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The Philip DeFranco Show
PDS 1.24 Truth About Idubbbz & Creator Clash 2, Taylor Swift Ticketmaster Anti Hero, M&Ms, & More

The Philip DeFranco Show

Play Episode Listen Later Jan 24, 2023 18:51


Go to https://sbird.co/3GjowXg and use code DEFRANCO to get 55% OFF your first month's sample! Catch Up on Yesterday's Show here: https://youtu.be/1Eh3P80vpAk Check Out Sunday's Show: https://youtu.be/o-44S-4ki54 – 00:00 - Creator Clash 2 Lineup Released 02:38 - Senators Hold Hearing into Ticketmaster and Live Nation 06:55 - Maya Rudolph Replaces M&M Spokescandies 09:23 - Sponsored by Scentbird 10:19 - Farm Group Says Egg Prices Are Rising Because of a “Collusive Scheme” 12:52 - NYPD Responds to Backlash After Filming People Exiting Drake Concert 14:05 - NATO Talks Between Turkey and Sweden Get Heated 15:06 - More Tragedy Hits California Communities – This month I received... Colonia C.L.U.B. by Acqua di Parma https://sbird.co/3GfkFdL HOS N. 004 by House Of Sillage https://sbird.co/3WIcRIq Charmer by English Laundry https://sbird.co/3IsTej0 Stag by The Maker https://sbird.co/3VH9Eaw Vanilla Embers by Eauso Vert https://sbird.co/3CiGI1Z African Leather by Memo Paris https://sbird.co/3Cgb5Gk – ✩ TODAY'S STORIES ✩ Creator Clash 2 Lineup Released: https://dotesports.com/streaming/news/creator-clash-2-releases-stacked-12-bout-fight-card Senators Hold Hearing into Ticketmaster and Live Nation: https://roguerocket.com/2023/01/24/live-nation-ticketmaster-hearing/ Full hearing: https://youtu.be/9AnR1L1wV-4 Maya Rudolph Replaces M&M Spokescandies: https://time.com/6249551/m-m-candy-mascots-culture-wars/ Farm Group Says Egg Prices Are Rising Because of a “Collusive Scheme:” https://www.cnbc.com/2023/01/23/high-egg-prices-due-to-a-collusive-scheme-by-suppliers-group-claims.html NYPD Responds to Backlash After Filming People Exiting Drake Concert: ​https://www.cbsnews.com/newyork/news/nypd-says-officer-seen-outside-drake-at-the-apollo-was-taking-video-for-social-media/ NATO Talks Between Turkey and Sweden Get Heated: https://www.bbc.com/news/world-europe-64261617 More Tragedy Hits California Communities: https://roguerocket.com/2023/01/24/half-moon-bay-oakland-california/ —————————— Produced by: Cory Ray Edited by: James Girardier, Julie Goldberg, Maxwell Enright, Christian Meeks Art Department: William Crespo Writing/Research: Philip DeFranco, Maddie Crichton, Lili Stenn, Brian Espinoza, Chris Tolve, Star Pralle ———————————— #DeFranco #iDubbbz #TaylorSwift ————————————

ASCO eLearning Weekly Podcasts
Cancer Topics - My Approach to Refractory Diffuse Large B-Cell Lymphoma

