Podcasts about vpt

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Best podcasts about vpt

Latest podcast episodes about vpt

Fresh Encounter Radio Podcast
The Importance of Deliverance, Part-4

Fresh Encounter Radio Podcast

Play Episode Listen Later Nov 30, 2024 29:27


••• Achieving Total Victory, Ep 357 . ••• Bible Study Verses: Genesis 15.12-21, Joshua 1.1-5, Deuteronomy 20.16-18, Judges 1.28, Numbers 33.50-55 . ••• “Our first problem is that our attitude towards sin is more self-centred than God-centred. We are more concerned about our own "Victory" over sin than we are about the fact that our sin grieve the heart of God. We cannot tolerate failure in our struggle with sin chiefly because we are success oriented, not because we know it is offensive to God”, Jerry Bridges, 1929-?, Jerry Bridges, 1929-?, Evangelical Christian author, speaker & staff member of The Navigators. Author of over 12-books, including The Pursuit of Holiness, which has sold more than a million copies. His devotional Holiness Day By Day garnered the 2009 ECPA Christian Book Award for the inspiration & gift category, & The Discipline Of Grace received a similar award in 1995 for the Christian living category. He earned his BS in engineering at the University of Oklahoma before serving as an officer in the USN during the Korean War. He joined Christian discipleship organization The Navigators in 1955, where he served as administrative assistant to the Europe Director, office manager for headquarters, Sec.-Treasurer, & as VPt for Corp. Affairs before moving to a staff development position with the Collegiate Mission† ••• "But thanks be to God, who gives us the victory through our Lord Jesus Christ. Therefore, my beloved brethren, be steadfast, immovable, always abounding in the work of the Lord, knowing that your labor is not in vain in the Lord.”, 1 Corinthians 15:57-58, NKJV . ••• What are 5-reasons why the Hebrews never accessed the full possession of their promised land? ••• What does anger, bitterness, malice and unforgiveness to our journey here on earth? ••• What is the danger of incomplete victory? ••• What 3-life actions must a biblical christian do to flourish and enjoy the blessings God has for them? ••• What are 3-reasons why a complete victory is do important in a believer”s life? ••• Are you going to ask your small group to pray that you will be more intentional achieving total victory through the power of Holy Spirit? ••• Pastor Godwin Otuno expounds on this and much more on the exciting journey of Fresh Encounters Radio Podcast originally aired on November 30, 2024 on WNQM, Nashville Quality Ministries and WWCR World Wide Christian Radio broadcasted to all 7-continents on this big beautiful blue marble, earth, floating through space. Please be prayerful before studying The Word of God so that you will receive the most inspiration possible . ••• This Discipleship Teaching Podcast is brought to you by Christian Leadership International and all the beloved of God who believe in it's mission through prayer and support. Thank you . ••• Broadcaster's Website - https://www.lifelonganointing.com/ . •••• Exceeding Thanks to Universe Creator Christ Jesus AND Thato Moiketsi Photography, Winburg, South Africa, https://www.pexels.com/@thato-moiketsi-909645793/ . ••• † http://christian-quotes.ochristian.com/Jerry-Bridges-Quotes/ . ••• SHARING LINK: https://shows.acast.com/fresh-encounter-radio-podcast/241130-achieving-total-victory-ep357 . ••• Study Guides at - https://shows.acast.com/fresh-encounter-radio-podcast/episodes . ••• RESOURCE - https://www.soundcloud.com/thewaytogod/ . ••• RESOURCE - https://www.biblegateway.com/audio/mclean/kjv/john.1%20 . ••• FERP 241130 Episode#357 GOT 241130 Ep357 ••• The Importance of Deliverance, Part-4: Achieving Total VictorySupport this show http://supporter.acast.com/fresh-encounter-radio-podcast. Hosted on Acast. See acast.com/privacy for more information.

Geisterjäger John Sinclair
DER JOHN-SINCLAIR-PODCAST - Oktober 2024: Die Sinclair-Crew besucht das VPT

Geisterjäger John Sinclair

Play Episode Listen Later Oct 10, 2024 29:56


Lea und Michael vom Social-Media-Team haben in Wuppertal das VollPlaybackTheater besucht, um bei einer Probe für die am 11.10. beginnende John-Tour zuzusehen.Was Lea und Michael alles beim VPT erlebt haben, erfahrt ihr in dieser neusten Folge unseres Sinclair-Podcasts.Außerdem hört ihr in der Folge erstmals auch Pia-Rhona Saxe, die von nun an monatlich das aktuelle Sinclair-Hörspiel vorstellt. Hosted on Acast. See acast.com/privacy for more information.

Barbell & Bananas - Physio Podcast
072 Interview mit A. Rädlein und M. Norys - Blankoverordnung zur Physiotherapie – es geht los!

Barbell & Bananas - Physio Podcast

Play Episode Listen Later Oct 3, 2024 52:19


Physio Podcast: Neuigkeiten zur Blankoverordnung in der Physiotherapie Willkommen zu einer neuen Episode vom Physio Podcast! Heute sprechen wir über die kurz bevorstehende Einführung der Blankoverordnung in der Physiotherapie, die am 1. November 2024 in Kraft tritt. Am 02. August 2024 haben sich die vier großen Physiotherapieverbände (IFK, Physio Deutschland, VDB und VPT) mit dem GKV-Spitzenverband auf alle wesentlichen Punkte geeinigt. Die Blankoverordnung ermöglicht Physiotherapeuten mehr Verantwortung bei der Behandlung von Patienten im Bereich der Schultertherapie. Sie können nun Heilmittel auswählen, die Behandlungsfrequenz festlegen und verschiedene Therapien kombinieren. Die Blankoverordnung bringt auch neue vergütete Leistungen mit sich: Physiotherapeutische Diagnostik: 34,34 Euro vor Therapie. Bedarfsdiagnostik: 25,76 Euro während der Therapie. Mehraufwandspauschale: 55 Euro für zusätzlichen organisatorischen Aufwand. Es wird kein neues Verordnungsformular benötigt. Der Vermerk „BLANKOVERORDNUNG“ wird einfach auf dem bestehenden Muster 13 eingetragen. Die Regelungen bleiben den Heilmittel-Richtlinien und dem Vertrag nach § 125 SGB V unterworfen. Für weitere Informationen stehen die Berufsverbände zur Verfügung. Bleibt dran für mehr spannende Themen in unserem Physio Podcast! Zu Gast: Andrea Rädlein (Vorsitzende) & Markus Norys (stellv. Vorsitzender) Physio Deutschland Informationen zur Blankoverordnung Fortbildungen an der Gottfried Gutmann Akademie ⁠www.gga-hamm.de⁠ Kontakt: Ferdinand Hardinghaus  Physiotherapist, M.Sc. (cand.), Neuroathletik Master Practicioner  Instagram: ⁠⁠⁠⁠⁠⁠the.brainhealth.physio ⁠ ⁠⁠⁠⁠⁠⁠⁠Dr. Fabian Moll  Physiotherapist, OMPT, Neuroathletik Practicioner  Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Physio.Consult⁠⁠⁠⁠ ⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.fabianmoll.de⁠⁠⁠⁠⁠⁠⁠⁠⁠ Buchempfehlung die klinische Arbeit rund um den die Blankoverordnung und den Direktzugang unterstützen (Affiliate Link): ⁠⁠Differentialdiagnostik in der Physiotherapie

Monday Moms
Virginia expands online permit tool

Monday Moms

Play Episode Listen Later Jun 25, 2024 2:10


Virginia is expanding an online tool that features the majority of permit applications considered by state agencies, Gov. Glenn Youngkin announced this month. The Virginia Permit Transparency website is part of a broader effort to modernize Virginia's permitting process by making it more accessible and efficient for residents and businesses. The VPT website provides the public with a centralized platform to track the daily status and timeline of critical steps for Virginia permits. The site now allows users to search for permits by agency, application number, locality and filter results by fields such as agency, application number, locality, and more....Article LinkSupport the Show.

