Signal From The Noise: By Podcast Notes

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    • Jan 26, 2023 LATEST EPISODE
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    How To Optimize Fertility In Both Males & Females (Part 1) | Huberman Lab

    Play Episode Listen Later Jan 26, 2023


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I discuss the mechanisms by which human eggs and sperm are generated, the ovulatory/menstrual cycle, the conception process and overall fertility in males and females. I also explain how, regardless of whether you seek to conceive children, optimizing egg and sperm health is directly related to vitality and longevity. I cover the nutrition-based, behavioral, supplement-based and prescription approaches to optimizing egg and sperm health, the ovulatory/menstrual cycle and fertility. In addition, I explain lifestyle choices that greatly assist or harm fertility—several of which are very surprising. I provide science-based protocols for those trying to conceive children. The tools and principles I discuss can also improve overall vitality and longevity in all people, regardless of age.  For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Maui Nui: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Fertility, Vitality & Longevity (00:04:24) Maui Nui Venison, Eight Sleep, Momentous (00:08:20) Eggs & Sperm, Genes, Fertilization (00:18:28) Puberty: Gonadotropin Releasing Hormone (GnRH), Melatonin & Leptin (00:23:38) Onset Trends of Puberty, Odors Effects (00:31:24) Female Puberty, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH) (00:35:25) AG1 (Athletic Greens) (00:36:34) Ovulatory & Menstrual Cycle (00:40:36) Follicular Phase: Egg Maturation & Ovulation, FSH & Estrogen (00:51:09) Luteal Phase: Progesterone & Estrogen, Menstruation (00:58:14) Ovulation & Libido; Luteal Phase & Malaise; Individual Variability (01:03:14) InsideTracker (01:04:18) Sex Chromosomes, Sperm (01:11:40) Tool: Testicular Temperature & Fertility (01:17:22) Sperm Production, Seminal Fluid, Vasectomy (01:24:07) Sperm Cells, Mitochondria & Motility, Intercourse Frequency & Fertilization (01:28:31) Sperm Production, GnRH, FSH, LH & Testosterone (01:36:21) Ejaculate Quality, Sperm Counts, Fertilization, Ectopic Pregnancy (01:44:14) Tool: Sexual Intercourse Frequency & Fertilization (01:53:24) Tools: Tracking Ovulation, Libido, Lubricants (01:56:42) Fecundability: Egg Quality & Woman's Age, Cumulative Pregnancy Rate (02:08:17) Miscarriages, Chromosomal Abnormalities (02:11:23) Female Fertility: Age, Follicle Testing & Anti-Mullerian Hormone (AMH) Testing (02:18:51) Male Fertility: Sperm Analysis, Age (02:24:52) Fertility & Hormone Analysis, Age (02:29:07) Fertility Effects of Sleep, Cortisol/Stress, Cannabis/Nicotine & Alcohol (02:42:40) Fertility, Sexually Transmitted Infections (STIs), Viral Infection & Cystic Fibrosis (02:47:42) Tool: Testicular Temperature & Fertility (02:51:26) Tool: Phones & Sperm Quality (02:58:06) Deliberate Cold Exposure & Fertility, Testicular Temperature, Cortisol/Stress (03:05:43) Fertility, Exercise & Mitochondrial Health; Intermittent Fasting (03:14:46) Testosterone Replacement Therapy & Sperm Production; Supplements (03:20:36) Sex Determination in Offspring, In Vitro Fertilization (IVF), Sperm Fractions (03:32:23) Postcoital Female Position & Fertilization, Sperm Quality (03:36:57) Cannabis & Sperm Motility, Libido, Pregnancy (03:42:33) Acupuncture, Fertility & Pregnancy (03:49:25) Fertility Supplements: L-Carnitine & Allicin, Coenzyme Q10 (03:56:18) Fertility Supplements: Inositol, Omega 3 Fatty Acids (04:02:50) Supplements for Hormones: Tongkat Ali, Shilajit, Zinc (04:13:02) Fertility & Prescription Medications (04:16:44) Human Reproduction & Fertility (04:20:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac

    Sam McRoberts — The Grand Redesign (EP.143)

    Play Episode Listen Later Jan 24, 2023


    Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Author, CEO of VUDU Marketing and digital nomad Sam McRoberts returns for his second appearance on Infinite Loops. This week, Sam and Jim discuss Sam's latest book ‘The Grand Redesign'. Part science-fiction, part operating manual for upgrading human OS, ‘The Grand Redesign' touches on a number of recurring Infinite Loops themes, and is available for free online (see ‘Important Links' section below). Important Links: The Grand Redesign Sam's Twitter Sam's Substack The Thinker and The Prover Tinkered Thinking's winning entry to our ‘White Mirror' competition Show Notes: Why Sam wrote the book Is the Watcher a reliable narrator? Interfering with complex systems An overview of Social OS Why we need White Mirror The kindness pledge Incentives and the Cobra Effect How do we break the Shannon limit? Jim's movie idea Improving the political and legal system The opportunities of AI Optimising our system for flourishing Finding the hidden geniuses Sam's solutions; reaching the tipping point Sam's hopes for the book MUCH more! Books Mentioned: The Grand Redesign; by Sam McRoberts The Status Game: On Human Life and How to Play It; by Will Storr Prometheus Rising; by Robert Anton Wilson House of Cards: Psychology and Psychotherapy Built on Myth; by Robyn Dawes The Lessons of History: by Will Durant and Ariel Durant Happy: Why More or Less Everything is Absolutely Fine; by Derren Brown The Inevitable: Understanding the 12 Technological Forces That Will Shape Our Future; by Kevin Kelly

    Rick Rubin: How to Access Your Creativity | Huberman Lab Podcast 107

    Play Episode Listen Later Jan 19, 2023


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- My guest is Rick Rubin, one of the most renowned music producers of all time, known for his work with a wide range of artists, including Run DMC, Public Enemy, Beastie Boys, Red Hot Chili Peppers, JayZ, Adele, Johnny Cash, LL Cool J, Slayer, Neil Young, Kanye West, Tom Petty, and many more. He is also the author of a new book, "The Creative Act: A Way of Being," which explores the creative process and how to access creativity. We discuss topics such as finding inspiration, the role of feelings as guideposts, learning from observing nature, balancing self-doubt and anxiety, and adopting new perspectives to channel the creative process. Rick also shares his thoughts on using deadlines, eliminating distractions, and how our experiences and emotions influence the creative process. Additionally, we discuss his love for professional wrestling. Our conversation can be applied to any activity or profession to access creativity. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Maui Nui: https://mauinuivenison.com/huberman Thesis: https://takethesis.com/huberman WHOOP: https://join.whoop.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Rick Rubin (00:04:08) Maui Nui Venison, Thesis, WHOOP, Momentous (00:08:23) Creativity & Ideas, Cloud Analogy  (00:12:26) Language & Creativity; Kids (00:17:36) Feelings & Creative Ideas (00:22:01) Rules, Choice & Art; Personal Taste & Other's Opinions  (00:30:20) Changing Perspective & Creativity (00:33:55) AG1 (Athletic Greens) (00:35:04) Scientific Knowledge; Opinions & Art (00:41:27) Finishing Projects; The Source & Nature (00:47:40) Perception Filters, Contrast & Novelty (00:58:42) Music & Identity, Evolving Tastes (01:03:03) InsideTracker (01:04:14) Focus, Disengaging & Subconscious; Anxiety  (01:13:22) Collaboration, Art & Rigorous Work (01:18:26) Process & “Cloud”; Perception & Storytelling (01:29:13) Limited Resolution, Considering the Inverse (01:35:38) Wrestling, Energy & Reality; Dopamine  (01:49:43) Wrestling, Style & Performance (01:52:40) Resetting Energy & Nature; Nostalgia (02:01:56) Sleep, Waking Up & Sunlight, Capturing Ideas (02:08:16) Creative Work Phases; Structure & Deadlines (02:15:32) Self-Doubt & Performance (02:19:13) Predictability & Surprise, Authenticity   (02:25:02) Past Experiences, Other's Opinions  (02:29:42) Public Opinion & Science: Light, Acupuncture & Nutrition  (02:39:44) “Look for Clues”, Belief Effects  (02:46:25) Attention, Emotion & Art (02:48:07) Mantra Meditation, Awareness Meditation  (02:57:33) Rick Rubin Questions, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac

    E110: 2023 Bestie Predictions!

