Podcasts about Giuseppe

Get ready to dive into the vibrant world of CM Calabria, the last Council Meeting held in the land of sunshine, good food, and even better people! In this episode, we sit down with two of our favorite organizers, Emanuele and Giuseppe, to go behind the scenes of hosting one of ESTIEM's biggest events. We discuss everything from the intense preparation process and the craziest moments they remember to the biggest challenges they overcame. Tune in for their advice to other Local Groups considering hosting, and find out why they agree that hosting a CM is a unique mix of hard work and much of fun - which, as we know, is exactly what ESTIEM is all about!

Check the full tracklist for this episode here: Tujamo, Relova - Jump Into The Bag Pretty Pink - Young Steff da Campo - Break It Down Adriatique, Argy - RACER Martin Garrix, R3hab, Skytech - Voodoo Martin Garrix, JEX - Told You So (Brooks Remix) Joa - No Games Agents of Time, Ceres - Baby Kasablanca - Time Ilan Bluestone, Giuseppe de Luca - This Town Mike Candys - Afterparty Kazden, Jasskall, Cube Cartel - Thunder Cassian, Yotto, Da Hool - Love Parade Dirty Signal - Feel It Kohey, Matt Dybal - All You've Got Tai Woffinden, Saltwater - The Legacy Ely Oaks, Lavinia - Money Made Me A Savage (Calabria) Marlo, Voolgarizm, TBR - Breathe Again (TBR Remix) Lilly Palmer - TECHY MF BEAUZ, Flawx, Robbe - Immigrant Song - Techno Mix Yellow Claw - Touch It

La Juventus è vicinissima all'ufficializzazione del suo sesto allenatore in cinque anni: Luciano Spalletti è stato infatti scelto per cercare di raddrizzare la rotta di una nave che sotto la guida di Tudor sembrava imbarcare troppa acqua. Samuele e Giuseppe ci hanno accompagnato attraverso questo e altri temi calcistici dell'ultima settimana.

"Colpo di Tacco" con Alessandro Santarelli, Vincenzo Marangio e Claudia Santarelli, cronaca di Antonio Paolino commento di Samuel Tafesse e Gianni Balzarini Ospiti: Tipster Farm, Giuseppe Lo Porto (in collegamento dallo Stadium)

My guest today is GIUSEPPE RIBAUDO! His creative path feels like a storybook for modern makers. Better known to the quilting world as Giucy Giuce, he grew up on Long Island, New York, in a bustling Sicilian-American household where food, family, and creativity were always close at hand. He learned to sew from his grandmother — a talented seamstress with a sharp eye and even sharper expectations. He is known for his stunning fabric collections, his storytelling through color and pattern, and the modern, moody aesthetic that has inspired makers to get quilting! We'll talk about the family roots that shaped his creativity, his leap into the fabric industry, and the inspiration behind his fabric collections including, Enrapture his first collection with FreeSpirit Fabrics and what's coming soon!Find Giuseppe right here: https://www.giucygiuce.com/Quilter on Fire Website - https://quilteronfire.com/OLISO IRONS - Host of the Quilter on Fire Podcast Lounge each year at QuiltCon!BUY YOUR OWN OLISO MINI PROJECT IRON RIGHT HERESquare One Textile Art WorkshopJoin Brandy's email listFree Quilter on Fire Holiday Table Runner VIDEOSUPPORT THE PODCAST by becoming a Quilter on Fire Podcast Angel for as little as $3 per week.Support the showThank you for listening to the Quilter on Fire Podcast.

A TUTTA C con Luca Bargellini. Ospite: Giuseppe Pillon, allenatore

A TUTTA C con Luca Bargellini. Ospiti: Matteo Ferri, Simone Tiribocchi, Giuseppe Pillon

Viaggio intorno al podio paralimpico, quelle che facciamo oggi a Olympia. Scatteranno il 6 marzo, i Giochi Paralimpici Invernali di MilanoCortina2026, fino al 15 marzo. Ne parliamo oggi con un paratleta che il sogno paralimpico ha cominciato a inseguirlo dieci anni fa, ma come nuotatore; l'ha poi raggiunto - a livello estivo - come triatleta a Parigi2024, sfiorando anche lì quel podio che aveva invece conquistato nello sci di fondo alle Paralimpiadi Invernali di Pechino2022. È la parabola di Giuseppe 'Beppe' Romèle, che si racconta a Olympia. Nella seconda parte della puntata parleremo proprio di chi un podio - olimpico o mondiale - l'ha sfiorato o accarezzato, senza riuscire - a volte - a salirci. Ma come ha più volte sottolineato il Presidente della Repubblica, Sergio Mattarella, anche i quarti posti hanno il loro valore etico e sportivo. Al punto da meritarsi un libro, "Quarti di Gloria" (LabDfg editore): ne parliamo con gli autori, i giornalisti Serena Sartini e Gerardo De Vivo.

Conducono Davide e Giuseppe

Il cervello guida i nostri pensieri, emozioni, sogni. Coordina il corpo, custodisce la memoria e ci fa immaginare il futuro. Ed è proprio questo organo meraviglioso ad essere protagonista di una puntata speciale del PoretCast dal titolo “Senti che cervello”. Un viaggio alla scoperta del cervello tra filosofia e scienza, un dialogo tra il divulgatore filosofico BarbaSophia e gli esperti dell'Istituto Neurologico Carlo Besta: Prof. Giuseppe Lauria Pinter, Direttore Scientifico del Besta e la Dott.ssa Licia Grazzi, Responsabile SS Centro Cefalee dell'Istituto Besta. La puntata è stata promossa da CBDIN ODV, con il coordinamento scientifico e con il patrocinio dell'Istituto Neurologico Carlo Besta, con il patrocinio di Regione Lombardia e Rete Città sane OMS, ed è realizzato con il contributo non condizionato di Lundbeck Italia. Una produzione Corax. Learn more about your ad choices. Visit megaphone.fm/adchoices

Giuseppe Anastasi torna con “Non mi dire mai la verità”, un brano cantautorale delicato e intenso che riflette sul bisogno umano di illusione. Una richiesta sottovoce all'altro: fingere felicità, fingere attenzione, fingere che il mondo stia andando per il verso giusto. Non per superficialità, ma per sopravvivenza emotiva. Attraverso un arrangiamento misurato e sonorità essenziali, […]

In questa puntata di Start parliamo di una nuova alleanza per lo spazio, con Leonardo, Airbus e Thales che hanno stretto un accordo per unire forze e tecnologie e rendere l'Europa più autonoma in un settore dominato da giganti come SpaceX; torniamo a discutere di ora solare, con il premier spagnolo Pedro Sanchez che ha rilanciato l'idea di abolire del tutto il cambio semestrale, tema che tornerà ufficialmente all'ordine del giorno del Consiglio europeo di fine ottobre; continuiamo il nostro viaggio tra le scoperte scientifiche andando in Germania, dove un gruppo di neuroscienziati dell'Università di Colonia ha scoperto un circuito nel cervello che aiuta a calmare l'ansia senza bloccare comportamenti vitali come mangiare o esplorare; infine, ti racconto la storia di Giuseppe e sua moglie. Se vuoi dirmi le difficoltà e le sfide che, come giovane, incontri nella tua vita quotidiana o, semplicemente, la tua opinione sulle notizie che hai ascoltato oggi, puoi mandare un'email a angelica.migliorisi@ilsole24ore.comPer approfondire le notizie di oggi:- Learn more about your ad choices. Visit megaphone.fm/adchoices