Actorcast
Randy Mulder: Co-founder of Village Playback Theatre | Episode 090

Actorcast

Play Episode Listen Later Oct 17, 2023 34:02


For episode 090 of Actorcast, we are joined by Randy Mulder. I've had the opportunity to train and work with Randy and I thought it essential to have him on the show to talk about playback theatre. He talk about what playback theatre is, why it's so great for community building, and how actors can benefit from awareness about playback. You can learn more about Village Playback Theatre and the NY School of Playback Theatre by visiting the following links: https://www.villageplaybacktheatre.org/ https://www.nyspt.org/ https://www.facebook.com/VillagePlaybackTheatre/ Randy Mulder is the artistic director and co-founder of Village Playback Theatre in New York City. As an applied theatre company, VPT has performed in diverse settings, from homeless shelters to Lincoln Center. Under his leadership, the company has performed throughout metro New York, many parts of the U.S., and overseas. He has led performances and workshops in schools and universities, corporations, government agencies, social services, prisons, professional conferences, psychiatric hospitals, and several shows in traditional theatres. Randy is co-director and trainer of the New York School of Playback Theatre, which attracts students from all around the world. He is a faculty member at Kansas State University School of Music, Theatre, and Dance, where he teaches drama therapy graduate students. He holds a Bachelor of Arts in music (vocal performance) and a Masters in drama therapy. Follow my work at https://patrick-mcandrew.com and @patrick.mcandrew

Spezialgelagerter Sonderpodcast
SSP Interview (XXII): Das VPT und der heimliche Hehler

Spezialgelagerter Sonderpodcast

Play Episode Listen Later Aug 22, 2023 24:52


Im März waren Tom und Olaf zu Gast beim VPT in Bremen und hatten die Gelegenheit mit Christoph Landwehr und David J. Becher ein kurzes Interview zu führen. Es geht dabei natürlich um die aktuelle Tour Die drei Fragezeichen und der heimliche Hehler in der Interpretation vom Vollplaybacktheater, welche im September fortgesetzt wird. Hier also eine kleine Einstimmung - viel Spaß!

The Bid Picture - Cybersecurity & Intelligence Analysis

In this episode, host Bidemi Ologunde spoke with Huxley Barbee, the lead organizer for BSides NYC and a Security Evangelist at runZero, a cyber asset management solution.The discussion covered various topics related to asset-centric investigations, such as the pros and cons of the different methods of conducting cyber asset inventory; operational technology (OT) scanning; and security research-based fingerprinting and incremental fingerprinting. Huxley also delved into vulnerability prioritization technology (VPT) and the utility of Shodan, a popular search engine for identifying and cataloging internet-connected devices and systems. Additionally, he mentioned some of the tools required for network access security; the stark reality of managing threat attack surfaces, and lots more. To wrap up, he shared insights into how runZero can aid organizations in securing all their network assets and devices.==============Organize your work and life, finally.Become focused, organized, and calm with Todoist. The world's #1 task manager and to-do list app.Start for free=======Receive $25 off orders of $149+ with code SWAPSRF at Snake River Farms!Whether you're a seasoned veteran or a beginner to beef, the pioneers of American Wagyu have got you covered with $25 off your order.Shop Delicious Meats Now=======Turn your Airtable or Google Sheets into modern business tools you need.Softr lets you stop waiting for developers. Build software without devs. Blazingly fast. Trusted by 100,000+ teams worldwide.Start building now.=======Sesame Care - Doctor appointments as low as $19.Find the best price for the highest quality physicians. Book an appointment in minutes.Get Started=======Compliantly hire anyone, anywhere, in 5 minutes with Deel.Deel is your one-stop shop for hiring, paying, and managing your remote team. We stay on top of local labor laws across the world to ensure compliance and mitigate risk so that you don't have to.Get Started=======Shut The Box Game.Dating back to 12th century France, sailors cherished playing Shut The Box Game. In modern times whether you're camping with friends or relaxing with family, you'll have endless fun with this easy-to-learn game! Buy 2, Get 1 Free, plus free shipping within the United States.Get Started=======Support the show

How Do You Say That?!
Jonathan Tilley: The one with the Dastardly Tech Script!

How Do You Say That?!

Play Episode Listen Later Apr 21, 2023 33:22


In this week's "How Do You Say That?!" Jonathan Tilley, voiceover and personal brand strategist, joins Sam and Mark to talk about promoting your vo business properly, why tech script is sometimes the worst, and in the wildcards Sam channels Sweden and Jonathan becomes horrifying!Our VO question this week is all about how important it is for voiceovers to be present and engaged on social media.We'd love you to join in and send us your version of one of the reads in today's show – just pop it onto an mp3 and send it to podcast@britishvoiceover.co.ukScript 1If it's a mainly adult audience - or students over 18 - then you may want to be a little more suggestive with the script and jokes. There could be topical contemporary references for your audience - local characters, news headlines, politicians, celebrities and so on. Rude jokes are essential and, depending on your audience, you may choose to include risqué language (though innuendo, double entendres and the threat of a swear word are often more effective than the real thing). Of course - you need to be clear in your advertising that this isn't for kids - for example “Sinderella” so that you don't have complaints at the end of the evening!Script 2With the filter frequency, you suppress interference on counter inputs F, J and, if applicable, W. With compressed VPTs, a frequency of 129 kHz is cyclically reset by default - meaning that signal changes shorter than 4 µs are suppressed.The VPT_Definitive_Exchanger Technology object guides you in the configuration, commissioning and diagnosis of the position reflection and measurement features for the RB position output technology module in conjunction with VPT definitive exchangers - not to mention, the SP2_RAM Technology object enables you to easily configure ram counter-control of the SP 8x73VFRQ/5J RP analog input module for operation with an exchanger module and use it as the master program.——————- Listen to all of our podcasts here——————–About our guest: Jonathan Tilley was born in Boston, Massachusetts. As a musical theatre performer, he starred in the productions of Cats, 42nd Street and Mamma Mia! At 30 he transitioned into the voiceover industry and has thousands of corporate narrations, e-learning modules, and commercials under his belt for some very high-end blue chip clients. In 2010 Jonathan began coaching fellow creatives on the business side of being a creative freelancer turning his knowledge into online courses like League Of List Builders. As a personal brand strategist he helps creative people shine online and share their talent with the world. Jonathan loves white wine spritzers on hot summer days and French bulldogs. Jonathan's Website @jonathantilleydotcom on Instagram Mark's demos & contact details: https://linktr.ee/britishvoiceovermarkSam's demos & contact details: https://linktr.ee/samanthaboffin

We Go Boldly Podcast
EPISODE 106: Unlocking what is holding us back with David Echevarria

We Go Boldly Podcast

Play Episode Listen Later Mar 1, 2023 60:58


This season on We Go Boldly we will walk through what holds us back from living our best lives and doing all the things we dream about doing. Today we are broadening our own horizons and talking to an incredible guest and new friend to the show. Welcome David Echevarria! David is the Founder and CEO of VPT.FIT.   While in college, along with 3 friends David started a Youtube channel sharing our workouts, offering advice and guidance to others. That channel grew to over 150,000 subscribers. He graduated with a Bachelors of Engineering from Stevens Institute of Technology in 2014. His focus of study was in body mechanics.After college, he moved on from Youtube and worked as an engineer for 3.5 years in various industries. While employed, I always had side projects that I was working on with varying levels of success. My wife and I partnered up in 2016 and grew our wellness practice to where we were able to quit our jobs in 2019. They still run this today. The pandemic hit shortly after and put us through many ups and downs. During that time is when they started VPT.FIT. It was initially a free service to help people who were stuck in their homes during lockdown, but it was a success and has grown since then!Today, VPT.FIT is The Online Gym That FITS YOU! They provide custom workouts built to each individual, and we use technology and innovation to provide efficiency and innovation.We are so excited to have David join us today! Check him out.Did you enjoy this episode? We would love to hear your thoughts. Head to Apple Podcasts and then rate, review, and subscribe. This way you will get notified once a new episode goes live.CONNECT WITH RIELLY AND TOVAHInstagram: https://www.instagram.com/goboldlytogether/Website: goboldlythepodcast.comFacebook: https://www.facebook.com/Go-Boldly-Together-105942584706928LinkedIn: https://linkedin.com/company/go-boldly-initiativeYouTube: http://bit.ly/boldlyyoutubePinterest: https://www.pinterest.com/GoBoldlyTogether/_saved/Twitter: https://twitter.com/goboldlypodcastPatreon: https://www.patreon.com/wegoboldly

PaperPlayer biorxiv neuroscience
Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Oct 21, 2022


