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2 episodes with cytosine
2 episodes with cytosine
Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and talk about the findings of their newly published Cochrane review of interventions for quitting vaping. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research. Jamie and Nicola share the findings of their new Cochrane review of interventions for quitting vaping published in January 2025 and funded by Cancer Research UK (https://doi.org/10.1002/14651858.CD016058.pub2). This new review included nine studies in just over 5,000 participants. Studies tested nicotine replacement therapy, cytisine, varenicline, nicotine/vaping reduction and text message-based interventions. The review found that text-message-based interventions may help young people to stop vaping and that varenicline may help people to stop vaping when compared to no or minimal support. There was some promising evidence from a shorter study of cytisine. More information is needed on other interventions, on potential harms and on the effect on use of tobacco cigarettes. Twenty ongoing studies looking at a range of interventions were identified in the review. The motivation for the review and the press coverage is also discussed. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our literature searches for the EC for smoking cessation review carried out on 1st December and 1st January found 3 new studies (Kale 2024 DOI 10.1101/2024.09.13.24313612; Pericot-Valverde 2024 DOI 10.1093/ntr/ntae260; Sifat 2024 DOI 10.1016/j.dadr.2024.100295) and 3 linked studies (DOIs 10.1016/j.heliyon.2024.e39695; 10.1111/add.16698; 10.1093/ntr/ntae223) For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2024 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub8/full For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub2/full This podcast is supported by Cancer Research UK.
Follow Shane and Duncan along the twists and turns of the double helix as they unravel the history of genetics and DNA profiling. From Watson and Crick to the Human Genome Project, from Green River to the Golden State Killer, learn how genetic material holds the key to solving seemingly unsolvable crimes and curing formerly incurable diseases. ~ In this episode: Deoxyribonucleic Acid: The "Blueprint for Life" The Structure of DNA Nucleotides: Adenine, Cytosine, Thymine, Guanine Sugar Phosphates Friedrick Miescher Photo 51 Rosalind Franklin Watson and Crick The Eagle Pub Nature Magazine DNA Sequencing Frederick Sanger The Human Genome Project DNA Profiling Jeffrey Glassberg Alec Jeffries Murderer Colin Pitchfork: The First Success Restriction Fragment Length Polymorphism The Green River Killer: Gary Ridgeway The Golden State Killer: James D'Angelo Junior CODIS: The Combined Data Index System Touch-DNA The Pitfalls of Partial DNA Successes ~ Support the show by becoming a Midnight Minion, Menace, or Maniac, and unlock exclusive bonus content over at PATREON ~ Chat with fellow insomniacs and vote on episode topics via DISCORD ~ Join the Midnight Masses! Become an Insomniac by dropping a review, adding us on social media, and contacting us with episode ideas. And we now have Midnight Merch! Show your Insomniac pride and pick up a tee shirt or coffee mug to spread the word! Midnight Merch ~ Leave an Audio Message! ~ Instagram ~ Podcast Website ~ Episode Transcript
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.03.522592v1?rss=1 Authors: Singh, B. N., Tran, H., Kramer, J., Kirishenko, E., Changela, N., Wang, F., Feng, Y., Kumar, D., Tu, M., Liang, S., Lan, J., Bizet, M., Fuks, F., Steward, R. Abstract: Modifications of mRNA, especially methylation of adenosine, have recently drawn much attention. The much rarer modification, 5-hydroxymethylation of cytosine (5hmC), is not well understood and is the subject of this study. Vertebrate Tet proteins are 5-methylcytosine (5mC) hydroxylases enzymes catalyzing the transition of 5mC to 5hmC in DNA and have recently been shown to have the same function in messenger RNAs in both vertebrates and in Drosophila. The Tet gene is essential in Drosophila because Tet knock-out animals do not reach adulthood. We describe the identification of Tet-target genes in the embryo and larval brain by determining Tet DNA-binding sites throughout the genome and by mapping the Tet-dependent 5hmrC modifications transcriptome-wide. 5hmrC-modified sites can be found along the entire transcript and are preferentially located at the promoter where they overlap with histone H3K4me3 peaks. The identified mRNAs are frequently involved in neuron and axon development and Tet knock-out led to a reduction of 5hmrC marks on specific mRNAs. Among the Tet-target genes were the robo2 receptor and its slit ligand that function in axon guidance in Drosophila and in vertebrates. Tet knock-out embryos show overlapping phenotypes with robo2 and are sensitized to reduced levels of slit. Both Robo2 and Slit protein levels were markedly reduced in Tet KO larval brains. Our results establish a role for Tet-dependent 5hmrC in facilitating the translation of modified mRNAs, primarily in developing nerve cells. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Restoration of the Saints (9) (Audio) David Eells - 9/11/22 The Divine Image Destroyed May 4, 2021 - By Christine Beadsworth Below is a portion of this blog page by Christine Beadsworth: The Holy Spirit has been speaking much to me about the forceful drive being perpetuated worldwide to introduce a purported medicine via needle into every human on the planet. I have received a number of dreams bringing revelation and understanding and I feel led to share these things in a series of posts. He started by showing me the whole scenario from God's point of view as He watches His beautiful creation being sabotaged. The visual picture which the Holy Spirit used was a wonderfully crafted palace, surrounded by a high wall. This amazing edifice was guarded day and night from intruders and only the King and those carefully vetted attendants serving him were allowed access. Then one day, a very destructive device was smuggled into the palace by a trusted page boy and the king was unaware that right within the Throne-room, the enemy had positioned one of his henchmen. We can see the same scenario in the positioning of Haman right next to king Xerxes. Oblivious to the danger, king Xerxes handed Haman his signet ring and gave him permission to send out a death decree (Esther 3:8). The human cell nucleus is that walled palace. The human cell is created with a nucleus wall to protect the scroll of DNA within its nucleus. Just like a wall is built around a palace to protect the ruler of a nation, these very important unique documents (our books or DNA scrolls) are guarded from marauders. Nothing is allowed to breach that wall and only trusted messengers are permitted to enter or leave that hallowed place. From within the nucleus, orders are issued by the DNA and carried by the messenger RNA through the nucleus wall to the golgi apparatus, which is a factory making proteins to build and strengthen the body. No other substance can pass through that wall except human mRNA. It is considered trustworthy to carry and deliver the messages issued. I once heard a plant virologist describe mRNA like a shopping trolley. You can load whatever you want in it and it will transport it to the intended destination. Now this works well when the human body is not interfered with. We are fearfully and wonderfully made. MRNA faithfully carries the instructions issued by the unique DNA dwelling in the nucleus citadel. Psa 139:14-16 I will praise You; for I am fearfully and wonderfully made; Your works are marvellous and my soul knows it very well. 15 My bones were not hidden from You when I was made in secret and skillfully formed in the lowest parts of the earth. Psa 16 Your eyes saw my unformed substance, and in Your book (scroll) all the days [of my life] were written (engraved) before ever they took shape, when as yet there was none of them. Now, did you know that every single strand of human DNA is marked with the name of God. “How?” you ask… Because there are sulphide bonds holding together the two strands of DNA and they occur after the 10th pair of nucleotides, again after the 5th pair of nucleotides, then 6 pairs later and then again 5 pairs later. The 10th letter of the Hebrew alphabet is yod. The 5th letter is hey. The 6th letter is vav. Yod, hey, vav, hey spells ‘Yahweh'. I will say it again – God's name is on every human chromosome. You are made in His image and sealed with the Name of your Creator. Every cell in your body is hallmarked! And it is this very Divine hallmark that the enemy desires to obliterate. By injecting loaded messenger RNA into cells, one can sneak fragments of foreign enemy DNA through the carefully guarded nuclear cell walls and unload their contents into the scroll of DNA that God wrote for you. That's like pasting some pages of a counterfeit author's book into the middle of the instruction blueprint God wrote. What is actually happening is that the name of God written into the sulphide bond arrangement in the DNA scroll is being erased. The beautiful scroll engraved by God to create a man in His image is being sabotaged and from that moment of splicing onward, instead of instructions being released from the palace for life and health and security of the body, the inserted DNA loads up the mRNA trolley with instructions for the protein factory in the cell outside the palace to start manufacturing enemy spike proteins. The protein factory just does what it is told. Whatever orders arrive from headquarters are immediately carried out. To put it simply, once the potion is injected into the body, every single citadel guarding scrolls signed with the Name of the Creator within you is highjacked and forced to issue instructions to manufacture weapons of death – which will not only kill you at some point, but also the people around you. It is a cleverly engineered coup on a worldwide scale to throw off the rulership of God over His creation. So who is behind this dastardly plot? What does Psalm 2 say? Psa 2:2-3 The kings of the earth set themselves, and the rulers take counsel together, against the LORD, and against his anointed, saying, 3 Let us break their bands asunder, and cast away their cords from us. The word for ‘band' means ‘bond, halter, restraint'. Is it not the carefully placed sulphide bonds that depict Yahweh's Name which are disrupted and broken asunder by the vaccine contents? The word ‘cord' in Hebrew also means ‘entwined, rope, thick boughs'. Is the DNA not entwined like a rope? Perhaps you can now see the plan of the kings of the earth; the elite, who are banding together and arraying themselves against the Lord. The plan is to highjack His creation, destroy His image, remove His signature and transform the human body into a genetically modified part human/part computer, which can be controlled externally. Sounds like science fiction, but tragically it is the truth. Satan hates all who are made in God's image; every earthen vessel that is intended to become a dwelling place of His Spirit, receiving daily communication from the Throne room of Heaven. For centuries he has been content to defile the bodies and souls of man by luring them into sin of every kind, but, always, his greatest ambition has been to sit in the place intended only for God in the human body. 2 Th 2:4 says that his intention is to ‘sit as God in the temple of God, setting himself forth as if he is God'. Many are waiting for the third temple to be built so that the antichrist can go and sit in it, but THE BODY OF CHRIST IS THE 3RD TEMPLE; a temple not built with hands – and the diabolical deception currently underway is the first step in the rollout of the plan to install the abomination that causes desolation right within the holy place of the 3rd temple! In the holy place, the place where the unique engraved scroll of your Creator is stored in a walled citadel, the enemy has already lifted up his battle cry. How apt is the cry of the psalmist in Psa 74:3-11 Direct Your feet [quickly] to the perpetual ruins and desolations; the foe has devastated and desecrated everything in the sanctuary. 4 In the midst of Your Holy Place Your enemies have roared [with their battle cry]; they set up their own [idol] emblems for signs [of victory]. 5 They seemed like men who lifted up axes upon a thicket of trees to make themselves a record. 6 And then all the carved wood of the Holy Place they broke down with hatchets and hammers. 7 They have set Your sanctuary on fire; they have profaned the dwelling place of Your Name by casting it to the ground. …10 O God, how long is the adversary to scoff and reproach? Is the enemy to blaspheme and revile Your name forever? 11 Why do You hold back Your hand, even Your right hand? Draw it out of Your bosom and consume them [make an end of them]! ‘They have profaned the dwelling place of Your Name' — there is no better description of what is happening worldwide in the human body than these words. And in every nation, believers are being coerced into taking the supposed health inducing jab. Is this not causing the ‘great falling away' described in 2 Th 2:3? The totality of the scheme is to leave the 3rd temple desolate, destroyed, overtaken and subjugated to an ancient enemy who always coveted God's throne and the worship of God's Bride. Apostasia, the Greek for ‘falling away', means ‘defection from truth' and comes from Strongs G647, which means ‘to separate, the writing of divorcement'. How significant that a fragment of DNA writing is what separates or breaks asunder the record of God's Name in the human DNA! Now obviously the smuggling in of the death warrant to the guarded throne room involves deception and subterfuge. No-one would allow such an intrusion if it was advertised by its true content. The coup is enacted under the guise of delivery of a basket of wishes for health and happiness. (Pity, there is a poisoned apple in the fruit bowl!) Revelation chapter 18 speaks of the judgement that is incurred by those who carry out this deception. As you read the selected verse, remember that the Greek word translated ‘sorceries' is pharmakeia, the word from which we get ‘pharmacy, dispenser of medicine', Rev 18:23b …For your merchants were the great ones of the earth; for by your sorceries all nations were deceived. So it is pharmaceutical deceptions which are employed to pull the wool over the eyes of all the nations. 2 Th 2:11 says a ‘strong delusion' is released so that people believe a lie. The Greek for ‘delusion' comes from a root word meaning ‘deceiver or imposter'. So the recurring theme is deception which brings destruction. No surprise that pharmakeia also means ‘witchcraft', and comes from a root word meaning ‘drug, poisoner'. Poison is intended to induce the death of the victim. The Word tells us that the life is in the blood. It is surely no coincidence that the foreign spike proteins – which the human body is induced to produce after it is highjacked, trigger blood clots; which in turn cause fatal heart attacks and strokes. It is satan who seeks to steal, kill and destroy. Jesus came that you may have life and have it abundantly. Satan desires to remove God's image and replace it with his image (Rev 14:9). He plans to remove God's name and replace it with his name (Rev 14:11). Ask yourself who else could be behind the erasing of God's Name in your DNA scroll. Beloved, God says His people perish for lack of knowledge. Many pastors and shepherds worldwide are urging their congregations to receive the phamakeia they offer. May the sheep wake up and see the edge of the precipice before they plunge over it. I would urge you to guard and keep your temple holy unto the Lord. Do not allow it to be breached. Cherish His Name encoded into the scroll of life within you and take refuge under the shadow of His wings. Do not run to Egypt or Babylon for help. Do all you can to boost your divinely built immune system… and do not allow yourself to be deceived. Be a lover of Truth. Seek truth. Go after it. 2 Th 2 is clear that it is those who do not love truth who will fall prey to the strong delusion wrapping its fingers around the globe. Do not succumb to those who call evil good and scheme to overthrow and render your holy place desolate. You will pay for it with your life. Rather entrust yourself to Him Who is the Truth, the Life and the way. Choose life that you and your children may live! 2Co 6:16-18 And what agreement does a temple of God have with idols? For you are the temple of the living God, as God has said, “I will dwell in them and walk among them; and I will be their God, and they shall be My people.” 