Podcasts about Cutcliffe

We have a mashup episode today, with several experts diving into the critical role of the microbiomes in our bodies. In this episode, Dr. Colleen Cutcliffe explains why fiber is essential for gut health and the challenges of cultivating anaerobic probiotics outside the body. Dr. Elisa Song discusses the impact of antibiotics on children's gut and mental health. Dr. William Li highlights how plant-based foods nourish gut bacteria, metabolism, and mental well-being. Dr. Nathan Bryan dives into the role of the oral microbiome in nitric oxide production, and Dr. Vincent Pedre explains how glyphosate contributes to leaky gut and health issues and examines how alcohol and environmental toxins impact weight management.  Join us for today's in-depth exploration of how our microbiomes impact digestion, health, and overall well-being. Ep. 346 Gut Health: Unveiling the Science of the Microbiome with Dr. Colleen Cutcliffe [00:02:18]- [00:25:22] Dr. Cutcliffe highlights the importance of dietary fiber for supporting gut microbes, metabolism, and overall health and explains the challenges of growing anaerobic probiotics like Akkermansia outside the body.  Ep. 360 Raising Resilient Kids: Insights from Holistic Pediatrician Dr. Elisa Song [00:12:17] - [00:24:28] Dr. Song highlights the often overlooked effects of antibiotics on gut and mental health, emphasizing the importance of educating preteens, teens, and young adults about how their daily choices impact their microbiome, brain function, and long-term health.  [31:30]- [00:43:01] Why it is essential to understand how antibiotics and birth control impact the gut microbiomes of children and the importance of nurturing their resilience and restoring balance in their microbiomes over time. Ep. 354 Metabolism Myths Debunked: Weight Gain Insights with Dr. William Li [00:01:46] - [00:24:29] Dr. William William Li clarifies how bioactive compounds in plant-based foods feed gut bacteria, benefiting metabolism and mental well-being. He also highlights the importance of a healthy diet for gut health and explains how colonoscopy prep temporarily alters the gut microbiome. Ep. 379 Understanding Nitric Oxide and Its Impact on Our Health with Dr. Nathan Bryan [00:13:46]- [00:21:51] Dr. Nathan Bryan explores the crucial role of the oral microbiome in nitric oxide production and how mouthwash or fluoride products can disrupt that process, leading to higher blood pressure and reduced cardiovascular protection. [00:35:04]- [00:37:17] How, even though antibiotics and antiseptic mouthwash can disrupt the oral microbiome, the microbial communities can recover when given proper care and nutrition. Ep. 296 Secrets of Gut Microbiome and Glyphosate with Vincent Pedre [1:56-27:39] Dr. Vincent Pedre highlights how glyphosate disrupts the gut microbiome due to its mineral-binding and antimicrobial properties, leading to imbalances, leaky gut, and numerous health issues. [48:00- 1:02:15] The role alcohol, gut bacteria, and environmental exposure play in weight management and gut health, and how certain bacteria may lead to increased caloric extraction from food. Connect with Cynthia Thurlow   Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com

Dive into the world of entrepreneurship and personal growth with Dr. Colleen Cutcliffe, CEO and Co-Founder of Pendulum. In this episode, we explore the challenges and triumphs of building a groundbreaking health company from the ground up. Dr. Cutcliffe, Cofounder & CEO of Pendulum Therapeutics, , shares: The mindset required to persevere and achieve long-term entrepreneurial success How to build and maintain a strong team in the face of adversity Strategies for handling rejection and maintaining focus A personal story of overcoming academic failure and finding success The importance of faith and perspective in entrepreneurship Learn valuable lessons on resilience, teamwork, and personal growth from a scientist-turned-entrepreneur who's changing the health industry. Get my weekly newsletter - Adaptation Book Erik for your next event Start AIM7 for Free Promo code: BLUEPRINT for 20% off of all membership first orders → Pendulum Life Follow Dr. Cutcliffe & Pendulum on Instagram Quotable moments: "I decided a long time ago that health was how I wanted to make my mark." - Dr. Colleen Cutcliffe "To be a successful entrepreneur, you have to be a little bit of a psychopath. You have to be able to block out a bunch of the stuff that's coming your way." - Dr. Colleen Cutcliffe "It's about the hope and faith that you can make something. And it's about the team of people that you work with every day." - Dr. Colleen Cutcliffe "I'm not the best in class. I wasn't the person getting straight A's at Johns Hopkins, but I understand what people are looking for." - Dr. Colleen Cutcliffe ABOUT THE BLUEPRINT PODCAST: The BluePrint Podcast is for busy professionals and Household CEOs who care deeply about their families, career, and health. Host Dr. Erik Korem distills cutting edge-science, leadership, and life skills into simple tactics optimized for your busy lifestyle and goals.   Dr. Korem interviews scientists, coaches, elite athletes, entrepreneurs, entertainers, and exceptional people to discuss science and practical skills you can implement to become the most healthy, resilient, and impactful version of yourself. On a mission to equip people to pursue audacious goals, thrive in uncertainty, and live a healthy and fulfilled life, Dr. Erik Korem is a High-Performance pioneer. He introduced sports science and athlete-tracking technologies to collegiate and professional (NFL) football over a decade ago. He has worked with the National Football League, Power-5 NCAA programs, gold-medal Olympians, Nike, and the United States Department of Defense. Erik is an expert in sleep and stress resilience. He is the Founder and CEO of AIM7, a health and fitness app that unlocks the power of wearables by providing you with daily personalized recommendations to enhance your mind, body, and recovery. SUPPORT & CONNECT Instagram - https://www.instagram.com/erikkorem/ Twitter - https://twitter.com/ErikKorem LinkedIn - https://www.linkedin.com/in/erik-korem-phd-19991734/ Facebook - https://www.facebook.com/erikkorem Website - https://www.erikkorem.com/ Newsletter - http://link.aim7.com/adaptation-newsletterSee omnystudio.com/listener for privacy information.

This weeks guest is Dr. Colleen Cutcliffe. Dr. Colleen Cutcliffe is a researcher and a thinker with persistence. Throughout history, these are the human qualities that lead people to develop amazing products and lead projects for the world to benefit from. Her story is one of discovery, passion and caring. Dr. Cutcliffe holds a Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and a B.A. in Biochemistry from Wellesley College. Her scientific background is complemented by her experience in managing both research and operations teams in the biotech sector. Before founding Pendulum Therapeutics, she held senior positions at Pacific Biosciences and Elan Pharmaceuticals, where she was instrumental in developing various technological platforms. She is the co-founder and CEO of Pendulum Therapeutics, a biotechnology company focused on developing innovative solutions to improve gut health through microbiome-based interventions. With over 20 years of experience in the biotechnology industry, Dr. Cutcliffe has become a recognized leader in microbiome science, applying her expertise to bridge the gap between cutting-edge research and practical, consumer-facing health solutions. At Pendulum Therapeutics, Dr. Cutcliffe has led the development of novel probiotic formulations specifically designed to address metabolic diseases like type 2 diabetes. Her work has been pivotal in the growing recognition of the microbiome's role in human health, pushing forward the concept of targeted probiotics as a potential therapeutic option. Under her leadership, Pendulum Therapeutics has gained recognition for its scientific rigor and innovative approaches to personalized nutrition. Today, we discuss the story of her discovery and the fact that her work is the beginning of a hopeful wave of change for humans through gut microbiome manipulation. Dr. Cutcliffe helps us understand the basics of the microbiome, what helps it stay balanced and conversely, what upsets it. How does it support our metabolism and health in general. The main thrust of her work comes into the spotlight with Akkermansia mucinophilia, a keystone species for positive health. Please Enjoy my conversation with Dr. Cutcliffe, Dr. M

