a lot of ways. It’s going to have its downfalls. And you’re going to need an expert when you’re using AI. You’re not going to just be able to treat yourself with this. You know, understanding that more data doesn’t always equal healing, and more data can be helpful. But again, you have to understand how to put those pieces together, how to ask the right question questions. And for that, you need somebody who has seen thousands and thousands of cases to find the missing pieces for you. Because AI is not going to do that unless it’s been trained to do that. Vanari has been trained to do that. Dr. Deb Muth 20:01It’s been trained to push back and look at lime and mold and toxins and chemicals and metals and all of those things. But there is no other AI bot out there, LLM that has been trained to do that using clinical data that I use every single day in my practice. And people are finally realizing that, you know, they’re understanding that although this world of AI and technology is amazing, it has its limitations, just like practitioners have their limitations. We don’t know everything. We are not perfect. We are human. And humans make errors and we miss things. With or without technology, we miss things. And part of it is because we just don’t know what we don’t know yet. And sometimes it’s because we have our blinders on, and sometimes it’s just simply because we don’t have the information today that we’re going to have five years from now. And here’s what I teach instead. I teach the seenet last. And that’s what we built it on. Restore and root. Rise and restore. Sorry, that is my methodology. And it’s in the scene at last book. And it starts with healing. It starts with asking better questions. So instead of asking, what do you have? We want to ask, what has your body been exposed to? What symptoms are underperforming? What’s driving the inflammation for you? When you have joint pain and you have muscle pain and you have achiness, that is not normal. Dr. Deb Muth 21:38I don’t care if you’re 20 or you’re 80, it is not normal. And yes, I did say 80, because we are not supposed to have that kind of inflammation at 80. And why are we underperforming? Why is our Brain not working correctly? Why is our mood not working? Why can’t my body push up a hill? Why can’t I lift 10 pounds? What’s going on? Why can’t I recover from that activity? What’s interfering with my ability to repair and heal after I’ve done some things that I need to do? What’s keeping your nervous system stuck in this survival mode, in this fight or flight mode? Why can’t I get past that? Sometimes that answer is really simple and sometimes that answer, it is so hard and so complicated and it is so many things that are causing this body to be stuck. And sometimes it’s a six month fix, and sometimes it’s a six year fix and sometimes it’s decades long. And it is one of the most challenging things as a practitioner to get clients to understand and to be on the other side of the table and not get you that quick fix. It is extremely difficult for us as well when we are not seeing the results that we think we should see. We need to focus on function over diagnosis, root cause over labels. Dr. Deb Muth 23:09What is driving all this inflammation and certainly restoration over resignation. Do not resign to the fact that you have this life altering disease that is never going to change. Because if we find the root and we restore the body, you don’t have to live in that death sentence that you’ve been given of a diagnosis, whether it’s fibromyalgia, MS, Alzheimer’s disease, celiac disease, Hashimoto’s thyroiditis, it does not matter what that diagnosis is. We can change it, we can make it better, we can reduce the symptoms, we can improve your life. Maybe not in ways that you are absolutely looking for, maybe not in a perfect world, but we can change the trajectory of where your life is going. And it’s because you’re not an ICD9 code or an ICD10 code. You’re not a code, you’re not an MRI result, you’re not a lab result, you’re a human body asking support, not a name. And I say that with a little hesitation because so many people are looking for the name. So many people are angry that someone didn’t find the name. I have clients that come to me that are so angry that the conventional medicine system did not identify their Lyme disease, that they’re looking for someone to sue and there is no one to sue because they didn’t find it, because sometimes they just don’t know. You’re asking for conventional medicine, practitioner and system to provide for you a label that is not within their wheelhouse to do. Because the way they treat Lyme disease and the way an eyelads practitioner looks at Lyme disease and has. Has the ability to test differently are two very different things. Dr. Deb Muth 25:27You’re asking for a system to perform in a way that they are not trained and guided to do. Then you’re looking and asking for somebody to place blame for an illness that you have, that you have yet taken ownership for. And I know that sounds harsh, and I know there’s going to be a lot of people that are angry at me for saying that. But I sit in front of you as someone who had Lyme disease, who had mold mycotoxin illness, who had high viral titers, who had post Covid peripheral neuropathy, who had the diagnosis of ms, who has white matter brain disease, who treated all of it not in the conventional world, who has halted the white matter disease and regrew her brain by 1.5 standard deviations, which is unheard of in 18 months. So I can say this to you. There is no one to blame for your lack of diagnosis or your diagnosis. It is life. It is what happens to us. And you have a choice at the crossroad to either take the path of hatred and anger and bitterness and blame and never getting better a result of that, or you have the ability to take the path of curiosity and openness and willingness to change and willingness to walk down a path that is different than what the conventional medicine is telling you to do. And those are your choices and you get to make those choices. But what you don’t get to do is blame some someone else and try to destroy them for something that they are not able to do. That is not what we get to do in this life. Dr. Deb Muth 27:29It is not right and it is not fair. If someone has truly injured you, that’s different. That’s different. But this looking to blame somebody because they didn’t give you a label, Ridiculous in my opinion. And if you’re listening and thinking right now, I’ve been diagnosed, but I’m not better, I want you to hear this clearly. You are not broken. You are not crazy, and you are not done. Sometimes the most healing moment isn’t getting that diagnosis. It’s realizing that the diagnosis was never the whole story. And that’s where the real healing begins. When we look at the entire story, we look at your entire life from the beginning to where you are now and what has happened to get you there. And once we get that, then we can put you back together. Not in the old way, in a new way in an amazing way, in a way that you would cherish your life for every moment that you have of it. Good, bad and ugly. A diagnosis should not be the doorway. It’s not a dead end. It is just the beginning. Remember, you don’t need another diagnosis. You need your life back. And that’s what’s important. Dr. Deb Muth 29:19We are living in a moment where medicine is being forced to evolve not because systems want to, but because patients are demanding better. This post diagnosis era isn’t about rejecting science, it’s about using it wisely. It’s about restoring function, dignity and hope. And I hope that if this episode resonated with you, share it with someone who’s been labeled but not yet helped. Because sometimes the most powerful healing starts when someone finally feels seen. Thank you for being with me here today. If you haven’t already, make sure you subscribe and follow. Let’s talk Wellness now on YouTube, Spotify or wherever you’re listening and I’ll see you next time. Until then, keep asking better questions, trusting your body and remembering you are more than a diagnosis.The post Episode 254 – Beyond the Diagnosis: Healing in a Post-Diagnosis Era first appeared on Let's Talk Wellness Now.

