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Tim Spellman discusses his paper, “An Open-Source 3D-Printable Platform for Testing Head-Fixed Cognitive Flexibility in Rodents,” with Reviewing Editor Mark Laubach. Spellman and Laubach also discuss the bigger picture benefits of sharing open-source tools and data for reproducibility and for cost-effective solutions that any lab can use. Find our upcoming webinar schedule here. With special guest: Tim Spellman Hosted by: Mark Laubach On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Karl Herrup, Michelle Jin, and James Noble share their perspectives on evaluating the clinical impacts of emerging treatments for Alzheimer's Disease with eNeuro Editor-in-Chief Christophe Bernard. Find our upcoming webinar schedule here. With special guests: Karl Herrup, Michelle Jin, and James Noble Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Yizhou Lyu, Zishan Su, and Yuan Chang Leong discuss their paper, “Hostile Attribution Bias Shapes Neural Synchrony in the Left Ventromedial Prefrontal Cortex during Ambiguous Social Narratives,” published in Vol. 44, Issue 9 of JNeurosci, with JNeurosci Reviewing Editor Daniela Schiller. Find our upcoming webinar schedule here. With special guests: Yizhou Lyu, Zishan Su, and Yuan Chang Leong Hosted by: Daniela Schiller On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
This year, eNeuro is celebrating 10 years of publishing by highlighting select papers from throughout its history. This episode features a 2018 paper titled “Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats” and showcases interviews with Olivier George and Jenni Kononoff. Find out more information about SfN's Reviewer Mentor Program. With special guests: Olivier George and Jenni Kononoff Hosted by: Christophe Bernard and Rosalind Carney On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Anthony Burgos-Robles and Ada Felix-Ortiz discuss their paper, “Prefrontal Regulation of Safety Learning during Ethologically Relevant Thermal Threat,” published in Vol. 11, Issue 2 of eNeuro, with Editor-in-Chief Christophe Bernard. Find our upcoming webinar schedule here. With special guests: Anthony Burgos-Robles and Ada Felix-Ortiz Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Welcome to the (delayed) 10th & SUMMER BOTOX SPECIAL EPISODE of BSCOS Paediatric Orthopaedic Digest (POD)cast with Caroline Edwards, Head of Childrens Surgery at Plymouth hospital who started her consultant career at Southampton Childrens Hospital, she set up and developed the neuromuscular service. She proposes a "hub and spoke" model for learning at busy tertiary centres and shared her research on the surgical vulnerability score, a tool to assess the likelihood of early death in patients with neuromuscular disorders. Caroline highlights the challenges faced by young adults transitioning from clinic care for cerebral palsy and suggested district general hospitals could provide dedicated clinics. Listen in to the episode to learn more! We scoured 35 journals & highlighted the most impactful studies that we feel can change practice or improve outcomes in Paediatric Orthopaedics. Follow Updates on @BSCOS_UK REFERENCES: 1. Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril. Howard JJ & Herzog W. Front Neurol. Feb 2021. PMID: 33679586 2. Virtual Reality Distraction Is No Better Than Simple Distraction Techniques for Reducing Pain and Anxiety During Pediatric Orthopaedic Outpatient Procedures: A Randomized Controlled Trial. Fabricant PD et al. Clin Orthop Relat Res. May 2024. PMID: 37939199 3. Effect of parental touch on relieving acute procedural pain in neonates and parental anxiety (Petal): a multicentre, randomised controlled trial in the UK. Hauck AGV et al. Lancet Child Adolesc Health. April 2024. PMID: 38373429. 4. REM Sleep Preserves Affective Response to Social Stress-Experimental Study. Halonen et al. eNeuro. June 2024. PMID: 38802242 5. Functional electrical stimulation during walking in children with unilateral spastic cerebral palsy: A randomized cross-over trial. Moll et al. Dev Med Child Neurol. May 2024. PMID: 37823431. 6. Clinical Effectiveness of Newborn Screening for Spinal Muscular Atrophy: A Nonrandomized Controlled Trial. Schwartz et al. JAMA Pediatr. June 2024. PMID: 38587854 7. Surgical management of proximal femoral unicameral bone cyst in children. Maximen et al + SOFOP. Bone Joint J. May 2024. PMID: 38688504 8. Treatment of Hip Displacement in Children With Cerebral Palsy: A 5-year Comparison of Proximal Femoral Osteotomy and Combined Femoral-Pelvic Osteotomy in 163 Children. Kiapekos N et al. J Pediatr Orthop. July 2024. PMID: 38477355 9. Impact of Pavlik Harness treatment on motor skills acquisition: A case-control study. Jesus AR et al. J Child Orthop. March 2024. PMID: 39100978 10. Deep Learning Analysis of Surgical Video Recordings to Assess Nontechnical Skills. Harari RE et al. JAMA Netw Open. July 2024. PMID: 39083274 11. Single versus double retrograde intramedullary nail technique for treatment of displaced proximal humeral fractures in children: A retrospective cohort study. Samara E et al. J Child Orthop. March 2024. PMID: 38831859 12. Can the Achilles tendon regenerate completely following percutaneous tenotomy in older children with clubfoot? Aroojis A et al. Int Orthop. June 2024. PMID: 38340143. 13. Guided Growth With Minifragment Plates for Angular Deformities in the Distal Radius in Skeletally Immature Patients. Preliminary Results. Soler-Jimenez A et al. J Pediatr Orthop. September 2024. PMID: 38767293. 14. Robot-assisted Temporary Hemiepiphysiodesis With Eight-plates for Lower Extremity Deformities in Children. Liang M et al. J Pediatr Orthop. April 2024. PMID: 38312109 Follow Hosts: @AnishPSangh @AlpsKothari @Pranai_B See as many of you as possible at the BSCOS sessions at the BOA in Birmingham!