Unlock the secrets of your gut microbiome with Dr. Colleen Cutcliffe, CEO and Co-Founder of Pendulum. In this eye-opening episode, we explore the hidden world of bacteria living inside us and their profound impact on our health. Dr. Cutcliffe, a biochemistry expert with over 25 years of experience, reveals: How your microbiome changes throughout your life The surprising link between gut bacteria and mood Why diversity is key for a healthy microbiome Why akkermansia muciniphila is a crucial strain for gut lining health and GLP-1 production The truth about antibiotics and your gut health Groundbreaking research on probiotics for diabetes management Learn how nurturing your microbiome could be the key to better health, metabolism, and even blood sugar control. Don't miss this fascinating dive into the cutting-edge science of gut health. Get my weekly newsletter - Adaptation Book Erik for your next event Start AIM7 for Free Promo code: BLUEPRINT for 20% off of all membership first orders → Pendulum Life Follow Dr. Cutcliffe & Pendulum on Instagram Quotable moments: "We've co-evolved with these microbes. They play a super important role in health as well as disease." - Dr. Colleen Cutcliffe "Your gut is actually tied to every single biological system from your metabolism to your brain, to your immune system." - Dr. Colleen Cutcliffe "Diet is one of the most powerful ways that you can influence your microbiome." - Dr. Colleen Cutcliffe "We showed that in people with type two diabetes, we were able to lower A1C by 0.6 points and lower blood glucose spikes by 33%." - Dr. Colleen Cutcliffe "The microbiome is all the bacteria, viruses, and fungi that live in and on us." - Colleen Cutcliffe "Your gut bacteria help metabolize the food you eat, impacting your overall health." - Colleen Cutcliffe "Diversity in your diet is key to a healthy and resilient microbiome." - Colleen Cutcliffe "Antibiotics can decimate your microbiome, but a post-antibiotic regimen can help recover it." - Colleen Cutcliffe "Acromansiomucinophila plays a crucial role in maintaining your gut lining and stimulating GLP-1 hormone production." - Colleen Cutcliffe   ABOUT THE BLUEPRINT PODCAST: The BluePrint Podcast is for busy professionals and Household CEOs who care deeply about their families, career, and health. Host Dr. Erik Korem distills cutting edge-science, leadership, and life skills into simple tactics optimized for your busy lifestyle and goals.   Dr. Korem interviews scientists, coaches, elite athletes, entrepreneurs, entertainers, and exceptional people to discuss science and practical skills you can implement to become the most healthy, resilient, and impactful version of yourself. On a mission to equip people to pursue audacious goals, thrive in uncertainty, and live a healthy and fulfilled life, Dr. Erik Korem is a High-Performance pioneer. He introduced sports science and athlete-tracking technologies to collegiate and professional (NFL) football over a decade ago. He has worked with the National Football League, Power-5 NCAA programs, gold-medal Olympians, Nike, and the United States Department of Defense. Erik is an expert in sleep and stress resilience. He is the Founder and CEO of AIM7, a health and fitness app that unlocks the power of wearables by providing you with daily personalized recommendations to enhance your mind, body, and recovery. SUPPORT & CONNECT Instagram - https://www.instagram.com/erikkorem/ Twitter - https://twitter.com/ErikKorem LinkedIn - https://www.linkedin.com/in/erik-korem-phd-19991734/ Facebook - https://www.facebook.com/erikkorem Website - https://www.erikkorem.com/ Newsletter - http://link.aim7.com/adaptation-newsletterSee omnystudio.com/listener for privacy information.

In Episode 16 of the Tenkara Angler Level Line Podcast Anthony Naples talked with Jonathan Antunez about his style of active wet fly fishing that is inspired in part by H.C. Cutcliffe and other anglers of bygone eras but which is being given new life by utilizing modern state-of-the-art fixed line tenkara rods. In Episode 19 Anthony revisits this topic with Jonathan. We hope that you catch the bug like he has and you give this style of fishing a try. Show Notes: The art of trout fishing on rapid streams⁠ by H.C. Cutcliffe Check out ⁠these videos by Adam (Fly Anorak) on YouTube⁠ to see some more Cutcliffe patterns and learn more about them. Paul Gaskell's book on Amazon: Fly Fishing Master H.C. Cutcliffe Rediscovered in The Art of Trout Fishing in Rapid Streams Nikko Area tenkara fly as discussed by Jonathan on Yoshikazu Fujioka's website Discover Tenkara's Wet Flies in Focus Series on H.C. Cutcliffe's stiff-hackled wet flies Jonathan Antunez's ⁠"Trout Conjurer"⁠ Instagram account Want to see more? Visit ⁠⁠Tenkara Angler

Support the show and get 50% off MCT oil with free shipping – just leave us a review on iTunes and let us know!Your gut is not just involved in your gastrointestinal health. It also influences your metabolism, immune response, and even brain health. Dr. Colleen Cutcliffe, a microbiome scientist and CEO of Pendulum Therapeutics, reveals the surprising connections between the 100 trillion microbial cells in our gut and nearly every aspect of our health and longevity.After her daughter received multiple rounds of antibiotics as a preemie, Dr. Cutcliffe began to see the links between early antibiotic exposure and later chronic illnesses like diabetes, obesity, allergies, asthma, ADHD, and celiac disease - all centered around a decimation of the microbiome early in life. This launched her into microbiome science and the founding of Pendulum Therapeutics.Now, armed with DNA sequencing technology, Dr. Cutcliffe and her team are uncovering the key players in the gut microbiome, like the "next frontier" strain Akkermansia Muciniphila. They're developing targeted probiotics with the power of pharmaceuticals and the safety of traditional probiotics.Tune in to discover the interconnections of the gut-brain axis, the gut-metabolism axis, and why diversity in your microbiome is essential for healthy aging. Guest Bio:Dr. Colleen Cutcliffe is a biochemist, microbiome scientist, and the CEO and co-founder of Pendulum Therapeutics. She received her PhD in biochemistry and molecular biology from Johns Hopkins University and has over 25 years of experience managing biology teams in pharma, biotech, and academia. Pendulum Therapeutics is pioneering microbiome-targeted products with the efficacy of pharmaceuticals and the safety of probiotics to help restore metabolic health.Resources:Discover the groundbreaking ESS60 molecule, proven to extend life by 90%, at MyVitalC.com.Connect with Dr. Colleen Cutcliffe:- Website: https://pendulumlife.com/ - LinkedIn: https://www.linkedin.com/in/colleen-cutcliffe-9021449/ Connect with Christopher Burres- Website - https://www.myvitalc.com/- Website - https://www.livebeyondthenorms.com/- Instagram - https://www.instagram.com/chrisburres/- TikTok - https://www.tiktok.com/@myvitalc - LinkedIn - https://www.linkedin.com/in/chrisburres/

