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3 episodes with oncogenes
2 episodes with oncogenes
3 episodes with oncogenes
2 episodes with oncogenes
2 episodes with oncogenes
Dr. Barbara Moscicki discusses the critical role of HPV in women's health, particularly its association with various cancers, including cervical cancer. She explains the dual nature of HPV as both a commensal organism and a pathogen, emphasizing the importance of understanding its oncogenic potential. The conversation also covers the significance of screening methods, such as Pap smears, in detecting precancerous changes and the complexities surrounding the treatment of different cervical intraepithelial neoplasia (CIN) stages. This conversation delves into the complexities of cancer screening methods, particularly focusing on cervical and anal cancer. Dr. Barbara Moscicki discusses the importance of understanding various screening guidelines, the role of HPV vaccination in preventing cancers, and the need for clear communication between clinicians and patients regarding these topics. The discussion highlights the evolving nature of cancer screening practices and the importance of patient education in navigating these changes.About Our Guest:Dr. Moscicki is a Pediatrician, Board Certified in Adolescent Medicine. She is the current Division Chief of Adolescent and Young Adult Medicine with clinical expertise in reproductive health care for menstrual irregularities, sexual health, and sexually transmitted diseases. Dr. Moscicki has expertise in HPV -related disease including diagnosis of cervical dysplasia and treatment. She also offers medical care for women with eating disorders.Resources & Links:This episode was supported by the Patient Centered Outcomes Research Institute (PCORI) and features the PCORI research study here: https://pubmed.ncbi.nlm.nih.gov/33632649/ ‘Effect of 2 Interventions on Cervical Cancer Screening Guideline Adherence'Chapter Codes00:00 Introduction to HPV and Women's Health03:00 Understanding HPV's Role in Cancer06:01 The Dual Nature of HPV: Commensal vs Pathogenic08:57 Oncogenes and Their Impact on Cellular Regulation12:09 The Intersection of HPV and Screening Methods14:58 Cervical Cancer Screening and Pap Smears20:30 Understanding Cancer Screening Methods23:17 Guidelines for Cervical and Anal Cancer Screening31:02 The Importance of HPV Vaccination39:35 Key Messages for Clinicians and PatientsTakeaways- Dr. Moscicki specializes in adolescent and young adult medicine.- HPV is linked to multiple cancers beyond cervical cancer.- The understanding of HPV's role in cancer has evolved significantly.- E6 and E7 proteins from HPV disrupt normal cell regulation.- CIN3 is considered a true pre-cancer that requires treatment.- Liquid cytology has improved the accuracy of Pap smears.- CIN1 is often self-resolving and does not require treatment.- CIN2 presents a diagnostic dilemma due to variability in interpretation.- Women have options regarding the management of CIN2 lesions.Connect with Us:Enjoyed this episode? Make sure to subscribe, rate, and review! Follow us on Instagram, Facebook, or Linkedin @mantacares and visit our website at mantacares.com for more episodes and updates.Listen Elsewhere: Website: https://mantacares.com/pages/podcast?srsltid=AfmBOopEP5GJ-Wd2nL-HYAInrw YouTube: https://www.youtube.com/@mantacares Spotify: https://open.spotify.com/episode/3TR1lFLtf6em5YyKtlWy2L?si=6ma-9g_w Apple: https://podcasts.apple.com/us/podcast/navigating-cervical-cancer-screening-surger Disclaimer:All content and information provided in connection with Manta Cares is solely intended for informational and educational purposes only. This content and information is not intended to be a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.This episode was supported by an award from the Patient-Centered Outcomes Research Institute.