ASCO eLearning Weekly Podcasts

Play Episode Listen Later Jan 18, 2023 26:47


Diffuse Large B-Cell Lymphoma or DLBCL is the most common type of lymphoma. Much progress has been made in treatment of the disease lately, particularly with emergence of CAR T-cell therapy, but not all patients are benefiting from it. This episode of Cancer Topics features Drs. Loretta Nastoupil and Chijioke Nze exploring treatment approaches for two cases of refractory DLBCL: a 60-year-old man with no comorbidities (1:30) and a 39-year-old woman with HIV (18:35). The guests also discuss improving patient access to CAR T-cell therapy and managing its toxicities (10:35), as well as emerging therapies for DLBCL (14:30). To learn more about management of refractory DLBCL, check out the ASCO course linked bellow. Guest Disclosures:Loretta Nastoupil, MD: Honoraria – Gilead Sciences, Novartis, Bayer, Janssen Oncology, TG Therapeutics, Bristol-Myers Squibb, ADC Therapeuitcs, Morphosys, Epizyme, Genmab, Takeda, Genentech/Roche; Research Funding – Janssen Biotech, Celgene, Genentech/Roche, Epizyme, Novartis, IgM Biosciences, Caribou Biosciences, Gilead Sciences, Allogene Therapeutics, Takeda Chijioke Nze, MD, MPH: No Relationships to Disclose Resources: ASCO Course: Second-line Therapy for Relapsed/Refractory Diffuse Large B-cell Lymphoma (Free to Full and Allied ASCO Members) ASCO Podcast: Cancer Topics - New Therapies for Lymphoma (Part 1) ASCO Guideline: Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor (CAR) T-Cell Therapy ASCO Article: Navigating the Evolving Treatment Landscape of Diffuse Large B-Cell Lymphoma If you liked this episode, please follow the show. To explore other educational content, including courses, visit education.asco.org. Contact us at education@asco.org.  TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Loretta Nastoupil: So, I do have optimism that as we have more and more treatment options entering into the treatment landscape, we'll have fewer patients that are experiencing a refractory disease, and potentially succumbing to the lymphoma. Hello, my name is Dr. Loretta Nastoupil, I'm an Associate Professor and Deputy Chair of the Department of Lymphoma and Myeloma, at the University of Texas MD Anderson Cancer Center. Welcome to this ASCO Education podcast episode. It's my pleasure to welcome Dr. Chijioke Nze. Dr. Chijioke Nze: Hello, everyone. I'm Dr. Chijioke Nze, a Hematology/Oncology fellow at MD Anderson, I'll be co-hosting this episode with Dr. Nastoupil. Dr. Loretta Nastoupil: We've seen notable advances in diffuse large B-cell lymphoma research lately, with novel treatments including CAR T-cell therapy, offering the prospect of long-term remission for some patients, yet many patients are not even receiving second-line or later therapy, and even fewer are treated beyond the second line. How do you approach a patient with refractory diffuse large B-cell lymphoma? In today's episode, we'll explore strategies for management of refractory diffuse large B-cell lymphoma through two patient cases. So, Dr. Nze, walk us through our first case. Dr. Chijioke Nze: Our first case is Frank. Frank is 60 years old and has no comorbidities. He presented with severe back pain in September 2021, and was evaluated locally. He had a CT scan that showed retroperitoneal mass, prompting further evaluation. He had a biopsy of the left retroperitoneal mass in November 2021, which was consistent with diffuse large B-cell, germinal center B-cell of phenotype Ki-67 of 90%. He had a subsequent PET-CT scan, which showed a large conglomerate, and invasive left retroperitoneal hypermetabolic mass with satellite nodularity and contiguous bulky retroperitoneal adenopathy. He had bulky, FDG-avid metastatic retrocrural and intrathoracic adenopathy as well. He was treated with R-CHOP for six cycles, and at the end, achieved complete remission. He had a PET-CT a year later that showed new and worsening intensely FDG-avid abdominal adenopathy. This was new from a PET scan he'd had in January 2022 of the same year. He had a biopsy of this retroperitoneal adenopathy, which was consistent with relapsed diffuse large B-cell germinal center phenotype, also Ki-67 of 90%. Locally, he was treated with ICE, times five cycles, and had a follow-up CT scan at the end, which showed persistent bulky nodal disease with periaortic regional nodes with double 5, consistent with persistent disease. He also was found to have new and more conspicuous nodes in other areas as well. He presented for his first visit at MD Anderson in September 2022. Dr. Nastoupil, when you see a patient like this coming into your clinic, what's your typical approach? Dr. Loretta Nastoupil: For a diffuse large B-cell lymphoma, we are always hoping for cure with frontline rituximab, containing anthracycline-based chemotherapy. And so, it's always a gross disappointment when patients experience relapse. The timing of that relapse right now informs our current approach. And the reason I mention that, is because there have been three large randomized studies conducted and reported out just in the last year demonstrating that CAR T-cell therapy is the preferred option for patients who experience either primary refractory disease, or relapse within 12 months. And that is because they resulted in better outcomes than standard salvage-based chemotherapy and high-dose therapy autotransplant in the setting of chemosensitive disease. I have to acknowledge, of the three studies that were done, two were positive trials, so that's why currently, we have axi-cel or Axicabtagene ciloleucel, or Lisocabtagene maraleucel, and not tisa-cel or Tisagenlecleucel, as CAR T-cell therapy options. And again, that's because two of the three studies were positive trials. Now, the challenge is why would we have two positive studies in one negative trial? There are a lot of caveats to how those studies were conducted, but I think one of the biggest important lessons to be gained is that if you're going to consider CAR T for these high-risk patients, you want to do it as soon as possible, because that delay from identifying CAR T as a preferred option to actually infusing cells in a disease-- in a case particularly like this, where patients may have bulky, aggressively-behaving disease - that prolonged time may actually have an impact on outcomes. Dr. Chijioke Nze: Excellent. Thank you. So, you've mentioned he had an early relapse. How would you define early relapse in this patient population? Dr. Loretta Nastoupil: Thinking back to how we've been approaching diffuse large B-cell lymphoma over the last two decades, the PARMA study, which was done prior to Rituximab, suggested that for patients who had chemosensitive disease to a platinum-based salvage chemotherapy, which generally, was at least a partial response on CT, if they went on to high-dose therapy autologous stem cell transplant, 50-60% of those patients could anticipate cure. Whereas for the folks who continued on salvage chemotherapy, 10-20% of those patients had favorable outcome. So, we generally do try salvage-based chemotherapy, and for patients with chemosensitive disease, go on to high-dose therapy autotransplant. However, in the modern era where we've approached patients who've had rituximab as part of their frontline therapy, at least two studies - the ORCHARD study, and the CORAL study suggested that only 20% of patients who relapse in the post-rituximab era, particularly within 12 months, were successfully salvaged with platinum-based chemotherapy and high-dose therapy autologous stem cell transplant. Now, fortunately for patients who fail salvage, we have had CAR T-cell therapy as an option based off of three pivotal phase II studies, demonstrating about 40% of patients could anticipate a cure with CAR T-cell therapy. So, it only made sense to try and move that therapy up into second line, and the preferred population was those that had progressed within 12 months of frontline rituximab and anthracycline-based chemo. Now, to qualify for those studies, patients had to be considered fit for the control arm, which was salvage and auto transplant. Nonetheless, I do think for a patient like this, who's 60, without any other significant comorbidities, whose biggest challenge to longevity of life is his aggressive lymphoma, CAR T-cell therapy should be considered as soon as possible for this patient. Dr. Chijioke Nze: Is there still a role for high-dose therapy and autologous transplant in the new era, given the efficacy shown with CAR T-cell therapy? Dr. Loretta Nastoupil: I think there is. And the reason why I say that is, the trials that were done really did focus on the highest-risk patients, which were those with primary refractory disease or those who progress within 12 months of frontline. Now, there are patients that will have later relapse. And so, I do think for those patients, particularly those who are young and otherwise fit, should be approached first with a platinum-based salvage chemotherapy, in the setting of chemosensitive disease, proceed onto high-dose therapy and autologous stem cell transplant. Now, what do we do for those patients who have a late relapse but are otherwise older, or who have comorbidities that would make them suboptimal candidates for the high-dose therapy preceding stem cell transplant? I have a couple other options for those patients - so, there was a trial done with liso-cel for patients who were otherwise older, or not fit for intensive therapy. It's a single-arm phase II without a randomized comparison, but also demonstrated that liso-cel in second-line, later relapsed patients who are not fit for intensive therapy, resulted in comparable outcomes to what we would anticipate on that third-line or later setting. We also have other non-CAR T-cell therapy options, such as tafasitamab, which is a naked CD19 antibody, which has been combined with lenalidomide in the L-MIND study, again, for patients without primary refractory disease and who would not be appropriate candidates for intensive therapy. So, I do think we have alternative options, it's just when we look at the totality of the data right now, my conclusion is that CAR T-cell therapy, particularly for high-risk patients, is the most likely chance to result in cure. Dr. Chijioke Nze: Excellent. In a patient who we are considering CAR T-cell therapy, what are some of the short-term and long-term consequences, or toxicities that we should worry about? Dr. Loretta Nastoupil: One of the challenges right now with CAR T, and why it's still only available in specialized centers, is the acute toxicity, which is really a derivative of its mechanism of action. We take patients' own T-cells, we use a viral vector to introduce extracellular receptor, but also a co-stimulatory molecule. So, once these cells engage their antigen, sort of prime to react to that, and that can lead to pretty rapid T-cell expansion, release of cytokines, recruitment of other inflammatory cells to that tumor bed, and as a result, a large portion of patients can anticipate to experience cytokine release syndrome, which again, is the result of the activation of these T-cells, the expansion and the recruitment of other inflammatory cells. Fortunately, for most patients, this results in fever alone that can be managed with supportive measures. Occasionally, they'll have concomitant hypoxia or hypotension, and unfortunately, few patients will have significant or severe toxicity. The other toxicity that's less easily manageable or less predictable is the neurotoxicity that can vary according to patient-specific characteristics, such as age, and the amount of tumor burden, their performance status going into CAR, but even more importantly, the construct that's utilized, with highest rates of neurotoxicity associated with axi-cel. Again, likely speaking to its construct and the CD28 costimulatory domain that is unique to axi-cel. As a result of these acute toxicities, patients are required to stay within two hours of their treating center for the first four weeks, and they're also discouraged from operating heavy machinery, such as driving, for the first eight weeks following CAR T. So, I do you think this creates some barriers to access to this therapy, particularly the patients that are treated in community settings that may reside long distances from these certified CAR centers. Dr. Chijioke Nze: So, you mentioned that obviously, given the specialized care needed for the CAR T therapy, that they're kind of localized in certain sites. What are some of these issues with access that you're noticing both in the logistics of giving CAR T, and also in patient access? Dr. Loretta Nastoupil: I'm hoping we're going to address one of those issues right now, which is, education and awareness, because we've had these three randomized studies, and two being positive readouts just in the last year. It's important to get the message out that CAR T-cell therapy for high-risk early relapsed refractory large cell lymphoma patients can result in a significant improvement in event-free survival and progression-free survival over the standard of care. And so, being aware that this therapy can result in more favorable outcomes is step one. Step two is, we have to ensure that there are minimal barriers to getting those patients into these treating centers as quickly as possible. So, recognizing who delivers the care - is it your traditional stem cell transplant physician? Is it a lymphoma doctor? What centers are certified? Some of these issues can be addressed with quick internet searches. So, for instance, in our center, we have a 1-800 number for anyone who's interested in CAR T-cell therapy that connects them directly to a CAR T coordinator who can help them understand do they meet the FDA-approved indication? Would they be interested in seeking consult? And we try and prioritize getting those patients in the door as soon as possible since time likely does have an impact on outcomes. And then, partnering with our community oncologist - you're going to be the primary oncologist for these patients leading up to CAR, and then after that four-week window, when we're keeping the patients in close proximity to our centers, we often send them back. And so, making sure that they're comfortable knowing what potential late toxicities to be on the lookout for, which include B-cell aplasia and risk for infection, or prolonged cytopenias, beyond just lymphopenia. And so again, there's a need for education and partnering with our community sites to make sure that there is successful handoff of these patients back after they've completed the monitoring for the acute toxicity. And then, really trying to explore opportunities to utilize some of the better tolerated CAR T, such as liso-cel, in your non-traditional academic centers. Those that are equipped to handle phase I studies or stem cell transplant, for instance, may not be affiliated with the university. So, I think those are all types of strategies that could be employed to try and improve access for patients. Dr. Chijioke Nze: And then, you mentioned the liso-cel, but in some of the toxicities, are there ways of predicting which patients will do better or worse? Are there ways to reduce toxicities? And is there any hope for things such as outpatient administration of CAR T? Dr. Loretta Nastoupil: So, my answer today may improve over time as we get larger numbers and more experience, but what we currently understand is that the patient performance status, their degree of tumor, how quickly that tumor is increasing, LDH and some inflammatory markers such as CRP or ferritin pretreatment can provide some insight into a higher risk of toxicity. And then obviously, the construct that's utilized. Again, axi-cel has higher rates of neurotoxicity. All will have some form of cytokine release syndrome, generally speaking, but rates of grade three or higher are quite infrequent, particularly with liso-cel and tisa-cel. So, it's multifactorial. That then raises the question, can we do anything to alter those modifiable risk factors? Can we reduce the disease burden? Can we improve the performance status? Can we do anything to reduce the inflammatory markers pre-treatment? And so, those are strategies that are being discussed, and I think in general, as we get more effective therapies that enter into the treatment landscape, it's probably some of the best ways to try and reduce some of those risk factors. Dr. Chijioke Nze: Rounding that up, are there any exciting developments or things to look out for, for exciting therapies in the relapse setting? Dr. Loretta Nastoupil: A couple of things beyond CAR T that I think we should all be aware of and anticipate to be in our toolkit relatively soon; probably, one of the most exciting, is the development of the bispecific antibodies. So, another challenge with CAR T is the requirement to collect these patients' own T-cells and send them off to a central manufacturing site, and the turnaround time can be anywhere from 3-4 weeks. And again, in a situation where you have an aggressive disease, that can be a long time to wait. And so, is there any treatments that are more readily available, that again, will be effective at reducing disease burden? And so, by specifics kind of fit those unmet needs to some extent - you have essentially two heads; one head is going to bind the endogenous T-cells that eliminates the need to leukapherese these patients and manufacture, and then the other head is going to generally engage CD20, which we know is an effective targeted antigen, particularly in B-cell lymphomas. And there are a number that are under development. We saw preliminary phase II data with glofitamab, epcoritamab, as well as combination strategies with mosunetuzumab. So, I do have optimism that the bispecific antibodies will potentially enter into the treatment landscape. I anticipate they'll probably be used first post-CAR T, but will likely move their way into earlier lines of therapy. I've already mentioned tafasitamab in combination with lenalidomide, which is an effective non-chemotherapy option. We have antibody-drug conjugates, such as Loncastuximab, which is a CD19 antibody-drug conjugate. It's essentially targeted delivery of chemotherapy, and it looks to have a pretty promising activity as a single agent in that third-line or later space, and then polatuzumab, which is a CD79b antibody drug conjugate, in the relapse setting has been combined with bendamustine and rituximab, but also demonstrated significant improvement in the frontline setting in the POLARIS study where vincristine was replaced with polatuzumab. So, I do have optimism that as we have more and more treatment options entering into the treatment landscape, we'll have fewer patients that are experiencing refractory disease, and potentially succumbing to the lymphoma. Dr. Chijioke Nze: And then, one additional question: How do you approach a patient who is not quite as fit, in thinking about what their options are for later-line therapies? You already mentioned some of these, but which of those would you prioritize in this setting? Dr. Loretta Nastoupil: Again, as we get more experience, we develop skills that help us sort of navigate all these different options. In my practice, if I'm even considering CAR T, I'm going to delay bendamustine until after I've collected those cells. I think that's one caveat that-- we do get nervous about the quality of those autologous CAR Ts if they're generated in someone who's had recent exposure to bendamustine. So, that may help me sequence that later on. We have questions right now about what's the optimal sequencing of CD19-directed therapy because we have several options beyond just CAR T-- As I mentioned, we have Lonca, we've got tafasitamab and lenalidomide. Currently, we don't have prospective data that really informs that question, and there's a number of research studies underway to try and help us understand if there is a preferred sequence, or even if it matters how we handle CD19 targeting. For my older, frailer patients where I'm really worried, they're not going to be able to tolerate something like liso-cel, or they're not going to be able to have that caregiver, and they're uncomfortable relocating to an area where CAR T might be available, my general approach right now is to consider tafasitamab and lenalidomide first in that relapse setting, followed by either Lonca or Pola-BR. Selinexor is another option. It's an oral agent, though again, in my opinion, if we look at the totality of the data, may be less effective than the other options. So, I might reserve that as a last option for someone, again, with relapsed/refractory large cell. Dr. Chijioke Nze: Excellent. Thank you. This has been very helpful. Dr. Loretta Nastoupil: All right. So, Dr. Nze, now I'm going to turn the table and ask you some questions. I'm going to change this up a little bit - she's now a 39-year-old female. She has significant comorbidities. She has HIV, and again, large cell lymphoma. So, let me walk you through her case, and then we'll discuss some of the challenges, again, in a very different scenario, albeit a similar disease. So, our female is, I mentioned 39, pre-existing HIV, she's treated frontline with six cycles of R-CHOP and intrathecal methotrexate for CNS prophylaxis. Because of her comorbidities, again, not well controlled HIV, she also has a poor functional status at the time of relapse. This was a couple years ago, and CAR T was not an option in second line, though she is someone who had a relapse that was beyond 12 months. So, for her second-line approach, because of her comorbidities, she actually receives rituximab in combination with high-dose cytarabine, dexamethasone, and oxaliplatin for three cycles, and actually achieves a chemosensitive disease and is referred to our stem cell transplant colleagues. Unfortunately, at that time, due to comorbidities, she was deemed not to be an appropriate candidate for high-dose therapy, and she's been monitored for signs of relapse. Despite being in the minority, she actually does not have a recurrence of her lymphoma but has a number of other, again, challenges in regards to her comorbidity, including multiple infections, resulting in recurrent hospitalizations. And so, it's always been a challenge for me in being intimately involved in her case, deciding when she's presenting, how alarmed to be about recurrent lymphoma versus infection, and how I might approach her in the setting of relapsed large cell lymphoma. So, what role does prior type and response to therapy play in treatment selection at your next line of treatment? Dr. Chijioke Nze: I think in this patient, it sounds like she got one adequate therapy on and the initial presentation with R-CHOP, and then with IT chemotherapy as well. She looked like she had a good response. I think the fact that she achieved a complete response and the duration of her response, lets me know that she likely has chemosensitive disease. This, in turn, helps me to pick what to do next. As you mentioned previously, we know how efficacious the CAR T therapy is, but in someone like her who had a long duration, trying salvage therapy and proceeding to autologous transplant might make sense. I'd be interested in your thoughts. Dr. Loretta Nastoupil: Yeah, I agree. And I think part of the challenge, particularly when we're facing patients with HIV, they're often excluded from prospective studies. And so, we're often in a scenario where we may not have the wealth of data to inform our treatment decision. But I do think in general, comorbidities play a major role-- we're navigating treatment options. Because again, traditionally, we've used intensive chemotherapy as our mainstay of treatment, and there are clear criteria that patients generally should meet that help us predict how likely they are to have significant or severe toxicity from high-dose therapy. And this is a prime example of even though she was young, her comorbidity made her a poor candidate for intensive therapy. I think the other sort of non-clinical factors that we sometimes take into consideration, because CAR T was approved off of single-arm phase II studies, again, none of which would've included someone like her, because of her HIV status, how do we extrapolate-- for instance, if she had relapsed in that third-line space, and suggesting that she did not have significant infection or other significant comorbidities, do we have experience to proceed with an autologous CAR in that setting? So, again, there've been a few cases where we have case reports where people have reported on their standard of care outcomes, particularly with CAR T in patients with active HIV disease, but one of the concerns I have in these scenarios is very selected. If you have active infection, that can make the acute toxicity with CAR significantly worse. And so again, we're trying to navigate a sort of limited data zone to try and help her and choose the right therapy. Again, you've met this patient with me, you helped care for her for some time, and you have a unique experience of also practicing in a county hospital where comorbidities, particularly, like HIV, can be much more common. What is your perception regarding barriers to accessing CAR T as it pertains to social factors, clinical factors, and again, this is a case that highlights some of those issues. Dr. Chijioke Nze: You mentioned at first that she had uncontrolled HIV. So, I think which, one, speaks to her treatment reference of her non-malignancy-related diseases, and trying to get that under control would be one of the first things I could think about. Thinking about how her care is managed and what kind of support she has are very important for us to think about as well. The other thing that's very important is, a lot of patients who we're seeing in the community may not have access to such specialized centers such as MD Anderson, where patients do have access to clinical trials and CAR T therapy. So, patients who are unlike her, who might qualify, may not actually be able to get these therapies as well. Part of the reason is, it can be insurance status, which is what we see in a lot of our patients. So, a barrier to get into the door. And then too barriers, lack of social support can be a big issue as well. And then there's also a big push in the community to improve the trust and awareness of these novel therapies, as you've mentioned. So, in a lot of the community practice, some of the community practitioners may not be comfortable with these, and a lot of the patients may not have heard of these new technologies, and also want to defer trying new therapies before having other people try new therapies before they consider them themselves. I think all these things present specific significant barriers to patients in the community. One, their ability to adhere to care, two, their insurance and their ability to get care and the financial toxicities associated with that. And then third, really understanding the options that are available. Dr. Loretta Nastoupil: And again, just to try and illustrate a couple other points. You know, we use a case here, which is a real case, with significant comorbidities such as HIV, which again, is something that is not frequently encountered, and will have a large impact on treatment selection. What if I just told you this patient has comorbidities, but she has moderate type-2 diabetes, and as a result, she has mild renal insufficiency, ejection fraction is actually adequate, would you have done anything different in this case? Dr. Chijioke Nze: No. I think in this particular case, I do think the fact that she did have a good response for a long duration of time, and did seem to have chemosensitive disease, I would probably still have tried a salvage therapy and autologous transplant in this patient. In the event that she was refractory, or had early relapse, and in that case, I would consider her to not be chemosensitive and would definitely have sought some more active therapies such as CAR T cell therapy through available products. Dr. Loretta Nastoupil: And then one last question for you: What if we just changed her age and we made her 79, but no other significant comorbidities, how would that have impacted your approach? Dr. Chijioke Nze: I'm going to turn that one over to you, I'm not exactly sure how I would treat with older patient with the same disease. Dr. Loretta Nastoupil: That's fair. So, if you have an older patient who has a late relapse, but not necessarily someone you would consider appropriate for salvage chemotherapy and high-dose therapy, then I think tafasitamab and lenalidomide would be probably my first choice in that setting, just based off of the L-MIND study. Dr. Chijioke Nze: Thank you, Dr. Nastoupil, for a great discussion of the management of diffuse large B-cell lymphoma. And thank you to all our listeners. We appreciate you tuning in to this episode of the ASCO Educational podcast.   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy, should not be construed as an ASCO endorsement.