17 Therefore come out from among them and be separated, says the Lord, and DO NOT TOUCH THE UNCLEAN THING. And I will receive you 18 and I will be a Father to you, and you shall be My sons and daughters, says the Lord Almighty. Is This Why They Want to Change our DNA? Transcript of Rumble Video: Uncensored Sam - 9/9/21 God's true name is recorded within our DNA. So, just let me go ahead and explain. Our chains of DNA contain four nucleotide-based pairs called Adenine, Guanine, Thiamine, and Cytosine. And then there's a unit within the DNA strand called a sulfuric bridge. This sulfuric bridge holds our entire DNA strand together. It only appears after every ten nucleic acids have been laid down, and then after every five nucleic acids, then after every six, and then again, after every five nucleic acids. So, we get this repeating numerical value of 10, 5, 6, 5 within our DNA strand. Well, it turns out the Biblical name for God, YHWH, contains the same numerical value as our DNA strand. Yod He Vav He equals ten, five, six, five. What's even more interesting is that if you take the Hebrew characters of the name of YHWH and place it on its side, you get the image of a human being. Part three of this video series suggests that DNA is a language. Many people were wondering what “god" made the language of DNA. Researchers at Harvard University announced today that they have found what appears to be a message from God written inside the human genome. In a little-explored section of non-coding DNA, a team of top geneticists discovered a 22-word snippet of ancient Aramaic in which God confirms His existence and His role in creating life on Earth. “We knew the patterns weren't naturally occurring,” explains Charles Watson, the lead scientist on the project, “but we couldn't come up with any convincing explanation for them. On a whim, we started cross-referencing the patterns with language databases,” he explains, “and we were shocked to find that the patterns corresponded to ancient Aramaic.” Stunned by its discovery, the team contacted language experts familiar with Aramaic – the language Jesus Christ spoke in daily life. Entirely decoded, the message reads: "Hello my children, This is Yahweh, the One True Lord. You have found creation's secret. Now share it peacefully with the world." Go tell the world Who is the true God and Creator of all! DNA: Good and Evil Seed Kenneth (David's notes in red) Here below is an amazing testimony of a 16-year-old young lady from South Africa. It is an astonishing confirmation of the battle of good and evil and how it lives within us from birth. It is again a supernatural confirmation of the truths found in the Bible from Genesis through Revelation. It is a confirmation of the Daniel 2:43 problem where "they" mingle themselves with the seed of man. GLORY TO JESUS. I pray this both edifies and blesses you with the reality of how our science, indeed God's science, is found in our Holy Bible. DNA Structure ~ A Word from I AM to His True Set-Apart Bride in these End Times - July 9, 2013 at 6:23am ... given through His beloved daughter, Sarah (16 years old) on 5th July 2013 ... Please NOTE that this Word from the mouth of Yahushua haMashiach is not specific to South Africa only, but is for His Set-apart Bride collectively. Yeshua stood next to me dressed in white light, He stretched out His pierced hand and said, "Come with Me, My Sarah Princess, My Deborah warrior"... It was as if we were eagles, flying over South Africa. He showed me different things in the country. I saw fires in many places. Yeshua smiled and said, "It's My fire; My Spirit is fanning the flame in the hearts of those who choose to walk the road less traveled, in those who choose to let go of the passions of the flesh, I am busy in this country you call home, My love. There are many things to come as you know". I see a big statue of Nelson Mandela with a rainbow around it. Yeshua looked at it and turned His face... "Sarah, look at the way people make an idol out of man - REPENT THEREOF". Then He said, "The nation's pride will come to a fall". I saw the statue slowly diminishing on the inside until there was nothing left on the inside of the statue, but it was still standing. I saw people crying, lots of people stood in groups and cried. "Tell those who so humbly and faithfully stand in the gap for this nation, pray and plead for this nation that they will soon start to see the fruit of their supplication". While He said that, I saw many people praying and repenting for the things in this country. (This should be done in whatever nation you are. The fruit of that worldly nation will be the elect of God.) "My love, remember I said in My Book, I put before you light and darkness, blessing and curse, and you have the choice; which one do you choose? You are between two Kingdoms, My love. At the same time I am busy, the wicked one is also busy... I AM shining My glorious light through the words of My prophets and messengers and those who give ear will receive blessing, the blessing of knowing the truth and having it make you free. I want to speak to you about what I am busy with so that My people can catch up with My heartbeat, so that they can dance in the rhythm of My ways, My truths, My desires... "I am busy gathering My bride into the ark where she will be safe. It is only those who have cleansed their DNA, those who have pure blood that can enter. Sarah, tell My people to give attention to what I will tell you now; it is very important, it is a matter of purity and harlotry, salvation and deception, luke-warmness and fire... Give ear!" The next moment, it was as if I was inside of a body and I see conception taking place, the sperm cell and the egg cell colliding, merging and 'becoming' a baby. I see the seed in very much detail; there were these little things like white vessels that looked like trees inside the seed (family trees, our genetic inheritance from our parents in the world). At the same time, while I was looking at that, I also saw that the seed is like a book and there are many, many words inside that very tiny seed. (Words pass along to our physical seed, cursing or blessing, by our nature). (The seed of the spiritual man is like a book also, the Bible. Our meditation on the Word empowers and releases the spiritual man to control the physical man and the demons.) (Kenneth's comment: The Psalmist wrote: Thine eyes did see my substance, yet being unperfect (unformed); and in thy book all my members were written, which in continuance were fashioned, when as yet there was none of them. (Psalm 139:16) Yeshua started to speak to me about the DNA once again... "My love, do you see? Look at it; it's beautiful... out of these little tiny seeds a human grows, inside of these little seeds I put everything for a baby to grow; it is perfect (it was very, very special to see Yeshua so excited about how perfect and amazing and AWESOME He made the human body, soul and spirit). Look inside the seed, do you see the written things? It is a code, it's a DNA code; it's far above what any human can understand. That code, My love, determines who that baby will be, that code will form its character, personality, likes and dislikes. It forms the body and it forms the soul, but not the spirit. The spirit is born of Spirit, My Spirit. In your spirit you inherit My DNA when you are saved, but this DNA, this seed and inheritance, is not saved yet. Sarah, inside of that seed is blessing and curse, sin and righteousness as an inheritance from your fathers. (For this reason mad scientists want to recreate the DNA after their own liking by perverting the food, water, and air and by va/cci/nes. This way they can create the body of the beast.) "This DNA is very, very important. Inside of the DNA code, there are supposed to be key essentials so that your body and soul can function the way I purposed them to. These seeds in the DNA are love proteins, and when you are born, the seed will sprout if it is exposed to the right elements. The mother and father are to nurture, comfort, affirm, accept and love this gift from Me and the result will be gender identity and spiritual identity, a healthy and whole soul and body. But now the babies are being exposed to trauma - even at birth - with the way this precious child comes into this world. The children are vulnerable to whatever the parents expose them to, even in the womb, and it has a great effect on them. (Speak blessing over the unborn.) It is the parents' work to build the child's identity through teaching them to find their identity in Me, but they are exposed to the trauma of rejection (opening them up to demonic bondage)... "This DNA speaks all the time. It speaks of every word written inside of it. You can hear it and I can hear it too; you hear it in your mind every day. Sarah, your inherited DNA affects your soul and body in a great, great way. Let Me explain to you how it affects you in a physical and mental way. Your soul area is your mind, will, emotions, desires. The seed in your DNA grows like trees throughout your soul. For example, if you inherited a seed of rejection, that seed will carry the hurts and pain of the generations before you. (We have seen this to be true. Many don't know why they are the way they are, always lusting for acceptance and admiration from others. Rejecting any correction or person that knows about them.) That seed is in you and when you experience any kind of trauma, trauma at birth, as a child, or any kind of trauma, the seed sprouts and a stronghold forms inside your soul. (Any perceived threat to the ego puts them in survival mode.) A stronghold forms to suppress the pain. The stronghold is always rooted in pride and fear keeps it in place. These trees are rebellion against Me. This tree bears ungodly fruit in your soul like perfectionism, judgment, fear, pride ... (Rejection is bearing much fruit in these days to separate the tares from the wheat but repentance is possible through faith in Jesus' sacrifice. These two seeds are manifested through one's actions and words. {Mat.13:37} And he answered and said, He that soweth the good seed is the Son of man; {38} and the field is the world; and the good seed, these are the sons of the kingdom; and the tares are the sons of the evil [one]; {39} and the enemy that sowed them is the devil: and the harvest is the end of the world; and the reapers are angels. {40} As therefore the tares are gathered up and burned with fire; so shall it be in the end of the world. {41} The Son of man shall send forth his angels, and they shall gather out of his kingdom all things that cause stumbling, and them that do iniquity, {42} and shall cast them into the furnace of fire: there shall be the weeping and the gnashing of teeth. {43} Then shall the righteous shine forth as the sun in the kingdom of their Father. He that hath ears, let him hear. "Because I love you so dearly and because you struggled so much as a little girl to understand why 'this Father of love' would create imperfect, disabled little babies, I will show you why this happens. "This seed of rejection, for example, can affect your body in many ways; sometimes the sickness manifests in a later stage because of trauma and other times because of open doors in the mother and father. Because of generational curses, spirits latch onto the DNA and the baby can be born with a defect, a disease or disabled. It is part of the curse that came upon man at the fall. (However, a believing parent sanctifies the child through faith, as Paul said in 1 Corinthians 7, and can deliver the child from the curse of defect and disease.) Sarah, there are many things I want to teach you about the DNA. My people have a lack of knowledge! I also want to teach you about the DNA structure: It is an order. There are two orders: the one comes out of hell and the other out of Who I AM! Out of hell comes The Order of Baal and man plays the harlot with it, and I will call My order The Order of I AM! This is the structure in your DNA. "Inside The Order of Baal is the structure, the nature and the seed of lucifer. Curse is a result of it, most sicknesses are a result of it, spiritual death is a result of it, poverty is a result of it and destruction is a result of it. I have spoken to you a lot about the pure bride and about what it means to be the pure bride. The pure bride has My DNA, she has My structure, My order, My nature and My seed in her. Blessing is a result of it, life is a result of it, prosperity is a result of it, holiness and righteousness are a result of it. "My bride has I AM flowing through her veins, while the harlot bride, who has not cleansed her DNA, has hell operating through her … a mixed seed. My people are playing harlot because they have the order and the structure of Baal in them -that is why they are double-minded, that is why they are still sick. Even though by My stripes you were healed, they have remained still sinful, unholy and unrighteous, but they call themselves Christians. I tell you the word Christian is (misused and is) reserved for those who are lukewarm. You are either My bride, holy, pure and righteous, building your spirit house upon the Rock of Ages, living in My Kingdom, or you are a 'Christian,' lukewarm, so-called saved but deceived, so-called good but led astray without even knowing it. This 'Christian' is part of the harlot; she is in fact worse than the sinner because she is the same as the sinner in heart, but she thinks she is good. "My people, if you want to go into the ark like Noah, you have to cleanse your DNA through applying My blood through repentance, through petitioning in My heavenly courtroom. Remember, your spirit can be holy and righteous and you can think you are on the right road because of it. But if you do not take the next step through cleansing your DNA and working on your soul dimension, you are divided within yourself - in your spirit, on fire, and in your soul, cold, and therefore you are mixed, mixed and lukewarm. My bride is not mixed, she is single-minded and in unity with Me, one in soul and spirit. (She is one with the Word in her heart and obedience to it.) "I want My people to break down the altar, the order and the structure of Baal in your blood (DNA) that your forefathers have cast up. Like Gideon had to break down the altar of Baal. ("Come out of her My people".) {Jdg.6:25} ... Tear down the altar of Baal that your father has, and cut down the wooden image that is beside it; {26} and build an altar, to the LORD your God on top of this rock laid in proper order [proper arrangement]. I was petitioning and repenting for my DNA and while I did that I saw a vision of inside of my body, I saw the many blood vessels, and Yeshua took me inside of my blood where He showed me how my DNA looks in the spirit. I saw the structure of the DNA and I saw two doors inside of my DNA (blood). There was a black door and a golden door. The golden door was closed and the black door was open. Out of the black door the DNA structure flowed; on the black door was written "Order of Baal/Curse" and on the golden door was written "I AM/Blessing" (which is filled with the FULLNESS of ABBA's character, attributes, nature, in the name of I AM is the fullness of who He is). There were things written on the black structure that flowed out of the black door. I recognized it as pride and rebellion against I AM (everything YHVH stands for), the nature of hasatan. So I started to pray for I AM's light to shine in my DNA and I just started to repent of generational sin as Ruach haKodesh