LOUNGE CINEMATICA RADIO | SEASON 6 Episode 6x05 Released 24-10-25 01 .Rumba Tres - Un Te Quiero (Javier Di Granti Extended Mix) | Belter 70.020 ©1976 02. Giuseppe de Luca - Mille Peccati... Nessuna Virtù (Original Soundtrack) | CAM Sugar UME ©2025* 03. Elsio Mancuso & Berto Pisano - Nude Per L'Assassino (Original Soundtrack) | Four Flies Records FLIES 75 ©2025* 04. Nico Fidenco - Bruna, Formosa, Cerca Superdotato (Original Soundtrack) | CAM Sugar UME ©2025* *Available for the first time ever Selected, edited and mastered by JAVIER DI GRANTI Distributed on APPLE PODCASTS, AMAZON MUSIC, YOUTUBE MUSIC, IVOOX ©2025

Quanto costa davvero l'incertezza normativa?In questa puntata di LeoniFiles – Le Interviste, Carlo Stagnaro parla con Giuseppe L'Abbate ( ex Sottosegretario all'Agricoltura) dei nodi irrisolti della legislazione italiana sulla coltivazione e trasformazione della canapa industriale, per capire come la Legge 242/2016 sia diventata un caso emblematico di caos normativo che blocca un settore ad alto potenziale per gli agricoltori e per l'economia italianaLa via d'uscita? Liberalizzare, con norme certe. Perché in Italia, senza regole chiare, sarà sempre più facile coltivare dubbi che imprese.00:00 - Gli argomenti della puntata1:16 – Un ospite sul campo: Giuseppe L'Abbate2:06 – Come nasce la legge 242/2016 e cosa doveva fare (in teoria)5:14 – La confusione normativa: chi decide cosa è legale?17:47 – I costi dell'incertezza: quando la legge ferma l'economia18:49 – Agricoltori tra burocrazia e ricorsi: la teoria che blocca la pratica28:27 – Controlli, sequestri e paradossi all'italiana30:35 – Cosa servirebbe davvero per rimettere ordine35:25 – Conclusioni: buon senso e libertà sono sempre utiliPreferisci seguire su YouTube?

Ricardo Giuseppe Mereu - a cura di Paolo Massari

Have a Social with the Saints! Receive encouragement for your daily life as we meet & discuss this professor and physician. Who was he? How will he help and inspire you? Be encouraged and inspired for your daily life! Get a free quote card, pamphlet & phone wallpaper of St. Giuseppe Moscati here. We invite you to share them with friends and family. We want to hear from you! What struck you about St. Giuseppe Moscati? Please send us your feedback to join the conversation by email at ministry@pilgrimcenterofhope.org The official Socials with the Saints theme song is “Hero's Ascent” by Chris Haugen. Used with permission. Thanks for listening, and remember, you are never alone in the communion of the saints! May God bless you. Help us spread hope!

In questa puntata di Start focus sulla Sanità, che conquista 2,4 miliardi in più nel 2026 portando così il Fondo sanitario nazionale con le risorse già stanziate dalla manovra dell'anno scorso a sfiorare i 143 miliardi; spazio poi al nuovo bonus elettrodomestici, con il via alle procedure di registrazione dei prodotti da parte dei produttori; analizziamo anche gli aumenti delle sigarette, che non comporteranno alcuno shock per il mercato del fumo ma che hanno l'obiettivo di sfavorire il mercato del contrabbando; infine, ti racconto la storia di Giuseppe. Se vuoi dirmi le difficoltà e le sfide che, come giovane, incontri nella tua vita quotidiana o, semplicemente, la tua opinione sulle notizie che hai ascoltato oggi, puoi mandare un'email a angelica.migliorisi@ilsole24ore.com Per approfondire le notizie di oggi: - Learn more about your ad choices. Visit megaphone.fm/adchoices

We're privileged to host a true franchise veteran, a coach, author, speaker, and consultant who has made it his mission to simplify the often-complex world of franchising. Giuseppe Grammatico excels at guiding candidates not just to a business model, but to the "business smile"—that perfect fit that suits their desired lifestyle.Giuseppe Grammatico is a franchise veteran, coach, author, speaker & consultant who simplifies the process of franchising and excels at guiding his candidates to the business model that best suits their desired lifestyle. His greatest joy is helping people realize the American dream and sharing the freedom that comes from franchising. With over twenty years in franchising, both as an owner and consultant, Giuseppe has seen firsthand how franchising can be a launchpad for entrepreneurship and freedom and I'd love to share that perspective with your listeners. Giuseppe's approach centers on simplifying what can be a complex journey. He has guided more than 200 people into business ownership, many for the first time, using a tailored process to match them with opportunities that fit their goals. Having built on a foundation of sales, marketing, and management, he is passionate about helping others move past the overwhelm and into confident decisions about their future.CONTACT DETAILS: Email: gg@ggthefranchiseguide.com Company: GG The Franchise GuideWebsite: https://ggthefranchiseguide.com/ Social Media:LinkedIN - https://www.linkedin.com/company/gg-the-franchise-guide Facebook - https://www.facebook.com/GGTheFranchiseGuide Instagram - https://www.instagram.com/ggthefranchiseguide/ Tiktok - https://www.tiktok.com/@ggthefranchiseguide X - https://twitter.com/ggfranchguide Free Book Download: https://ggthefranchiseguide.com/book-landing-page/ Remember to SUBSCRIBE so you don't miss "Information That You Can Use." Share Just Minding My Business with your family, friends, and colleagues. Engage with us by leaving a review or comment on my Google Business Page. https://g.page/r/CVKSq-IsFaY9EBM/review Your support keeps this podcast going and growing.Visit Just Minding My Business Media™ LLC at https://jmmbmediallc.com/ to learn how we can help you get more visibility on your products and services.

Ep. 175Israele-Palestina: cosa manca per arrivare alla pace? Con Giuseppe Sarcina

Giuseppe Grammatico was living the life many dream of—a six-figure salary at JP Morgan. But with a five-hour daily commute and a baby on the way, he realized the "dream" was costing him the one thing that truly mattered: time with his family. He made the terrifying choice to quit his secure corporate job with no business idea, betting everything on a life of freedom. His search led him away from startups and into the world of franchising, where he discovered opportunities beyond just fast food.After building his own successful franchise for 13 years, Giuseppe achieved the time freedom he craved and now works as a franchise coach helping others do the same. In this episode, he sits down with Ryan Atkinson to share his playbook for achieving financial and time freedom. You'll learn how to identify recession-resistant businesses, spot the green flags of a healthy franchise model, and analyze key financial metrics before investing. He also breaks down why strong business systems and discovering your "why" are the ultimate keys to entrepreneurial success.Takeaways:- Your "why" is the most critical driver for entrepreneurship; leaving a six-figure job was about gaining time freedom to be present with family, not just about money.- Franchising extends far beyond fast food, with over 4,000 options in more than 70 industries, providing a viable path to business ownership without needing a unique startup idea.- Prioritize recession-resistant franchise models, such as water and smoke mitigation or essential B2B services, that remain in demand regardless of the economic climate.- A healthy franchise will vet you for a mutual fit rather than just giving you a sales pitch. They should have a clear vision for the future and be transparent about their systems.- Thoroughly vet a franchise through "validation" by speaking directly with existing franchisees. Ask them, "Knowing what you know today, would you do it all over again?"- When evaluating financials, look beyond profit margins and analyze the Average Unit Volume (AUV), as a high-volume business can be more profitable than a high-margin one.- A franchise's value lies in its proven, plug-and-play systems. The franchisor should be able to demonstrate their CRM, marketing, and lead generation processes.- The business is the vehicle to achieve your "why." Don't get stuck on finding a business you're "passionate" about; find one that enables the lifestyle you want.- Time freedom isn't immediate. The first year of a new business often requires more work, but it's a necessary sacrifice to build the systems that enable flexibility later on.- Avoid costly mistakes by tracking your marketing spend. Blindly investing without monitoring Key Performance Indicators (KPIs) and return on investment is a recipe for failure.Tags:  Franchise, Entrepreneurship, Business Buying, Home Services, Passive Income, Recession-Proof BusinessResources:Grow your business today: https://links.upflip.com/the-business-startup-and-growth-blueprint-podcast Connect with Giuseppe: https://www.linkedin.com/in/giuseppe-grammatico

