Podcasts about Shortening

Do the many clinical trials into high-dose vitamin C prove it can actually treat the common cold and cancer, rather than just boost the immune system? Why is there ongoing scepticism? Why are multifactorial chronic diseases so hard to study in clinical trials? What is the right dosage to get the best results from vitamin C?In this episode we have the often misunderstood topic of Vitamin C as an antioxidant to get clear on, particular the high-dose approach and particularly delivered intravenously. Despite a very clear consensus that Vitamin C is a great booster to immune function, research that shows that it helps fight the common cold or flu have been dismissed by doctors and medical researchers; as well as claims that higher doses can increase its efficacy. Other claims that Vitamin C can help fight cardio-vascular disease and even cancer have been with even greater scepticism. So what exactly can vitamin C do to assist our immune function to fight disease, and why is there so much confusion about the answer given the high quantity of clinical trials data?Fortunately today's guest has exactly the right skill set and research knowledge to separate the science from the here-say, medical doctor and orthomolecular medicine researcher, Dr. Richard Z Cheng. Dr. Cheng has a PhD in biochemistry and molecular biology; he's served as a doctor in the US military; he has consulted for the National Cancer Institute, and presented at the National Institute of Health (NIH); he has conducted clinical trials; He is the editor in Chief of the Orthmolecular Medicine New Service; He is also a fellow of the American Academy of Anti- Aging medicine; and has run anti-aging and regenerative medicine clinics in both China and the US for over 20 years.What we discuss:00:00 Intro05:15 Most animals produce Vitamin C in the body, but not primates.06:00 Oxidation & Redox: Giving or receiving an electron.11:00 After reducing oxidation the body recycles it back into vitamin C.14:00 Teamwork: sharing electrons between nutrients and vitamins.18:20 Conventional consensus: good for prevention but not treatment.21:00 Over 80K papers on Vit C on Pub Med!21:30 Linus Pauling Intravenous Vitamin C for cancer and heart disease.27:00 Shortening of common cold and lowering of symptoms - Harri Hemila.29:00 Low dose studies dilute the data on the efficacy of the high dose studies.31:00 Intravenous treatment allows much higher doses safely.33:00 Differences in absorption between IV and oral application.35:20 Pro-oxidant effect only possible at IV high dose.36:30 IV clinical trials.39:20 Cytokine storm cascades in acute respiratory distress.44:00 High Dose IV Vitamin C saved lives in China during Covid 19.50:00 Attacks following Richard's NIH presentation on Vitamin C during covid.57:00 Cardio vascular disease - Vit. C research history.01:01:00 Collagen Synthesis for vascular walls & Vitamin C deficiency.01:07:20 Is the taboo for life style medicine lifting?01:09:30 Issues of gold standard RCT trials not working for multifactorial integrative interventions.01:16:00 Recommendations for preventative use of Vitamin C for listeners. References:E Cameron & Linus Pauling - 'Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer', 1976E.T. Creagan, 'Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer', 1979Harri Hemilä - over 200 meta-analyses and clinical trialsPing Chen et al. 'Pharmacokinetic Evaluation of Intravenous Vitamin C'Richard Z Cheng, ‘Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)?'KU Cancer Center researchers announce study of high-dose intravenous vitamin C to treat muscle-invasive bladder cancer, 2024National Cancer Institute overview of IV Vitamin C cancer research.

Want to know how your business is going? ⁠Take this quiz to know⁠: https://app.jenniferdawncoaching.com/freedomquiz-page In this episode, Jennifer and Will Fuller dive into the mindset and vision behind building a business that actually feels good to run. Will shares the 10-year future snapshot that changed everything for him, why simplicity matters as you grow, and how to access the inner guidance most people overlook. If you're ready for clarity, perspective, and real wisdom from a seasoned leader, this conversation will give you exactly that. TIMESTAMPS: 1:52 — How a millwork company became change agents. 2:56 — The importance of practicing 3D chess thinking. 4:13 — Why the price of stagnation is often too high. 5:41 — Strategy for market consumption after a competitor closed. 6:37 — Outgrowing old success strategies and company evolution. 7:37 — Shortening the learning curve for future generations. 16:11 — The unexpected 10-year vision that prompted change. 17:16 — The mission to simplify business complexity. 23:46 —  The mission to simplify business complexity. 28:40 — How to practice leaning into inner guidance. 30:52 — Why you must approach problems with the right expectation. 34:02 — The Business Lesson of the episode LINKS: Connect with Will Fuller: • LinkedIn: https://www.linkedin.com/in/willfuller/ • Website: https://www.acaciaoriginals.com/ Connect with Jennifer Dawn: • LinkedIn → / jenniferdawn • Instagram → https://www.instagram.com/jenniferdaw... • YouTube → / @jenniferdawncoaching Schedule a call with Jennifer ⁠here⁠ https://jenniferdawncoaching.com/sche... Want to be a podcast guest? https://forms.gle/hgS1wUWy6Y4ybJ319 Visit our website ⁠here⁠ https://jenniferdawncoaching.com/