Glucagon-like peptide-1 (GLP-1) is a hormone naturally produced in the intestines during meals. It helps regulate blood sugar and weight by increasing insulin, slowing stomach emptying, and promoting fullness. Medications like Ozempic® and Wegovy® mimic the effects of GLP-1 but can be expensive and have unpleasant side effects. Listen in this week as Dee explores research on foods and probiotics that naturally boost GLP-1, offering similar benefits without the high costs and side effects.References:De Silva, A., & Bloom, S. R. (2012). Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity. Gut and Liver, 6(1), 10–20. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286726/Hira, T., Trakooncharoenvit, A., Taguchi, H.;,Hara, H. (2021). Improvement of glucose tolerance by food factors having glucagon-like peptide-1 releasing activity. International Journal of Molecular Sciences, 22(12), 6623. https://www.mdpi.com/1422-0067/22/12/6623Perraudeau, F., McMurdie, P., Bullard, J., Cheng, A., Cutcliffe, C., Deo, A., Eid, J., Gines, J., Iyer, M., Justice, N., Loo, W. T., Nemchek, M., Schicklberger, M., Souza, M., Stoneburner, B., Tyagi, S., & Kolterman, O. (2020). Improvements to postprandial glucose control in subjects with type 2 diabetes: A multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation. BMJ Open Diabetes Research and Care, 8(1), e001319. https://drc.bmj.com/content/8/1/e001319Link to purchase GLP-1 Probiotic: https://pendulumlife.com/products/glp-1-probiotic

As a little crossover with the Kaiju History podcasts on our other show, we have a Victorian tale of a chap who discovers a living fossil. But unfortunately, this surviving saurian is extremely large and very hostile...  --- Send in a voice message: https://podcasters.spotify.com/pod/show/hypnogoria/message

Episode 16 of the Tenkara Angler Level Line Podcast is doing double duty as a "Supersized" edition of the Tenkara Moves series. In this episode Anthony talks to Jonathan Antunez about fishing wet flies with tenkara rods. Jonathan offers up insight and advice on both taking wet fly fishing back to its fixed line origins while also bringing it up to the state-of-the-art utilizing modern tenkara rods and lines. Show Notes: The art of trout fishing on rapid streams by H.C. Cutcliffe Check out these videos by Adam (Fly Anorak) on YouTube to see some more Cutcliffe patterns and learn more about them. Patagonia video featuring the traditional Italian fixed-line style called Pesca alla Valsesiana Jonathan Antunez's "Trout Conjurer" Instagram account Want to see more? Visit ⁠Tenkara Angler

I am delighted to have Dr. Colleen Cutcliffe, the CEO and Co-founder of Pendulum, joining me today.  Dr. Cutcliffe is a proud alumnus of Johns Hopkins, with over 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotech. Before starting Pendulum, she was the Senior Manager of Biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals.  In our discussion today, we dive into the emerging science of the gut microbiome, examining the effects of aging, antibiotics, nutrition, stress, travel, and menopause on gut health and discussing how vaginal and C-section deliveries differ in impact. We explore differentiators for various categories of bacteria and the roles of butyrate and fiber, looking at fecal transplants and the difference between probiotics, prebiotics, and post-biotics, and explaining why Akkermansia is an essential bacteria for regulating insulin satiety, fortifying the mucin layer, and facilitating targeted delivery of butyrate. Dr. Cutcliffe also shares her top tips for mitigating the effects of travel on the gut microbiome and offers a special discount for listeners.  I am confident that you will find today's discussion with Dr. Colleen Cutcliffe engaging and enlightening. Stay tuned to learn how to adjust your lifestyle for a healthier gut microbiome. IN THIS EPISODE YOU WILL LEARN: The benefits of a vaginal delivery Various factors that disrupt the gut microbiome Why it is essential to get enough fiber in your diet What are the signs and symptoms of an unhealthy gut microbiome? The benefits of fecal transplants How the vagus nerve fosters communication between the gut and brain Why artificial sweeteners might not be as harmful to the gut microbiome as previously thought How prebiotics, probiotics, and postbiotics are interconnected and necessary for overall health The role of Akkermansia in the gut microbiome How to maintain a healthy gut microbiome while traveling   Bio: Dr. Colleen Cutcliffe: Colleen Cutcliffe, PhD, is the CEO and Co-Founder of Pendulum. She has over 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Before starting Pendulum, Colleen was the Senior Manager of Biology at Pacific Biosciences and a Scientist at Elan Pharmaceuticals. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Colleen Cutcliffe On the Pendulum Life website Use code THURLOW for 20% off your first order of Pendulum products.

In this episode, Dr. Colleen Cutcliffe, CEO and co-founder of Pendulum, delves into the vital role of the gut microbiome and Pendulum's innovative products in optimizing metabolic health. She discusses the significance of the gut microbiome in metabolic health, immune function, and beyond. Dr. Cutcliffe offers practical advice for individuals navigating antibiotic treatments and emphasizes the importance of choosing high-quality probiotic supplements. Furthermore, she underscores the benefits of continuous glucose monitors and explores the possible synergies between Pendulum's Glucose Control and GLP-1 medications such as Ozempic for enhanced outcomes. Additionally, she outlines Pendulum's research focus on improving gut metabolism and elucidating the gut-brain connection as promising avenues for future intervention. Takeaways The gut microbiome plays a crucial role in metabolic health, cardiovascular health, immune response, and brain health. Microbiome transplants have shown promise in treating obesity and other health conditions. Antibiotics and diet can significantly impact the composition of the gut microbiome. Probiotics and prebiotics can help restore and support a healthy gut microbiome. Pendulum's glucose control product has been shown to lower A1C and blood glucose spikes in people with type 2 diabetes. Continuous glucose monitors provide valuable data on how different foods affect blood glucose levels. Combining Pendulum's glucose control with GLP-1 medications may offer additional benefits. Pendulum is focused on ongoing research and development to improve metabolic health and support patients in transitioning off medications. 00:00 Introduction and Background 02:01 Pendulum's Journey and Products 04:30 What is Akkermansia? 06:43 The Importance of the Gut Microbiome 09:22 Microbiome Transplants and Obesity 14:12 Factors Affecting the Microbiome 16:12 Recovering from Antibiotic Use 18:25 Probiotics and Prebiotics 20:07 GLP-1 and Pendulum's Approach 28:53 Pendulum's A1C Study 30:41 CGM and Glucose Control 33:00 Weight Loss and Glucose Control 35:21 Butyrate and Butyrate Supplements 36:30 Future Research and Conclusion 42:11 To visit Victory Men's Health Click HERE To visit Pendulum Click HERE Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation For questions email podcast@amystuttle.com Disclaimer: The Women Want Strong Men Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

In this episode, Dr. Will Cole is joined by CEO and Co-Founder of Pendulum, Colleen Cutcliffe. With an extensive background in academia, pharmaceuticals and biotechnology, Cutcliffe set out on a mission to bridge the gap between nature and medicine through cutting-edge, all-natural, and pharmaceutical-grade microbiome products. From the science of probiotics and the gut-brain connection, top contributing factors of poor microbiome diversity, and the truth behind recently popularized weight loss drugs, to the beneficial probiotic strain you need to know about for fighting disease and maintaining a healthy gut, this episode is your go-to guide to achieve a thriving microbiome. For all links mentioned in this episode: www.drwillcole.com/podcastPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Visit PendulumLife.com and use code WILLCOLE at checkout for 20% off your first membership month. Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this interview, Dr. Jill Carnahan and Colleen Cutcliffe will explore the various aspects of Akkermansia, including its function in the gut, its role in supporting glucose control, and the innovative Pendulum Product that harnesses the power of this beneficial bacteria. Key Points Did you know that akkermansia is called a ‘keystone' strain and a key to microbial diversity Why the latest pendulum product, Glucose Control, is a game-changer when it comes to controlling your blood sugar Everything you wanted to know about losing weight naturally by increasing GLP-1 naturally in your gut. Link to Product: https://pendulumlife.com/discount/DRJILL20 Use code: DRJILL20 for 20% off membership of any product Professionals only Discount Code: WSDRJILL40