“Too many procurement professionals have developed a push energy. If you take that same approach with internal stakeholders, it won't work. We need to develop pull energy — asking questions, listening, and creating a shared vision.” - Giuseppe Conti, Professor, Author of Negotiation + Influence = Success: Quick Lessons to Help You Win in Corporate Life Procurement leaders know how much the field has changed, but the biggest barriers often come from within. As procurement's role expands, it has become essential to influence internally, manage expectations, and go beyond data-driven persuasion. In this Art of Procurement podcast episode, Philip Ideson speaks with Giuseppe Conti, a seasoned procurement executive turned business school professor. Giuseppe reveals why internal negotiation is so much tougher than dealing with suppliers, and offers strategies to shift procurement teams from “push” to “pull” influence. If your team's technical skills are strong, but your impact could be greater, this is a must-listen. Giuseppe's practical tools – like a 20-minute, one-page prep template and real-world active listening techniques – will give any procurement leader an edge. In this episode, Giuseppe explains how to: Diagnose and close the gap between perceived and actual listening skills Move from “push energy” to “pull energy” for genuine, lasting influence Set realistic internal stakeholder expectations and avoid common missteps Balance data with emotional intelligence to drive decisions Links: Giuseppe Conti on LinkedIn Negotiation + Influence = Success: Quick Lessons to Help You Win in Corporate Life by Giuseppe Conti Subscribe to This Week in Procurement Subscribe to Art of Procurement on YouTube

Un bellissimo episodio realizzato da Giueppe Pugliese per la Community Edition di Pensieri in codice. NO SPOILER! Se anche tu vuoi parlare di qualche argomento interessante su Pensieri in codice, scrivimi su Telegram o all’indirizzo valerio@pensieriincodice.it Pensieri in codice Puoi trovare Giuseppe Pugliese sul sito https://magnetarman.com/ In particolare, il suo podcast Glitch è disponibile su tutte le piattaforme podcast e su https://magnetarman.com/glitch/ Trovi invece Good Vibrations: sviluppare nell’era dell’AI su https://www.spreaker.com/podcast/good-vibrations-sviluppare-software-nell-era-dell-ai--6747128 Entra a far parte della community Canale Telegram Gruppo Telegram Sostieni il progetto Sostieni tramite Satispay Sostieni tramite Revolut Sostieni tramite PayPal (applica commissioni) Sostieni utilizzando i link affiliati di Pensieri in codice: Amazon, Todoist, Readwise Reader, Satispay Sostenitori di oggi: Edoardo Secco, Carlo Tomas Partner GrUSP (Codice sconto per tutti gli eventi: community_PIC) Schrödinger Hat Crediti Sound design - Alex Raccuglia Voce intro - Maria Chiara Virgili Voce intro - Spad Musiche - Kubbi - Up In My Jam, Light-foot - Moldy Lotion, Creativity, Old time memories Suoni - Zapsplat.com Cover e trascrizione - Francesco Zubani

Was sollen wir tun?-Giuseppe Mirabelli-19.10.2025

Il volontario venne condannato in primo grado nel dicembre 2017 per omicidio colposo. Ora, a dodici anni di distanza dall'incidente che provocò la morte dell'85enne di Montecchio Maggiore, la Corte d'Appello ha accolto la tesi della difesa sull'imprevedibilità dell'evento.

Tracklist: 01. Argy, John Cala - BOOM [New World] 02. Joshlane - System Overload [Afterlife] 03. Gus One - Strobelights [Deep Woods] 04. Aldor, PIOTR - In My Heart [Deeper Harmonies] 05. LÜRUM - Save Me [Eccentricity] LIGHT SIDE TRACK 06. Krevix - Afterlight [Deeper Harmonies] 07. Beholder & Seb Hennig - Never Alone [Deeper Harmonies] 08. nilsix, Orjan Nilsen, and Mark Sixma - Blast From The Past [Dreamstate Records] 09. Fedo - Hear Me Now [Find Your Harmony] 10. Cristoph & Diana Miro - Echoes [Interstellar] 11. Andrew Rayel pres. ARISEY feat. Freddie Elmberg - Reverie [Find Your Harmony] 12. Adam Sellouk & Zerky - Touch It [Spinnin] 13. Alexander Popov, U-Jeen & Vera Novak - Toca's Miracle [Interplay] 14. K3SS, Gabi Gray - Dont Let go [Rising HRMNY] 15. DIM3NSION - Metamorphosis (RAYEL Remix) [Find Your Harmony] FAVORITE OF THE MOMENT 16. Andrew Rayel feat. Darla Jade - Promise Me (Club Mix) [Find Your Harmony] 17. Ilan Bluestone & Giuseppe de Luca - This Town (Club Mix) [Anjunabeats] 18. Giuseppe Ottaviani - Keep Your Dreams Alive (Darren Porter Remix) [Dreamstate Records] 19. Claudiu Adam & That Girl - You Are Enough [Rising HRMNY] 20. Talla 2XLC, York, Angel City - Euphoria [That's Trance] 21. Robbie Seed & Yoli Rose - Vanishing [Find Your Harmony] 22. Doppenberg - Starlight [Find Your Harmony] 23. Ferry Corsten & Deepest Blue - Deepest Blue [Armada] 24. Driftmoon x XiJaro & Pitch - Rise Again [Black Hole] 25. Cresta - Devil Of Acid [Outburst] 26. A.R.D.I. - On The Other Side [Find Your Harmony] 27. Daxson & Clara Yates - Turn Back [Black Hole] 28. 4YU & LONG PLAY - FUEGO [Rising HRMNY] 29. Armin van Buuren & Sacha - Set Me Free (Rising Star Remix) [Armada] 30. David Forbes - Away [Who's Afraid of 138?!] 31. Oskah & David Chouman - The Call [Reaching Altitude] DARK SIDE TRACK 32. Marco V - Simulated (Olly James Remix) [High Contrast] CLASSIC SELECTION 33. Ferry Corsten pres. Gouryella - Neba [Flashover]