BUFFALO, NY — October 27, 2025 — A new #research paper was #published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles.” In this study led by first author Jessica Louzame Ruano and corresponding author Maria A. Blasco from the Spanish National Cancer Centre (CNIO), researchers investigated the role of TRF1, a protein known for protecting telomeres, in regulating whole-body metabolism. The results suggest that TRF1 influences metabolic health through mechanisms unrelated to its known function in telomere maintenance. Obesity and metabolic disorders are major health concerns, especially as people age. To explore TRF1's role beyond telomere protection, the research team studied both normal mice and genetically modified mice that lacked TRF1. Mice without TRF1 remained leaner over time, resisted fat accumulation, and showed healthier blood sugar and insulin levels compared to normal mice. Importantly, these benefits occurred without any detectable shortening of telomeres. The leaner body composition in TRF1-deficient mice was not due to reduced food intake or increased physical activity. Instead, the fat loss appeared to result from biological changes in how energy was processed and stored. Male mice without TRF1 gained less weight and had lower LDL cholesterol levels, even on a high-fat diet. Female mice showed milder effects, reflecting known sex-based differences in susceptibility to diet-induced obesity. This highlights the importance of including both sexes in metabolic research. “Major metabolic pathways related with energy production and regulation of metabolism homeostasis were also found downregulated in Trf1-deficient mice.” Gene expression analysis in the liver revealed shifts in several key pathways. Genes related to fat production, energy generation, and muscle growth were downregulated, while genes linked to inflammation and cholesterol synthesis were upregulated. The mice also showed signs of higher energy expenditure and a shift from using fat to protein as an energy source, possibly due to their reduced fat reserves. However, some older mice developed mild liver stress, including fibrosis and DNA damage, suggesting a possible long-term trade-off. Overall, this study expands the understanding of how telomere-related proteins influence more than just cellular aging. By identifying a connection between TRF1 and metabolism, the research opens new possibilities for targeting TRF1 or its pathways to address obesity and related conditions. Still, further studies are needed to clarify how TRF1 affects fat development and whether similar effects occur in humans. DOI - https://doi.org/10.18632/aging.206320 Corresponding author - Maria A. Blasco — mblasco@cnio.es Abstract video - https://www.youtube.com/watch?v=7AG3TBgDZIw Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206320 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Trf1, metabolism, leaner, fat, telomeres To learn more about the journal, visit https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

In this powerful episode of Insight is Capital, host Pierre Daillie sits down with Shana Sissel, CEO and Founder of Banríon Capital Management, widely known as the “Queen of Alternatives.” From breaking barriers in the world of alternative investments to surviving and thriving through profound personal adversity, Shana's story is one of resilience, purpose, and innovation. She reveals how Banríon was built by advisors, for advisors — an open-architecture platform designed to help wealth managers make sense of alternatives and scale their use effectively. Shana and Pierre dig deep into what makes advisors successful, why emotional intelligence (EQ) matters more than ever, and how Banríon is redefining the bridge between asset managers and advisors. The conversation takes a personal and moving turn as Shana recounts launching her firm while battling stage-four cancer and the unexpected loss of her fiancé. Her perspective on perseverance, purpose, and leadership transforms this episode into an unforgettable masterclass in both business and humanity. 3 Key TakeawaysRedefining “Alternative” Investing: Alternatives aren't a niche — they're a mindset. Shana explains how advisors can unlock new opportunities by thinking beyond the 60/40 portfolio and embracing a structure-agnostic, relationship-driven approach to investment solutions. Resilience and Purpose in Leadership: From personal loss to life-threatening illness, Shana's story exemplifies how grit, purpose, and optimism can fuel innovation and success. Her journey underscores that true leadership is built in the face of adversity. The Advisor's EQ Advantage: Success in wealth management isn't about IQ — it's about empathy. Advisors who master emotional intelligence and authentic relationship-building are the ones who stand apart in an increasingly automated industry.Timestamped Chapters00:00 Pierre's intro: Meet Shana Sissel — The Queen of Alternatives02:00 How Shana accidentally discovered finance (from sports to Morgan Stanley)06:00 Why EQ matters more than IQ in financial advising09:30 What makes Banríon Capital's platform different — built by advisors, for advisors13:00 The truth about product design, relationships, and client trust17:00 Why most alt platforms miss the mark — and how Banríon bridges the gap21:00 Helping smaller managers and advisors connect efficiently33:00 Shortening the sales cycle: How Banríon streamlines due diligence36:00 The origin story — how Banríon evolved from concept to platform44:00 Facing tragedy: Shana's journey through grief and cancer diagnosis49:00 How resilience and attitude became her greatest business assets56:00 The new investing era — why alternatives are essential today1:06:00 Building resilient portfolios: Private credit, sports, and managed futures1:13:00 The rise of return stacking and the future of portfolio construction1:18:00 Closing reflections — living with purpose and building legacyWhere to find Banrion Capital ManagementBanrion Capital Management - https://www.banrioncapital.com/Shana Sissel on Linkedin - https://www.linkedin.com/in/shsissel/

Farmers have shortened up crop rotation for a number of reasons. Oilseed agronomy research scientist Patrick Molecki is with Agriculture and Agri-Food Canada at the Saskatoon Research and Development Centre. He there are numerous issues popping up because of this practice including herbicide resistance in weeds and increased disease pressure including blackleg and fusarium head blight.Patrick says the continuing practice will have long term implications.There tends to be a focus on the negative environmental aspects of farming like the greenhouse gases emitted from vehicles, fertilizers, and grain transportation. But there is new work showing this impact can be offset by planting trees. It's estimated more 21.3 million tonnes of carbon-dioxide-equivalent is stored in Saskatchewan’s 60,000 km of shelterbelts, representing about $639 million in total economic value under the federal $30 per tonne carbon-dioxide-equivalent pricing system.Bryan Mood with USask will discuss a new app that is designed to show the economic value of shelterbelts while helping landowners determine the best trees to grow.See omnystudio.com/listener for privacy information.