Die BR Heimat-Kräuterexpertin Astrid Süßmuth und Andreas Estner gehen dem "Brot des Lebens" nach und entdecken, wie Hafer, Buchweizen, Kräuter und Blumen ihre Spuren in Gebäckformen, Festen und Redensarten hinterlassen haben.

Die Rauhnächte zwischen Wintersonnwende und dem Dreikönigstag gelten als eine Zeit voller Mystik, Aberglauben und jahrhundertealter Traditionen. Die BR Heimat-Kräuterexpertin Astrid Süßmuth ratscht mit Andreas Estner über die dunkelsten Nächte des Jahres.

How would a fight between Callas and Bechtold turn out? This is a historically mediocre version of Steelers/Ravens. The buzz has died down even from a year ago. However, this is a huge game for Tomlin. John Harbaugh is under some pressure, too. Can they ever get over the lump with Lamar Jackson? This is a massive swing for playoff odds. Do Steelers fans even want to make the playoffs? But a win will get fans excited again. Even if the Steelers lose out, they probably won't get a great draft pick. Joe really benefits from protein bars during the show. Lamar looked more healthy last week. Joe is taking the Ravens, as does Donny, albeit in a lower scoring game. Have the Steelers become the Eagles "Dream Team" in terms of disappointment? Will the Steelers attendance take a hit with another loss? Calls on the Steelers, one expecting a collapse and a Tomlin resignation. Another caller expects the Steelers to win in Baltimore. George Pickens reverted to his true self last night, but he still was probably worth keeping for one more year. "Timeliness" has been a problem for Pickens this season. We remember Antonio Brown in a hot air balloon. Ray Fittipaldo joins to discuss the struggles of both the Steelers and Ravens, if Mason is the best option currently. the outlook for Freiermuth, how much we'll see Adam Thielen, has TJ Watt lost a step, Heyward's play, the differences between the Steelers and Ravens in addressing their secondaries, free association, who has been the Steelers MVP? It's the internationally acclaimed numbers game: - 1,672, the Steelers yards differential over their past 17 games; 48 - Muth's percentage of snaps this season; 41.7 - Steelers conversion rate on 4th downs; 45 - Ben's TDs vs the Ravens; 22 - Lamar's record-season wins in December and later; 15 - Lamar's TD passes this year; 0 - Lamar Jackson has no TD passes in 3 straight starts; 1 - turnovers from Darius Slay; 5 - Lamar giveaways since week 11, the most in the NFL; 8 - receptions by Adam Thielen; 39.4 - Lamar's completion percentage on passes traveling 10 yards; 40 - the number of Steelers/Ravens games that have been one-possession contests; 39.3 - million dollars spent on Mark Andrews; 3 - since 2019, the Steelers are 3-30-1 when they lose the turnover battle. The Pirates made a trade for "the password", but Joe has a bad feeling about it. Donny seems more optimistic. This is definitely not a proven hitter. Who are some actual options for big-name hitters? Are the Pens going to be a playoff team? They've been the most entertaining team in town. Maybe the Pens should be a blueprint for the Steelers. Ron has been spotted in Pittsburgh. The Bechtold Breakdown with Sean - LeBron James 10-point streak ends, Penn State looks like it has it's next head coach. Steelers/Ravens quiz turned ugly. Donny prevailed but both guys struggled. College and NFL picks and Steelers over/unders.