Victorian Legacies
Episode 39: Valentina Gaio - Victorian (and Current) Attitudes to Slum/Working Class Diets

Victorian Legacies

Play Episode Listen Later Jan 15, 2023 55:57


In this episode I'm joined by Valentina Gaio. Like myself, Valentina's research interests are broad, from popular culture to crime and horror, and we initially discuss the contemporary 18th century media depiction of the French Revolution. Our main topic today, however, centres on Victorian views of food (specifically slum inhabitants' diets), and the similarities to contemporary 21st century food campaigns. Specifically, we focus on Valentina's study on Jamie Oliver's public campaign, and how Victorian/19th century attitudes towards poverty, disadvantaged communities, diet, and how to help marginalised people maybe have not changed as much as we might initially imagine About my guest: Valentina is a PhD student at Queen's University in Kingston, Ontario, who's currently preparing for her comprehensive exams. Her field of interest is Modern Popular Culture with a focus on crime and horror. She is interested in queer themes, social structures and hierarchies, and grief. She is currently working on an investigation of contemporary English reporting of the French Revolution. In addition to her academic work, she is an editor of the literary journal The Lamp and a prose writer. She received her BA in Modern Foreign Cultures and Languages at the University of Parma, her MA in English Studies at the University of Venice, and her MFA in Creative Writing from the University of St Andrews in Scotland For more information on Valentina's work, check out the details below:Instagram: @popcompromphttps://queensges.wordpress.com/reps/"Let Them Eat Nuggets": https://20vg41.wixsite.com/thedoldrums/post/let-them-eat-nuggets Check out Valentina's suggestions: (lInks to these can all be found in Valentina's article above)Love and Toil: Motherhood in Outcast London by Ellen Rosson"Food and the Cooking of the Working Class about 1900" by Eunice Schofield"The provision of school meals since 1906: progress or a recipe for disaster?" by Alan Finch"Jamie Oliver's War on Nuggets" by Dan Olson Sunless Skies, a Lovecraftian videogame with a Neo-Victorian setting.Valentina is helping to organise the Queen's Graduate Conference in Literature, so here is the live CFP: https://queensges.wordpress.com/queens-graduate-conference-in-literature-2/ Episode Credits: Episode Writer, Editor and Producer: Emma Catan Music: Burning Steaks (by Stationary Sign) - obtained via EpidemicSound Check us out at the following social media pages and websites! Facebook: https://www.facebook.com/victorianlegaciespodcastTwitter: @victorianlegac1Instagram: @victorianlegaciespodcastWebsite: https://emmacatan.wordpress.com/victorian-legacies-podcast/Email: victorianlegacies@gmail.com

The Alan Cox Show
Ghost Bag Returns/ Homemade Sucks/ Bitty Bum Wrestling/ Parma Porch Pirates/ More Bad Sex Songs/ Wilhelmina Cheerleader/ Aggro Auctioneer/ Black Funerals/ Jellyfish The Juggalette/ Call Screening/ Crying For Rambo/ Poundcake's Mom Calls/ Possible Bro

The Alan Cox Show

Play Episode Listen Later Jan 14, 2023 169:49


HORECA AUDIO NEWS - Le pillole quotidiane
4753 - Pomì rinnova logo e pack

HORECA AUDIO NEWS - Le pillole quotidiane

Play Episode Listen Later Jan 11, 2023 2:21


Pomì, il brand di polpe e passate di pomodoro 100% italiano, si presenta a inizio 2023 con un rebranding completo a sigillo dei suoi 40 anni che comprende un nuovo logo, un nuovo packaging e un rinnovato design system partendo dal mercato Italia.Nato agli inizi degli anni '80 in provincia di Parma, nel cuore della food valley italiana, Pomì si è contraddistinto fin da subito per la sua capacità innovativa con un pack in cartone, unico per la tipologia di prodotto, che lo ha portato sulle tavole di tutto il mondo.

OCW Sport
Tutti i Social contro Inzaghi: "rivogliamo Conte".. Buffon una Leggenda!

OCW Sport

Play Episode Listen Later Jan 11, 2023 91:49


Tutti Convocati
Inter, ci pensa Acerbi

Tutti Convocati

Play Episode Listen Later Jan 11, 2023


Un ottavo di fatica in Coppa Italia per l'Inter a San Siro, contro il Parma del vecchio (ma sempre buono) Buffon: prima si ritrova in svantaggio 1-0 col gol di Juric, poi agguanta il pari con Lautaro. Templi supplementari, tempi maturi per un altro uomo maturo, quindi tempi Acerbi che infila il 2-1 definitivo con un colpo di testa quasi da fuori area. E nel frattempo a Milano tramonta ancora l'idea stadio. Ne parliamo col tifoso nerazzurro Beppe Severgnini. La Milano del calcio (almeno da una parte) può sorridere, quella del basket un po' meno, perché arriva l'ennesima sconfitta in Eurolega per Milano. E alla Virtus non va meglio... il punto sulla serataccia delle italiane della palla a spicchi con Andrea Tosi della Gazzetta. C'eravamo tanto amati... Ancelotti e Gattuso si affrontano con Real e Valencia in Supercoppa di Spagna e le dichiarazioni della vigilia lasciano trasparire vecchie ruggini non eliminate dopo l'avvicendamento sulla panchina del Napoli. Intanto, in Francia impazza la bufera sul Presidente Federale Le Graet, sospeso dopo le accuse di molestie sessuali e alcune infelici uscite su Zidane e Benzema. Pagina bollente di esteri con Filippo Maria Ricci da Madrid e Danilo Ceccarelli da Parigi.