In this episode of Conversations in Lung Cancer Research, Dr. Malinda Itchins, Dr. Annie Wong, and A/Prof Stephen Kao discuss the concept of liquid biopsy, its advantages and limitations, and its clinical applications in lung cancer treatment. They explore how liquid biopsy can provide faster diagnosis and treatment options, especially for patients who cannot undergo traditional tissue biopsies. However, they also address the challenges of sensitivity and the need for further research to integrate liquid biopsy into routine clinical practice.This episode is sponsored by: AstraZeneca Daiichi Sankyo Australia SOPHiA Genetics Thermo Fisher Scientific(00:00) Introduction and Acknowledgements(01:16) Meet the Experts(02:10) Understanding Liquid Biopsy(03:01) Advantages of Liquid Biopsy(06:21) Limitations of Liquid Biopsy(09:15) Clinical Scenarios for Liquid Biopsy(13:15) Barriers and Future Directions(19:39) Conclusion and Thank You
In this episode of Conversations in Lung Cancer Research, A/Prof Mel Moore, along with thoracic oncologists Dr. Malinda Itchins and A/Prof Surein Arulananda, delve into the characteristics, detection, and treatment of EGFR exon 20 insertion mutant non-small cell lung cancer. The podcast discusses recent advances, the efficacy of various treatments including small molecule tyrosine kinase inhibitors and monoclonal antibodies, and the potential future of targeted therapies. Special focus is given to the Phase 3 Papillon study and the drug Amivantamab, highlighting the need for next generation sequencing in clinical settings. Key challenges and questions in the field are also addressed, including the impact of co-mutations and optimal therapy sequencing.This episode is sponsored by: Johnson & Johnson(00:00) Introduction and Acknowledgements(00:48) Introducing the Experts(01:29) Understanding EGFR Exon 20 Insertion Mutations(05:04) Challenges with Current Treatments(06:30) Emerging Therapies and Clinical Trials(11:03) Papillon Study Insights(21:27) Future Directions and Unanswered Questions(29:34) Conclusion and Final Thoughts
In this TOGA podcast, we provide an overview of the treatment options for rare subtypes of oncogene driven NSCLC that are now readily identified in the MBS-reimbursed small gene panel including NTRK1, 2,3 and other rare mutations in NSCLC. The importance of testing all patients is discussed as well as what to do when resistance occurs. Associate Professor Steven Kao, Medical Oncologist from Chris O'Brien Lifehouse and Clinical Associate Professor Sydney Medical School, Faculty of Medicine and Health is joined by Professor Wendy Cooper, senior staff specialist in Tissue Pathology and Diagnostic Oncology at Royal Prince Alfred Hospital in Sydney, Anatomical Clinical Stream Lead for NSW Health Pathology, a Clinical Professor at the University of Sydney and a Conjoint Professor at the University of Western Sydney and also Professor Ben Solomon head of the lung Medical Oncology Service and a Group Leader of the Molecular Therapeutics and Biomarkers Laboratory in the Research Division at Peter MacCallum Cancer Centre as well as a Founding Board member of TOGA.
Guest: Victor Sagalovsky Victor Sagalovsky is the cofounder and CEO of Litewater Scientific, the first and only super deuterium-depleted light water, where he has dedicated himself to the research, development, and production of this rare water. Victor has researched and studied the benefits of deuterium-depleted water through his theory entitled Endogenous Radiation Damage Theory of Aging. It proposes that our biggest obstacle to longevity is the excess deuterium and other damaging isotopes on the planet and proper mitigation will radically extend our lifespans. Work With Me: Mineral Balancing HTMA Consultation: https://www.integrativethoughts.com/category/all-products My Instagram: @integrativematt My Website: Integrativethoughts.com Advertisements: Valence Nutraceuticals: Use code ITP20 for 20% off https://valencenutraceuticals.myshopify.com/ Zeolite Labs Zeocharge: Use Code ITP for 10% off https://www.zeolitelabs.com/product-page/zeocharge?ref=ITP Magnesium Breakthrough: Use Code integrativethoughts10 for 10% OFF https://bioptimizers.com/shop/products/magnesium-breakthrough Just Thrive: Use Code ITP15 for 15% off https://justthrivehealth.com/discount/ITP15 Therasage: Use Code Coffman10 for 10% off https://www.therasage.com/discount/COFFMAN10?rfsn=6763480.4aed7f&utm_source=refersion&utm_medium=affiliate&utm_campaign=6763480.4aed7f Chapters: 00:00 Introduction and Background 03:03 The Benefits of Yoga and a Healthy