Mary Kate Joyce discusses her paper, “Subgenual and Hippocampal Pathways in Amygdala Are Set to Balance Affect and Context Processing,” published in Vol. 43, Issue 17 of JNeurosci in 2023, with Megan Sansevere from SfN's Journals' staff. Find the rest of the Spotlight collection here. With special guest: Mary Kate Joyce Hosted by: Megan Sansevere On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Emilia Lefevre discusses her paper, “Differential Patterns of Synaptic Plasticity in the Nucleus Accumbens Caused by Continuous and Interrupted Morphine Exposure,” published in Vol. 43, Issue 2 of JNeurosci in 2023, with Megan Sansevere from SfN's Journals' staff. Find the rest of the Spotlight collection here. With special guest: Emilia Lefevre Hosted by: Megan Sansevere On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
This year eNeuro is celebrating 10 years of publishing by highlighting select papers from throughout its history. This episode features a 2018 paper titled, "RNA from Trained Aplysia Can Induce an Epigenetic Engram for Long-Term Sensitization in Untrained Aplysia," and showcases interviews with David Glanzman and Alexei Bédécarrats. With special guests: David Glanzman and Alexei Bédécarrats Hosted by: Christophe Bernard and Rosalind Carney On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
Does samba lift your mood? How about karaoke or playing a guitar? Does music feed your soul? Scaachi and Sophia hear how music can make you feel alive and affect sleep quality, mental alertness, and memory. They find out about free lessons in Finland and the power of music in Brazil. It's time to start singing, play an instrument or sit back and listen and pretend you are in a music video – that's what Sophia likes doing on a train. Guests: Doctor of education Liisa-Maria Lilja-Viherlampi and Brazilian Voices founder Loren Oliveira. Let us know what you think. Share your thoughts on this episode and suggest ideas for a new one by sending us a voice note on WhatsApp: +44330 123 9459 For more information: The Powerful Impact Of Music- Neuroscience of music ( Stanford): https://ojs.stanford.edu/ojs/index.php/intersect/article/view/2873 World Happiness Report: https://worldhappiness.report/ed/2024/happiness-of-the-younger-the-older-and-those-in-between/#ranking-of-happiness-2021-2023 Vocal Music Listening Enhances Poststroke Language Network Reorganization: https://www.eneuro.org/content/8/4/ENEURO.0158-21.2021#ref-80 Scoping review of how music affects physicality: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455907/
We know that the quality of the sleep we get at night sleep has a strong impact on our waking lives. However, what we don't know is how the different sleep stages contribute to how we process life experiences and memories. New research out this week in the journal eNeuro has used an unusual method to try and understand this more. Our sleep consists of different stages that help us to process our day. Deep sleep, also known as slow wave sleep (SWS) is associated with memory consolidation and helps to make our memories longer lasting. Rapid eye movement (REM) sleep is the period of sleep where we dream and consolidate our memories. It is less well understood, but thought to be associated with the way that we process emotions and how we remember experiences that are more emotionally charged. To try and understand this better, scientists took 29 volunteers and asked them to sing Abba's Dancing Queen on karaoke while wearing headphones that meant they couldn't hear their own voice. They then took this recording of their singing, removed the background music and played the out-of-tune singing back to the volunteer right before bedtime. The volunteers reported feeling embarrassed when they heard the recording. The volunteers then went to sleep while being monitored and the researchers woke them up during the night either during their SWS or their REM sleep stage. The volunteers were then replayed the bad singing tape the next morning after their disrupted sleep and 5 days later. Every time they were played the tape, the scientists measured the physiological stress response of the volunteers through a skin conductance level test and measured their reported stress level through a subjective embarrassment rating test. The researchers found that the volunteers who had been disrupted during their SWS sleep phase but kept their REM sleep intact had higher measured stress levels every time they listened to their embarrassing tape compared to those who were disrupted during their REM stage. They concluded that the REM stage of sleep plays a crucial role in preserving and even strengthening how emotionally charged a stressful memory is. The study could help those suffering from anxiety disorders to use sleep therapy that disrupts their REM stages of sleep to help them to reduce some of their negative emotions. LISTEN ABOVESee omnystudio.com/listener for privacy information.
Keshov Sharma and Lizabeth Romanski discuss their paper, “Neuronal Population Encoding of Identity in Primate Prefrontal Cortex,” published in Vol. 44, Issue 6 of JNeurosci, with Editor-in-Chief Cabine Kastner. Find our upcoming webinar schedule here. With special guests: Keshov Sharma and Lizabeth Romanski Hosted by: Sabine Kastner On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on X, Instagram, and LinkedIn.
In this episode, the Editors-in-Chief of the Journal of Neuroscience and eNeuro, Sabine Kastner and Christophe Bernard, discuss the importance of peer review and the progressive review models they have worked to implement at their respective journals. Both agree that, while imperfect, peer review is still a valuable part of the research process. Listen to their conversation to learn how their personal experiences as authors and reviewers shaped their decisions as editors. With special guests: Sabine Kastner and Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
JNeurosci Reviewing Editors Bruno Averbeck and Anne-Marie Oswald discuss best practices for writing computational neuroscience papers for The Journal of Neuroscience. They offer tips and strategies for how to organize the paper and clearly present technical material to the broad neuroscience community that is the readership of the journal. To see the example figures mentioned in this episode, view this webinar on-demand. With special guests: Bruno Averbeck and Anne-Marie Oswald On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Anan Moran and Elor Arieli discuss their paper, “Distinct Progressions of Neuronal Activity Changes Underlie the Formation and Consolidation of a Gustatory Associative Memory,” published in Vol. 42, Issue 5 of JNeurosci, with Megan Sansevere from SfN's Journals' staff. Find the rest of the Spotlight collection here. With special guests: Anan Moran and Elor Arieli Hosted by: Megan Sansevere On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Julie-Anne Balouek and Catherine Jensen Peña discuss their paper, “Reactivation of Early-Life Stress-Sensitive Neuronal Ensembles Contributes to Lifelong Stress Hypersensitivity,” published in Vol. 43, Issue 34 of JNeurosci, with reviewing editor Mary Kay Lobo. Find our upcoming webinar schedule here. With special guests: Julie-Anne Balouek and Catherine Jensen Peña Hosted by: Mary Kay Lobo On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Laia Fibla and John Spencer discuss their paper, “Language exposure and brain myelination in early development”, published in Vol. 43, Issue 23 of JNeurosci, with Reviewing Editor Elana Zion-Golumbic. Find our upcoming webinar schedule here. With special guests: Laia Fibla and John Spencer On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Congying Chu and David Elmenhorst discuss their paper, “Total Sleep Deprivation Increases Brain Age Prediction Reversibly in Multisite Samples of Young Healthy Adults,” published in Vol. 43, Issue 12 of JNeurosci, with Editor-in-Chief Sabine Kastner. Find our upcoming webinar schedule here. With special guests: Congying Chu and David Elmenhorst Hosted by: Sabine Kastner On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Kaitlin Laws and Greg Bashaw discuss their paper, “DrosoPHILA: A Partnership between Scientists and Teachers That Begins in the Lab and Continues into City Schools,” published in Vol. 10, Issue 2 of eNeuro, with BrainFacts editor Kelley Remole. Find our upcoming webinar schedule here. With special guests: Kaitlin Laws and Greg Bashaw Hosted by: Kelley Remole On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Terry Dean and Vittorio Gallo discuss their paper, “Endogenous Circadian Clock Machinery in Cortical NG2-Glia Regulates Cellular Proliferation,” published in Vol. 9, Issue 5 of eNeuro, with Editor-in-Chief Cristophe Bernard. Find our upcoming webinar schedule here. With special guests: Terry Dean and Vittorio Gallo Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Larry Squire and Tom Albright, coeditors of The History of Neuroscience in Autobiography book series, talk about their work collecting the personal narratives from researchers who have contributed to the field of neuroscience, and why this collection of stories is an important component of the historical record. History of Neuroscience in Autobiography book series Autobiographical videos of prominent neuroscientists With special guests: Larry Squire and Tom Albright Hosted by: Blythe Alexander and Taylor Johnson On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