Off The Bench is back weekdays from 10a to 11a followed by The Stone Shields Show from 11a to noon! In a game that started as a nightmare and ended in futile desperation, the Cincinnati Bengals fell 37-24 to the Detroit Lions on October 5, 2025, at Paycor Stadium, extending their skid to three straight defeats. What began as a 28-3 halftime rout—fueled by Detroit's explosive backfield duo of Jahmyr Gibbs and David Montgomery tying an NFL record with their 14th combined touchdown—devolved into a fourth-quarter mirage for Bengals fans. Cincinnati, now 2-3, has been outscored 113-37 over this brutal stretch, a stark reminder of life without injured star Joe Burrow. Quarterback Jake Browning, filling in admirably during a 2023 late-season surge, looked utterly lost under center. He threw three interceptions—two deep in Bengals territory that gifted Detroit short-field touchdowns—before salvaging his stat line with 251 yards and three fourth-quarter scores to Ja'Marr Chase and Tee Higgins. Those late strikes, including a 65-yard bomb to Chase, trimmed the deficit to 35-24 and sparked brief "Stripe the Jungle" chants amid boos that rained down after his third pick. But it was too little, too late; a failed onside kick and safety sealed the embarrassment. Browning now ranks second in the NFL with eight picks, his adjusted EPA per dropback a woeful -0.44, dead last among qualifiers. Head coach Zac Taylor shouldered blame for the slow starts but doubled down on faith in Browning, saying, "I believe Jake can win games for us." Yet, postgame whispers of accountability rang hollow: Taylor admitted hearing bench calls from the crowd, while Browning owned his "awful" play, deferring any changes to the staff. The leash? Shortening fast. With Burrow sidelined until at least December from toe surgery, rumors swirl of an upgrade. Analysts urge trading for a veteran like Russell Wilson or the benched Kirk Cousins to stem the bleeding—Brett Rypien, the roster's only other QB, boasts a 4-9 TD-INT ratio in limited action. Facing Green Bay next, then primetime tilts against the Jets and Steelers, Cincinnati's 2-3 perch in a wobbly AFC North (Ravens and Browns at 1-4) offers a lifeline. But sticking with Browning risks irrelevance; the front office must act, or this season crumbles before Burrow's return. The Bengals' Super Bowl window creaks open—don't slam it shut with indecision. Music from #InAudio: https://inaudio.org/ Track Name Holy (Trap). Music from #InAudio: https://inaudio.org/ Track Name Exercise (Rock). #Bengals #BengalsRumors #BengalsNews

Extending our healthy years isn't just about eating well and exercising — it's also about the systems around us. Social policies, public health programs, and access to care all play a huge role in how long and how well we live. In this episode, we look at what it takes to improve health for everyone, everywhere. We each have personal choices to make, but what about the bigger picture?Dr. Tyler Evans is a physician, infectious disease specialist, and author of Pandemics, Poverty and Politics: Decoding the Social and Political Drivers of Pandemics from Plague to Covid-19.In a wide-ranging conversation with Peter Bowes, Dr. Evans connects stalled life expectancy to weakened safety nets, unequal access to healthcare, and the cracks exposed by recent global crises. He emphasizes practical action — meeting people where they are, funding prevention, and rebuilding systems that can spot and stop health threats early. Drawing on his experience from Los Angeles's Skid Row to global epidemic response, Evans calls for a non-partisan, evidence-driven approach that focuses on those most at risk — because when the most vulnerable communities thrive, everyone benefits.----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/ PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

For decades, nuclear has struggled with cost overruns and delays — Georgia's Vogtle plant being the latest example. Kairos Power co-founder and CEO Mike Laufer thinks the solution is to flip the script: focus first on non-nuclear demonstrations and then iterate quickly.  It's a counterintuitive and potentially risky strategy . Rapid iteration isn't the way engineers or funders like the DOE have traditionally developed nuclear plants. Kairos also combined two technologies — TRISO fuel and molten salt — into a first-of-a-kind design. Theoretically it would be safer, but Kairos was also tackling one of the hardest problems in engineering: building a reactor from scratch. After eight years of development, its approach has led to three engineering test units, a novel contracting model with the Department of Energy, and a landmark partnership with TVA and Google to deliver nuclear power to data centers.  So how did Kairos pull it off? In this episode, Lara talked with Mike about how Kairos executed its ambitious iterative approach without overextending itself. They also cover why Kairos chose to vertically integrate and build its own in-house machine shop, plus what technical setbacks taught the team.  Credits: Hosted by Lara Pierpoint. Produced by Daniel Woldorff and Erin Hardick. Edited by Anne Bailey. Technical direction by Sean Marquand. Stephen Lacey is executive editor. The Green Blueprint is a co-production of Latitude Media and Trellis Climate. Subscribe on Apple, Spotify, or anywhere you get podcasts. For more reporting on the companies featured in this podcast, subscribe to Latitude Media's newsletter.