Lifestyle 08:01 Discovering Deuterium and Its Significance 13:11 The Challenges of Producing Deuterium-Depleted Water 21:29 The Origin and Impact of Deuterium on Earth 28:31 The Technical Process of Depleting Deuterium from Water 35:17 Target Audience and Potential Benefits 39:37 Natural Ways to Lower Deuterium Levels 44:27 Deuterium Levels in Different Foods 47:59 Testing Deuterium Levels at Home 50:09 Exploring the Potential of Deuterium Depleted Water 51:09 The Role of Deuterium in Oncogenes and Cancer 52:08 Deuterium Depleted Water as a Metabolic Intervention 53:33 The Importance of Education and Choice in Health 54:23 The Benefits of Hydrogen in Deuterium Depletion 56:17 The Significance of Water Purity in Hydrogen Machines 58:40 The Taste and Familiarity of Deuterium Depleted Water 01:02:52 Practical Applications of Deuterium Depleted Water 01:07:55 Strategies for Deuterium Depletion and Maintenance Takeaways: Deuterium is a heavy isotope of hydrogen that can impact health and longevity. Producing deuterium-depleted water is a complex and technically challenging process. Deuterium levels on Earth have increased over time, potentially affecting human physiology. Deuterium-depleted water may have benefits for those seeking to improve their health and performance. Natural methods such as fasting, a ketogenic diet, and sweating can help lower deuterium levels. Testing deuterium levels at home can provide insights into the effectiveness of deuterium-depleted water. Deuterium depleted water shows potential as a metabolic intervention and may have benefits in fighting diseases like cancer. Education and choice play a crucial role in making informed decisions about health and wellness. Hydrogen is believed to have antioxidant properties and can be beneficial in deuterium depletion. Water purity is important in hydrogen machines to ensure optimal performance and hydrogen production. Deuterium depleted water has a distinct taste and familiarity that is appealing to many individuals. Practical applications of deuterium depleted water include diluting it with regular water to achieve desired deuterium levels.
Dr Bill Nelson talks with Dr Chi Dang about his research into oncogenes and they reflect on the spirit of discovery through research that has been fostered at Johns Hopkins.
Dr. Richard Webby, faculty member at St Jude Children's Research Hospital and global expert on influenza viruses, joins Drs. Mike Brasher, Karen Waldrop, and DU staff for a look back on the 2022 Avian Flu outbreak. In this science-heavy episode we ask where it came from, is it here to stay, and what can we expect going forward? We also learn why it is showing up in mammals and what this means for our pets. Also, will mutations increase the human health risk and are waterfowl hunters at higher risk?www.ducks.org/DUPodcast
In this episode, we review the high-yield topic of Oncogenes from the Oncology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
In this episode, we review the high-yield topic of Oncogenes from the Oncology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
KSQD 5-04-2022: (Archive show) Review of genetics research focusing on genetic diseases: sickle cell, Huntingtons, fragile X syndrome, cystic fibrosis, breast cancer, Tay-Sachs, tuberculosis, Creutzfeldt–Jakob disease and prions; More genetics topics such as repetitive DNA, transposons, jumping genes, oncogenes and retroviruses
On this ID the Future, Icons of Evolution author Jonathan Wells sat down with host and fellow biologist Ray Bohlin at the August 2021 Insiders’ Briefing near Seattle to discuss some fresh discoveries into the workings of the human genome detailed in a recent article in the journal Axios, “Diving into the Genome’s Uncharted Territories.” As the article details, researchers continue to discover important functions in the noncoding regions of the human genome, once regarded by evolutionists as junk DNA. Wells and Bohlin explore the exciting new findings and some of their implications for modern evolutionary theory and intelligent design. Source
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Connie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
Dr. Harold Varmus talks to Dan Rather about his journey from literature major to scientist, and from the discovery of oncogenes to creating PLoS. Varmus reflects on his time as a researcher, as Director of the NIH, and on the importance of open communication in science. He ends by emphasizing why good science communication is important to engage more people in conversations about science.