In 2019, SfN published the History of Society for Neuroscience: 50th Anniversary podcast series. One guest was Dr. Marina Picciotto, who just finished her 7-year tenure as Editor-in-Chief at JNeurosci and is now the President-Elect of SfN. We hope you'll enjoy this lightly edited version of her interview from 2019 as she reflects on the launch, growth, and future of JNeurosci. With special guest: Marina Picciotto Hosted by: Taylor Johnson On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Marina Picciotto (outgoing JNeurosci Editor-in-Chief and SfN President-Elect) and Sabine Kastner (incoming JNeurosci Editor-in-Chief) discuss their careers along with the history and future of The Journal of Neuroscience. Check out the Reviewer Mentor Program. With special guests: Marina Picciotto and Sabine Kastner Hosted by: Blythe Alexander On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Neste vídeo eu vou falar do papel da Insulina na recuperação do olfato e paladar, das vitaminas e minerais que podem auxiliar, plantas e ervas e também explicar como fazer o treinamento olfativo que já ajudou milhares de pessoas a recuperar o olfato pós vírus. Seja membro deste canal e ganhe benefícios, conteúdo exclusivo, acesso ao grupo de Whatsapp e 2 lives exclusivas mensais: https://www.youtube.com/channel/UCRLKi_9gQNthwlKi70qi54g/join Conheça a Pós Graduação do Dr Alain - https://alaindutra.com/apoia Links Artigo insulina de neurônios sensoriais olfativos : https://www.eneuro.org/content/8/3/ENEURO.0168-21.2021 https://www.youtube.com/watch?v=KNDNgPa4pbQ https://clinicaltrials.gov/ct2/show/study/NCT04406584 https://www.youtube.com/watch?v=AfkOp2o47Wg Jejum: https://www.youtube.com/watch?v=PdIPah7sMc8 https://www.youtube.com/watch?v=BQQ4kbX417o https://youtu.be/MH-_FHA18e4 Capítulos - TimeStamp 0:00 Introdução 1:31 outras causas para perda de olfato e paladar 2:21 O papel da Insulina 4:06 spray de insulina 4:33 Revertendo a resistência a insulina 5:48 Não sou diabético e tenho perda de olfato 6:25 Melhorando a resistência a insulina 7:14 Minerais e vitaminas 8:54 Treinamento olfativo 10:24 PRP 10:47 Ervas e suplementos ⚠️AVISO LEGAL⚠️ A informação médica contida nesse vídeo é somente para fins de informação geral e não deve ser usada para qualquer finalidade de diagnóstico ou tratamento. Esta informação NÃO cria nenhuma relação médico-paciente e não deve ser usado como substituto de diagnóstico ou tratamento profissional. Por favor, consulte seu médico antes de tomar qualquer decisão sobre cuidados de saúde e NÃO pare nenhuma medicação sem o consentimento do seu médico. A Medicina é uma ciência em constante mudança, os vídeos são produzidos baseados nos Artigos Científicos mais recente até a data. De acordo com Art. 8º da Resolução CFM 1974/11 de Publicidade do Código de Ética Médica, os vídeos têm somente caráter de prestar informações de fins estritamente educativos. Dr. Alain Dutra -
Ranier Gutierrez discusses his paper, “Optoception: Perception of Optogenetic Brain Perturbations,” published in Vol. 9, Issue 3 of eNeuro, with Editor-in-Chief Christophe Bernard. Find our upcoming webinar schedule here. With special guest: Ranier Gutierrez Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
In this episode of Mommy Brain Revisited I talk with Dr. Amanda Kentner a Full Professor at Massachusetts College of Pharmacy and Health Sciences in the USA. We talk about her recent research published at eNeuro on the important role that enrichment can play in parenting and development. Don't miss this episode on cutting edge research in behavioral neuroscience. So interesting! Download the publication here: https://www.eneuro.org/content/9/4/ENEURO.0148-22.2022 For more information about Prof. Kentner's research see https://www.kentnerlab.org/ Citations: DeRosa H, Caradonna SG, Tran H, Marrocco J, Kentner AC. Milking It for All It's Worth: The Effects of Environmental Enrichment on Maternal Nurturance, Lactation Quality, and Offspring Social Behavior. eNeuro. 2022 Aug 25;9(4):ENEURO.0148-22.2022. doi: 10.1523/ENEURO.0148-22.2022. PMID: 35995560. Follow @dr.jodi_pawluski on instagram for more on how the brain changes with parenting. https://www.jodipawluski.com/ --- Support this podcast: https://anchor.fm/mommybrainrevisited/support
Felix Schneider discusses his paper, “Neuron Replating, a Powerful and Versatile Approach to Study Early Aspects of Neuron Differentiation,” published in Vol. 8, Issue 3 of eNeuro, with Editor-in-Chief Christophe Bernard. Find our upcoming webinar schedule here. With special guest: Felix Schneider Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Candler Paige and Ted Price discuss their paper, “A Female-Specific Role for Calcitonin Gene-Related Peptide (CGRP) in Rodent Pain Models,” published in Vol. 42, Issue 10 of JNeurosci, with Editor-in-Chief Marina Picciotto. Find our upcoming webinar schedule here. With special guests: Candler Paige and Ted Price Hosted by: Marina Picciotto On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Matthew Colonnese discusses his paper, “Input-Independent Homeostasis of Developing Thalamocortical Activity,” published in Vol. 8, Issue 3 of eNeuro, with Editor-in-Chief Christophe Bernard. Find our upcoming webinar schedule here. Hosted by: Christophe Bernard On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
Authors Paula Celeste Salamone and Agustín Ibáñez discuss their paper, “Interoception Primes Emotional Processing: Multimodal Evidence from Neurodegeneration,” published in Vol. 41, Issue 19 of the Journal of Neuroscience, with Editor-in-Chief Marina Picciotto. Find our upcoming webinar schedule here. On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn. Hosted by: Marina Picciotto
"The question before us then is what can be done to reduce the burden that these fallacies place on the field; what is our path forward?" — Karl Herrup, Fallacies in Neuroscience: The Alzheimer's Edition. "A fallacious argument is one that seems to be valid but is not so. Why are fallacies so commonplace in scientific papers, and why can we not detect them when we read them?" — Christophe Bernard, On Fallacies in Neuroscience. In this episode, Karl Herrup and Christophe Bernard explore how logical fallacies and unseen bias limit scientific advancement in their fields of Alzheimer's disease and epilepsy. Read more papers in eNeuro's ongoing series on Experimental Bias. On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn. Hosted by: Christophe Bernard
Listen to this interview of Christophe Bernard, Director of Research at INSERM and Editor-in-Chief of eNeuro. We talk about the review process, about education in the sciences, and again a little bit more about education in the sciences. Christophe Bernard : "Science is everything that a scientist does. But for many people, science is only the bench work — to them, that's what a scientist really does. And the publishing part — well, that's just something that others do. Even the review process, for too many people, is just not fully integrated into the work that scientists are doing. But there should not be a barrier between doing science and reviewing science. It should be the same world — a continuity between the two. Now, in institutions, they focus all their efforts on teaching people how to do science. But doing science also is knowing how to review a paper. Perhaps you know, but there is a crisis in the reviewing process. Many authors have commented on being mistreated by reviewers, and although there'll be many reasons why that happens, the main reason is that we are not taught how to review a paper. And this just leads to frustration, or worse, because when you're an author and you submit a paper and you receive comments which are aggressive and do not make sense and are just plain unhelpful, then you start to distrust the system." Watch Daniel edit your science here. Contact Daniel at writeyourresearch@gmail.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
Listen to this interview of Christophe Bernard, Director of Research at INSERM and Editor-in-Chief of eNeuro. We talk about the review process, about education in the sciences, and again a little bit more about education in the sciences. Christophe Bernard : "Science is everything that a scientist does. But for many people, science is only the bench work — to them, that's what a scientist really does. And the publishing part — well, that's just something that others do. Even the review process, for too many people, is just not fully integrated into the work that scientists are doing. But there should not be a barrier between doing science and reviewing science. It should be the same world — a continuity between the two. Now, in institutions, they focus all their efforts on teaching people how to do science. But doing science also is knowing how to review a paper. Perhaps you know, but there is a crisis in the reviewing process. Many authors have commented on being mistreated by reviewers, and although there'll be many reasons why that happens, the main reason is that we are not taught how to review a paper. And this just leads to frustration, or worse, because when you're an author and you submit a paper and you receive comments which are aggressive and do not make sense and are just plain unhelpful, then you start to distrust the system." Watch Daniel edit your science here. Contact Daniel at writeyourresearch@gmail.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience
Listen to this interview of Christophe Bernard, Director of Research at INSERM and Editor-in-Chief of eNeuro. We talk about the review process, about education in the sciences, and again a little bit more about education in the sciences. Christophe Bernard : "Science is everything that a scientist does. But for many people, science is only the bench work — to them, that's what a scientist really does. And the publishing part — well, that's just something that others do. Even the review process, for too many people, is just not fully integrated into the work that scientists are doing. But there should not be a barrier between doing science and reviewing science. It should be the same world — a continuity between the two. Now, in institutions, they focus all their efforts on teaching people how to do science. But doing science also is knowing how to review a paper. Perhaps you know, but there is a crisis in the reviewing process. Many authors have commented on being mistreated by reviewers, and although there'll be many reasons why that happens, the main reason is that we are not taught how to review a paper. And this just leads to frustration, or worse, because when you're an author and you submit a paper and you receive comments which are aggressive and do not make sense and are just plain unhelpful, then you start to distrust the system." Watch Daniel edit your science here. Contact Daniel at writeyourresearch@gmail.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
Listen to this interview of Christophe Bernard, Director of Research at INSERM and Editor-in-Chief of eNeuro. We talk about the review process, about education in the sciences, and again a little bit more about education in the sciences. Christophe Bernard : "Science is everything that a scientist does. But for many people, science is only the bench work — to them, that's what a scientist really does. And the publishing part — well, that's just something that others do. Even the review process, for too many people, is just not fully integrated into the work that scientists are doing. But there should not be a barrier between doing science and reviewing science. It should be the same world — a continuity between the two. Now, in institutions, they focus all their efforts on teaching people how to do science. But doing science also is knowing how to review a paper. Perhaps you know, but there is a crisis in the reviewing process. Many authors have commented on being mistreated by reviewers, and although there'll be many reasons why that happens, the main reason is that we are not taught how to review a paper. And this just leads to frustration, or worse, because when you're an author and you submit a paper and you receive comments which are aggressive and do not make sense and are just plain unhelpful, then you start to distrust the system." Watch Daniel edit your science here. Contact Daniel at writeyourresearch@gmail.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system.
Want to know how we work well in teams? Then listen in to the latest episode exploring team flow with Professor Mohammed Shehata. Flow is our ability to enter that state where everything aligns and we are able to focus entirely on the task at hand. - The eNeuro paper (the journal article here) News coverage including The Times Magazine London (here), Psychology Today (here and here), IFL Science (here), TVN (here), Science Alert (here), SciShow News (here), and more (here). - Mohammad Shehata's LinkedIn - Mohammad Shehata's Twitter :@Mohamma_Shehata
Here's what recent research has to say about restoring your sense of smell. DATA: https://www.eneuro.org/content/8/3/ENEURO.0168-21.2021 D3 & K2 VITAMIN: https://bit.ly/3w8aJ00 NUTRITIONAL YEAST (B VITAMINS): https://bit.ly/2Y6Y3Kb FREE COURSE ➜ ➜ https://courses.drberg.com/product/how-to-bulletproof-your-immune-system/ FREE MINI-COURSE ➜ ➜ Take Dr. Berg's Free Keto Mini-Course! ADD YOUR SUCCESS STORY HERE: https://bit.ly/3z9TviS Talk to a Dr. Berg Keto Consultant today and get the help you need on your journey (free consultation). Call 1-540-299-1557 with your questions about Keto, Intermittent Fasting, or the use of Dr. Berg products. Consultants are available Monday through Friday from 8 AM to 10 PM EST. Saturday & Sunday from 9 AM to 6 PM EST. USA Only. Dr. Eric Berg DC Bio: Dr. Berg, 51 years of age is a chiropractor who specializes in weight loss through nutritional & natural methods. His private practice is located in Alexandria, Virginia. His clients include senior officials in the U.S. government & the Justice Department, ambassadors, medical doctors, high-level executives of prominent corporations, scientists, engineers, professors, and other clients from all walks of life. He is the author of The 7 Principles of Fat Burning. Dr. Berg's Website: http://bit.ly/37AV0fk Dr. Berg's Recipe Ideas: http://bit.ly/37FF6QR Dr. Berg's Reviews: http://bit.ly/3hkIvbb Dr. Berg's Shop: http://bit.ly/3mJcLxg Dr. Berg's Bio: http://bit.ly/3as2cfE Dr. Berg's Health Coach Training: http://bit.ly/3as2p2q Facebook: https://www.facebook.com/drericberg Messenger: https://www.messenger.com/t/drericberg Instagram: https://www.instagram.com/drericberg/ YouTube: http://bit.ly/37DXt8C
Meet Confident Human Sierra Simpson—a a scientist with a PhD in Neuroscience, a published author, artist, and founder of Brilliant Biome. She is changing the world as we know it when it comes to the understanding of our microbiome and the integral role it plays in our overall health. In a study published April 27, 2020 in eNeuro, Simpson and team discovered that the gut microbiome influences the pattern of activation in a rat's brain during opioid addiction and withdrawal. Sierra's methodology of "hitting the problem with a hammer to see how the system breaks, then backtrack from there" makes her tenacity to solve problems unparalleled. How her dedication to making science for everyone has made her approachable and a true leader. In this episode we talk about the microbiome(s) and its importance; the gut-brain connection; the gut-skin axis; and all things science in a digestible format. https://www.theconfidence.co/blogs/community/confident-human-sierra-simpson Read a full interview with Sierra on our blog www.theconfidence.co more info on The Confidence Co www.theconfidence.co with CH10 get 10% off your first purchase
You're listening to the March episode of 3 Minute 3Rs.The papers behind the pod:1. Novel three-dimensional biochip pulmonary sarcoidosis model. PLoS One https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0245805 2. A new group housing approach for non-human primate metabolism studies. Journal of Pharmacological and Toxicological Methods https://doi.org/10.1016/j.vascn.2020.1069473. The contribution of environmental enrichment to phenotypic variation in mice and rats. eNeuro https://doi.org/10.1523/ENEURO.0539-20.2021Transcript: It's the 3rd Thursday of March and you're listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. This month, we've got two refinements to cover – a paper for primates and one for rodents too. But first, let's have some lung chips. [NC3Rs]Despite being first described towards the end of the 19th century, a lot about sarcoidosis remains unknown. The granulomas characteristic of the disease can affect almost any organ in the body, but the lung is most commonly affected, and associated with the highest morbidity and mortality in patients. Pulmonary granulomas can be modelled in animals, but as there is no known specific genetic component, transgenic animals representing the human condition cannot be easily created. Instead, animals are typically pre-sensitised to environmental agents, such as bacteria, and then repeatedly exposed to the same antigens to form granulomas.Using organ-on-a-chip technology, Calcagno et al introduced granulomas, isolated from patient blood samples, to its air-lung interface. They were able to detect macrophages and lymphocytes from the developed granulomas in the interface and inflammatory cytokines being released into the culture media. As well as better understanding the mechanisms behind sarcoidosis, the system can also be used to develop new treatments, with high-throughput potential and AI compatibility. You can read more about the method by following the link in the description.Next up, thinking beyond single housing[NA3RsC] Before new drugs are approved by regulatory bodies, they must undergo testing to understand their absorption, distribution, metabolism, and excretion. This is a key step in assuring their safety and efficacy. Sometimes, when there is no scientific alternative, non-human primates are used for these tests.Traditionally, for metabolism studies animals are singly-housed in cages that limit normal vertical movement & social behaviors which negatively impacts welfare. However, recently, Novo Nordisk, Covance, & other collaborators worked together to design a refined group housing metabolism cage. This cage has extensive advantages such as more space, better socialization, and less stress. Importantly, excretion data from this cage is comparable to the singly housed cages which supports its suitability for future metabolism studies.To read more, see the full paper online.And finally, a reminder that enrichment is a good thing. [LA] Researchers often to want to control as many variables as they can in their experiments. However, providing environmental enrichment is beneficial for the welfare of... See acast.com/privacy for privacy and opt-out information.