On this Special Presentation episode, Rick Zamperin and Simoni Lawrence break down all the future Canadian Football League game changes that were laid out by CFL Commissioner Stewart Johnston during his press conference on Monday in Toronto as the CFL is making a bold move to evolve the game with a set of changes centred upon entertainment and innovation.Key Takeaways:The CFL is implementing significant rule changes for 2026 and 2027.The 35-second play clock aims to improve game flow.Moving team benches to opposite sides enhances player safety and fan experience.Tweaking the Rouge rule requires teams to earn points more competitively.Shortening the end zone to 15 yards will impact offensive strategies.Shrinking the field from 110 to 100 yards will change kickoff dynamics.These changes are designed to increase scoring and excitement in games.Fans will have a better view of the action without goalposts obstructing sightlines.The changes reflect a shift towards a more dynamic and entertaining game.Simoni Lawrence emphasizes the importance of skilled play and competitive integrity.Chapters00:00CFL Rule Changes Overview02:53Fan Experience Enhancements06:03Impact of the 35-Second Play Clock08:55Tweaking the Rouge Rule11:52End Zone Adjustments14:54Shrinking the Field Dimensions17:50Overall Impact and Future of CFLGET YOUR TICKETS HEREThe Ticats Audio Network provides Hamilton Tiger-Cats fans with the most comprehensive, entertaining and informative news and information about their favourite football team. Featuring Steve Milton, Mike Daly, Bubba O'Neil, Courtney Stephen, Simoni Lawrence, Mike Morreale, Rob Hitchcock, Mike Daly, Louie Butko, Troy Durrell, Ticats players, coaches and front office personnel, and many more. Regular shows include Ticats Today, Ticats This Week, Tiger-Cats Game Day, Tiger-Cats Pregame, Tiger-Cats At The Half, Tiger-Cats Postgame, Speaking With The Enemy, Morreale & Hitch, The Milton Report, What Happened with Simoni Lawrence, and so much more. Ticats Audio Network content can be found on the Tiger-Cats YouTube channel, Spotify, Apple Podcasts, at listen.ticats.ca and anywhere else you find podcasts. Please follow, like, leave a review wherever you find our content, and follow the Hamilton Tiger-Cats social media channels to keep up to date with all Ticats Audio Network content. Twitter: @TicatsInsta: @hamiltontigercatsTikTok: @hamiltonticatsFacebook: cfltigercatsYouTube: ticatstvchannel

Send us a textBill Davis is the Aviation Maintenance Technology Coordinator at George Stone Technical College. In this episode, he shares how a special collaboration with King Aero has delivered a cutaway version of a real turbine engine into the classroom for hands-on learning, streamlining instruction and changing lives.Guest: Bill Davis https://www.escambiaschools.org/Page/6125 Learn more about Escambia County School District: https://www.escambiaschools.org/Find additional links: https://www.voicesunitedineducation.com/podcast-episodesHost: Meredith Hackwith Edwards

In this episode, Dr. Bill Andrews joins Dr. Buck Joffrey to discuss the critical role of telomeres and telomerase in aging and cellular health. He explains how telomeres shorten with each cell division, leading to aging and cellular senescence. Dr. Andrews emphasizes the importance of inducing telomerase to potentially reverse aging and shares insights from his research on telomerase inducers. He also addresses the challenges in longevity research, the relationship between telomeres and the hallmarks of aging, and the potential of gene therapy. The conversation concludes with a discussion on lifestyle factors that can influence aging and the future of aging research. Learn more about Dr. Bill Andrews: https://sierrasci.com/dr-bill-andrews/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

What is the best way to cool off your shortening for transportation? We have SPACE for you at the National Street Food VendorsAssociation! Support, Promotion, Advocacy, Community, Education all on onesite. https://nsfva.org/ Get on my schedule for a free no obligation call. Talkto a real food truck owner with decades of experience.  https://bit.ly/Bill-MooreLove what we do on the podcast? Show one time support here: https://bit.ly/Podcast-Support

Support the show: http://www.newcountry963.com/hawkeyeinthemorningSee omnystudio.com/listener for privacy information.

The weekend flew by as we return to the studio to give all of our thoughts on everything going on in the news. We chop it up about some of the sports we caught up on, the ongoing fallout from the murder of Charlie Kirk, and what ideas for school safety have come out of the recent trend of school safety trade conventions. Join us again for another great discussion of the current events!

In episode 1927, Jack and Miles are joined by author of Fetishized: A Reckoning with Yellow Fever, Feminism and Beauty, Kaila Yu, to discuss… Mike Johnson Walks Back Claim That Trump Helped The FBI Take Down Epstein, Eric Adams To Stay In Mayor’s Race... Until He Loses And Becomes A Saudi Ambassador, Women Are Going To Turkey For Limb Shortening Procedures? And more! Mike Johnson claimed Trump was anti-Epstein informant, then retreated amid criticism BREAKING: Mike Johnson just claimed that Trump “was an FBI informant” to help take down Jeffrey Epstein. New York City Mayor Eric Adams being eyed as Saudi ambassador: Reports Adams Insists He’s Running for Mayor Despite Saudi Ambassadorship Talks Women Are Going To Turkey For Limb Shortening Procedures? LISTEN: Victory Lap feat. Skepta, PlaqueBoyMax by Fred again..See omnystudio.com/listener for privacy information.

Mike Matthews investigates the fascinating news from the end of the week and Mike answers what is happening in the odd world of stupid ads. Join Mike as he podcasts live from Café Anyway in podCastro Valley with Madame Rootabega, Valentino, and Bison Bentley. Next show it's Chely Shoehart, Floyd the Floorman, and John Deer the Engineer.

Mike Matthews investigates the fascinating news from the end of the week and Mike answers what is happening in the odd world of stupid ads. Join Mike as he podcasts live from Café Anyway in podCastro Valley with Madame Rootabega, Valentino, and Bison Bentley. Next show it's Chely Shoehart, Floyd the Floorman, and John Deer the Engineer.

Mike Matthews investigates the fascinating news from the end of the week and Mike answers what is happening in the odd world of stupid ads. Join Mike as he podcasts live from Café Anyway in podCastro Valley with Madame Rootabega, Valentino, and Bison Bentley. Next show it's Chely Shoehart, Floyd the Floorman, and John Deer the Engineer.Become a supporter of this podcast: https://www.spreaker.com/podcast/mike-s-daily-podcast--609595/support.