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.20.513074v1?rss=1 Authors: Hadaya, L., Dimitrakopoulou, K., Vanes, L. D., Kanel, D., Fenn-Moltu, S., Gale-Grant, O., Counsell, S., Edwards, A. D., Saqi, M., Batalle, D., Nosarti, C. Abstract: Very preterm birth (VPT; less than or equal to 32 weeks gestation) is associated with altered brain development and cognitive and behavioral difficulties across the lifespan. However, heterogeneity in outcomes among individuals born VPT makes it challenging to identify those most vulnerable to neurodevelopmental sequelae. Here, we aimed to stratify VPT children into distinct behavioral subgroups and explore between-subgroup differences in neonatal brain structure and function. 198 VPT children (98 females) previously enrolled in the Evaluation of Preterm Imaging study (EudraCT 2009-011602-42) underwent Magnetic Resonance Imaging at term-equivalent age and neuropsychological assessments at 4-7 years. Using an integrative clustering approach, we combined neonatal socio-demographic, clinical factors and childhood socio-emotional and executive function outcomes, to identify distinct subgroups of children based on their similarity profiles in a multidimensional space. We characterized resultant subgroups using domain-specific outcomes (temperament, psychopathology, IQ and cognitively stimulating home environment) and explored between-subgroup differences in neonatal brain volumes (voxel-wise Tensor-Based-Morphometry), functional connectivity (voxel-wise degree centrality) and structural connectivity (Tract-Based-Spatial-Statistics). Results showed two- and three-cluster data-driven solutions. The two-cluster solution comprised a "resilient" subgroup (lower psychopathology and higher IQ, executive function and socio-emotional outcomes) and an "at-risk" subgroup (poorer behavioral and cognitive outcomes). The three-cluster solution showed an additional third "intermediate" subgroup displaying behavioral and cognitive outcomes intermediate between the resilient and at-risk subgroups. The resilient subgroup had the most cognitively stimulating home environment and the at-risk subgroup showed the highest neonatal clinical risk, while the intermediate subgroup showed the lowest clinical but the highest socio-demographic risk. Compared to the intermediate subgroup, the resilient subgroup displayed larger neonatal insular and orbitofrontal volumes and stronger orbitofrontal functional connectivity, while the at-risk group showed widespread white matter microstructural alterations. These findings suggest that risk stratification following VPT birth is feasible and could be used translationally to guide personalized interventions aimed at promoting children's resilience. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Astro arXiv | all categories
Perturbation theory with dispersion and higher cumulants: non-linear regime

Astro arXiv | all categories

Play Episode Listen Later Oct 17, 2022 0:54


Perturbation theory with dispersion and higher cumulants: non-linear regime by Mathias Garny et al. on Monday 17 October We present non-linear solutions of Vlasov Perturbation Theory (VPT), describing gravitational clustering of collisionless dark matter with dispersion and higher cumulants induced by orbit crossing. We show that VPT can be cast into a form that is formally analogous to standard perturbation theory (SPT), but including additional perturbation variables, non-linear interactions, and a more complex propagation. VPT non-linear kernels have a crucial decoupling property: for fixed total momentum, the kernels becomes strongly suppressed when any of the individual momenta cross the dispersion scale into the non-linear regime. This screening of UV modes allows us to compute non-linear corrections to power spectra even for cosmologies with very blue power-law input spectra, for which SPT diverges. We compare predictions for the density and velocity divergence power spectra as well as the bispectrum at one-loop order to N-body results in a scaling universe with spectral indices $-1leq n_sleq +2$. We find a good agreement up to the non-linear scale for all cases, with a reach that increases with the spectral index $n_s$. We discuss the generation of vorticity as well as vector and tensor modes of the velocity dispersion, showing that neglecting vorticity when including dispersion would lead to a violation of momentum conservation. We verify momentum conservation when including vorticity, and compute the vorticity power spectrum at two-loop order, necessary to recover the correct large-scale limit with slope $n_w=2$. Comparing to our N-body measurements confirms the cross-over from $k^4$ to $k^2$ scaling on large scales. Our results provide a proof-of-principle that perturbative techniques for dark matter clustering can be systematically improved based on the known underlying collisionless dynamics. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2210.08089v1

Astro arXiv | all categories
Perturbation theory with dispersion and higher cumulants: framework and linear theory

Astro arXiv | all categories

Play Episode Listen Later Oct 17, 2022 1:08


Perturbation theory with dispersion and higher cumulants: framework and linear theory by Mathias Garny et al. on Monday 17 October The standard perturbation theory (SPT) approach to gravitational clustering is based on a fluid approximation of the underlying Vlasov-Poisson dynamics, taking only the zeroth and first cumulant of the phase-space distribution function into account (density and velocity fields). This assumption breaks down when dark matter particle orbits cross and leads to well-known problems, e.g. an anomalously large backreaction of small-scale modes onto larger scales that compromises predictivity. We extend SPT by incorporating second and higher cumulants generated by orbit crossing. For collisionless matter, their equations of motion are completely fixed by the Vlasov-Poisson system, and thus we refer to this approach as Vlasov Perturbation Theory (VPT). Even cumulants develop a background value, and they enter the hierarchy of coupled equations for the fluctuations. The background values are in turn sourced by power spectra of the fluctuations. The latter can be brought into a form that is formally analogous to SPT, but with an extended set of variables and linear as well as non-linear terms, that we derive explicitly. In this paper, we focus on linear solutions, which are far richer than in SPT, showing that modes that cross the dispersion scale set by the second cumulant are highly suppressed. We derive stability conditions on the background values of even cumulants from the requirement that exponential instabilities be absent. We also compute the expected magnitude of averaged higher cumulants for various halo models and show that they satisfy the stability conditions. Finally, we derive self-consistent solutions of perturbations and background values for a scaling universe and study the convergence of the cumulant expansion. The VPT framework provides a conceptually straightforward and deterministic extension of SPT that accounts for the decoupling of small-scale modes. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2210.08088v1

The Nonlinear Library
LW - AI Timelines via Cumulative Optimization Power: Less Long, More Short by jacob cannell

The Nonlinear Library

Play Episode Listen Later Oct 6, 2022 30:44


Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: AI Timelines via Cumulative Optimization Power: Less Long, More Short, published by jacob cannell on October 6, 2022 on LessWrong. TLDR: We can best predict the future by using simple models which best postdict the past (ala Bayes/Solomonoff). A simple model based on net training compute postdicts the relative performance of successful biological and artificial neural networks. Extrapolation of this model into the future leads to short AI timelines: ~75% chance of AGI by 2032. Cumulative Optimization Power[1]: a Simple Model of Intelligence A simple generalized scaling model predicts the emergence of capabilities in trained ANNs(Artificial Neural Nets) and BNNs(Biological Neural Nets): perf ~= P = CT For sufficiently flexible and efficient NN architectures and learning algorithms, the relative intelligence and capabilities of the best systems are simply proportional to net training compute or intra-lifetime cumulative optimization power P, where P = CT (compute ops/cycle training cycles), assuming efficient allocation of (equivalent uncompressed) model capacity bits N roughly proportional to data size bits D. Intelligence Rankings Imagine ordering some large list of successful BNNs(brains or brain modules) by intelligence (using some committee of experts), and from that deriving a relative intelligence score for each BNN. Obviously such a scoring will be noisy in its least significant bits: is a bottlenose dolphin more intelligent than an american crow? But the most significant bits are fairly clear: C. Elegans is less intelligent than Homo Sapiens. Now imagine performing the same tedious ranking process for various successful ANNs. Here the task is more challenging because ANNs tend to be far more specialized, but the general ordering is still clear: char-RNN is less intelligent than GPT-3. We could then naturally combine the two lists, and make more fine-grained comparisons by including specialized sub-modules of BNNs (vision, linguistic processing, etc). The initial theory is that P - intra-lifetime cumulative optimization power (net training compute) - is a very simple model which explains a large amount of the entropy/variance in a rank order intelligence measure: much more so than any other simple proposed candidates (at least that I'm aware of). Since P follow a predictable temporal trajectory due to Moore's Law style technological progress, we can then extrapolate the trends to predict the arrival of AGI. This simple initial theory has a few potential flaws/objections, which we will then address. Initial Exemplars I've semi-randomly chosen 15 exemplars for more detailed analysis: 8 BNNs, and 9 ANNs. Here are the 8 BNNs (6 whole brains and 2 sub-systems) in randomized order: Honey Bee Human Raven Human Linguistic Cortex Cat C. Elegans Lizard Owl Monkey Visual Cortex The ranking of the 6 full brains in intelligence is rather obvious and likely uncontroversial. Ranking all 8 BNNs in terms of P (net training compute) is still fairly obvious. Here are the 9 ANNs, also initially in randomized order: AlphaGo: First ANN to achieve human pro-level play in Go Deepspeech 2: ANN speech transcription system VPT: Diamond-level minecraft play Alexnet: Early CNN imagenet milestone, subhuman performance 6-L MNIST MLP: Early CNN milestone on MNIST, human level Chinchilla: A 'Foundation' Large Language Model GPT-3: A 'Foundation' Large Language Model DQN Atari: First strong ANN for Atari, human level on some games VIT L/14@336px: OpenAI CLIP 'Foundation' Large Vision Model Most of these systems are specialists in non-overlapping domains, such that direct performance comparison is mostly meaningless, but the ranking of the 3 vision systems should be rather obvious based on the descriptions. The DQN Atari and VPT agents are somewhat comparable to animal brains. How would you ran...

