Podcasts about kunz

Mona Kuhn discusses her recent artistic shift towards multimedia projects, specifically her "Kings Road" series. She explains that after years of focusing on traditional photography and print making, she felt the need to explore new avenues post-pandemic. This led her to create a 12-minute film composed of still photographs that are projected onto multiple walls, creating an immersive experience. The project, which also incorporates an original score by her husband, a composer, traveled extensively to various museums, including the Arts Design and Architecture Museum in Santa Barbara, the Kunz house, and a museum in China. Kuhn highlights how the addition of music influences the viewer's experience, impacting their pace and emotional connection to the work. The projections were shown alongside her traditional prints in a separate room, emphasizing the scale and cinematic nature of the multimedia installation.Show Clip from The Paris Chong Show with Mona Kuhnhttps://youtu.be/0hOYuPcKGVkhttps://www.theparischongshow.com

In March 1998, Father Alfred Kunz was murdered inside St. Michael Catholic Church in Dane, Wisconsin. Many believe he was murdered because he had knowledge of sexual misconduct within the church, while others say he was murdered because of allegedly inappropriate relationships with female parishioners. Join Mike and Gibby as they discuss the murder of Father Alfred Kunz. There have been no shortages of suspects in this case over the years. But, one by one, the police have ruled people out using DNA found at the crime scene. The theories in the case range from greed, inappropriate relationships, to the possibility that Kunz was about to go public with a list of priests who had committed sexual offenses.You can help support the show at patreon.com/truecrimeallthetimeVisit the show's website at truecrimeallthetime.com for contact, merchandise, and donation informationAn Emash Digital productionSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Wie entstehen Wellen im Meer? Über diese Fragen spricht Ole im Kinderpodcast „Ole schaut hin“ mit Meeresbiologe, Taucher und Moderator Uli Kunz.

Hey ihr pixelverliebten Ketchupköpfe mit Doku-Faible!

Wenn du Ausschreibungen erstellst oder prüfst, solltest du diese Folge nicht verpassen – sie kann dir viel Ärger und noch mehr Kosten ersparen. Schlechte Ausschreibungen kosten Bauherren und Unternehmer nämlich jedes Jahr Millionen. In dieser Folge decken wir die häufigsten Fehler auf – und zeigen, wie du mit einer präzisen Ausschreibung bis zu 7 % der Baukosten sparen kannst!   Martin Kunz erklärt, was in den meisten Ausschreibungen fehlt, welche Unterlagen wirklich nötig sind und warum eine saubere Planung schon Monate vor dem Baustart beginnt. Du lernst, wie du teure Nachträge vermeidest, rechtssicher ausschreibst und mit der richtigen Terminstrategie bessere Angebote erhältst.   Pflichtwissen für Planer, Architekten und Bauleiter – wie immer praxisnah, klar und mit echten Erfahrungswerten.   Mehr Infos und Kontakt: www.kunz-bauloesungen.ch  Vernetze dich mit Martin Kunz auf LinkedIn   Weitere Podcastfolgen und Blogartikel findest du unter: www.marcofehr.ch/mehr    Abonniere, sonst gibt‘s Bauschäden ╔═╦╗╔╦╗╔═╦═╦╦╦╦╗╔═╗ ║╚╣║║║╚╣╚╣╔╣╔╣║╚╣═╣  ╠╗║╚╝║║╠╗║╚╣║║║║║═╣ ╚═╩══╩═╩═╩═╩╝╚╩═╩═╝   Für weitere Fragen kontaktiere bitte diese Adresse: redaktion@marcofehr.ch --------------------------------------------------------------- Folge mir auf diesen Kanälen für mehr Bauqualität und Kosteneinsparung • LinkedIn - https://www.linkedin.com/in/marco-fehr/  • Facebook -  https://www.facebook.com/marco.fehr.12  • Twitter - https://twitter.com/MarcoFehr_  • Tiktok - https://www.tiktok.com/@bauherren_podcastschweiz  • Instagram - https://www.instagram.com/marco.fehr_/  • Blog - https://marcofehr.ch/baublog/  • Spotify - https://open.spotify.com/show/2XPzukLLm2EGVxpVwMoiys  • YouTube - https://www.youtube.com/@bauherrenpodcastschweiz  • iTunes - https://podcasts.apple.com/ch/podcast/bauherren-podcast-schweiz/id1485359745  • LinkedIn Bauexperten Gruppe - https://www.linkedin.com/groups/13832518/  • Marketing-Akademie für Bauexperten - https://baufachwissen-akademie.ch/course/baufachwissen-marketing  

Der Teilhaber stürzt aus dem 10. Stock – und der Chef ist verschwunden! Im Bauunternehmen «Kunz AG» geht es drunter und drüber. Madeleine arbeitet dort als Sekretärin – und stösst auf lauter Ungereimtheiten im Todesfall. Dabei deckt sie auch ziemliche dubiose Geschäftspraktiken auf ... (00:00) Beginn Episode (02:39) Beginn Hörspiel (51:49) Gespräch ____________________ Die handelnden Figuren: · Manfred Kunz – Chef der Firma «Kunz AG», Bauunternehmer auf der Sonnenseite des Lebens · Peter Lüthi – Teilhaber der «Kunz AG», Chefingenieur, Bauunternehmer auf der Schattenseite des Lebens · Urs von Bergen – junger, aufstrebender, noch recht neuer Mitarbeiter bei Kunz, Ingenieur und Bauführer · Madeleine Habegger – Sekretärin von Kunz · Annemarie – Sekretärin von Lüthi und (später) beste Freundin von Madeleine · Alexander Pavlicek – Architekt beim Architekturbüro «Sterli und Hirth», beauftragt von Kunz · Arnold Mosimann – Banker · Giovanni di Pietro – Vorarbeiter · Werner Schlegel – Kondukteur in der Geisterbahn & Komplize ____________________ Mit: Franz Matter (Kunz), Birgit Steinegger (Frau Kunz), Yvonne Roth (Madeleine), Peter Wyss (Lüthi), Dori Grob (Annemarie), Peter Holliger (von Bergen), Dieter Stoll (Pavlicek), Paul-Felix Binz (Mosimann), Rainer Zur Linde (Schlegel), Eleonore Bürcher (Frau Dufaud), Peter Freiburghaus (Giovanni), Liselotte Favri (Serviertochter), Max Begert (Polizist), Daniel Kasztura(Polizist), Kurt Frauchiger (Polizist), Hans-Rudolf Spühler (Polizist), Hanspeter Otti (Hausmeister), Erwin Leimbacher (Kellner), Rolf Schwab (Kondukteur), Charlotte Acklin (Barmaid), Charles Benoit (Taxifahrer), Max Füri (Autofahrer, Telefonstimme) ____________________ Tontechnik: Werner Feldmann – Regie: Charles Benoît ____________________ Produktion: SRF 1980 ____________________ Das andere Hörspiel mit Madeleine als Ermittlerin könnt Ihr hier nachhören: https://www.srf.ch/audio/krimi/1-2-draeckegi-woesch-gespraech?id=54108079-cf03-45be-9c89-da400a9824af https://www.srf.ch/audio/krimi/2-2-draeckegi-woesch-gespraech?id=69bdc6c9-9e91-4a64-aa93-35110d790f9e Das Theaterstück von Markus Keller und Rusudani Tabukaschwili läuft momentan in Bern: https://www.theater-effinger.ch/premieren/eine-besondere-strasse