Mike Matthews investigates the fascinating news from the end of the week and Mike answers what is happening in the odd world of stupid ads. Join Mike as he podcasts live from Café Anyway in podCastro Valley with Madame Rootabega, Valentino, and Bison Bentley. Next show it's Chely Shoehart, Floyd the Floorman, and John Deer the Engineer.

Mike Matthews investigates the fascinating news from the end of the week and Mike answers what is happening in the odd world of stupid ads. Join Mike as he podcasts live from Café Anyway in podCastro Valley with Madame Rootabega, Valentino, and Bison Bentley. Next show it's Chely Shoehart, Floyd the Floorman, and John Deer the Engineer.Become a supporter of this podcast: https://www.spreaker.com/podcast/mike-s-daily-podcast--609595/support.

Starting a podcast is easy—but building one that shortens your sales cycle, drives high-ticket leads, and supports your business? That's a different game.In this episode, Katie sits down with Megan Dougherty of One Stone Creative to unpack the business strategy behind podcasting. They dive into podcast value math, why most shows fail to convert, and how to create episodes that become evergreen sales tools.What You'll Learn:How to design a podcast that fits your business goalsWhy 12-15 focused episodes might be more powerful than 100 inconsistent onesThe real KPIs that drive ROI (hint: it's not downloads)When (and how) to turn your podcast into a strategic referral engineTimestamps:00:00 Introduction and Podcasting Strategy Overview01:08 Guest Introduction: Megan Doherty02:06 Common Misconceptions About Podcasting03:47 Designing a Podcast for Business Outcomes05:10 Shortening the Sales Cycle with Podcasts08:05 Entertainment vs. Business Podcasts09:56 Measuring Podcast Success13:54 Business Podcast Blueprints and State of Business Podcasting Report21:07 Final Thoughts and Contact InformationWant to create a podcast that does more than entertain? Visit podcastingforbusiness.com for Megan's full blueprint. DM Katie on LinkedIn if you want help bringing your podcast strategy to life.Visit Megan Dougherty online:Website: http://podcastingforbusiness.com/LinkedIn: https://www.linkedin.com/in/doughertymegan/Podcast: https://podcasts.apple.com/us/podcast/the-business-podcast-spotlight/id1801282981Learn more about Katie and Next Step Social Communications:Speaking: https://katiebrinkley.com/Website: https://yournextstep.agency/Linkedin: https://www.linkedin.com/in/katiebrinkleyYouTube: https://www.youtube.com/channel/@rockymountainmarketingInstagram: https://www.instagram.com/iamkatiebrinkley/Facebook: https://www.facebook.com/groups/socialprofitlab Hosted on Acast. See acast.com/privacy for more information.

Shortening your work week can actually increase productivity. Here's how. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Arizona Cardinals are in town to face the Broncos in a shared practice today ahead of the second preseason game on Saturday. Why are the Broncos preseason opponents the 49ers, Cardinals and Saints? Colorado native Trey McBride is one of the best tight ends in the NFL. Where does he rank among best football players to come out of the box state? Bo Nix and Courtland Sutton on their head coach. Browns star Myles Garrett was cited for speeding again, going 100 MPH in a 60 MPH zone. And what does it say about Sean Payton that he is simplifying and shortening his play calls so they are easier to understand? Catch a Thursday edition of Hot Takes with Eric Goodman and Bruce Haertl!

Trump is playing the ultimatum game with Russia. Shortening their 50-day warning to 10 to stop the war in Ukraine. Russia responded swiftly and said this new ultimatum is seen as a direct threat and a step towards war. 00:00 Backfire 07:35 Flash Update 10:09 Trump & Russia 16:17 Israel 21:26 Our Sponsors

Trump is playing the ultimatum game with Russia. Shortening their 50-day warning to 10 to stop the war in Ukraine. Russia responded swiftly and said this new ultimatum is seen as a direct threat and a step towards war. 00:00 Backfire 07:35 Flash Update 10:09 Trump & Russia 16:17 Israel 21:26 Our Sponsors

AP Washington correspondent Sagar Meghani reports on President Trump's new deadline for Russia to agree on ending the war in Ukraine.

In this diverse episode of China Manufacturing Decoded, hosts Adrian and Renaud cover several thought-provoking topics based on listeners' questions. They will discuss: How to transform an initial idea into a market-ready product. Cultural differences in business practices between Chinese and Western companies. Shortening manufacturing timelines, such as how to effectively reduce lead times. The differences between small and large-scale manufacturing.   Show Sections 00:56 – Listener Questions Format & First Topic Intro 01:13 – 1. Can You Sell Just an Idea or Invention? 09:43 – 2. Cultural Differences in Business Relationships (China vs. West) 16:19 – 3. How to Reduce Manufacturing Timelines? 24:29 – 4. Small vs. Large-Scale Manufacturing: Key Differences 30:25 – Wrap Up & Resources   Related content... 3 blog posts that contain a lot of advice about the common killers for hardware startups: The Market Technical Mistakes Running out of Funding "Flash of Genius" Movie Hofstede's cultural dimensions theory “The Culture Map” by Erin Meyer   Get in touch with us Connect with us on LinkedIn Contact us via Sofeast's contact page Subscribe to our YouTube channel Prefer Facebook? Check us out on FB Get in touch with us Connect with us on LinkedIn Contact us via Sofeast's contact page Subscribe to our YouTube channel Prefer Facebook? Check us out on FB