Vacation Mavens
214 Northern Italy + Big Announcement

Vacation Mavens

Play Episode Listen Later Jan 10, 2023 52:10 Very Popular


Happy New Year! We are back and apologize for taking so long to release a new episode. Moving forward, we will strive to have one episode a month to share our travels and tips, as we continue to each put more time into our respective websites. But first, Tamara has a big announcement and that is that she is hosting a women-only small group trip to Iceland in September 2023! You can get all the information on YourTimetoFly.com and she really hopes that some listeners will be able to join! Note that there is a discount of 15,000 ISK if you register by January 15, 2023. Next Tamara tells us all about her two-week trip to Northern Italy! Some highlights include: 5 Days in Piedmont full of wine tasting, truffle hunting, and great food Her stay at La Villa Hotel in Piedmont A wine tour with Piedmont Food and Wine Tours Grand Hotel Tremezzo in Lake Como 2 days in Milan (highlights walking tour with LivTours) Hired DayTrips to visit Bergamo, Brescia, Sirmione on Lake Garda, and Borgo sul Mincio 2 days in Verona (mentioned Love in the Villa and Letters to Juliet movies), ½ day walking tour with LivTours 2 days in Bologna Cooking class in Bologna with Cesarine 2 days in Parma Day trip with Food Valley Travel Return to Milan

'Código Puskas' By Editorial Puskas
347 - Actividad de Copas y Manchester United pasa por encima del Charlton Athletic, mientras que el Inter vence en tiempo extra al Parma

'Código Puskas' By Editorial Puskas

Play Episode Listen Later Jan 10, 2023 51:12


- Se juegan los cuartos de final de la Copa de la Liga Inglesa. Manchester United y Charlton Athletic se disputan un boleto para las semifinales, mientras que Newcastle y Leicester City juegan por el otro. - En la Coppa Italia, Inter y Parma en los octavos de final de la justa. - Chelsea logró acuerdo con el Atlético de Madrid por el préstamo de Joao Félix.

Bears Beyond The Gate
Ep130 - Abject display at London Irish and our next European challenge

Bears Beyond The Gate

Play Episode Listen Later Jan 9, 2023 51:55


In this week's show the boys discuss the hugely dissapointing display that led to the 23-7 loss away at London Irish. Too many penalties, turnovers and mistakes and too little possession and territory was the story of a wet and miserable day in West London for Bears' fans.We analyse the performance and ask what next for Pat and the team after yet another league defeat.We also look ahead to the European Challenge Cup fixture in Parma against Zebre. We discuss the likely team and assess how important a cup run is to Bristol's faltering season.All this and more with Tony, Miles, Pete and Lee.

Lega Football
Episode 33: The Hakan Sükür Interview: The Career of a Living Legend

Lega Football

Play Episode Listen Later Jan 3, 2023 73:49


Hakan Sükür is a former Inter Milan, Galatasaray, Parma, Torino, Blackburn Rovers and Turkey striker who scored just under 400 goals for club and country.Sükür joins David for his first English-spoken interview:- THAT RECORD! Turkey vs South Korea 2002, FIFA World Cup Fastest Goal in history.- Where Sükür is based now, why, and what he is doing there.- Sükür's thoughts on Turkey's and Italy's absences from FIFA 22- Insight into Sükür's first experience with Italian football and Marcello Lippi.- Marcello Lippi insisted on Sükür signing for Inter Milan- Sükür's stunning success at Galatasaray in the early 90s- Insight into how Sükür spearheaded Gala's historic elimination of Eric Cantona's Manchester United team from the UEFA Champions League.- Galatasaray's first UCL Group Stage victory over Romario's Barcelona.- Sükür is a second-generation Turkish immigrant. Find out where his ancestry hails from.- Sükür talks about his history with Christian Vieri- Sükür's best goals in UEFA Europa and Champions League- Hakan talks about a potential upcoming documentary series- That star-studded Inter Milan team of 2001- THAT volley in the Derby della Madonnina, the Inter-Milan derby- Sükür's move to Parma with Arrigo Sacchi- Hakan won the Coppa Italia with Cannavaro, Taffarel, Di Vaio at Parma- Sükür's experience in the English Premier League with Blackburn Rovers- Hakan discloses his Best Coach and Best Goal- Sükür discusses his best and most important goals- His Club Silverware and International Career- Sükür's Individual Achievements - The Hakan Sükür Wikipedia Page- That TRT Commentator sacked on the spot for talking about Sükür- Hakan Remembers Siniša Mihajlović- A Character Reference from Hakan's TranslatorYou can watch the interview on YouTube: https://youtu.be/vrPsjpnfxe8Wikipedia: https://en.wikipedia.org/wiki/Hakan_SükürYouTube  @HakanSukur9  Twitter @HakanSukur  Instagram hakansukur9https://www.facebook.com/hakansukurTwitter @DavidFerrini_Instagram @DavidFerrini_Listen to our podcasts:https://open.spotify.com/show/1ese2PN...LegaFootball pods are also available on Apple, Google, Amazon, iHeartRadio, Player FM and more!Lega Football focuses on many aspects of Calcio, not just Serie A and the national team, but also the lower Leagues. Twitter @legafootballWeb www.legafootball.comPodomatic, Apple Music, Google Podcasts, Amazon, Spotify and more.We aim to be a fresh, vibrant approach to the beautiful Italian game from knowledgeable voices in Calcio.

Indagini
Parma, 4 agosto 1989 - Seconda Parte

Indagini

Play Episode Listen Later Jan 1, 2023 44:55


Un camper, marca Ford, con sei posti letto, bianco con strisce beige. Partì da Parma il 4 agosto 1989, destinazione Spagna, o forse Nordafrica. Comunque, vacanze. Era di proprietà di una famiglia composta da quattro persone: la famiglia Carretta.A inizio settembre quel camper non era ancora tornato. Giuseppe Carretta avrebbe dovuto riprendere il lavoro nell'azienda di cui era il contabile ma non si era fatto vivo, nemmeno una telefonata. Eppure, dissero i suoi colleghi, avvertiva anche se tardava pochi minuti. Con lui era sparita la moglie, Marta Chezzi. Neppure dei due figli, Nicola e Ferdinando, si sapeva più nulla.Iniziò la caccia al camper: per settimane arrivarono segnalazioni da tutta Italia, ma anche dall'estero. Alla fine venne ritrovato, parcheggiato in una strada di Milano. Degli occupanti non c'era nessuna traccia.Iniziò a diffondersi la voce che Giuseppe Carretta fosse scappato portando con sé 10 miliardi di lire sottratti alla sua azienda: fondi neri, e quindi non denunciati. Si disse che l'intera famiglia si fosse trasferita ai Caraibi a godersi i soldi. Che fossero tutti lontani e felici.Per quasi dieci anni i Carretta vennero segnalati in varie parti del mondo. Investigatori e giornalisti partivano alla ricerca ma ogni pista alla fine si rivelava falsa, o inconsistente.Fino a che un poliziotto inglese fermò un ragazzo che in moto, a Londra, stava facendo zig zag tra le auto…

Indagini
Parma, 4 agosto 1989 - Prima Parte

Indagini

Play Episode Listen Later Jan 1, 2023 37:21


Un camper, marca Ford, con sei posti letto, bianco con strisce beige. Partì da Parma il 4 agosto 1989, destinazione Spagna, o forse Nordafrica. Comunque, vacanze. Era di proprietà di una famiglia composta da quattro persone: la famiglia Carretta.A inizio settembre quel camper non era ancora tornato. Giuseppe Carretta avrebbe dovuto riprendere il lavoro nell'azienda di cui era il contabile ma non si era fatto vivo, nemmeno una telefonata. Eppure, dissero i suoi colleghi, avvertiva anche se tardava pochi minuti. Con lui era sparita la moglie, Marta Chezzi. Neppure dei due figli, Nicola e Ferdinando, si sapeva più nulla.Iniziò la caccia al camper: per settimane arrivarono segnalazioni da tutta Italia, ma anche dall'estero. Alla fine venne ritrovato, parcheggiato in una strada di Milano. Degli occupanti non c'era nessuna traccia.Iniziò a diffondersi la voce che Giuseppe Carretta fosse scappato portando con sé 10 miliardi di lire sottratti alla sua azienda: fondi neri, e quindi non denunciati. Si disse che l'intera famiglia si fosse trasferita ai Caraibi a godersi i soldi. Che fossero tutti lontani e felici.Per quasi dieci anni i Carretta vennero segnalati in varie parti del mondo. Investigatori e giornalisti partivano alla ricerca ma ogni pista alla fine si rivelava falsa, o inconsistente.Fino a che un poliziotto inglese fermò un ragazzo che in moto, a Londra, stava facendo zig zag tra le auto…

Acquired Tastings
Wines to drink for New Year's Eve

Acquired Tastings

Play Episode Listen Later Dec 29, 2022 67:46


Dad and Josh are joined by Anne Marie for New Year's Eve wines. Josh's Champagne was Pierre Gimonnet Blanc de Blanc.  Josh brings popcorn with two different sauces. One sauce was a Sichuan Chili crisp and the other was Zhong sauce.  Both were made by Fly By Jing.  He also brings Duckham, and Porchetta di Parma. Dad brings the J. Lassalle Premier Cru Champaign.  His sides were planned to match a New Year's Eve or Christmas meal.  He brings Prime Rib, steamed Broccoli and a simple baked potato.  Marie brings Chandon Brut sparkling wine.  For her sides she brings an amazing cheese, garlic bread,  cheese mushroom caps and Ferrero Rocher chocolate cups.  She tells about her special connection with Chandon wines on three continents.  They have a great time sipping and snacking! Dad again gets all "heated up" and has to figure out how to put the fire out.

Heidi and Toni Explore Cleveland
Little Birdie Wine Nest

Heidi and Toni Explore Cleveland

Play Episode Listen Later Dec 26, 2022 47:10


The Little Birdie Wine Nest is located at 6060 Broadview Road, Parma, OH 44134. This venue combines coffee and wine, happy hour, and grazing boards, a creative crafting corner and yoga! You can find more information about their ticketed special events and yoga classes at their website https://www.littlebirdiewinenest.com, and you can follow them on Facebook and Instagram. We also feature information about the Cleveland Cookie Dough Company in this episode. You can find out more information on them and where to find their edible cookie dough at https://www.clecookiedough.com, they are also on Facebook, Twitter and Instagram. Heidi and Toni Explore Cleveland is produced by Heidi Johnson and Toni Gambino; all rights reserved. Please follow us on Facebook, Instagram, Snapchat, Twitter and TikTok. https://exploringclevelandwithheidiandtoni.com. Email: exploringclevelandht@gmail.com The views and opinions expressed in this podcast belong to the content creators and not the business, organization, affiliates, or their employees. This podcast is for entertainment purposes only. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/heidi-johnson39/support