revealed it to me. He went really deep and I carried on for hours. While I was busy repenting, I saw the structure going back into the black door, like it was being reversed. I literally saw Yeshua inside of my blood; He closed the black door and the door and the structure disappeared (shattered the order of Baal and curses). It is as if the black door was a gateway of hell. Yeshua said, "Each and every human has these two doors in their blood; hell operates through the black door through pride, rebellion and curses - it is his nature flowing out of it; while I AM and blessing flows through the way, the truth and the life. (Jesus comes through the spirit man and Satan and his minions through the inherited flesh and its lusts.) My people, you are in a DNA war. Awaken and see that the battle you are in is a blood battle; the enemy is out to defile your blood. Break down The Order of Baal inside of you through repentance and petitioning. Your DNA is who you are; it is the core of you. I want who you are to be a vein, a vessel for I AM, for I AM to flow through you and be an altar of worship, singing holy (set-apart), holy (set-apart), holy (set-apart), holy (set-apart)!" While He said that, the golden door flung open and a white structure flowed out, with golden and silver writings on it. I AM's character and nature was inside of it - humility, holiness(set-apartness), love, gentleness, etc. "Sarah, My love, this is the message for this hour. Teach My people how to sanctify their DNA because this is what My bride looks like". I see what flows out of that door is His seed [love and righteousness]. If it is the black door, it is hasatan's seed [pride and rebellion]. Father's seed births purity and holiness (set-apartness) and results in a set-apart virgin bride, whereas satan's seed births pride, harlotry, idolatry - it is mixed seed - and this makes you a harlot bride that can give birth to Nephilim babies. (Meaning dark spiritual giants, a mixture of flesh and demons; people who are big in the world because they are of the world, and they are small before God, like famous false Christians.) Yeshua showed me that the written things on our DNA become what our mind meditates upon. (We can meditate on flesh or spirit and bear the fruit thereof. {Isa.26:3} Thou wilt keep [him] in perfect peace, [whose] mind [is] stayed [on thee]; because he trusteth in thee. Rom 12:2 And be not fashioned according to this world: but be ye transformed by the renewing of your mind, that ye may prove what is the good and acceptable and perfect will of God.) Your mind literally records whatever is inside the DNA. For example, when there is generational racism seed in your DNA, you have a judgmental, prideful, racist stronghold in your mind (of course you don't acknowledge it as that). Because you inherit the seed from your fathers, it hides in you and when trauma occurs it explodes like a bomb in your soul. It is the same with homosexuality; if there is a seed of rejection, to which a spirit latches, that attacks and breaks down your identity physically and because there is no love inside of that seed, it can very easily manifest in one becoming homosexual. The homosexual spirit is the stronghold that the structure of your soul puts up to defend itself, but it comes out of a seed of rejection, out of the pits of hell. (Many other spirits use the spirit of rejection as a doorkeeper to let them in: rebellion, anger, frustration, domineering, Jezebel, witchcraft, faction, drunkenness, drug addiction, self-seeking, etc.) We are in a spiritual battle that manifests in the natural and the war is already won, if we would just start to apply the Blood of the Lamb, we would start to taste victory and freedom. Our weapon is the BLOOD OF THE LAMB (which carries Yeshua's DNA) because it is the fullness of I AM's LOVE, poured out for our salvation, redemption, deliverance, healing, freedom... REPENT, so that you can be called righteous like Noah was righteous in all his generations! See also Deliverance from Rejection and Its Fear UBM site link: dna Restoration of the Body Tommy Hicks - 7/25/61 (David's notes in red) The following is an excerpt of a stunning vision given to American preacher Tommy Hicks, who was a major figure in the powerful 1954 Argentina Revival. VISION OF THE BODY OF CHRIST AND THE END-TIME MINISTRIES “…In the book of Acts we read, "In the last days", God said, "I will pour out my Spirit upon all flesh". I wonder if we realized what he meant when God said, "I will pour out my Spirit upon all flesh". I do not think I fully realized nor could I understand the fullness of it, and then I read from the book of Joel: "Be glad then, ye children of Zion, and rejoice in the Lord your God: for he hath given you the former rain moderately, and he will cause to come down for you the rain, the former rain, and the latter rain -" (Joel 2:23). It is not only going to be the rain, the former rain and the latter rain, but he is going to give to his people in these last days a double portion of the power of God! As the vision appeared to me after I was asleep, I suddenly found myself in a great high distance. Where I was, I do not know. But I was looking down upon the earth. Suddenly the whole earth came into my view. Every nation, every kindred, every tongue came before my sight from the east and the west, the north and the south. I recognized every country and many cities that I had been in, and I was almost in fear and trembling as I beheld the great sight before me: and at that moment when the world came into view, it began to lightning and thunder. As the lightning flashed over the face of the earth, my eyes went downward and I was facing the north. Suddenly I beheld what looked like a great giant, and as I stared and looked at it, I was almost bewildered by the sight. It was so gigantic and so great. His feet seemed to reach to the North Pole and his head to the south. Its arms were stretched from sea to sea. I could not even begin to understand whether this was a mountain or a giant, but as I watched, I suddenly beheld a great giant. I could see his head was struggling for life. He wanted to live, but his body was covered with debris from head to foot, and at times this great giant would move his body and act as though it would even rise up at times. And when it did, thousands of little creatures seemed to run away. Hideous creatures would run away from this giant, and when he would become calm, they would come back. (These are the demons that are keeping God's people in bondage.) All of a sudden this great giant lifted his hand towards heaven, and then it lifted its other hand, and when it did these creatures by the thousands seemed to flee away from this giant and go into the darkness of the night. Slowly this great giant began to rise and as he did, his head and hands went into the clouds. As he rose to his feet he seemed to have cleansed himself from the debris and filth that was upon him, and he began to raise his hands into the heavens as though praising the Lord, and as he raised his hands, they went even unto the clouds. (Representing the great revival through Jesus in the Man-child reformers.) Suddenly, every cloud became silver, the most beautiful silver I have ever known. As I watched this phenomenon it was so great I could not even begin to understand what it all meant. I was so stirred as I watched it, and I cried unto the Lord and I said, "Oh Lord, what is the meaning of this". and I felt as if I was actually in the Spirit and I could feel the presence of the Lord even as I was asleep. And from those clouds suddenly there came great drops of liquid light raining down upon this mighty giant, and slowly, slowly, this giant began to melt, began to sink itself in the very earth itself, and as he melted, his whole form seemed to have melted upon the face of the earth, and this great rain began to come down. Liquid drops of light began to flood the very earth itself and as I watched this giant that seemed to melt, suddenly it became millions of people over the face of the earth. As I beheld the sight before me, people stood up all over the world! They were lifting their hands and they were praising the Lord. At that very moment there came a great thunder that seemed to roar from the heavens. I turned my eyes toward the heavens and suddenly I saw a figure in white, in glistening white - the most glorious thing that I have ever seen in my entire life. I did not see the face, but somehow I knew it was the Lord Jesus Christ, and he stretched forth his hand, and as he did, he would stretch it forth to one, and to another, and to another. And as he stretched forth his hand upon the nations and the people of the world - men and women - as he pointed toward them, this liquid light seemed to flow from his hands into them, and a mighty anointing of God came upon them, and those people began to go forth in the name of the Lord. I do not know how long I watched it. It seemed it went into days and weeks and months. And I beheld this Christ as he continued to stretch forth his hand; but there was a tragedy. There were many people as he stretched forth his hand that refused the anointing of God and the call of God. I saw men and women that I knew. People that I felt would certainly receive the call of God. But as he stretched forth his hand toward this one and toward that one, they simply bowed their head and began to back away. And each of those that seemed to bow down and back away, seemed to go into darkness. Blackness seemed to swallow them everywhere. (Their sin was more valuable to them than the anointing.) I was bewildered as I watched it, but these people that he had anointed, hundreds of thousands of people all over the world, in Africa, England, Russia, China, America, all over the world, the anointing of God was upon these people as they went forward in the name of the Lord. I saw these men and women as they went forth. They were ditch diggers, they were washer women, they were rich men, and they were poor men. I saw people who were bound with paralysis and sickness and blindness and deafness. As the Lord stretched forth to give them this anointing, they became well, they became healed, and they went forth! And this is the miracle of it - this is the glorious miracle of it - those people would stretch forth their hands exactly as the Lord did, and it seemed as if there was this same liquid fire in their hands. As they stretched forth their hands they said, "According to my word, be thou made whole". As these people continued in this mighty end-time ministry, I did not fully realize what it was, and I looked to the Lord and said, "What is the meaning of this?" And he said, "This is that which I will do in the last days. I will restore all that the cankerworm, the palmerworm, the caterpillar - I will restore all that they have destroyed. This, my people, in the end times will go forth. As a mighty army shall they sweep over the face of the earth”. (Representing the great restoration.) As I was at this great height, I could behold the whole world. I watched these people as they were going to and fro over the face of the earth. Suddenly there was a man in Africa and in a moment he was transported by the Spirit of God, and perhaps he was in Russia, or China or America or some other place, and vice versa. All over the world these people went, and they came through fire, and through pestilence, and through famine. Neither fire nor persecution, nothing seemed to stop them. Angry mobs came to them with swords and with guns. And like Jesus, they passed through the multitudes and they could not find them, but they went forth in the name of the Lord, and everywhere they stretched forth their hands, the sick were healed, the blind eyes were opened. There was not a long prayer, and after I had reviewed the vision many times in my mind, and I thought about it many times, I realized that I never saw a church, and I never saw or heard a denomination, but these people were going in the name of the Lord of Hosts. Hallelujah! As they marched forth in everything they did as the ministry of Christ in the end times, these people were ministering to the multitudes over the face of the earth. Tens of thousands, even millions seemed to come to the Lord Jesus Christ as these people stood forth and gave the message of the kingdom, of the coming kingdom, in this last hour. It was so glorious, but it seems as though there were those that rebelled, and they would become angry and they tried to attack those workers that were giving the message. (As it was with the Pharisees and Sadducees.) God is going to give the world a demonstration in this last hour as the world has never known. These men and women are of all walks of life, degrees will mean nothing. I saw these workers as they were going over the face of the earth. When one would stumble and fall, another would come and pick him up. There were no "big I's" and "little you's", but every mountain was brought low and every valley was exalted, and they seemed to have one thing in common - there was a divine love, a divine love that seemed to flow forth from these people as they worked together, and as they lived together. It was the most glorious sight that I have ever known. Jesus Christ was the theme of their life. They continued and it seemed the days went by as I stood and beheld this sight. I could only cry, and sometimes I laughed. It was so wonderful as these people went throughout the face of the whole earth, bringing forth in this last end time. As I watched from the very heaven itself, there were times when great deluges of this liquid light seemed to fall upon great congregations, and that congregation would lift up their hands and seemingly praise God for hours and even days as the Spirit of God came upon them. God said, "I will pour my Spirit upon all flesh", and that is exactly this thing. And to every man and every woman that received this power, and the anointing of God, the miracles of God, there was no ending to it…" UBM Angels Give Some Details of the Coming Great Revival Excerpt from Ministering Angels Through UBM #3 David asked, “What can you tell us about the supernatural methods to get the gospel out and heal, deliver and save?” The angel Baruch said, "The methods of man will not be employed to reach the peoples of the earth. (In the days that are coming.) The methods are all of the spirit realm and will be administered by the angels who are going to distribute the gifts to the saints. (Meaning, the sanctified ones) These include gifts of translation from place to place, language, healing, laying on of hands to impart to others their needs and what they're lacking and to replicate the gifts by passing them on to others whom the angels will point out. Supernatural downloads of wisdom and knowledge will be received for specific situations.” David asked, “What about deliverances?” Baruch said, “The enemy will be on the run during this time. Deliverances will be instantaneous with no resistance on their part. (Many deliverances are this way now if there is cooperation on the part of the victim in repentance and faith.) They will no longer be able to hide in flesh because of the light of revival and the fire of truth that will sweep the elect of the globe.” (Eve said, “Meaning: Demons will be fleeing left and right out of people as the true fire of the Holy Spirit fills each one and searches the depths of each individual. There won't be any place left for them to hide in the elect of God.") David asked, “Will there be mass healings and deliverances? Baruch said, “ Yes. These will all take place on the largest scale in human history.” (Eve said, "Meaning: Masses of people will supernaturally be delivered and healed all at once for times sake because the need is so great and the darkness so pervasive.") Then the angel Shemuel said, "A great move of God is coming upon the younger generations. (i.e. The millennials - Generation Z) There is a mildew and rottenness that has been cast upon this crop by satan; a perpetual darkness, so that the Son has not shown upon them. They languish and rot in the field and their fruit is poisoned. But the Son is coming to shine down upon them and he will burn up all the disease and mildew of their lives and the heat of His fire will burn through them and cleanse and restore them to the purpose they were created for. There has never been a revival like this that will sweep the whole earth. This will be entirely an act of God; supernatural and undeniable. He will not forsake the youth of this final generation.' Our Promised DNA Restoration Excerpt from Ministering Angels Through UBM #3 David asked, “What does the coming restoration involve personally? 