Tulling, M., Law, R., Cournane, A., & Pylkkänen, L. (2021). Neural correlates of modal displacement and discourse-updating under (un)certainty. eNeuro, 8(1). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810261/ Transcript: https://wp.nyu.edu/neurolinglab/nellabspotlight_ep2-maxime-tulling/ Linguistics, semantics, neurolinguistics, discourse processing
Aaron is a cognitive neuroscientist, working on volition and consciousness. Aaron and I met in 2016 in Paris when I did my MSc thesis in his lab at Neurospin on decoding planned and spontaneous movements, using M/EEG. Aaron has since moved to California where he is Assistant Professor at Chapman University.In this conversation, we talk about Aaron's work in trying to understand the readiness potential. We talk about the classic interpretation, Aaron's interpretation, and how Aaron's interpretation can be applied to non-movement contexts, including the stock market and meteorology.Time stamps0:00:40 We don't really know what the readiness potential is0:01:52 The classic interpretation of the readiness potential0:16:39 Aaron's interpretation of the readiness potential0:31:04 The origin of Aaron's interpretation0:42:33 Applying Aaron's model to non-movement contexts: the stock market and meteorology0:54:40 - Aaron's plans for studying the readiness potential in the next few years: breathing, individual differences, anticipationLinksPodcast linksWebsite: https://bjks.buzzsprout.com/ Twitter: https://twitter.com/BjksPodcastAaron's links Chapman profile: https://www.chapman.edu/our-faculty/aaron-schurgerGoogle Scholar: https://scholar.google.de/citations?user=lBSjfagAAAAJ&hl=en&oi=sraTwitter: https://twitter.com/schurgerlabBen's links: Website: https://bjks.blog/Google Scholar: https://scholar.google.de/citations?user=-nWNfvcAAAAJ&hl=en&oi=aoPapers mentionedFried, I., Mukamel, R., & Kreiman, G. (2011). Internally generated preactivation of single neurons in human medial frontal cortex predicts volition. NeuronKagaya, K., & Takahata, M. (2010). Readiness discharge for spontaneous initiation of walking in crayfish. Journal of NeuroscienceKornhuber, H. H., & Deecke, L. (1965/2016). Hirnpotentialänderungen bei Willkürbewegungen und passiven Bewegungen des Menschen: Bereitschaftspotential und reafferente Potentiale/Brain potential changes in voluntary and passive movements in humans: readiness potential and reafferent potentials. Pflüger's ArchivLibet, B., Gleason, C. A., Wright, E. W., & Pearl, D. K. (1983). Time of conscious intention to act in relation to onset of cerebral activity. BrainSchotanus, P., & Schurger, A. (2020). Spontaneous Volatility: Fooled by Reflexive Randomness. Journal of Behavioral FinanceSchurger, A., Sitt, J. D., & Dehaene, S. (2012). An accumulator model for spontaneous neural activity prior to self-initiated movement. Proceedings of the National Academy of SciencesSchurger, A., Mylopoulos, M., & Rosenthal, D. (2016). Neural antecedents of spontaneous voluntary movement: a new perspective. Trends in Cognitive SciencesSchurger, A. (2018). Specific relationship between the shape of the readiness potential, subjective decision time, and waiting time predicted by an accumulator model with temporally autocorrelated input noise. Eneuro
El cerebro está hecho de células, pero para entenderlo hace falta comprender su química y también su electricidad. Neuronas chisporroteantes, dirían algunos. Pues eso es exactamente lo que hacen los expertos en electrofisiología. ¿Cómo puede una neurona producir electricidad? ¿Son las únicas células capaces de hacerlo? ¿Cómo conseguimos medir esas descargas eléctricas? ¿Podemos utilizar ese conocimiento para comunicarnos con nuestro cerebro usando electricidad? Las respuestas son fascinantes, porque abren un mundo de posibilidades y dan a la neurociencia un saber diferente al de otras ciencias de carácter biológico. Hablemos de nuestro cerebro, un cerebro eléctrico.Para ello tenemos con nosotros a Liset Menéndez de la Prida, que es graduada en Física, doctora en Neurociencias. Además, ha sido editora del Journal of Neuroscience, Journal of Neuroscience Methods y eNeuro y ha formado parte de los cargos de American Epilepsy Society, la Sociedad Española de Neurociencias y la Sociedad Española de Epilepsia. Actualmente lidera el Laboratorio de Circuitos Neuronales en el Instituto Cajal en Madrid y, por si fuera poco, a sus publicaciones científicas se suma un libro de divulgación del que es autora: La Neurociencia del Espacio y el Tiempo.