It's the internationally acclaimed numbers game: - 1,672, the Steelers yards differential over their past 17 games; 48 - Muth's percentage of snaps this season; 41.7 - Steelers conversion rate on 4th downs; 45 - Ben's TDs vs the Ravens; 22 - Lamar's record-season wins in December and later; 15 - Lamar's TD passes this year; 0 - Lamar Jackson has no TD passes in 3 straight starts; 1 - turnovers from Darius Slay; 5 - Lamar giveaways since week 11, the most in the NFL; 8 - receptions by Adam Thielen; 39.4 - Lamar's completion percentage on passes traveling 10 yards; 40 - the number of Steelers/Ravens games that have been one-possession contests; 39.3 - million dollars spent on Mark Andrews; 3 - since 2019, the Steelers are 3-30-1 when they lose the turnover battle.

Ray Fittipaldo joins to discuss the struggles of both the Steelers and Ravens, if Mason is the best option currently. the outlook for Freiermuth, how much we'll see Adam Thielen, has TJ Watt lost a step, Heyward's play, the differences between the Steelers and Ravens in addressing their secondaries, free association, who has been the Steelers MVP? It's the internationally acclaimed numbers game: - 1,672, the Steelers yards differential over their past 17 games; 48 - Muth's percentage of snaps this season; 41.7 - Steelers conversion rate on 4th downs; 45 - Ben's TDs vs the Ravens; 22 - Lamar's record-season wins in December and later; 15 - Lamar's TD passes this year; 0 - Lamar Jackson has no TD passes in 3 straight starts; 1 - turnovers from Darius Slay; 5 - Lamar giveaways since week 11, the most in the NFL; 8 - receptions by Adam Thielen; 39.4 - Lamar's completion percentage on passes traveling 10 yards; 40 - the number of Steelers/Ravens games that have been one-possession contests; 39.3 - million dollars spent on Mark Andrews; 3 - since 2019, the Steelers are 3-30-1 when they lose the turnover battle.

Pflanzen spielen auch im Volksglauben eine große Rolle: Sie sollten Babys beschützen oder das Glück anziehen. Die BR Heimat-Kräuterexpertin Astrid Süßmuth ratscht mit Andreas Estner über Bräuche und Pflanzen im Volksglauben.

Salt Lake City vann omröstningen om vinter-OS 2002. Efteråt avslöjades en skandal som ledde till en av de största kriserna i den olympiska historien. Lyssna på alla avsnitt i Sveriges Radio Play. En dokumentär av Alexander Lundholm, 2025.Medverkande:Gunilla Lindberg, IOK-ledamot sedan 1996.Arne Ljungqvist, IOK-ledamot 1994-2011.Bengt Skött, Radiosporten.Åke Stolt, journalist och författare.Slutmix: Tim KellermanArkiv: SR, AP, KTVX, CBC, 2KUTV.

Haven of Rest food service manager, Jonell Muth, shared the substantial scope of the organization's food ministry, which prepares and serves about 300 to 400 meals daily to guests, including residents and community members. She highlighted the significant need for donations, noting that they use up to 900 small cans of vegetables for a single meal and need around 250 burgers for one meal. Key donation needs include canned goods (especially vegetables and fruits), snack items for work program lunches (such as chips, fruit cups, and individually wrapped snack cakes), coffee, instant oatmeal packets, and pastries for breakfast, as well as hot chocolate for the day rooms. Jonell emphasized the positive impact on guests, who often express gratitude and are blessed by the nutritious meals , and spoke about the "miracle" of God's provision, such as a recent donation of over 1,000 pounds of prepared food. The food service team is staffed by six full-time people and is supported by five to six volunteers daily. To help with donations or volunteer, listeners can call Jonell or the mission at 330-535-1563 and ask for the kitchen.

Ob sie mit den Römern kamen, sich nach Amerika aufmachten oder von dort aus unsere Städte erobern - Pflanzen sind wahre Globetrotter. Die BR Heimat-Kräuterexpertin Astrid Süßmuth ratscht mit Moderator Andreas Estner über Neophyten, Archäophyten und wilde Kräuter als unaufhaltsame Kulturfolger.

Mit dem Herbstanfang werden die Tage merklich kürzer, die Sonne steht tief. Dabei lassen ihre Strahlen das Herbstlaub bunt leuchten. Die BR Heimat-Kräuterexpertin Astrid Süßmuth wandert mit Johannes Hitzelberger durch den bayerischen Frühherbst.

This week Kate challenged Betsy to come up with a summer book to do on the podcast. And sadly, the book Betsy initially came up with was originally published in 2006 (and we have a 20-year rule on the books we can consider). Betsy found an alternative title instead, and it involves the combo of a Newbery Award winner (Hesse) with a Caldecott Award winner (Muth) (though we don't think either had won those respective awards when this book originally came out in 1999). It has been used in classrooms for years and years and years... but does it deserve to be called a classic? We discuss representation without firsthand personal experience and how well this book would fly with a publisher today. For the full Show Notes please visit: https://afuse8production.slj.com/2025/07/28/fuse-8-n-kate-come-on-rain-by-karen-hesse-ill-jon-j-muth/

2 - Who was causing a problem at the Joe Conklin Show last weekend? It was Chief Pat Molloy and his friends taking Dom's seats up front! Senator Muth might not be a fan of law enforcement, but now she wants front facing license plates! Did Chief Molloy sandbag Dan to get on the show? Does he like the front license plate? What kind of vanity plate should we get Dan? How revolutionary is their plate recognizing technology? 215 - Dom's Money Melody! 225 - As Penn continues to allow transgender rhetoric to flow in its classrooms, we are alerted to a scholar with an interesting name who says “sex is fake”, referring to one's physiology. Dinesh D'Souza had some thought on new Epstein revelations. 235 - Hank Johnson put out a song calling out Trump. 240 - Is Trump seriously equating the Epstein files to Russiagate? 250 - The Lightning Round!