Dr. Hope Rugo and Dr. Giuseppe Curigliano discuss recent developments in the field of bispecific antibodies for hematologic and solid tumors, including strategies to optimize the design and delivery of the immunotherapy. TRANSCRIPT Dr. Hope Rugo: Hello and welcome to By the Book, a podcast series from ASCO that features engaging conversations between editors and authors of the ASCO Educational Book. I am your host, Dr. Hope Rugo. I am the director of the Women's Cancers Program and division chief of breast medical oncology at the City of Hope Cancer Center. I am also the editor-in-chief of the Educational Book. Bispecific antibodies represent an innovative and advanced therapeutic platform in hematologic and solid tumors. And today, I am delighted to be joined by Dr. Giuseppe Curigliano to discuss the current landscape of bispecific antibodies and their potential to reshape the future of precision oncology. Dr. Curigliano was the last author of an ASCO Educational Book piece for 2025 titled, "Bispecific Antibodies in Hematologic and Solid Tumors: Current Landscape and Therapeutic Advances." Dr. Curigliano is a breast medical oncologist and the director of the Early Drug Development Division and chair of the Experimental Therapeutics Program at the European Institute of Oncology in Milan. He is also a full professor of medical oncology at the University of Milan. You can find our disclosures in the transcript of this episode. Dr. Curigliano, Giuseppe, welcome and thanks for being here. Dr. Giuseppe Curigliano: Thanks a lot for the invitation. Dr. Hope Rugo: Giuseppe, I would like to first ask you to provide some context for our listeners on how these novel therapeutics work. And then perhaps you could tell us about recent developments in the field of bispecific antibodies for oncology. We are at a time when antibody-drug conjugates (ADCs) are all the rage and, trying to improve on the targeting of specific antigens, proteins, receptors in the field of oncology is certainly a hot and emerging topic. Dr. Giuseppe Curigliano: So, thanks a lot. I believe really it was very challenging to try to summarize all the bispecific antibodies that are under development in multiple solid tumors. So, the first thing that I would like to highlight is the context and the mechanism of action of bispecific antibodies. Bispecific antibodies represent a groundbreaking advancement in cancer immunotherapy, because these engineered molecules have the unique ability to target and simultaneously bind to two distinct antigens. That is why we call them bispecific. So typically, one antigen is expressed on the tumor cell and the other one is expressed on the immune effectors, like T-cell or natural killer cells. So this dual targeting mechanism offers several key advantages over conventional monoclonal antibodies because you can target at the same time the tumor antigen, downregulating the pathway of proliferation, and you can activate the immune system. So the primary mechanism through which bispecific antibodies exert their therapeutic effects are: First, T-cell redirecting. I mean, many bispecific antibodies are designed to engage tumor-associated antigens like epidermal growth factor receptor, HER2, on the cancer cell and a costimulatory molecule on the surface of T-cell. A typical target antigen on T-cell is CD3. So what does it mean? That you activate the immune system, immune cells will reach the tumor bed, and you have a dual effect. One is downregulating cell proliferation, the other one is activation of the immune system. This is really important in hematological malignancies, where we have a lot of bispecifics already approved, like acute lymphoblastic leukemia or non-Hodgkin lymphoma.  The second, in fact, is the engagement of the tumor microenvironment. So, if you engage immune effector cells like NK cells or macrophages, usually the bispecific antibodies can exploit the immune system's ability to recognize and kill the immune cells, even if there is a lack of optimal antigen presentation.  And finally, the last mechanism of action, this may have a role in the future, maybe in the early cancer setting, is overcoming immune evasion. So bispecific antibodies can overcome some of the immune evasion mechanisms that we see in cancer. For example, bispecific antibodies can target immune checkpoint receptors, like PD-L1 and CTLA-4. Actually, there is a bispecific under development in breast cancer that has a dual targeting on vascular endothelial growth factor receptor and on PD-L1. So you have a dual effect at the same time. So, what is really important, as a comment, is we need to focus first on the optimal format of the bispecific, the optimal half-life, the stability, because of course even if they are very efficient in inducing a response, they may give also a lot of toxicities. So in clinical trials already, we have several bispecifics approved. In solid tumors, very few, specifically amivantamab for non-small cell lung cancer, but we have a pipeline of almost 40 to 50 bispecifics under development in multiple solid tumors, and some of them are in the context of prospective randomized trials. Dr. Hope Rugo: So this is really a fascinating area and it's really exciting to see the expansion of the different targets for bispecific antibodies. One area that has intrigued me also is that some of the bispecifics actually will target different parts of the same receptor or the same protein, but presumably those will be used as a different strategy. It's interesting because we have seen that, for example, in targeting HER2. Dr. Giuseppe Curigliano: Oh, yes, of course. You may consider some bispecifics like margetuximab, I suppose, in which you can target specifically two different epitopes of the same antigen. This is really an example of how a bispecific can potentially be more active and downregulating, let us say, a pathway, by targeting two different domains of a specific target antigen. This is an important point.  Of course, not all the bispecifics work this way, because some of the target antigen may dimerize, and so you have a family of target antigen; an example is epidermal growth factor receptor, in which you have HER1, HER2, HER3, and HER4. So some of them can inhibit the dimerization between one target antigen and the other one, in order to exert a more antiproliferative effect. But to be honest, the new generation of them are more targeting two different antigens, one on the tumor and one on the microenvironment, because according to the clinical data, this is a more efficient way to reduce proliferation and to activate the immune system. Dr. Hope Rugo: Really interesting, and I think it brings us to the next topic, which is really where bispecific antibodies have already shown success, and that is in hematologic malignancies where we have seen very interesting efficacy and these are being used in the clinic already. But the expansion of bispecific antibodies into solid tumors faces some key challenges. It's interesting because the challenges come in different shapes and forms. Tell us about some of those challenges and strategies to optimize bispecific antibody design, delivery, patient selection, and how we are going to use these agents in the right kind of clinical trials. Dr. Giuseppe Curigliano: This is really an excellent question because despite bispecific antibodies having shown a remarkable efficacy in hematological malignancies, their application in solid tumors may have some challenges. The first one is tumor heterogeneity. In hematological malignancy, you have a clear oncogene addiction. Let us say that 90% of the cells may express the same antigen. In solid tumors, it is not the same. Tumor heterogeneity is a typical characteristic of solid tumors, and you have high heterogeneity at the genetic, molecular, and phenotypic levels. So tumor cells can differ significantly from one another, even if within the same tumor. And this heterogeneity sometimes makes it difficult to identify a single target antigen that is universally expressed in an hematological malignancy. So furthermore, sometimes the antigen expressed on a tumor cell can be also present on the normal tissue. And so you may have a cross-targeting. So let's say, if you have a bispecific against epidermal growth factor receptor, this will target the tumor but will target also the skin with a lot of toxicity. The second challenge is the tumor microenvironment. The solid tumor microenvironment is really complex and often immunosuppressive. It is characterized by the presence of immunosuppressor cells like the T regulators, myeloid derived suppressor cells, and of course the extracellular matrix. All these factors hinder immune cell infiltration and also may reduce dramatically the effectiveness of bispecific antibodies. And as you know, there is also an hypoxic condition in the tumor. The other challenge is related to the poor tumor penetration. As you know also with antibody-drug conjugate, only 1 to 3% of the drug will arrive in the tumor bed. Unlike hematological malignancies where tumor cells are dispersed in the blood and easily accessible, the solid tumors have a lot of barriers, and so it means that tumor penetration can be very low. Finally, the vascularity also of the tumor can be different across solid tumors. That is why some bispecifics have a vascular endothelial growth factor receptor or vascular endothelial growth factor as a target. Of course, what do we have to do to overcome these challenges? First, we have to select the optimal antigen. So knowing very well the biology of cancer and the tumor-associated antigens can really select a subgroup of epitopes that are specifically overexpressed in cancer cells. And so we need to design bispecifics according to the tumor type. Second, optimize the antibody format. So there are numerous bispecific antibody formats. We can consider the dual variable domain immunoglobulin, we specified this in our paper. The single chain variable fragments, so FC variable fragments, and the diabodies that can enhance both binding affinity and stability. And finally, the last point, combination therapies. Because bispecific antibodies targeting immune checkpoint, we have many targeting PD-1 or PD-L1 or CTLA-4, combined eventually with other immune checkpoint inhibitors. And so you may have more immunostimulating effect. Dr. Hope Rugo: This is a fascinating field and it is certainly going to go far in the treatment of solid tumors. You know, I think there is some competition with what we have now for antibody-drug conjugates. Do you see that bispecifics will eventually become bispecific ADCs? Are we going to combine these bispecific antibodies with ADCs, with chemotherapy? What is the best combination strategy do you think looking forward? Dr. Giuseppe Curigliano: So, yes, we have a bispecific ADC. We have actually some bispecifics that are conjugated with a payload of chemotherapy. Some others are conjugated with immunoactivation agents like IL-2. One of the most effective strategies for enhancing bispecific activity is the combination therapy. So which type of combination can we do? First, bispecific antibodies plus checkpoint inhibitors. If you combine a bispecific with an immune checkpoint, like anti-PD-1, anti-PD-L1, or anti-CTLA-4, you have more activity because you have activation of T-cells, reduction of immunosuppressive effect, and of course, the capability of this bispecific to potentiate the activity of the immune checkpoint inhibitor. So, in my opinion, in a non-small cell lung cancer with an expression of PD-L1 more than 50%, if you give pembrolizumab plus a bispecific targeting PD-L1, you can really improve both response rate and median progression-free survival.  Another combination is chemotherapy plus bispecific antibodies. Combining chemotherapy with bispecific can enhance the cytotoxic effect because chemotherapy induces immunogenic cell death, and then you boost with a bispecific in order to activate the immune system. Bispecific and CAR T-cells, until now, we believe that these are in competition, but this is not correct. Because CAR T-cells are designed to deliver an activation of the immune system with the same lymphocytes engineered of the patients, with a long-term effect. So I really do not believe that bispecifics are in competition with CAR T-cells because when you have a complete remission induced by CAR T-cell, the effect of this complete remission can last for years. The activity of a bispecific is a little bit different. So there are some studies actually combining CAR T-cells with bispecifics. For example, bispecific antibodies can direct CAR T-cells in the tumor microenvironment, improving their specificity and enhancing their therapeutic effect.  And finally, monoclonal antibody plus bispecific is another next generation activity. Because if you use bispecific antibodies in combination with existing monoclonal antibodies like anti-HER2, you can potentially increase the immune response and enhance tumor cell targeting. In hematological malignancies, this has been already demonstrated and this approach has been particularly effective. Dr. Hope Rugo: That's just so fascinating, the whole idea that we have these monoclonal antibodies and now we are going to add them to bispecifics that we could maybe attach on different toxins to try and improve this, or even give them with different approaches. I suppose giving an ADC with a bispecific would sort of be similar to that idea of giving a monoclonal antibody with the bispecific. So it is certainly intriguing. We also will need to understand the toxicity and cost overall and how we are going to use these, the duration of treatment, the assessment of biomarkers. There are just so many different aspects that still need to be explored.  And then with that idea, can you look ahead five or ten years from now, and tell us how you think bispecific antibodies will shape our next generation cancer therapies, how they will be incorporated into precision oncology, and the new combinations and approaches as we move forward that will help us tailor treatment for patients both with solid tumors and hematologic malignancies? Are we going to be giving these in early-stage disease in solid tumors? So far, the studies are primarily focusing on the metastatic setting, but obviously one of the goals when we have successful treatments is to move them into the early stage setting as quickly as possible. Dr. Giuseppe Curigliano: Let us try to look ahead five years rather than ten years, to be more realistic. So, personally I believe some bispecifics can potentially replace current approaches in specifically T-cell selected population. As we gather more data from ongoing clinical trials and we adopt a deeper understanding of the tumor immuno microenvironment, of course we may have potentially new achievement. A few days ago, we heard that bispecifics in triple negative breast cancer targeting VEGF and PD-L1 demonstrated an improvement in median progression-free survival.  So, how to improve and to impact on clinical practice both in the metastatic and in the early breast cancer setting or solid tumor setting? First, personalized antigen selection. So we need to have the ability to tailor bispecific antibody therapy to the unique tumor profile of individual patients. So the more we understand the biology of cancers, the more we will be able to better target. Second, bispecific antibodies should be combined. I can see in the future a potential trial in which you combine a bispecific anti-PD-L1 and VEGF with immune checkpoint inhibitor selected also to the level of expression of PD-L1, because integration of antibody bispecific with a range of immunotherapies, and this cannot be only immune checkpoint inhibitors, but can be CAR T-cells, oncolytic viruses, also targeted therapy, will likely be a dominant theme in the coming years. This combination will be based on the specific molecular and immuno feature of the cancer of the patient.  Then we need an enhanced delivery system. This is really important because you know now we have a next generation antibody. An example are the bicyclic. So you use FC fragment that are very short, with a low molecular weight, and this short fragment can be bispecific, so can target at the same time a target antigen and improving the immune system. And so the development of this novel delivery system, including also nanoparticles or engineered viral vectors, can enhance the penetration in the tumor bed and the bioavailability of bispecific antibodies. Importantly, we need to reduce toxicity. Until now, bispecifics are very toxic. So the more we are efficient in delivering in the tumor bed, the more we will reduce the risk of toxicity. So it will be mandatory to reduce off-target effects and to minimize toxicity.  And finally, the expansion in new indication. So I really believe you raised an excellent point. We need to design studies in the neoadjuvant setting in order to better understand with multiple biopsies which is the effect on the tumor microenvironment and the tumor itself, and to generate hypotheses for potential trials or in the neoadjuvant setting or in those patients with residual disease.  So, in my opinion, as we refine design, optimize patient selection, and explore new combination, in the future we will have more opportunity to integrate bispecifics in the standard of care. Dr. Hope Rugo: I think it is particularly helpful to hear what we are going to be looking for as we move forward to try and improve efficacy and reduce toxicity. And the ability to engineer these new antibodies and to more specifically target the right proteins and immune effectors is going to be critical, of course, moving forward, as well as individualizing therapy based on a specific tumor biology.  Hearing your insights has been great, and it really has opened up a whole area of insight into the field of bispecifics, together with your excellent contribution to the ASCO Educational Book. Thank you so much for sharing your thoughts and background, as well as what we might see in the future on this podcast today. Dr. Giuseppe Curigliano: Thank you very much for the invitation and for this excellent interview. Dr. Hope Rugo: And thanks to our listeners for joining us today. You will find a link to the Ed Book article we discussed today in the transcript of this episode. It is also, of course, on the ASCO website, as well as on PubMed. Please join us again next month on By the Book for more insightful views on the key issues and innovations that are shaping modern oncology. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement. Follow today's speakers:       Dr. Hope Rugo  @hope.rugo  Dr. Giuseppe Curigliano @curijoey Follow ASCO on social media:       @ASCO on X (formerly Twitter)       ASCO on Bluesky      ASCO on Facebook       ASCO on LinkedIn       Disclosures:      Dr. Hope Rugo:   Honoraria: Mylan/Viatris, Chugai Pharma  Consulting/Advisory Role: Napo Pharmaceuticals, Sanofi, Bristol Myer  Research Funding (Inst.): OBI Pharma, Pfizer, Novartis, Lilly, Merck, Daiichi Sankyo, AstraZeneca, Gilead Sciences, Hoffman La-Roche AG/Genentech, In., Stemline Therapeutics, Ambryx  Dr. Giuseppe Curigliano: Leadership: European Society for Medical Oncology, European Society of Breast Cancer Specialists, ESMO Open, European Society for Medical Oncology Honoraria: Ellipses Pharma Consulting or Advisory Role: Roche/Genentech, Pfizer, Novartis, Lilly, Foundation Medicine, Bristol-Myers Squibb, Samsung, AstraZeneca, Daiichi-Sankyo, Boerigher, GSK, Seattle Genetics, Guardant Health, Veracyte, Celcuity, Hengrui Therapeutics, Menarini, Merck, Exact Sciences, Blueprint Medicines, Gilead Sciences Speakers' Bureau: Roche/Genentech, Novartis, Pfizer, Lilly, Foundation Medicine, Samsung, Daiichi Sankyo, Seagen, Menarini, Gilead Sciences, Exact Sciences Research Funding: Merck Travel, Accommodations, Expenses: Roche/Genentech, Pfizer, Daiichi Sankyo, AstraZeneca      