The Nonlinear Library: LessWrong
LW - AI Timelines via Cumulative Optimization Power: Less Long, More Short by jacob cannell

The Nonlinear Library: LessWrong

Play Episode Listen Later Oct 6, 2022 30:44


Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: AI Timelines via Cumulative Optimization Power: Less Long, More Short, published by jacob cannell on October 6, 2022 on LessWrong. TLDR: We can best predict the future by using simple models which best postdict the past (ala Bayes/Solomonoff). A simple model based on net training compute postdicts the relative performance of successful biological and artificial neural networks. Extrapolation of this model into the future leads to short AI timelines: ~75% chance of AGI by 2032. Cumulative Optimization Power[1]: a Simple Model of Intelligence A simple generalized scaling model predicts the emergence of capabilities in trained ANNs(Artificial Neural Nets) and BNNs(Biological Neural Nets): perf ~= P = CT For sufficiently flexible and efficient NN architectures and learning algorithms, the relative intelligence and capabilities of the best systems are simply proportional to net training compute or intra-lifetime cumulative optimization power P, where P = CT (compute ops/cycle training cycles), assuming efficient allocation of (equivalent uncompressed) model capacity bits N roughly proportional to data size bits D. Intelligence Rankings Imagine ordering some large list of successful BNNs(brains or brain modules) by intelligence (using some committee of experts), and from that deriving a relative intelligence score for each BNN. Obviously such a scoring will be noisy in its least significant bits: is a bottlenose dolphin more intelligent than an american crow? But the most significant bits are fairly clear: C. Elegans is less intelligent than Homo Sapiens. Now imagine performing the same tedious ranking process for various successful ANNs. Here the task is more challenging because ANNs tend to be far more specialized, but the general ordering is still clear: char-RNN is less intelligent than GPT-3. We could then naturally combine the two lists, and make more fine-grained comparisons by including specialized sub-modules of BNNs (vision, linguistic processing, etc). The initial theory is that P - intra-lifetime cumulative optimization power (net training compute) - is a very simple model which explains a large amount of the entropy/variance in a rank order intelligence measure: much more so than any other simple proposed candidates (at least that I'm aware of). Since P follow a predictable temporal trajectory due to Moore's Law style technological progress, we can then extrapolate the trends to predict the arrival of AGI. This simple initial theory has a few potential flaws/objections, which we will then address. Initial Exemplars I've semi-randomly chosen 15 exemplars for more detailed analysis: 8 BNNs, and 9 ANNs. Here are the 8 BNNs (6 whole brains and 2 sub-systems) in randomized order: Honey Bee Human Raven Human Linguistic Cortex Cat C. Elegans Lizard Owl Monkey Visual Cortex The ranking of the 6 full brains in intelligence is rather obvious and likely uncontroversial. Ranking all 8 BNNs in terms of P (net training compute) is still fairly obvious. Here are the 9 ANNs, also initially in randomized order: AlphaGo: First ANN to achieve human pro-level play in Go Deepspeech 2: ANN speech transcription system VPT: Diamond-level minecraft play Alexnet: Early CNN imagenet milestone, subhuman performance 6-L MNIST MLP: Early CNN milestone on MNIST, human level Chinchilla: A 'Foundation' Large Language Model GPT-3: A 'Foundation' Large Language Model DQN Atari: First strong ANN for Atari, human level on some games VIT L/14@336px: OpenAI CLIP 'Foundation' Large Vision Model Most of these systems are specialists in non-overlapping domains, such that direct performance comparison is mostly meaningless, but the ranking of the 3 vision systems should be rather obvious based on the descriptions. The DQN Atari and VPT agents are somewhat comparable to animal brains. How would you ran...

JE Notícias
Prazo para pagamento do Adicional ao IMI termina hoje | O Jornal Económico

JE Notícias

Play Episode Listen Later Sep 30, 2022 1:00


Pago durante o mês de setembro, o AIMI incide sobre imóveis habitacionais e terrenos para construção, sendo o seu valor calculado pela Autoridade Tributária e Aduaneira (AT) com base no valor patrimonial tributário (VPT) dos prédios que constam das matrizes em 1 de janeiro do ano a que o imposto diz respeito.

Noticias de Tecnología Express
Google alerta sobre expansión del spyware Hermit – NTX

Noticias de Tecnología Express

Play Episode Listen Later Jun 27, 2022 8:24


Entrenan inteligencia artificial con Minecraft, el spyware Hermit sigue atacando y venden NFTs con selfies de gallo, gallina y pollo.Puedes apoyar la realización de este programa con una suscripción. Más información por acáNoticias:-Twitter anunció que su botón para alternar subtítulos para su reproductor de video ya está disponible para todos los usuarios.-OpenAI entrenó a una inteligencia artificial para jugar Minecraft usando videos de internet con el método de aprendizaje por imitación semi-supervisada conocido como VPT o Video PreTraining.disponible para todos.-Gallos y gallinas venden selfies como NFTs (con ayuda de humanos, desde luego).-Walmart anunció la semana pasada que desarrolló una manera para cambiar entre proveedores de servidores en la nube y sus propios servidores.-Google lanzó alertas sobre una nueva campaña de Spyware que han usado actores maliciosos para robar información sensible de dispositivos con iOS y Android en Italia y Kazakhstan.Discusión: Hermit y sus capacidades expandibles. See acast.com/privacy for privacy and opt-out information. Become a member at https://plus.acast.com/s/noticias-de-tecnologia-express.

The Nonlinear Library
LW - [Link] OpenAI: Learning to Play Minecraft with Video PreTraining (VPT) by Aryeh Englander

The Nonlinear Library

Play Episode Listen Later Jun 23, 2022 1:24


Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: [Link] OpenAI: Learning to Play Minecraft with Video PreTraining (VPT), published by Aryeh Englander on June 23, 2022 on LessWrong. We trained a neural network to play Minecraft by Video PreTraining (VPT) on a massive unlabeled video dataset of human Minecraft play, while using only a small amount of labeled contractor data. With fine-tuning, our model can learn to craft diamond tools, a task that usually takes proficient humans over 20 minutes (24,000 actions). Our model uses the native human interface of keypresses and mouse movements, making it quite general, and represents a step towards general computer-using agents. And from the Conclusion: VPT paves the path toward allowing agents to learn to act by watching the vast numbers of videos on the internet. Compared to generative video modeling or contrastive methods that would only yield representational priors, VPT offers the exciting possibility of directly learning large scale behavioral priors in more domains than just language. While we only experiment in Minecraft, the game is very open-ended and the native human interface (mouse and keyboard) is very generic, so we believe our results bode well for other similar domains, e.g. computer usage. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org.

The Nonlinear Library: LessWrong
LW - [Link] OpenAI: Learning to Play Minecraft with Video PreTraining (VPT) by Aryeh Englander

The Nonlinear Library: LessWrong

Play Episode Listen Later Jun 23, 2022 1:24


Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: [Link] OpenAI: Learning to Play Minecraft with Video PreTraining (VPT), published by Aryeh Englander on June 23, 2022 on LessWrong. We trained a neural network to play Minecraft by Video PreTraining (VPT) on a massive unlabeled video dataset of human Minecraft play, while using only a small amount of labeled contractor data. With fine-tuning, our model can learn to craft diamond tools, a task that usually takes proficient humans over 20 minutes (24,000 actions). Our model uses the native human interface of keypresses and mouse movements, making it quite general, and represents a step towards general computer-using agents. And from the Conclusion: VPT paves the path toward allowing agents to learn to act by watching the vast numbers of videos on the internet. Compared to generative video modeling or contrastive methods that would only yield representational priors, VPT offers the exciting possibility of directly learning large scale behavioral priors in more domains than just language. While we only experiment in Minecraft, the game is very open-ended and the native human interface (mouse and keyboard) is very generic, so we believe our results bode well for other similar domains, e.g. computer usage. Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org.

RRHH para todos
227. Valoraciones de puestos de trabajo, con María José Oyanedel

RRHH para todos

Play Episode Listen Later May 16, 2022 28:50


¡Siempre Puedes Practicar Surf: Episodio 227! Hoy tenemos con nosotros a una de nuestras compañeras de GHC: ¡María José Oyanedel! Mari forma parte del equipo de Desarrollo Organizacional, y es toda una experta en ayudar a las empresas con sus Valoraciones de Puestos de Trabajo. Además, es la encargada de impartir nuestro próximo Taller Online: […]

Az Utazási Podcast
#39 „Lakóautózás összekovácsolja a családot” // Rákóczi Feri

Az Utazási Podcast

Play Episode Listen Later Dec 20, 2021 89:59


Rákóczi Ferit szerintem nem kell senkinek bemutatnom, azt viszont kevesen tudják róla, hogy Feri és családja imádnak lakóautózni. De mit szeretnek ennyire benne? Milyen elvárásokkal érdemes neki vágni? Mikre kell figyelni? És a legfontosabb, hogy milyen élményeket lehet szerezni?Szó lesz az indulásról, gyereknevelésről, a családi háttérről és persze nem hagyhatjuk ki az olyan helyi kajákat sem, mint például a bottarga.