12 - Keep sports for sports journalists only! A reporter asked Pat McAfee and a panel of athletes at the MLB All-Star Media Day in Atlanta about Jim Crow laws and election interference within the state back in previous elections. 1210 - Side - associated with prison/jail. 1220 - Just how in favor are Americans for mass deportation? Dom tells the story of a local illegal alien criminal's assault, but the neighborhood is outraged he might get deported! What did Alan Dershowitz say about Jeffrey Epstein with Cuomo? 1235 - EPA Administrator Lee Zeldin joins the program today. How excited is he to be with Dave McCormick at his big summit today in the Pittsburgh area? What was so important for Americans to know about both the environment and the economy when the EPA acted back on the 12th? What qualifies as a federal waterway? Why be completely transparent on geoengineering? What would Lee like the public to know regarding policy? Are they chemtrails or contrails? 1250 - Your calls at the end of the hour. 1 - Legal scholar and professor, as well as Jeffrey Epstein's former attorney, joins us to today to pour cold water all over the rumors and speculations around the case as the Trump administration has pivoted away from releasing the case's information, despite promising answers. Why does Alan think the judges, and not the Trump administration, are holding the information from the public? Are the people rumored to be on his guest list actually mentioned in the files? Did they even set foot on the island? What about Prince Andrew and his antics? How did Ghislane Maxwell embarrass not only herself, but other high profile people she said were hanging around Epstein? 110 - Is Christopher Columbus “provocative”? Are there icons that didn't do bad things as well? Who should be in the “Garden of Heroes”? 120 - Who is in Trump's “Garden of Heroes”? Who are the notable omissions 135 - Should there be a “Garden of Losers” for those who project anti–American Trump sentiment? Would someone decline an invitation to the “Garden of Heroes”? 150 - Your calls. Are Trump supporters trying to unmask corrupt elites? 2 - Who was causing a problem at the Joe Conklin Show last weekend? It was Chief Pat Molloy and his friends taking Dom's seats up front! Senator Muth might not be a fan of law enforcement, but now she wants front facing license plates! Did Chief Molloy sandbag Dan to get on the show? Does he like the front license plate? What kind of vanity plate should we get Dan? How revolutionary is their plate recognizing technology? 215 - Dom's Money Melody! 225 - As Penn continues to allow transgender rhetoric to flow in its classrooms, we are alerted to a scholar with an interesting name who says “sex is fake”, referring to one's physiology. Dinesh D'Souza had some thought on new Epstein revelations. 235 - Hank Johnson put out a song calling out Trump. 240 - Is Trump seriously equating the Epstein files to Russiagate? 250 - The Lightning Round!

Ein Balkon bietet Platz für unterschiedlichste Pflanzen: Kräuter, Beeren und Blumen bieten was fürs Auge und den Gaumen. Die BR Heimat-Kräuterexpertin Astrid Süßmuth und Moderator Andreas Estner streifen durch die Geschichte der Blumenbalkone.

Can a side hustle built on friendship and a love of travel become something bigger? Join Jason Muth, Rory Gill, and Ethan Sobel as they share the real story behind Prideaway Stays, their co-hosting venture in Provincetown. From a family dream of owning a Cape home to building a guest-first rental brand, this episode dives into the heart of short-term rental hosting. Discover how they scaled their business while staying personal, built community connections, and turned passion into purpose.

Psa 9:1  For the choir director; on Muth-labben. A Psalm of David. I will give thanks to the LORD with all my heart; I will tell of all Your wonders.Psa 9:2  I will be glad and exult in You; I will sing praise to Your name, O Most High.

Im Juni scheint das Wetter fast noch wichtiger zu sein als sonst - als entscheidender Faktor für Heumahd, Ernte und natürlich auch für das Sommervergnügen! Zusammen mit der BR Heimat-Kräuterexpertin Astrid Süßmuth ratscht Heimat-Moderatorin Hermine Kaiser über Wetterpflanzen.