The Gary Null Show is here to inform you on the best news in health, healing, the environment. Antioxidant-rich powders from blueberry, persimmon waste could be good for gut microbiota Polytechnic University of Valencia (Italy), July 24, 2020 Feeding the world's growing population in a sustainable way is no easy task. That's why scientists are exploring options for transforming fruit and vegetable byproducts -- such as peels or pulp discarded during processing -- into nutritious food ingredients and supplements. Now, researchers reporting in ACS' Journal of Agricultural and Food Chemistry have shown that blueberry and persimmon waste can be made into antioxidant-rich powders that might have beneficial effects on gut microbiota. In recent years, fruit and vegetable powders have become popular as a way to add beneficial compounds, such as polyphenols and carotenoids (two types of antioxidants), to the diet, either by consuming the powders directly or as an ingredient in food products. However, in many cases these healthful compounds are present at similar or even higher levels in byproducts compared to those in other parts of the fruit or vegetable. Noelia Betoret, María José Gosalbes and colleagues wanted to obtain powders from persimmon and blueberry wastes, and then study how digestion could affect the release of antioxidants and other bioactive compounds. They also wanted to determine the effects of the digested powders on gut bacterial growth. The researchers obtained powders from persimmon peels and flower parts, and from the solids left behind after making blueberry juice. The type of powder, drying method, fiber content and type of fiber determined the release of antioxidants during a simulated digestion. For example, freeze-drying preserved more anthocyanins, but these were more easily degraded during digestion than those in air-dried samples. Then, the team added the powders to a fecal slurry and conducted a mock colonic fermentation, sequencing the bacteria present before and after fermentation. Incubation with the fruit powders resulted in an increase in several types of beneficial bacteria, and some bacteria grew better with one powder compared to the other. These findings indicate that persimmon and blueberry waste powders could be included in food formulations to boost the content of carotenoids and anthocyanins, which could have a positive impact on human health, the researchers say. Plant-based diets shown to lower blood pressure even with limited meat and dairy Consuming a plant-based diet can lower blood pressure even if small amounts of meat and dairy are consumed too, according to new research University of Warwick (UK), July 27, 2020 Consuming a plant-based diet can lower blood pressure even if small amounts of meat and dairy are consumed too, according to new research from the University of Warwick. Published online by a team from Warwick Medical School in the Journal of Hypertension today (25 July), they argue that any effort to increase plant-based foods in your diet and limit animal products is likely to benefit your blood pressure and reduce your risk of heart attacks, strokes and cardiovascular disease. They conducted a systematic review of previous research from controlled clinical trials to compare seven plant-based diets, several of which included animal products in small amounts, to a standardised control diet and the impact that these had on individuals' blood pressure. Plant-based diets support high consumption of fruits, vegetables, whole grains, legumes, nuts and seeds, limiting the consumption of most or all animal products (mainly meat and diary). (See Notes to Editors for further details) High blood pressure is the leading risk factor globally for heart attacks, strokes and other cardiovascular diseases. A reduction in blood pressure has important health benefits both for individuals and for populations. Unhealthy diets are responsible for more deaths and disabilities globally than tobacco use, high alcohol intake, drug use and unsafe sex put together. An increased consumption of whole grains, vegetables, nuts and seeds, and fruit, as achieved in plant-based diets, could avert up to 1.7, 1.8, 2.5 and 4.9 million deaths globally respectively every year according to previous research. Vegetarian and vegan diets with complete absence of animal products are already known to lower blood pressure compared to omnivorous diets. Their feasibility and sustainability are, however, limited. Until now, it has not been known whether a complete absence of animal products is necessary in plant-based dietary patterns to achieve a significant beneficial effect on blood pressure. Lead author Joshua Gibbs, a student in the University of Warwick School of Life Sciences, said: "We reviewed 41 studies involving 8,416 participants, in which the effects of seven different plant-based diets (including DASH, Mediterranean, Vegetarian, Vegan, Nordic, high fibre and high fruit and vegetables) on blood pressure were studied in controlled clinical trials. A systematic review and meta-analysis of these studies showed that most of these diets lowered blood pressure. The DASH diet had the largest effect reducing blood pressure by 5.53/3.79 mmHg compared to a control diet, and by 8.74/6.05 mmHg when compared to a 'usual' diet. "A blood pressure reduction of the scale caused by a higher consumption of plant-based diets, even with limited animal products would result in a 14% reduction in strokes, a 9% reduction in heart attacks and a 7% reduction in overall mortality. "This is a significant finding as it highlights that complete eradication of animal products is not necessary to produce reductions and improvements in blood pressure. Essentially, any shift towards a plant-based diet is a good one." Senior author Professor Francesco Cappuccio of Warwick Medical School said: "The adoption of plant-based dietary patterns would also play a role in global food sustainability and security. They would contribute to a reduction in land use due to human activities, to global water conservation and to a significant reduction in global greenhouse gas emission. "The study shows the efficacy of a plant-based diet on blood pressure. However, the translation of this knowledge into real benefits to people, i.e. its effectiveness, depends on a variety of factors related to both individual choices and to governments' policy decisions. For example, for an individual, the ability to adopt a plant-based diet would be influenced by socio-economic factors (costs, availability, access), perceived benefits and difficulties, resistance to change, age, health status, low adherence due to palatability and acceptance. "To overcome these barriers, we ought to formulate strategies to influence beliefs about plant-based diets, plant food availability and costs, multisectoral actions to foster policy changes focusing on environmental sustainability of food production, science gathering and health consequences." Health and happiness depend on each other Georgetown University, July 22, 2020 Good health and a happy outlook on life may seem like equally worthy yet independent goals. A growing body of research, however, bolsters the case that a happy outlook can have a very real impact on your physical well-being. New research published in the journal Psychological Science shows that both online and in-person psychological interventions -- tactics specifically designed to boost subjective well-being -- have positive effects on self-reported physical health. The online and in-person interventions were equally effective. "Though prior studies have shown that happier people tend to have better cardiovascular health and immune-system responses than their less happy counterparts," said Kostadin Kushlev, a professor in Georgetown University's Department of Psychology and one of the authors of the paper, "our research is one of the first randomized controlled trials to suggest that increasing the psychological well-being even of generally healthy adults can have benefits to their physical health." Intervention for Healthy Outcomes Over the course of six months, Kushlev and his colleagues at the University of Virginia and the University of British Columbia examined how improving the subjective well-being of people who were not hospitalized or otherwise undergoing medical treatment affected their physical health. A group of 155 adults between the ages of 25 and 75 were randomly assigned either to a wait-list control condition or a 12-week positive psychological intervention that addressed three different sources of happiness: the "Core Self," the "Experiential Self," and the "Social Self." The first 3 weeks of the program focused on the Core Self, helping individuals identify their personal values, strengths, and goals. The next 5 weeks focused on the Experiential Self, covering emotion regulation and mindfulness. This phase also gave participants tools to identify maladaptive patterns of thinking. The final 4 weeks of the program addressed the Social Self, teaching techniques to cultivate gratitude, foster positive social interactions, and engage more with their community. The program, called Enduring Happiness and Continued Self-Enhancement (ENHANCE), consisted