    Play Episode Listen Later Jan 19, 2023


    All-In with Chamath, Jason, Sacks & Friedberg: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- (0:00) Bestie New Year catch-up! (2:44) Prediction 1: 2023's biggest political winner (17:25) Prediction 2: 2023's biggest political loser (21:57) Prediction 3: 2023's biggest business winner (30:34) Prediction 4: 2023's biggest business loser (42:03) Prediction 5: 2023's biggest business deal (52:41) Prediction 6: 2023's most contrarian belief (1:03:03) Prediction 7: 2023's best-performing asset (1:07:50) Prediction 8: 2023's worst-performing asset (1:14:46) Prediction 9: 2023's most anticipated trend (1:21:40) Prediction 10: 2023's most anticipated media (1:27:07) Breaking news: OpenAI reportedly in talks to sell existing shares at a ~$29B valuation Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://www.wsj.com/articles/citadel-posts-record-revenues-for-hedge-fund-securities-operations-11672942665 https://www.reuters.com/world/saudi-arabia-gathers-chinas-xi-with-arab-leaders-new-era-ties-2022-12-09/ https://www.nytimes.com/2023/01/03/business/europe-natural-gas-prices.html https://www.nytimes.com/2023/01/04/technology/salesforce-layoffs.html https://www.wsj.com/articles/amazon-to-lay-off-over-17-000-workers-more-than-first-planned-11672874304 https://twitter.com/DavidSacks/status/1598076726671642624 https://www.nytimes.com/2022/12/30/world/asia/xi-putin-china-russia.html https://twitter.com/JenniferJJacobs/status/1611052287954149377 https://www.bloomberg.com/news/articles/2023-01-03/blackstone-s-breit-gets-4-billion-from-university-of-california https://www.nbcnews.com/politics/congress/gop-rebels-block-kevin-mccarthy-defiance-trump-rcna64280 https://www.wsj.com/articles/chatgpt-creator-openai-is-in-talks-for-tender-offer-that-would-value-it-at-29-billion-11672949279

    AMA #3: Adaptogens, Fasting & Fertility, Bluetooth/EMF Risks, Cognitive Load Limits & More

    Play Episode Listen Later Jan 18, 2023


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Welcome to a sneak peek of the third Ask Me Anything (AMA) episode, part of Huberman Lab Premium. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium Timestamps (00:00:00) Introduction 00:00:00 Introduction 00:01:27 Adaptogens [Justine Bevilacqua] 00:29:42 Huberman Lab Premium In the full 1.5 hour+ AMA episode, we discuss: Caloric restriction in fertile women Cognitive load limits Potential risks of Bluetooth, Wi-Fi, EMFs Creatine and aging Title Card Photo Credit: Mike Blabac Disclaimer

    #351 – MrBeast: Future of YouTube, Twitter, TikTok, and Instagram

    Play Episode Listen Later Jan 18, 2023


    Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- MrBeast is a legendary YouTube creator. Please support this podcast by checking out our sponsors: – House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order – Eight Sleep: https://www.eightsleep.com/lex to get special savings – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: MrBeast Main Channel: https://youtube.com/@MrBeast MrBeast Reacts: https://youtube.com/@BeastReacts MrBeast Gaming: https://youtube.com/@MrBeastGaming MrBeast Philanthropy: https://youtube.com/@BeastPhilanthropy MrBeast's TikTok: https://tiktok.com/@mrbeast MrBeast's Twitter: https://twitter.com/MrBeast MrBeast's Instagram: https://instagram.com/mrbeast Feastable's Website: https://feastables.com MrBeast Burger's Website: https://mrbeastburger.com MrBeast's Merch: https://shopmrbeast.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT

    MFM Mini-Camp, Lessons from Selling a Company, and Storytelling Wins

    Play Episode Listen Later Jan 18, 2023


    My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Episode 405: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about what happens when Shaan leaves the house and meets up with other founders, the power of storytelling, the things you learn when you sell a company and how to hire a researcher. Want to see more MFM? Subscribe to the MFM YouTube channel here. ----- Links: * Alpha Paw * Genius Litter * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ------ Show Notes: (04:20) - Shaan leaves the house and meets cool people (13:15) - When Ramon pretended to be an electrician (18:30) - Power of storytelling (21:25) - Age and perception (28:25) - Frame break (30:10) - Things you learn when you sell a company (46:05) - How to hire a researcher ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

    Creators, Creativity, and Technology with Bob Iger

    Play Episode Listen Later Jan 18, 2023


    A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- with @robertiger @cdixon @smc90A wide-ranging conversation with Bob Iger on the interplay between technology, content, and distribution; as well as Bob's journey -- and that of various creators! -- especially as the industry evolved from TV and cable to the advent of the internet/ web 1.0 to 2.0 to briefly touching on web3 and other emerging technologies. As well as topics top of mind for all company and community builders: from build vs. buy and the innovator's dilemma, to managing creativity, decentralization, remote work, and much more. Subscribe to web3 with a16z: https://podcasts.apple.com/us/podcast/web3-with-a16z-crypto/id1622312549 Stay Updated: Find us on Twitter: https://twitter.com/a16zFind us on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

    #298 The Root Cause Of Disease That Nobody's Talking About With Dr Zach Bush

    Play Episode Listen Later Jan 18, 2023


    Feel Better, Live More with Dr Rangan Chatterjee ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- I believe that conversation matters; that long form nuanced conversation is what we need now more than ever, to make the world a better place. And for me, part of that means exposing ourselves to new ideas, new concepts and new ways of thinking that we may previously have not been exposed to. This week's guest on my Feel Better Live More Podcast is someone who fits that bill perfectly.Dr Zach Bush is a medical doctor and founder of the non-profit Farmer's Footprint, created to find root cause solutions for human and ecological health. His passion for education reaches across many disciplines, including genomics, the immune system, and gut brain health.Zach spent many years as a conventional doctor, specialising in internal medicine, endocrinology and hospice care. Disillusioned with the state of Western medicine, he began taking an integrative approach, studying the body's microbiomes in relation to health, disease and food systems. Today though, Zach describes his life and work as ‘dedicated to the health of humanity and the planet we call home'.In this conversation, Zach makes the case for a revolution in how we understand ourselves, our fellow humans, our healthcare and farming systems – and how we save the world. This episode is a rollercoaster ride through biology, physics, philosophy, economics and environmentalism – all sprinkled with a good dose of inspiration.Zach and I share the view that healthcare needs radical change. It can no longer be about doctors telling patients what's wrong and prescribing drugs and treatments that don't look at the whole person.We discuss how traits of ego, individualism and competition aren't really human at all. And Zach explains how the realisation that all living beings are energetically connected and interdependent is the key to transformation – we cannot thrive as one species if we wipe out others.We also talk about saving our soil and our food systems through regenerative agriculture, and encouraging individuals, farmers and big industry to work together to save the internal and external ecosystems that none of us could live without.Yes, these are big topics. But ultimately, Zach's message is one of hope. He's not afraid to put forward big solutions, and they're all made up of steps each one of us can start taking from today.This is a really special conversation. It's honest, evocative and at times, provocative. I hope you enjoy listening.Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.Thanks to our sponsors:https://www.athleticgreens.com/livemorehttps://www.vivobarefoot.com/livemorehttps://www.leafyard.com/livemoreShow notes https://drchatterjee.com/298DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Hosted on Acast. See acast.com/privacy for more information.

    Bad Moms with Emily Oster

    Play Episode Listen Later Jan 14, 2023


    Honestly with Bari Weiss ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- When my wife Nellie was pregnant last year, we became obsessed with Economist Emily Oster's book, Expecting Better: Why the Conventional Pregnancy Wisdom Is Wrong–and What You Really Need to Know. Amidst a barrage of conflicting and confusing pregnancy advice, Oster laid out the data on everything we needed to know. Despite what doctors said, sushi, cheese, and the occasional glass of wine were all okay during those nine long months. It gave us the much needed calm we needed during a time of so much uncertainty.  With her two subsequent books Cribsheet and The Family Firm, Oster popularized a new phenomenon that has defined our generation of parents: data-driven parenting. It ditches the long lists of paternalistic rules, and instead examines peer-reviewed evidence and lets parents make their own informed decisions about their kids based on risks and tradeoffs. Nowhere was the Oster mentality more front and center, and more divisive, than during Covid. She argued very early on in the pandemic for less draconian and more nuanced policies. She wrote pieces in the Atlantic like, Schools Aren't Superspreaders and Your Unvaccinated Kids Is Like A Vaccinated Grandma, when those words were considered heresy. And while she made quite a few enemies on the left over the last few years, recently she wrote Let's Declare A Pandemic Amnesty, and earned herself some enemies on the right as well. Today, my wife Nellie Bowles joins me to talk to Oster about why a Harvard-educated economist at Brown University decided to become a parenting guru, how she used her parenting framework to become a leading expert on pandemic policies, and the unwinnable position of… actually following the science. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Developing A Rational Approach To Supplementation For Health & Performance| Huberman Lab

    Play Episode Listen Later Jan 13, 2023


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can't be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Supplements (00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol (00:11:51) Momentous, LMNT, Helix Sleep (00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins (00:21:07) Supplement Considerations: Cost, Nutrition & Schedule (00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens (00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition (00:33:06) Supplements for Gut Microbiome, Brain Fog (00:35:59) InsideTracker (00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements (00:38:35) Core Supplement Questions & Meeting Foundational Needs (00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine (00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin (00:55:55) Melatonin Caution (00:58:11) Supplement Dependency?, Placebo Effects (01:02:45) AG1 (Athletic Greens) (01:03:53) Nutrition & Behavior for Hormone Health (01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root  (01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions  (01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork  (01:23:06) Testosterone Supplement: Tongkat Ali, Libido  (01:27:24) Menstrual Cycle, Birth Control & Fertility (01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine  (01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine (01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements (01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids (01:47:25) Food-Mimic Supplements, Protein  (01:50:09) Kids, Aging & Supplements (01:55:25) A Rational Supplementation Protocol (01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac

    John Mack on Life Lessons From Financial Crisis

    Play Episode Listen Later Jan 13, 2023


    Masters in Business: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Bloomberg Radio host Barry Ritholtz speaks with the legendary John Mack, former chief executive officer and chairman of the board at Morgan Stanley. His memoir of his life and 34-year tenure at Morgan Stanley — “Up Close and All In: Life Lessons From a Wall Street Warrior” — was published in October. See omnystudio.com/listener for privacy information.