30 years younger?” The angel Jeruel answered, “Restoration on a DNA cellular level. Faith and power will be imputed to receive healing and restoration. It will be complete restoration not partial. The first fruits are first. They will be the trail blazers. There will also be a mighty supernatural outpouring of spiritual restoration of closeness to God through His Holy Spirit.” Then David asked, “When will the Lord restore our teeth?” The angel Baruch said, “When the DNA restoration takes place, teeth will be restored as well.” Our Corporate Birthday Party Isaac Payne - 8/19/22 (David's notes in red) In this dream I was hosting a birthday party at my doublewide in Florida. (I think Florida is symbolic due to it being called the sunshine state. Also, I think the doublewide represents John 1:16 For of his fullness we all received, and grace for grace. Double grace hence doublewide.) The walls of the doublewide were sky blue and pretty much everything in the doublewide was blue. (Blue represents heavenly.) As the birthday party began, we welcomed many people inside. What was odd was that it wasn't anyone's birthday in particular, but actually seemed like a shared birthday party. (The corporate birthing of Jesus in the Man-child reformers and then the choosing of the Bride.) I looked around and saw Missy Pollock and her husband Merle at the birthday party sitting at the dining room table. They looked very happy and I remember thinking Merle is a really fit guy and in good shape and Missy too. (This is the timing of the DNA restoration.) I saw my Uncle Ronnie come to the party also. (Ronnie means ruler, advice, decision, bringer of victory.) (Representing the Father.) Also, David Eells (Representing the Man-child David's.) was there at the house for the birthday party as well. I continued to look around and also saw my cousins Josh and Jake. (Joshua means God is Deliverance and Jacob (Jacob represents Israel as a type of the Church.) (Ronnie, Josh, and Jake are my actual family members on my dads side in real life.) I think this points to spiritual Israel since Jacob was renamed Israel. Romans 9:6 But it is not as though the word of God has come to nought, for they are not all Israel, that are of Israel. But also he took the birthright from Esau. I believe we have been given the birthright from Christ as we are the 42nd generation and have overcome the old man represented by Esau. 2 Co. 1:20 For however many so ever be the promises of God, in him is the yea: wherefore also through him is the Amen, unto the glory of God through us. Then I woke up. (Also, I believe this is confirmation for the DNA regeneration that we were told we would receive.) (There wasn't one feeble one among them when they went out into the wilderness. Moses' eye was not dimmed nor his natural force abated.) The Great Restoration David Eells The Lord reveals that there will be a restoration of His people's lives in an outpouring of the Spirit after the Northern Army, as a type of the faction in the government and in the Church, is defeated at the spiritual Red Sea. This is primarily a restoration to the Bride, as a first-fruits, and later through the Bride to the Church. The Lord has showed us that this Northern Army attack symbolizes the ongoing D.S. attack on the U.S. using Pestilence, Sword, Famine, and Fire, which is listed in scriptures many times in Babylon's war against the apostate leadership, typed as Jerusalem, and God's apostate people... The Northern Army of Assyria tried to conquer righteous Jerusalem, the Bride. They had already conquered the apostate northern tribes, which faction and apostates have done, because these conquered ones are not the Bride, who escaped. Here also is mentioned the restoration of the years this enemy had plundered from God's people. Joel 2:20-27 but I will remove far off from you the northern army, and will drive it into a land barren and desolate, its forepart into the eastern sea, and its hinder part into the western sea; and its stench shall come up, and its ill savor shall come up, because it hath done great things. 21 Fear not, O land, be glad and rejoice; for Jehovah hath done great things. 22 Be not afraid, ye beasts of the field; for the pastures of the wilderness do spring, for the tree beareth its fruit, the fig-tree and the vine do yield their strength. 23 Be glad then, ye children of Zion, and rejoice in Jehovah your God; for he giveth you the former rain in just measure, and he causeth to come down for you the rain, the former rain and the latter rain, in the first month. 24 And the floors shall be full of wheat, and the vats shall overflow with new wine and oil. 25 And I will restore to you the years that the locust hath eaten, the canker-worm, and the caterpillar, and the palmer-worm, my great army which I sent among you. 26 And ye shall eat in plenty and be satisfied, and shall praise the name of Jehovah your God, that hath dealt wondrously with you; and my people shall never be put to shame. 27 And ye shall know that I am in the midst of Israel, and that I am Jehovah your God, and there is none else; and my people shall never be put to shame. I believe this restoration incorporates the power of the Spirit, health, youth, prosperity, doctrine, fruit, gifts, authority, and a general deliverance from all of the curse that Jesus paid for. Gal 3:13 Christ redeemed us from the curse of the law, having become a curse for us; for it is written, Cursed is every one that hangeth on a tree. This restoration will begin with the Bride who will spread this gospel to the true Church of the called out ones. Psa 103:1-5 A Psalm of David. Bless Jehovah, O my soul; And all that is within me, bless his holy name. 2 Bless Jehovah, O my soul, And forget not all his benefits: 3 Who forgiveth all thine iniquities; Who healeth all thy diseases; 4 Who redeemeth thy life from destruction; Who crowneth thee with lovingkindness and tender mercies; 5 Who satisfieth thy desire with good things, So that thy youth is renewed like the eagle. (Eagles, like all other birds, molt. They molt four times before reaching adulthood. Once they achieve their final "adult" plumage, it is likely that Bald Eagles molt their flight feathers just about every year. This represents new clothing which helps it overcome the gravity of the world.) Rom 13:14 But put ye on the Lord Jesus Christ, and make not provision for the flesh, to fulfil the lusts thereof. Job 33:25 His flesh shall be fresher than a child's; He returneth to the days of his youth. God's people coming out of Egypt at the time of the Red Sea received their youthful restoration. Psa 105:37 And he brought them forth with silver and gold; And there was not one feeble person among his tribes. Deu 34:7 And Moses was a hundred and twenty years old when he died: his eye was not dim, nor his natural force abated. Neh 9:21 Yea, forty years didst thou sustain them in the wilderness, and they lacked nothing; their clothes waxed not old, and their feet swelled not. 2Co 5:17 Wherefore if any man is in Christ, he is a new creature: the old things are passed away; behold, they are become new. Abiding in the mind of Christ, the Lions head, will bring about this new creation man. Psa 132:13-18 For Jehovah hath chosen Zion (the Bride); He hath desired it for his habitation. 14 This is my resting-place for ever: Here will I dwell; for I have desired it. 15 I will abundantly bless her provision: I will satisfy her poor with bread. 16 Her priests also will I clothe with salvation; And her saints shall shout aloud for joy. 17 There will I make the horn of David to bud: I have ordained a lamp for mine anointed. 18 His enemies will I clothe with shame; But upon himself shall his crown flourish. Psa 133:3 Like the dew of Hermon, That cometh down upon the mountains of Zion: For there Jehovah commanded the blessing, Even life for evermore. Act 3:19-21 Repent ye therefore, and turn again, that your sins may be blotted out, that so there may come seasons of refreshing from the presence of the Lord; 20 and that he may send the Christ who hath been appointed for you, even Jesus: 21 whom the heaven must receive until the times of restoration of all things, whereof God spake by the mouth of his holy prophets that have been from of old. Jesus will first come manifested in the Man-child reformation ministry to restore all that was stolen from God's people just as He did in His first body except on a much larger scale. Hos 6:1-3 Come, and let us return unto Jehovah; for he hath torn, and he will heal us; he hath smitten, and he will bind us up. 2 After two days will he revive us: on the third day he will raise us up, and we shall live before him. 3 And let us know, let us follow on to know Jehovah: his going forth is sure as the morning; and he will come unto us as the rain, as the latter rain that watereth the earth. 1Pe 5:10 And the God of all grace, who called you unto his eternal glory in Christ, after that ye have suffered a little while, shall himself perfect, establish, strengthen you. Psa 71:20-21 Thou, who hast showed us many and sore troubles, Wilt quicken (meaning: Make alive) us again, And wilt bring us up again from the depths of the earth. 21 Increase thou my greatness, And turn again and comfort me. Jer 30:1-3 The word that came to Jeremiah from Jehovah, saying, 2 Thus speaketh Jehovah, the God of Israel, saying, Write thee all the words that I have spoken unto thee in a book. 3 For, lo, the days come, saith Jehovah, that I will turn again the captivity of my people Israel and Judah, saith Jehovah; and I will cause them to return to the land that I gave to their fathers, and they shall possess it. This speaks of the Church coming out of captivity to the beast kingdom to return to the Land of milk and honey; the land of our spiritual forefathers in the Gospels and Book of Acts. We are going to have our own Book of Acts but greater in scope and intensity. Isa 40:31 but they that wait for Jehovah shall renew their strength; they shall mount up with wings as eagles; they shall run, and not be weary; they shall walk, and not faint. What energy Father will put in His people to bring in the harvest. Jer 29:11-14 For I know the thoughts that I think toward you, saith Jehovah, thoughts of peace, and not of evil, to give you hope in your latter end. 12 And ye shall call upon me, and ye shall go and pray unto me, and I will hearken unto you. 13 And ye shall seek me, and find me, when ye shall search for me with all your heart. 14 And I will be found of you, saith Jehovah, and I will turn again your captivity, and I will gather you from all the nations, and from all the places whither I have driven you, saith Jehovah; and I will bring you again unto the place whence I caused you to be carried away captive. Back to the Bride we started from. Joh 3:29 He that hath the bride is the bridegroom: but the friend of the bridegroom, that standeth and heareth him, rejoiceth greatly because of the bridegroom's voice: this my joy therefore is made full. Isa 60:10-22 And foreigners shall build up thy walls, and their kings shall minister unto thee: for in my wrath I smote thee, but in my favor have I had mercy on thee. 11 Thy gates also shall be open continually; they shall not be shut day nor night; that men may bring unto thee the wealth of the nations, and their kings led captive. 12 For that nation and kingdom that will not serve thee shall perish; yea, those nations shall be utterly wasted. 13 The glory of Lebanon shall come unto thee, the fir-tree, the pine, and the box-tree together, to beautify the place of my sanctuary; and I will make the place of my feet glorious. 14 And the sons of them that afflicted thee shall come bending unto thee; and all they that despised thee shall bow themselves down at the soles of thy feet; and they shall call thee The city of Jehovah, The Zion of the Holy One of Israel. 15 Whereas thou hast been forsaken and hated, so that no man passed through thee, I will make thee an eternal excellency, a joy of many generations. 16 Thou shalt also suck the milk of the nations, and shalt suck the breast of kings; and thou shalt know that I, Jehovah, am thy Saviour, and thy Redeemer, the Mighty One of Jacob. 17 For brass I will bring gold, and for iron I will bring silver, and for wood brass, and for stones iron. A great increase in value in life and posessions. I will also make thy officers peace, and thine exactors righteousness. 18 Violence shall no more be heard in thy land, desolation nor destruction within thy borders; but thou shalt call thy walls Salvation, and thy gates Praise. 19 The sun shall be no more thy light by day; neither for brightness shall the moon give light unto thee: but Jehovah will be unto thee an everlasting light, and thy God thy glory. 20 Thy sun shall no more go down, neither shall thy moon withdraw itself; for Jehovah will be thine everlasting light, and the days of thy mourning shall be ended. 21 Thy people also shall be all righteous; they shall inherit the land for ever, the branch of my planting, the work of my hands, that I may be glorified. 22 The little one shall become a thousand, and the small one a strong nation; I, Jehovah, will hasten it in its time. A great revival with multitudes coming into the Kingdom of God. Isa 61:1-11 The Spirit of the Lord Jehovah is upon me; because Jehovah hath anointed me to preach good tidings unto the meek; he hath sent me to bind up the broken-hearted, to proclaim liberty to the captives, and the opening of the prison to them that are bound; 2 to proclaim the year of Jehovah's favor, and the day of vengeance of our God; to comfort all that mourn; 3 to appoint unto them that mourn in Zion, to give unto them a garland for ashes, the oil of joy for mourning, the garment of praise for the spirit of heaviness; that they may be called trees of righteousness, the planting of Jehovah, that he may be glorified. 4 And they shall build the old wastes, they shall raise up the former desolations, and they shall repair the waste cities, the desolations of many generations. 5 And strangers shall stand and feed your flocks, and foreigners shall be your plowmen and your vine-dressers. 6 But ye shall be named the priests of Jehovah; men shall call you the ministers of our God: ye shall eat the wealth of the nations, and in their glory shall ye boast yourselves. 7 Instead of your shame ye shall have double; and instead of dishonor they shall rejoice in their portion: therefore in their land they shall possess double; everlasting joy shall be unto them. 8 For I, Jehovah, love justice, I hate robbery with iniquity; and I will give them their recompense in truth, and I will make an everlasting covenant with them. 9 And their seed shall be known among the nations, and their offspring among the peoples; all that see them shall acknowledge them, that they are the seed which Jehovah hath blessed. 10 I will greatly rejoice in Jehovah, my soul shall be joyful in my God; for he hath clothed me with the garments of salvation, he hath covered me with the robe of righteousness, as a bridegroom decketh himself with a garland, and as a bride adorneth herself with her jewels. 