of weekly modules either led by a trained clinician or completed individually using a customized online platform. None of the modules focused on promoting physical health or health behaviors, such as sleep, exercise, or diet. Each module featured an hour-long lesson with information and exercises; a weekly writing assignment, such as journaling; and an active behavioral component, such as guided meditation. "All of the activities were evidence-based tools to increase subjective well-being," Kushlev noted. When the program concluded, the participants were given individual evaluations and recommendations of which modules would be most effective at improving their happiness in the long term. Three months after the conclusion of the trial, researchers followed up with the participants to evaluate their well-being and health. A Happy Future Participants who received the intervention reported increasing levels of subjective well-being over the course of the 12-week program. They also reported fewer sick days than control participants throughout the program and 3 months after it ended. The online mode of administering the program was shown to be as effective as the in-person mode led by trained facilitators. "These results speak to the potential of such interventions to be scaled in ways that reach more people in environments such as college campuses to help increase happiness and promote better mental health among students," Kushlev said. Rely on gut feeling? New research identifies how second brain in gut communicates Finders University (Australia), July 24, 2020 You're faced with a big decision so your second brain provides what's normally referred to as 'gut instinct', but how did this sensation reach you before it was too late? The Enteric Nervous System (ENS) is an extensive network of neurons and transmitters wrapped in and around the human gut with the prime function of managing digestion, but researchers at Flinders University are delving into the complexity of this brain like system to uncover it's secret capabilities. In a new study published in the eNeuro journal, Professor Nick Spencer's laboratory has identified a particular type of neuron in the gut wall that communicates signals to other neurons outside the gut, near the spinal cord and up to the brain. "There is significant interest in how the gut communicates with the brain as a major unresolved issue because of growing evidence that many diseases may first start in the gut and then travel to the brain, an example of which is Parkinson's Disease," says Professor Spencer. "The new study has uncovered how viscerofugal neurons provide a pathway so our gut can "sense" what is going on inside the gut wall, then relay this sensory information more dynamically than was previously assumed to other organs, like the spinal cord and brain which influence our decisions, mood and general wellbeing." The results reveal why the ENS might play an increasingly important part on human health, and could shed light on potential new treatments for conditions like Parkinson's disease. This study represents a big step towards understanding ENS functions and the complexity of the gut and brain connection through the neurons that allow communication in the body. Professor Spencer says there is increasing interest in understanding how the nervous system in the gut (ENS) communicates with the brain, to give us all those sensations we know of. "What is particularly exciting about the gut, is that it is unlike all other internal organs (e.g. heart, liver, bladder) because the gut has its own nervous system, which can function independently of the brain or spinal cord. Understanding how the gut communicates and controls other organs in the body can lead to important breakthroughs for disease treatment and this is an important step in the right direction." The role of functional foods in treating chronic diseases Wuhan Sports University (China), July 24, 2020 In this study, researchers at Wuhan Sports University in China summarized several widely investigated bioactive components used as functional foods and their role in autophagy. Their review was published in the journal Food Science and Human Wellness. Functional foods, which could be either natural or processed foods that contain bioactive compounds, can provide health-promoting effects beyond basic nutrition. These foods also offer the benefit of preventing or treating chronic diseases. The bioactive components in functional foods often have pleiotropic effects, such as antioxidant, anti-inflammatory, hypolipidemic (cholesterol-lowering), blood sugar-regulating, cytoprotective and neuroprotective functions. Autophagy is a highly conserved cellular process used by the body to eliminate aberrant components in eukaryotic cells. It also plays an essential role in promoting health and preventing or treating several chronic diseases. When cells are in a stressful condition, autophagy accelerates the clearance of damaged or toxic cellular protein aggregates or dysfunctional cell organelles to maintain homeostasis. In this review, the researchers focused on several bioactive components of functional foods, such as resveratrol, epigallocatechin-3-gallate, curcumin and trehalose, and their regulatory functions in autophagy. They believe this review could serve as a reference or provide novel ideas for the development of functional foods capable of modulating autophagy for the treatment of chronic diseases. Combination of vitamin E and Lactobacillius plantarum reverses mercuric chloride-induced neurotoxicity King Saud University, July 23, 2020 According to news originating from Riyadh, Saudi Arabia, by NewsRx editors, the research stated, “Mercury is the third most hazardous heavy metal and its toxicity causes a severe health risk through unfavorable detrimental pathological and biochemical effects. Mercury is widely found in many ecological and certain occupational settings.” Our news editors obtained a quote from the research from King Saud University: “The aim of this study is to elucidate the neuroprotective role of vitamin E (VE) and Lactobacillus plantarum (LTB) either alone or in combination against a toxic sublethal dose of Mercuric chloride (MC). First group served as a normal control group; rats from the second group were intoxicated with (5 mg/kg MC once daily); the third group was treated with VE; the fourth group was treated with LTB; and the fifth group was treated with VE and LTB. All treatments were given daily along with MC for fourteen days. The results of the current study confirmed that MC prompted an elevation in serum TNF-a, IL-6 and brain lipid peroxides, protein expression of mitogen-activated protein kinase (MAPK) and mRNA expression of Bax and caspase-3 level as well as DNA degradation. However, Brain-derived neurotrophic factor (BDNF) and cAMP response element-binding (CREB) protein expressions, GSH level and SOD activity were down-regulated. The intake of LTB and/or VE along with MC intoxication significantly mitigated the alteration in all the previous parameters. Moreover, histopathological analysis of brain sections confirmed that MC-induced brain injury and LTB or VE alone or together were capable of ameliorating brain artitechture.” According to the news editors, the research concluded: “The combination of LTB and VE was an effective therapy in the management of MC-induced neuroioxicity and this combination can be considered a useful therapeutic candidate against brain injury induced by MC. BDNF, MAPK and CREB protein expressions are implicated in MC -induced brain injury and its treatment.” Plant-based diets high in carbs improve type 1 diabetes, according to new case studies Physicians Committee for Responsible Medicine, July 24, 2020 Plant-based diets rich in whole carbohydrates can improve insulin sensitivity and other health markers in individuals with type 1 diabetes, according to two case studies published by researchers from the Physicians Committee for Responsible Medicine in the Journal of Diabetes & Metabolism. Both case studies followed individuals with type 1 diabetes who adopted plant-based diets rich in whole carbohydrates--including fruits, vegetables, whole grains, and legumes. The patients' health care teams tracked their blood sugar control, heart disease risk factors, and other health measurements before and after the diet change. One case study followed a female patient who was diagnosed with type 1 diabetes in 2018. At the time, her A1c was 8.7%. She initially adopted a low-carbohydrate (less than 30 grams of carbohydrate per day), high-fat diet that was high in meat and dairy. Her blood sugar stabilized, but she required more insulin per gram of carbohydrate consumed. Her total cholesterol also increased from 175 to 221 mg/dL. In January 2019, she switched to a plant-based diet, eliminating dairy products, eggs, and meat. The patient was able to decrease her insulin dosage, maintain her A1c level at 5.4%, and drop her cholesterol level to 158 mg/dL. "This study challenges the misconception that carbs are the enemy when it comes to diabetes," says study author Hana Kahleova, MD, PhD, director of clinical research at the Physicians Committee. "The patient in this case study experienced the