    Ryan Holiday Reveals How Much Best Selling Authors Make, Crazy Peter Thiel Stories & More

    Play Episode Listen Later Jan 13, 2023


    My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Episode 370: Sam Parr (@TheSamParr) talks to best-selling author, podcaster, bookstore owner, and former marketing director for American Apparel, Ryan Holiday (@RyanHoliday), about how to make money in publishing, creating a masterpiece, and investing in a ghost town. ----- Links: * Ryan Holiday * Trust Me I'm Lying: Confessions of a Media Manipulator * Brass Check * The Painted Porch Bookshop * Vinyl Me, Please * Ghost Town Living * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ------ Show Notes: (03:55) - Does the bestseller list still matter? (05:30) - Breaking down the #s of the publishing industry (29:20) - How big is your team? (35:10) - Who do you admire? (44:40) - The pros and cons of reality distortion fields (50:40) - Ryan's ghost town ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

    Connecting With Pele

    Play Episode Listen Later Jan 6, 2023


    Big Questions with Cal Fussman: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- On the day of Pele's burial, Cal goes to the archives for an interview he did with the man many consider to be the greatest soccer player of all time. This podcast gets to the essence of the Brazilian superstar who connected with almost everyone on the planet. Not only did Pele make everyone smile, he once halted a war. After three years of disconnection due to the pandemic, we need to connect now more than ever. Pele shows us how.

    #236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.

    Play Episode Listen Later Jan 6, 2023


    Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Kellyann Niotis is a neurologist specializing in risk reduction strategies for the prevention or slowing of neurodegenerative disorders. In this episode, Kellyann provides an overview of the various diseases associated with neurodegeneration, including, but not limited to, Alzheimer's disease, Lewy body dementia, and Parkinson's disease. She goes in-depth on Parkinson's disease, explaining its pathology, role in movement capacity, very early warning signs, and the role of anxiety and sleep. Similarly, she provides an in-depth discussion of Alzheimer's disease, including the latest in screening, genetics, and tools/strategies for prevention. She ties the discussion together by explaining the differences and commonalities among the various diseases of neurodegeneration and the potential causative triggers, and she highlights the importance of early screening, cognitive testing, and taking the proper steps to lowering the risk of disease. We discuss: Kellyann's background, training, and interest in the brain [2:30]; A primer on neurodegeneration: different types, prevalences, interventions, and more [5:30]; Overview of Parkinson's disease and neuromuscular disorders including ALS [16:00]; Parkinson's disease: early signs, diagnosis, genetics, causative triggers, and more [17:30]; Interventions to delay or avoid Parkinson's disease, and the role of sleep and anxiety [31:15]; The challenge of standardizing early interventions for Parkinson's disease without a clear biomarker [39:45]; Alzheimer's disease: pathophysiology and the role of the amyloid and tau proteins [47:45]; Can PET scans be informative for diagnosing Alzheimer's disease? [51:15]; Tau accumulation in the brain, tau scans, serum biomarkers, and possible early detection of Alzheimer's disease pathology [57:00]; Cognitive testing explained [1:03:30]; The challenge of identifying the stage of the disease and why drugs have not shown efficacy [1:14:45]; The association between hearing loss and dementia [1:17:45]; The relationship between oral health and neurodegenerative diseases [1:21:30]; Genetic risk for Alzheimer's disease [1:24:45]; What one's mitochondrial haplotype can reveal about their risk of neurodegenerative disease [1:32:30]; The positive impact of exercise on brain health [1:37:00]; High blood pressure as a risk factor [1:40:00]; Why women are disproportionately affected by Alzheimer's disease [1:44:15]; Final takeaways: the future of understanding neurodegenerative disease and further reducing risk [1:46:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    BEST OF 2022: PART 2 – Malcolm Gladwell, Casey Neistat, Peter Attia, Gabor Maté, Sylvia Earle and Many More! | The Rich Roll Podcast

    Play Episode Listen Later Jan 6, 2023


    Rich Roll Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- As 2022 comes to a close and a new year beckons, we are presented with an opportunity to reflect on the past twelve months. Explore new aspirations. And set intentions for the year to come. Allow me to indulge this truth by introducing Part Two of my annual yearbook—an auditory anthology of the year's most compelling conversations. Enjoy the best of the year.Guest List + Full Episode Links:RRP 692: Malcolm GladwellRRP 723: Mel RobbinsRRP 715: Casey NeistatRRP 718: Whitney CummingsRRP 695: Peter Attia, MDRRP 678: Gemma Newman, MDRRP 702: Dr. Gabor MatéRRP 714: Robynne Chutkan, MDRRP 703: Max FisherRRP 660: Sylvia EarleRRP 701: Ken RideoutRRP 694: Colin O'Brady & Jenna BesawRRP 705: Paul Conti, MDRRP 670: Earthling Ed WintersRRP 681: Chip ConleyShow notes + MOREWatch on YouTubeNewsletter Sign-UpToday's Sponsors:Levels: levels.link/RICHROLLNavitas Organics: navitasorganics.com/richrollWhoop: WHOOP.com BetterHelp: BetterHelp.com/richroll.Athletic Greens: athleticgreens.com/richroll Peace + Plants,Rich Hosted on Acast. See acast.com/privacy for more information.

    O'Shaughnessy Ventures is Here (EP.140)

    Play Episode Listen Later Jan 4, 2023


    Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- We've landed. After 3 months of stealth mode, sneak-peeks, and surprise announcements, we have finally hit launch day. In this special episode of Infinite Loops, hosted by Patrick O'Shaughnessy, Jim chats through the rationale behind founding OSV, the positive impact he wants it to have on the world, and the ways you can get involved. Important Links: OSV's Website Jim's Twitter Show Notes: The origins of OSV Why OSV does not invest third parties' money The story of Jim's investment in Stability AI What has surprised Jim the most about the world of AI What OSV will look like on 1 January 2023: the four verticals Assembling the OSV team OSV's objective function Where the majority of Jim's energy will be directed How you can get involved with OSV

    RR 231: Investing Basics and Common Questions  (plus Reading Habits w/ Amer Kaissi) (EP.231)

    Play Episode Listen Later Dec 29, 2022


    The Rational Reminder Podcast ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Today is our final episode featuring just the two of us before our annual wrap-up show, and we thought we would use this opportunity to cover some important foundational aspects of rational investing. Ben goes over some of the most fundamental concepts about market prices, risk, and actual returns before answering five common questions that relate to this level of information. From investing in an employer's stock to predicting the future and real estate comparisons, these five touch-points are always worth returning to, and should even interest the more experienced of our listeners. For the second half of the show, we offer a quick book review of The Culture Playbook by Daniel Coyle, and have a brief and illuminating conversation with Professor Amer Kaissi about his book, Humbitious, and some of his thoughts on the part that reading plays in rich and progressive life. Press play to catch all this and more on the Rational Reminder Podcast.   Key Points From This Episode:   Picking up a thread from our discussion on the 2% Rule. (0:06:05) Getting to grips with investing basics. (0:10:45) How market prices work in response to traders' actions and risk. (0:17:59) The main determinants of actual returns and starting points for your portfolio. (0:23:15) Unknowable futures and the eternal doom and gloom predictions. (0:35:43) Assessing the value of owning an employer's stock. (0:38:21) Holding stock picks in Tax-Free Savings Accounts. (0:42:07) How to prepare a portfolio when a recession is predicted. (0:43:49) Comparing investments in real estate with the stock market. (0:45:14) Weighing the value of building and emergency fund. (0:47:11) A thirty-second recap of our episode with Cliff Asness. (0:50:06) Today's book review focussing on the lesson from The Culture Playbook by Daniel Coyle. (0:51:48) Professor Kaissi shares a quick summary of his book, Humbitious. (0:58:40) The potential to develop characteristics and the role that reading plays. (0:59:38) Professor Kaissi talks about his reading habits. (1:02:12) Application of ideas from books and how Professor Kaissi captures and organizes information in his own reading. (1:05:15) A few of Professor Kaissi's favourite book recommendations and how to increase your reading habit. (1:08:52)     Participate in our Community Discussion about this Episode: https://community.rationalreminder.ca/t/episode-231-investing-basics-and-common-questions-plus-reading-habits-w-amer-kaissi-discussion-thread/20716 Books From Today's Episode: Humbitious: The Power of Low-Ego, High-Drive Leadership — https://amzn.to/3WjHjry Mindset — https://amzn.to/3Wzl7Kr Quiet — https://amzn.to/3htlN4X The Five Dysfunctions of a Team — https://amzn.to/3YmKqRv The SPEED of Trust — https://amzn.to/3UWCljq Top Five Regrets of the Dying — https://amzn.to/3uQcUWf The Assertiveness Workbook — https://amzn.to/3VVDVUf How to Raise Your Self Esteem — https://amzn.to/3BDM33p Ego Is the Enemy — https://amzn.to/3BAyCkZ Links From Today's Episode: Rational Reminder on iTunes — https://itunes.apple.com/ca/podcast/the-rational-reminder-podcast/id1426530582. Rational Reminder Website — https://rationalreminder.ca/  Shop Merch — https://shop.rationalreminder.ca/ Join the Community — https://community.rationalreminder.ca/ Follow us on Twitter — https://twitter.com/RationalRemind Follow us on Instagram — @rationalreminder Benjamin on Twitter — https://twitter.com/benjaminwfelix Cameron on Twitter — https://twitter.com/CameronPassmore Amer Kaissi on Twitter — https://twitter.com/amerkaissi10 Amer Kaissi on LinkedIn — https://www.linkedin.com/in/amer-kaissi-ph-d-38258919/ Amer Kaissi — http://www.amerkaissi.com 'The Value of Goals-Based Financial Planning' — https://www.financialplanningassociation.org/article/journal/JUN15-value-goals-based-financial-planning 'Excessive Extrapolation and the Allocation of 401(k) Accounts to Company Stock' — http://independent401kadvisors.com/library_articles/ExcessiveExtrapolation.pdf 'The Agony of Ecstasy: The risks and rewards of a concentrated stock position' — https://assets.jpmprivatebank.com/content/dam/jpm-wm-aem/global/pb/en/insights/eye-on-the-market/agony-ecstasy-2021.pdf 'The financial resilience and financial well-being of Canadians during the COVID-19 pandemic' — https://www150.statcan.gc.ca/n1/pub/75f0002m/75f0002m2021008-eng.htm

    Blake Scholl: How Boom Supersonic Took Flight

    Play Episode Listen Later Dec 29, 2022


    Starting Greatness with Mike Maples: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- More than fifty years after the first Concorde took flight, consumer air travel is actually SLOWER. Blake Scholl and his team at Boom Supersonic are out to reverse this stagnation and change how we think about commercial aviation. In this episode, Mike Maples, Jr of FLOODGATE interviews Scholl to learn more about the history of American aviation, the origins of Boom Supersonic and the challenges it faces now, and how tech founders are exploring unfamiliar spaces with great success.