IN THE CLINIC with Rob
Why You Are Making Your Back Pain WORSE and How Rob Almost Didn't Get Married! | Episode 14

IN THE CLINIC with Rob

Play Episode Listen Later Dec 10, 2021 68:23


Hey Team! In this Episode, Rob gets going with a funny story of how he almost ruined his chances of marrying his wife, Mandy. He gives an update on his son's tonsil surgery and his daughter's obsession with basketball. Free will or No Free Will is hotly debated and how it can be directly applied to improve your life. Rob touches on the upcoming BIG BASH event for our VPT members and gives tangible ways to reduce your holiday stress. Back pain is a big topic as he discusses three reasons you will not be able to nix your back pain, and he has a great sit-down interview with Randy Hartzell, PT. Randy is a back and neck specialist who is also an Oklahoma native! Rob and Randy have too much fun as they discuss the Men of Sumner PT Calendar ;) Stay Tuned as this is an action-packed episode. Want to jump ahead? 2:10 How Rob almost ruined his chances of getting married! 13:33 What is the Big Bash? 15:38 Why Free Will doesn't exist 32:47 Top 6 Ways to Reduce Holiday Stress 40:39 What are the top 3 Reasons Your Back Pain Won't Quit! 51:15 Special Guest Interview with Randy Hartzell, PT Thank you Team, for listening. ********Get the FREE TIPS REPORT: "How to Put an End to Back Pain and Stiffness - Without Taking Painkillers, Without Risking Surgery and Without Having to Wait to See the GP!" INSTANTLY!!! —->>> Go to https://sumnerpt.com/backpain and click on the report.******** You are the absolute best part of our show! Keep Moving! Want to learn more about grieving and dealing with a loss of a loved one? Please email rob@sumnerpt.com and add to the subject: Continue with more great topics at sumnerpt.com/podcasts —-> Subscribe to our Youtube Channel: https://www.youtube.com/channel/UC3veuXHmSUWxFqbbj0tP7Gw —-> Subscribe to Apple Podcasts: https://podcasts.apple.com/us/podcast/in-the-clinic-with-rob/id1577005898?itsct=podcast_box_link&itscg=30200&ls=1

LifeTime Training Podcast
Episode #86 - Will Mahoney - Why Virtual Training at LifeTime

LifeTime Training Podcast

Play Episode Listen Later Nov 2, 2021 33:35


Join 22 year vet and National Program Manager for Virtual Training at LifeTime and Jason Stella discuss...What led him to LifeTime and why he took this position?How he feels Virtual Training is going to help the industry and help Fitness Professionals in the future?What the biggest differences between the Best Virtual Trainers vs. In Person Trainers?How does virtual training work at LifeTime?What is the Digital Membership? The benefits of working at LifeTime as a virtual trainer vs. doing it on their own?What Virtual trainers should expect to make?How does someone apply to become a VPT at LifeTimeMore about Will....22 years vet in the health and digital fitness industries with luxury brands like Equinox, 24 hour and Xponential fitness. After a few years of conversations, we finally got him over to LifeTime Where he is National Program Manager for Virtual Training.LinkedIn.com/in/willmaloney