Dr. Harold Varmus talks to Dan Rather about his journey from literature major to scientist, and from the discovery of oncogenes to creating PLoS. Varmus reflects on his time as a researcher, as Director of the NIH, and on the importance of open communication in science. He ends by emphasizing why good science communication is important to engage more people in conversations about science.
Join us for a conversation with internationally recognized Medical Oncologists and researchers, Professor Ben Solomon & Associate Professor Tom John as they discuss the increased survival benefits for patients with oncogene driven lung cancer and how novel treatments are contributing.Oncogenes discussed include EGFR & osimertinib; ALK & brigatinib, alectinib, lorlatinib; ROS1 & crizotinib, entrectinib; KRAS & sotorasib; G12C; Exon20 insertions & poziotinib, amivantamab, RET & selpercatinib, pralcetinib. Also discussed – the importance of the move beyond single gene testing to panels and NGS is important to maximise turn-around times and the efficient utilization of clinical samples.
Mechanical forces and architecture may not sound very "bio", but they are key tools of epidermal stem cells. These stem cells essentially engineer their environment by producing both the cells above them (the skin cells) and the extracellular matrix mesh (the basement membrane) that they sit on. In this episode we explore whether, when these stem cells acquire oncogenic mutations (the ones that cause cancer), do they now architect in a different way, and does this influence the development of cancer?Host Lauren Richardson and Professor Elaine Fuchs of Rockefeller University discuss her lab's recent Nature article "Mechanics of a multilayer epithelium instruct tumour architecture and function". The article investigates the differences in mechanical forces and tissue architecture in two distinct types of skin cancer: one that tends to be begin and non-invasive and one that tends to be aggressive and metastatic. The conversation covers how computational modeling played a critical role in uncovering new sources of forces and how changes in architecture influence invasive properties.
October is Breast Cancer Awareness month, worldwide. Geetha Manjunath joins host Pavan Srinath to share how breast cancer is an easily treatable illness in 2020 if caught early.Over 80,000 women in India still die annually from breast cancer, largely from late detection of cancer. Geetha discusses why breast cancer is so frequent, what factors can lead to a higher risk of cancer, how it can be detected early through regular screening, and how it can be managed.Dr Geetha Manjunath is the Founder, CEO, and CTO of NIRAMAI Health Analytix. With a background in computer science, data analytics, and machine learning, she has been working for the past 6 years in healthcare and diagnostics. Niramai has innovated on a novel, safe method for detecting early-stage breast cancer which avoids the use of X-rays as used in mammograms. Visit www.niramai.com and www.niramai.org for more information. ಬನ್ನಿ ಕೇಳಿ!ಫಾಲೋ ಮಾಡಿ. Follow the Thalé-Haraté Kannada Podcast @haratepod. Facebook: facebook.com/HaratePod/ , Twitter: twitter.com/HaratePod/ and Instagram: instagram.com/haratepod/ಈಮೇಲ್ ಕಳಿಸಿ, send us an email at haratepod@gmail.com and tell us what you think of the show. The Thale-Harate Kannada Podcast is made possible thanks to the support of The Takshashila Institution and IPSMF, the Independent Public-Spirited Media Foundation.
Discusses the 3 mechanisms through which oncogenes are formed from proto-oncogenes, and types of oncogenes with examples.