J-TACTICS's show
J-World S04 E14

J-TACTICS's show

Play Episode Listen Later Dec 23, 2022 20:51


Quattordicesima puntata della quarta stagione della rubrica, nel canale spreaker J-TACTICS, dedicata alle women ed alle giovanili della Juventus, J-WORLD.Tre punti sotto la neve e avventura Champions più viva che mai per le Juventus Women, che battono lo Zurigo grazie a una prova di qualità e al termine di una partita mai in bilico, impreziosita dal fantastico poker di Cristiana Girelli.5-0 senza storie per le nostre ragazze ai danni delle svizzere dello Zurigo.Imbattute contro le campionesse in carica, ma fuori dalla Champions.La Juve ci prova, ma non basta: lo 0-0 a Lione condanna le bianconere a salutare la competizione.Il girone di andata dei bianconeri della next gen. si chiude con una sconfitta per 0-3 contro la Virtus Verona.Questa è soltanto la seconda sconfitta tra le mura amiche per i bianconeri, dopo quella rimediata a inizio stagione contro il Padova.Decisive le reti di Juanito Gomez, sul finale di primo tempo, e quelle di Talarico e Zarpellon nella ripresa, quest'ultima arrivata a gara praticamente conclusa.Continua l'ottimo momento della formazione veneta, la più in forma del campionato già prima di questa sfida, con la quinta vittoria nelle ultime sei partite.Da segnalare la prima convocazione in Next Gen per Hasa e Yildiz.Per quest'ultimo è arrivata anche la prima presenza tra i professionisti, essendo subentrato a gara in corso.La Juventus Next Gen viene beffata nel finale.Al "Briamasco" passa 2-1 il Trento in pieno recupero grazie alla splendida punizione di Pasquato. Quello dell'ex bianconero non è stato l'unico bel gol di giornata, però: sempre parlando di calci piazzati, la punizione di Iocolano che aveva riequilibrato le sorti del match è stata un'altra grande giocata di questo match.Ad aprire le marcature per i trentini ci aveva pensato Damian, nel primo tempo.I bianconeri chiudono, così, il 2022 senza punti, ma sicuramente con l'obiettivo di ripartire più forte nel nuovo anno.Si chiude con una vittoria per 1-0 nello scontro diretto contro il Parma, a Vinovo, il 2022 dell'Under17 allenata da Mister Panzanaro.Decisiva la rete di Boufandar in pieno recupero, nel secondo tempo.Un gol praticamente allo scadere per sbloccare una partita che stava viaggiando sulle ali dell'equilibrio, soprattutto dal punto di vista del risultato.Un gol che regala un successo importante nel match contro gli emiliani valevole per la prima giornata del girone di ritorno del campionato di categoria.Con questi tre punti i bianconeri salgono al primo posto in classifica in solitaria a quota 30 punti dopo 13 giornate disputate, staccando proprio il Parma e il Bologna entrambe ferme a 27 punti in graduatoria.Anche quest'anno sarà nostra guida nel mondo Juve, il sempre competente e preciso amico Roberto Loforte, Fuori rosa TV.

pharmaphorum Podcast
Focusing on the evolution of biotechnology and R&D

pharmaphorum Podcast

Play Episode Listen Later Dec 22, 2022 13:19


Following an invite to fly into Parma, Italy to witness first-hand the press launch of the considerable structure that is the Chiesi Group's new €85 million Biotech Centre of Excellence, pharmaphorum web editor Nicole Raleigh spoke with Chiesi's head of global manufacturing, Antonio Magnelli.

Moon Safari
S9P8 - Techno Made in Berlin e le poesie di Hermann Hesse

Moon Safari

Play Episode Listen Later Dec 20, 2022 12:23


Moon Safari, esplorazioni musicali e poetiche al chiaro di lunaDi e con Claudio PetronellaIn onda su RBE Radio TV e su Radio CapodistriaStagione 9 - Puntata 8La selezione musicale "made in Berlin" di Moon Safari incontra le poesie di Hermann Hesse.www.rbe.it/trasmissioni/moon-safari- PLAYLIST MUSICALELink Spotify > https://open.spotify.com/playlist/5lLfxVYnmeNL2yni6pjQ4t?si=iQnPKnu-SJWUBCz_vTbgjAPaul Kalkbrenner - AzureJan Blomqvist, The Bianca Story - Dancing People Are Never WrongModerat - Rusty NailsJon Hopkins, Moderat - Abadon Window - Moderat remixApparat - HeroistJan Blomqvist - Black Hole NightsTale Of Us - North StarPaul Kalkbrenner - Altes KamuffelDardust - Un nuovo inizio a Neukolln- PLAYLIST POETICAHermann Hesse - Canzone d'amorePer dire cos'hai fatto di me, non ho parole.Cerco solo la notte, fuggo davanti al sole.La notte mi par d'oro più di ogni sole al mondo,sogno allora una bella donna dal capo biondo.Sogno le dolci cose, che il tuo sguardo annunciava,remoto paradiso di canti risuonava.Guarda a lungo la notte e una nube veloceper dire cos'hai fatto di me, non ho la voce.Hermann Hesse - Senza di teIl mio cuscino mi guarda di nottecon durezza come una pietra tombale;non avevo mai immaginato che tanto amaro fosseessere soloe non essere adagiato nei tuoi capelli.Giaccio da solo nella casa silenziosa,la lampada è spenta,e stendo pian piano le mie maniper afferrare le tue,e lentamente spingo la mia fervente boccaverso di te e bacio me fino a stancarmi e ferirmi —e all'improvviso son sveglio,ed intorno a me la fredda notte tace,luccica nella finestra una limpida stella —o tu, dove sono i tuoi capelli biondi,dov'è la tua dolce bocca?Ora bevo in ogni piacere la sofferenzae veleno in ogni vino;mai avrei immaginato che fosse tanto amaroessere soloessere solo e senza di te!Hermann Hesse da "Poesie d'amore" (Mondadori, Milano, 2011)Traduzione di A. RuchatHermann Hesse - EleonoraLe sere d'autunno mi ricordano te.Giacciono oscuri i boschi, il giorno muorea piè dei colli in rosse gloriole.In un villaggio vicino piange un bimbo.A passi lenti se ne va pel boscoa radunar le ultime foglie il vento.Poi sale, da tempo abituata al cupo sguardo,solitaria la falce della lunaalta nel cielo con la mezza luceemergendo da terre sconosciute.Percorre indifferente il suo sentierocingendo bosco, stagno, canne e viottolodi smorti, malinconici bagliori.Anche d'inverno quando le notti sono oscuree vorticano ai vetri come in giuocovento e fiocchi di neve ho spesso l'impressione di vederti.Risuona il piano, con sorriso insinuantemi parla al cuore il tuo profondo, cupocontralto, tu la più cruda delle donne care.Talvolta la mia mano va alla lampadae sulla vastità della parete si posa dolcemente la sua luce.Cupa dalla vecchia cornice occhieggia la tua immaginee mi ravvisa e sorride stranamente.Ma io le mani ti bacio ed i capellie ripeto il tuo nome sussurrando.Hermann Hesse da “Hermann Hesse, Poesie” (Guanda, Parma, 1978)

10,000 Pitches
Equal Time: Interview w/Parma Calcio's Annie Williams

10,000 Pitches

Play Episode Listen Later Dec 20, 2022 60:57


Equal Time Soccer's Matt Privratsky chats with Annie Williams of Parma Calcio! #SerieAFemininoPresented by Pentz Homes.

The Bourbon Life
Season 3, Episode 50: Steve Coomes, Author & Speaker - Pairing Country Ham with Bourbon

The Bourbon Life

Play Episode Listen Later Dec 16, 2022 93:36


In this Episode of The Bourbon Life Podcast, Matt and Mark spend some time hanging out live in The Bourbon Life Studios with author and speaker, Steve Coomes, talking all about Country Ham and Bourbon. The guys talk with Steve about his background in the restaurant industry and journalism and how that led him to the worlds of Country Ham and Bourbon, the incredible Country Hams that are being crafted in the US today that are on par with the world-famous Prosciutto di Parma and Jamon Iberico, and how to properly pair Bourbon, or Rye, with Country Ham as well as with other foods. They also taste and review the recently released William Heavenhill 15-Year Bourbon, the also recently released Nelson Bros. 15-Year Rye, and a Booker's 2019-004 “Beaten Biscuits” Batch. And they pair these high proof whiskies with a 24-month aged Broadbent's Country Ham and a 30-month aged Newsom's Country Ham. Learn more about Steve at:  www.stevecoomes.com For more information on these delicious Country Hams visit: www.broadbenthams.com www.newsomscountryham.com This Episode of The Bourbon Life Podcast is sponsored by Liquor Barn, The Stave Restaurant, Three Chord Bourbon, and Spirits of French Lick. Check out all of our amazing sponsors online at:  www.liquorbarn.com     www.thestavekentucky.com  www.threechordbourbon.com www.spiritsoffrenchlick.com

The Alan Cox Show
Gwen Sits In/ Wiener News/ Mindless Content/ Texas Tacklers/ Parma Chameleon/ Perez Billton/ Steve Byrne/ Dick Talk/ Yacht Doc

The Alan Cox Show

Play Episode Listen Later Dec 13, 2022 160:57


3News Now with Stephanie Haney
Video Shows Stolen Car Crash Into Parma Home, Family Fights To Stop Parole Of Their Mom's Murderer

3News Now with Stephanie Haney

Play Episode Listen Later Dec 13, 2022 8:19


Tuesday, December 13, 2022: Find out what we know about a teen who stole a car and crashed it into a house in Parma where a mother and her baby were inside, a family calling for help to keep the murderer of their mother from getting paroled, the controversial Title IX resolution passed by the Ohio Board of Education that is against the interest of LGBTQ+ students on the same day that President Biden signs same-sex marriage protection into law, and more on 3News Daily with Stephanie Haney. Connect with Stephanie Haney here: http://twitter.com/_StephanieHaney http://instagram.com/_StephanieHaney http://facebook.com/thestephaniehaney Read more here: Photos: Car slams into Cleveland home following stolen car pursuit https://www.wkyc.com/article/news/local/cleveland/car-slams-into-cleveland-home-pictures/95-1198fbd5-86a0-499b-a32a-fafe1437c292 Family fights to keep mom's killer behind bars as Ohio Parole Board considers release of Thomas Yanasak: Petition launched to keep him incarcerated https://www.wkyc.com/article/news/crime/carol-smith-murder-medina-thomas-yanasak-ohio-parole-board-possible-release/95-26440b30-29bc-4cce-854d-2d5bdd72c0cc State panel recommends year suspension for Cuyahoga County Judge Daniel Gaul due to misconduct https://www.wkyc.com/article/news/local/cuyahoga-county/state-panel-recommends-year-suspension-cuyahoga-county-judge-daniel-gaul-misconduct/95-e217cf8d-8444-4c41-a8cf-c7b900489794

Equal Time Soccer
Episode 96: Annie Williams

Equal Time Soccer

Play Episode Listen Later Dec 11, 2022 60:56


Annie Williams has played professional soccer all over the world - Costa Rica, Iceland, Sweden, and now Italy. Matt sits down with her to talk about her role at Parma (2 min), how her game as translated across leagues (6 min), adjusting to each new league (10min), what other MN pros she connects most with (15 min), playing for a club with an American owner who invests in women's soccer (22 min), American/Italian questions and quirks (29 min), day to day life of a pro (43 min), hosting friends and family (52 min), and a Country Quiz about all the places she's played pro! Presented by Pentz Homes.

Salvatore racconta
092 - Parma. Tra duchi, imperatrici, prosciutto e parmigiano.