Il processo che coinvolge Leonarda Cianciulli e suo figlio Giuseppe Pansardi volge al termine, ma non prima di aver visto l'imputata dimostrare il solito, ambiguo comportamento, tra lucidità e follia. E soprattutto non prima di aver ascoltato altri testimoni, che gettano luci, o forse ombre, differenti sulla storia raccontata in prima persona da Leonarda. Quella storia che per molti è genuina e dimostra il suo disagio psichico, mentre per altrettanti è frutto di una mente scaltra e manipolatrice. Il verdetto non lenirà i dubbi, tutt'altro, ma è possibile dopo decenni scoprire la verità sui delitti della saponificatrice?Una produzione Think about Science: thinkaboutscience.comCon: Massimo Polidoro e Giulio Niccolò Carlone; Video editing: Elena Mascolo, Fotografia: Claudio Sforza; Musiche: Marco Forni; Logo e animazioni: Zampediverse; Social - Comunicazione: Giacomo Vallarino - Grafiche: Roberta Baria; Distribuzione audio: Enrico Zabeo; Titoli: Jean SevillaÈ ARRIVATO IL MIO NUOVO LIBRO: "Una vita ben spesa. Trovare il senso delle cose con Leonardo, Einstein e Darwin": https://amzn.to/4leRDOR LEGGI UN ESTRATTO: https://bit.ly/4jRHXIN LEGGI la mia graphic novel: "Figli delle stelle" (con Riccardo La Bella, per Feltrinelli Comics): https://amzn.to/47YYN3KLEGGI: "Sherlock Holmes e l'arte del ragionamento" (Feltrinelli), il mio ultimo libro: https://amzn.to/3UuEwxSLEGGI: "La meraviglia del tutto" l'ultimo libro di Piero Angela che abbiamo scritto insieme: https://amzn.to/3uBTojAIscriviti alla mia NEWSLETTER: L' "AVVISO AI NAVIGANTI": https://mailchi.mp/massimopolidoro/avvisoainavigantiAderisci alla pagina PATREON, sostieni i miei progetti e accedi a tanti contenuti esclusivi:   /massimopolidoroScopri i miei Corsi online: "L'arte di Ragionare", "Psicologia dell'insolito", "L'arte di parlare in pubblico" e "l'Arte del Mentalismo": https://www.massimopolidorostudio.comPER APPROFONDIRELe musiche sono di Marco Forni e si possono ascoltare qui: https://hyperfollow.com/marcoforniLEGGI i miei libri: "Sherlock Holmes e l'arte del ragionamento": https://amzn.to/3UuEwxS"La meraviglia del tutto" con Piero Angela: https://amzn.to/3uBTojA"La scienza dell'incredibile. Come si formano credenze e convinzioni e perché le peggiori non muoiono mai": https://amzn.to/3Z9GG4W"Geniale. 13 lezioni che ho ricevuto da un mago leggendario sull'arte di vivere e pensare": https://amzn.to/3qTQmCC"Il mondo sottosopra": https://amzn.to/2WTrG0Z"Pensa come uno scienziato": https://amzn.to/3mT3gOiL' "Atlante dei luoghi misteriosi dell'antichità": https://amzn.to/2JvmQ33"La libreria dei misteri": https://amzn.to/3bHBU7E"Grandi misteri della storia": https://amzn.to/2U5hcHe"Leonardo. Genio ribelle": https://amzn.to/3lmDthJE qui l'elenco completo dei miei libri disponibili: https://amzn.to/44feDp4Non perdere i prossimi video, iscriviti al mio canale: https://goo.gl/Xkzh8ARESTIAMO IN CONTATTO:Ricevi l'Avviso ai Naviganti, la mia newsletter settimanale: https://mailchi.mp/massimopolidoro/avvisoainavigantie partecipa alle scelte della mia communitySeguimi:Patreon: massimopolidoroCorsi: massimopolidorostudio.comInstagram: @massimopolidoroPagina FB: Official.Massimo.Polidoro X: @massimopolidoro  Sito: http://www.massimopolidoro.comQuesta descrizione contiene link affiliati, il che significa che in caso di acquisto di qualcuno dei libri segnalati riceverò una piccola commissione (che a te non costerà nulla): un piccolo contributo per sostenere il canale e la realizzazione di questi video. Grazie per il sostegno!