    #234 ‒ Chris Hemsworth on Limitless, longevity, and happiness

    Play Episode Listen Later Dec 29, 2022


    Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Chris Hemsworth, best known for his role as Thor in the Marvel movies, joins Peter to discuss his recent work in the docuseries called Limitless. In the docuseries, Chris undertook extreme challenges to explore his physical and emotional limits and gain insights into longevity. In this episode, Chris discusses these many challenges—from fasting to arctic swims to 100-foot rope climbs—as well as the insights that he gained from each. Peter, who also played a role in the docuseries, guides Chris through the science of longevity, including what Chris's APOE-ε4 genotype means for his risk of Alzheimer's disease. Additionally, Chris describes how his outlook on health, happiness, work-life balance, and more have changed from his experience on Limitless. We discuss: Limitless: how Chris got involved and his overall experience filming the docuseries [3:00]; “Fasting” ‒ ep. 3 of Limitless in which Chris attempts a 4-day fast [8:15]; “Shock” ‒ ep. 2 of Limitless in which Chris swims in the Arctic Ocean [12:15]; Cold exposure: the potential physical and mental benefits [19:30]; “Strength” ‒ ep. 4 of Limitless in which Chris explores how muscle can improve longevity [21:15]; The APOE-ε4 genotype and Alzheimer's disease risk [31:30]; How Chris uses sauna [39:45]; “Acceptance” - ep. 6 of Limitless in which Chris explores the meaning of life by contemplating death [42:15]; Chris's new perspective on work-life balance [52:00]; “Stress-Proof” - ep. 1 of Limitless in which Chris learns about the impact of stress and how to manage it [54:30]; Chris reflects on his intrinsic motivation driven by both fear and purpose [58:00]; Chris reflects on his career arc and how his presence as an actor has evolved [1:01:15]; How Chris's outlook has changed since filming Limitless [1:05:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    Austin Rief: Building & Selling The Morning Brew for Millions In 5 Years, Side Hustle Ideas, & More | My First Million With Sam Parr and Shaan Puri #398

    Play Episode Listen Later Dec 24, 2022


    My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Episode 398: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk to Morning Brew CEO Austin Rief (@austin_rief) about building, growing and selling a newsletter valued at $75M in 5 years, discussing the question are newsletters still worth doing, and a few good side hustle ideas to start now. ----- Links: * Morning Brew * Toptal * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ------ Show Notes: (01:00) - Morning Brew origin story (19:10) - ad sales (24:10) - Austin's strengths (32:15) - Austin's upbringing (42:55) - what did you do with your new found wealth? (45:55) - ideas brainstorm (01:13:14) - future plans ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

    #235 ‒ Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D.

    Play Episode Listen Later Dec 24, 2022


    Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder and powerlifter, and two-time previous podcast guest. In this episode, Layne discusses his training as a powerlifter and shares training principles that non-powerlifters can apply to improve muscle strength and mass. Layne goes in-depth on creatine supplementation, including the benefits for lean mass and strength, and addresses the common arguments against its regular usage. Additionally, Layne touches on many areas of nutrition, including how his opinions have changed on certain topics. Layne also touches on the subjects of protein, fiber, and fat in the diet, as well as the different tools and dietary approaches for energy restriction. We discuss: The sport of powerlifting and Layne's approach during competitions [2:30]; Training for strength: advice for beginners and non-powerlifters [13:15]; Low-rep training, compound movements, and more tips for the average person [23:15]; How strength training supports longevity and quality of life: bone density, balance, and more [28:15]; Peak capacity for strength as a person ages and variations in men and women [33:00]; Effects of testosterone (endogenous and exogenous) on muscle gain in the short- and long-term [36:45]; How Layne is prepping for his upcoming IPF World Masters Powerlifting competition [44:00]; Creatine supplementation [54:30]; How important is rep speed and time under tension? [1:05:30]; Validity of super slow rep protocols, and the overall importance of doing any exercise [1:12:45]; Navigating social media: advice for judging the quality of information from “experts” online [1:23:00]; Layne's views on low-carb diets, the tribal nature of nutrition, and the importance of being able to change opinions [1:34:45]; Where Layne has changed his views: LDL cholesterol, branched-chain amino acid supplementation, intermittent fasting, and more [1:42:00]; The carnivore diet, elimination diets, and fruits and vegetables [1:55:15]; Fiber: Layne's approach to fiber intake, sources of fiber, benefits, and more [2:00:15]; Confusion around omega-6 polyunsaturated fatty acids and the Minnesota Coronary Experiment [2:05:00]; Layne's views on fats in the diet [2:13:00]; Flexible dieting, calorie tracking, and the benefits of tracking what you eat to understand your baseline [2:18:00]; The nutritional demands of preparing for a bodybuilding show [2:30:45]; The psychological effects of aging and changes to one's identity [2:42:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    The Science of Creativity & How to Enhance Creative Innovation | Episode 103

    Play Episode Listen Later Dec 24, 2022


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I explain how the brain engages in creative thinking and, based on that mechanistic understanding, the tools to improve one's ability to think creatively and innovate in any area. I discuss how convergent and divergent thinking are essential for generating creative ideas and provide three types of meditation tools (open monitoring meditation, focused attention meditation & non-sleep deep rest; NSDR), which improve our ability to engage in these creative thinking patterns in specific and powerful ways. I also discuss how dopamine and mood contribute to the creative process and describe behavioral, nutritional and supplementation-based approaches for increasing dopamine to engage in creative thought and implementation. I explain how movement and storytelling (narrative) approaches can generate novel creative ideas and how substances like alcohol, cannabis, and psilocybin impact our creative ability. Excitingly, creativity is a skill that can be cultivated and enhanced; this episode outlines many tools to help anyone access creativity and apply creative patterns of thought to different domains of life. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com/huberman Thesis: https://takethesis.com/huberman LMNT: https://drinklmnt.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Creativity (00:04:30) ROKA, Thesis, LMNT, Momentous (00:08:51) What is Creativity? (00:11:16) Creativity in Visual Arts, Escher & Banksy (00:23:37) Neural Circuits of Creativity (00:31:58) AG1 (Athletic Greens) (00:33:13) Creative Ideas & Divergent Thinking (00:42:09) Testing Creative Ideas & Convergent Thinking (00:46:41) Dopamine, Convergent & Divergent Thinking Pathways (00:57:02) InsideTracker (00:58:06) Tool: Open Monitoring Meditation & Divergent Thinking (01:07:38) Tool: Focused Attention Meditation & Convergent Thinking (01:11:06) Mood, Creativity & Dopamine (01:16:00) Tool: Mood Calibrating, Caffeine & Dopamine (01:23:41) Dopamine Supplementation; L-Tyrosine, Caffeine (01:30:15) Tool: Non-Sleep Deep Rest, Mesocortical Dopamine & Divergent Thinking (01:43:130 Serotonin, Psylocibin & Creative Thinking (01:49:13) Alcohol & Autobiographical Scripting; Cannabis (01:52:04) Attention Deficit Hyperactivity Disorder (ADHD) & Creativity (01:54:45) Tool: Movement & Divergent Thinking (02:01:02) Tool: Narratives & Storytelling for Creativity (02:14:47) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer Title Card Photo Credit: Mike Blabac

    Launching and growing a podcast | Chris Hutchins (All the Hacks, Wealthfront, Google)