Ingenieur Lüthi stürzt zu Tode – auf der Baustelle seines Unternehmens. Alles sieht nach einem Unfall aus. Doch seine Sekretärin Madeleine bekommt einen Verdacht: War es Selbstmord? Oder sogar ... Mord! Wunderbar lebensnaher Krimi aus der Schweiz. (00:00) Beginn Episode (02:58) Beginn Hörspiel (47:04) Gespräch ____________________ Die handelnden Figuren: · Manfred Kunz – Chef der Firma «Kunz AG», Bauunternehmer auf der Sonnenseite des Lebens · Peter Lüthi – Teilhaber der «Kunz AG», Chefingenieur, Bauunternehmer auf der Schattenseite des Lebens · Urs von Bergen – junger, aufstrebender, noch recht neuer Mitarbeiter bei Kunz, Ingenieur und Bauführer · Madeleine Habegger – Sekretärin von Kunz · Annemarie – Sekretärin von Lüthi und (später) beste Freundin von Madeleine · Alexander Pavlicek – Architekt beim Architekturbüro «Sterli und Hirth», beauftragt von Kunz · Arnold Mosimann – Banker · Giovanni di Pietro – Vorarbeiter ____________________ Mit: Franz Matter (Kunz), Birgit Steinegger (Frau Kunz), Yvonne Roth (Madeleine), Peter Wyss (Lüthi), Dori Grob (Annemarie), Peter Holliger (von Bergen), Dieter Stoll (Pavlicek), Paul-Felix Binz (Mosimann), Rainer Zur Linde (Schlegel), Eleonore Bürcher (Frau Dufaud), Peter Freiburghaus (Giovanni), Liselotte Favri (Serviertochter), Max Begert (Polizist), Daniel Kasztura(Polizist), Kurt Frauchiger (Polizist), Hans-Rudolf Spühler (Polizist), Hanspeter Otti (Hausmeister), Erwin Leimbacher (Kellner), Rolf Schwab (Kondukteur), Charlotte Acklin (Barmaid), Charles Benoit (Taxifahrer), Max Füri (Autofahrer, Telefonstimme) ____________________ Tontechnik: Werner Feldmann – Regie: Charles Benoît ____________________ Produktion: SRF 1980 ____________________ Das andere Hörspiel mit Madeleine als Ermittlerin könnt Ihr hier nachhören: https://www.srf.ch/audio/krimi/1-2-draeckegi-woesch-gespraech?id=54108079-cf03-45be-9c89-da400a9824af https://www.srf.ch/audio/krimi/2-2-draeckegi-woesch-gespraech?id=69bdc6c9-9e91-4a64-aa93-35110d790f9e Das Theaterstück von Markus Keller und Rusudani Tabukaschwili läuft momentan in Bern: https://www.theater-effinger.ch/premieren/eine-besondere-strasse

Hey ihr Zeitreisenden mit Wurstverstand und Erinnerungslücken!

Wie erleben Jugendliche ihre ersten Schritte in die Berufswelt? In dieser Folge begleiten wir Lernerinnen und Lerner des Leifheit-Campus, die im Mai ihr Praktikum absolvierten – unter anderem bei der Stiftung Scheuern und der Kita im Mühlbachtal. Wir haben mit der Berufswahlkoordinatorin Désirée Kunz über die Ziele der Praktikumswoche gesprochen, lassen die Jugendlichen selbst zu Wort kommen und haben bei der Kitaleitung Ramona Lau nachgefragt, wie es ist, Praktikant*innen zu begleiten. Ein Einblick in Erwartungen, Erfahrungen und das, was ein gutes Praktikum wirklich ausmacht. Jetzt reinhören!

Gm! This week we're joined by Sergej Kunz to discuss 1inch's recent launch on Solana. We deep dive into building on the EVM vs SVM, 1inch's path forward, powering cross chain liquidity, how to improve execution & more. Enjoy! -- Follow Sergej: https://x.com/deacix Follow Jack: https://x.com/whosknave Follow Lightspeed: https://twitter.com/Lightspeedpodhq Subscribe to the Lightspeed Newsletter: https://blockworks.co/newsletter/lightspeed -- Grab your tickets to Permissionless IV. Use code LIGHTSPEED10 for 10% off: https://blockworks.co/event/permissionless-iv -- Get top market insights and the latest in crypto news. Subscribe to Blockworks Daily Newsletter: https://blockworks.co/newsletter/ -- Zenrock is a permissionless, decentralized custody network backed by 1RoundTable Partners, 10T, Maven11, and Spartan. Live on Jupiter, $ROCK is the native token for transactions within the Zenrock ecosystem and secures Zenrock's decentralized custody network. The first application launching on Zenrock is zenBTC – yield-bearing Bitcoin on Solana. zenBTC will be live in April 2025. Visit zenbtc.io to learn about earning yield with Bitcoin on Solana. -- (00:00) Introduction (01:24) Launching 1inch On Solana (08:15) Zenrock Ad (08:58) Execution On Solana (17:42) Building On The EVM vs SVM (20:58) Sandwich Attacks (28:17) Zenrock Ad (29:00) Building A DEX Aggregator Business (35:55) The Path Forward For 1inch (36:57) Cross Chain Liquidity (43:23) What's Next For 1inch? -- Disclaimers: Lightspeed was kickstarted by a grant from the Solana Foundation. Nothing said on Lightspeed is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Mert, Jack, and our guests may hold positions in the companies, funds, or projects discussed.

In dieser Folge von „Mensch, Meike!“ wird's richtig lustig – denn kein Geringerer als die hessische Comedy-Legende Peter Kunz ist zu Gast bei Meike Buschening-Kaffenberger! Peter plaudert mit Meike über seine Anfänge auf der Bühne, gibt Nachhilfe im hessischen Dialekt – und sorgt natürlich für jede Menge Lacher. Außerdem verrät Stand-up Comedian Peter Kunz, wie seine Comedy-Programme entstehen. Aktuell ist er noch bis zum 5. Juli mit seinem Programm „Akzeptanz durch Penetranz“ unterwegs – und ab September geht's dann weiter mit dem neuen Solo-Programm „Hesskalation“. Den nächsten Live-Auftritt von Comedian Peter Kunz könnt ihr am 17. Mai in Mühlheim am Main erleben. Mehr über Peter Kunz, den hessischen Humor und seine kommenden Shows erfahrt ihr in dieser Folge von „Mensch, Meike!“. Viele Spaß bei Zuhören!

Cult thinking. Groupthink. Black and white thinking. “Loud, vocal thinkers' and how extreme sound bites dominate the modern media landscape thanks to algorithms, painting a ‘majority picture' when most people are not living out those extremes in day-to-day lives.It's quite a time to be alive, and also a time when it's very easy to let the fear of something cloud our ability to judge the reality of a situation fully. Is “Apatheism” a new way forward? I've always been fascinated by people we turn into our saviours and gurus, as well as charismatic authoritarians who sweep in and seduce us in our personal or collective vulnerable times.. That moment we start rationalising and making excuses for a cult leader, where perhaps a couple of years ago, we'd have been dead against that very thing/person we now defend.On Monday, I explore the murky waters of freedom, autonomy, cults and social systems with Professor of Political Science and Constitutional Law, Adam Scott Kunz, who specialises in cults and political philosophy and has worked alongside the famed Dr Janja Lalich, considered a global authority on cults, until her recent retirement.This show is NOT an attack on anyone, your beliefs, your religion, the diet you feel healthiest on or other held views, but a show to see how we can ensure we are “critical thinking” and not just believing we are, and how we can balance beliefs with values with freedom and come together on common overlaps that benefit us all and how we all struggle with freedom and belonging and ‘others'. One thing I know for sure after this conversation is that the best thing is to know we don't know anything for sure. So there you go! I hope you tune into this fascinating exploration… Alexx xWant to learn more about this week's guest? Website: www.adamkunz.com Thank you to this month's show partners for joining us to help you make your low tox swaps! @ausclimate is our major partner giving you 10% off their range for 2025, with Winix Air Purifiers, Dehumidifiers and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimate@ediblebeautyau has put together a generous offer for us - 30% off for the month of May with code: LOWTOXLIFE. Seriously. Why not indulge yourself in the ultimate low tox facial, for some self-pampering this month?!Be sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs.Want to support the Low Tox Life podcast?Free option: Leave a 5 star review wherever you listen to Low Tox Life - thanks SO much!Paid + Member PERKS: Join the Low Tox Club - monthly practitioner live masterclasses, a suite of low tox store discounts from around the world and the most supportive and lovely chat group on all low tox topics on the internet: Check it out and join here for just the price of a coffee per month! Hosted on Acast. See acast.com/privacy for more information.

Hey, ihr Flachland-Philosophen und Geburtstags-Nachfeierer!

Danielle Kunz Dwyer, founder of Yoga For You, talks with J about organizing a business and being together in a more expansive state. They discuss connecting via email and open sourcing info on how to go online, studying Ayurveda and yoga in NYC in the early aughts, periods of unknowing, unwinding of identity, students and subscriptions, honoring yourself and valuing teachers, opening a center and pandemic policies, profitability of the yoga profession, foundations of trust, and what really grows someone in their practice.   To subscribe and support the show… GET PREMIUM. Say thank you - buy J a coffee. Check out J's other podcast… J. BROWN YOGA THOUGHTS.    

Karen Conti chats with Dr. Adam Kunz, assistant professor at University of Wisconsin-Eau Claire, about the First Amendment and if it allows cult organizations to brainwash people. Dr. Kunz also talks about what can be done legally to extricate cult members from those organizations.