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Colleen Cutcliffe is an expert in molecular biology and co-founder of Pendulum Therapeutics, a company working to develop treatments for a variety of diseases by targeting the microbiome. In this episode, Colleen delves into the complexity of the microbiome, how it is tested, and how it changes over time. She explores how probiotics, prebiotics, and postbiotics affect the gut and makes a compelling case that well-developed products have the potential not only to enhance gut health but also to positively influence overall metabolic well-being. Colleen emphasizes the significance of a high-fiber diet in sustaining a thriving gut microbiome, shares insights on minimizing microbiome damage during antibiotic use, provides tips for fostering and preserving a healthy gut, and much more. We discuss: Colleen's background and current focus [4:45]; The basics of the microbiome [7:15]; The study of the human microbiome [15:15]; Categories of bacteria, and the implications on health of the rapid evolution of bacteria [19:45]; Methods for measuring and understanding the microbiome, and key indicators of microbiome health [28:30]; The important role of fiber for promoting gut health through the production of butyrate [38:30]; The case for manipulating gut bacteria via fecal microbiota transplant (FMT) [45:00]; Dynamics of the microbiome: the gut-brain connection and how antibiotics, nutrition, stress, and more impact the microbiome's diversity and function [50:15]; Factors that influence the vaginal microbiome [55:15]; The effect of gut microbes on obesity and challenges with fecal transplants in people [58:45]; Beneficial strains of gut bacteria and strains commonly found in probiotics [1:01:15]; The difference between a probiotic and prebiotic, and how CFUs are a measure of the “active ingredient” [1:09:45]; Considerations about how probiotic strains are produced, and more on the meaning of CFU [1:14:15]; Mitigating the effect of antibiotics on the microbiome [1:22:30]; What do we know about the effect of artificial sweeteners on the gut microbiome? [1:30:00]; Why Akkermansia is a keystone strain with implications for metabolic health and an individual's response to dietary interventions [1:36:15]; The essential steps necessary to develop a robust probiotic for optimal health support [1:45:45]; How Akkermansia helps control blood glucose, and potential implications of Akkermansia in weight loss, diabetes management, and more [1:48:45]; Pendulum Therapeutics' commitment to rigorous product develop [2:06:30]; Details about the probiotic “Glucose Control” and other probiotics developed by Pendulum Therapeutics [2:13:00]; Further studies of Akkermansia that have been proposed or are underway [2:20:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

What happens to your gut health when you take antibiotics?   In this episode of the Biohacking Superhuman Performance podcast, we chat with Colleen Cutcliffe of Pendulum Life about the effects of our gut microbiome on our mental health, metabolism, energy levels, and learn to pinpoint signs of compromised gut health.   Colleen dissects the nuances of probiotics, prebiotics, postbiotics, and synbiotics, and how these elements interact in our gut. Additionally, we examine the often-underestimated impact of antibiotics on our microbiome and how it can be combated with effective strategies.   Lastly, we shift our focus to a specific strain of bacteria, known as akkermansia, and explore their role in food metabolism and mood regulation. In the same vein, we contemplate on the potential risks of long-term drug use including GLP-1, and delve into the impact of metformin on gut health.    Colleen Cutcliffe is the CEO and Co-Founder of Pendulum Therapeutics. Colleen has over 20 years of experience managing and leading teams in biotech, pharma and academia. Prior to that, Colleen was a Scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral research at Northwestern's Children's Memorial Hospital, received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and received her B.A. in Biochemistry from Wellesley College.   Thank you to our sponsors for making this episode possible:   Healthgevity: Go to healthgev.com and use code LONGEVITY to save. Berkeley Life: Go to berkeleylife.com and use code NIDDBL to save. LVLUP: Go to lvluphealth.com and use code NAT10 for 10% off your order. Find more from Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance  Instagram: https://www.instagram.com/nathalieniddam/  Website: NatNiddam.com   Join Nat's Membership Community: https://www.natniddam.com/bsp-community  Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Colleen:   Website: https://pendulumlife.com/  Facebook: https://www.facebook.com/PendulumLife  Instagram: https://www.instagram.com/pendulumlifeco/  Linkedin: https://www.linkedin.com/company/pendulumco/  Twitter: https://twitter.com/Pendulum_Co  What we discuss:   (00:02) - Gut Health and Mental Health Connection (07:43) - Understanding Gut Health and Microbiome Terminology (19:16) - The Battle of Diets and Nutrition (26:37) - Antibiotics' Impact on Microbiome and Rebalancing Strategies (35:37) - Gut Microbiome and Healthy Aging (44:30) - Risks of Long-Term Antibiotic Use (58:39) - Benefits and Challenges of Akkermansia  (01:04:49) - Live Probiotics and Colonization Importance   Key takeaways:   Nutrition is an important part of gut health. However, there isn't a particular diet that will make or break your gut health nor can you eat a nutrient-poor diet and expect probiotic supplements to keep your gut microbiome in good shape. Simply aiming to eat a balanced, nutrient rich diet is the way to go. While antibiotics have a negative impact on your gut health, it does come with a plus side. Given that antibiotics eliminate all bacteria – good and bad – the timeframe following an antibiotic treatment is a great time to focus on fixing your diet so you can repopulate your gut microbiome with the appropriate strains. While many of us blame our poor willpower for our cravings, it's usually our gut microbiome that is to blame. Luckily, there are specific strains one can supplement to help increase GLP-1 and GABA production to stimulate satiety and reduce anxiety, which helps reduce cravings overall.  

A Five Part Series on Hallowed Waters Podcast “Below the Meniscus”- The Evolution and Art of Fly Fishing Below the Surface with Nymphs and Wet Flies – A Five Part Series on Hallowed Waters Podcast From its Roman Empire era origins in Macedonia with the Red Fly, and early beginnings with Dame Juliana and her “Treatise” dangling her beautifully concocted flies to fool trout and Atlantic salmon on the River Ver spring creek at her St Alban's Sopwell Nunnery, is how fly fishing had its humble beginnings. But it was with the modern foundations of Ronalds, Skues, Sawyer, and Cutcliffe in England,  on the hallowed chalk streams of the Rivers Itchen and Avon; and North Country, Wales  and Dartmoor small freestone rivers, that the nymph and wet fly had their evolution. Thus the going below the meniscus art form has now become the most lethal way of taking trout worldwide with the onset of Euro Nymphing. Three accomplished guest figures of these genres: ex- pat Davy Wotton, George Daniel, and one of England's iconic chalk stream fly fishing authors, Terry Lawton, along with Hallowed Waters Podcast host and author: Matthew Supinski, discuss the evolutionary magnitude, science, artistic beauty, techniques and gear, fly designs, but often questionable approaches with Euro and competitive fishing,  that impacts the trout and fly fisher with these highly effective tactics. The final episode discusses the impact on the angler and how it has transformed them from a fly shop and consumer's perspective, with a highly skilled Euro nympher and fly shop guru guest: Torrey Collins. Don't miss this  epic documentary podcast on the subject – stay tuned! hallowedwatersjournal.com ARPOW Instagram https://www.instagram.com/arpowmusic/?hl=en Apple Music Link https://music.apple.com/us/album/floating/1538035394?i=1538035453 Caleb Instagram https://www.instagram.com/iamcalebdenman/ Jupiter Sound Instagram https://www.instagram.com/jupitersoundllc/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/hallowedwaters/message Support this podcast: https://podcasters.spotify.com/pod/show/hallowedwaters/support

Colleen Cutcliffe, co-founder and CEO of the groundbreaking probiotics company Pendulum Therapeutics, started the company with a big goal in mind: changing the way people think about their gut health. And on her journey, she's had to challenge traditional – and sometimes outdated – thinking from the medical community and investors. In this episode, Colleen told us how she's been able to disrupt the industry, and gives her advice for making changes in any workplace.  In this episode, Colleen shares:  How she convinced the dean of her PhD program to let her stay – despite almost getting kicked out  Why her daughter's birth inspired her to start Pendulum  How she dealt with being told “no”  The ways she's cultivated trust and transparency with her team Why she's got Halle Berry on speed dial  PS: Skimm'rs get 20% off their first month of any Pendulum product(s) with code SKIMM9TO5.