First episode of the Progressions. Monthly journey through the sound of trance and progressive. One journey, infinite sound. ⚡️Like the Show? Click the [Repost] ↻ button so more people can hear it!

Fresh from his adventures in Ibiza, Markus Schulz returns home for another studio edition of Global DJ Broadcast. At the center of this week's show is the release of his brand new single under his Dakota alias, What the Night Gave Me - originally crafted for In Search of Sunrise 21: The Nocturnal Voyage, and now available to stream from this Friday. The broadcast also features powerful new music from Miss Monique, Danny Avila & Rome Fortune, Above & Beyond and Matt Fax, along with a special guest mix from American techno powerhouse Sam WOLFE. Markus rounds out the show with a pulsating afterhours finale featuring Pleasurekraft, HI-LO, and Weska.   The Essentials with Markus Schulz 01. Miss Monique, HRRTZ & Jantine - Is Anyone There? 02. KASIA & Charles D featuring Sarah de Warren - Psycho 03. DIEGO SAN DIEGO x Alec Monopoly - Tequila 04. Above & Beyond and Zoe Johnston - Quicksand (Don't Go) (Sultan + Shepard Remix) 05. Markus Schulz presents Dakota - What the Night Gave Me [Down the Rabbit Hole] 06. Fonzerelli - Homeward Bound [In Bloom] 07. Nicolas Viana - Blaze [Deeper Shades] 08. Kasablanca - Audio Machina 09. Dave Neven - Redemption 10. nilsix - Blast from the Past 11. Matt Fax - Origins 12. nümind - Butterflies (Michael Cassette Remix) [A Moment of Sunrise] 13. Markus Schulz x BLR - Ten Seconds Before Sunrise 14. Danny Avila & Rome Fortune - Sweating 15. Mike EFEX - The Unseen Path 16. Mark Otten - Tranquility (Markus Schulz Coldharbour Remix) [Hall of Fame]   Sam WOLFE 01. Danny Avila, Sam WOLFE, HNTR - Yes B!TCH (Sam WOLFE VIP x Graveyard March Intro Edit) 02. Odd Mob - Feel This S**t (Sam WOLFE Flip) 03. Sam WOLFE - ID 04. Zimmz - Higher Consciousness (Sam WOLFE Bootleg) 05. ID 06. Sam WOLFE - The Party 07. Sam WOLFE - ID 08. Sam WOLFE - ID 09. Porter Robinson - Language (Sam WOLFE Remix) 10. Beltran - Smack Yo (Sam WOLFE Bloghouse Remix) 11. Sam WOLFE - Swipe Right 12. Sam WOLFE - Fake Friends   Back with Markus Schulz 17. Pleasurekraft - Simulacra 18. Hollen - No Limits 19. HI-LO - Reese 20. Weska - Holding On 21. Adam Beyer & Julian Jeweil - Loca 22. Timmo - Miami Vice 23. Ilan Bluestone & Giuseppe de Luca - This Town (Club Mix) 24. Shadow Assembly - Elarion  

Italian amari, vermouths, and aperitivo wines have a history spanning back centuries. But these drinks styles are also living categories, continuing to expand in today's cocktail culture. For this episode, we talk withGiuseppe Gallo (IG: @peppegallo1) about the continuing influence of these Italian drinks, and about his contributions to the category: Italicus Rosolio di Bergamotto, Savoia Rosso Americano, and Savoia Orancio, the latter of which took a top award at this year's New Orleans Spirits Competition.Radio Imbibe is the audio home of Imbibe magazine. In each episode, we dive into liquid culture, exploring the people, places, and flavors of the drinkscape through conversations about cocktails, coffee, beer, spirits, and wine. Keep up with us at imbibemagazine.com, and on Instagram, Threads, and Facebook, and if you're not already a subscriber, we'd love to have you join us—click here to subscribe. 