In der aktuellen Folge von Wirtschaft Düsseldorf Unplugged spricht Moderatorin Andrea Greuner mit Alesia Kunz, Gründerin von LearnSlice – einem bootstrapped Unternehmen aus Düsseldorf, das Firmen dabei hilft, Talente zu gewinnen, langfristig zu binden und wertvolles Wissen effizient zu sichern.  

Hey, ihr Serienjunkies, Tagebuchpoeten und Klangfetischisten!

About the series: It's not just a relationship, a purchase, or a decision. It's a path. Every path has a destination. In the end, we will end up at the destination from the path we have chosen to take. With driving or hiking, getting lost will cost us minutes or hours. With life, it will cost us years!   About this week's message: We are surrounded with advertisements calling out to us to purchase their product. The ads use subtle hooks to lure people to buy. Hooks such as, “You need this!” “Everyone has this!” “Don't think, just buy it!” Too many people are living in financial bondage as a result. They unknowingly walked a path that led them to ruin and destruction.   Key Phrase: “Be very careful, then, how you live – not unwise but as wise.”Ephesians 5:15

The great Swiss city of Zurich is one of the more picturesque, pixel-burning European gateway destinations. Within minutes of exiting Zurich Airport, armed with my trusty Eurail Pass, I was blissfully whizzing into the city centre on a 10 minute train ride. Strolling across the cobbles of this time-honoured city in the crisp spring air, there's so much urban eye-candy to lift the spirit. I sized up the largest clock face in Europe, on the edge of the Limmat River. It's bigger than Big Ben. Riding the skyline, the historic tower of St Peter Church is imbued with a trusty timepiece, as are the oh-so punctual church bells that loudly reverberate across the Old Town from the four historic churches, including mighty Grossmunster Cathedral. No wonder everything runs to time in Switzerland. According to legend, Zurich's 13th-century landmark cathedral was founded by Charlemagne, built on the graves of the city's patron saints, Felix and Regula. It was also the starting place of the Protestant Reformation in Zurich. Culture is writ large in Zurich's Old Town, where the narrow-cobbled streets gave rise to the Dada art movement just over a century ago. I popped into Cabaret Voltaire, at Spiegelgasse 1, which was the birthplace of Dada and the avant-garde artistic movement in 1916. Absinthe is the drink of choice here, among Dada's ghosts. Strolling along Bahnhofstrasse, flanked by chic designer boutiques and swanky department stores, Café Sprungli deserves a pit-stop. This prized Zurich institution is rightly lauded for its heavenly macaroons and hand-crafted chocolates. They are like exquisite works of art – as were the Easter chocolate displays. It's like a bespoke art gallery in chocolate. Don't mind if I do. Further down the street, if feeling a little decadent, make a date with Teuscher for its famed champagne truffles. In a city of water and stone bridges, a top vantage point to survey the elemental landscape, above the twisting lanes of the Old Town, is the Lindenhof. This was the site of a former Roman customs house and fourth-century fort, perched above the water. Alongside soaking up the city vistas, this elevated park with its Linden trees and giant chess sets is the pitch-perfect spot for a cheeky picnic. The vast assortment of guildhalls is core to Zurich's backstory, and they're great fun to explore. In 1336, Zurich's first independent mayor, Rudolf Brun, established the guild laws, effectively shifting power from the abbeys to the merchant nobility. The handsome guildhalls, with all their intricate decorative features, lend themselves to a leisurely inspection. I started at the bakers' guild, in Oberdorfstrasse, before heading over the river's east bank to Niederdorf, to admire the guilds of the carpenters, builders, the food and wine dealers, the textiles and spice merchants, all along Limmatquai. Then, on Munsterhof, you've got mansions of the weavers, saddlemakers, painters and winemakers. In German-speaking Zurich, the street food tradition of wurst remains wildly popular – particularly for lunch. In the Old Town, tuck into some great sausage at Wursteria by Hinz and Kunz. This part-butcher shop and part deli serves up super spicy bratwurst in a fluffy bun. So good! As its name suggests, Cafe Conditorei 1842, on Napfgasse, is an old-school establishment, chock-full of sweet indulgence. Spanning four floors, food lovers can enjoy patisserie, cakes and hot drinking chocolate – they claim to be Zurich's best. On the ground floor of this historic confectioner's store, impressively decorated in neo-baroque style, you'll struggle to find a finer array of patisserie, cakes and tarts. I could have stayed there all day. And yes – the steaming mug of hot chocolate with whipped cream was magnificent. Speaking of chocolate, the Lindt and Sprungli factory has called Zurich home, since 1899. Seven years in the making, Lindt Home of Chocolate, was designed to complement the historic building and serve as a beacon to chocolate lovers everywhere. From cultivation to production, the interactive museum does a sterling job telling the story of Swiss chocolate making, not only about Lindt, but its predecessors. While the maze of white, milk, and dark chocolates is impressive, the Lindt Home of Chocolate also boasts another record: the world's largest chocolate fountain. Standing at about 30 feet tall, even Willy Wonka would be impressed by this show-stopper. Zurich is home to FIFA's world headquarters and in a bid to stop pesky football fans from loitering in the lobby, the FIFA Museum was created nine years ago, in the heart of town. Spread over three floors and loaded with interactive exhibitions, the FIFA Museum examines all aspects of the global game and how it passionately stirs people's emotions. Football is the great equaliser. Along with the original FIFA World Cup Trophy, the museum displays over 1,000 items of exclusive memorabilia and apparel, including the national shirts of all FIFA member associations. The original trophy, which features a gold statuette of Nike, the Greek goddess of victory, holding a cup, was permanently awarded to Brazil after they won the cup for the third time, in 1970. The current trophy contains 5kg of pure gold and its estimated value is over NZ$30m. A highlight amongst the interactive games gallery is the gigantic pinball machine, where you can test your own ball kicking skills. With the next World Cup just a year away and featuring the All Whites for just the third time, add this museum to your check-list. Creating quite a buzz in recent years, Zurich-West has been spectacularly transformed from a once scruffy industrial district. Emerging as a vibrant cultural quarter of trendy eateries and edgy art, factories have been repurposed as theatres and shipyards reimagined as art galleries. Viadukt is an exemplary example of the makeover, with a host of eateries, pop-up shops and art spaces housed inside the arches of the disused, 550-feet long railway viaduct. You'll also find Prime Tower here, a 35-storey skyscraper (Switzerland's tallest), serving up a panoramic treat across Zurich's rooftops, gleaming lake and snow-coated peaks beyond. Take in the sweeping scenery over a drink or two at Clouds Bar – and salute your return to Europe. The locals are very proud of the city's brilliant and bizarre festivals. In August Zurich hosts Street Parade, one of Europe's biggest celebrations of peace, love and electronic music, attended by millions of people. In a couple of weeks, the city grinds to a halt for Seschselauten. This annual April spectacle involves setting on fire a giant straw snowman called the Boogg. The time it takes for the Boogg's head to explode indicates whether it will be a good summer, apparently. The word is Zurich is in for a long, warm summer. Perfectly poised overlooking Paradeplatz, the city's most prestigious address, the Mandarin Oriental Savoy Hotel offers a stylish stay to remember, when in Zurich. Just steps from the city's iconic shopping sweep of Bahnhofstrasse, it's been just over a year since the Mandarin Oriental revitalised what has been Zurich's oldest grand hotel, reaching back to 1838. Elegantly and artfully refreshed, with a boutique hotel vibe, the 80 impeccably redesigned rooms and suites raise the bar on luxury and indulgence. There's four distinctive dining venues including the Michelin-starred Orsini, where the Italian fine dining experience is helmed by acclaimed two-Michelin starred Italian Consultant Chef Antonio Guida. Then there's 1838, the effervescent rooftop bar with its spell-binding panoramic vistas of the city, lake and serrated Swiss Alps. Plus Savoy Brasserie & Bar is a sure-bet for a stupendous breakfast, with an delightfully presented buffet selection, in addition to a la carte menu items. Accommodations take their design cues from the natural palette of Zurich, headlined by the artisanal hand-painted silk wallpapers, inspired by the aqua green and blue hues of the lake and sky, to the mist of the surrounding mountains. Meticulously crafted design elements and materials adorn the rooms. Accents of colour are also reflected in custom furniture and carpets. Principal materials include walnut as a common thread, touches of bronze and brass and enamelled lava together with the comfort of luxurious textiles. Throughout the hotel, I loved admiring the multitude of sculptural lighting fixtures and lamps. I stayed in the Munsterhof Suite, accentuating the sumptuous sense of comfort, glamour and space, loaded with indulgent touches. There's a personal cocktail bar, built-in headboards, sublime marble-clad bathrooms and expansive walk-in dressing areas. As is the case with all Mandarin Oriental properties, you'll soon get a sense of the strong local connection the hotel has with the city. Local artists are proudly showcased with numerous pieces of art to admire, throughout the hotel. Grab a peek at the storied meeting room on the second floor, which is still home to the Guild of Tanners and Shoemakers. These traditional Swiss craftsmen have been meeting here for over a century. Service personifies whip-smart Swiss efficiency and the charismatic staff are highly personable, outgoing and engaging. You'll struggle to find fault with this gorgeous hotel which has mastered the art of fusing contemporary comforts with timeless opulence and celebrating a deep respect for history, tradition and proud sense of place. www.mandarinoriental.com Grab a ticket to ride on the European railway network with a Eurail Pass. For over 65 years, Eurail Passes have enabled flexible borderless rail travel across Europe. 7000 Kiwis purchased such a pass last year, which gives you access to 30,000 destinations across 33 countries, allowing you to chart your own amazing rail adventure. On popular rail routes, it certainly pays to make a seat reservation in advance. Lock in your rail plans ahead of your trip, by booking tickets or a rail pass to suit with Eurail direct. The mobile pass is the way to go. The Eurail app is easy to navigate, packed with helpful information and benefits, network disruption notifications, and enabling you to check timetables, lock in bookings and seat reservations on the go, via your mobile. www.eurail.com Fly to Zurich with Cathay Pacific who operate ultra-contemporary A350-1000s, from Auckland via Hong Kong. The cabin air quality is decidedly better, the aircraft are noticeably quieter and I experienced minimal jet-lag. The extensive CX Entertainment system kept me suitably engaged with excellent movie and box-set selections, live news channels - all in vivid 4K, plus in-flight WiFi is available. www.cathaypacific.com Mike Yardley is our resident traveller and can be heard every Saturday with Jack Tame on Newstalk ZB. LISTEN ABOVE See omnystudio.com/listener for privacy information.