Weight loss drugs are all over the news—and your social media feeds! But are they safe for teens? And when are they actually used? Pediatrician and registered dietitian Dr. Natalie Digate Muth explains how doctors are combining lifestyle changes with new medications to help adolescents manage their weight and avoid long-term health problems.    Learn more from Dr. Natalie Digate Muth   Send your questions to hello@pediatriciannextdoorpodcast.com or submit at drwendyhunter.com  Find products from the show on the shop page.   *As an Amazon Associate, I earn commission from qualifying purchases.    More from The Pediatrician Next Door:    Website: drwendyhunter.com   Instagram: @the_pediatrician_next_door  Facebook: facebook.com/wendy.l.hunter.75  TikTok: @drwendyhunter  LinkedIn: linkedin.com/in/drwendyhunter    This is a Redd Rock Music Podcast  IG: @reddrockmusic  www.reddrockmusic.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this powerful episode of The Digital Executive Podcast, Steve Muth shares the deeply personal story that led to the founding of ZEM Life Device—a wearable technology company driven by a mission to prevent overdose deaths. After losing his only son, Zachary, to fentanyl, Steve turned unimaginable grief into action by developing a discreet, stylish smartwatch that automatically administers emergency medication like Narcan.Steve explains how the ZEM Life Device combines smart design, real-time vitals monitoring, and modular cartridges to deliver life-saving medication precisely when it's needed most. With potential applications ranging from heart attacks to allergic reactions and even fertility treatments, ZEM is pioneering the future of medical automation.  Don't miss this inspiring conversation about technology, resilience, and saving lives.

Marienblumen, Hexenkräuter und Muttertagssträuße: Blütenzauber und Musik im Mai: Der Wonnemonat Mai ist ein brauchtumsreicher Frühlingsmonat. Die BR Heimat-Kräuterexpertin ratscht mit Andreas Estner über Maiandachten und Hexenkräuter.

Join Mattias Clymer with guest Jason Muth as he shares his journey from corporate life to running an LGBTQ+-friendly short-term rental business in Provincetown, MA. Discover key strategies for optimizing Airbnb properties and navigating the market post-COVID.Full article: https://www.unitedstatesrealestateinvestor.com/lgbtq-entrepreneurship-short-term-rental-mastery-with-jason-muth/Contact Jason MuthWebsite: Jason MuthPrideaway Stays: Prideaway StaysInstagram: @prideawaystays | @straightforwardstrsLinkedIn: Jason MuthThe REI Agent: https://reiagent.com

Mit Julius Muth (Company Shield Staffel #12 Folge #4 | #Marketing_021 Der Podcast über Marketing, Vertrieb, Entrepreneurship und Startups *** www.company-shield.com/ https://www.linkedin.com/in/julius-muth-7aa860b1/ *** Im neuesten "Marketing From Zero To One"-Podcast war Julius Muth zu Gast – Mitgründer und CEO von Company Shield, einem Berliner Cybersecurity-Startup, das sich auf moderne Sicherheitslösungen im Zeitalter der Künstlichen Intelligenz spezialisiert hat. Julius blickt auf Stationen bei PwC, Celonis und Project A zurück und bringt sowohl Beratungserfahrung als auch fundierte Tech- und Vertriebskenntnisse mit. Company Shield konzentriert sich auf den Faktor Mensch in der IT-Sicherheit – mit personalisierten, KI-basierten Simulationen realer Angriffe, die Mitarbeitende gezielt auf moderne Bedrohungen wie Deepfakes, Voice Cloning oder Phishing via WhatsApp vorbereiten. Im Gespräch berichtete Julius, wie er mit zwei Ex-Kollegen aus der Celonis-Zeit gründete, welche Ideen Company Shield vorangingen, und wie sie mithilfe eines ungewöhnlichen MVP-Ansatzes – per Brief und persönlichem Pitch – die ersten Kunden gewannen. Besonders spannend: die Kombination aus Automatisierung und KI, mit der Angriffe simuliert, personalisiert und sofortige Lernmomente geschaffen werden. Auch die Nutzung von KI im Alltag, etwa für Research, interne Tools oder Produktentwicklung, wurde diskutiert. Mit dabei war wieder Michael Högemann, der insbesondere nach Einsatzszenarien von KI für Company Shield fragte. *** 01:58 – Was Company Shield macht und warum der Mensch im Zentrum steht 03:37 – Stationen vor der Gründung: PwC, Celonis, Start-up-Projekte im Studium 08:45 – Erste Gründungserfahrungen und der Weg zur Selbstständigkeit 10:14 – Einstieg bei Celonis und Rolle im internationalen Vertrieb 14:56 – Gründungsidee und strukturierte Ideation mit Brief-Experimenten 18:25 – Warum Cybersecurity sofort Resonanz erzeugte 22:14 – Der erste zahlende Kunde und das improvisierte MVP 25:12 – Herausforderungen im B2B-Vertrieb und Early Adopter 30:08 – Brief, E-Mail, Anruf – der Mix macht's 40:03 – Einsatz von Deepfakes im Vertrieb (und wo es rechtlich kritisch wurde) 42:36 – Seriosität vs. Kreativität: Die richtige Balance im Start-up-Vertrieb 44:12 – Über 20 Angel-Investoren, darunter die Celonis-Gründer und Mario Götze 44:55 – Warum es Company Shield ohne KI nicht gäbe 49:10 – Deepfake-Angriffe in der Praxis: Der Fall Arup und andere Beispiele 50:53 – Wie das Training mit Company Shield konkret aussieht 52:18 – Technische Umsetzung: Automatisierung, Sprachmodelle, Datenintegration 54:03 – Einsatz von KI im internen Arbeitsalltag 56:57 – Effektivste Tools und KI-Anwendungen im Start-up 58:31 – Der „KI-Zwilling“ als nächster großer Schritt in der Produktentwicklung 59:40 – Warum Cybersecurity nicht mission-critical, aber trotzdem entscheidend ist 1:02:00 – Tipps gegen Cyberangriffe & menschliche Schwächen im System *** Die Zeitangaben können leicht abweichen.