The Gary Null Show
The Gary Null Show - 10.11.21

The Gary Null Show

Play Episode Listen Later Oct 11, 2021 58:37


Can low temperature-aged garlic enhance exercise performance? Korea Univesity & National Institute of Agricultural Sciences (South Korea), October 8, 2021 Scientists from South Korea's National Institute of Agricultural Sciences and Korea University looked at aged garlic to see whether it could help reduce fatigue. To do this, they conducted a study on mice fed with a special low-temperature-aged garlic (LTAG). Their findings were published in the Journal of Medicinal Food. Testing the fatigue-fighting effects of low temperature-aged garlic The researchers chose to use LTAG because it lacked the pungent odor and spicy flavor of regular garlic, making it easier to use for animal testing. To create the LTAG, the researchers stored garlic in a sealed container, aging at 60 C for 60 days. The resulting LTAG was then peeled and pulverized, before being added to 200 milliliters of 70 percent ethanol (EtOH), which was then subjected to ultrasonic extraction three times. This 70 percent EtOH and LTAG extract was then concentrated under a vacuum at 45 C and then lyophilized to create a dry LTAG residue. After the creation of the LTAG, the researchers then separated mice into six groups. The first group was given a low dose of LTAG extract; the second was fed a high dose of LTAG extract; the third was given a low dose of garlic extract; and the fourth was given a high dose of garlic extract. The fifth and sixth groups consisted of normal mice that were given phosphate-buffered saline (PBS) instead of garlic. One of these control groups was made to exercise while the other group was not. The mice in the five groups were forced to run on a treadmill for four weeks. With each passing week, the amount of exercise the mice would have to do on the treadmills would increase. This was done by increasing both the speed that the mice had to run, and the amount of time they had to spend running. (Related: How to alleviate fatigue with herbal medicine.) After 28 days of treatment, five mice from each group were subjected to a final, exhaustive treadmill test. This test increased the treadmill speed from 15 meters per minute (m/min) to 40 m/min every 3 minutes. During this test, the running time was monitored until each mouse failed to follow the increase in speed on three consecutive occasions and lag occurred. At this point, the mouse's total running time was recorded. The effect of the LTAG on the levels of glucose, lactate dehydrogenase (LDH), free fatty acid (FFA) and lactate in the mice's blood. Following the final exercise, the mice were killed and blood samples were collected from them. In addition, the mice's gastrocnemius muscles were also isolated and frozen in liquid nitrogen for testing. LTAG treated mice demonstrated less fatigue Following the exhaustive running tests, the researchers found that the mice treated with LTAG extract were able to run for much longer than the control mice. Meanwhile, looking at the blood tests, they noted that the mice treated with LTAG extract exhibited lower levels of glucose, LDH, FFA and lactate. More importantly, the LTAG treated mice had increased amounts of glycogen and creatine kinase (CK) in their muscles. Glycogen storage is an important source of energy during exercise. It serves a central role in maintaining the body's glucose homeostasis by supplementing blood glucose. Because of this, glycogen is seen as an accurate marker for fatigue, with increased glycogel levels closely associated with improved endurance and anti-fatigue effects. CK, on the other hand, is known to be an accurate indicator of muscle damage. During muscle degeneration, muscle cells are dissolved and their contents enter the bloodstream. As a result, when muscle damage occurs, muscle CK comes out into the blood. As such, fatigue tends to lead to lower muscle CK levels and higher blood CK levels. Higher levels of glycogen and muscle CK in the LTAG treated mice indicated that they experienced less fatigue than the other groups. Based on these findings, the researchers believe that LTAG has potential for use as an anti-fatigue agent.       Mindfulness meditation helps preterm-born adolescents University of Geneva (Switzerland), October 7, 2021 Adolescents born prematurely present a high risk of developing executive, behavioral and socio-emotional difficulties. Now, researchers from Geneva University Hospitals (HUG) and the University of Geneva (UNIGE) have revealed that practicing mindfulness may help improve these various skills. The study, published in the journal Scientific Reports, suggests using mindfulness as a means of clinical intervention with adolescents, whether prematurely born or not. Several studies have already shown that very preterm (VPT) children and adolescents are at higher risk of exhibiting cognitive and socio-emotional problems that may persist into adulthood. To help them overcome the difficulties they face, researchers from the HUG and UNIGE have set up an intervention based on mindfulness, a technique known to have beneficial effects in these areas. Mindfulness consists in training the mind to focus on the present moment, concentrating on physical sensations, on breathing, on the weight of one's body, and even on one's feelings and thoughts, completely judgment-free. The mindfulness-based interventions generally take place in a group with an instructor along with invitations to practice individually at home. To accurately assess the effects of mindfulness, a randomized controlled trial was performed with young adolescents aged 10 to 14, born before 32 weeks gestational weeks. Scientists quickly found that mindfulness improves the regulation of cognitive, social and emotional functions, in other worlds, our brain's ability to interact with our environment. Indeed, it increases the ability to focus on the present—on thoughts, emotions and physical sensations, with curiosity and non-judgment. Thanks to this practice, adolescents improve their executive functions, i.e. the mental processes that enable us to control our behavior to successfully achieve a goal. As a result, young people find it easier to focus, manage and regulate their behavior and emotions in everyday life. For eight weeks, the young teens spent an hour and a half each week with two mindfulness instructors. They were further encouraged to practice mindfulness daily at home. Parents were also involved in this study. They were asked to observe their child's executive functions, for example the ability to regulate their emotions and attentional control, their relationships with others and their behavior. The adolescents also underwent a series of computerized tasks to assess their reactions to events. A comparison of their test results with a control group that did not practice mindfulness shows a positive impact of the intervention on the adolescents' everyday life and on their ability to react to new events. "Each teenager is unique, with their own strenghts and difficulties. Through their involvement in this study, our volunteers have contributed to show that mindfulness can help many young people to feel better, to refocus and to face the world, whether they were born preterm born or not," agree Dr. Russia Hà-Vinh Leuchter, a consultant in the Division of Development and Growth, Department of Paediatrics, Gynaecology and Obstetrics at Geneva University Hospitals, and Dr. Vanessa Siffredi, a researcher at the Child Development Laboratory at the Department of Paediatrics, Gynaecology and Obstetrics at the UNIGE Faculty of Medicine, two of the authors of this work. "However, while the practice of meditation can be a useful resource, it is important to be accompanied by well-trained instructors", they specify. The adolescents who took part in the program are now between 14 and 18 years. Scientists are currently evaluating the long-term effects of mindfulness-based intervention on their daily attention and stress. Furthermore, to validate their clinical data with neurobiological measurements, researchers are currently studying the effects of mindfulness on the brain using magnetic resonance imaging (MRI).   Iron deficiency in middle age is linked with higher risk of developing heart disease University Heart and Vasculature Centre Hamburg (Germany) 6 October 2021 Approximately 10% of new coronary heart disease cases occurring within a decade of middle age could be avoided by preventing iron deficiency, suggests a study published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).1 “This was an observational study and we cannot conclude that iron deficiency causes heart disease,” said study author Dr. Benedikt Schrage of the University Heart and Vasculature Centre Hamburg, Germany. “However, evidence is growing that there is a link and these findings provide the basis for further research to confirm the results.” Previous studies have shown that in patients with cardiovascular diseases such as heart failure, iron deficiency was linked to worse outcomes including hospitalisations and death. Treatment with intravenous iron improved symptoms, functional capacity, and quality of life in patients with heart failure and iron deficiency enrolled in the FAIR-HF trial.2 Based on these results, the FAIR-HF 2 trial is investigating the impact of intravenous iron supplementation on the risk of death in patients with heart failure. The current study aimed to examine whether the association between iron deficiency and outcomes was also observed in the general population. The study included 12,164 individuals from three European population-based cohorts. The median age was 59 years and 55% were women. During the baseline study visit, cardiovascular risk factors and comorbidities such as smoking, obesity, diabetes and cholesterol were assessed via a thorough clinical assessment including blood samples. Participants were classified as iron deficient or not according to two definitions: 1) absolute iron deficiency, which only includes stored iron (ferritin); and 2) functional iron deficiency, which includes iron in storage (ferritin) and iron in circulation for use by the body (transferrin). Dr. Schrage explained: “Absolute iron deficiency is the traditional way of assessing iron status but it misses circulating iron. The functional definition is more accurate as it includes both measures and picks up those with sufficient stores but not enough in circulation for the body to work properly.” Participants were followed up for incident coronary heart disease and stroke, death due to cardiovascular disease, and all-cause death. The researchers analysed the association between iron deficiency and incident coronary heart disease, stroke, cardiovascular mortality, and all-cause mortality after adjustments for age, sex, smoking, cholesterol, blood pressure, diabetes, body mass index, and inflammation. Participants with a history of coronary heart disease or stroke at baseline were excluded from the incident disease analyses. At baseline, 60% of participants had absolute iron deficiency and 64% had functional iron deficiency. During a median follow-up of 13.3 years there were 2,212 (18.2%) deaths. Of these, a total of 573 individuals (4.7%) died from a cardiovascular cause. Incidence coronary heart disease and stroke were diagnosed in 1,033 (8.5%) and 766 (6.3%) participants, respectively. Functional iron deficiency was associated with a 24% higher risk of coronary heart disease, 26% raised risk of cardiovascular mortality, and 12% increased risk of all-cause mortality compared with no functional iron deficiency. Absolute iron deficiency was associated with a 20% raised risk of coronary heart disease compared with no absolute iron deficiency, but was not linked with mortality. There were no associations between iron status and incident stroke. The researchers calculated the population attributable fraction, which estimates the proportion of events in 10 years that would have been avoided if all individuals had the risk of those without iron deficiency at baseline. The models were adjusted for age, sex, smoking, cholesterol, blood pressure, diabetes, body mass index, and inflammation. Within a 10-year period, 5.4% of all deaths, 11.7% of cardiovascular deaths, and 10.7% of new coronary heart disease diagnoses were attributable to functional iron deficiency. “This analysis suggests that if iron deficiency had been absent at baseline, about 5% of deaths, 12% of cardiovascular deaths, and 11% of new coronary heart disease diagnoses would not have occurred in the following decade,” said Dr. Schrage. “The study showed that iron deficiency was highly prevalent in this middle-aged population, with nearly two-thirds having functional iron deficiency,” said Dr. Schrage. “These individuals were more likely to develop heart disease and were also more likely to die during the next 13 years.” Dr. Schrage noted that future studies should examine these associations in younger and non-European cohorts. He said: “If the relationships are confirmed, the next step would be a randomised trial investigating the effect of treating iron deficiency in the general population.”     Consumption of a bioactive compound from Neem plant could significantly suppress development of prostate cancer National University of Singapore, September 29, 2021   Oral administration of nimbolide, over 12 weeks shows reduction of prostate tumor size by up to 70 per cent and decrease in tumor metastasis by up to 50 per cent   A team of international researchers led by Associate Professor Gautam Sethi from the Department of Pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore (NUS) has found that nimbolide, a bioactive terpenoid compound derived from Azadirachta indica or more commonly known as the neem plant, could reduce the size of prostate tumor by up to 70 per cent and suppress its spread or metastasis by half.   Prostate cancer is one of the most commonly diagnosed cancers worldwide. However, currently available therapies for metastatic prostate cancer are only marginally effective. Hence, there is a need for more novel treatment alternatives and options.   "Although the diverse anti-cancer effects of nimbolide have been reported in different cancer types, its potential effects on prostate cancer initiation and progression have not been demonstrated in scientific studies. In this research, we have demonstrated that nimbolide can inhibit tumor cell viability -- a cellular process that directly affects the ability of a cell to proliferate, grow, divide, or repair damaged cell components -- and induce programmed cell death in prostate cancer cells," said Assoc Prof Sethi.   Nimbolide: promising effects on prostate cancer   Cell invasion and migration are key steps during tumor metastasis. The NUS-led study revealed that nimbolide can significantly suppress cell invasion and migration of prostate cancer cells, suggesting its ability to reduce tumor metastasis. The researchers observed that upon the 12 weeks of administering nimbolide, the size of prostate cancer tumor was reduced by as much as 70 per cent and its metastasis decreased by about 50 per cent, without exhibiting any significant adverse effects.   "This is possible because a direct target of nimbolide in prostate cancer is glutathione reductase, an enzyme which is responsible for maintaining the antioxidant system that regulates the STAT3 gene in the body. The activation of the STAT3 gene has been reported to contribute to prostate tumor growth and metastasis," explained Assoc Prof Sethi. "We have found that nimbolide can substantially inhibit STAT3 activation and thereby abrogating the growth and metastasis of prostate tumor," he added.   The findings of the study were published in the April 2016 issue of the scientific journal Antioxidants & Redox Signaling. This work was carried out in collaboration with Professor Goh Boon Cher of Cancer Science Institute of Singapore at NUS, Professor Hui Kam Man of National Cancer Centre Singapore and Professor Ahn Kwang Seok of Kyung Hee University.   The neem plant belongs to the mahogany tree family that is originally native to India and the Indian sub-continent. It has been part of traditional Asian medicine for centuries and is typically used in Indian Ayurvedic medicine. Today, neem leaves and bark have been incorporated into many personal care products such as soaps, toothpaste, skincare and even dietary supplements.       Review looks at the efficacy of acupuncture in treating insulin resistance Guangzhou University of Chinese Medicine (China), October 8, 2021 In their report, researcherss from Guangzhou University of Chinese Medicine in China explored the role of acupuncture in treating insulin resistance. The study was published in the journal Complementary Therapies in Clinical Practice. Earlier studies have reported the effectiveness of acupuncture in treating insulin resistance and related conditions. The review looked at acupuncture and its effects on clinical outcomes. The researchers searched the following databases for randomized controlled trials involving insulin resistance patients treated with acupuncture: Cochrane Central Register of Controlled Trials Embase Medline (via OVID) China National Knowledge Infrastructure (CNKI) Wan Fang and China Science and Technology Journal Database (VIP) The studies show that homeostasis model assessment of insulin resistance significantly decreased with acupuncture treatment. Other significant decreases include fasting blood glucose, postprandial blood glucose and fasting insulin. Acupuncture increased insulin sensitivity with very few adverse effects. In sum, acupuncture is a safe and effective alternative treatment for insulin resistance.     Blueberries may improve attention in children following double-blind trial University of Reading (UK), October 10, 2021  Primary school children could show better attention by consuming flavonoid-rich blueberries, following a study conducted by the University of Reading. In a paper published in Food & Function, a group of 7-10 year olds who consumed a drink containing wild blueberries or a matched placebo and were tested on their speed and accuracy in completing an executive task function on a computer. The double blind trial found that the children who consumed the flavonoid-rich blueberry drink had 9% quicker reaction times on the test without any sacrifice of accuracy. In particular, the effect was more noticeable as the tests got harder. Professor Claire Williams, a neuroscience professor at the University of Reading said: "This is the first time that we have seen the positive impact that flavonoids can have on the executive function of children. We designed this double blind trial especially to test how flavonoids would impact on attention in young people as it's an area of cognitive performance that hasn't been measured before. "We used wild blueberries as they are rich in flavonoids, which are compounds found naturally in foods such as fruits and their juices, vegetables and tea. They have been associated with a range of health benefits including antioxidant and anti-inflammatory effects, and our latest findings continue to show that there is a beneficial cognitive effect of consuming fruit and vegetables, tea, coffee and even dark chocolate which all contain flavonoids." The children were then asked to pay attention to an array of arrows shown on a PC screen and press a key corresponding to the direction that the central arrow was facing. The task was repeated over a number of trials, where cognitive demand was manipulated by varying how quickly the arrows appeared, whether there were additional arrows appearing either side of the central arrow, and whether the flanking arrows were pointing in the same/different direction as the central arrow. Previous Reading research has shown that consuming wild blueberries can improve mood in children and young people, simple memory recall in primary school children, and that other flavonoid rich drinks such as orange juice, can also improve memory and concentration. The Wild Blueberry Association of North America provided a freeze-dried powder made from wild blueberries which was used in the study but did not provide any additional financial support and did not play a role in the design of the study. Wild blueberries are grown and harvested in North America, and are smaller than regular blueberries, and are higher in flavonoids compared to regular varieties. The double-blind trial used a flavonoid-rich wild blueberry drink, with a matched placebo contained 8.9g of fructose, 7.99g of glucose and 4 mg of vitamin C matching the levels of nutrients found in the blueberry drink. The amount of fructose is akin to levels found in a standard pear. This was an executive function task- requiring participants to pay attention to stimuli appearing on screen and responding correctly. The task was a simple one- responding to the direction of an arrow in the middle of a screen (by pressing left/right arrow key) but we then varied how quickly the stimuli appeared, whether there was additional arrows appearing either side of the stimuli and whether those flanking arrows were pointing in the same/different direction as they direction you had to respond. There are 6 main classes of flavonoids: Anthocyanins – found in berry fruits such as the blueberries used in this study and also in red wine. Flavonols - found in onions, leeks, and broccoli Flavones - found in parsley and celery, Isoflavones - found in soy and soy products, Flavanones - found in citrus fruit and tomatoes Flavanols—found in green tea, red wine, and chocolate     Nocebo effect: Does a drug's high price tag cause its own side effects? University Medical Center Hamburg (Germany), October 5, 2021  Pricey drugs may make people more vulnerable to perceiving side effects, a new study suggests—and the phenomenon is not just "in their heads." The study delved into the so-called "nocebo effect." It's the negative version of the well-known placebo effect, where people feel better after receiving a therapy because they expected good things. With the nocebo effect, patients' worries over treatment side effects make them feel sick. In this study, researchers found that people were more likely to report painful side effects from a fake drug when told it was expensive. But it wasn't just something people were "making up." Using brain imaging, the researchers traced the phenomenon to specific activity patterns in the brain and spine. "These findings are a strong argument against the perception of placebo and nocebo effects as being only 'fake' effects—created purely by imagination or delusions of the patient," said lead researcher Alexandra Tinnermann. She is with the University Medical Center Hamburg-Eppendorf, in Germany. Dr. Luana Colloca, a researcher at the University of Maryland in Baltimore, agreed. "This is not merely a reflection of people's biases," said Colloca, who wrote an editorial published with the study. "Expectations do modulate symptoms and patients' responses to treatment," she said. For the study, Tinnermann's team recruited 49 healthy volunteers and randomly assigned them to test one of two itch-relieving "medical creams." In reality, both creams were identical and contained no active ingredients. However, people in both groups were told that the products could have the side effect of making the skin more sensitive to pain. There was only one apparent difference between the two phony creams: One came in fancy packing with a high price tag; the other was cheap. After participants applied the creams to their forearms, the researchers had them undergo a standard test that measured their tolerance for heat-induced pain. It turned out that people who'd used the expensive cream were more sensitive to pain during the tests. On average, their pain rating hovered around a 15—within the "mild" pain range—whereas people using the cheap cream barely registered any discomfort. It's likely, Tinnermann said, that people expect a pricey medication to be potent—which could also make them expect more side effects. Colloca agreed. We are all "vulnerable" to such outside influences, she said, be it a drug's price or how it's given (by IV versus mouth, for instance). However, we are not just imagining those placebo or nocebo effects, both researchers noted. Using functional MRI brain scans, Tinnermann's team found specific patterns of nervous system activity in people who had a nocebo response to the pricey cream. That included a change in "communication" between certain brain structures and the spinal cord, Tinnermann said. According to Colloca, research like this can have practical uses. Doctors could, for instance, inform patients that drug prices or other factors can sway their expectations about a treatment's benefits and risks—and that, in turn, can influence whether they feel better or develop side effects. There is, however, no research into whether that kind of knowledge helps prevent patients from the nocebo effect, Tinnermann said. But, she added, health professionals can be aware that patients' expectations "play a huge role in medicine"—and be mindful of how they talk about a medication and its possible side effects. It's an important matter, Colloca said, because the nocebo effect can cause people to stop taking needed medications. Colloca pointed to the example of cholesterol-lowering statins. The potential for those medications to cause muscle pain has been widely reported. And one recent study found evidence that this knowledge can make statin users more likely to report muscle pain side effects. Other research, Colloca said, has shown that when people stop taking their statins, their risk of heart attack and stroke rises.