Massive earthquakes in Russia… The Earth spinning faster than ever recorded… Peace deals, Red Heifers, and rising global chaos. Is it climate change—or prophecy? Jesus told us in Matthew 24 that these signs would come like labor pains, signaling His soon return. The earth is shaking, the days are accelerating, and the Great Tribulation is drawing near. On today's episode of The Endtime Show, we'll break down the headlines, unpack the Scriptures, and explain why the world feels like it's convulsing—and what it all means for those who are watching, praying, and enduring to the end. 📱: It's never been easier to understand. Stream Only Source Network and access exclusive content: https://watch.osn.tv/browse 📚: Check out Jerusalem Prophecy College Online for less than $60 per course: https://jerusalemprophecycollege.com Learn more about your ad choices. Visit megaphone.fm/adchoices

When it comes to medical science, there's never been a better time to be alive than now… other than maybe a few months ago before the new Trump administration. Americans today are living longer than ever before, and that's owed in no small part to the National Institutes of Health—a government organization that has been responsible for some of the most significant biomedical advancements in the history of healthcare. Unfortunately, the Trump administration just virtually annihilated the NIH, and sentient gob of clay and anti-vax charlatan RFK Jr. is now in charge of the future of American health. To figure how how to navigate this insane dichotomy of medical potential and squandered medical possibility, Adam speaks with Dr. Eric Topol, a cardiologist and scientist, and director of the Scripps Research Translational Institute. Dr. Topol's book, Super Agers: An Evidence-Based Approach to Longevity, explores the cutting edge advancements in living longer, healthier lives—advancements which are now in jeopardy. Find Dr. Topol's book at factuallypod.com/books--SUPPORT THE SHOW ON PATREON: https://www.patreon.com/adamconoverSEE ADAM ON TOUR: https://www.adamconover.net/tourdates/SUBSCRIBE to and RATE Factually! on:» Apple Podcasts: https://podcasts.apple.com/us/podcast/factually-with-adam-conover/id1463460577» Spotify: https://open.spotify.com/show/0fK8WJw4ffMc2NWydBlDyJAbout Headgum: Headgum is an LA & NY-based podcast network creating premium podcasts with the funniest, most engaging voices in comedy to achieve one goal: Making our audience and ourselves laugh. Listen to our shows at https://www.headgum.com.» SUBSCRIBE to Headgum: https://www.youtube.com/c/HeadGum?sub_confirmation=1» FOLLOW us on Twitter: http://twitter.com/headgum» FOLLOW us on Instagram: https://instagram.com/headgum/» FOLLOW us on TikTok: https://www.tiktok.com/@headgum» Advertise on Factually! via Gumball.fmSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

BUFFALO, NY — June 25, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 5, on May 28, 2025, titled “Investigating telomere length in progeroid syndromes: implications for aging disorders.” In this study, led by first author Luma Srour and corresponding authors Yosra Bejaoui and Nady El Hajj, from Hamad Bin Khalifa University, Qatar Foundation, researchers investigated whether shortened telomeres, a marker of cellular aging, are present across various rare genetic disorders that mimic early aging, known as progeroid syndromes. The study found that telomere shortening, also called telomere attrition, is not a shared characteristic of all these disorders. This finding is important because it challenges the belief that telomere loss is a common thread in premature aging and could help refine how these syndromes are studied and treated. Progeroid syndromes are rare conditions that cause individuals to display symptoms of aging far earlier than expected. While some of these syndromes share signs of typical aging, others arise from very different genetic alterations. Researchers focused on comparing telomere length in individuals with several of these syndromes to better understand how aging develops at the cellular level. Telomeres are protective ends of chromosomes that shorten as cells divide, acting as a biological clock linked to aging and disease. Using DNA methylation data from blood samples, the team analyzed telomere length in patients with six progeroid syndromes: Werner Syndrome, Hutchinson-Gilford Progeria Syndrome, Berardinelli-Seip Congenital Lipodystrophy type 2, Dyskeratosis Congenita, Cerebroretinal Microangiopathy with Calcifications and Cysts, and Wiedemann-Rautenstrauch Syndrome. They found significant telomere shortening only in classical Werner Syndrome, Berardinelli-Seip Congenital Lipodystrophy type 2, and Dyskeratosis Congenita. Other syndromes, including the widely studied Hutchinson-Gilford Progeria Syndrome, did not show this pattern. “To investigate whether progeroid syndromes have telomere attrition, we calculated telomere length using the DNAmAge web-based calculator.” The findings suggest that telomere shortening cannot be used as a universal marker for all forms of premature aging. In fact, some syndromes linked to DNA repair problems showed telomere damage, while others with different genetic mutations did not. These results indicate that the underlying biology of each syndrome is crucial in determining whether telomere shortening plays a role. Researchers also compared telomere lengths in people with genetic variants known to protect against age-related diseases. Those with protective genes had longer telomeres than people with progeroid syndromes. This study challenges assumptions about aging in rare disorders and highlights the need for more personalized approaches in aging research. By identifying which syndromes involve telomere attrition, it opens new avenues for treating or delaying aging-related symptoms. Future research may explore other biological factors behind premature aging and how genetic differences influence the aging process. DOI - https://doi.org/10.18632/aging.206255 Corresponding authors - Yosra Bejaoui - yob4003@qatar-med.cornell.edu, and Nady El Hajj - nelhajj@hbku.edu.qa Video short - https://www.youtube.com/watch?v=T8vjIuYHaFg To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

In which we discuss which puzzles from the games we would want in an app!