    Play Episode Listen Later Dec 22, 2022


    Lenny's Podcast: Product | Growth | Career ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Chris Hutchins recently left his position as Head of New Product Strategy at Wealthfront to focus full-time on his podcast, All the Hacks. If you're thinking about starting your own podcast or are simply interested in the process, be sure to check out today's episode. We dive deep on all things podcasting: the pros and cons, how to climb the charts, and how much time you should expect to spend on each episode from start to finish. We talk in-depth about the process, from pre-production to publication, and share all of the products we use for recording, editing, and publishing. Chris also offers some important tips and tricks on how to get your first subscribers and how to market and grow your podcast, as well as some incredible money-saving hacks that you can start implementing today.—Find the full transcript here: https://www.lennyspodcast.com/launching-and-growing-a-podcast-chris-hutchins-all-the-hacks-wealthfront-google/#transcript—Thank you to our wonderful sponsors for supporting this podcast:• Notion—One workspace. Every team: https://www.notion.com/lennyspod• Vanta—Automate compliance. Simplify security: https://vanta.com/lenny• Lenny's Job Board—Hire the best product people. Find the best product gigs: https://www.lennysjobs.com/talent—Where to find Chris Hutchins:• Twitter: https://twitter.com/hutchins• LinkedIn: https://www.linkedin.com/in/chrishutchins/• Website: https://chrishutchins.com/—Where to find Lenny:• Newsletter: https://www.lennysnewsletter.com• Twitter: https://twitter.com/lennysan• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/—Referenced:• All the Hacks podcast: https://www.allthehacks.com/• All the Hacks newsletter: https://allthehacks.com/email• Andy Rachleff on Twitter: https://twitter.com/arachleff• Kerri Walsh Jennings on All the Hacks: https://www.allthehacks.com/performance-psychology-kerri-walsh-jennings/• Descript: https://www.descript.com/• Erika Taught Me podcast: https://podcasts.apple.com/us/podcast/erika-taught-me/id1650076906• Leigh Rowan on All the Hacks: https://www.allthehacks.com/travel-hacks-leigh-rowan/• Kevin Kelly's “1,000 True Fans”: https://kk.org/thetechnium/1000-true-fans/• Emily Oster's books: https://emilyoster.net/writing/• Chris Hutchins on The Kevin Rose Show: https://podcast.kevinrose.com/guests/chris-hutchins/• Nick Gray's newsletter: https://nickgray.net/signup-for-email-updates/• The 2-Hour Cocktail Party: How to Build Big Relationships with Small Gatherings: https://www.amazon.com/2-Hour-Cocktail-Party-Relationships-Gatherings-ebook/dp/B0B2KW6T7J• MrBeast on YouTube: https://www.youtube.com/channel/UCX6OQ3DkcsbYNE6H8uQQuVA• Gary Vaynerchuk on Twitter: https://twitter.com/garyvee• The Danny Miranda Podcast: https://podcasts.apple.com/us/podcast/the-danny-miranda-podcast/id1532160275• Ray Dalio on Twitter: https://twitter.com/RayDalio• Danny Miranda's newsletter on Substack: https://dannymiranda.substack.com/• ATRX2100 mic bundle on Amazon: https://www.amazon.com/Audio-Technica-ATR2100X-USB-Microphone-Bundle-Filter/dp/B082SYHRY9/r• Riverside: https://riverside.fm/• Focusrite Scarlett 2i2 on Amazon: https://www.amazon.com/Focusrite-Scarlett-Audio-Interface-Tools/dp/B07QR73T66• Sony Alpha 7C mirrorless full-frame camera on Amazon: https://www.amazon.com/Sony-Alpha-Full-Frame-Mirrorless-Camera/dp/B08HVZLQ4F• Adobe Audition: https://www.adobe.com/products/audition.html• Pro Tools: https://www.avid.com/pro-tools• Podpage: https://www.podpage.com/• Simplecast: https://www.simplecast.com/• Chartable: https://chartable.com/• Podstatus: https://podstatus.com/• Overcast: https://overcast.fm/• Happy Money: https://www.amazon.com/Happy-Money-Ken-Honda-audiobook/dp/B07MJHJ57T/• Vagabonding: An Uncommon Guide to the Art of Long-Term World Travel: https://www.amazon.com/Vagabonding-Uncommon-Guide-Long-Term-Travel/dp/0812992180• Die with Zero: https://www.amazon.com/Die-Zero-Getting-Your-Money/dp/0358099765• Animal Spirits Podcast: https://podcasts.apple.com/us/podcast/animal-spirits-podcast/id1310192007• Mythic Quest on AppleTV+: https://tv.apple.com/us/show/mythic-quest• Unclaimed money: https://www.usa.gov/unclaimed-money• Savendeals.com: https://www.savendeals.com/—In this episode, we cover:(00:00) Chris's background(03:25) Lesson's from Wealthfront(09:25) Why storytelling and communication are every bit as important as the product(11:04) Why you need to understand the user's experience and keep up with what others are building(14:56) Why you should focus on overall impact, not just doing what your boss wants(17:39) Why Chris likes working on big, crazy ideas(19:10) The early days of Chris's All the Hacks podcast(21:34) The pros and cons of starting a podcast(24:19) The time required to produce an episode(27:09) How Lenny started his podcast (28:29) Launch lessons and how Apple rankings work(30:49) Why you need to create authentic content(32:57) Be one person's favorite podcast(35:01) How Chris ideated and titled All the Hacks(40:09) How to get started and get your first subscribers(43:52) How Gary Vaynerchuk used Twitter to establish authority (45:07) How to take advantage of platforms with built-in growth engines(47:42) The power of in-person interviews(48:57) How to pitch to other podcasts(51:27) Equipment and products for producing podcasts(57:36) How many downloads it takes in order to be taken seriously(1:01:28) Using Overcast as a growth lever(1:09:02) Lightning round—Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com. Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

    18 Things You Didn't Know About Marcus Aurelius

    Play Episode Listen Later Dec 22, 2022


    The Daily Stoic: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- It is amazing that Meditations, year after year and read after read, feels both incredibly timely and incredibly timeless (there's a reason the book has endured now for almost twenty centuries). It's amazing that a person so famous—known to millions in his own lifetime and subject to countless books and articles and movies—could still be giving off new secrets, but indeed that's what he's doing.Today, we examine 18 things you didn't know that shaped the life of that person, Marcus Aurelius.

    EP 26 - Steven Sinofsky on leading Office & Windows at Microsoft and the art of writing well

    Play Episode Listen Later Dec 22, 2022


    Aarthi and Sriram's Good Time Show ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- This week's special guest is Steven Sinofsky, one of our favorite techno-optimists responsible for shipping Windows and Office products at Microsoft used by billions of people. He is also the author of one of the most popular Substack books - https://hardcoresoftware.learningbyshipping.com In this episode we talked about Steven's early days at Microsoft, his famous internet memo, working with Bill Gates, and the traits he sees in good leaders and founders, how to set company culture, his experience leading Office and Windows teams at Microsoft, and the secret behind his ability to write well.

    700: How Rob Dyrdek Fits Family, Real Estate, and $100M Businesses into His Day

    Play Episode Listen Later Dec 22, 2022


    BiggerPockets Real Estate Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Rob Dyrdek is one of the most well-known pro skaters, entrepreneurs, and media figures of all time. He essentially owned the MTV lineup for years with hit shows such as Rob & Big, Rob Dyrdek's Fantasy Factory, and Ridiculousness. At first glance, Rob may look like a phenomenal skater who turned his passion into something profitable. But behind the half pipes is an almost unbelievable amount of discipline, wisdom, and time optimization that only a select few know about.Rob, like many entrepreneurs, ditched school early on when he realized that his talents were best used elsewhere. He left high school at sixteen, went on to compete in the highest level of skateboarding, and started his first company at seventeen. He was bringing in millions of dollars a year at an age where money is almost incomprehensible. Rob was fueled by creation, starting dozens of businesses that were doing millions in revenue but weren't making a financial difference in his life. So, he took a high-level view of what was worth keeping and cut out everything but that.From then on Rob began investing down two major avenues—businesses and real estate. Most people who follow Rob know about the former, but very few know about the latter. Now, Rob's on the show to help us celebrate the 700th episode of the BiggerPockets Real Estate Podcast and show us how we too can make millions of dollars by tracking every minute of our day as intelligently as possible. In This Episode We Cover:Becoming an entrepreneur and Rob's earliest business venturesWhy quantity over quality is key when building businesses and brandsReal estate syndications and why Rob will only touch a certain type of propertyThe “soul-sucking” landlord life and why it is NOT for everyoneRob's recession-proof plan that will make him millions even as investing fear peaksTracking your life and how doing so will make you richer and happier almost automaticallyBuilding your financial framework and how so many doors open after you do soAnd So Much More!Links from the ShowFind an Investor-Friendly Real Estate AgentBiggerPockets Youtube ChannelBiggerPockets ForumsBiggerPockets Pro MembershipBiggerPockets BookstoreBiggerPockets BootcampsBiggerPockets PodcastBiggerPockets MerchListen to All Your Favorite BiggerPockets Podcasts in One PlaceLearn About Real Estate, The Housing Market, and Money Management with The BiggerPockets PodcastsGet More Deals Done with The BiggerPockets Investing ToolsFind a BiggerPockets Real Estate Meetup in Your AreaDavid's BiggerPockets ProfileDavid's InstagramDavid's YouTube ChannelRob's YouTubeRob's InstagramRob's TikTokRob's TwitterRob's BiggerPockets ProfileWhy Elite Investors Know Exactly How Much Their Time Is WorthSyndications and Everything You Need to Know BEFORE You InvestHere's What It Takes to Succeed as an EntrepreneurConnect with Rob Dyrdek:Rob's WebsiteRob's InstagramRob's TwitterRob's PodcastClick here to check the full show notes: https://www.biggerpockets.com/blog/real-estate-700Interested in learning more about today's sponsors or becoming a BiggerPockets partner yourself? Check out our sponsor page!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    20VC: Mailchimp's Ben Chestnut on The Biggest Leadership Lessons Scaling to a $12Bn Acquisition and $1BN+ ARR, The Secret to Happiness, Being a Great Husband and Father & Why 2021 was the Right Time To Sell to Intuit

    Play Episode Listen Later Dec 17, 2022


    Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Ben Chestnut is the Co-Founder of Mailchimp, the all-in-one marketing platform for small businesses. Last year, in Sept 2021 it was announced that Intuit would acquire Mailchimp for a reported $12BN. There are so many things to love about the Mailchimp journey to this point. First, Mailchimp was founded as the result of a side project of a design agency Ben and his co-founder, Dan, used to run. Second, Mailchimp is and has always been based in Atalanta, eschewing the notion you have to be in SF or NYC to build a massive business. Then third, they never raised venture funding for the business all the way until their $12BN acquisition. Ben led Mailchimp to over 1,200 employees and millions of global users. In Today's Episode with Ben Chestnut We Discuss: 1. From Mama's Kitchen to the Smell of Business and Founding Mailchimp: How did Ben turn a mediocre agency into the founding of Mailchimp? What was the a-ha moment? At what stage of the business did Ben quit the agency and go all in on Mailchimp? What sign did he need that Mailchimp had true product-market fit? When Ben's mother died, he bought every flower in the local town to commemorate her. How did Ben's mother impact the type of father and husband he is today? How did she impact the way that he led Mailchimp as CEO? Ben's fishing trips with his father played a big role in his early years, what were the single biggest lessons for Ben from his fishing trips with his father? 2. Ben Chestnut: The Leader: How does Ben define the term "high performance" in leadership? What does Ben mean when he says "the secret to happiness is to stay in your lane"? Why would Ben describe himself as the "leader of the misfits"? How did that early experience and labeling impact both the people he hired and the culture he created at Mailchimp? What does Ben mean when he says he used to have a "hands off, eyes off" leadership style? What have been the single biggest drivers in his development as a leader? 3. Ben Chestnut: The Person: Relationship to Money: How does Ben reflect on his relationship to money? How has it changed over time? Why does Ben still to this day buy lottery tickets with his wife? Conquering Fatherhood: What does being a great father to Ben mean? How does Ben attempt to instil the same work ethic and drive when his children are born into immense wealth? The secret to Marriage: What does Ben believe is the core to a successful and thriving marriage? How does Ben view his role in the marriage? How has it changed over time? Potential Lost Identity: A founder's identity is so closely tied to their company, how did Ben manage the challenge of selling his company but retaining his identity? What did Ben learn about himself through many different acquisition processes? 4. Mailchimp: The Business: Why did Ben never raise venture money in the 21 year journey of Mailchimp? Why did Ben never accept any of the acquisition offers that came before Intuit? How did Ben motivate his team after they knew each acquisition offer was being turned down? Why did Ben decide the acquisition by Intuit was the right decision for the company? How does Ben view his role in the company now and moving forward?