#StartDisrupting
From Blacksburg to Mars with Dan Sable Ph.D. Founder & CEO, VPT

#StartDisrupting

Play Episode Listen Later Mar 22, 2021 19:07


Join us for episode 3 as Brett takes you on a journey with Dan to learn how their products are powering exploration and discovery, the importance of mentoring, and challenges to being an entrepreneur. Learn more about VPT at http://www.vptpower.com​.

Lietuvos diena
Lietuvos diena. Kokią kryptį amerikiečiai pasirinko rinkdami prezidentą?

Lietuvos diena

Play Episode Listen Later Nov 4, 2020 54:35


JAV prezidentas Donaldas Trampas ir jo varžovas demokratas Džo Baidenas kovoja dėl Baltųjų rūmų. Pagrindinis dėmesys sutelktas į balsų skaičiavimą keliose valstijose, kur abiejų kandidatų šansai yra apylygiai.Kokia JAV prezidento rinkimų reikšmė Lietuvos verslui?Vyriausybė spręs dėl trijų savaičių karantino įvedimo visoje šalyje, siekiant suvaldyti koronaviruso plitimą. Kaip sprendžiama medikų trūkumo problema ir užtikrinamas prekybos centrų darbuotojų saugumas?Prezidentas žada apsispręsti dėl Viešųjų pirkimų tarnybos (VPT) vadovo paskyrimo. Pagrindiniais reikalavimais būsimam vadovui įvardijami principingumas ir atsparumas politinei įtakai.VDU steigia paramos fondą ir priims dar papildomai 50 studentų iš Baltarusijos.Kompozitorių Faustą Latėną prisimena bičiuliai ir jo kūrybos tyrinėtojai.Ved. Paulius Šironas

Geo Travel
VPT Circuitos Europa Geo Radio

Geo Travel

Play Episode Listen Later Jun 25, 2020 94:55


Estupenda platica con nuestros amigos de VPT donde nos explica los productos y beneficios de este producto Europeo, programa de nuestra estación de radio

Bodybuilding and Physique Podcast
Virtual PT'ing, setting up a home gym and training during lockdown