Hey, ihr Kaffee-Connaisseure und April-Scherz-Gegner! ☕

Zum Leben gehört es, zu gewinnen UND zu verlieren, zu lachen UND zu weinen und eben auch über manche Dinge hinweg zu sehen. Die Fälle, über die Nicole und Angi in dieser Folge sprechen, sind so bunt wie die Welt und das ist gut so. Mehr Infos zu Nicole Staudinger findet Ihr unter www.nicolestaudinger.de

W piątek w "Onet Rano." gośćmi Łukasza Kadziewicza będą: Anna Cichowska, mentorka zmiany i rozwoju kariery; Paweł Kunz, dziennikarz; kuqe 2115, wokalista; Dorota Gardias, dziennikarka; Bartas Szymoniak, wokalista. W części "Onet Rano. WIEM" gościem Odety Moro będzie Agnieszka Beczek, tanatokosmetolog.

Viele Jahre führten Sacha und Brigitte Kunz ihre eigene Imbissbude beim Kutterhafen von Dorum-Neufeld an der Nordseeküste. Aus gesundheitlichen Gründen musste Sacha Kunz jedoch seinen Küsten-Imbiss schweren Herzens aufgeben. Doch er hat schon wieder neue Pläne. Familie Kunz lebt in der kleinen und beschaulichen Ortschaft Dorum an der Nordsee. Der Norden von Deutschland, hat ihnen schon immer gefallen, sagt Sacha Kunz: «Wir haben viele Jahre Ferien an der Nordseeküste verbracht und haben uns in die Gegend verliebt. Die traumhafte Landschaft, die Leute und die frische Luft sind einmalig. Wir wussten, da gehören wir hin!» 2019 machte Familie Kunz ihren Traum wahr und wanderte von Läufelfingen (BL) an die Nordsee aus. Sie eröffneten ihren eigenen Küsten-Imbiss auf der Hafenplattform in Dorum-Neufeld und verkauften Currywurst mit Pommes mit Blick aufs Meer. Die Urlauber und Einheimischen standen nicht nur wegen den leckeren Würsten Schlange, sondern auch wegen der herzlichen Gastfreundlichkeit der Schweizer: «Wir mögen es mit Leuten zu schwatzen, auch wenn die Arbeit schweisstreibend war.» Sacha Kunz musste aus gesundheitlichen Gründen seinen Imbiss letztes Jahr abgeben. Doch das hält ihn nicht davon ab, neue Pläne zu schmieden. «Wir sehen uns Morgen in aller Frische!» Unter diesem Motto führten Sacha und Brigitte Kunz sechs Jahre lang erfolgreich ihren Küsten-Imbiss in der Nähe des Kutterhafens Dorum-Neufeld. «In aller Frische» zeigt sich Sacha Kunz nun mit seinem Mini-Imbisswagen auf vier Rädern. Eine Attraktion in der Gegend. Regelmässig wird er für kleinere und grössere Anlässe gebucht: «Man kann mich mieten zum Beispiel für Geburtstage.»

Want to fall in love with your ADHD brain and make it work for you? Learn more about my patented program, Your ADHD Brain is A-OK Academy here: programs.tracyotsuka.com/signup__Growing up as the youngest of ten kids, Chelsea Kunz learned early how to be loud, funny, and grab attention—which, as it turns out, is pretty on-brand for an ADHD brain. Now an actor, creator, and self-described hot mess mom, Chelsea built an online following as Karen Disapproves, blending comedy and chaos into relatable parenting content. But behind the laughs, she's been on a deep dive into self-development, spirituality, and purpose, which led her to launch the Soul Slumber Party podcast.In this conversation, Chelsea shares her ADHD diagnosis journey, from being the class clown (and occasional teacher's nightmare) to struggling with focus, working memory, and traditional academics. She opens up about how ADHD showed up in motherhood, why she felt overwhelmed and irritable after having kids, and what finally led her to seek a diagnosis. Tracy and Chelsea also talk about nervous system regulation, how overstimulation can lead to emotional dysregulation, and why finding the right creative outlet can make all the difference for ADHD brains.Chelsea also breaks down how she balances big ideas, creative projects, and intuitive decision-making, from social media to screenwriting. If you've ever felt like you're juggling too much or struggling to follow through on what matters most, this conversation will leave you laughing, nodding along, and maybe even rethinking how you approach your creativity.Resources:Instagram: https://www.instagram.com/soulslumberparty YouTube: https://www.youtube.com/@soulslumberparty TikTok: https://www.tiktok.com/@soulslumberparty Send a Message: Your Name | Email | Message Learn more by connecting with Tracy through Instagram, Facebook, LinkedIn, Pinterest, or visit adhdforsmartwomen.com.Are You Ready to Discover Your Brilliance? Order Now: https://adhdforsmartwomen.com/bookJoin Your ADHD Brain is A-OK: https://adhdforsmartwomen.com/aokVisit our website: https://adhdforsmartwomen.comJoin our community of ADHD For Smart Ass Women: https://www.facebook.com/groups/tracyotsuka Join What Do I Do With My Life Masterclass: spyhappy.me/classUnlock your best days with Blends: https://adhdforsmartwomen.com/blends

In this episode, artist Rebecca Lee Kunz takes us behind the scenes of her Caldecott Medal winning book, CHOOCH HELPED (written by Andrea L. Rogers