Die Isar fließt vom Karwendel bis zur Donau und kommt auf ihrem Weg durch Städte wie München sowie urbayerische Landschaften. Die BR Heimat-Kräuterexpertin Astrid Süßmuth nimmt uns im Ratsch mit Andreas Estner entlang der Isar.

The One where Dave and Rich read Moonshadow and even Dave is dazzled and at a loss for words! Read the book and listen to the show! Please support the show on Patreon! Every dollar helps the show! https://www.patreon.com/SignalofDoom Follow us on Twitter: @signalofdoom Dredd or Dead: @OrDredd Legion Outpost: @legionoutpost Follow Dave on Twitter: @redlantern2051

Welcome to our latest episode! Today, we're joined by Jason Muth, Co-Founder and Director of Customer Experience at Prideaway Stays. Jason is a 31x Airbnb Superhost, 29x Vrbo Premier Host, and a full-time entrepreneur who transitioned from a corporate media career to scaling a successful short-term rental and co-hosting business. His story is filled with insights on intentional growth, hospitality, and building a business that aligns with your lifestyle and values.In this episode, Jason shares how one uncomfortable couch and an allergy to cats led to the purchase of his first short-term rental in 2016—and how that one home turned into five owned properties and a thriving co-hosting operation with 17 listings. He walks us through the lessons learned from a major property flood, why having the right insurance partner made all the difference, and how installing generators across his portfolio became a strategic move. Jason also unpacks the launch of Prideaway Stays, his Provincetown-focused management company that blends hospitality, niche branding, and community engagement.If you're curious about how to pivot into co-hosting, build a business that reflects your values, or simply hear how a seasoned host navigated the challenges of growth, this episode is for you. Tune in now to learn how Jason scaled from one rental to a robust hospitality brand—and what he wishes more short-term rental owners understood about success!TIMESTAMPS01:00 – Spring updates and business expansion04:58 – Guest intro: Jason Muth06:08 – How an uncomfortable couch sparked Jason's first short-term rental09:05 – From one rental to five: Jason's early investment journey13:28 – Transitioning from W-2 to full-time entrepreneur17:00 – Using DSCR and vacation loans to scale19:11 – Cost segregation and maximizing depreciation22:01 – The guest-caused flood and $130K in damages24:50 – Why proper insurance is worth every penny29:14 – Installing generators across all properties31:03 – Messaging guests and preparing for power outages33:36 – Neighbor relationships and protecting the business39:02 – Launching Prideaway Stays in Provincetown42:55 – Why niche focus matters: Knowing your target guest48:03 – Second homeowners vs. investors in New England markets50:47 – Giving back and community partnerships at Prideaway53:45 – Final thoughts and where to connect with JasonConnect with the Guest:Website: https://www.prideawaystays.com/Linkedin: https://www.linkedin.com/in/jasonmuth/Instagram: https://www.instagram.com/jasonmuth/Facebook: https://www.facebook.com/jasonmuth/Youtube: https://www.youtube.com/@smartstayshow#ShortTermRentals #AirbnbSuperhost #STRCoHosting #VacationRentalTips #EntrepreneurJourney

Coats in Cars - Sidney Crosby eats rotisserie chickens - We check in with the Pittsburgh Scanner... Everyone doing ok out there? - Bird Watching - Steelers locker clean out... Russ wants to come back, We milk a Muth, and T.J. Watt is training with a Fayette County bear - Everyone getting on Red Note - The Mt. Washington billboard that overlooks Pittsburgh has changed so we went right to the Facebook comments - Have anything fun for the show... Listen on iHeartRadio and send us a talkback messageSee omnystudio.com/listener for privacy information.

Steelers eh.. Steelers Monday after It is all over - Steelers Facebook comments - Coach Tomlin, Sad Cam, Sad T.J., George Picken, Russ, Naj, Muth, Joey Porter after the loss - TikTok might be done this week - Bluejays aren't blue?? - Does Ben look like he checks his drive-thru order before he drives away - If you listen to the podcast on iHeartRadio hit the little mic and send us a talkback message we love hearing for you all.See omnystudio.com/listener for privacy information.