06-18-25 - John Spent Day Delivering Water To Those In Need w/PHX Rescue Mission And Was Blown Away - UA Addressing Need For Med Professionals By Shortening Requirements For DegreeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

06-18-25 - John Spent Day Delivering Water To Those In Need w/PHX Rescue Mission And Was Blown Away - UA Addressing Need For Med Professionals By Shortening Requirements For DegreeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mike Johnson, Beau Morgan, and Ali Mac recap and react to the Atlanta Braves coming back from a 4-1 deficit yesterday to beat the New York Mets 5-4 in 10 innings last night in game one of their three game series. Mike, Beau, and Ali also explain why Spencer Schwellenbach going seven innings last night and shortening the bullpen was key to the Braves' win.

In our last episode of the series, we'll break down one of the most overlooked yet essential aspects of modern strategic planning: employee goal setting. Using the metaphor of a relay race, we'll explore how employees (your organization's sprinters) carry the baton of strategy across the finish line. But what happens when their efforts aren't aligned with departmental or strategic goals? Let's unpack why employee goals often get siloed in HR systems and investigate integrating them fully into your strategic framework.We'll look at best practices for setting clear, measurable, and motivating goals and emphasize the value of autonomy in unleashing employee innovation. From Google's 20% Rule to project sprint timelines inspired by Kickstarter, this episode offers actionable ways to transform your goal-setting process into a dynamic, participatory engine for progress. Whether you're a leader looking to engage your team or an employee seeking clarity and impact, this episode charts the path from fragmented efforts to unified, strategy-driven action.Show ReferencesStrickler, Y. (2011, June 17). Shortening the maximum project length [Blog post]. Kickstarter. https://www.kickstarter.com/blog/shortening-the-maximum-project-lengthSound Effect by Jerome ChauvelSound Effect by freesound_communityMusic by Dvir SilverstoneMusic by Joel FazhariMusic by Melody Ayres-GriffithsMusic by SoundUniverseStudio

Get my new book: https://bronsonequity.com/fireyourselfDownload my new special report - How to Use Inflation to Your Advantage - www.bronsonequity.com/inflationWelcome to our latest episode!Join host Bronson Hill and co-host Nate Hambrick for an inspiring June 2025 episode featuring Dr. Benjamin Hardy, organizational psychologist and bestselling author of 10X Is Easier Than 2X, The Gap and the Gain, and Who Not How. Dive into Hardy's forthcoming book, The Science of Scaling, and discover how to achieve bold goals by redefining time, raising your baseline, and embracing humility. From overcoming a traumatic childhood and a church mission to landing a $220,000 book deal, Hardy reveals how envisioning a bold future self shapes present actions, why 10-year goals can hinder progress, and how to reverse-engineer transformative results in three years or less.Perfect for investors and entrepreneurs, Hardy's strategies on filtering the present, building key partnerships, and letting go of outdated beliefs will empower you to redefine success.TIMESTAMPS00:48 - Guest introduction: Dr. Benjamin Hardy02:44 - Hardy's journey: From trauma to bestselling author06:39 - The Gap and the Gain: Balancing contentment and drive08:20 - Psychological time: Future shapes the present11:38 - Dopamine and ambition: Choosing the right goals14:03 - Resolving the past vs. creating a bigger future18:36 - Evolving as an author: Embracing changing views23:32 - The Science of Scaling: Raising your floor27:43 - Shortening timelines: 10-year goals in 3 years34:34 - Pathways to 10X: Acquisitions and efficiency39:48 - Humility in leadership: Stepping aside for scale45:10 - Power of partnerships: Distribution and capability51:47 - How to connect with BenConnect with the Guest:Website: www.scaling.comLinkedIn: https://www.linkedin.com/in/drbenjaminhardy/#10XGrowth #MindsetMatters #TheScienceOfScaling #FutureSelf #PersonalDevelopment #BusinessStrategy #HumilityInLeadership

Cavs need all they can do make it through shortening championship window full 775 Mon, 19 May 2025 13:55:00 +0000 v4WQK0oThyWVSjwpejOZdhpJMcX6Ojnr nba,cleveland cavaliers,sports The Ken Carman Show with Anthony Lima nba,cleveland cavaliers,sports Cavs need all they can do make it through shortening championship window The only place to talk about the Cleveland sports scene is with Ken Carman and Anthony Lima. The two guide listeners through the ups and downs of being a fan of the Browns, Cavaliers, Guardians and Ohio State Buckeyes in Northeast Ohio. They'll help you stay informed with breaking news, game coverage, and interviews with top personalities.Catch The Ken Carman Show with Anthony Lima live Monday through Friday (6 a.m. - 10 a.m ET) on 92.3 The Fan, the exclusive audio home of the Browns, or on the Audacy app. For more, follow the show on X @KenCarmanShow. 2024 © 2021 Audacy, Inc. Sports False https://player.amper

We get it. It's tempting to ask the people closest to us (and sometimes strangers on the internet) what we should do… for every single decision we have to make. But is this really what's best for us?On this week's episode, we're discussing the drawbacks of outsourcing our power to other people. Why do we trust everyone else on the planet more than we trust ourselves? How can we learn to listen to our own intuition, sort through advice from other people, and take actions that move us towards the life we desire?The truth is that other people are only able to tell you how they see it. Their perspective is clouded by their own life experiences and circumstances, and those oftentimes don't align with our own. If you're looking to stop wasting time asking other people for advice and are ready to start taking action moving towards the one you desire, press play. Our perspective may be just the thing you need to get started.Takeaways:The societal norm encourages seeking validation from others.Listening to oneself is often overlooked in favor of external advice.The cost of ignoring self-trust can be significant.Quiet reflection is necessary to hear our inner voice.Pleasing everyone is impossible and can lead to dissatisfaction.Trusting ourselves can enhance our relationships with others.Self-trust is a lifelong journey that can start at any moment.Chapters:11:00 Navigating External Advice vs. Internal Wisdom21:40 Building Trust in Ourselves23:05 A Pivotal Moment: Learning to Trust Yourself31:06 Navigating Health and Self-Care34:03 The Importance of Quiet and Reflection37:17 Shortening the Gap Between Knowing and DoingLove,Meg & MaggiFollow us:⁠Instagram⁠⁠TikTok⁠⁠Facebook⁠⁠Youtube ⁠[self-trust, personal growth, decision making, advice, inner voice, self-awareness, mental health, Glennon Doyle, Untamed, personal development]Music curtesy of LiQWYD