On March 4th 1998 Father Alfred Kunz was found brutally murdered in the one place he should've felt the safest. Listen in as we deep dive into a tale full of twists, turns and whacky characters. Watch this episode on YouTube: YouTube.com/@cultliterCall the Hotline: 747-322-0273Buy my book: prh.com/obitchuaryMerch! Merch! Merch!: wonderyshop.com/cultliterCome see me on tour: obitchuarypodcast.com Write me: spencer@cultliter.comSpencer Henry PO Box 18149 Long Beach CA 90807 Follow along online: instagram.com/cultliterpodcast instagram.com/spencerhenryJoin our patreon: Patreon.com/cultliterCheck out my other show OBITCHUARY wherever you're listening now! Sources: https://news.google.com/newspapers?id=pytFAAAAIBAJ&sjid=XbsMAAAAIBAJ&pg=3019,1276199&dq=alfred-kunz+dane&hl=enhttps://en.wikipedia.org/wiki/Murder_of_Alfred_Kunzhttps://captimes.com/news/local/crime_and_courts/to-catch-a-cold/article_d974937f-f98a-55a1-a41d-aa7a6d55a6c4.htmlhttps://chucknowlen.com/kunz.htmhttps://s3.documentcloud.org/documents/5691267/Chapter-one-documents.pdfhttps://s3.documentcloud.org/documents/5684948/Kunz-Homicide-Report.pdfhttps://www.catholicworldreport.com/2018/08/08/the-unsolved-murder-of-fr-alfred-kunz/https://www.catholicworldreport.com/2018/08/15/i-dont-know-if-they-will-ever-reveal-why-he-was-murdered/https://www.catholicworldreport.com/2018/08/22/detectives-hope-trail-wont-go-cold-in-priests-murder-probe/https://projects.jsonline.com/topics/unsolved/season-three/chapter-2-instruct-the-ignorant.htmlhttps://projects.jsonline.com/topics/unsolved/season-three/the-devil-you-know.htmlhttps://s3.documentcloud.org/documents/5684950/Cavanaugh-Criminal-Complaint.pdfhttps://s3.documentcloud.org/documents/5684951/Death-Investigation-March-25-1998.pdfhttps://s3.documentcloud.org/documents/5684952/Updated-Homicide-Report-Dec-17-2000.pdfhttps://www.chicagotribune.com/2005/02/06/some-call-him-priest-church-calls-him-fake/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I can't imagine hosting a podcast about grief and not having a conversation about suffering and how we understand its role and impact in our lives.Today's episode is a nod to my 16 year old self, who having experienced some life changing events already, craved conversations that could help me make sense of the suffering I had witnessed.With me today to dive deep, is my friend Tamal. He is a mentor, storyteller, social-philosopher, retreat-leader and ceremonialist. He is also a painter, dancer, hermit and preposterous clown.Tamal has been studying and teaching ancestral wisdom traditions for 27 years. Among other things, he was a monk for 11 years based in India, and trained in shamanism in Peru for 4 years after that. His summary conclusion about life is that the task is to transform our paradigm of duality into one of polarity. A fundamental part of this process is a re-orientation toward suffering.We discuss his perspective on why looking directly at our own suffering, as well as that of those around us—in our homes, communities, and globally—can help us become more loving, beautiful, and potent in our service and our callings.Imagine what can shift in our lives when we allow ourselves to be honest about the effects of our suffering, name our confusion and doubt, and dive deep beneath the surface to connect to sacred wisdom.If you are someone who has wrestled with your own faith while suffering, no matter the framework of belief you come from, I believe this conversation will encourage you in your deeper exploration.Push play, share and subscribe (of course)!Also, thank you for supporting the show!-RachelWhere to Find Tamal:Moonshine Mundali CommunityInstagram: @Tamal.Kunj

Send us a textWelcome to the Via Stoica Podcast, the Podcast on Stoicism.Join us for an insightful conversation with Meredith Alexander Kunz, co-author of "Beyond Stoicism" alongside Massimo Pigliucci and Gregory Lopez. In this episode, we explore the intersection of Stoic philosophy and modern parenting, the vital role of women in Stoicism, and examine the current state of Stoic practice. Meredith shares her unique perspective on applying ancient wisdom to contemporary challenges, particularly in family life and personal development.Meredith Alexander Kunz is a Silicon Valley-based writer, communications leader, and Stoic philosophy practitioner who bridges the gap between ancient wisdom and modern living. Known online as "The Stoic Mom," she brings a fresh perspective to practical philosophy while balancing her roles as a mother of two daughters and an accomplished academic. With degrees from Harvard College and Stanford University, Meredith's work spans both technical and philosophical realms – from science and technology communications to exploring how Stoic principles can enhance parenting and personal growth.As a personal and professional development coach grounded in Stoic principles, Meredith helps clients navigate life's challenges with practical wisdom. Her writing has appeared in prestigious publications including Newsweek, The San Francisco Chronicle, and Stanford Business. Through her popular blog "The Stoic Mom" (now on Substack) and social media presence, she continues to build a community around mindful parenting and practical philosophy.Find Meredith's insights and join her philosophical journey on social media platforms @thestoicmom, where she regularly shares wisdom on applying Stoic principles to modern family life and personal development.Read our comprehensive book review on Beyond Stoicism here: https://viastoica.com/beyond-stoicism/Don't forget to subscribe to the Via Stoica Podcast wherever you get your podcasts and leave us a rating to help more people discover these valuable conversations about practical philosophy and modern Stoicism. Your support helps us continue bringing you thoughtful discussions with leading voices in the Stoic community.Support the showwww.ViaStoica.comhttps://viastoica.com/stoic-life-coaching/https://viastoica.com/benny-voncken/https://viastoica.com/Brendan-hogle/https://viastoica.com/Brice-noble/https://twitter.com/ViaStoicaReach us: info@viastoica.comProduced by: http://podmedia.net/

In this solo episode, Chelsea Kunz talks about her personal journey with self-love, authenticity, and embracing her inner magic. Chelsea explores candid topics such as overcoming self-doubt, redefining self-love, and identifying limiting beliefs. She shares profound insights gained from sleepless nights, group meditations, and even quirky experiments with AI. Tune in for heartfelt advice, practical exercises, and Chelsea's unique, humorous perspective on unlocking the divine creator within us all. Soul Slumber Party Soul Slumber Party InstagramSoul Slumber Party TikTok Soul Slumber Party FacebookShow Inquiries soulslumberpartypod@gmail.com