Due uomini, due destini segnati dal coraggio di non piegarsi. Giuseppe Insalaco, ex sindaco di Palermo, e Natale Mondo, poliziotto fedele allo Stato, vengono assassinati a pochi giorni di distanza nel 1988. Entrambi conoscevano troppo, entrambi avevano toccato da vicino gli interessi di Cosa Nostra. In questo video ripercorriamo la loro storia, le indagini, e i legami con la stagione di sangue che travolse Palermo negli anni Ottanta. ISCRIVITI AL CANALE: https://www.youtube.com/@italiamistero?sub_confirmation=1 #italiamistero #GiuseppeInsalaco #NataleMondo #CosaNostra #Mafia #Palermo #TrueCrimeItalia #OmicidiMafiosi #storia #storiavera #perte www.italiamistero.it: https://www.italiamistero.it/

- Premere il tasto PLAY per ascoltare la catechesi del giorno -+ Dal Vangelo secondo Luca +In quel tempo, l'angelo Gabriele fu mandato da Dio in una città della Galilea, chiamata Nazaret, a una vergine, promessa sposa di un uomo della casa di Davide, chiamato Giuseppe. La vergine si chiamava Maria. Entrando da lei, disse: "Ti saluto, o piena di grazia, il Signore è con te".A queste parole ella rimase turbata e si domandava che senso avesse un tale saluto. L'angelo le disse: "Non temere, Maria, perché hai trovato grazia presso Dio. Ecco concepirai un figlio, lo darai alla luce e lo chiamerai Gesù. Sarà grande e chiamato Figlio dell'Altissimo; il Signore Dio gli darà il trono di Davide suo padre e regnerà per sempre sulla casa di Giacobbe e il suo regno non avrà fine".Allora Maria disse all'angelo: "Come è possibile? Non conosco uomo". Le rispose l'angelo: "Lo Spirito Santo scenderà su di te, su te stenderà la sua ombra la potenza dell'Altissimo. Colui che nascerà sarà dunque santo e chiamato Figlio di Dio. Vedi: anche Elisabetta, tua parente, nella sua vecchiaia, ha concepito un figlio e questo è il sesto mese per lei, che tutti dicevano sterile: nulla è impossibile a Dio". Allora Maria disse: "Eccomi, sono la serva del Signore, avvenga di me quello che hai detto". E l'angelo partì da lei.Parola del Signore.

Predicazione espositiva del Pastore Emerito Fred Whitman di Giovanni capitolo 4 versetti 1 a 42. Registrata presso il Centro Evangelico Battista di Perugia il 31 Agosto 2025.Titolo del messaggio: "Gesù e la donna Samaritana"GIOVANNI 4 V1-421 Quando dunque Gesù seppe che i farisei avevano udito che egli faceva e battezzava più discepoli di Giovanni 2 (sebbene non fosse Gesù che battezzava, ma i suoi discepoli), 3 lasciò la Giudea e se ne andò di nuovo in Galilea. 4 Ora doveva passare per la Samaria. 5 Giunse dunque a una città della Samaria, chiamata Sicar, vicina al podere che Giacobbe aveva dato a suo figlio Giuseppe; 6 e là c'era la fonte di Giacobbe. Gesù dunque, stanco del cammino, stava così a sedere presso la fonte. Era circa l'ora sesta. 7 Una donna della Samaria venne ad attingere l'acqua. Gesù le disse: «Dammi da bere». 8 (Infatti i suoi discepoli erano andati in città a comprare da mangiare.) 9 La donna samaritana allora gli disse: «Come mai tu che sei Giudeo chiedi da bere a me, che sono una donna samaritana?» Infatti i Giudei non hanno relazioni con i Samaritani. 10 Gesù le rispose: «Se tu conoscessi il dono di Dio e chi è che ti dice: "Dammi da bere", tu stessa gliene avresti chiesto, ed egli ti avrebbe dato dell'acqua viva». 11 La donna gli disse: «Signore, tu non hai nulla per attingere, e il pozzo è profondo; da dove avresti dunque quest'acqua viva? 12 Sei tu più grande di Giacobbe, nostro padre, che ci diede questo pozzo e ne bevve egli stesso con i suoi figli e il suo bestiame?» 13 Gesù le rispose: «Chiunque beve di quest'acqua avrà di nuovo sete; 14 ma chi beve dell'acqua che io gli darò, non avrà mai più sete; anzi, l'acqua che io gli darò diventerà in lui una fonte d'acqua che scaturisce in vita eterna». 15 La donna gli disse: «Signore, dammi di quest'acqua, affinché io non abbia più sete e non venga più fin qui ad attingere». 16 Egli le disse: «Va' a chiamare tuo marito e vieni qua». 17 La donna gli rispose: «Non ho marito». E Gesù: «Hai detto bene: "Non ho marito", 18 perché hai avuto cinque mariti, e quello che hai ora non è tuo marito; ciò che hai detto è vero». 19 La donna gli disse: «Signore, vedo che tu sei un profeta. 20 I nostri padri hanno adorato su questo monte, ma voi dite che è a Gerusalemme il luogo dove bisogna adorare». 21 Gesù le disse: «Donna, credimi; l'ora viene che né su questo monte né a Gerusalemme adorerete il Padre. 22 Voi adorate quel che non conoscete; noi adoriamo quel che conosciamo, perché la salvezza viene dai Giudei. 23 Ma l'ora viene, anzi è già venuta, che i veri adoratori adoreranno il Padre in spirito e verità; poiché il Padre cerca tali adoratori. 24 Dio è Spirito, e quelli che lo adorano bisogna che lo adorino in spirito e verità». 25 La donna gli disse: «Io so che il Messia (che è chiamato Cristo) deve venire; quando sarà venuto ci annuncerà ogni cosa». 26 Gesù le disse: «Sono io, io che ti parlo!»

Giuseppe Schettini"Cosa?"Ensemble Edizionihttps://www.edizioniensemble.it/prodotto/cosa/Cosa? è la nuova raccolta di Giuseppe Schettini, la prima pubblicata con Ensemble.«In direzione ostinata e contraria rispetto al modus odierno, il flatus di Giuseppe Schettini è invece un accorato grido di dolore, un grido mosso dalla necessità di dire e di raccontare, che si sofferma, però, non sul fatto singolo ma sulla riflessione universale».Giuseppe Schettini è professore ordinario di Campi elettromagnetici presso l'Università “Roma Tre”, dove insegna e svolge attività di ricerca dal 1998. Ha pubblicato numerosi saggi su riviste scientifiche internazionali. È autore delle raccolte poetiche Scritti brevi (2018) e Fili d'erba (2021).Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/il-posto-delle-parole--1487855/support.IL POSTO DELLE PAROLEascoltare fa pensarehttps://ilpostodelleparole.it/

WHITEFISH CITY COUNCIL GUISEPPE CALTABIANO (G-MAN) TRT: 34:25 WORK, FAMILY, POLITICAL BACKGROUND/ABIDE BY THE OATH/PILOT/WF ”GROW UP”  

This week, Aebhric OKelly speaks with Giuseppe Mercieca, the CoROM student representative. They discuss his role as a student advocate, the importance of improvisation in medical training, and the college's future aspirations. The conversation also touches on student feedback, career pathways for paramedics, and advice for new students considering a paramedic program.TakeawaysGiuseppe is a bachelor's student preparing for his clinical placement.He aims to improve communication and support for students.High-fidelity scenarios enhance learning experiences.Improvised medical techniques are crucial in austere environments.Student feedback is essential for program development.Career opportunities exist in remote and offshore medical positions.Networking and volunteering are key to finding jobs.The college is expanding programs based on student demand.CPD courses can serve as an introduction to the program.Collaboration with other medical professionals is vital for progress.Chapters00:00 Introduction to Eye Care Course in Malta02:29 Role of Student Representative05:09 Improvised Medical Techniques07:20 Future Aspirations for the College09:27 Student Feedback and Engagement11:55 Career Pathways for Paramedics14:24 Advice for New Paramedic Students

Vita e opere più importanti di Giuseppe Berto, scrittore e sceneggiatore italiano autore di “Il cielo è rosso”, “Il brigante”, “Le opere di Dio”. Ne "Il male oscuro", la sua opera più nota, affronta il tema del complesso di Edipo e della depressione.