Review of genetics research focusing on genetic diseases: sickle cell, Huntington's, fragile X syndrome, cystic fibrosis, breast cancer, Tay-Sachs, tuberculosis, Creutzfeldt–Jakob disease and prions; More genetics topics such as homosexuality, repetitive DNA, transposons, jumping genes, oncogenes and retroviruses
Review of genetics research focusing on genetic diseases: sickle cell, Huntington's, fragile X syndrome, cystic fibrosis, breast cancer, Tay-Sachs, tuberculosis, Creutzfeldt–Jakob disease and prions; More genetics topics such as homosexuality, repetitive DNA, transposons, jumping genes, oncogenes and retroviruses
is a groundbreaking look at the role of water in living organisms that ultimately brings us closer to answering the riddle of the etiology of, and therapy and treatment for, cancer. When President Nixon launched the War on Cancer with the signing of the National Cancer Act of 1971 and the allocation of billions of research dollars, it was amidst a flurry of promises that a cure was within reach. The research establishment was trumpeting the discovery of oncogenes, the genes that supposedly cause cancer. As soon as we identified them and treated cancer patients accordingly, cancer would become a thing of the past. Fifty years later it’s clear that the War on Cancer has failed―despite what the cancer industry wants us to believe. New diagnoses have continued to climb; one in three people in the United States can now expect to battle cancer during their lifetime. For the majority of common cancers, the search for oncogenes has not changed the treatment: We’re still treating with the same old triad of removing (surgery), burning out (radiation), or poisoning (chemotherapy). In , Dr. Cowan argues that this failure was inevitable because the oncogene theory is incorrect―or at least incomplete―and based on a flawed concept of biology in which DNA controls our cellular function and therefore our health. Instead, Dr. Cowan tells us, the somatic mutations seen in cancer cells are the result of a cellular deterioration that has little to do with oncogenes, DNA, or even the nucleus. The root cause is metabolic dysfunction that deteriorates the structured water that forms the basis of cytoplasmic―and therefore, cellular―health. Despite mainstream medicine’s failure to bring an end to suffering or deliver on its promises, it remains illegal for physicians to prescribe anything other than the “standard of care” for their cancer patients―no matter how dangerous and ineffective that standard may be―and despite the fact that gentler, more effective, and more promising treatments exist. While Dr. Cowan acknowledges that all of these treatments need more research, is an impassioned plea from a long-time physician that these promising treatments merit our attention and research dollars and that patients have the right to information, options, and medical freedom in matters of their own life and death. Dr. Cowan, MD, is a veteran family physician who has studied and written about many subjects in medicine, including nutrition, homeopathy, anthroposophical medicine, and herbal medicine. He is the author of : A Doctor’s Quest to Understand, Treat, and Prevent Cardiovascular Disease and the new book from Chelsea Green Publishing. He is also a founding board member of the Weston A. Price Foundation, and a frequent lecturer throughout the US and Canada. He's also the same doctor I mentioned in when I talked about how your “heart is not a pump”. He also produces some of the most fantastic vegetable powders in existence, which I use every day: My previous episodes with Dr. Cowan include: - ). - - He also published the fascinating article on my website entitled: - . Dr. Cowan's other excellent books include: During our discussion, you'll discover: -Whether or not the efficacy of chemotherapy has ever been studied [7:45] President Nixon announced "War on Cancer" in 1971; promised it would be gone within 10 years Early 1990's, German statistician announces 2.9% of stage 3&4 cancer patients see improvement with chemo Early 2000's, Australian government commissions a study for all stages; Concluded that 2.3-2.4% show improvement Decreased quality of life; marginally longer life expectancy in chemo patients -Why a reduction in tumor size isn't always a good thing [12:00] Any study not involving life expectancy is called a "surrogate study" Reduction in size can result in a compromised immune system which perpetuates the need for chemo -Dr. Cowan's thoughts on the current theories upon which modern cancer treatments are based [15:30] "Oncogene" or "somatic mutation" theory came to light in 1971 Mutation in a somatic chromosome, which drives the cancer Actual results: everyone has different somatic mutations Biotech industry is based on finding problematic mutations, which are impossible to decipher After 40 years of war on cancer, over 95% of treatment has nothing to do with the oncogene theory Oncogenes are not the root cause of cancer when you get right down to it Mutations are a consequence of an improperly functioning cell, not the cause of it When you transfer the nuclei from a cancerous cell to a healthy cell, the healthy cell will not become cancerous; however, if you transfer the cytoplasm