Salvatore racconta

Play Episode Listen Later Dec 10, 2022 16:03


Alla scoperta di Parma. Città del prosciutto e del parmigiano, ma anche dell'opera e dell'arte.Oltre che la città più francese di tutta Italia.Vuoi ricevere la trascrizione dell'episodio? http://eepurl.com/hVUHW5Trovi tutto l'archivio e anche molti altri materiali sul sito. www.salvatore.com/salvatoreraccontaPer accedere agli episodi premium, vai su www.patreon.com/salvatoreraccontaTesto e voce di Salvatore GrecoSullo sfondo:Bright eyed blues – Unicorn heads – Licenza Creative Commons CC 0Chocolate cookie jam – An Jone - Licenza Creative Commons CC BY 4.0Everything where it needs to be – Nat Keefe & Hot buttered rum – Licenza Creative Commons CC BY 4.0

MELOG Il piacere del dubbio

Molti ricorderanno la drammatica vicenda dei due fratellini, scomparsi nel 2006 e ritrovati morti due anni dopo, in fondo a una cisterna abbandonata, nel centro di Gravina, in Puglia. Ne ripercorriamo la storia con il giornalista Mauro Valentini e Luciano Garofano, già comandante dei RIS di Parma e consulente tecnico per l'Autorità Giudiziaria e gli studi legali, autori di un libro che finalmente prova a fare chiarezza sui tanti misteri del caso.

Mountain Murders Podcast
The School Teacher Murders and Ashland Tragedy

Mountain Murders Podcast

Play Episode Listen Later Dec 7, 2022 107:56


This week Mountain Murders brings you two episodes in one as a way of saying thank you for being an incredible supporter of our show!We kick off with a true crime case out of Parma, Ohio involving two school teachers were brutally murdered. Our second case covers a wild story in Ashland, Kentucky during the 1880s. Intro Music by Joe Buck YourselfHosts Heather and Dylanemail mountainmurderspodcast@gmail.comTo support the show join us at www.patreon.com/mountainmurderspodcast

Warriors Weekly
The Squadcast | Stafford McDowall | S1 E10

Warriors Weekly

Play Episode Listen Later Dec 7, 2022 18:56


Fresh off his try-scoring display in Parma, Stafford McDowall joins Craig and Murphy for the latest episode of The Squadcast, as the big centre tackles everything from Instagram influencers to team nights out.Listen now! Hosted on Acast. See acast.com/privacy for more information.

3News Now with Stephanie Haney
Reward Issued For Man Wanted For Killing 4 Year Old Boy, Akron Student Gets Loaded Gun Past Security

3News Now with Stephanie Haney

Play Episode Listen Later Dec 6, 2022 6:44


Tuesday, December 6, 2022: Learn the reward available for helping find a man wanted for killing a 4 year old boy in Mahoning County, how high bond was set for the man accused of killing a Youngstown man and wrapping him in plastic, how Ohio lawmakers want to get tougher on people who kill first responders, the next steps for the Cleveland Community Police Commission, and more on 3News Daily with Stephanie Haney. Connect with Stephanie Haney here: http://twitter.com/_StephanieHaney http://instagram.com/_StephanieHaney http://facebook.com/thestephaniehaney Read more here: $1 million bond continued for Parma man charged with murder after missing man's body found wrapped in plastic https://www.wkyc.com/article/news/crime/paul-addicott-parma-murder-suspect-body-wrapped-plastic-missing-man-ryan-krebs/95-39790145-ea2d-4f72-ad7f-10fbcc49c3e1 US Marshals now offering $10,000 reward for information on fugitive accused of killing Mahoning County 4-year https://www.wkyc.com/article/news/crime/us-marshals-10000-reward-fugitive-accused-killing-mahoning-county-4-year-old/95-18c9e3c8-1709-4f52-8fe0-8bdb01fd8ddb After death of Cleveland firefighter Johnny Tetrick, Ohio General Assembly considering stricter vehicular homicide law https://www.wkyc.com/article/news/local/cleveland/after-death-cleveland-firefigher-johnny-tetrick-ohio-general-assembly-considering-stricter-vehicular-manslaughter-law/95-086dec73-7c34-49fe-aac0-5fbd36c93fe1 Ohio announces demolition plans for 2,277 buildings in 42 counties: See the full list of impacted addresses https://www.wkyc.com/article/news/local/ohio/demolition-plans-ohio-buildings-governor-mike-dewine/95-9485e68e-ba9d-4893-9679-43c28a15080b State of Ohio to demolish 825 dilapidated buildings, including more than 400 in Cuyahoga County https://www.wkyc.com/article/news/local/ohio/state-of-ohio-demolish-825-dilapidated-buildings-more-than-400-cuyahoga-county/95-b59804ef-180d-46c5-ad13-a256be3c6f7f City of Cleveland announces parade for Glenville High School football team following state championship https://www.wkyc.com/article/news/local/cleveland/cleveland-announces-parade-f-glenville-high-school-football-team-following-state-championship/95-5616aead-7ae3-46a1-8103-5273b533a694 25 places to hide your Elf on the Shelf this holiday season https://www.wkyc.com/article/news/nation-world/25-places-to-hide-your-elf-on-the-shelf-this-holiday-season/507-496539693

Mycotoxin Matters
#23 The Mycotoxin-related Health Impact of Shifting to Plant-based Diets | Prof. Chiara Dall'Asta

Mycotoxin Matters

Play Episode Listen Later Dec 6, 2022 22:02


In recent years, with a look to creating a healthier and more sustainable diet, plant-based alternatives such as dairy and meat substitutes have been developed in order to reduce the consumption of animal-based foods. As these plant-based alternatives continue to develop and expand within the market, the question arises: 'what do we know about the mycotoxin-related health impacts of shifting to a plant-based diet?'  We are joined by Professor Chiara Dall'Asta to discuss a study that was recently published in the Journal of Exposure and Health, which assessed this topic. Professor Dall'Asta is currently an associate professor of food chemistry at the Department of Food Science at the University of Parma in Italy and is a well-known and highly respected researcher in the area of mycotoxins. In addition to her research activities, she is also an expert member of several working groups of the European Food Safety Authority.  

True Crime BnB
Episode 46; 1921 Parma OH Teacher Murders & 2016 Columbus Restaurant Machete Attack

True Crime BnB

Play Episode Listen Later Dec 2, 2022 51:48


Not gonna lie, Crime Family, Episode 46 caught us a little bit by surprise. We both independently came up with 'hometown' stories and didn't plan it that way. So, we welcome you on our trips down memory lane, as we have seen too much heaviness in the news lately and just needed to turn down the heat on current events.For a record-setting third episode in a row, Beth is back as the bad guy. This week she covers a murder that took place in a suburb of Cleveland, Ohio in 1921. Parma Township, the predecessor to the City of Parma, was a rural farming community that had a tiny, one-room schoolhouse called the Parma Central School. In February, 1921, its two teachers were brutally bludgeoned to death on a rural road on the way to catch the streetcar home. Hear the details of the case, the theories, and the suspects. Also, we'll discuss the well-intentioned but mindless destruction of the crime scene by local searchers, which is likely why this haunting case remains unsolved 101 years later.Bailey also takes us back to her hometown in the northeast suburbs of Columbus, Ohio. In 2016, a beloved local restaurant was targeted in a terroristic machete attack that injured four people, several critically. The aftermath of this attack nearly wiped out the restaurant, but Bailey will fill you in on how the victims are doing six years later. She'll also tell how the Owner of the Nazareth Restaurant has fared through the years, and how his positive outlook is part of his local appeal.When you finish this episode, please go check out Deb and Beth (or Shelby) at Dying to be Found, whose trailer you hear at the beginning. We are podcaster buddies with Deb and we were honored to be invited to join her in her Episode 41 a couple of weeks ago. So please give Dying to be Found a listen, and subscribe so you won't miss any of their episodes.We are feeling a little bit nostalgic after this episode, so we are going to have a glass of wine in front of the fire, give our fluffy black cat extra treats, and you are, as always, welcome to join us. Thank you for stopping by, we're glad you're here!. . . . .If you enjoy our show, please rate and review on Apple Podcasts or GoodPods, or give us a 5-star rating on whatever platform you prefer!https://linktr.ee/TrueCrimeBnB?utm_source=linktree_profile_share<sid=9e8aa538-d3ee-4823-b2e1-cb1625692e7aYou can find us on Instagram, Twitter, or Facebook @TrueCrimeBnBYou can send us an email at TrueCrimeBnBPod@gmail.comAnd lastly, we would love and appreciate any amount of your support at Patreon, here:https://patreon.com/TrueCrimeBnB?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=creatorshare_creator

J-TACTICS's show
J-World S04 E11

J-TACTICS's show

Play Episode Listen Later Dec 2, 2022 35:28


Undicesima puntata della quarta stagione della rubrica, nel canale spreaker J-TACTICS, dedicata alle women ed alle giovanili della Juventus, J-WORLD.La Juve trova un buon pareggio all'Allianz Stadium contro un temibile Arsenal, e chiude la prima metà della fase a gironi seconda, proprio dietro le Gunners. 1-1, con reti tutte nella ripresa, nel giro di pochi minuti.La Juve non va oltre il pareggio 1-1 in casa contro il Como, ed è un pareggio che fa un po' male, perchè la Roma capolista ha battuto il Pomigliano e va a +6 in classifica sulle bianconere.La grande giornata firmata Next Gen all'Allianz Stadium si conclude con un pari spettacolo della squadra di Brambilla contro il Mantova, che prova due volte ad andare via ma fa i conti con uno Iocolano in stato di grazia.2-2 il risultato finale davanti ad oltre trentamila spettatori allo Stadium.A Salò, al "Lino Turina", passa la Feralpi con il punteggio di 2-1.Una vittoria, quella dei lombardi, che interrompe una striscia di otto risultati utili consecutivi da parte dei bianconeri.La Juventus Next Gen non perdeva da oltre un mese, tenendo in considerazione il campionato e la Coppa Italia.Vittoria di prestigio per i ragazzi allenati da Mister Panzanaro.A Vinovo il Derby della Mole Under17 è bianconero.Vittoria per 2-1 della Juventus con i gol di Finocchiaro e di Meringolo, quest'ultimo subentrato dalla panchina.Tre punti che valgono tanto anche per come sono arrivati: il Torino era riuscito a sbloccare l'incontro con Perciun, ma si è visto rimontare a fine primo tempo e superare in pieno recupero nella ripresa.Una vittoria che proietta i bianconeri al secondo posto in classifica, a 23 punti, a una sola lunghezza dal Genoa capolista.Pari e patta tra la nostra Under16 e quella del Parma: 0-0 e bianconeri che tornano dalla trasferta in Emilia-Romagna con un punto che muove la classifica e li porta a quota 12.Un buon risultato, tenendo anche in considerazione il fatto che sono riusciti a fermare la capolista Parma (al primo posto in classifica prima di questa giornata, a pari punti con Genoa e Torino).Esce senza punti dal "Quirino Zanichelli" di Parma l'Under15 di Mister Benesperi.Gli emiliani vincono 2-1 grazie alla doppietta di Muto che segna in sequenza nel giro di un minuto e lancia la sua squadra verso il successo finale.Accorcia le distanze al 20' Gecaj, ma non basta.I bianconeri rimangono a quota 14 punti dopo otto giornate di campionato.Successo di misura importantissimo per la Primavera femminile allenata da Coach Piccini che si impone 1-2 sul campo dell'Inter.Una vittoria che ha un valore enorme, anche e soprattutto perchè è arrivata in rimonta.Il primo tempo, infatti, si è chiuso 1-0 per le nerazzurre con la rete di Razza, ma nella ripresa Requirez prima e Dauria poi ribaltano il risultato e regalano tre punti d'oro alle bianconere che salgono, così, a quota 19 punti dopo otto giornate disputate.Vittoria ampia nel campionato regionale per l'under17 femminile di Mister Scrofani che a Garino supera le pari età del Cit Turin.A segno Boveri, Casella, Corda, Ferraresi, Gallina, Iannaccone, Mariotti, Perfetti, Robino e Xhumaqi.19-1 il risultato finale per le nostre ragazze.Grandissima vittoria per la formazione Under15 femm allenata allenata da Mister Vood che nella sua partita di campionato supera nettamente le pari età del Novara portando a segno più di dieci giocatrici.Vendemmia di gol 41-0 per le giovani bianconere.Non mancherà poi uno sguardo ai prossimi impegni delle women e delle giovanili:Inter-Juve women,Sabato 03 dicembre, ore 14:30.Next Gen-Sangiuliano City,Domenica 04 dicembre, ore 14:30.Fiorentina-Juce Under17,Domenica 04 dicembre, ore 11.Juve-Cremonese Under16,Domenica 04 dicembre, ore 15.Juve-Cremonese Under15,Domenica 04 dicembre, ore 13.Juve-Napoli Under19 femm.,Domenica 04 dicembre, ore 11.Torino-Juve Under17 femm.,Domenica 04 dicembre, ore11:30.ACF Biellese-Juce Under15 femm.,Sabato 03 dicembre, ore 15.Anche quest'anno sarà nostra guida nel mondo Juve, il sempre competente e preciso amico Roberto Loforte, Fuori rosa TV.