    #078 Resistance training for time efficiency, body composition, and maximum hypertrophy | Brad Schoenfeld, Ph.D.

    Play Episode Listen Later Dec 17, 2022


    Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Dr. Brad Schoenfeld is a professor at Lehman College in the Bronx, in New York City. His research primarily focuses on muscle adaptations to strength training, muscle hypertrophy. Publishing over 300 studies in the field of exercise and sports nutrition as a scientist, Brad began his career as a competitive bodybuilder and personal trainer. In this episode, we discuss: 05:26 - Why should we lift weights? 06:56 - Why building bone matters 11:33 - How to lift in old age 13:45 - Why to lift while young (especially women) 16:21 - Should children lift weights? 17:05 - Does lifting stunt growth? 19:48 - How to change body composition 27:22 - Protein requirements 29:19 - How to calculate protein needs 36:54 - Protein per meal - what's the right amount? 38:18 - Does time-restricted eating undermine hypertrophy? 43:19 - Anabolic window: myths vs. reality 46:15 - Total daily protein intake 54:49 - Why aging affects muscle power (loss of type II fibers) 57:52 - Power training vs. strength 59:20 - Benefits of explosive power training (fall prevention) 01:03:18 - How to power train with plyometrics 01:03:58 - Training to failure (is it important?) 01:09:59 - Rest in between sets (is it needed?) 01:11:12 - Number of sets per week 01:22:31 - Tips for recovery 01:33:41 - Should you get sore from exercise? 01:36:47 - What can you do for soreness? (without blunting hypertrophy) 01:40:16 - Does aerobic exercise undermine resistance training? 01:44:46 - Resistance training for endurance athletes 01:46:33 - Can stretching increase muscle growth? 01:51:06 - Is yoga a type of resistance training? 01:53:37 - Blood-flow restriction training 01:58:37 - What is Brad's routine? Watch this episode on YouTube Show notes are available by clicking here Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/premium Learn more about the premium podcast The Aliquot: https://www.foundmyfitness.com/aliquot

    Stanley Druckenmiller, the #1 investor in the world – See the future differently

    Play Episode Listen Later Dec 17, 2022


    How Leaders Lead with David Novak ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Welcome to How Leaders Lead where every week, you get to listen in while I interview some of the VERY best leaders in the world. I break down the key learnings so that by the end of the episode, you'll have something simple you can apply as you develop into a better leader. That's what this podcast is all about! Today's guest is Stanley Druckenmiller, the #1 investor in the world. I know, that's a big claim! But get this: during his 30 years managing money for investors, he had an average annual return of 31%. And he NEVER had a down year. So if you're even a little interested in finance, you're going to learn a lot from Stan – including some really practical investment advice and his take on the future of our economy. But more importantly, there's a huge leadership lesson to learn. Stan isn't afraid to envision the future differently than other people. He can see trends and patterns others can't – and then he has the courage to act on them. That's a skill EVERY leader needs to develop. Seeing the future differently allows us to spot opportunities and prepare for what's coming. If we just go with the flow of what's current, we'll always just be a part of the trend, not ahead of it.  You're about to see for yourself how great leaders aren't afraid to see the future differently. So here is my conversation with my good friend, and soon to be yours, Stanley Druckenmiller.

    #40 - Samo Burja

    Play Episode Listen Later Oct 17, 2022


    LABOSSIERE PODCAST ✓ Claimed : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Samo Burja is the founder of Bismarck Analysis, a consulting firm that investigates the political and institutional landscape of society. He's also a Research Fellow at the Long Now Foundation where he studies how institutions can endure for centuries and millennia.Samo is also Senior Research Fellow in Political Science at the Foresight Institute, where he advises how institutions can shape the future of technology.He writes and speaks on history, institutions, and strategy with a focus on exceptional leaders that create new social and political forms. He's systematized this approach as “Great Founder Theory.”

    Joe Rogan interviews Steve Jobs

    Play Episode Listen Later Oct 17, 2022


    podcast.ai ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday ---------

    You Can't Not Think It | 12 Stoic Lessons From Las Vegas

    Play Episode Listen Later Oct 16, 2022


    The Daily Stoic: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday ---------

    Entrepreneur's Paradise | Coolio (Redux)

    Play Episode Listen Later Oct 16, 2022


    James Altucher Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- After the unexpected and untimely passing of Coolio, we have decided to re-air this early episode of the podcast.From the original release notes:"Grammy Award-winning and multi-platinum artist Coolio joins The James Altucher Show to share his story of success. With more than 30 million records sold globally, Coolio gives a side to his story that most people don't know. Teacher? Psychologist? Author? There are many surprising career paths that Coolio he had interests in pursuing.You'll hear how his love of music and his ability to understand and connect with people enabled him to create hip-hop poetry unlike anyone else. Something that most people don't realize is that one of Coolio's biggest hits, “Gangsta's Paradise,” caused him some career conflicts, and here you get all the details.What is truly inspiring is his passion for life and his ability to choose himself. From a rough childhood and being bullied to creating his career from scratch, you get the exclusive details from Coolio himself.He is living proof that believing in yourself is a skill, one that everyone can master if they put their mind to it."------------Visit Notepd.com to read our idea lists & sign up to create your own!My new book Skip the Line is out! Make sure you get a copy wherever books are sold!Join the You Should Run for President 2.0 Facebook Group, where we discuss why you should run for President.I write about all my podcasts! Check out the full post and learn what I learned at jamesaltucher.com/podcast.------------Thank you so much for listening! If you like this episode, please rate, review, and subscribe to “The James Altucher Show” wherever you get your podcasts: Apple PodcastsStitcheriHeart RadioSpotifyFollow me on Social Media:YouTubeTwitterFacebook

    Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring | Episode 93

    Play Episode Listen Later Oct 12, 2022


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, my guest is Nolan Williams, M.D., a triple board-certified psychiatrist, neurologist and professor of psychiatry and behavioral sciences at Stanford School of Medicine. He is also the Director of the Stanford Brain Stimulation Lab. We discuss clinical applications for brain stimulation, behavioral protocols and novel drug treatments to halt and reverse mental health disorders, including depression and post-traumatic stress disorder (PTSD). We first discuss the neural circuits for self-identity and mood and stress control. We discuss Dr. Williams' work using transcranial magnetic stimulation (TMS) to depression, trauma, PTSD, and other mood disorders. We then dive deep into the history, biology, modern use, and safety margins of the various psychedelics, including MDMA, LSD, ketamine, ibogaine, ayahuasca, and psilocybin, as well as cannabis and the use of SSRIs in both adults and children. Finally, we discuss behavioral treatments for mental health disorders, including sleep and sleep deprivation, light exposure, exercise, and training to control the brain-heart-rate pathways. Regardless of age, all those interested in mental health should benefit from the incredible breadth and depth of Dr. Williams' knowledge and the clarity with which he conveys that information. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Nolan Williams, Brain Stimulation & Depression Treatment (00:03:31) Huberman Lab Premium (00:04:42) InsideTracker, Eight Sleep, ROKA (00:08:37) Momentous Supplements (00:09:16) Depression, Risk Factors, Emergency Psychiatric Treatments (00:15:11) The Brain-Heart Connection, Vagus Nerve, Prefrontal Cortex (00:17:51) Right vs. Left Brain Hemispheres & Mood Balance, Connectome (00:22:34) Heart Rate & Depression, Behavioral Interventions, Transcranial Magnetic Stimulation (TMS) (00:33:02) Prefrontal Cortex & Cognitive Control, TMS (00:37:46) AG1 (Athletic Greens) (00:39:00) Belief/Identity “Rules”, Re-scripting, TMS & Talk Therapy (00:45:49) Dorsolateral Prefrontal Cortex, TMS & Depression Treatment (00:48:36) Cingulate Cortex & Emotion, Dissociation & Catatonia (00:54:27) Ketamine, the Opioid System & Depression; Psychedelic Experience or Biology? (01:03:42) SSRIs, Serotonin & Depression; Childhood, Chemical Imbalance or Circuit? (01:13:58) Memories & “Rule” Creation; Psilocybin & “Rule” Resolution (01:21:00) MDMA & Post-Traumatic Stress Disorder (PTSD) Treatment, Psilocybin & Depression Treatment (01:24:12) Is MDMA Neurotoxic?, Drug Purity, Dopamine Surges, Post-MDMA Prolactin (01:30:38) Psilocybin, Brain Connectivity & Depression Treatment (01:34:53) Exposure Response Prevention: “Letting Go” & Depression Treatment (01:41:23) Normal Spectrums for Mental Health Disorders (01:45:35) Ibogaine & “Life Review”; PTSD, Depression & Clinical Trials (01:57:16) Clinical Use of Psychedelics (02:01:59) Ayahuasca, Brazilian Prisoner Study (02:06:55) Cannabis: THC, CBD & Psychosis, Clinical Uses (02:14:52) Personal Relative Drug Risk & Alcohol (02:20:42) Circadian Reset for Depression, Sleep Deprivation, Light (02:28:43) Stanford Neuromodulation Therapy (SNT) Study (02:34:25) Space Learning Theory & TMS Stimulation (02:45:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer

    The Effects of Cannabis (Marijuana) on the Brain & Body | Episode 92

    Play Episode Listen Later Oct 8, 2022


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one's propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Cannabis (Marijuana) (00:04:46) New: Huberman Lab Premium (00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety (00:10:08) Levels, Thesis, InsideTracker (00:14:01) Momentous Supplements (00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD (00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects (00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains (00:30:41) AG1 (Athletic Greens) (00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1) (00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence (00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function (00:53:07) Biological Effects of Cannabis (00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia (01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage (01:09:41) Brain Areas Affected by THC & CBD, Side Effects (01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine (01:26:41) Does Cannabis Increase Creativity? (01:35:08) Chronic Cannabis Use & Changes in Speech Patterns (01:46:46) Cannabis & Libido, Dopamine & Prolactin (01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility (02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences (02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development (02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance (02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis (02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders (02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis (02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

    E98: Big tech starts making cuts, Fed incompetency, global debt, Russia/Ukraine & more

    Play Episode Listen Later Oct 8, 2022


    All-In with Chamath, Jason, Sacks & Friedberg: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- 0:00 Bestie intros! 1:36 Big tech starts making cuts, plus what this means for the broader economy and startups 31:09 Global debt numbers, Fed incompetency 54:06 RIP Coolio 1:00:30 Russia / Ukraine update Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://www.bloomberg.com/news/articles/2022-09-29/meta-announces-hiring-freeze-warns-employees-of-restructuring https://www.google.com/finance/quote/META:NASDAQ https://www.google.com/finance/quote/AAPL:NASDAQ https://www.google.com/finance/quote/GOOG:NASDAQ https://www.cnbc.com/2022/09/28/stanley-druckenmiller-sees-hard-landing-in-2023-with-a-possible-deeper-recession-than-many-expect.html https://www.google.com/finance/quote/NFLX:NASDAQ https://www.mckinsey.com/capabilities/mckinsey-digital/our-insights/if-youre-going-to-build-something-from-scratch-this-might-be-as-good-a-time-as-in-a-decade https://www.forbes.com/sites/jonathanponciano/2021/05/11/billionaire-investor-druckenmiller-blasts-feds-radical-stimulus-policy-warns-it-risks-stock-bubble-blowing-up https://www.cnbc.com/2022/09/28/cnbc-transcript-duquesne-family-office-chairman-ceo-stanley-druckenmiller-speaks-with-cnbcs-joe-kernen-live-during-the-cnbc-delivering-alpha-conference-today.html https://www.xe.com/currencycharts/?from=GBP&to=USD&view=1M https://www.bls.gov/charts/job-openings-and-labor-turnover/unemp-per-job-opening.htm https://fred.stlouisfed.org/series/JTSJOL https://www.wsj.com/articles/a-nation-of-quitters-great-enabling-exodus-working-age-men-parents-stimulus-covid-quit-retirement-bohemian-videogame-11664112795 https://goop.com/subscribe https://www.reuters.com/world/putin-host-kremlin-ceremony-annexing-parts-ukraine-2022-09-29 https://www.reuters.com/world/europe/zelenskiy-says-ukraine-applying-nato-membership-2022-09-30 https://www.reuters.com/world/europe/qa-nord-stream-gas-sabotage-whos-being-blamed-why-2022-09-30 https://www.aa.com.tr/en/economy/former-polish-foreign-minister-thanks-us-for-damaging-nord-stream-pipeline/2696530 https://www.theamericanconservative.com/should-america-go-all-in-on-ukraine

    #220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.

    Play Episode Listen Later Oct 8, 2022


    Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Celia Morgan is a Professor of Psychopharmacology at the University of Exeter who has authored numerous publications on the potential therapeutic uses of ketamine in mental healthcare. In this episode, Celia dives deep into the neurobiology of ketamine, how it affects users, and how it differs from other, more classical psychedelics (LSD, MDMA, PCP, and psilocybin). She explains the potential promise of ketamine as a treatment for recalcitrant depression and addiction, and she details the results from her clinical trials in these areas. She discusses the importance of using ketamine in combination with psychotherapy to maximize its benefits, the potential risks associated with ketamine use, and advice for those interested in the therapeutic use of ketamine. We discuss: Celia's training and interest in ketamine [2:15]; The history of ketamine, medical uses, and use as a party drug [3:30]; Neurobiology and pharmacology of ketamine [8:15]; Ketamine regulation and abuse, and how it compares with psychedelics and other molecules [18:15]; Ketamine as a therapeutic for depression [30:45]; The brain under the influence of ketamine and theoretical mechanisms for its anti-depressive effects [48:00]; Risks and concerns with overusing ketamine, and what an intermittent or maintenance dose might look for a patient [57:15]; Treating addiction with ketamine: Celia's studies of alcohol dependance [1:04:00]; Advice for people considering the therapeutic use of ketamine [1:19:45]; More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    Controversial Business Lessons From Napoleon, Edison, & Hitler | Ben Wilson on My First Million with Sam Parr #369

    Play Episode Listen Later Oct 4, 2022


    My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Episode 369: Sam Parr (@TheSamParr) and Producer Ben (@BenWilsonTweets) take a turn with One Question Friday... instead of a question they discuss traits of conquerors from yesterday and today. ----- Links: * My First Million * How To Take Over The World * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ------ Show Notes: (02:25) - lessons from Hitler (10:45) - lessons from Edison (10:25) - addictive personalities (18:10) - charismatic people (26:25) - bias to action ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

    #532 - Catherine Salmon - Do We Know What Turns Women On?

    Play Episode Listen Later Oct 4, 2022


    Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Catherine Salmon is an evolutionary psychology researcher, professor of Psychology at the University of Redlands and an author. Women can be a mystery, sometimes even to themselves. Modern culture is making many proclamations about what women like and why they should like it, but are these new headlines accurate, or even desirable? Expect to learn why women love erotic stories so much, whether evolutionary psychology is sexist, why Catherine did a study where people rated the attractiveness of faces which had jizz on them, why feminine men are being pushed in media but don't feature in dark romance novels, the role of commitment in female attraction and much more... Sponsors: Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied) Get $100 off plus an extra 15% discount on Qualia Mind at https://neurohacker.com/modernwisdom (use code MW15) Get 5 Free Travel Packs, Free Liquid Vitamin D and Free Shipping from Athletic Greens at https://athleticgreens.com/modernwisdom (discount automatically applied) Extra Stuff: Follow Catherine on Twitter - https://twitter.com/CatherineSalmon  Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/ 

    Erik Hoel on Effective Altruism, Utilitarianism, and the Repugnant Conclusion

    Play Episode Listen Later Oct 4, 2022


    Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Neuroscientist Erik Hoel talks about why he is not an "effective altruist" with EconTalk host, Russ Roberts. Hoel argues that the utilitarianism that underlies effective altruism--a movement co-founded by Will MacAskill and Peter Singer--is a poison that inevitably leads to repugnant conclusions and thereby weakens the case for the strongest claims made by effective altruists.

    Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating | Episode 91

    Play Episode Listen Later Oct 2, 2022


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- My guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern's research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson's disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation (00:03:18) ROKA, Eight Sleep, InsideTracker (00:07:19) Momentous Supplements (00:08:28) Neurosurgeon's View of the Brain, Neurosurgery Specialization (00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects (00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies (00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction (00:31:11) AG1 (Athletic Greens) (00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition (00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity (00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation (00:49:49) Binge Eating Disorder & Loss of Control Eating (00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress (01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells” (01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation (01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia (01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation (01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson's (01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression (01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation (01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions (01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts (01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training (02:09:53) Daily Habits: Sleep, Exercise, Mediation (02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

    Expected Returns for Alternative Asset Classes (plus Reading Habits w/ David Senra) (EP.219)