opposite: Adding more healthful carbohydrates to her diet stabilized her glycemic control, reduced her insulin needs, and boosted her overall health." The other individual--a 42-year-old man who had been diagnosed with type 1 diabetes at age 25--eliminated animal products from his diet and switched to a whole food, plant-based diet. He increased his consumption of carbohydrates from 150 grams to 400-450 grams per day. After adopting a carbohydrate-rich plant-based diet, he lost weight, required less insulin, and reduced his A1c--a measure of blood sugar levels over a 3-month period--from 6.2% to a range between 5.5-5.8%. The authors note that a previous small study supported the case studies' results, finding that a high-carbohydrate, high-fiber diet improved glycemic control in 10 people with type 1 diabetes. As a next step, the authors suggest that randomized clinical trials are needed to verify the case studies' findings, assess their generalizability, and quantify the effectiveness of plant-based diets in the management of type 1 diabetes. Previous studies have found that low-fat, plant-based diets can be beneficial for those with type 2 diabetes. Research has also shown that those eating a plant-based diet have approximately half the risk of developing type 2 diabetes, compared with non-vegetarians. "Decades of research has proven that a plant-based diet can be beneficial for those with type 2 diabetes. Now, these groundbreaking case studies are offering hope that the same may be true for those with type 1 diabetes," adds Dr. Kahleova. Raised iron levels linked to reduced life expectancy Imperial College London, July 24, 2020 Having too much iron in the body puts your long term health at risk but it could also take years off your life. These are the findings of a study using large scale genetic data to assess the impacts across a population of having naturally raised levels of iron, in terms of years of life expectancy. According to the researchers, the findings—which help to cut through the noise caused by confounding factors such as age, sex or diet—add to the increasingly complex picture of iron's role in our health and highlight the risks of having raised levels of iron. Dr. Dipender Gill, from Imperial's School of Public Health and who supervised the study, said: "We have known for a long time that having too much or too little iron in your system can have serious impacts on your health, and that effectively modifying iron levels can help many people with underlying conditions. Our findings build on previous work to clarify that picture further, showing that people who have genetic predisposition to slightly raised levels of iron in the body have reduced life expectancy on average. While we did not look directly at the impact of taking supplements, our results suggest that there is a need to better understand the health implications of people boosting their iron levels with supplements when they don't need to." Double-edged sword Iron is used by the body to make red blood cells, which carry oxygen. Most people without underlying health conditions should be able to get enough iron from their diet. But disrupting the balance can lead to a host of health implications: too little iron is associated with fatigue and impaired immune system, while too much can cause liver failure, and in high enough doses can even be fatal. A number of studies suggest small changes in iron levels can have protective and detrimental effects for different diseases, such as heart disease, stroke and infections. But the net effect of varying iron levels on life expectancy remains unclear. In the latest study, published this month in the journal Clinical Nutrition, Dr. Gill and Mr. Iyas Daghlas from Harvard Medical School used a statistical technique called Mendelian randomization to try to explore the effect of increasing levels of iron on health—using people's genetic variation as an indicator of their iron levels. The researchers trawled genetic data from almost 49,000 people to find genetic variants linked to iron levels. They focused on three points in the genome where a single "letter" difference in the DNA—called a single nucleotide polymorphism (SNP)—can slightly increase or reduce a person's iron level. When these same SNPs were then screened in a larger dataset combing lifespan data for more than one million people, they found that the genetic markers for higher iron levels on average associated with reduced life expectancy. The analysis revealed that for every one point of standard deviation increase in genetically predicted serum iron above baseline, people had an estimated 0.7 fewer years of lifespan. Furthermore, the findings were unlikely to be biased by lifestyle factors. A body of work The work builds on a number of previous studies by Dr. Gill, which have used genetic data to investigate the role of iron in hundreds of diseases. A 2017 study revealed the link between high iron levels and lower risk of heart disease. Further studies from 2019 showed naturally higher iron levels were associated with a lower risk of high cholesterol levels, reducing the risk of arteries becoming furred with a build-up of fatty substances, but also carried with it a higher risk of blood clots and skin infections. Taken together, the studies build a complex picture of iron status in health. The authors stress that the genetic markers themselves do not indicate reduced life expectancy or risk in the wider context, but are a tool to study how iron levels relate to health without the influence of a number of complex confounding factors such as diet, economic background, or smoking status. They add that the findings should not currently be applied clinically, at the individual level. Dr. Gill explained: "It's important to put these findings in context. Our analysis is indirect and uses genetic data as a proxy for raised iron levels. But the clinical implications warrant further investigation and could be important for long-term health at the population level." Mr Iyas Daghlas, from Harvard Medical School, said: "These findings should not yet be extrapolated to clinical practice, but they further support the idea that people without an iron deficiency are unlikely to benefit from supplementation, and that it may actually do them harm. We emphasize that these results should not be applied to patient populations with a compelling reason for iron supplementation, such as patients with symptomatic iron deficiency anemia, or in patients with heart failure." Seven reasons to eat more watermelon Life Extension, July 22, 2020 There's a reason why summer is the season for watermelon. Not only does this favorite fruit reach its peak flavors during the warmer months, watermelon is also even more nutrient-rich this time of year. From being a great source of raw lycopene to its hydrating nature, here are seven reasons to eat more watermelon. Lycopene is the pigment that gives red and pink fruits, such as tomatoes, watermelons and pink grapefruit, their characteristic color. Lycopene has been linked to health benefits ranging from heart health to protection against sunburns and certain types of cancers. 1. Watermelon is a top source of lycopene. Tomatoes get the glory when it comes to lycopene, but watermelon actually has more ? about 40 percent more, on average. Our bodies also absorb lycopene from watermelon more easily. Unlike tomatoes, which need to be cooked in order to maximize lycopene absorption, we can effectively absorb and reap the benefits of lycopene from raw watermelon. 2. It's hydrating.No surprise here. (It is called watermelon, after all!) But you may find it interesting that watermelon is 92 percent water, so by enjoying it, you really are eating your way toward better hydration. 3. It may improve blood pressure; is a top source of citrulline, which can help to improve blood flow and blood pressure 4. Because it's so sweet, watermelon has a reputation for being high in sugar, but most fruits arenaturally high in sugar, but they're also rich in nutrients. However, compared to sweet potatoes, watermelon has only one-fourth of the carbs and only half the sugar. 5. All of the goodness of watermelon (lycopene, beta carotene, vitamin C, vitamin A, fiber and overall antioxidants) gets better with age. The redder the fruit's flesh, the higher the nutrient concentration. 6. Most of us eat the red flesh and leave the rinds, but the rinds are entirely edible (just remove the outer peel), and are as nutritious as the flesh itself. The rinds can be sliced and added to your favorite stir-fry recipe, juiced or pureed for chilled soups. 7. It can be prepared in countless creative ways.Simply slice it and eat it plain, or with a sprinkle of salt. Or go with the classic pairing of watermelon: fresh mint and feta (or goat cheese, for a lower-sodium option). Make watermelon salsa, using watermelon in place of some (or all) of the tomatoes in your favorite salsa recipe. Grill it. Juice it. Puree it, rind and all, for soups and mocktails. The options are endless! Molly Kimball, RD, CSSD, registered dietitian with Ochsner Health System, manages the nutrition department of Ochsner Fitness Center and is founder of the Ochsner Eat Fit nonprofit restaurant initiative.