In this episode of Habits and Hustle, I chat with Colleen Cutcliffe who gives us a step-by-step guide on all things gut health – understanding why optimization is key, why it's growing in popularity, how your gut is controlling you, and exactly what you should do to reclaim your gut microbiome. We also dive into how the gut is linked to your metabolism, the popular trend of glucose control and why we should be concerned about our glucose levels, and why an increasing number of people are seeking natural alternatives to metformin. Colleen Cutcliffe is the CEO and Co-Founder of Pendulum Therapeutics. Colleen has over 20 years of experience managing and leading teams in biotech, pharma, and academia. Before starting Pendulum Therapeutics, Colleen served as the Senior Manager of Biology at Pacific Biosciences, which is where she met her two co-founders. Prior to that, Colleen was a Scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral research at Northwestern's Children's Memorial Hospital, received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and received her B.A. in Biochemistry from Wellesley College. Use code “JENCOHEN” for 20% off of your first bottle of membership at pendulumlife.com What we discuss: (0:09:01) - Akkermansia's Role in Gut Health (0:17:41) - GLP-1 and Akkermansia in Metabolism (0:31:36) - Longevity Drugs and Glucose Control (0:35:01) - Glucose Control and Metabolic Supplement Benefits (0:45:16) - Gut Health Benefits and Quality Control (0:57:15) - Understanding Acromantia and Its Benefits Thank you to our sponsors: Pendulum: Head over to www.pendulumlife.com and use code JENCOHEN for 20% off. Therasage: Head over to therasage.com and use code Be Bold for 15% off Ketone IQ (HVMN): You can save 30% off your first subscription order of Ketone-IQ at HVMN.com/JEN Find more from Jen:  Website: https://www.jennifercohen.com/ Instagram: @therealjencohen  Books: https://www.jennifercohen.com/books Speaking: https://www.jennifercohen.com/speaking-engagement Learn more from Colleen Cutcliffe: Website: https://pendulumlife.com/ Instagram: https://www.instagram.com/pendulumlifeco/ Learn more about your ad choices. Visit megaphone.fm/adchoices

It's time for a gut check! Morgan's guest this week is Dr. Colleen Cutcliffe, a biochemist and molecular biologist who is passionate about gut health. Colleen is the co-founder and CEO of Pendulum, a research-driven probiotics company on a mission to improve overall health by focusing on the gut. Learn more about the connection between balanced gut flora and a healthy body, and why she believes that certain probiotic strains (particularly Akkermansia) are the key to a healthy gut. Colleen also shares with Morgan the impact that stress, aging, and early antibiotic use can have on the gut microbiome and what people can do to get their gut back in check.

Here we discuss how to measure your gut microbiome, what the future of probiotic and gut microbiome research may hold and what Dr Cutcliffe's personal regimen is.

Metabolic Daily is a less potent but more available form of the Glucose Control probiotic used in the clinical trial. Dr Colleen Cutcliffe discusses the differences in the formulations, the best time to take and what effects people have seen

We talk to Dr Colleen Cutcliffe about a clinical trial that they ran with 5 strains of probiotic. We also talk about whether the strains remained resident and what are the best prebiotics for akkermansia.

We talk to Dr Colleen Cutcliffe about akkermansia muciniphila a probiotic that is involved in Some links are affiliate links so we will earn a commission when they are used to purchase products.

Join us on the latest episode! Our Guest: Colleen Cutcliffe, Co-Founder & CEO at PendulumWhat you'll get out of this episode: Metabolic health and microbiome science. Colleen's science background with a focus on improving gut health. Importance of gut microbiome in metabolizing sugars, carbs, and overall health. Pendulum's mission to restore and enhance gut health, addressing depletion of beneficial bacteria. Future potential of probiotics, including convenient drink formats, for improved well-being. To learn more about Pendulum Life: https://pendulumlife.com/Our sponsors for this episode are:Sage Growth Partners https://sage-growth.com/FlipMD by GoodRX https://www.goodrx.com/Quantum Health https://quantum-health.com/WHAT IS SLICE OF HEALTHCARE?The go-to site for digital health executive/provider interviews, technology updates, and industry news. Listed to in 65+ countries.

In this podcast, Dr. Colleen Cutcliffe, a PhD scientist and the co-founder and CEO of the microbiome company, Pendulum Therapeutics, discusses the role that different bacterium such as Akkermansia play in optimal gut health and function. Click here to view episode transcript: https://www.ifm.org/news-insights/akkermansia-gut-health-with-dr-colleen-cutcliffe/

Dr. Colleen Cutcliffe, Cofounder and CEO of Pendulum Therapeutics, is leading a dedicated team in their pursuit of groundbreaking and transformative solutions for gut health-related ailments, showcasing a remarkable passion for improving people's lives through revolutionary, safe, and effective microbiome interventions. In today's episode with Dr. Colleen Cutcliffe, you'll hear us take a deep dive on: 1. The evolution of antibiotics and how their broad spectrum also harms the gut microbiome, potentially causing long-term issues like food sensitivities, chronic illnesses, and conditions beyond the digestive system, such as obesity and neurological disorders. 2. The recent discovery of the keystone probiotic strain Akkermansia, which resides in the gut lining, and its crucial role in preventing gut lining deterioration. 3. Akkermansia's benefits, including producing proteins that stimulate GLP-1, a hormone involved in regulating insulin and glucose response to prevent high glucose spikes and promote weight loss. 4. How neurons in the gut communicate with the brain, influencing cravings and other functions, and recent studies indicate that neurological conditions like Parkinson's and Alzheimer's may manifest in gut neurons before brain cells. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide Use code root20 for 20% off of your next purchase of Akkermansia - bit.ly/3p8qxkn

In this episode of the Thrive State Podcast, Dr. Kien Vuu (Doctor V) sits down with Dr. Colleen Cutcliffe, an expert in the microbiome and co-founder of Pendulum Therapeutics. They discuss the critical role of the microbiome in overall health, ways to optimize it, and the future of microbiome research. Discover practical tips and strategies for improving your gut health and overall wellbeing.   Get 20% off your first order of Pendulum with code THRIVE20.    Don't forget to follow Doctor V @doctorvmd, grab a copy of the #1 Amazon bestseller Thrive State at thrivestatebook.com, and download a free longevity guide at thriveto105.com.   Episode Highlights: Dr. Cutcliffe's journey into microbiome research The importance of the microbiome in overall health How lifestyle choices impact the microbiome Strategies for optimizing your microbiome The future of microbiome research