Untold Italy travel podcast
Dishes to try in Bologna and the Emilia Region

Untold Italy travel podcast

Play Episode Play 59 sec Highlight Listen Later Dec 2, 2022 59:10


Attention foodies! Among the goldmine that is Italian cuisine there is a shining jewel that is the region of Emilia-Romagna. You'll surely know its capital Bologna.Here they make Italian produce staples Parmigiano Reggiano, Prosciutto di Parma and Traditional Balsamic Vinegar of Modena. But, not content to make some of the finest foodstuffs in the land, they take it to the next level.Listen to our chat with Giulia Tamarri (star sign "tortellini) as we discover the delectable dishes you should try when you visit her beautiful region. Read the full episode show notes, including places mentioned here > untolditaly.com/152. Join us on tour in Bologna and Beyond - itinerary hereSupport the showOn tour - Trip schedule | Join us: Untold Italy Amici | Visit our online store | Follow: Instagram • Facebook • YouTube • Italy Travel Planning Community

The Break Room
You Could've Left The Door

The Break Room

Play Episode Listen Later Nov 30, 2022 11:33


It's hard to protect your things from thieves when THIS is the item that gets stolen.

SBS Italian - SBS in Italiano
Torta di erbe di Borgotaro: la ricetta di Serena Picelli

SBS Italian - SBS in Italiano

Play Episode Listen Later Nov 29, 2022 6:16


Oggi vi proponiamo un piatto tipico dei dintorni di Parma: la torta di erbe di Borgotaro. Si tratta di una ricetta gustosa e facile da preparare, con la particolare caratteristica di essere sempre diversa ad ogni preparazione.

Gift of the Day
E613 11.21.22 Toto, I don't think we're in Parma anymore...

Gift of the Day

Play Episode Listen Later Nov 26, 2022 14:29


What does David have to do to escape America? It just seems to keep following him relentlessly. On his way out of Italy, David stops in Parma as an unexpected side-trip making his way back to Milan to be closer to the airport. As the bells of the adjacent church rocked him out of bed the following morning, he couldn't believe his eyes. Was this Parma or Manhattan? Michelle offers a very serious homework assignment related to David's discovery that everyone should commit to. --- Send in a voice message: https://anchor.fm/red-kite-movement/message Support this podcast: https://anchor.fm/red-kite-movement/support

J-TACTICS's show
J-World S04 E10

J-TACTICS's show

Play Episode Listen Later Nov 25, 2022 26:36


Decima puntata della quarta stagione della rubrica, nel canale spreaker J-TACTICS, dedicata alle women ed alle giovanili della Juventus, J-WORLD.Crederci fino all'ultimo non è un'opzione.E' una missione, qualcosa che si vive partita dopo partita.Le Juventus Women ne danno una prova perfetta a Parma, ribaltando proprio nel recupero una gara che sembrava stregata, ed evitando una sconfitta pesante da digerire, in vista del grande appuntamento di Champions League che le attende in settimana.2-1 il risultato finale per le nostre ragazze.La Juventus Next Gen vince anche sul campo della Pro Patria e chiude un'altra super settimana dopo quella scorsa con i successi su Novara e Pro Vercelli.A Busto Arsizio i bianconeri si impongono 1-0 grazie al colpo di testa di Palumbo in avvio di ripresa, alla sua prima marcatura con questi colori.Un gol da tre punti, un gol che vale la terza vittoria consecutiva in campionato (per la prima volta nella storia dell'Under23, ore Next Gen) e che arriva dopo un altro 1-0, quello sul campo del Sangiuliano City che è valso l'accesso ai quarti di finale della Coppa Italia Serie C.La squadra di Mister Brambilla sale a quota 22 punti, al sesto posto in graduatoria.Tre punti importanti per l'under17 di Mister Panzanaro, ottenuti su un campo difficile come quello della Sampdoria.I bianconeri si impongono 0-2 in Liguria grazie ai gol di Biliboc e Pugno, segnati rispettivamente uno nel primo tempo e uno nella seconda frazione.Con questa vittoria i nostri ragazzi salgono a quota 20 punti, dopo nove gare giocate, e inanellano la terza vittoria consecutiva.L'Under16 allenata da Mister Rivalta chiude questo fine settimana con una sconfitta interna.Il Monza passa 1-3 a Vinovo, allo Juventus Training Center. Con questo risultato i bianconeri rimangono fermi a quota 11 punti in classifica e vengono raggiunti proprio dalla formazione biancorossa.Pari e patta tra l'Under15 allenata da Mister Benesperi e i pari età del Monza.Una sfida che si preannunciava combattuta, dal momento che le due squadre erano divise in classifica da un solo punto dopo le prime sei giornate (13 punti per i bianconeri, 12 punti per i lombardi).A Vinovo, allo Juventus Training Center, il match termina 2-2 con il doppio vantaggio della Juventus al termine della prima frazione grazie alle reti di Borasio e Bracco e con la conseguente rimonta dei biancorossi maturata nella ripresa con la doppietta di Borasio, subentrato dalla panchina.L'Under19 allenata da Coach Piccini, proprio come la Prima Squadra femminile, vince in rimonta contro le pari età del Sassuolo.3-2 per le bianconere al "Dino Marola" di Vinovo, al termine di un match davvero combattuto.Alle due reti di vantaggio neroverdi, firmate da Rufolo e Perselli rispettivamente al minuto 5 e al minuto 9 della prima frazione, hanno risposto Nava, Berveglieri (subentrata a gara in corso) e Moretti.Ed è proprio la rete di quest'ultima quella del sorpasso.Con questa vittoria le bianconere salgono a quota 16 punti in classifica, dopo sette giornate disputate.L'Under17 femminile di Mister Scrofani vince come al solito ampiamente contro il Freedom la sua partita di campionato, a livello regionale.Tante le giocatrici andate a segno: Bertora, Casella, Corda, Ferraresi, Gallina, Perfetti e Xhumaqi.19-0 il risultato finale per le nostre ragazze.Netto successo, in campionato, per l'Under15 femminile guidata da Mister Vood contro le pari età del Bulè Bellinzago.A segno per le bianconere Basciu, Bertoglio, Coppelli, Demarchi, Demuru e Piccardi.Altra valanga di gol, 13-0 per le giovani bianconere.Non mancherà poi uno sguardo ai prossimi impegni delle women e delle giovanili:Juve-Arsenal women,(Women Champions League)Giovedì 24 novembre, ore 21.Juve-Como women,Domenica 27 novembre, ore 14:30.Next Gen-Mantova,Domenica 27 novembre, ore 14:30.Juve-Torino Under17,Sabato 26 novembre, ore 15.Parma-Juve Under16,Sabato 26 novembre ore 16.Parma-Juve Under15,Sabato 26 novembre, ore 16:30.Inter-Juve Under19 femm.,Domenica 27 novembre, ore 14:30.Juve-Cit. Turin Under17 femm.,Domenica 27 novembre, ore 16:30.Juve-Novara Under15 femm.,Domenica 27 novembre, ore 17.Anche quest'anno sarà nostra guida nel mondo Juve, il sempre competente e preciso amico Roberto Loforte, Fuori rosa TV.

Haunted Attraction Network
Haunted Attraction Industry News for Nov 22nd

Haunted Attraction Network

Play Episode Listen Later Nov 23, 2022 11:21


Updated Holiday Haunts List; Funtown Splashtown USA & Sally Dark Rides unveil new Haunted Hotel Dark Ride at IAAPA; Creep It Real FESTIVE announces new celebrity guests and Fear Farm haunt experience; Brokepam Productions launches a Kickstarter campaign to fund their new haunt "The Haunting of Bloody Mary"; Jingle Hells returns to Awaken Haunted Attraction; Fear Columbus expands their Krampus: A Haunted Christmas Experience to two weekends; Zombie Joe's Underground Theatre Group presents "Turkeys! The Musical" and "Cabaret Macabre Christmas"; The Frida Cinema hosts a special screening and panel of Silent Night, Deadly Night; The Haunted Museum Nottingham is set to open in January of 2023; a Halloween-themed Thanksgiving display is featured on the local news in Parma, Ohio. Read more: https://mailchi.mp/hauntedattractionnetwork.com/haunt-news-haunted-hotel-comes-to-funtown-splashtown-usa

3News Now with Stephanie Haney
SUV Crashes In Apple Store In Massachusetts, Parma Murder Victim Found Wrapped In Plastic IDed