11 For as the earth bringeth forth its bud, and as the garden causeth the things that are sown in it to spring forth; so the Lord Jehovah will cause righteousness and praise to spring forth before all the nations. Deu 30:1-10 And it shall come to pass, when all these things are come upon thee, the blessing and the curse, which I have set before thee, and thou shalt call them to mind among all the nations, whither Jehovah thy God hath driven thee, 2 and shalt return unto Jehovah thy God, and shalt obey his voice according to all that I command thee this day, thou and thy children,, with all thy heart, and with all thy soul; 3 that then Jehovah thy God will turn thy captivity, and have compassion upon thee, and will return and gather thee from all the peoples, whither Jehovah thy God hath scattered thee. 4 If any of thine outcasts be in the uttermost parts of heaven, from thence will Jehovah thy God gather thee, and from thence will he fetch thee: 5 and Jehovah thy God will bring thee into the land which thy fathers possessed, and thou shalt possess it; and he will do thee good, and multiply thee above thy fathers. 6 And Jehovah thy God will circumcise thy heart, and the heart of thy seed, to love Jehovah thy God with all thy heart, and with all thy soul, that thou mayest live. 7 And Jehovah thy God will put all these curses upon thine enemies, and on them that hate thee, that persecuted thee. 8 And thou shalt return and obey the voice of Jehovah, and do all his commandments which I command thee this day. 9 And Jehovah thy God will make thee plenteous in all the work of thy hand, in the fruit of thy body, and in the fruit of thy cattle, and in the fruit of thy ground, for good: for Jehovah will again rejoice over thee for good, as he rejoiced over thy fathers; 10 if thou shalt obey the voice of Jehovah thy God, to keep his commandments and his statutes which are written in this book of the law; if thou turn unto Jehovah thy God with all thy heart, and with all thy soul. Hos 6:1-3 Come, and let us return unto Jehovah; for he hath torn, and he will heal us; he hath smitten, and he will bind us up. 2 After two days will he revive us: on the third day he will raise us up, and we shall live before him. 3 And let us know, let us follow on to know Jehovah: his going forth is sure as the morning; and he will come unto us as the rain, as the latter rain that watereth the earth. And great revival and restoration will come. Eze 37:1-10 The hand of Jehovah was upon me, and he brought me out in the Spirit of Jehovah, and set me down in the midst of the valley; and it was full of bones. 2 And he caused me to pass by them round about: and, behold, there were very many in the open valley; and, lo, they were very dry. 3 And he said unto me, Son of man, can these bones live? And I answered, O Lord Jehovah, thou knowest. 4 Again he said unto me, Prophesy over these bones, and say unto them, O ye dry bones, hear the word of Jehovah. 5 Thus saith the Lord Jehovah unto these bones: Behold, I will cause breath (Spirit) to enter into you, and ye shall live. 6 And I will lay sinews upon you, and will bring up flesh upon you, and cover you with skin, and put breath (Spirit) in you, and ye shall live; and ye shall know that I am Jehovah. 7 So I prophesied as I was commanded: and as I prophesied, there was a noise, and, behold, an earthquake; and the bones came together, bone to its bone. 8 And I beheld, and, lo, there were sinews upon them, and flesh came up, and skin covered them above; but there was no breath in them. 9 Then said he unto me, Prophesy unto the wind, prophesy, son of man, and say to the wind, Thus saith the Lord Jehovah: Come from the four winds, O breath, and breathe (Spirit) upon these slain, that they may live. 10 So I prophesied as he commanded me, and the breath came into them, and they lived, and stood up upon their feet, an exceeding great army. Isa 2:1-3 The word that Isaiah the son of Amoz saw concerning Judah and Jerusalem. 2 And it shall come to pass in the latter days, that the mountain of Jehovah's house shall be established on the top of the mountains, and shall be exalted above the hills; and all nations shall flow unto it. 3 And many peoples shall go and say, Come ye, and let us go up to the mountain of Jehovah, to the house of the God of Jacob; and he will teach us of his ways, and we will walk in his paths: for out of Zion shall go forth the law, and the word of Jehovah from Jerusalem. Isa 49:13-23 Sing, O heavens; and be joyful, O earth; and break forth into singing, O mountains: for Jehovah hath comforted his people, and will have compassion upon his afflicted. 14 But Zion said, Jehovah hath forsaken me, and the Lord hath forgotten me. 15 Can a woman forget her sucking child, that she should not have compassion on the son of her womb? yea, these may forget, yet will not I forget thee. 16 Behold, I have graven thee upon the palms of my hands; thy walls are continually before me. 17 Thy children make haste; thy destroyers and they that made thee waste shall go forth from thee. The faction is separated from the Bride. 18 Lift up thine eyes round about, and behold: all these gather themselves together, and come to thee. As I live, saith Jehovah, thou shalt surely clothe thee with them all as with an ornament, and gird thyself with them, like a bride. 19 For, as for thy waste and thy desolate places, and thy land that hath been destroyed, surely now shalt thou be too strait for the inhabitants, and they that swallowed thee up shall be far away. 20 The children of thy bereavement shall yet say in thine ears, The place is too strait for me; give place to me that I may dwell. 21 Then shalt thou say in thy heart, Who hath begotten me these, seeing I have been bereaved of my children, and am solitary, an exile, and wandering to and fro? and who hath brought up these? Behold, I was left alone; t
Preserved From The Beast (25) David Eells - 1-2-22 (Audio) Babylon Weaponizes Cells and Computers We just received by faith at random a text we have received many, many times. It is the story of God's apostate people trusting in the strength of man to save them from the DS Babylonish Beast, which is costing their lives. Jer. 43:4-7 So Johanan the son of Kareah, and all the captains of the forces, and all the people, obeyed not the voice of Jehovah, to dwell in the land of Judah. 5 But Johanan the son of Kareah, and all the captains of the forces, took all the remnant of Judah, that were returned from all the nations whither they had been driven, to sojourn in the land of Judah; 6 the men, and the women, and the children, and the king's daughters, and every person that Nebuzaradan the captain of the guard had left with Gedaliah the son of Ahikam, the son of Shaphan; and Jeremiah the prophet, and Baruch the son of Neriah. 7 And they came into the land of Egypt; for they obeyed not the voice of Jehovah: and they came unto Tahpanhes. God's people went to trust in Egypt to save them from Babylon who then went to Egypt and killed them. Jer 43:9-11 Take great stones in thy hand, and hide them in mortar in the brickwork, which is at the entry of Pharaoh's house in Tahpanhes, in the sight of the men of Judah; 10 and say unto them, Thus saith Jehovah of hosts, the God of Israel: Behold, I will send and take Nebuchadrezzar the king of Babylon, my servant, and will set his throne upon these stones that I have hid; and he shall spread his royal pavilion over them. 11 And he shall come, and shall smite the land of Egypt; such as are for death shall be given to death, and such as are for captivity to captivity, and such as are for the sword to the sword. I thought to myself this must be very important to the Lord since we have received this text many times concerning his people going down to Egypt and being killed by the DS Babylon, which represents those trusting in the DS depopulationists to give them a vaccine rather than trust the Lord. Jer 17:5-8 Thus saith Jehovah: Cursed is the man that trusteth in man, and maketh flesh his arm, and whose heart departeth from Jehovah. 6 For he shall be like the heath in the desert, and shall not see when good cometh, but shall inhabit the parched places in the wilderness, a salt land and not inhabited. 7 Blessed is the man that trusteth in Jehovah, and whose trust Jehovah is. 8 For he shall be as a tree planted by the waters, that spreadeth out its roots by the river, and shall not fear when heat cometh, but its leaf shall be green; and shall not be careful in the year of drought, neither shall cease from yielding fruit. DS Babylon just burned a thousand homes in Colorado just like in Paradise with D/E/W weapons. Conservatives and Christians were resisting the DS there. It reminds me of this verse about Babylon taking down the apostate leadership of God's people. Jer 52:13 And he burned the house of Jehovah (Churches), and the king's house (Their leaderships houses); and all the houses of Jerusalem, even every great house (The great men), burned he with fire. Based on these verses I said almost 5 years ago that Babylon would burn churches and leadership homes. Many apostate Church leaders have sent their people to get the vac/cin/es and now they are dying. Backlash is coming. In the US, the Supreme Court has ruled that vaccinated people worldwide are products, patented goods, according to US law, no longer human. Telegram @ Dark Universe Through a modified DNA or RNA vaccination, the mRNA vaccination, the person ceases to be human and becomes the OWNER of the holder of the modified GEN vaccination patent, because they have their own genome and are no longer “human” (without natural people), but “trans-human”, so a category that does not exist in Human Rights. The quality of a natural person and all related rights are lost. This applies worldwide and patents are subject to US law. Since 2013, all people vaccinated with GM-modified mRNAs are legally trans-human and legally identified as trans-human and do not enjoy any human or other rights of a state, and this applies worldwide, because GEN-POINT technology patents are under US jurisdiction and law, where they were registered. Download PDF here: Vaccined No Longer legally human .pdfDownload SOURCE of the decision of the US SUPREME COURT Then this came to me that Michael had found a video that the DS is able to assassinate people by their cellphone. And also the Grap/hine ox/ide computer/cellphone connection is in those who were vac/cin/ated. The thought came to me that they are able to execute these people by cell phone or computer which we know is capable to contact the graphine oxide in the vaccinated to affect their person. This could be done on multitudes of people scattered over a large area and people would just consider that they died of Covid and the educated would believe by the vac/cin/e. Here is the video of a woman who is getting her nails done at a salon. The salon video cameras picked up footage of her cell phone sending out electrical flashes towards her left arm and then she immediately went into convulsions and fell out onto the floor. One Day In 2022 Your Cell Phone May Kill You Or Turn You Into Zombies Before it's News - 12/26/21 Did they figure out how to depopulate humanity using frequency sound weapons, using cell phone tech? I'm not sure they would even need 5G to do that but I do believe that's the plan!! Remember that 2022 is the final year in their three year plan... Frequency weapon…. some of us have seen the videos where people are being frequency attacked by their phones… that's why this video is important. It's likely the woman had the vaxx… did she live or die on the spot? Your Cell Phone May Kill You 1980′s Music Video “Experiment IV” About Frequency Sound Weapon Kate Bush nails it on 1980′s Music Video “Experiment IV” About Frequency Sound Weapons… [Editor's note: This video appears to show an inventor whose heart was to do good to humanity with his invention. I believe this could represent Nicolai Tesla whose revelation and inventions proved that frequencies could heal which was his purpose, however, wicked military people turned this into a weapon on the other end of the scale of frequencies. In the video it appears he was very frustrated and angry this was happening. It appeared to at first be a good thing but ended up being deadly. When it got out in the video it killed many.] The final chilling words of her song, “And the public are warned to stay off.” Here are the lyrics: [Verse 1] We were working secretly for the military. Our experiment in sound was nearly ready to begin. We only know in theory what we are doing. Music made for pleasure, music made to thrill. It was music we were making here, until…[Chorus] They told us all they wanted was a sound that could kill someone from a distance. So we go ahead, and the meters are over in the red. It's a mistake in the making. [Verse 2] From the painful cry of mothers. To the terrifying scream. We recorded it and put it into our machine. [Chorus] But they told us all they wanted was a sound that could kill someone from a distance. So we go ahead, and the meters are over in the red. It's a mistake that we're making. [Bridge] It could feel like falling in love. It could feel so bad. But it could feel so good. It could sing you to sleep. But that dream is your enemy. [Verse 3] We won't be there to be blamed. We won't be there to snitch. (The killers will be far away) I just pray that someone there can hit the switch. [Editor's note: It appears that Tesla tried to turn the switch off but failed.] [Chorus] But they told us all they wanted was a sound that could kill someone from a distance. So we go ahead, and the meters were over in the red. It's a mistake we've made. [Outro] And the public are warned to stay off. Weaponized Cell Phone Theory Demonstrated in the Movie “Cell” [Editor's note: John Cusack and Samuel L. Jackson star in this tale of a mysterious phone signal that turns much of the population into murderous predators. Signature Entertainment releases Cell. [Here is the trailer: https://youtu.be/BCns4w3GA9A ] Zombie Alert Early 2022 Watch the Movie “Cell” Now… It Is Probably A Documentary!! [Editor's note: The DS always tells us what they are going to do before they do it.] (Writer's) Theory: Zombies Created With 5G + Graphene Oxide (Vaxx Ingredient) + Cell Phone!! CONOP 8888 US Dept. Of Defense Strategic Command Zombie Defense Plan Exists!! Airlines Panicking Over 5G Rollout!! Folks… this is important… there IS a zombie event coming… the military AND Pentagon already know!! U.S. military actually made a zombie apocalypse training manual. Yes, really. Internet Culture Published May 14, 2014 - Updated May 31, 2021 If the U.S. is ever attacked by evil magic zombies, or even the relatively tame creature that is a chicken zombie, rest assured that the Department of Defense has it covered. Seriously, a document has apparently been unearthed by Foreign Policy magazine that appears to show either the incredible level of preparedness of the U.S. national security community, or it demonstrates how the people tasked with keeping the nation safe are insane. The zombie attack training manual, “CONOP 8888,” or “Counter Zombie Dominance,” is dated April 2011, and was supposedly found buried on a secret military computer. It tells military planners how to defeat an invasion of flesh eaters, (Editor's note: Remember he outbreak of zombies that were devouring peoples faces.) and how to preserve the sanctity of “non-zombie life.” From magic zombies to chicken zombies, even vegetarian zombies, they're all in the file, with a plan for how to take them out. “Zombies pose a threat to all non-zombie human life,” says CONOP8888. “[Strategic Command] will be prepared to preserve the sanctity of human life and conduct operations in support of any human population—including traditional adversaries.” While the manual says in its disclaimer that “this plan was not acutally designed as a joke,” it still kind of is. What the intelligence community has done here is use “zombie” as a kind of code word for “enemy,” so as not to look like the Pentagon is planning for an invasion of a particular country, religion, or plague. To prepare for all possible situations, it says, “We elected to use a completely-impossible scenario that could never be mistaken for a real plan.” All of which begs the question, of course, if zombies are being used as metaphors for real threats, what... are “Vegetarian zombies” doing in there? Chicken zombies could, of course, mean avian bird flu, and evil magic zombies could easily be a thinly veiled reference to Al' Qaeda or some other real enemy. But there can be no such