from a cancerous cell, the healthy cell will develop cancer - and his contributions to current cancer treatments [25:00] All cancers feel different (rock like) compared to other tissue Cells have a charge around them, and when two similarly charged cells come together, they keep their distance Strength of the charge determines the density of the tissue (why different organs have different textures) Halo of charges come from sodium/potassium gradient Always start with the charge: walk barefoot, swim in the ocean, sunlight, expose to heat and cold, mineral water Sodium/potassium pump is a myth "The contents of the cytoplasm are structured water" -The form of water while it's inside the cytoplasm [35:10] It's gel-like, not the forms we usually think It's a mesh that binds to the potassium in the cell, excludes the sodium, and maintains the sodium/potassium gradient Structured water forms similar to Jello ATP molecule acts as the heat that activates the gel (energy currency) Watery matrix the DNA resides in is what determines which part of the DNA will be expressed The DNA is an expression of an "idea" or a creator, and the "idea" is the water -How the integrity of the DNA and cytoplasm is damaged, thus enabling cancer to form [43:15] Cells lose charge, clump together, form a tumor Aneuploidy: the presence of an abnormal number of chromosomes in a cell Reversing the loss of charge, restoring the cell would be a more efficacious treatment for cancer than radiation, surgery, chemo, etc. Cytoplasm is akin to the birth of Jesus Christ Lourdes healing water (in France) -Gerson Therapy, Quinton and cancer treatment [50:15] "The problem with cancer is the problem of sodium/potassium" Created a juicer that extracts cytoplasm from fruits and veggies Gerson's protocol was based on increasing potassium, reducing sodium Rene Quinton's sea water (natural way of structuring water) is a mineral-rich water put through a vortex -The reason why Dr. Cowan does not treat cancer patients in his practice [57:45] -How plants and mushrooms are used to treat cancer [59:15] Mistletoe is the most used, most successful natural treatment To be injected subcutaneously Mistletoe is not currently available in the U.S. -Whether deuterium-depleted water could be an effective treatment for cancer [1:03:10] Deuterium (D2O) interferes with ability of mitochondria to generate ATP, and has different physical chemical properties from water Dr. Cowan is disappointed w/ the current state of deuterium-depleted water manufacturers "If you have cancer, or might get cancer, you should drink deuterium-depleted water." -Whether oral or IV administration is optimal for Nicotinamide adenine dinucleotide (NAD) [1:10:15] NADH is better than NAD -The value of electronic devices such as the Rife for treating cancer [1:13:30] -How melatonin is used for cancer therapy [1:15:45] -And much more... Resources from this episode: - Book: - - Study: - Quinton water from (use code GREENFIELD10) - Quinton water from Dr. Slovak's website (use code GREENFIELD for a 10% discount) - - - Melatonin (use code GREENFIELD10) - - - Bone broth recipe: Onions, carrots, greens sautéed in ghee/turmeric mixture Add Add tsp of , , - Ben's previous podcasts and episodes about cancer: - podcast with Dr. David Minkoff - podcast with Eric Remensperger - podcast with Dr. Joshua Axe Episode sponsors: -: My personal playground for new supplement formulations, Kion blends ancestral wisdom with modern science. Ben Greenfield Fitness listeners, receive a 10% discount off your entire order when you use discount code: BGF10. -: A new take on an ancient secret: Pain-soothing herbs, incredible antioxidants, and phytonutrients all in one delicious, soothing “Golden Milk” nighttime tea! Receive a 20% discount on your entire order when you use discount code: BENG20. -: Organic brands you love, for less. Your favorite organic food and products. Fast and free shipping to your doorstep. Receive 25% off your order when you use ! -: Try the shaving company that’s fixing shaving. Get a $13 value trial set that comes with everything you need for a close, comfortable shave when you go to -: Whether you’re an insurance expert or a newbie, Policygenius created a website that makes it easy for you to compare quotes, get advice, and get covered. Do you have questions, thoughts or feedback for Dr. Thomas Cowan or me? Leave your comments below and one of us will reply!
Listen to Dr. Miguel Rivera who explains why prion-like domains in mutant EWS-Fli-1 fusion proteins are instrumental in activating Ewing Sarcoma oncogenes.
Cancer Grand Rounds Lectures from the Norris Cotton Cancer Center Podcasts
Norris Cotton Cancer Center Grand Rounds -Yubao Wang, PhD Instructor, Dana-Farber Cancer Institute, Harvard Medical School
Dr Farge meets with ecancertv at EACR 2016 to discuss how mechanistic pressures from tumour cells on surrounding tissues that can lead to the spread of cancer. This is in contrast to spread of cancer through molecular signalling and cellular division, and Dr Farge describes how the physical pressure exerted by tumours can upregulate tumourigenic signalling in healthy cells. He describes the methodology behind these experiments, using magnetic liposomes to mimic tumour growth pressures.