3News Now with Stephanie Haney

Play Episode Listen Later Nov 21, 2022 8:05


Monday, November 21, 2022: Find out what know about an SUV crashing into an Apple store and killing 1 person and injuring 16 others in Massachusetts. Plus, learn the jail time for Andrew Walls who was caught on video using a racial slur and punching a woman in Kent, the prison sentence for a Stark County mom who faked her daughter's terminal illness, new details about a murder victim found wrapped in plastic in Parma, and more on 3News Daily with Stephanie Haney. Connect with Stephanie Haney here: http://twitter.com/_StephanieHaney http://instagram.com/_StephanieHaney http://facebook.com/thestephaniehaney Read more here: 1 dead, 16 hurt after SUV crashes into Apple store in Massachusetts https://www.wkyc.com/article/news/nation-world/apple-store-suv-crash-massachusetts/507-02fb25f0-607d-4400-a7ca-b8a6ec2ce744 Kent man accused of attacking woman while using racial slur in Akron sentenced to 180 days in jail https://www.wkyc.com/article/news/local/akron/andrew-walls-akron-alleged-racial-slur-attack-highland-square/95-f8c65f9d-9ecd-4fc9-a3ba-a92f6a83a177 Stark County mother accused of faking daughter's life-threatening illness sentenced to prison https://www.wkyc.com/article/news/local/stark-county/stark-county-mother-accused-of-faking-daughters-terminal-illness-prison-sentence/95-e258cfe6-d7f9-43be-8608-e5689a849696 Victim identified in Parma homicide investigation https://www.wkyc.com/article/news/local/cuyahoga-county/victim-identified-parma-homicide-investigation/95-4c8c5a60-0b30-4ce8-8662-0943d3a60cae Parma man arrested after missing man's body found in basement https://www.wkyc.com/article/news/crime/parma-man-arrested-after-missing-body-found-basement/95-0fa65786-fbba-498a-9b20-2c7fe64bd834 Veteran Cleveland firefighter dies following hit-and-run on I-90; suspect arrested https://www.wkyc.com/article/news/local/cleveland/cleveland-fire-fighter-dies-after-being-struck-on-the-job-city-looking-for-suspect/95-4f39f068-307a-437c-9419-1d277ba8ebc0 $500,000 bond set for man arrested in alleged hit-and-run that killed Cleveland firefighter Johnny Tetrick https://www.wkyc.com/article/news/crime/suspect-leander-bissell-deadly-cleveland-crash-firefighter-johnny-tetrick/95-a9066200-b8de-4ea5-94b1-34bdde1020be Sheetz selling Unleaded 88 gas for $1.99 per gallon through November 28 https://www.wkyc.com/article/traffic/gas-prices/sheetz-unleaded-88-gas-199-gallon-sale-thanksgiving-2022/95-029d1a6c-f08f-454d-881e-52cc4e4d1d85

Learn Italian with Luisa
Ep. 98 - Giro turistico di Ravenna

Learn Italian with Luisa

Play Episode Listen Later Nov 19, 2022 27:08


Giro turistico di Ravenna - Spendieren Sie einen Cafè (1€)? Donate a coffee (1€)? https://ko-fi.com/italianoLivello A2/B1In questo episodio vi parlo di Ravenna e delle cose che si possono visitare in questa bella città Buongiorno cari amici e amanti dell'italiano e benvenuti al podcast numero 98.In questo episodio torniamo a parlare di turismo, visto che siamo tutti tornati da tempo al lavoro, vi faccio viaggiare con la fantasia e vi parlo di una città italiana che vale davvero la pena di visitare.Oggi parliamo di Ravenna.Ravenna si trova nella regione dell'Emilia Romagna. Questa regione è divisa in due regioni storiche ben distinte: l'Emilia che comprende le città di Ferrara, Piacenza, Parma, Modena e parte di Bologna e poi la Romagna dove ci sono le città di Forlì, Cesena, Rimini, Ravenna e l'altra parte di Bologna.Se andate a visitare Ravenna avete una grande scelta di cose da fare: è una città a 8 chilometri dal mare, quindi potete fare il bagno e rilassarvi sulla spiaggia, potete visitare bellissime chiese, basiliche e musei e quindi fare una vacanza culturale e infine potete anche fare una vacanza culinaria perché in questa città si mangia e si beve molto bene. ...The full transcript of this Episode is available via "Luisa's learn Italian Premium" - das komplette Transcript / die Show-Notes zu allen Episoden sind über Luisa's Podcast Premium verfügbar. Den Shop mit allen Materialien zum Podcast finden Sie unter https://premium.il-tedesco.itLuisa's Podcast Premium ist kein Abo - sie erhalten das jeweilige Transscript/die Shownotes sowie zu den Grammatik Episoden Übungen die Sie "pro Stück" bezahlen (ab 25ct). Mehr info unter www.il-tedesco.it bzw. https://www.il-tedesco.it/premiumPer imparare l'italiano - to learn Italian - um Italienisch zu lernen: https://il-tedesco.it Mehr Info unter https://www.il-tedesco.it/premiumRoyalty free music from https://www.FesliyanStudios.comLicense acquired via Donation Purchase License Code: a5a4df71-1839-4960-b2d2-e27ba1681e77

The Gentleman Ultra
Interview with Tobias Jones, journalist, writer and author of 'Ultra: The Underworld of Italian Football'.

The Gentleman Ultra

Play Episode Listen Later Nov 16, 2022 38:26


In this episode of TGU podcast host Frank Risorto sits down for a chat with writer and journalist Tobias Jones. Frank and Tobias talk about Tobias's award winning book 'Ultra: The Underworld of Italian Football' and much more. Tobias talks about the collective and shared experience of the Ultra movement, the history of the Ultras in Italy and how it has evolved over the years for better and worse, following Cosenza all over Italy and learning to love the unorganised chaotic nature of the Cosenza Ultras, the process behind the book and its backstory, the matchday experience in Italy as well as touching on his charity and community work in the UK with Windsor Hill Wood and Shepton Mallet Community Woodland as well as Common Home in Parma, Italy. Enjoy the conversation. You can find Tobias on Twitter at @Tobias_Italia, his work at http://www.tobias-jones.com/ and Common Home on Twitter @CommonHomeParma. You can find Frank on Twitter at @SerieA_Aust. You can find The Gentleman Ultra on Twitter @GentlemanUltra. Please don't forget to rate, review and share the podcast and thanks for listening. Enjoy your Calcio!

Opening Arguments
OA648: More from the Right Wing War on Free Speech

Opening Arguments

Play Episode Listen Later Nov 15, 2022 62:33


Today we get a breakdown on a few cases in which right wing goons are seeking to shut down free speech and freedom of the press in a pretty major way. AND they are finding success in our broken courts. Dershowitz v. CNN and Trump v. CNN. It also gives Andrew a chance to fawn over the Onion Amicus Brief that so many of you requested us to go over! Links: Dersh v CNN motion for summary judgment, Novak v. City of Parma, Novak v. City of Parma, 33 F.4th 296 6th circuit opinion, Novak cert petition, Onion's amicus brief

The Jeremiah Show
Triggered by Twitter

The Jeremiah Show

Play Episode Listen Later Nov 7, 2022 40:35


Bill and Morgan recap a lot of their weekend, plus Bill finally watched "The Black Phone" and Morgan has a complete recap of the Selena Gomez documentary.  How did Bill manage to screw up Daylight Savings Time at his house?  And when can we stop changing our clocks twice a year?  Troy from Parma has been using a designated driver when he hits the town...responsible, right??  Well, not exactly....when you find out WHO he's using as his DD!!  Also, Battle of the Burbs, and find out why Bill got triggered because of the Twitter layoffs last week.  What's the unusual way you got fired from a job....and Morgan's fiance David might have had the best story!  

The City Club of Cleveland Podcast
A Conversation with Representative Jeff Crossman

The City Club of Cleveland Podcast

Play Episode Listen Later Nov 2, 2022 60:00


Leading up to the election on November 8, 2022, The City Club of Cleveland extended invitations to the candidates running for Ohio Attorney General. Join us for a VIRTUAL City Club forum to hear from Democratic candidate, Representative Jeff Crossman. His opponent, the incumbent Attorney General Republican Dave Yost, declined our invitation.rnrnRepresentative Jeff Crossman began his first term serving the Ohio House of Representatives in January 2019. He is currently serving his second term and represents the 15th Ohio House District comprised primarily of Parma, Brooklyn Heights, Cuyahoga Heights, and part of southwest Cleveland.rnrnJeff was born in the small town of Wickliffe, Ohio, and earned his Bachelor's degree from the University of Mount Union and a Master's Degree from the University of Akron. He is a practicing attorney, with over 20 years of experience practicing in the private sector, and earned his law degree from Cleveland-Marshall College of Law. Before joining the Ohio House, Jeff served as a Parma City Councilman for five years.

Post Reports
How the war in Ukraine is shaping Ohio's Senate race

Post Reports

Play Episode Listen Later Oct 31, 2022 21:03


The war in Ukraine may be thousands of miles away from Ohio. But because of the state's large Ukrainian population, the war could determine who wins the state's open Senate seat: isolationist Republican J.D. Vance or Democratic Rep. Tim Ryan.Read more:Republican J.D. Vance and Democratic Rep. Tim Ryan are in a tight race over an open Senate seat in Ohio, a state Donald Trump carried in 2020. While both candidates have talked plenty about domestic matters, there is one issue that could swing the race: what America's role in the war in Ukraine should be. Ohio has a large population of people descended from Eastern Europe. One small city — Parma — is home to the largest community of Ukrainian Americans in the state. While these voters often support conservatives, Vance's opposition to providing more aid to Ukraine in the war with Russia has caused many of them to reconsider. Reporter Cara McGoogan joins us on “Post Reports” to discuss what she learned when she spoke to voters in Ohio.

A History of Italy » Podcast
F100: 04 The March on Rome

A History of Italy » Podcast

Play Episode Listen Later Oct 28, 2022 30:22


One hundred years ago, a series of events between 24th and 31st October 1922 culminated in Fascist leader Benito Mussolini taking power in what is known as "The March on Rome". Did the Black shirts actually take Rome by force? Why did the government not put a stop to the events? Together we will take a look at the fateful days in which Fascism came to power.

Fides Podcast
Jolene Austin for OH-14; Pro-Abortion Catholics?? "Does the Democrat Party Represent Your Values, Parma, OH"

Fides Podcast

Play Episode Listen Later Oct 27, 2022 32:28


Join me as I speak to Jolene Austin, Republican candidate for the Ohio House-14.  She is on to talk about why she is running and why her district needs to vote Republican.  I also discuss her opponent, Sean Brennan, as a pro-abortion Catholic.  I also ask Democrats in Parma, OH, if today's Democrat party represents who you are.

Comedian of Law
Hilarious Amicus Brief in Defense of Parody & Supreme Court Denies Trump a Special Master

Comedian of Law

Play Episode Listen Later Oct 21, 2022 68:00


In today's podcast episode, Joel and Chris talk about the Supreme Court rejection of Trump's request for a special master in the Mar-a-lago case. They talk about humor in the courtroom and the right to engage in parody. They review recent case Novak v. City of Parma dealing with a joke at the expense of the police and the Onion's amicus brief in response to the case that skillfully mixes law and humor. They also talk Ted Cruz's campaign financing.  In Courtroom Quarterback (beginning minute 48:15), Joel and Chris review the latest from the NFL.