thing as a vegetarian zombie. And second, what threat do vegetarians pose, either in this universe or the one inhabited by the person who wrote this manual? In fact, according to the military zombie survival guide, vegetarian zombies “pose no direct threat to humans because they only eat plant life,” which makes total sense… CONOP 8888 also known as Counter-Zombie Dominance is a U.S. Department of Defense Strategic Command CONOP document that describes a plan for defending against zombies. The April 30, 2011 document depicts fictional scenarios of zombie attacks for training students in military planning. Read the full zombie apocalypse training manual below: CONPLAN 8888 Now if that was all bad enough… the airlines are panicking over 5G (The opening scene of the movie “Cell” takes place in airport!!) What do they know???? Planned 5G Wireless Deployment Could Compromise Airline Safety, Aviation Executives Warn Newsweek - Justin Klawans - Dec 21, 2021 Aviation executives expressed their fears Monday that the potential coming deployment of 5G wireless technology could harm the airline industry. In a joint letter acquired by Reuters addressed to the U.S. Department of Transportation (DOT), Boeing CEO Dave Calhoun and Airbus Americas CEO Jeffrey Knittel urged DOT Secretary Pete Buttigieg to postpone the upcoming rollout of the technology, citing multiple concerns. "5G interference could adversely affect the ability of aircraft to safely operate," the letter stated, adding that the rollout of the technology could have "an enormous negative impact on the aviation industry.” Both AT&T and Verizon are planning to deploy C-band spectrum 5G wireless networks across the United States on Jan. 5. The technology was originally slated to go online in November, but the companies agreed to push the date into 2022 after concerns were cited, and now the airline executives are hoping to slide that date even further down the calendar. The airplane manufacturers, who are typically considered direct competitors, came together in a rare show of unity to voice concerns that the 5G initiative could lead to numerous delays at airports throughout the country. The pair of companies represent the vast majority of the airplanes built for commercial aviation use, and they also have a large market share of military aircraft. The letter from Boeing and Airbus cited a statistic from trade group Airlines for America, which stated that if 5G had been in effect in 2019, it would've resulted in the delay or cancellation of 345,000 passenger flights and 5,400 cargo flights. The sentiment from the airline executives echoed a report released Dec. 7 from the U.S. Federal Aviation Administration (FAA) that said 5G technology could lead to scheduling problems and safety issues in the skies. After issuing its report, the FAA went on to present a pair of airworthiness directives that would prohibit aircraft from operating certain radio functions while in the area of 5G signals. "Because radio altimeter anomalies that are undetected by the aircraft automation or pilot, particularly close to the ground ... could lead to loss of continued safe flight and landing," one of the directives stated. However, the FAA later issued a statement in which it said that the "expansion of 5G and aviation will safely co-exist." Verizon also released a statement pushing back against the FAA guidelines, stating that "there is no evidence that 5G operations using C-band spectrum pose any risk to aviation safety, as the real-world experience in dozens of countries already using this spectrum for 5G confirms." The communications giant added that it was taking "additional steps to minimize energy coming from 5G base stations." However, in spite of the statements released by multiple parties, the Air Line Pilots Association stated Monday that the discussions regarding 5G were at a stalemate, adding that it was "a big problem for passengers, shippers and the American economy.” Equally important to look at is what is in the vaccines: Look At The Freaky Live Blood Sample Of Vaxxed Under Microscope!! “The Thing” Is Definitely Alive, As Are Other Strange Unidentified Creatures Swimming Around In Blood Sample Of Vaxxed!! It's Like An Ecosystem Humanity Has Never Seen Before!! Dr. Ariyana Love said, "I agree with what one scientist suggested… that the reason the vaxxes are kept under extremely cold storage, is to keep the creatures under a suspended animation… until they are thawed out, and activated by human temperatures. Now looking at this blood sample.. it's clear we can see several creatures moving about, a blue colourful ‘thing', and a large ‘hydra'-like creature, that some are suggesting might be able to self-regenerate itself, and therefore is basically, immortal. The tinier critters look rather ‘active' and like they are more developed than simple bacteria… I wonder what everybody is doing… probably eating stuff, eliminating waste and reproducing. Most likely… what this means, is that the blood of the vaxxed has likely become a literal alien-hybrid cesspool of waste byproducts, and who knows what else… we're still finding out! Folks… we could be looking at an alien invasion under microscope… and at the very least, the new blood of the new hybrid (human)!” Is This Why They Want to Change our DNA? Source: Uncensored Sam, Published September 9, 2021 God's true name is recorded within our DNA. So, just let me go ahead and explain. Our chains of DNA contain four nucleotide-based pairs called Adenine, Guanine, Thiamine, and Cytosine. And then there's a unit within the DNA strand called a sulfuric bridge. This sulfuric bridge holds our entire DNA strand together. It only appears after every ten nucleic acids have been laid down, and then after every five nucleic acids, then after every six, and then again, after every five nucleic acids. So, we get this repeating numerical value of 10, 5, 6, 5 within our DNA strand. Well, it turns out the Biblical name for God, YHWH, contains the same numerical value as our DNA strand. Yod He Vav He equals ten, five, six, five. What's even more interesting is that if you take the Hebrew name of YHWH and place it on its side, you get the image of a human being. Part three of this video series suggests that DNA is a language. Many people were wondering what god made the language of DNA. Researchers at Harvard University announced today that they have found what appears to be a message from God written inside the human genome. In a little-explored section of non-coding DNA, a team of top geneticists discovered a 22-word snippet of ancient Aramaic in which God confirms this existence and His role in creating life on Earth. “We knew the patterns weren't naturally occurring,” explains Charles Watson, the lead scientist on the project, “but we couldn't come up with any convincing explanation for them. On a whim, we started cross-referencing the patterns with language databases,” he explains, “and we were shocked to find that the patterns corresponded to ancient Aramaic.” Stunned by its discovery, the team contacted language experts familiar with Aramaic – the language Jesus Christ spoke in daily life. Entirely decoded, the message reads: Hello my children, This is Yahweh, the One True Lord. You have found creation's secret. Now…go tell the world Who is the true God and Creator of all! Rumble Video: IS THIS Why They Want to Change our DNA? Covid Shots Turn Humanity Into Patentable Species!! Supreme Court Ruling, And It's In The Patents!! Covid Shots Turn Humanity Into Patentable Species!! Supreme Court Ruling, And It's In The Patents!! Zombie Invasion Begins Mid-January 2022… Along With Mass Sickness And Death Especially For The Jabbed. Zombie Invasion Begins Mid-January 2022… Along With Mass Sickness And Death Especially For The Jabbed!! Make The Omicron/Zombie/Disease X Connection Now And Then Head For The Hills!! One News - December 23, 2021 People… what we have here, is proof, that there is collusion and conspiracy for mass murder, and zombification of humanity on a scale that defies most people's awareness. For starters you must understand that new technologies especially of the electromagnetic radiation kind, tend to coincide with new illnesses. This has been going on for DECADES. Now… the latest is the 5G rollout… a major step scheduled for early January. I'd like you to simply observe the mass media…. two things are ‘scheduled: 1. 5G rollout… a new wave of 5G tech is set to become active. https://duckduckgo.com/?q=++5g+rollout+january&atb=v255-1&iar=news&ia=news 2. Media keeps suggesting people will get sick early January! https://duckduckgo.com/?q=+january+new+variant&atb=v255-1&iar=news&ia=news 3. They seem to know something about ‘Disease X' aka 5G radiation sickness. https://duckduckgo.com/?q=disease+x&atb=v255-1&iar=news&ia=news Gee how do they know? They know because they know 5G is going to make people sick… and even worse. They know the graphene oxide in the vaxxed, is activated by electromagnetic radiation. This Is What Will Create Zombies!! Watch Graphene Oxide Dance To A Frequency In A Lab!! What This Means Is That Vaxx Ingredient Can Be Frequency Adjusted To Do… They know graphene oxide at the molecular level is equivalent of tiny razor blades; a leading scientist was murdered for telling the world this FACT! If you have the jab or several… you probably have lots to be concerned about with 5G. [Editor's note: Fear not… Lo, I will be with you always. From here on down he is speaking to non-believers.] If I were you… I'd pretty much be heading to the countryside. [Editor's note: Since cities are where most of the sin happens and most of the judgment comes, I always recommend people move out of the cities and away from the fault lines and sea shores.] How are you going to live, when tiny razor blades are slicing through your body… 24/7? [Editor's note: Those who believe the Word of God will live by Psalm 91, where it says, “There shall no evil befall thee." and the Passover, which is where God exercised control over the destroyer for those who lived under the blood. Jesus said in Luk 10:19 Behold, I have given you authority to tread upon serpents and scorpions, and over all the power of the enemy: and nothing shall in any wise hurt you.] How are you going to be healthy? How are you going to survive? [Learn from God's Vaccine Book] How will your body repair itself, as all the organs and capillaries are receiving 1000's of tiny slices… non-stop! [Remember, "nothing shall in any wise hurt you."] 5G is bad enough if you are not jabbed, but if you are, it might be a death sentence, or at the very least, the end of your body as you know it. [Gal 3:13 Christ redeemed us from the curse of the law, having become a curse for us; for it is written, Cursed is every one that hangeth on a tree:] Face it… what if graphene oxide is in the brain, and then you expose yourself to that radiation that is 100x stronger than 4G? [Pro 10:2 Treasures of wickedness profit nothing; But righteousness delivereth from death.] Now… this is also a trend in the news… the airlines are already bracing people for weirdness. Imagine a vaxxed pilot exposed constantly to 5G… to me, it's like a scenario of the rise of the zombies. Their brains will be sliced over and over by tiny razor blades one molecule thick. This will surely be the rise of the zombies. This sounds like a big joke right? MILITARY DOES NOT THINK SO and they are also EXPERTS IN ELECTROMAGNETIC WARFARE! Hundreds of military, law enforcement and medical personnel will observe the Hollywood-style production of a zombie attack as part of their emergency response training. We've put some links below: https://duckduckgo.com/?q=military+zombie+training&atb=v255-1&ia=web Marines, police prep for mock zombie invasion | Fox News https://www.foxnews.com › us › marines-police-prep-for-mock-zombie-invasion You need to know that they don't have a real accurate test for omicron… or the other variants, or covid. That's why they are ‘phasing out' the PCR test… they use this term ‘phase out' instead of ‘it never worked' to avoid admission of guilt for crimes against humanity… or let's be blunt, this is the greatest crime against humanity that has ever been perpetrated, and they won't stop unless humanity figures things out and stops them… GRAPHENE OXIDE AND THE END-OF-DAYS APOCALYPSE Posted on August 12, 2021 by State of the Nation Dr. José Luis Sevillano expresses his theory that GRAPHENE OXIDE (GO) is the Bio-Tech ingredient chosen for controlling mankind in THE NEW WORLD ORDER as defined by the DAVOS, the Bildebergs and WWII NAZI collaborator, Klaus Schwab, who founded the Word Economic Forum. Graphene Oxide (GO) is found in the current Covid-19 vaccines. GO is a super- conductor with unique electromagnetic properties that can facilitate the altering of human genetics. The Covid-19 mRNA vaccines are the trial run for the “genetic Apocalypse”. The plan is to alter the human species to install population control and coercive slavery through injection of Graphene Oxide into the blood stream where intra-cellular conductivity will allow neura-link (Elon Musk) nano technology and remote control of the human body and brain using directed electromagnetic radiation of various frequencies… https://www.orwell.city/2021/08/graphene-and-reset.html They are desperate to get this Graphene Oxide into people any way they can including, Spraying it in the Air, putting it in food and the nasal swabs for the PCR tests. Sep 23, 2021 - RED ALERT: Aerosolized skin-penetrating nanoparticle spike protein attack vector CONFIRMED https://www.brighteon.com/358dc7fe-2580-40c6-8a90-13a13175caf5 Operation Disclosure: "Former FEMA Whistleblower Celeste Solum explains that the Corona PCR “test” is implanting a microchip So the Nasopharyngeal Covid19 PCR “tests” were never tests at all. They are implanting chips, inserting Nanobots called Nanites with a bioweapons payload for the brain, while at the same time harvesting DNA. The PCR swab is inserted straight to the Nasopharynx behind the nose and forehead where your eyes are. It's at the blood brain barrier and next to your pineal gland. I believe they are knocking out people's senses with these Bioweapons and killing human intuition and your ability to cognitively see what they are doing to us. They're knocking out our senses and targeting the brain with Nanites that carry a payload. Decline the “tests.” Refuse the masks. Don't let them implant the microchip.” Here are some very informative links explaining Graphene Oxide; It's history and what they plan on using it for: https://www.holistichealthonline.info/graphene-oxide-basics/ https://www.ftwproject.com/ref/6/ GRAPHENE OXIDE, 5G AND COVID PRESENTATION AND NOTES ON SGT REPORT Here is a quote from Klaus Schwab's book, “Covid - 19: The Great Reset: “Euthanasia for the terminally ill and the aged shall be compulsory. No cities shall be larger than a predetermined number as described in the work of Kalgeri. Essential workers will be moved to other cities if the one they are in becomes overpopulated. Other non-essential workers will be chosen at random and sent to underpopulated cities to fill "quotas”. At least 4 billion “useless eaters” shall be eliminated by the year 2050 by means of limited wars, organized epidemics of fatal rapid-acting diseases and starvation. Energy, food and water shall be kept at subsistence levels for the non-elite, starting with the White populations of Western Europe and North America and then spreading to other races. The populations of Canada, Western Europe and the United States will be decimated more rapidly than on other continents, until the world's population reaches a manageable level of 1 billion, of which 500 million will consist of Chinese and Japanese races, selected because they are people who have been regimented for centuries and who are accustomed to obeying authority without question. From time to time there shall be artificially contrived food and water shortages and medical care to remind the masses that their very existence depends on the good will of the Committee of 300.” The Culling of the Human Race Part 2 BY GERI UNGUREAN - 11/21/20 Altering DNA – Luciferase Biogel – Implantable Biochip to be Tracked by 5G Technology- It Isn't a Conspiracy Theory When They Are Openly Telling You What They Want To Do First and foremost, I encourage the reader to watch this short video in which Dr. Carrie Madej explains the mRNA Vaccine in terms that we can understand. She is a brave woman to openly expose the dangerous, DNA-changing vaccine. DARPA funded implantable biochip can potentially deploy Moderna's mRNA vaccine From nanotechnology.news In a bid to try to battle the ongoing Wuhan coronavirus (COVID-10) pandemic, the Defense Advanced Research Projects Agency (DARPA) is funding the development of an implantable biochip that could be deployed as soon as next year. The chip is said to be able to deploy an experimental new vaccine, developed jointly by Moderna and U.S government, that could change human DNA. The chip and the vaccine built on a breakthrough made by then-Harvard University professor and eventual Moderna co-founder Derek Rossi in 2010. In his discovery, which the now-retired scientist says came about purely by accident, Rossi claimed that he found a way to “reprogram” messenger ribonucleic acid (mRNA) – the molecules that carry genetic instructions for cell development in the human body. The promise provided by Rossi's breakthrough was such that it allowed him to co-found Moderna with private equity firm Flagship Pioneering. The company then attracted almost half a billion dollars from the federal government to begin developing vaccines using the new technology. In a preliminary report last July funded by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health (NIH), Moderna's mRNA-1273 vaccine was found to have “induced anti–SARS-CoV-2 immune responses in all participants and no trial-limiting safety concerns were identified.” Despite this, however, one obstacle to the deployment of Moderna's vaccine is the method of delivery. While Moderna is developing its own system, it's unlikely to get Food and Drug Administration (FDA) approval any time soon. Enter Profusa, which is developing a nanoscale biochip that can detect symptoms of an infection. Profusa's biochip is made using a technology called “hydrogels” that were a product of the “In Vivo Nanoplatforms” (IVN) program that DARPA's Biological Technologies Office (BTO) launched in 2014 to develop implantable nanotechnologies. These hydrogels are soft, flexible nanomachines that are injected beneath the skin to perform monitoring. This hydrogel includes a specially engineered molecule that sends a fluorescent signal outside the body when it begins to fight infection. This signal can then be detected by a sensor attached to the skin that can then be sent to an app or even to a doctor's website. When it was first tested in 2018, this hydrogel was being used to measure glucose, oxygen and lactate levels. However, this past March, the company quietly announced that it was conducting a study to see if the technology could be used to detect respiratory diseases, including COVID-19. More importantly, Profusa's biochip is expected to receive fast-track authorization from the FDA by early 2021. With this in mind, some are speculating that the biochip will more than likely be the candidate for the mRNA vaccine's delivery. Read rest of article HERE From mintpress.com The most significant scientific discovery since gravity has been hiding in plain sight for nearly a decade and its destructive potential to humanity is so enormous that the biggest war machine on the planet immediately deployed its vast resources to possess and control it, financing its research and development through agencies like the National Institutes of Health (NIH), the Defense Advanced Research Projects Agency (DARPA) and HHS' BARDA. The revolutionary breakthrough came to a Canadian scientist named Derek Rossi in 2010 purely by accident. The now-retired Harvard professor claimed in an interview with the National Post that he found a way to “reprogram” the molecules that carry the genetic instructions for cell development in the human body, not to mention all biological lifeforms. These molecules are called ‘messenger ribonucleic acid' or mRNA and the newfound ability to rewrite those instructions to produce any kind of cell within a biological organism has radically changed the course of Western medicine and science, even if no one has really noticed yet. As Rossi, himself, puts it: “The real important discovery here was you could now use mRNA, and if you got it into the cells, then you could get the mRNA to express any protein in the cells, and this was the big thing.” It was so big that by 2014, Rossi was able to retire after the company he co-founded with Flagship Pioneering private equity firm to exploit his innovation, – Moderna Inc., attracted almost a half billion dollars in federal award monies to begin developing vaccines using the technology. No longer affiliated with Moderna beyond his stock holdings, Rossi is just “watching for what happens next” and if he's anything like the doting “hockey dad” he is portrayed to be, he must be horrified. Remote control biology As early as 2006, DARPA was already researching how to identify viral, upper respiratory pathogens through its Predicting Health and Disease (PHD) program, which led to the creation of the agency's Biological Technologies Office (BTO), as reported by Whitney Webb in a May article for The Last American Vagabond. In 2014, DARPA's BTO launched its “In Vivo Nanoplatforms” (IVN) program, which researches implantable nanotechnologies, leading to the development of ‘hydrogel'. Hydrogel is a nanotechnology whose inventor early on boasted that “If [it] pans out, with approval from FDA, then consumers could get the sensors implanted in their core to measure their levels of glucose, oxygen, and lactate.” This contact lens-like material requires a special injector to be introduced under the skin where it can transmit light-based digital signals through a wireless network like 5G. Once firmly implanted inside the body, human cells are at the mercy of any mRNA program delivered via this substrate, unleashing a nightmare of possibilities. It is, perhaps, the first true step towards full-on transhumanism; a “philosophy” that is in vogue with many powerful and influential people, such as Google's Ray Kurzweil and Eric Schmidt and whose proponents see the fusion of technology and biology as an inevitable consequence of human progress. The private company created to market this technology, that allows for biological processes to be controlled remotely and opens the door to the potential manipulation of our biological responses and, ultimately, our entire existence, is called Profusa Inc and its operations are funded with millions from NIH and DARPA. In March, the company was quietly inserted into the crowded COVID-19 bazaar in March 2020, when it announced an injectable biochip for the detection of viral respiratory diseases, including COVID-19. Read rest of article HERE This next article REALLY caught my attention. These bad actors on the world stage are not even trying to hide anything from the public. I believe that this has happened because of the FEAR TACTIC. Many people who have given up their liberties and have cloistered themselves in their homes are TERRIFIED. Klaus Schwab is the head of the WEF (World Economic Forum). This man is salivating over the coming New World Order. Klaus Schwab: Great Reset Will “Lead to a Fusion of Our Physical, Digital and Biological Identity” From summitnews.com Globalist Klaus Schwab made it clear that transhumanism is an integral part of “The Great Reset” when he said that the fourth industrial revolution would “lead to a fusion of our physical, digital and biological identity,” which in his book he clarifies is implantable microchips that can read your thoughts. As we highlighted earlier, “The Great Reset” is attracting a deluge of fresh attention in the aftermath of the coronavirus pandemic, which Canadian Prime Minister Justin Trudeau said was an “opportunity for a reset.” The agenda is primarily based around dismantling the current capitalist system in favor of greater centralized technocrat rule which will lead to lower living standards, less fuel consumption, fewer civil liberties and the accelerated automation of jobs. However, another key aspect to “The Great Reset,” or the “fourth industrial revolution” as Schwab calls it, is merging man with machine. #TheGreatReset #4IR https://t.co/1ZjrP7F8RQ Schwab went on to explain how his book, ‘Shaping the Future of The Fourth Industrial Revolution', was particularly popular in China, South Korea and Japan, with the South Korean military alone purchasing 16,000 copies. In the book, Schwab explains with excitement how upcoming technology will allow authorities to “intrude into the hitherto private space of our minds, reading our thoughts and influencing our behavior.” He goes on to predict that this will provide an incentive for law enforcement to implement Minority Report-style pre-crime programs. “As capabilities in this area improve, the temptation for law enforcement agencies and courts to use techniques to determine the likelihood of criminal activity, assess guilt or even possibly retrieve memories directly from people's brains will increase,” writes Schwab. “Even crossing a national border might one day involve a detailed brain scan to assess an individual's security risk.” Schwab also waxes lyrical about the transhumanist utopian dream shared by all elitists which will ultimately lead to the creation of human cyborgs. “Fourth Industrial Revolution technologies will not stop at becoming part of the physical world around us—they will become part of us,” writes Schwab. “Indeed, some of us already feel that our smartphones have become an extension of ourselves. Today's external devices—from wearable computers to virtual reality headsets—will almost certainly become implantable in our bodies and brains.” Schwab also openly endorses something the media still claims is solely a domain of discussion for conspiracy theorists, namely “active implantable microchips that break the skin barrier of our bodies.” The globalist hails the arrival of “implanted devices (that) will likely also help to communicate thoughts normally expressed verbally through a ‘built-in' smartphone, and potentially unexpressed thoughts or moods by reading brain waves and other signals.” So in other words, the “fusion of our physical, digital and biological identity” relates to the transhumanist singularity and a future where people have their every movement tracked and every thought read by an implantable microchip. It isn't a “conspiracy theory” when they're openly telling you what they want to do. source I want to say something very important to the brethren. The Cov-19 vaccine is NOT the Mark of the beast! … [Editor's note: This technology now is not the Mark of the Beast because this starts in the middle of the tribulation. So here is the mid-trib Mark of the Beast.] Rev. 13:11-18 “Then I saw another beast coming up out of the earth, and he had two horns like a lamb and spoke like a dragon. And he exercises all the authority of the first beast in his presence, and causes the earth and those who dwell in it to worship the first beast, whose deadly wound was healed. He performs great signs, so that he even makes fire come down from heaven on the earth in the sight of men. And he deceives those who dwell on the earth by those signs which he was granted to do in the sight of the beast, telling those who dwell on the earth to make an image to the beast who was wounded by the sword and lived. He was granted power to give breath to the image of the beast, that the image of the beast should both speak and cause as many as would not worship the image of the beast to be killed. He causes all, both small and great, rich and poor, free and slave, to receive a mark on their right hand or on their foreheads, and that no one may buy or sell except one who has the mark or the name of the beast, or the number of his name. Here is wisdom. Let him who has understanding calculate the number of the beast, for it is the number of a man: His number is 666... Those on the earth during this time who come to the realization that Christ is Lord – they will refuse to take the mark. They will also be hunted down by the armies of Antichrist and will be beheaded. But their souls will be in heaven with our Precious Lord Jesus. Remember this passage of Scripture? Rev. 6:10 And they cried with a loud voice, saying, “How long, O Lord, holy and true, until You judge and avenge our blood on those who dwell on the earth?” These were those who were slaughtered for their faith by Antichrist. They are asking the Lord “How long before He will judge and avenge their blood?” Brethren, I hope that this has helped some who worry about the vaccine being the actual mark of the beast. But I still say DO NOT GET THE VACCINE!! It changes our DNA which is God-given! Pray and share the saving Gospel of Jesus Christ with the lost. Time is short! Conquering Your Beast Holiness or sanctification is a refuge from the Beast as a highway of holiness that leads to Zion. The unclean cannot travel this highway. “Righteousness delivereth from death.” The Beast is always given authority to crucify the flesh. If a person is dead to self, which is a gift from God, they never have to worry about the Beast. Isa 35:1-10 The wilderness (Tribulation in Revelation 12 & 17) and the dry land shall be glad; and the desert shall rejoice, and blossom as the rose. 2 It shall blossom abundantly, and rejoice even with joy and singing; the glory of Lebanon shall be given unto it, the excellency of Carmel and Sharon: they shall see the glory of Jehovah, the excellency of our God. 3 Strengthen ye the weak hands, and confirm the feeble knees. 4 Say to them that are of a fearful heart, Be strong, fear not: behold, your God will come with vengeance, with the recompense of God; he will come and save you. 5 Then the eyes of the blind shall be opened, and the ears of the deaf shall be unstopped. 6 Then shall the lame man leap as a hart, and the tongue of the dumb shall sing; for in the wilderness shall waters break out, and streams in the desert. 7 And the glowing sand shall become a pool, and the thirsty ground springs of water: in the habitation of jackals, where they lay, shall be grass with reeds and rushes. 8 And a highway shall be there, and a way, and it shall be called The way of holiness; the unclean shall not pass over it; but is shall be for the redeemed: the wayfaring men, yea fools, shall not err therein. 9 No lion shall be there, nor shall any ravenous beast go up thereon; they shall not be found there; but the redeemed shall walk there: 10 and the ransomed of Jehovah shall return, and come with singing unto Zion; and everlasting joy shall be upon their heads: they shall obtain gladness and joy, and sorrow and sighing shall flee away. Luk 21:34-36 But take heed to yourselves, lest haply your hearts be overcharged with surfeiting, and drunkenness, and cares of this life, and that day come on you suddenly as a snare: 35 for so shall it come upon all them that dwell on the face of all the earth. 36 But watch ye at every season, making supplication, that ye may prevail to escape all these things that shall come to pass, and to stand before the Son of man. {Rev.12:9} And the great dragon was cast down, the old serpent, he that is called the Devil and Satan, the deceiver of the whole world; he was cast down to the earth, and his angels were cast down with him. {10} And I heard a great voice in heaven, saying, Now is come the salvation, and the power, and the kingdom of our God, and the authority of his Christ: for the accuser of our brethren is cast down, who accuseth them before our God day and night... {13} And when the dragon saw that he was cast down to the earth, he persecuted the woman that brought forth the man [child]. {14} And there were given to the woman the two wings of the great eagle, that she might fly into the wilderness unto her place, where she is nourished for a time, and times, and half a time, from the face of the serpent.