At the interface of chemistry, biology, and medicine, Cyrille Thinnes, a DPhil student in the Schofield Group, shares his research into the next generation of anti-cancer treatments.
At the interface of chemistry, biology, and medicine, Cyrille Thinnes, a DPhil student in the Schofield Group, shares his research into the next generation of anti-cancer treatments.
We want to protect the DNA of our cell because it is our blueprint for tomorrow, and when we accumulate damage there over time that’s how we alter the genes, turn on the oncogenes (or the bad gene), and make ourselves more susceptible to a cancer. And how can we preserve this blueprint? Tune in to Eve Prang Plews, L.N.C, and her guest, Dr. Harvey, to learn more.
Runtime 39:00 Physician-scientist Timothy A. Chan discusses cancer genomics at the forefront of cancer research and how developments have allowed researchers to discover what goes wrong in cancer faster than and more thoroughly. read more
Runtime 32:00 Craig B. Thompson, President and CEO of Memorial Sloan Kettering Cancer Center, discusses new ways to think about cancer and how cancer arises in human beings. read more
We catch up with cancer research this week including evidence that cancers subvert stem cells to suppress the immune system and how covert "hit and run" viral infections may be triggering a lot more tumours than we first thought. Also, joining us from the National Cancer Research Institute conference in Liverpool, cancer biologist Bob Weinberg explains how he sees cancer becoming a controllable chronic condition within just ten years. Plus, the buzz around a new tumour-spotting ultrasound technique, how a burst of electricity to the brain boosts mathematical ability, a new trick to block the... Like this podcast? Please help us by supporting the Naked Scientists
We catch up with cancer research this week including evidence that cancers subvert stem cells to suppress the immune system and how covert "hit and run" viral infections may be triggering a lot more tumours than we first thought. Also, joining us from the National Cancer Research Institute conference in Liverpool, cancer biologist Bob Weinberg explains how he sees cancer becoming a controllable chronic condition within just ten years. Plus, the buzz around a new tumour-spotting ultrasound technique, how a burst of electricity to the brain boosts mathematical ability, a new trick to block the... Like this podcast? Please help us by supporting the Naked Scientists
Dr. Dean Felsher discusses the role of oncogenes in the pathogenesis of cancer, the concept of oncogene addiction, and the therapeutic potential of treatments that inactivate particular oncogenes. (September 15, 2008)
Runtime 33:55 Molecular biologist Prasad Jallepalli explains fundamental machinery and mechanisms of how cells divide. read more
Dr. Linda Boxer discusses genetic mutations and how they can potentially activate oncogenes. (September 21, 2007)
This is an interview on LIB Radio with Dr. Harvey Bialy, recorded June 14, 2006. Dr. Bialy discusses the difference between HIV/AIDS and STDs, why HIV is not sexually tramsitted as proven by the Padian study, and AIDS in Africa. Dr. Bialy has recently published a new book, Oncogenes, Aneuploidy, and AIDS: The Scientific Life and Times of Peter H. Duesberg, available at amazon.com.
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 tumors were examined using PCR-based fluorescent DNA technology. Amplification of the three oncogenes and the mutation of K-ras were correlated with age, tumor size, lymph node status, metastases, stage, histological types, grade, steroid hormone receptor expression (estrogen receptor, ER; progesterone receptor, PgR), family history of cancer, previous history of cancer or precursor lesions, and previous history of hormone replacement therapy. Oncogene amplification of c-erbB2 was detected in 18.9%, of c-myc in 2.7% and of int-2 in 4.2%, and K-ras mutation in 11.6%. No significant correlations could be detected between amplification of c-erbB2 and any of the other parameters. Mutation of K-ras is associated with positive expression of PgR. This might indicate that mutation and activation of K-ras are involved in the development of hormonal independence in endometrial cancer.
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