Kick off the Week Monday on Wake Up! Inside Track host Bruce Ash joins the show. 1st Hour:  Recap of our Giuseppe's Sunday Supper plus TUSD gets outplayed by the lefties in Iowa plus CSPAN host schools a caller about James Comey. 2nd Hour: Mike Curry, out newest Live the Dream host joins Chris and Bruce to discuss is inspiring journey from addiction to sobriety and God! 3rd hour:  Brother Joe makes his weekly appearance to talk about where the economy and politics meet!

durée : 00:27:30 - Les Midis de Culture - par : Marie Labory - Au programme du débat critique aujourd'hui : de l'Opéra, avec deux grands classiques "Aida" de Giuseppe Verdi, mise en scène par Shirin Neshat et "Les Contes d'Hoffmann" d'Offenbach, mise en scène par Lotte de Beer - réalisation : Laurence Malonda - invités : Anna Sigalevitch Journaliste et auteure; Zoé Sfez Productrice de La Série musicale sur France Culture

durée : 00:15:18 - Les Midis de Culture - par : Marie Labory - En revisitant l'Aida de Salzbourg 2022, la mise en scène de la plasticienne iranienne Shirin Neshat replace la « Marche triomphale » au cœur du drame : non plus célébration des vainqueurs, mais hommage aux vaincus, ces esclaves éthiopiens anonymes sacrifiés dans l'ombre de la gloire égyptienne. - réalisation : Laurence Malonda - invités : Anna Sigalevitch Journaliste et auteure; Zoé Sfez Productrice de La Série musicale sur France Culture

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Can the charm of classic Italian American culture withstand the pace of a modern world? Giuseppe Falanga of Brooklyn Bites takes us inside beloved Brooklyn institutions like Ferdinando's and Bari Pork Store—businesses now threatened by the “Great Extinction” of traditional Italian shops. Through personal anecdotes and community stories, Giuseppe reveals the urgency of preserving these cultural landmarks while painting a vivid picture of Brooklyn's changing landscape.   Our journey then extends beyond Brooklyn to Edmonton's Little Italy, reborn as Piazza Italia. Here we discovered rare kitchenware, indulged in authentic treats, and connected instantly with the local Italian community. These experiences sparked the creation of Brooklyn Bites, a social media brand built on passion for culinary storytelling, creative partnership, and the joy of turning personal interests into a thriving endeavor.   Together, we explore the importance of tradition, authenticity, and craftsmanship in Italian American food culture. From nostalgic meals in Brooklyn to culinary adventures abroad, our conversation underscores how storytelling and community support can keep heritage alive. With Giuseppe's infectious energy, we invite listeners to take an active role in sustaining these culinary treasures for future generations.    THEIR SOCIALS Instagram: @brooklynbitess TikTok: @brooklynbitess Facebook: BrooklynBitess X: Brooklynbites Threads: @brooklymbitess   THEIR COOKBOOK: https://found.us/creators/brooklynbitess?code=brooklynbitess&fbclid=PARlRTSAM6Yz1leHRuA2FlbQIxMQABpwE7OjQli2trmtR6389YHTZHAobTacHNxsVbSyOPpJnDrjHomR0DHlKQMcoq_aem_jysG8uf5UhHS02ua7TUUJQ

Friday is Here! Ron Arenas from Southwest Flavor is in the house! Mark Van Buren, the Movie Guy marks the passing of actor Robert Redford by counting down his favorite RR flicks. Food Friday Guest: Josh from Giuseppe's Ristorante stops by to talk Italian food and our upcoming Dining series event on Sept 28th

What happens when 25 years of corporate procurement experience meets elite business school teaching? You get Giuseppe Conti—a world-class negotiation expert with a gift for turning complex tactics into everyday skills.In this episode, Giuseppe shares his journey from growing up in a family of teachers in Southern Italy to teaching negotiation and influence at institutions like Oxford and Cambridge. His new book, Negotiation + Influence = Success, distills a career's worth of hard-earned wisdom into actionable strategies—and we break several of them down in this conversation.We cover tactical topics like:Who should make the first offer in a negotiation?How to handle procurement teams obsessed with price.How to influence internal stakeholders when you don't have authority.Giuseppe blends humility, academic insight, and battle-tested experience in one of the most practical negotiation discussions we've had on the podcast. Whether you're negotiating with a client, a boss, or your own team—this episode will sharpen your skills and change how you think about influence.Are you interested in leveling up your sales skills and staying relevant in today's AI-driven landscape? Visit www.jbarrows.com and let's Make It Happen together!Connect with John on LinkedIn: https://www.linkedin.com/in/johnbarrows/Connect with John on IG: https://www.instagram.com/johnmbarrows/Check out John's Membership: https://go.jbarrows.com/pages/individual-membership?ref=3edab1 Join John's Newsletter: https://www.jbarrows.com/newsletterConnect with Giuseppe on LinkedIn: https://www.linkedin.com/in/giuseppeconti/Check out Giuseppe's book: https://www.amazon.com/Negotiation-Influence-Success-Lessons-Corporate-ebook/dp/B0FNSKZ9F5/

The boys talk about marijuana, Juggalos, Giuseppe stops by, sampler platters, James survived a SHARK ATTACK, a greased up pole with ham at the top, and YOUR History Roads!Advertise on Dynamic Banter via gumball.fmJOIN the Patreon: patreon.com/dynamicbanterGET the MERCH: dynamicbanter.clothingSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people fail in negotiations because they don't prepare, confuse influence with persuasion, or push when they should pull—Giuseppe Conti, the world's #1 Negotiation Guru, shows you how to avoid these mistakes. Buy the book Negotiation + Influence = Success: Quick Lessons to Help You Win in Corporate Life Connect with Giuseppe Giuseppe's Website ⁠Buy the book Negotiation + Influence = Success: Quick Lessons to Help You Win in Corporate Life⁠ Contact ANI ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Request A Customized Workshop For Your Company⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Kwame Christian on LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠negotiateanything.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here to buy your copy of Finding Confidence in Conflict: How to Negotiate Anything and Live Your Best Life!⁠⁠ In this conversation with Kwame Christian, Giuseppe shares the proven strategies behind his decades of experience teaching negotiation and influence at top universities and advising Fortune 500 companies. What you'll learn in this episode: The critical mindset shift between influencing internally vs. negotiating externally Why lack of preparation is the #1 mistake people make—and how to fix it How to balance anchoring with empathy to strengthen deals and relationships The role of AI as your “smart intern” in negotiation preparation Why making the other party feel satisfied can be as valuable as the deal itself

In this episode, host Joe Crane is joined by franchise coach and author Giuseppe Grammatico. Giuseppe shares his personal journey to achieving time freedom through business ownership, which he found by leveraging the proven systems of franchising. He discusses why franchising is not a passive investment, the specific qualities that make veterans successful franchisees, and the importance of finding a business model that truly fits your lifestyle goals. Episode Resources: Giuseppe Grammatico - The Franchise Guide   About Our Guest Giuseppe Grammatico is a franchise veteran, coach, author, speaker & consultant who simplifies the process of franchising and excels at guiding his candidates to the business model that best suits their desired lifestyle. His greatest joy is helping people realize the American dream and sharing the freedom that comes from franchising. About Our Sponsors Navy Federal Credit Union   Whether you're looking to buy a new or used car or maybe you want to refinance your current car loan, Navy Federal Credit Union has great rates on auto loans and discounts for Active Duty servicemembers and Veterans. You can apply via their mobile app or online and, in most cases, get a decision in seconds. For those of you looking to refinance your current auto loan, you could get $200 cash back when you refi your loan from another lender. Find out more at navyfederal.org/auto.    At Navy Federal, our members are the mission.    Join the conversation on Facebook! Check out Veteran on the Move on Facebook to connect with our guests and other listeners. A place where you can network with other like-minded veterans who are transitioning to entrepreneurship and get updates on people, programs and resources to help you in YOUR transition to entrepreneurship.   Want to be our next guest? Send us an email at interview@veteranonthemove.com.  Did you love this episode? Leave us a 5-star rating and review!  Download Joe Crane's Top 7 Paths to Freedom or get it on your mobile device. Text VETERAN to 38470. Veteran On the Move podcast has published 500 episodes. Our listeners have the opportunity to hear in-depth interviews conducted by host Joe Crane. The podcast features people, programs, and resources to assist veterans in their transition to entrepreneurship.  As a result, Veteran On the Move has over 7,000,000 verified downloads through Stitcher Radio, SoundCloud, iTunes and RSS Feed Syndication making it one of the most popular Military Entrepreneur Shows on the Internet Today.