What's going to make your marketing stand out as everything gets louder and more automated? In today's episode, I'm diving into my predictions for where things are headed—and what you really need to focus on if you want to stand out. From the growing importance of messaging and creativity to the role AI is starting to play in shaping content, I'm sharing what we're seeing on the front lines with clients and inside my own team. Plus, we'll talk about why polarizing content matters more than ever and how to meet your audience exactly where they're at. If you're ready to stay ahead of the curve, this episode is for you.

Tiffany, Mike and Beau react to the latest news out of the NFL owners' meetings

Which is more worrisome: How much each hot dog you eat shortens your life or the fact that Slacker didn't know they were called "glizzies"?

Full show - Thursday | GMD - Minivan or SUV? | News or Nope - Gene Hackman | Erin has a stash of embarrassing pictures of Slacker | Worth it | Do you know if you were breastfed? | T. Hack's controversial Slackerism rankings | Glizzies are shortening your life | Stupid stories @theslackershow @thackiswack @radioerin

In this episode, David Sandstrom discusses the critical importance of social relationships and their impact on health. He emphasizes that loneliness and social isolation can be as harmful as smoking, sedentary lifestyle, or obesity. Drawing from scientific studies and biblical teachings, he highlights the necessity of fostering loving relationships and offers practical tips for improving relational connectedness. The episode concludes with a call to action for listeners to prioritize their relationships and consider joining a new community focused on natural health. Time Stamps: Chapters 00:00 Introduction and My New Online Membership Community 01:56 The Impact of Social Relationships on Health 07:46 Understanding Loneliness and Social Isolation 10:37 Benefits of Relational Connectedness 12:34 Practical Tips for Fostering Healthy Relationships 15:27 Conclusion and Next Steps Links: Full Show Notes Page More episodes: Podcast Hompage For a Copy of David's Book: The Christian's Guide to Holistic Health Ask David a question to be answered on an upcoming episode: Ask Me Anything Would you like to be on the Show? Schedule a Lifestyle Audit Twitter X Youtube

Adam Silver floated the idea of shortening NBA games. Is this actually a good idea? What will this trade deadline look like? Evan gives his top 5 teams that need to make a trade. Also, what will the Rams do with Matt Stafford in 2025? Plus, what are the Browns going to do with Myles Garrett? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Adam Silver floated the idea of shortening NBA games. Is this actually a good idea? What will this trade deadline look like? Evan gives his top 5 teams that need to make a trade. Also, what will the Rams do with Matt Stafford in 2025? Plus, what are the Browns going to do with Myles Garrett? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Adam Silver floated the idea of shortening NBA games. Is this actually a good idea? What will this trade deadline look like? Evan gives his top 5 teams that need to make a trade. Also, what will the Rams do with Matt Stafford in 2025? Plus, what are the Browns going to do with Myles Garrett? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Adam Silver floated the idea of shortening NBA games. Is this actually a good idea? What will this trade deadline look like? Evan gives his top 5 teams that need to make a trade. Also, what will the Rams do with Matt Stafford in 2025? Plus, what are the Browns going to do with Myles Garrett? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Adam Silver floated the idea of shortening NBA games. Is this actually a good idea? What will this trade deadline look like? Evan gives his top 5 teams that need to make a trade. Also, what will the Rams do with Matt Stafford in 2025? Plus, what are the Browns going to do with Myles Garrett? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Welcome to a new episode of Business Lunch! In this episode, Roland Frasier and Ryan Deiss discuss Elon Musk's unique approach to problem-solving, where he reportedly solves his companies' biggest problems in a matter of weeks. They analyze the pros and cons of Musk's leadership style, including his willingness to make tough decisions and the potential impact on employees. The hosts also explore whether this approach can be replicated by other business leaders.Highlights:"He just came in there and went just ape, you know, and kind of gutted everybody who was essentially middle management.""The fundamental job, the single most important job that any CEO has, is determining what is the company's right next thing.""I do love the idea of saying, like, we are going to solve this problem in weeks, to say that every single thing that is our biggest problem can always be solved in a singular week.""If you're a leader, and if you decide that you're going to take on the role of solving a particular problem in your team, I don't think that's necessarily a bad thing, because, frankly, your people probably are above full capacity already."Timestamps:00:00 - Elon Musk's Approach to Problem-Solving01:20 - Musk's Ability to Solve Problems Quickly03:08 - Identifying the Real Problem07:03 - Feasibility of Musk's Approach09:01 -Downsides of Musk's "Demon Mode"12:38 - The CEO's Role in Determining the Right Next Thing13:40 - Shortening the Unit of Measurement15:00 - Empowering Middle Management20:00 - Communicating the Problem-Solving Approach26:35 - The Sustainability of Elon Musk's ApproachCONNECT • Ask Roland a question HERE.RESOURCES:• 7 Steps to Scalable workbook • Get my book, Zero Down, FREETo learn more about Roland Frasier