In this episode of One day with Jon Bier, Jon talks with Colleen Cutcliffe to break down the complexities of microbiome science. Listen in as Colleen highlights the importance of replenishing and maintaining a thriving gut microbiome in a modern society that overlooks its role as a cornerstone of health and wellness. She discusses the importance of the bacterium Akkermansia and why its regulation is key to gut health. Finally, Colleen discusses signs to look for which indicate a recovering microbiome, and how to ensure that recovery following chemo or taking an antibiotic. Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. Colleen has more than 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to co-founding Pendulum, Colleen was the senior manager of biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals. Powerful Quotes by Colleen There are so many diseases that are associated with the depletion of Akkermansia that it's emerging as this keystone strain that you simply have to have. After you take an antibiotic, your microbiome is in its most vulnerable state. You have a blank slate, and what you decide to feed it now can make or break the playing field. Key Highlights A healthy microbiome “covers” us in bacteria, viruses, and fungi in order to be protected from allergens that are always present in our environment. Because of our modern focus on scrubbing ourselves clean of these bacteria, those allergens have the opportunity to directly interact with our immune system. This is why we're experiencing an increase in allergies, asthma, immune and autoimmune responses. Multiple studies, including one by Mayo Clinic, reveal that children who are consistently on antibiotics are systematically more prone to obesity, diabetes, celiac disease, allergies, ADHD, etc. This is all due to their microbiome being unable to recover from the prolonged administration of antibiotics. The microbiomes of the healthiest people are composed of 3-5% Akkermansia, which is a huge number for a single strain. Episode resources: Go to getneuro.com and use code “ONEDAY” at checkout for 15% off your entire order! Connect with Colleen Cutcliffe LinkedIn: Colleen Cutcliffe Connect with Jon Bier Instagram: @jonbier13 Twitter: @jonbier13 Facebook: @jonbier13

#sponsoredepisodeDid you realize how much your gut microbiome influences your metabolism, your weight and your overall health? Dr. Whitney talks with Colleen Cutcliffe, PhD, CEO and Co-Founder of Pendulum Therapeutics about how the gut microbiome works, optimizing the way your body handles the nutrients you consume, and choosing a probiotic that really works. Colleen Cutcliffe, PhD, is the CEO and Co-Founder of Pendulum. She has over 15 years of experience leading and managing biology teams in academia, pharmaceuticals and biotechnology. Prior to starting Pendulum, Colleen was the Senior Manager of Biology at Pacific Biosciences and a Scientist at Elan Pharmaceuticals. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College.You can find out more at www.modernmommydoc.com/podcastAbout Pendulum:Pendulum optimizes the metabolism of sugar and carbohydrates, reducing sugar cravings and energy slumps, boosting sugar and carb metabolism, AND supporting a healthy weight. Pendulum understands that whole-body health and wellness is tied to the complex ecosystem of microorganisms that is the microbiome, and that addressing imbalances in the microbiome transform people's lives from the inside.Their mission is simple: to improve the lives of millions through microbiome products. To that end, they create products that have the power and efficacy of a pharmaceutical with the safety and accessibility of a probiotic.To accomplish their mission, they developed an entirely new product–a medical probiotic. Medical probiotics are the bridge between nature and medicine, helping restore our bodies to their peak balance.To learn more about Pendulum Therapeutics AND to get 20% off your first month of Pendulum membership, go to www.pendulumlife.com and use code MODERN20

Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Colleen and her company Pendulum Life probiotics make unique strands of probiotics that help rebuild the gut lining and prevent leaky gut and help reverse type-2 diabetes. A double-blind randomized control study showed that users taking Pendulum's Glucose Control probiotic had a reduction in A1C by 0.6% and a reduction postprandial glucose spikes by 32.5%. Clearly there is more to weight loss than just calories in and calories out.Go to www.pendulumlife.com to get your probiotics and use the code "HACKED" in checkout for a discount. Timeline2:30 - What's wrong with the probiotic industry4:11 - Why most probiotics don't work5:35 - How Pendulum's probiotic works?12:52 - How Pendulum probiotics affect the brain14:46 - Can I still take Pendulum if I don't have weight issues?17:03 - How Pendulum affects cravings and is GLP agonist19:15 - How long does it take to see the effects22:16 - What happens if you stop taking it?25:32 - An explanation of Pendulums three products28:50 - Metformin versus Pendulum probiotics32:55 - Why butyrate is so important34:20 - New product coming soon with polyphenols35:40 - Why the products can appear pricey

IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She's a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia's back in the spotlight, with more than 300 new studies showing connections to weight, metabolism and immunity. A unique and novel probiotic strain (species of bacteria) naturally found in your gastrointestinal tract, Akkermansia muciniphila, directly interacts with your gut lining and helps regulate the mucus lining in your gut. Now, there's growing evidence showing Akkermansia to be a keystone bacterial strain.This conversation dives into the latest research and what it means for you. You'll learn how to apply this new knowledge and how to boost Akkermansia in your gut.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code DAVEVIP to get 20% off your first month of membership. Watch this episode on YouTube!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia's Holiday 25% off sale. Through Dec. 31, 2022, only. Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

70% of your immune system is located in your gut- how are you supporting your microbiome for your best health? Colleen Cutcliffe, PhD, CEO and Founder of Pendulum joins on episode 39 of the Practically Healthy podcast to provide a science-based discussion on probiotics and how this rapidly emerging field is playing an important role in health and disease. Colleen shares the research and insights that lead to Pendulum's revolutionary probiotic, Akkermansia for mitigating metabolic syndrome. She explains that the Akkermansia muciniphila strain plays an important role in metabolism and the gut lining. The listener learns why low counts or depletion of Akkermansia is a problem, and can result in Inflammation, skin disorders, immune response and metabolism disorders. Dr. Melina reveals that she orders Akkermansia and mentions that it can reduce sugar cravings, anecdotally, for some. Colleen and Dr. Melina discuss science-based gut health facts and tips including significant factors that influence your microbiome other than diet, and foods you should avoid for your best gut health. The role of prebiotics, in concert with probiotics is addressed and Colleen shares research that gives insight into whether you need to keep taking probiotics or can discontinue once the microbiome is recolonized. The listener is cautioned about the lack of oversight in the supplement industry and practically healthy tips are shared to assist the listener in choosing a probiotic. Colleen offers listeners a free quiz on Pendulumlife.com to assess which Pendulum probiotic is best for their personal needs. Practically Healthy listeners receive a discount with code DRMELINA at Pendulumlife.com.

CEO and Co-Founder of Pendulum Life - Colleen is on a mission to heal, recover, and optimize our 2nd Brains!! (aka - our gut!)  If you have ever had an issue with gut health, brain fog, or just want to know how to have the highest functioning gut to brian relationship possible, this is the episode for you! We go in-depth on what this new thing called Akkermansia is (legit unreal how great it is for your gut repair!) and what everyone wants to know - how to control glucose, so you don't add on unwanted fat!!  Check out the episode and let Colleen and me know your questions, takeaways, and thoughts! (and get your super discount on Pendulum Life Products right here!)  https://pendulumlife.com/ CODE: DAVID20 for 20% off storewide! Learn more about your ad choices. Visit megaphone.fm/adchoices

This week's conversation is with Dr. Colleen Cutcliffe, the CEO and Co-Founder of Pendulum Therapeutics.Colleen's extensive background includes a doctorate in Biochemistry and Molecular Biology from Johns Hopkins University, and over 20 years of experience managing and leading teams in biotech, pharma, and academia.In 2013, Colleen left her position as Senior Manager of Biology at Pacific Biosciences to start Pendulum, a company on a mission to improve health through first of its kind research and development in the gut microbiome.Pendulum's next generation probiotics are pioneering ways for people to transform their health and wellness by unlocking the power of the gut microbiome.I've been studying gut health and the microbiome for a long time now, and it's clear that Pendulum is on the forefront of creating meaningful change for people.I was fascinated to learn more about the topic from Colleen, and I hope you leave this conversation with a better understanding of the gut microbiome, and some applied insights on how improving your gut health can improve your life.-----Please support our partners!We're able to keep growing and creating content for YOU because of their support. We believe in their mission and would appreciate you supporting them in return!!To take advantage of deals from our partners, head to http://www.findingmastery.net/partners where you'll find all discount links and codes mentioned in the podcast.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Skateboarder and Bama native Daniel Cutcliffe drops by to talk about growing up in Birmingham, video parts through the years, fights at Homewood park, life in Charleston, injuries, sponsors, contests, and traveling the world through skateboarding.