In this episode of The Healers Café, Manon Bolliger, FCAH, RBHT, speaks with Dr. Deb Muth about embracing integrative medicine, overcoming personal health challenges, and empowering practitioners to build thriving practices through holistic care.   For the transcript and full story go to: https://www.drmanonbolliger.com/dr-deb-muth        Highlights from today's episode include:   Dr. Deb Muth  09:20 Instead of us talking about disease, let's talk to the client about what it is they want to have success in and in that area, then it allows the naturopath to open up all the different tools that they have in their toolbox to help them reach that   Manon Bolliger  09:56 we're always focused on the pain or the symptom, rather than the reason you want to have no pain, you know? And when you focus people on the reason, it changes     Dr. Deb Muth  26:43 But I've never seen somebody heal who can't heal their spiritual or mental health, but they can heal their physical side. They're always stuck in that Limbo if they can't feel heal their body as a whole. And I think that's what's so   Dr. Deb Muth, NP, ND, MSNH, Master Herbalist, Shaman:   Founder of Serenity Health Care Center | Naturopathic Doctor | Author | Podcast Host | MS Recovery Advocate Dr. Deb Muth is a leading authority in integrative and functional medicine, known for her groundbreaking work in chronic illness, hormone optimization, and mitochondrial health. As the founder of Serenity Health Care Center—the largest integrative medical practice in the Midwest—Dr. Muth blends advanced medical science with ancient healing practices. With over 23 years of experience, she specializes in complex conditions, empowering patients to reclaim their health through personalized, root-cause-focused care. In 2021, after being diagnosed with Multiple Sclerosis, Dr. Muth combined her deep medical expertise with her spiritual practice to challenge the diagnosis. Rejecting conventional treatment paths, she developed a revolutionary recovery protocol that targeted the underlying causes of her illness. This unique approach, which fused cutting-edge science with spiritual insight, enabled her to fully reverse her white matter disease in just 18 months. Dr. Muth's story of recovery is now an inspiration for patients and practitioners alike. As the host of the popular podcast Let's Talk Wellness Now, Dr. Muth shares the latest advancements in health, wellness, and longevity with a global audience. She is also an accomplished author and educator, offering elite training programs that empower other healthcare professionals with the advanced protocols and innovative therapies she has pioneered. Core purpose/passion: My passion is reversing neurological disease by optimizing the body. I am a medical detective helping people find the answers to their symptoms is my passion. Website | Facebook | Instagram | LinkedIn | Twitter | YouTube      ABOUT MANON BOLLIGER, FCAH, RBHT   As a de-registered (2021) board-certified naturopathic physician & in practice since 1992, I've seen an average of 150 patients per week and have helped people ranging from rural farmers in Nova Scotia to stressed out CEOs in Toronto to tri-athletes here in Vancouver.   My resolve to educate, empower and engage people to take charge of their own health is evident in my best-selling books:  'What Patients Don't Say if Doctors Don't Ask: The Mindful Patient-Doctor Relationship' and 'A Healer in Every Household: Simple Solutions for Stress'.  I also teach BowenFirst™ Therapy through and hold transformational workshops to achieve these goals.   So, when I share with you that LISTENING to Your body is a game changer in the healing process, I am speaking from expertise and direct experience".   Manon's Mission: A Healer in Every Household!   For more great information to go to her weekly blog:  http://bowencollege.com/blog.    For tips on health & healing go to: https://www.drmanonbolliger.com/tips   Follow Manon, on social media! FB: https://www.facebook.com/DrManonBolliger/  IG: https://www.instagram.com/drmanonbolliger/    Follow Manon on Social – Facebook | Instagram | LinkedIn | YouTube | Twitter | Linktr.ee | Rumble       ABOUT THE HEALERS CAFÉ:   Manon's show is the #1 show for medical practitioners and holistic healers to have heart to heart conversations about their day to day lives.   Subscribe and review on your favourite platform:   iTunes | Google Play | Spotify | Libsyn | iHeartRadio | Gaana | The Healers Cafe | Radio.com | Medioq |     Follow The Healers Café on FB: https://www.facebook.com/thehealerscafe     Remember to subscribe if you like our videos. Click the bell if you want to be one of the first people notified of a new release.   * De-Registered, revoked & retired naturopathic physician after 30 years of practice in healthcare. Now resourceful & resolved to share with you all the tools to take care of your health & vitality!