Dr. Shaalan Beg and Dr. David Wang discuss key abstracts in GI cancers from the 2025 ASCO Gastrointestinal Cancers Symposium, including major advances in CRC, neoadjuvant approaches in esophageal cancer, and innovative studies on ctDNA. TRANSCRIPT Dr. Shaalan Beg: Hello and welcome to the ASCO Daily News Podcast. I'm Dr. Shaalan Beg. I'm a medical oncologist and an adjunct associate professor at UT Southwestern Medical Center in Dallas. Today, we're bringing you some key highlights from the 2025 ASCO Gastrointestinal Cancers Symposium, and I'm delighted to be joined by the chair of GI25, Dr. David Wang. Dr. Wang is a GI medical oncologist at the University of Michigan. Our full disclosures are available in the transcript of this episode.  Dr. Wang, thanks for coming on the podcast today. Dr. David Wang: Well, thank you. It's a pleasure to be here. Dr. Shaalan Beg: GI25 featured major therapeutic advances across the spectrum of GI malignancies, and it was exciting to hear about innovations and novel approaches that are shaping the future of our field. Before we start talking about specific abstracts, could you share some of your key highlights from the meeting? Dr. David Wang: Sure. Our theme this year was “Breaking Boundaries to Enhance Patient Centered Care.” Past years' themes have focused more on precision oncology, but we wanted to broaden our focus on patients and to be more holistic, which kind of led us into some of the Intersection [sessions] that we had. Each day started with a different Intersection. The first one was “Emerging Therapies in GI Cancers”, where invited speakers talked about bispecific antibody drug conjugates, theranostics, CAR T and other cell-based therapies. The second day was on “Personalized Risk Assessment for GI Cancers,” and this included looking at polygenic risk scores for colorectal cancer, microRNAs and liquid biopsies such as exosomes and pancreatic cancer and non-endoscopic screening modalities in esophageal cancer. And on our final day, we wanted to talk about “Integrative Oncology and Integrative Medicine,” looking at evidence-based uses of acupuncture and supplements in patients who are receiving treatment for cancer, mindfulness-based practices and exercise. And of course, we had a fantastic keynote talk by Dr. Pamela Kunz from the Yale School of Medicine titled, “Disrupting Gastrointestinal Oncology: Shattering Barriers with Inclusive Science.” She highlighted the intersection of science, patient care, and health and gender equity. And I would encourage your podcast listeners to access the lecture in ASCO's Meeting Library if they haven't yet had a chance to hear Dr. Kunz's wonderful lecture.  We were really happy this year because the attendance hit a new record. We had over 5,000 people attend either in person or virtually from their home or office, and we had almost 1,000 abstracts submitted to the meeting, so these were either record or near record numbers. We offered a lot of different networking opportunities throughout the meeting, and attending found these to be incredibly rewarding and important and this will continue to be an area of emphasis in future meetings. Dr. Shaalan Beg: Let's take a deeper dive into the exciting studies presented at GI25. The late breaking abstract LBA143 was CheckMate-8HW. This was the first results of NIVO + IPI versus NIVO monotherapy for MSI-high metastatic colorectal cancer. What are your thoughts about this study? Dr. David Wang: Yeah, so we know that colorectal cancer patients with MSI-high tumors don't necessarily respond well to chemotherapy. And we were fortunate because last year CheckMate-8HW actually looked at two different arms – so this was NIVO + IPI compared to standard of care chemotherapy and showed its very significant improvement in median progression-free survival. And that was actually published in the New England Journal of Medicine back in November of 2024. This year's presentation actually focused now on NIVO + IPI versus NIVO monotherapy. And as you know IPI+NIVO can be quite toxic. So this was an important analysis to be done. So we know that NIVO is definitely more easily tolerated. So what was interesting was that the 2-year and 3-year progression-free survival not surprisingly favored IPI+NIVO and this was statistically significant. And the overall response rate was also better with IPI+NIVO versus NIVO alone. I know we're always concerned about toxicities and there were higher grade 3 and 4 toxicity incidences in the combination arm versus the monotherapy arm, but overall, only about 28 additional events in several hundred patients treated. So I think that's well-tolerated. Our discussant Dr. Wells Messersmith actually said that, with this new data, he would consider doing combination immunotherapy in any patient that presented in the front line with MSI-high or deficient mismatch repair colorectal cancer that was metastatic. Dr. Shaalan Beg: One of the focuses for directing first-line therapy for colorectal cancer has been right and left sided colon cancer because we know these are two different cancers with their own unique molecular subtypes. We heard on Abstract 17, the DEEPER trial, the final analysis of modified FOLFOXIRI plus cetuximab versus bevacizumab for RAS wild-type and left sided metastatic colorectal cancer. How do you summarize the findings of this study and what should our readers be aware of? Dr. David Wang: Interestingly, this was a phase 2 study and the emphasis of the abstract was actually a subgroup analysis of those patients with RAS wild-type and BRAF wild-type as well as left sided cancers. So, I think the entire study enrolled 359 patients, but the analysis that was discussed at the meeting really focused on 178 patients that fit that characteristic. Very similar to what we've seen in prior studies, left-sided tumors have better response to cetuximab versus bevacizumab. And if you flip it so that you now are looking at right sided tumors, targeting EGFR is actually detrimental. The depth of response was better with cetuximab in these left sided RAS and BRAF mutant tumors. And so the lead author actually suggested that this could be a new first-line standard of care. And the question is, is there a benefit of doing this triple agent regimen with modified FOLFIRINOX? We know there's a lot more toxicity with that. Not clear that there's a benefit for that over FOLFOX, maybe in younger patients that could tolerate it. When our discussant, again Dr. Wells Messersmith, spoke about this, he said that, in his practice he would, again, favor cetuximab over bevacizumab in combination with chemo, these left-sided RAS and BRAF wild-type tumors, but that he would actually prefer a doublet versus a triplet chemo regimen, and that is consistent with the current NCCN guidelines. Dr. Shaalan Beg: Another area where colorectal cancer has been a wonderful model to study new technology has been in the area of circulating tumor DNA (ctDNA). And the BESPOKE CRC trial is looking to see if ctDNA can inform adjuvant treatment decisions for stage II and III colorectal cancer. And in Abstract 15, we heard final results of the BESPOKE CRC sub-cohort. What were the findings there? Dr. David Wang: BESPOKE CRC is another one of these important ctDNA studies. It was an observational study, not a randomized trial, but it did provide a lot of different insights to us. We know that there were over 1,700 patients enrolled, and so it was reported that this is the largest ctDNA study in colorectal cancer performed in the United States. And they were able to analyze over 1,100 patients.  Some of the key findings were that postoperative adjuvant therapy management decisions actually changed in 1 out of 6 patients, so that's pretty significant. In terms of surveillance, we know that patients who have ctDNA positivity, this is prognostic of recurrence. In terms of patients who have positive ctDNA post-surgery, it looked like, at least in this observational study, the majority of patients who received any benefit were those who had positive ctDNA. So adjuvant therapy, even in stage II and stage III patients seemed to only benefit those patients who have positive ctDNA. I think that does raise the question, and this also was brought up in the discussion, which is “Can we de-escalate adjuvant therapy in terms of patients who are ctDNA-negative post-op?” And Dr. Richard Kim from Moffitt felt that we are not yet there. Obviously, we need randomized control trials where we are taking ctDNA results and then randomizing patients to receive adjuvant or non-adjuvant to really know the difference.  Other questions that come up with use of ctDNA include: What do you do with these patients who turn positive? This study for BESPOKE actually followed patients out to two years after surgery. So what you do with a positive ctDNA result wasn't really clear. It seems to suggest that once you turn positive, patients go on to more intensive surveillance. You know, again as an observation, patients who did turn positive were able to go to metastasis-directed therapy much more quickly. And again, this was supposedly to improve their curative intent therapy. And I think the other question that has been brought up all the time is, is this really cost effective? Patients want to know, and we want to give patients that information, but I think we're still stuck with what to do with a positive ctDNA level in a patient that's on surveillance because no randomized control studies have actually suggested that we need to start systemic therapy right away. Dr. Shaalan Beg: Yeah. And I guess in terms of practice informing or practice changing, these results may not give us a clear answer. But because a lot of patients are asking for these tests, it does give us some real world experiences on what to expect in terms of conversion of these positive into negative and the outcome so we can have a shared decision making with our patients in the clinic and then come up with a determination on whether ctDNA for molecular residual disease is something which would be worthwhile for the care of our patient. But more to come, I guess, in coming years to answer different problems around this challenge. Dr. David Wang: Yes, I agree. Dr. Shaalan Beg: The BREAKWATER trial looked at the use of encorafenib, cetuximab and chemotherapy for BRAF V600E-mutant metastatic colorectal cancer. We've covered this combination for a second- third-line treatment in metastatic colorectal cancer previously. Abstract 16 from GI25 was evaluating the use of this regimen in the first-line space. Everyone was looking forward to these results, and what did the investigators present? Dr. David Wang: I think this is, as you mentioned, a nice follow up to later lines of therapy where Dr. Kopetz from MD Anderson pioneered use of encorafenib, cetuximab and binimetinib in the BEACON trial. Everybody was kind of curious what would happen now if you use encorafenib plus cetuximab plus chemotherapy in the first-line setting. And so this is an interim analysis that was pre-planned in the phase 3 open label BREAKWATER trial. And even though there were three arms, and so the three arms were encorafenib plus cetuximab, encorafenib plus cetuximab plus FOLFOX, or standard of care chemo, only two arms were presented in the abstract. So basically looking at encorafenib plus cetuximab and FOLFOX-6 versus standard of care therapy, and the overall response rate was statistically significant with a 60.9% overall response rate encorafenib plus cetuximab plus chemo arm versus standard of care chemo was only 40%. The interim overall survival also was different. It was 92% versus 87% at 6 months and 79% versus 66% at 12 months, again favoring the chemotherapy plus encorafenib plus cetuximab. In terms of the statistics, the p was 0.0004. However, the pre-plan analysis required the p-value to be 1x10 to the -8. And so even though this looks really good, it hasn't quite met its pre-specified significance level. The good thing is that this is only interim analysis and the study is ongoing with future analysis planned.  So the real question is: Does it matter when we actually use this regimen? We know that the regimen's approved in the second third-line setting. What about in the first line? And there was some preclinical data that the discussant reviewed that shows that patients actually benefit if this is done in the first-line setting. For example, there was some preclinical data showing that even FOLFIRI, for example, can upregulate RAS, which would make tumors more resistant to this combination. This was thought to be practice-changing in a patient that has B600E showing up treatment naive that we should probably consider this regimen. And actually this did receive accelerated FDA approval about a month ago. Dr. Shaalan Beg: Yeah, and for what it's worth, I put up a Twitter poll asking my Twitter followers on how the BREAKWATER trial results will change their approach for newly diagnosed BRAF mutated colorectal cancer. We got 112 responses; 72% said that they will incorporate encorafenib, cetuximab, FOLFOX for their frontline BRAF mutated patients. But 23% said that they would like to wait for overall survival results. Dr. David Wang: Wow, that's interesting. They really want that 1x10 to the -8. Dr. Shaalan Beg: I guess so. All right. Let's change gears and talk about esophageal cancer. LBA329 was the SCIENCE study which presented preliminary results from a randomized phase 3 trial comparing sintilimab and chemoradiotherapy plus sintilimab versus chemoradiotherapy for neoadjuvant resectable locally advanced squamous esophageal cancer. Where are we in this space? Dr. David Wang: Okay. So, yeah, this was an interesting trial. Again, just to set the context, esophageal squamous cell carcinoma is more prevalent in Asia. And the study sites as well as the patients were mostly from Asia. So this was again a phase 3 trial with interim results. They only rolled 146 out of the planned 420 for this interim analysis. And yeah, they're using immune checkpoint inhibitor that we don't use in the United States, sintilimab, combined with their two standards of neoadjuvant therapy, either chemotherapy, which is more common in Asia, or or chemoradiation, which is more common in the US and Western Europe, versus chemoradiation. And so they actually had two primary endpoints, but only were reporting one. So their two primary endpoints were pathCR and the other one was event-free survival. The event-free survival, again, was not reported at the meeting.  What they found was that in terms of pathCR rate, if you take the two arms that are really informative about that, chemoradiation plus sintilimab versus chemoradiation alone, the pathCR rate was 60% versus 47%. We know that chemo alone doesn't induce as much of a pathCR rate, and that was 13%. So it was found that the delta in terms of pathCR between the chemoradiation arms, one with sintilimab and one without, was significant. And this actually confirms data again from Asia, like for the ESCORT-NEO trial where it used another immune checkpoint inhibitor pembrolizumab in addition to neoadjuvant chemo.  So as our discussant for this abstract said, yes, we know that radiation combined with chemotherapy improves pathCR rates, but we have recent data from the ESOPEC trial, we don't know that that necessarily will translate to overall survival. So again, waiting for additional enrollments and longer term follow up before incorporating this into clinical care here. Dr. Shaalan Beg: So David, how do the results of the SCIENCE trial compare with our practice in the United States and ongoing studies asking questions for neoadjuvant therapy for esophageal carcinoma in the United States? Dr. David Wang: I think obviously immune checkpoint inhibitor in the new adjuvant setting is important. Jennifer Eads at UPenn is running that EA2174 which is looking at chemoradiation plus or minus nivolumab, and then in non-pathCR responders randomized to adjuvant nivolumab per CheckMate 577 or nivolumab with intensification adding ipilimumab. We know that the ESOPEC trial just came out, and was published actually during the meeting, and that really focuses on adenocarcinomas. So adenocarcinomas of the GE junction, distal esophagus, now, we would probably treat very similarly to gastric using perioperative FLOT. However, the standard in the US for esophageal squamous cell carcinoma remains neoadjuvant chemoradiation. We know that squamous cell carcinomas are more exquisitely sensitive to radiotherapy. And then obviously in those patients who don't achieve a pathologic complete response, the expectation would be that they would go on to receive nivolumab per CheckMate 577. Again, the thought is that these tumors are more sensitive to immunotherapy given their higher incidences of mutational changes. And so again, this kind of goes along with the positive results seen in the SCIENCE trial that we just discussed with sintilimab but also EFFECT-neo with pembrolizumab. Obviously, we await the results of Jennifer's trial. Dr. Shaalan Beg: And the last abstract I was hoping we could get your perspective on was Abstract 652, which is a Phase 3 study of everolimus plus lanreotide versus everolimus monotherapy for unresectable or recurrent gastroenteropancreatic neuroendocrine tumors, the STARTER-NET trial. What were the results of this study? Dr. David Wang: So, I just want to give a shout out because we did have a session at this year's GI ASCO that looked at more rare tumors. So appendiceal tumors, neuroendocrine tumors, those kinds of things. So again, I would encourage your listeners to listen to that session if they have interest in that. Another type of rare tumor was adenosquamous tumors.  But in terms of the STARTER-NET trial, this was again an interim analysis of his phase 3trial and it was looking at combining everolimus plus lanreotide versus everolimus. So we know that in pancreatic-gastric neuroendocrine tumors, if you have low Ki-67, a well differentiated tumor, that the standard of care really is a somatostatin analog, and sometimes if they're more aggressive, we kind of consider molecular targeted therapy with everolimus. This was asking the question of whether we should do the combination on the frontline. And what was interesting is in this study, the patients were actually more of a poor prognostic set. So they had Ki-67 up to 20% or these were patients that actually had multiple liver lesions. And what they found was a median for progression free survival was improved with a combination out to 29.7 months versus 11.5 months with the somatostatin analog alone, and that the overall response rate was 23% versus 8.3%, again, favoring the combination. If you looked at subgroup analysis, it was actually those patients who had Ki-67 greater than 10%, so the more aggressive tumors, or those with diffuse liver lesions that had the most benefit. So I think that would be the patient population I would consider this new combination with using would be those patients again with poorer prognosis neuroendocrine tumor phenotype. Dr. Shaalan Beg: Thank you very much, Dr. Wang, for sharing your insights with us today and your great work to build a robust GI Cancers Symposium this year. Dr. David Wang: Well, thank you. I mean that really is a cooperative effort. We appreciate all the members of the GI25 Program Committee as well as the ASCO staff that just made it an outstanding meeting. Dr. Shaalan Beg: And thank you to all our listeners for your time today. You'll find links to the abstracts discussed today on the transcript of this episode.  Finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers:  Dr. Shaalan Beg @ShaalanBeg  Dr. David Wang Follow ASCO on social media:   @ASCO on Twitter  @ASCO on BlueSky ASCO on Facebook   ASCO on LinkedIn   Disclosures:  Dr. Shaalan Beg:  Employment: Science 37  Consulting or Advisory Role: Ipsen, Array BioPharma, AstraZeneca/MedImmune, Cancer Commons, Legend Biotech, Foundation Medicine  Research Funding (Inst.): Bristol-Myers Squibb, AstraZeneca/MedImmune, Merck Serono, Five Prime Therapeutics, MedImmune, Genentech, Immunesensor, Tolero Pharmaceuticals  Dr. David Wang: Honoraria:  Novartis Consulting or Advisory Role: Novartis, Cardinal Health, Bristol-Myers Squibb, BeiGene, Eisai  