Colleen Cutcliffe, CEO and Co-Founder of Pendulum Therapeutics, joins Chris on this episode of Revolution Health Radio to discuss how metabolic health is related to the gut microbiome, microbiome research, and probiotics. They'll talk about the problem with current probiotics, the opportunities being presented by novel strains and formulations, innovations in understanding the gut–metabolic and gut–brain connections, and the challenges of bringing anaerobic probiotics to the marketplace. The post RHR: The Microbiome Approach to Better Probiotics, with Colleen Cutcliffe appeared first on Chris Kresser.

Many of us in the functional medicine space are thinking about Akkermansia: what exactly makes this gut bug a keystone strain for health and longevity? I am excited to tackle this with a founder of Pendulum Therapeutics, Colleen Cutcliffe, PhD, an excellent scientist and a leader in biotech. Her passion to help her daughter, and many others, overcome food sensitivities inspired Colleen to use biotech and research to develop products that have the efficacy of a drug, but the safety of a probiotic. We cover it all, and then some! Enjoy, and let me know what you think. ~DrKF

Dr. Hunter A. Taylor is a Clinical Assistant Professor in the School of Education and an Affiliated Faculty Member in the Center for the Study of Southern Culture at the University of Mississippi (UM). He is also the Inaugural Scholar-in-Residence for the Oxford School District. In these roles, he teaches and advises administrators, teachers, coaches, and policymakers from across the state. Before joining the UM faculty, he spent 10 years as a men's basketball coach and two years as a U.S. Senate staffer. Taylor has also published two leadership books. The first, How to Build a Thick Institution, comes from a TED talk that Taylor gave with Coach Chris Cutcliffe about how they improved Cutcliffe's high school football program and eventually captured the 2019 Mississippi 6A state championship. It is a reflection on the leadership strategies the duo implemented together. His second, Draw the Line, examines the impact a high school football staff made in rural East Texas over the course of 20 years. The book is told through the lens of current UTSA head football coach Jeff Traylor and his long-time colleagues. Twitter: @DrHunterTaylor IG: @hunter_a_taylor www.huntertaylor.design Social Media Links Youtube Channel youtube.com/c/ChipBakerTheSuccessChronicles LinkedIn http://linkedin.com/in/chipbakerthesuccesschronicles Facebook- Profile https://www.facebook.com/tscchipbaker Facebook- Page facebook.com/chipbakertsc Instagram https://www.instagram.com/chipbakertsc/ Twitter twitter.com/chipbaker19 TikTok tiktok.com/@chipbakertsc Linktree https://linktr.ee/ChipBakerTSC Online Store http://chip-baker-the-success-chronicles.square.site/ Chip Baker- The Success Chronicles Podcast https://anchor.fm/chip-baker

After a bit of trash talk on Twitter, Coach Symmes took some time out of a Wednesday evening to talk about ECU football, his coaching career in college and the NFL and, of course, Duke football. Coach Symmes coached at Duke during the Cutcliffe era before moving onto Indiana where he worked with current Blue Devil OC Kevin Johns. Coach Symmes also had stops at Florida, USC (the one in South Carolina) and with the Pittsburgh Steelers. During this informative conversation, you'll learn about what a defensive analyst does, the challenging life of a coach and what made the 2013 Duke team so special. We'll give Symmes a pass for thinking that Indiana made the field goal at the end of the Pinstripe Bowl. I think his glasses were broken or something. Oh, and we mention Miami. Blerg. Go Duke! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/bullcitycoordinators/support

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideSkin Health and Healing: https://alituranaturals.com/shop/, use code DAVE20 for 20% off storewideBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code "DAVEVIP" to get an exclusive discount.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you'll learn about emerging science that points to the effects of sugar on your gut microbiome and metabolism and the connections between sugar, your mental acuity and longevity.Biochemist and molecular biologist Colleen Cutcliffe, Ph.D., continually searches for new ways to improve your gut health and help you live longer. As CEO and co-founder of Pendulum Therapeutics, she works to turn scientific discoveries into real products that hack and heal your microbiome and its associated body systems. At Pendulum, her team identifies and isolates new bacterial strains then combines those new strains to create unique probiotics.“We really worked hard on ways to modulate post-postprandial glucose spikes through the microbiome,” Colleen says. The result? Pendulum's Glucose Control lowers blood glucose spikes by 33 to 34% for people with type 2 diabetes. “What we didn't realize was how many people who don't have type 2 diabetes were going to end up benefiting from it.”This conversation homes in on sugar management and a broad range of research that's exploring what you can do about managing your glucose to keep up your mental acuity (less brain fog, sharper thinking) and live a longer life. Science has discovered that as you age:You have reduced ability to metabolize sugar. Your microbiomes become less diverse and depleted of certain key strains that are important for sugar metabolism.If you improve glucose control, you see reduced neuronal inflammation and improved cognition.In the past decade, especially, sugar dominates a lot of the conversation around diet and health. It's been studied, substituted, moderated, restricted and demonized. With that type of focus, you lose the bigger point. “You can't completely cut out sugar,” Colleen says. “You do need sugar. Not all sugar is bad for you all the time. Every cell in your body, except for your colon cells, need glucose in order to survive, in order to replicate, in order to perform functions. All of the things that allow you to be a human being require some amount of sugar."She wants you to know what's happening to cause the change in metabolic processing as you age and what you can do about it, like:How to understand your blood glucose range and what fluctuations mean.How to track your blood glucose and what to do about peaks and dips.How to improve your focus, sharpness and mental endurance through diet and fitness.“I'm a scientist, so I'm always going to say more data is better,” Colleen explains. “[Especially] when you're trying to make improvements and you're making these micro-adjustments in your life, and you want to understand what impact are they having.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

ACC Network college football analyst Roddy Jones joins the N&O's Jonas Pope IV to explain why N.C. State football fans should feel better entering the 2022 season than UNC fans prior to last season. They also discuss if the Wolfpack's Devin Leary could be the top quarterback in the ACC this season, how the Tar Heels bounce back from last year's 6-7 season, why losing Sam Howell may not be bad for Carolina and who could be next up at QB for Mack Brown's program. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, I talk with Colleen Cutcliffe, PhD, CEO and Co-Founder of Pendulum Therapeutics, a microbiome solutions company based in San Francisco, CA. Pendulum has developed two live microbial therapies, Pendulum Glucose Control for the management of type II diabetes, and Pendulum Akkermansia for the support of gut health. Dr. Cutcliffe has over 20 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. She received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University, and her B.A. in Biochemistry from Wellesley College. In our conversation we discuss a number of questions related to live microbial therapies and next generation probiotics, including the following: · How did Pendulum get into the business of live microbial therapies? · How effective is this Pendulum Glucose Control for the treatment of type II diabetes, and what is the evidence? · For which patients is Glucose control indicated? · What is the evidence for the effectiveness of Pendulum Akkermansia for gut health? · How do you assess gut health? · How do you see the future of next generation probiotics in the treatment of chronic medical disorders? If you'd like to learn more about Pendulum's products, you can use my affiliate link here & if you buy a membership, you can take 20% off with code: EMERAN. As always, if you have any questions or comments, leave them below, and if you're enjoying our content, please take a second to like the video! Follow Dr. Mayer: https://linktr.ee/emayer