Bodybuilding and Physique Podcast

Play Episode Listen Later Apr 1, 2020 47:13


Join me today with repeat guest Marc Thrasivoulou as we discuss a range of coronavirus/COVID19 related topics 01:40 How has life changed as a PT during the lockdown 07:45 What does a VPT session look like 10:33 Will you ever go back to traditional 1-2-1 PT'ing 13:45 Marc' take on this from a spiritual angle 15:51 Benefits of a home gym 24:10 Basic home gym requirements 24:30 The importance of progressive overload even in a home gym 27:40 Discussing recent Mike Israetel home gym equipment controversy 29:43 Back to the advanced home gym set up 38:22 Basic equipment for the general population

Built on Hope
Episode 080 - Gettings Reps to Prep for Regional

Built on Hope

Play Episode Listen Later Dec 16, 2018 73:03


BATTLE REPORTS(S) AND STRATEGY DISCUSSION!We held our regionals prep tournament today at our local store in Salt Lake City, Utah. Ten players showed up, two of whom were running Spectre, and we had four rounds of swiss. It was a great tournament.I was able to talk with some of the participants in the tournament. Listeners will recognize Scott, Sam Sweeten, and Robert, and I led off with a discussion with Josh Weight on his Jedi list that he built to take on Spectre. Scott was running VPT, Sam was running Spectre, and Robert was running Scum Pointers. Each of our discussions in couched in the context of matchups; for example, Scott talks about why he thinks that he needs to start running Spectre over Vader.Thank you all and Happy Holidays!

Zion's Finest
Episode 080 - Gettings Reps to Prep for Regional

Zion's Finest

Play Episode Listen Later Dec 15, 2018 73:03


BATTLE REPORTS(S) AND STRATEGY DISCUSSION! We held our regionals prep tournament today at our local store in Salt Lake City, Utah. Ten players showed up, two of whom were running Spectre, and we had four rounds of swiss. It was a great tournament. I was able to talk with some of the participants in the tournament. Listeners will recognize Scott, Sam Sweeten, and Robert, and I led off with a discussion with Josh Weight on his Jedi list that he built to take on Spectre. Scott was running VPT, Sam was running Spectre, and Robert was running Scum Pointers. Each of our discussions in couched in the context of matchups; for example, Scott talks about why he thinks that he needs to start running Spectre over Vader. Thank you all and Happy Holidays!

Built on Hope
Episode 076 - Home Court Advantage

Built on Hope

Play Episode Listen Later Nov 12, 2018 62:39


STRATEGY DISCUSSION.Scott and I played back-to-back games on Lothal Wastes (Fluctuations). Scott threw VPT vs. Spectre in game one and I took the Box into action vs. Spectre in game two. Spectre won both games. Scott gives his initial impressions of the map (I have played it several times previously), and we talk about general strategies both for and against Spectre players.Let me know if you get word about a regional!Send and email to zionsfinestia@gmail.com.Support us on Patreon at patreon.com/zionsfinest!

Zion's Finest
Episode 076 - Home Court Advantage

Zion's Finest

Play Episode Listen Later Nov 11, 2018 62:39


STRATEGY DISCUSSION. Scott and I played back-to-back games on Lothal Wastes (Fluctuations). Scott threw VPT vs. Spectre in game one and I took the Box into action vs. Spectre in game two. Spectre won both games. Scott gives his initial impressions of the map (I have played it several times previously), and we talk about general strategies both for and against Spectre players. Let me know if you get word about a regional! Send and email to zionsfinestia@gmail.com. Support us on Patreon at patreon.com/zionsfinest!

Bay Seasoning
Bay Seasoning Episode 11 “Our Not So Private Parts"

Bay Seasoning

Play Episode Listen Later Apr 2, 2018 57:06


In preparation for Passover, Tory and Philip make vodka grape juice and meyer lemon cocktails, because Tory thinks red grape juice is the same as Manischewitz. The meat of this episode [awful word choice I know] is about Tory’s VPT (vagina physical therapy). Thanks to this subset of the medical profession, that nobody talks about, women are able to reclaim their vaginas by increasing blood flow, stimulating nerves, reducing leakage and reconnecting with their vagina. Tory’s life post childbirth has never been the same and she wants all women out there to know there’s help out there! Our resident hypochondriac, Philip, talks about the perfect bridal shower gift (kegel ball sets), before going into details about his fear of having pinworms in his bum and potentially testicular cancer. Thankfully this is what husbands are for, checking to see if you have creatures living in your bum and to talk you off a ledge! Additional topics: Vagina wands Passover seder Finger puppets Vaginal confusion Kegels

LRT Aktualijų studija
LRT aktualijų studija 2018-03-07 11:05

LRT Aktualijų studija

Play Episode Listen Later Mar 7, 2018 50:32


Santaros klinikose kilęs viešųjų pirkimų skandalas tik dar kartą parodo, kad problemų šioje srityje apstu. Viešaisiais pirkimais piktnaudžiaujančios institucijos ir jų vadovai, sveikatos, statybų, informacinių technologijų ir kiti sektoriai reikalauja apsivalymo ir protingesnio lėšų panaudojimo. Per viešuosius pirkimus kasmet išleidžiama per 4 mlrd. eurų, apie 40 proc. viso valstybės biudžeto, dažnai permokant 20–30, net 50 proc. daugiau nei rinkos kaina. O pinigų trūksta viskam – mokytojų atlyginimams, investicijoms.Apie tai kartu su VPT vadove Diana Vilyte, Valstybės kontrolės valdymo departamento direktoriaus pavaduotoja Jūra Ivonaityte ir DELFI.lt verslo korespondentu Edgaru Savicku.

LRT Aktualijų studija
LRT aktualijų studija 2018-03-07 11:05

LRT Aktualijų studija

Play Episode Listen Later Mar 7, 2018 50:32


Santaros klinikose kilęs viešųjų pirkimų skandalas tik dar kartą parodo, kad problemų šioje srityje apstu. Viešaisiais pirkimais piktnaudžiaujančios institucijos ir jų vadovai, sveikatos, statybų, informacinių technologijų ir kiti sektoriai reikalauja apsivalymo ir protingesnio lėšų panaudojimo. Per viešuosius pirkimus kasmet išleidžiama per 4 mlrd. eurų, apie 40 proc. viso valstybės biudžeto, dažnai permokant 20–30, net 50 proc. daugiau nei rinkos kaina. O pinigų trūksta viskam – mokytojų atlyginimams, investicijoms.Apie tai kartu su VPT vadove Diana Vilyte, Valstybės kontrolės valdymo departamento direktoriaus pavaduotoja Jūra Ivonaityte ir DELFI.lt verslo korespondentu Edgaru Savicku.

60 minučių
60 minučių 2017-06-29 17:00

60 minučių

Play Episode Listen Later Jun 29, 2017 57:50


Lietuvoje visą dieną siaučia škvalas, kokios žalos jis pridarė?Seimas patvirtino universitetų optimizavimo planą – jų liks mažiau nei pusė. Interviu su lietuvių mokslininku, atsidūrusiu ant NATURE žurnalo viršelio.Aukšto rango Vatikano kardinolas apkaltintas seksualiniu priekabiavimu prie vaikų.Interviu su VPT direktore Diana Vilyte, išrinkta geriausia valstybės tarnautoja.

VPodcasT
Das Vollplaybacktheater präsentiert die drei ???

VPodcasT

Play Episode Listen Later Oct 1, 2008


Ab dem 01. November 2008 ist das VPT mit dem neuen Stück "Die drei ??? und die bedrohte Ranch" auf Tour! Das solltet Ihr auf keinen Fall verpassen...

VPodcasT
VollPodcastTheater 04 - Der Betriebsausflug

VPodcasT

Play Episode Listen Later Oct 15, 2007


Zur Aufrechterhaltung des super Betriebsklimas hat man sich beim VPT kurz vor der Herbst-/ Wintertour zu einem Betriebsausflug ins Phantasialand aufgemacht. Doch leider verlief der Ausflug nicht ganz so, wie geplant… Infos und Termine zur aktuellen Tour findet Ihr unter www.vollplaybacktheater.de

VPodcasT
VollPodcastTheater 01

VPodcasT

Play Episode Listen Later Mar 20, 2007


Die erste Folge - Ab sofort steht VPT nicht mehr nur für 'Vollplaybacktheater' sondern auch für 'VideoPodcasT'! Das Vollplaybacktheater gewährt Blicke hinter die Kulissen. Und weil man dafür erst einmal wissen muß, wo die Kulissen überhaupt stehen, führt Doktor Thomas exklusiv durch die Zentrale vom Vollplaybacktheater. Herzlich Willkommen!