In this episode of The Smart Stay Show, we're diving into the critical role of signage in short-term rentals. From the must-have Wi-Fi sign to rules about smoking, plumbing, and pets, this episode is packed with practical advice to help you create a seamless guest experience. We'll discuss how to balance necessary information with tasteful design, avoid the pitfalls of overwhelming guests, and even incorporate humor and creativity to make your signs stand out. Tune in for actionable tips to protect your property, keep guests informed, and enhance their stay! Things discussed in this episode: Importance of signage in short-term rentals to reduce guest questions and enhance the guest experience. Wi-Fi information signs, including network name and password or login instructions. Smoking rules signs, indicating whether smoking is allowed indoors, on the premises, or not at all. Signs reminding guests not to flush anything except toilet paper, to prevent plumbing issues. Signs for pet-friendly properties, requesting guests keep pets off beds and furniture. Thermostat instruction signs to prevent guest confusion and HVAC system damage. QR codes linking to an interactive guest guide for easy access to property information. Incorporating humor and artistic flair into sign design to make them more appealing to guests. Signs for outdoor amenities like hot tubs, fire pits, and fireplaces to ensure proper usage. Signs for specialized features like butcher block countertops, providing care instructions. Get in touch with Jason: Facebook - https://www.facebook.com/jasonmuth Linkedin - https://www.linkedin.com/in/jasonmuth/ Website - https://www.smartstayshow.com/ https://www.straightforwardstrs.com/ https://prideawaystays.com/ #SmartStayShow #realestate #realestateinvestor #realestateagent #RealEstateInvesting #AirbnbHostTips #ShortTermRentalSignage #GuestExperienceEnhancement #PlumbingProtection #PetFriendlyRules #ThermostatInstructions #QRCodeGuides #CreativeSignDesign #IdiotProofingYourRental #ShortTermRentalHacks Follow Us! Join Jason Muth of Prideaway Stays and Straightforward Short-Term Rentals and Real Estate Attorney / Broker Rory Gill for another episode of SmartStay Show! Following and subscribing to SmartStay Show not only ensures that you'll get instant updates whenever we release a new episode, but it also helps us reach more people who could benefit from the valuable content that we provide. ***** SmartStay Show Website and on Instagram and YouTube Prideaway Stays Website and on Facebook and LinkedIn SmartStay Coaching Website and on Instagram Straightforward Short-Term Rentals Website Attorney Rory Gill on LinkedIn Jason Muth on LinkedIn ***** This podcast and these show notes are not legal advice, but we hope you find both entertaining and informative. Hospitality.FM SmartStay Show is part of Hospitality.FM, a podcast network dedicated to bringing the best hospitality-focused podcasts to those in and around the industry, from Food + Beverage, Guest Experience, Diversity & Inclusion, Tech, Operations, Hotels, Vacation Rentals, Real Estate Law, and so much more!

In this episode, We dive into the crucial role of location in short-term rental success. From being close to key attractions like beaches and national parks to considering the charm of quieter residential neighborhoods, I'll walk you through the factors that can make or break your rental's performance. I also share my experiences hosting in Provincetown, Massachusetts, and offer practical tips for enhancing the value of your property—whether it's upgrading amenities, marketing hidden gems in your area, or catering to your guests' specific needs. Tune in to learn how to unlock the full potential of your short-term rental through the power of location! Things discussed in this episode: The importance of location in short-term rentals and how it can impact rental performance. How location affects the value and rental rates of properties, particularly lakefront and beachfront properties. The benefits and potential drawbacks of being in prime locations, such as near beaches or lakes. Considerations for choosing the right location when purchasing a new short-term rental property. The impact of neighborhood and community culture on the success of short-term rentals. Strategies for promoting lesser-known local attractions and unique features of an area. The importance of upgrading the property's own amenities and experiences to enhance the guest experience. The use of great photography and accurate marketing to highlight a property's location and proximity to attractions. Understanding the target market and catering to their specific needs and preferences. Leveraging a property's proximity to popular destinations by positioning it as a "base camp" for day trips and activities. Get in touch with Jason: Facebook - https://www.facebook.com/jasonmuth Linkedin - https://www.linkedin.com/in/jasonmuth/ Website - https://www.smartstayshow.com/ https://www.straightforwardstrs.com/ https://prideawaystays.com/ #SmartStayShow #realestate #realestateinvestor #realestateagent #RealEstateInvesting #AirbnbHostTips #AirbnbSuperhost #ShortTermRentalSuccess #ShortTermRentals #LocationMatters #AirbnbHosting #PropertyInvesting #VacationRentals #CommunityDynamics #GuestExperience #MarketingTips #TargetMarket #DestinationTravel Follow Us! Join Jason Muth of Prideaway Stays and Straightforward Short-Term Rentals and Real Estate Attorney / Broker Rory Gill for another episode of SmartStay Show! Following and subscribing to SmartStay Show not only ensures that you'll get instant updates whenever we release a new episode, but it also helps us reach more people who could benefit from the valuable content that we provide. ***** SmartStay Show Website and on Instagram and YouTube Prideaway Stays Website and on Facebook and LinkedIn SmartStay Coaching Website and on Instagram Straightforward Short-Term Rentals Website Attorney Rory Gill on LinkedIn Jason Muth on LinkedIn ***** This podcast and these show notes are not legal advice, but we hope you find both entertaining and informative. Hospitality.FM SmartStay Show is part of Hospitality.FM, a podcast network dedicated to bringing the best hospitality-focused podcasts to those in and around the industry, from Food + Beverage, Guest Experience, Diversity & Inclusion, Tech, Operations, Hotels, Vacation Rentals, Real Estate Law, and so much more!

Since 2021, every single active voter in Nevada received a mail-in ballot. Chuck Muth, president of the Citizen Outreach Foundation in Nevada, tells The Federalist's Senior Elections Correspondent Matt Kittle that dozens of voters have been found on the rolls with home addresses listed at casinos, bars, and other locations in violation of the law. So what can be done? Muth breaks it down for "The Federalist Radio Hour."If you care about combatting the corrupt media that continue to inflict devastating damage, please give a gift to help The Federalist do the real journalism America needs.