Dior Kunz Jr., a two-year-old boy, went missing on July 10, 2015, during a camping trip at Timber Creek Campground in Idaho with his parents, Jessica Mitchell and Dior Kunz Sr., his great-grandfather Robert Walton, and a family friend, Isaac Reinwand. The parents reported leaving Dior with Walton briefly, but upon their return, he was gone, prompting an extensive search involving law enforcement, search dogs, helicopters, and volunteers. Despite thorough searches of the area, no evidence of Dior's whereabouts was found. Various theories, including accidental disappearance, animal attack, abduction, and foul play by those present, have been proposed, but no conclusive evidence has emerged. As of 2024, the case remains unsolved, with no new leads, leaving the mystery of Dior Kunz Jr.'s disappearance unresolved.Matthew Green, a 39-year-old math teacher and experienced outdoorsman, disappeared in July 2013 while on a solo hike near Mammoth Lakes, California. Despite extensive search efforts involving local authorities, volunteers, and advanced technology, no trace of him has ever been found. Matthew, who had a seizure disorder requiring daily medication, left his belongings at the campground, suggesting he intended only a short hike. His disappearance remains a mystery, with theories ranging from a medical emergency or hiking accident to more speculative ideas of foul play or voluntary disappearance. Over a decade later, his family continues to search for answers, utilizing newer search technology and maintaining hope for closure.to contact me:bobbycapucci@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

Dior Kunz Jr., a two-year-old boy, went missing on July 10, 2015, during a camping trip at Timber Creek Campground in Idaho with his parents, Jessica Mitchell and Dior Kunz Sr., his great-grandfather Robert Walton, and a family friend, Isaac Reinwand. The parents reported leaving Dior with Walton briefly, but upon their return, he was gone, prompting an extensive search involving law enforcement, search dogs, helicopters, and volunteers. Despite thorough searches of the area, no evidence of Dior's whereabouts was found. Various theories, including accidental disappearance, animal attack, abduction, and foul play by those present, have been proposed, but no conclusive evidence has emerged. As of 2024, the case remains unsolved, with no new leads, leaving the mystery of Dior Kunz Jr.'s disappearance unresolved.Matthew Green, a 39-year-old math teacher and experienced outdoorsman, disappeared in July 2013 while on a solo hike near Mammoth Lakes, California. Despite extensive search efforts involving local authorities, volunteers, and advanced technology, no trace of him has ever been found. Matthew, who had a seizure disorder requiring daily medication, left his belongings at the campground, suggesting he intended only a short hike. His disappearance remains a mystery, with theories ranging from a medical emergency or hiking accident to more speculative ideas of foul play or voluntary disappearance. Over a decade later, his family continues to search for answers, utilizing newer search technology and maintaining hope for closure. 10:09)to contact me:bobbycapucci@protonmail.com

Die Silvesternacht verlief in den beiden Basel ohne grössere Zwischenfälle. Die Notfallstationen in den Spitälern waren allerdings voll. Ausserdem: · Bar Hinz und Kunz muss schliessen · Amokdrohungen beschäftigen Schulen in der Region