    Play Episode Listen Later Oct 1, 2022


    The Rational Reminder Podcast ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- The type of assets which usually come to mind when considering investments are stocks, bonds, or cash, but what are the alternatives? And what kind of returns do alternative asset classes offer? In today's episode, we delve into the returns which can be expected from alternative asset classes such as private equity, venture capital, angel investing, private credit, hedge funds, direct real estate, and cryptocurrencies. Hear an in-depth analysis based on empirical studies and the expertise of your hosts, Ben and Cameron, to discover whether there is any merit to alternative asset classes as investments. We unpack the extra layer of complexity associated with predicting returns on alternative assets, how to approach calculating returns, and why the associated fees are an essential consideration. We also hear details about an interesting conference Cameron recently attended and briefly recap cryptocurrencies as an investment. You'll also hear our conversation with our 22 in 22 reading challenge guest David Senra about his reading habits, the books that most inspire him, and his advice for people who want to read more.   Key Points From This Episode:   Outline of today's main topic: expected returns for alternative asset classes. (0:01:51) Why predicting returns of alternative asset classes has an extra layer of complexity. (0:03:18) How to approach estimating the returns of private equity, specifically buyouts. (0:05:04) We unpack historical data regarding the returns of private equity. (0:07:35) Calculating the returns on venture capital and reasons to be cautious about it as an asset class. (0:16:35) The distribution of returns from venture capital based on the market numbers. (0:20:09) Learn what angel investing is and its associated returns. (0:20:54) What returns on angel investing are most dependent on and why. (0:22:21) The different types and the associated returns. (0:25:23) Hear about the fees associated with private credit. (0:27:42) We unravel the concept of hedge funds, the associated fees, and expected returns. (0:29:29) A limiting factor on hedge funds: capacity constraints. (0:33:38) The takeaway regarding private real estate investments. (0:36:25) How private real estate is valued as an asset class. (0:37:48) Cryptocurrencies and the returns to be expected. (0:39:34) We discuss some of the key takeaways from today's main topic. (0:43:30) We follow up on a previous topic we covered: financial literacy. (0:45:10) Find out about an interesting conference that Cameron recently attended. (0:48:46) Hear about the recent reviews we have received about the podcast. (0:57:58) We introduce our 22 and 22 reading challenge guest, David Senra. (01:00:15) Where David's passion for reading about founders originates from. (01:02:25) David shares details about his reading habits. (01:05:57) His approach to finding founders that he wants to read about. (01:08:49) David's approach to note taking while reading a book. (01:11:07) We learn about the stories that have impacted David the most. (01:13:53) He explains the benefits of reading a book for a second time. (01:17:11) Books about founders that he thinks everyone should read. (01:19:20) David's observation of the role of luck in a founder's success story. (01:23:19) Advice he has for people who want to read more. (01:29:33)   Links From Today's Episode:   AQR Capital Management — https://www.aqr.com/ BlackRock Asset Management — https://www.blackrock.com Bank of America — https://www.bankofamerica.com/ ‘The risk and return of venture capital' — https://www.sciencedirect.com/science/article/pii/S0304405X04001564 ‘Performance of Private Credit Funds: A First Look' — https://jai.pm-research.com/content/21/2/31.short ‘Do Hedge Funds Hedge?' — https://jpm.pm-research.com/content/28/1/6.short ‘The Performance of Hedge Fund Performance Fees' — https://www.nber.org/papers/w27454 ‘Higher risk, lower returns: What hedge fund investors really earn' — https://www.sciencedirect.com/science/article/abs/pii/S0304405X1100016X ‘Another Look at Private Real Estate Returns by Strategy' — https://jpm.pm-research.com/content/45/7/95/tab-pdf-trialist 'The Characteristics and Portfolio Behavior of Bitcoin Investors: Evidence from Indirect Cryptocurrency Investments' — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3501549 ‘Beliefs and the Disposition Effect' — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3516567 ‘Once Bitten, Twice Shy: The Power of Personal Experiences in Risk Taking' — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2506627 S&P Global FinLit Survey — https://gflec.org/initiatives/sp-global-finlit-survey/ Future Proof Conference — https://futureproof.advisorcircle.com/ Invest Like the Best Podcast — https://investlikethebest.libsyn.com/ David Senra on LinkedIn — https://www.linkedin.com/in/david-senra-278843236/ David Senra on Twitter — https://twitter.com/FoundersPodcast?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor David Senra on Facebook — https://www.facebook.com/david.senra.1 The Founders Podcast — https://founders.simplecast.com/ A Triumph of Genius — https://www.amazon.com/Triumph-Genius-Edwin-Polaroid-Patent/dp/1627227695 Cable Cowboy — https://www.amazon.com/Cable-Cowboy-Malone-Modern-Business/ Titan — https://www.amazon.com/Rare-Chernow-Titan-Life-Rockefeller/ A Man for All Markets — https://www.amazon.com/Man-All-Markets-Street-Dealer/ Against the Odds — https://www.amazon.com/Against-Odds/ Estee: A Success Story — https://www.amazon.com/Estee-Success-Story-Lauder/ Rational Reminder on iTunes — https://itunes.apple.com/ca/podcast/the-rational-reminder-podcast/id1426530582. Rational Reminder Website — https://rationalreminder.ca/ Rational Reminder on Instagram — https://www.instagram.com/rationalreminder/?hl=en Rational Reminder on YouTube — https://www.youtube.com/channel/ Ben Felix — https://www.pwlcapital.com/author/benjamin-felix/ Ben on Twitter — https://twitter.com/benjaminwfelix Ben on LinkedIn — https://www.linkedin.com/in/benjaminwfelix/ Cameron Passmore — https://www.pwlcapital.com/profile/cameron-passmore/ Cameron on Twitter — https://twitter.com/CameronPassmore Cameron on LinkedIn — https://www.linkedin.com/in/cameronpassmore/  

    #147 Reid Hoffman: Better Decisions, Fewer Mistakes

    Play Episode Listen Later Oct 1, 2022


    Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Few figures have shaped the way we think about business over the past 20 years more than Reid Hoffman. The co-founder of LinkedIn and former PayPal executive is also a wildly successful venture capitalist, author and podcaster, but he didn't get to his place as a Silicon Valley giant without making plenty of crucial decisions. On this episode Hoffman discusses lessons learned from decades spent as a hands-on operator and investor, including what he knows about scaling that others miss, the three principles of decision making, how to constantly evolve your learning pattern, and why the best leaders adapt to the crisis at hand. Hoffman is perhaps best known for co-founding the professional networking site LinkedIn, which he started in 2003 and later sold for a reported $26.2 billion to Microsoft in 2016. Prior to founding LinkedIn, Hoffman was one of the first employees at PayPal, where he served as an executive vice president. He is also a partner at the venture capital firm Greylock Partners, an investor in Airbnb, the author of a series of successful business books including Masters of Scale, and the host of the podcast of the same name. Want to hear the entire episode with Reid Hoffman? Become a member today! Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/ Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/ Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

    Nicotine's Effects on the Brain & Body & How to Quit Smoking or Vaping | Episode 90

    Play Episode Listen Later Sep 24, 2022


    Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I explain how nicotine impacts the brain and body, including its potent ability to enhance attention, focus, and alertness, increase blood pressure and metabolism and reduce appetite. I discuss nicotine's ability to increase the action of neurochemicals, including dopamine, norepinephrine, and acetylcholine and activate sympathetic (alertness-promoting) neural circuits. I also discuss common nicotine delivery methods, such as cigarettes, vaping, dip, and snuff, and how they each create their own unique experience and how they, but not nicotine itself, cause cancer and other adverse health effects. I also explain science-based tools to permanently quit smoking cigarettes or vaping, including peer-reviewed clinical hypnosis tools, antidepressants, and alternative nicotine replacement (patches, lozenges, gums etc.). As nicotine is one of the most widely used substances with billions of users — most of whom report wanting to quit — this episode ought to be of interest to former/current nicotine users, those who want to quit smoking or vaping and/or those interested in learning the biology behind how nicotine impacts the brain and body. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Nicotine (00:02:47) Momentous Supplements (00:03:41) Tool: Brief Daily Meditation & Focus (00:05:59) The Arrow Model of Focus, Alpha GPC & Garlic Supplements (00:10:43) Thesis, InsideTracker, ROKA (00:14:35) Nicotine Effects vs. Methods of Delivery, Acetylcholine (00:19:55) Where is Nicotine Found? Nicotinic Acetylcholine Receptors (00:25:12) Nicotine & Effects on the Brain: Appetite, Dopamine & GABA (00:30:58) AG1 (Athletic Greens) (00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting” (00:37:29) Nicotine, Norepinephrine & Alertness/Energy (00:41:10) Nicotine & Effects on Appetite & Metabolism (00:46:47) Nicotine & Effects on Body: Sympathetic Tone (00:51:29) Nicotine & Cognitive Work vs. Physical Performance (00:55:08) Nicotine Delivery Methods & Side Effects, Young People & Dependency (00:58:35) Smoking, Vaping, Dipping & Snuffing: Carcinogens & Endothelial Cells (01:02:34) Smoking, Vaping, Dipping & Snuffing: Negative Impacts on Lifespan & Health (01:09:23) How to Quit Smoking, Nicotine Cravings & Withdrawal (01:13:56) Vaping & Nicotine, Rates of Effect Onset, Dopamine, Addiction & Depression (01:25:06) Tool: Quitting Smoking & Clinical Hypnosis, Reveri (01:30:16) Bupropion (Wellbutrin) & Quitting Smoking (01:36:24) Tool: A Nicotine Replacement Schedule to Quit Smoking, Nicotine Patch/Gum (01:41:52) Tool: Biological Homeostasis & Nicotine Withdrawal, The “First Week” Strategy (01:51:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook Title Card Photo Credit: Mike Blabac Disclaimer

    #516 - Gurwinder Bhogal - 16 Surprising Psychology Truths

    Play Episode Listen Later Sep 24, 2022


    Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Gurwinder Bhogal is a programmer and a writer. Gurwinder is one of my favourite Twitter follows. He's written yet another megathread exploring human nature, cognitive biases, mental models, status games, crowd behaviour and social media. It's one of the best things I've read this year, so I just had to bring him on. Expect to learn how bad things can sometimes feel better than good things, why people die on the hill of opinions they've only just begun believing, why intelligence plus ideology is a nightmare, how comedy can be a troll's last line of defence, the biggest lesson I learned from Joe Rogan, why regret minimisation should be a priority, why authoritarians lose sight of rationality and much more... Sponsors: Get over 37% discount on all products site-wide from MyProtein at https://bit.ly/proteinwisdom (use code: MODERNWISDOM) Get 20% discount & free shipping on your Lawnmower 4.0 at https://www.manscaped.com/ (use code MODERNWISDOM) Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied) Extra Stuff: Check out Gurwinder's Substack - https://gurwinder.substack.com/ Follow Gurwinder on Twitter - https://twitter.com/G_S_Bhogal Gurwinder's new MegaThread - https://twitter.com/G_S_Bhogal/status/1545510413982474253  Adam Mastroianni's post - https://experimentalhistory.substack.com/p/underrated-ideas-in-psychology  Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/ 

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