In this episode, I talk with Colleen Cutcliffe, PhD, CEO and Co-Founder of Pendulum Therapeutics, a microbiome solutions company based in San Francisco, CA. Pendulum has developed two live microbial therapies, Pendulum Glucose Control for the management of type II diabetes, and Pendulum Akkermansia for the support of gut health. Dr. Cutcliffe has over 20 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. She received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University, and her B.A. in Biochemistry from Wellesley College. In our conversation we discuss a number of questions related to live microbial therapies and next generation probiotics, including the following: · How did Pendulum get into the business of live microbial therapies? · How effective is this Pendulum Glucose Control for the treatment of type II diabetes, and what is the evidence? · For which patients is Glucose control indicated? · What is the evidence for the effectiveness of Pendulum Akkermansia for gut health? · How do you assess gut health? · How do you see the future of next generation probiotics in the treatment of chronic medical disorders? If you'd like to learn more about Pendulum's products, you can use my affiliate link here & if you buy a membership, you can take 20% off with code: EMERAN. As always, if you have any questions or comments, leave them below, and if you're enjoying our content, please take a second to like the video! Follow Dr. Mayer: https://linktr.ee/emayer

The Duke Football program struggled for another week and despite showing progress offensively and on special teams, it can't seem to put a complete game together. Locked On Blue Devils Host JJ Jackson joins the show to discuss the teams struggles and if Cutcliffe should announce his retirement prior to the Miami finale to get more fans to attend the game. Meanwhile, Duke basketball remains undefeated and has seen big performances from Paolo Banchero, Wendell Moore Jr., Mark Williams and Trevor Keels. Follow @LockedOnACC on Twitter & Subscribe on YouTube.Support Us By Supporting Our Sponsors!Built BarBuilt Bar is a protein bar that tastes like a candy bar. Go to builtbar.com and use promo code “LOCKED15,” and you'll get 15% off your next order.BetOnline AGThere is only 1 place that has you covered and 1 place we trust. Betonline.ag! Sign up today for a free account at betonline.ag and use that promocode: LOCKEDON for your 50% welcome bonus.PrizePicksDon't hesitate, check out PrizePicks.com and use promo code: “LOCKEDON” or go to your app store and download the app today. PrizePicks is daily fantasy made easy!NetSuiteOver twenty-seven thousand businesses already use NetSuite and RIGHT NOW through the end of the year NetSuite is offering a one-of-a-kind financing program to those ready to upgrade at NetSuite.com/LOCKEDONNCAA. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Colleen is a scientist with dual doctorates in biochemistry and molecular biology AND microbiome expert about healing oneself through the gut. She received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and is the co-founder of Pendulum Therapeutics. * About The Immunity Docuseries: Never has it been so critical and obvious that our health and immunity have to be a top priority. It's now up to us to make a choice: continue down a path of disease or do everything possible be to be at our peak health. Some of the questions explored in this series include: How can we be resilient to diseases and viruses to come? What actions can we take today to achieve peak immunity? What are the non-negotiables to building immunity? * This podcast wouldn't be possible without the support of Thrive Performance & Regenerative Medicine. A team prepared to go all-in with you to craft a personalized health plan to achieve your peak health. Book a free consult to start your health transformation at - https://thrivemedicineclinic.com/ * Thrive Medicine - @thrivemedicine Dr. Rhet Langley - @rhetmd Dr. Phillip Gallegos - @phillipgallegos_md Marc Champagne - @mchampagne

Use Code: MOLLIE10 – for 10% off the first bottle of a subscription order. BIO:Colleen Cutcliffe, Ph.D., is co-founder and CEO of Pendulum Therapeutics, a biotech startup in San Francisco. The company's mission is to fill the chasm that exists between unregulated supplements and prescription drugs. In this middle ground, Colleen envisions a future in which medicines are derived not from chemistry but one of nature's greatest gifts: the human body's microbiome.The safety and effectiveness of the company's first microbiome-bolstering probiotic, Pendulum Glucose Control, is welcome news for more than 120 million Americans living with diabetes and prediabetes, struggling to control their blood sugar.Colleen's pursuit is personal. Her daughter was born nearly eight weeks premature, spending the first month of life hooked up to machines. Doctors loaded her up with antibiotics, which is the standard, often lifesaving, a protocol for preemies. But the antibiotics wreak havoc on babies' microbiomes and could result in chronic conditions as adults [source]. Now 12 years old, Colleen's daughter already suffers from gut issues and food sensitivities that no one else in the family has.There has to be a better way – therapies that spare the microbiome while treating chronic conditions – and Colleen is determined to forge a new path. Prominent Silicon Valley venture capital firms are keen to help her: Sequoia Capital, True Ventures, and Khosla Ventures have invested $57 million since 2014.Colleen received a Ph.D. in biochemistry and molecular biology from Johns Hopkins University and a B.S. in biochemistry from Wellesley College. She completed her postdoctoral research at Northwestern Medicine's Lurie Children's Hospital of Chicago. Colleen lives in Menlo Park, Calif., with her husband, two daughters, and two rambunctious dogs.LINKS:https://www.instagram.com/pendulumlifeco/https://twitter.com/Pendulum_Cohttps://www.facebook.com/PendulumLife/https://www.linkedin.com/company/pendulumco/https://www.pendulumlife.comUse Code: MOLLIE10 – for 10% off the first bottle of a subscription order.  SHOW NOTES:

Colleen Cutcliffe, CEO & Co-Founder at Pendulum Therapeutics, shared the story behind her title with us on Saturday, April 10th and Sunday, April 11th, 2021.Colleen has over 15 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to starting Pendulum, Colleen was the Senior Manager of Biology at Pacific Biosciences and a Scientist at Elan Pharmaceuticals. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College.SUE SAYS"As a young girl growing up in the deep south to immigrant parents, Colleen's experience was not one of racism or discrimination. She recalls the lesson she learned from her parents was that every person, no matter their background, has the absolute power to chart their own course in life. She's taken these values of integrity, hard work and education and applied them directly to her company Pendulum. "Support this podcast at — https://redcircle.com/women-to-watch-r/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

As David Cutcliffe prepares to embark on his 13th season at the helm of the Duke Football program he'll do so as the 3rd winningest coach in school history, having already piled up 72 wins. Along the way there have been no shortage of instant classics and over the course of the next few months we'll revisit some of the great games of the Cutcliffe era as originally heard on the Blue Devil Sports Network. In this episode we look back on a water-logged night on South Beach as Duke ended a 42-year drought at Miami, thanks in no small part to the work of Ben Humphreys who offers his thoughts on the milestone victory.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As David Cutcliffe prepares to embark on his 13th season at the helm of the Duke Football program he'll do so as the 3rd winningest coach in school history, having already piled up 72 wins. Along the way there have been no shortage of instant classics and over the course of the next few months we'll revisit some of the great games of the Cutcliffe era as originally heard on the Blue Devil Sports Network. In this episode we look back at a historic afternoon in South Bend, Indiana as Daniel Jones, Anthony Nash, Jela Duncan and some fireworks on special teams from Shaun Wilson saw Duke stun the Irish 38-35.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As David Cutcliffe prepares to embark on his 13th season at the helm of the Duke Football program he'll do so as the 3rd winningest coach in school history, having already piled up 72 wins. Along the way there have been no shortage of instant classics and over the course of the next few months we'll revisit some of the great games of the Cutcliffe era as originally heard on the Blue Devil Sports Network. In this episode we look back on a double-overtime thriller from Pittsburgh in 2014, as Duke saw Anthony Boone, Jamison Crowder, Devon Edwards, and Thomas Sirk will the Blue Devils to a 51-48 win on the road.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.