Welcome back, beautiful souls!   In this new episode, I'm joined by the inspiring Chinyelu Kunz, founder of We Nurture Collective, to explore the magic and challenges of early childhood development. Together, we dive deep into the first seven years of a child's life and how we, as parents, can create a nurturing environment filled with unconditional love, structure, and understanding.   Chinyelu offers soulful and practical wisdom on creating consistent rhythms, addressing challenging behaviors with compassion, and guiding our little ones toward independence.   This episode is a must-listen for parents seeking to embrace the beautiful journey of raising their children with intention and grace.     About Chinyelu:   Chinyelu is the founder of We Nurture Collective, her online platform which includes her podcast episodes, instagram posts, Blog, parenting coaching support, and mentoring for early childhood educators and her newest offering - The Nurturing Circle her online community. She has worked as a Waldorf early childhood educator for over 25 years. Chinyelu completed her Waldorf Early Childhood teacher training and she also holds a Masters in Architecture as well as a Bachelors in Interior Architecture. Her mission is to make easily accessible knowledge, advice and guidance on parenting and caregiving in the early years through the lens of Waldorf Education. She is the proud mother of 3 Waldorf graduates.   Website / Social Media Handles: Connect@wenurturecollective.com     Ps: If you are ready to finally see how you can bring in thousands of dollars per week while just doing a few simple actions (and never feel like you *HAVE* to work an 8 hour day again)? To have clear direction in your day to day activities so you can easily implement strategies for more simplicity in your life and biz? Then 5 weeks to 5 figures course is for you! Check the link below

Chinyelu Kunz, author of The Little Book of Parenting, opens this episode with a deeply spiritual childhood experience in a time of war. From this spiritual place, Chinyelu offers us ideas on becoming a nurturing parent despite the obstacles in our own childhood experiences. She invites us to trust our children, especially when they don't conform to traditional learning benchmarks, and trust ourselves as we grow and change along with them. Find Chinyelu's book, podcast, and course offerings at the We Nuture Collective.#anthroposophy#waldorfearlychildhood#waldorfeducation#waldorfteacher#waldorfhomeschool#rudoflsteiner#wenuturehttps://wenurturecollective.com/

In the small rural town of Athens, Wisconsin, the Kunz family were known as strange loners at the center of decades worth of rumors. On July 4th, 1987 the entire family save for one member was murdered in their home, stirring up more rumors that still exist today. There was a conviction in relation to their deaths, but there is much speculation as to whether true justice was served.

Chelsea Kunz dives deep into the concept of winning and how it's definition varies person to person. Chelsea also discusses the inspiration she draws from watching the Mike Tyson and Jake Paul fight, relating it to personal growth and victory beyond just monetary gain. She explores the idea of doing just to remind ourselves we are brave, the importance of stepping out of comfort zones, the motivation behind creating, and how to escape creative inertia. Chelsea inspires listeners to rediscover their passions and pursue creative endeavors purely for the joy they bring, not just for societal notions of success.Soul Slumber Party Soul Slumber Party InstagramSoul Slumber Party TikTok Soul Slumber Party FacebookShow Inquiries soulslumberpartypod@gmail.com

In 2015, 2-year-old DeOrr Kunz went missing during a camping trip in Leadore, Idaho, leading to extensive but ultimately unsuccessful searches, and his parents being named as suspects without charges ever being filed. For full details on the disappearance of DeOrr Kunz, join Nancy tonight at 6 and 9 Eastern on Merit Street Media. Check your local listings for channel number. Or follow Crime Stories with Nancy Grace on your favorite podcast app. See omnystudio.com/listener for privacy information.

In the debut episode of Manufacturing the Workforce of Tomorrow, Toni Neary, Director of Community Engagement at SME, speaks with Jeannine Kunz, SME's Chief Workforce Development Officer, who has spent over 20 years advancing workforce strategies in manufacturing. Jeannine shares insights into SME's mission to equip the industry with both cutting-edge technology and skilled talent, emphasizing the critical connection between them. This episode explores SME's national initiative, the Manufacturing Imperative Workforce Pipeline Challenge, which unites community colleges across 17 states to bridge the skills gap. Jeannine discusses SME's commitment to optimizing, accelerating, and scaling workforce solutions that drive innovation, resilience, and competitiveness in manufacturing. Tune in to learn how SME is building a future-ready manufacturing workforce.

In this episode, Sergej Kunz, Co-Founder of 1inch Network, shares his journey into the crypto space and the development of 1inch. He discusses his background as a software engineer and his early interest in cryptocurrencies. Sergej talks about his experience participating in hackathons and how he and his co-founder, Anton, built the first version of 1inch in New York City. He also shares the story behind the name '1inch' and how they pitched the idea to investors. Sergej explains the concept of aggregation in the DeFi space and how 1inch aims to provide a more efficient trading experience for users. He also discusses the development of the 1inch wallet and the importance of owning the user's experience. In this conversation, Sergej also discusses the geoblocking of the 1inch platform in the US and the decision-making process behind it. He also talks about the 1inch wallet and card, which allow users to easily spend cryptocurrencies in real life. Sergej explains the launch of Fusion, a compliant institutional environment for interacting with DeFi liquidity, and the concept of intent-based protocols. He shares his vision for the future of 1inch, including the use of payment channels and the development of a decentralized API network. Sergej emphasizes the importance of decentralization and building something that is used by a large number of people.

Jason Kunz, a safety leader with over a decade at 3M, shares insights on building top-tier safety programs, preventing serious injuries, and how technology is reshaping safety. He also touches on worker engagement and a life-saving CPR experience. Tune in for practical tips to elevate your safety approach. Learn more about Jason at at ⁠⁠www.kunzCompany.com⁠⁠. Thanks to our sponsors: E-Tank, TerraTherm, Enthalpy Analytical, and Zappa Stewart

Inside the Issue: Optimizing the Diagnosis and Treatment of Neuroendocrine Tumors | Faculty Presentation 2: Later-Line Treatment for Advanced NETs — Pamela Kunz, MD CME information and select publications

Chelsea Kunz talks about how to raise your vibration both quickly and longterm. She also touches on shadow work and her own personal healing journey. Soul Slumber Party Soul Slumber Party InstagramSoul Slumber Party TikTok Soul Slumber Party FacebookShow Inquiries soulslumberpartypod@gmail.com

Dior Kunz Jr., a two-year-old boy, went missing on July 10, 2015, during a camping trip at Timber Creek Campground in Idaho with his parents, Jessica Mitchell and Dior Kunz Sr., his great-grandfather Robert Walton, and a family friend, Isaac Reinwand. The parents reported leaving Dior with Walton briefly, but upon their return, he was gone, prompting an extensive search involving law enforcement, search dogs, helicopters, and volunteers. Despite thorough searches of the area, no evidence of Dior's whereabouts was found. Various theories, including accidental disappearance, animal attack, abduction, and foul play by those present, have been proposed, but no conclusive evidence has emerged. As of 2024, the case remains unsolved, with no new leads, leaving the mystery of Dior Kunz Jr.'s disappearance unresolved.(commercial at 8:12)to contact me:bobbycapucci@protonmail.com

Dior Kunz Jr., a two-year-old boy, went missing on July 10, 2015, during a camping trip at Timber Creek Campground in Idaho with his parents, Jessica Mitchell and Dior Kunz Sr., his great-grandfather Robert Walton, and a family friend, Isaac Reinwand. The parents reported leaving Dior with Walton briefly, but upon their return, he was gone, prompting an extensive search involving law enforcement, search dogs, helicopters, and volunteers. Despite thorough searches of the area, no evidence of Dior's whereabouts was found. Various theories, including accidental disappearance, animal attack, abduction, and foul play by those present, have been proposed, but no conclusive evidence has emerged. As of 2024, the case remains unsolved, with no new leads, leaving the mystery of Dior Kunz Jr.'s disappearance unresolved.(commercial at 8:12)to contact me:bobbycapucci@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

On this episode of the episode of the podcast I get to sit down and chat with Autumn Kunz, owner of Rabbit Hole Wellness. She shares their story and what you can expect to find if you visit Rabbit Hole Wellness located at 9329 S 1300 E Unit #12. Sandy, UT 84094

In July of 2015, a family headed out for a camping trip in the woods of Idaho only for their two-year-old to vanish on the first day. The parents called 911 and were adamant that he was abducted after wandering off by himself. But after police assessed the scene and interviewed everyone present, they composed a different disturbing theory. This is the disappearance of DeOrr Kunz Jr. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In July of 2015, a family headed out for a camping trip in the woods of Idaho only for their two-year-old to vanish on the first day. The parents called 911 and were adamant that he was abducted after wandering off by himself. But after police assessed the scene and interviewed everyone present, they composed a different disturbing theory. This is the disappearance of DeOrr Kunz Jr. Learn more about your ad choices. Visit podcastchoices.com/adchoices