If there is one rule in biology, it is that there is an exception to every rule. This includes even the basic biochemistry of DNA, which was once thought to be universal. On this episode, host Lauren Richardson and Judy Savitskaya (a16z bio deal team member and synthetic biology expert), discuss the results and implications three related articles co-published in Science, which all advance our understanding of a very unique kind of DNA. If you open any biology text book, it will say that the genetic code is made up of 4 bases: Adenine, Thymine, Cytosine, and Guanine, or ATCG. But, back in 1977, scientists discovered a phage — the technical term a virus that infects bacteria — that encodes its genome in ZTCG. Z is a derivative of A that has an extra amino group tagged on, and while that may sound minor, it changes some of the key properties of DNA. These three new articles seek to understand how Z is made and how it is incorporated into DNA. This is essential information for taking Z from a weird, wild bio story into a practical application. The conversation covers what makes Z different than other bases, what these three articles reveal about the synthesis and polymerization of Z, and how we can use use Z in a wide range of applications, from bio-containment to new therapeutics to DNA storage.The three articles discussed are:"A widespread pathway for substitution of adenine by diaminopurine in phage genomes" by Yan Zhou, Xuexia Xu, Yifeng Wei, Yu Cheng, Yu Guo, Ivan Khudyakov, Fuli Liu, Ping He, Zhangyue Song, Zhi Li, Yan Gao, Ee Lui Ang, Huimin Zhao, Yan Zhang, and Suwen Zhao"A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes" by Dona Sleiman, Pierre Simon Garcia, Marion Lagune, Jerome Loc’h, Ahmed Haouz, Najwa Taib, Pascal Röthlisberger, Simonetta Gribaldo, Philippe Marlière, and Pierre Alexandre Kaminski"Noncanonical DNA polymerization by aminoadenine-based siphoviruses" by Valerie Pezo, Faten Jaziri, Pierre-Yves Bourguignon, Dominique Louis, Deborah Jacobs-Sera, Jef Rozenski, Sylvie Pochet, Piet Herdewijn, Graham F. Hatfull, Pierre-Alexandre Kaminski, and Philippe Marliere
My AP Biology Thoughts Episode #48Welcome to My AP Biology Thoughts podcast, my name is Pauline and I am your host for episode #48 called Unit #1 Chemistry of Life: Nucleic Acids Structure Function & Examples. Today we will be discussing an overview of nucleic acids in terms of their components, function, and examples. Segment 1: Introduction to Nucleic Acids Structure Function & Examples Nucleic Acids are one of the big macromolecules necessary for life. They are complex organic substances present in living cells whose molecules consist of many nucleotides linked in a long chain. Let's first talk about what makes up nucleic acids. Their monomers are nucleotides which are all made up of a phosphate group, a pentose sugar, and a nitrogenous base as shown in the diagram. The nitrogen atoms in the nitrogenous base are the extra element that differentiates nucleic acids from the three other macromolecules with the abbreviation CHOPN. Through a dehydration reaction, nucleotides link together with a phosphodiester linkage which is between the sugar and phosphate groups. The drawing shows a water molecule taken out to form this a covalent bond. The nucleotides bonded together make up the polymers of nucleic acids which are DNA and RNA. Segment 2: Example of Nucleic Acids Structure FunctionDNA and RNA are the main two examples of nucleic acids. There are major differences as well as similarities between DNA and RNA that are important to know. DNA, also known as deoxyribonucleic acid, is made up of the deoxyribose sugar, is double stranded and arranged in an antiparallel pattern. DNA is always found in the nucleus of eukaryotic cells and contains information for thousands of proteins. Its bases are cytosine, guanine, adenine, and thymine. On the other hand, RNA uses all of these bases except thymine is replaced by uracil. RNA is also only single stranded and contains information for only one protein as it leaves the nucleus after formation. They are similar in their directionality and bonding. Their nucleotides are all linked by covalent bonds and have a 3' to 5' directionality. The linear sequence of nucleotides have ends, defined by the 3' hydroxyl and 5' phosphates of the sugar in the nucleotide. During DNA and RNA synthesis, nucleotides are added to the 3' end of the growing strand, resulting in the formation of a covalent bond between nucleotides. Since DNA is structured as an antiparallel double helix, each strand runs in the opposite 5' to 3' orientation. This means that adenine nucleotides pair with thymine nucleotides via two hydrogen bonds. Cytosine nucleotides pair with guanine nucleotides by three hydrogen bonds. This is all shown in this diagram where the black boxes are where another nucleotide would be added, and there are more hydrogen bonds highlighted in pink between Guanine and cytosine because of the antiparallel double helix. Segment 3: Digging Deeper Nucleic Acids Structure Function & ExamplesNucleic acids fit in the greater picture of the unit called Chemistry of Life because of their functions. As mentioned before, they carry information for making proteins which brings back the topic of the central dogma. Through transcription, the information in a strand of DNA is copied into a new molecule of messenger RNA, which is then decoded during the process of translation to build a polypeptide. Humans cannot survive without all nine essential amino acids found in proteins, so nucleic acids are essential for protein synthesis. DNA and RNA also have a hereditary function because it is inherited from parent to offspring, so is responsible for any gene mutations and the genetic biodiversity of populations. Just to highlight just how important nucleic acids are, DNA is the blueprint for life. Thank you for listening to this episode of My AP Biology Thoughts. For more student-ran podcasts and digital content, make sure that you...
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.26.354787v1?rss=1 Authors: Luo, R., Wong, Y.-S., Lam, T.-W. Abstract: Motivation: Danchin et al. have pointed out that cytosine drives the evolution of SARS-CoV-2. A depletion of cytosine might lead to the attenuation of SARS-CoV-2. Results: We built a website to track the composition change of mono-, di-, and tri-nucleotide of SARS- CoV-2 over time. The website downloads new strains available from GISAID and updates its results daily. Our analysis suggests that the composition of cytosine in coronaviruses is related to their reported mortality. Using 137,315 SARS-CoV-2 strains collected in ten months, we observed cytosine depletion at a rate of about one cytosine loss per month from the whole genome. Availability: The website is available at http://www.bio8.cs.hku.hk/sarscov2/. Copy rights belong to original authors. Visit the link for more info
Dr Norman Cohen introduces four key characteristics any set of inherited instructions needs to have.
Transcript -- Dr Norman Cohen introduces four key characteristics any set of inherited instructions needs to have.
Dr Norman Cohen introduces four key characteristics any set of inherited instructions needs to have.
Transcript -- Dr Norman Cohen introduces four key characteristics any set of inherited instructions needs to have.
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 04/19
Die Grundlage für die Entstehung von Tumoren bildet der Erwerb genetischer Veränderungen, wobei neben Mutationen wie Chromosomeninstabilitäten, Insertionen, Deletionen oder Basenmutationen auch epigenetische Vorgänge von Bedeutung sind. Hierzu zählt die veränderte Methylierung von DNA in neoplastisch transformierten Zellen, die bei einigen Genen in deren transkriptionellen Inaktivierung resultiert. Im Rahmen der vorliegenden Arbeit sollten Kolon- und Magenkarzinome auf bestehende Methylierungsdefekte in zwei Genen untersucht werden. Im ersten Teil wurde ein in die Mismatch-Reparatur involviertes Gen, das hMLH1-Gen, untersucht. Gastrointestinale Karzinome wurden hierbei hinsichtlich eines Zusammenhangs zwischen ihrer Mikrosatelliten- instabilität und einer möglichen Methylierung von Cytosinbasen im hMLH1-Promotor analysiert. Hierfür kam die Bisulfitmethode zur Anwendung, bei der die Umwandlung von unmethylierten Cytosinbasen zu Uracil erfolgt und die damit die Grundlage für die anschließende methylierungssensitive PCR bildet. Insgesamt ließ sich die Mikrosatelliten- instabilität bei sieben von neun untersuchten Karzinomproben auf Methylierung der proximalen Promotorsequenz zurückführen. Der Methylierungsstatus der beiden übrigen mikrosatelliteninstabilen Tumoren konnte nicht eindeutig bestimmt werden, obwohl die Vollständigkeit der Bisulfitmodifikation über den Nachweis des maternalen Methylierungsmusters des Exons 1 von SNRPN bestätigt wurde. Überdies konnte eine Deletion dieser Sequenz mittels Überprüfung der unbehandelten DNA ausgeschlossen werden. Gegenstand des zweiten Teils dieser Arbeit war die Untersuchung des CD95-Gens, eines Mitglieds der Tumor- Nekrose-Faktor-Rezeptor-Familie (sog. Todesrezeptoren), das eine entscheidende Rolle bei der ungestörten Apoptose von Zellen spielt. Grundlage hierfür waren die Ergebnisse von Peli et al., 1999, denen zufolge die CD95-Expression in mehreren etablierten Säugetierzellinien durch onkogenes Ras (H-Ras) herunterreguliert wird, wodurch sich eine Resistenz der Zellen für CD95L-induzierte Apoptose entwickelt. Hinweise aus den genannten Untersuchungen, die Inaktivierung von CD95 sei möglicherweise durch Methylierung des Promotors verursacht, sollte in der vorliegenden Arbeit anhand von gastrointestinalen Karzinomen näher analysiert werden. Hierzu wurde der Methylierungsstatus von Promotor, Exon 1 und Intron-Enhancer des CD95-Gens von 17 Tumorproben mit Ras-Mutationen (KRAS2-Mutation in Kodon 12) mittels methylierungssensitiver Restriktionsenzyme, nachfolgendem Southernblot und Hybridisierung ermittelt. Bei 16 Tumoren erbrachte die Restriktionsanalyse für Sma I ein Restriktionsmuster, das eine Methylierung der Cytosine der CCCGGG-Motive im genannten Bereich ausschließt. Die nicht geschnittene Sma I-Sequenz in einer Tumor-DNA (Position 143901) wurde auch für die Normal-DNA nachgewiesen und erwies sich als RFLP. Ein aufgrund dieses Ergebnisses postulierter Polymorphismus innerhalb einer Sma I- Schnittstelle konnte durch Sequenzierung der isolierten Sequenz aus dem entsprechenden Tumor verifiziert werden. Möglicherweise ist die Entstehung dieses Polymorphismus zwar die Folge einer ehemaligen Methylierung des Cytosins in der Konstellation CpG; allerdings konnte nachgewiesen werden, daß der entsprechende Nukleotidaustausch nicht im Rahmen der Karzinogenese erfolgt war, da die DNA aus PBL des gleichen Patienten die identische Sequenz aufwies. Insgesamt wurde somit für keinen der untersuchten Tumoren eine Abschaltung der CD95-Expression aufgrund einer Methylierung des Gens durch aktiviertes, onkogenes Ras festgestellt.
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