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In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusses the growing epidemic of sarcopenia, the loss of muscle mass and strength, accelerated by the use of GLP-1 medications. She emphasizes the importance of muscle health for overall longevity and introduces the concept of "muscle span."Gil and Gabrielle explore the critical role of skeletal muscle as a metabolically active organ, its impact on longevity, and the best ways to build and maintain muscle throughout life. They delve into the public's misconception of prioritizing today's needs over tomorrow's health, highlighting the need for preventative measures like strength training. The conversation touches upon the complexities of protein consumption, emphasizing the importance of meeting daily protein goals and the often-overlooked nutritional needs for healthy aging.Finally, they address common misconceptions regarding hormone replacement therapy and the importance of prioritizing muscle-centric medicine. This episode offers actionable insights and valuable knowledge for anyone seeking to optimize their health and longevity through a deeper understanding of muscle health.Guest-at-a-Glance
Chapters 00:00 Introduction to Circadian Rhythms and Skeletal Muscle 02:52 Understanding the Circadian Clock 06:12 Dysregulation of Circadian Rhythms 09:06 Impact of Inflammation on Circadian Clocks 12:00 Peripheral Clocks and Their Independence 15:06 Exercise Timing and Performance 18:06 Feeding Patterns and Circadian Rhythms 21:00 Chronotypes and Individual Differences 23:59 Caffeine and Its Effects on the Clock 27:02 Adaptation of Circadian Clocks in Extreme Conditions 29:58 Alcohol's Impact on Circadian Function 31:01 The Impact of Circadian Clocks on Muscle and Tendon Health 36:34 Aging and Its Effects on Circadian Rhythms 40:47 Injury and Circadian Clocks: Understanding the Connection 43:10 The Role of Nutrition and Feeding Patterns 48:29 Circadian Disruption and Metabolic Health 51:50 Practical Applications for Maintaining Healthy Clocks Takeaways Circadian clocks are molecular timers found in every cell. The clock regulates metabolism and gene expression based on time of day. Dysregulation can lead to health issues like increased glucose levels. Peripheral clocks can operate independently of the central clock. Exercise timing can enhance performance and adaptation. Feeding patterns should align with activity for optimal health. Chronotype influences individual preferences for sleep and activity. Caffeine affects the sympathetic nervous system but doesn't phase shift the clock. Alcohol can disrupt circadian function and health. Adaptation of clocks can occur even in extreme light conditions. Circadian clocks significantly influence muscle and tendon health. Disruption of circadian rhythms can lead to metabolic issues. Aging affects the ability of circadian clocks to regulate gene expression. Inactivity does not stop circadian clocks, but it affects their function. Nutrition timing is crucial for maintaining healthy circadian rhythms. Exercise can enhance the function of circadian clocks in muscles. Understanding the communication between muscle and tendon is vital for rehabilitation. Time-restricted feeding may extend lifespan and improve health. Research on circadian rhythms can inform strategies for injury recovery. Maintaining a consistent activity and feeding schedule supports clock health. Karyn's profile: https://physiology.med.ufl.edu/profile/esser-karyn/ Karyn's Linkedin: https://www.linkedin.com/in/karyn-esser-a187333 Notes: https://jackedathlete.com/podcast-129-circadian-rhythms-with-karyn-esser/
BUFFALO, NY- January 22, 2025 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) on December 12, 2024, Volume 16, Issue 22, titled “Arginase-II gene deficiency reduces skeletal muscle aging in mice.” Researchers Matteo Caretti, Duilio Michele Potenza, Guillaume Ajalbert, Urs Albrecht, Xiu-Fen Ming, Andrea Brenna, and Zhihong Yang from the University of Fribourg found that removing a specific gene, called arginase-II (Arg-II), can slow down muscle aging in mice. Their research showed that older mice lacking this gene stayed more active and had healthier skeletal muscles compared to normal aging mice. This discovery could lead to new treatments to help people maintain muscle strength and mobility as they become older. As people age, their muscles naturally get weaker, leading to reduced physical activity and overall quality of life. This condition, known as sarcopenia, occurs because of muscle fiber loss, inflammation, and scar tissue buildup. The study found that the Arg-II gene contributes to this process. The research team compared normal mice with mice lacking the Arg-II gene and discovered that in general, the mice without the gene had improved muscle health, reduced inflammation, and fewer signs of age-related muscle decline. It was also found that older male mice deficient in the Arg-II gene were more active, particularly during their peak nighttime activity. These mice had stronger muscles and performed better in physical tests. Interestingly, the benefits of Arg-II gene removal were more pronounced in male mice compared to females, suggesting that hormonal or genetic differences might play a role in age-related muscle loss. “The improved phenotype of arg-ii-/- mice in aging is associated with reduced sarcopenia, cellular senescence, inflammation, and fibrosis, whereas age-associated decline of microvascular endothelial cell density, satellite cell numbers, and muscle fiber types in skeletal muscle is prevented in arg-ii-/- mice.” ARG-II protein was not found in muscle fibers but instead in surrounding cells such as fibroblasts and blood vessel cells, which makes scientists believe this gene influences muscle aging indirectly. Independently of that, the findings suggest that targeting the Arg-II gene could help slow down age-related muscle deterioration and improve muscle function in older adults. "[...] we demonstrate an increased arg-ii gene expression level in aging skeletal muscle and found Arg-II protein expression in endothelial cells and fibroblasts, but not in skeletal muscle fibers, macrophages, and satellite cells." While these results are promising, further research is needed to determine whether blocking the Arg-II gene in humans could provide similar benefits. Furthermore, understanding why male and female mice responded differently to the gene removal will be essential before personalized treatments for age-related muscle loss. If future studies confirm these findings in humans, targeting Arg-II could become a valuable strategy to help adults maintain muscle strength, mobility, and overall quality of life as they age. DOI - https://doi.org/10.18632/aging.206173 Corresponding authors - Andrea Brenna - andrea.brenna@unifr.ch, and Zhihong Yang - zhihong.yang@unifr.ch Video short - https://www.youtube.com/watch?v=uDxSCO2Y7-w About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com. MEDIA@IMPACTJOURNALS.COM
As we wrap up another incredible year of Live Well, Be Well, I'm excited to share with you my personal top takeaways from the fascinating conversations that have shaped 2024. In this special solo episode, I reflect on the transformative insights gained from speaking with some of the brightest minds in health, wellbeing, and personal development.I explore how our understanding of stress, longevity, friendship, decision-making, and compassion has evolved through these meaningful conversations. What makes this episode particularly special is how it demonstrates that true wellbeing isn't just about physical health – it's a multifaceted journey that encompasses our mental, emotional, and social wellbeing too.Thank you for listening! Let me know your thoughts on this episode, and don't forget to share it with anyone who might find it helpful.Sarah Ann***Thank you to my wonderful sponsors! EXHALE COFFEE | Ridiculously healthy coffee works well for me. https://exhalecoffee.com/pages/sarahUse code FREETRIALSARAH for your free trial.Squarespace | A website makes it real. http://squarespace.com/LiveWell Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. ***If you enjoyed this episode you might also like:The #1 BETTER HEALTH Technique You Never Knew Existed! Dr Kristin Neffhttps://www.youtube.com/watch?v=jKq069w4rjISimon Sinek: The 8-Minute Rule That Could SAVE YOUR Friendshipshttps://www.youtube.com/watch?v=3JCjOQv9Y5EDr. Chris Van Tulleken: How Ultra-Processed Foods Are Making Us Sickhttps://www.youtube.com/watch?v=6SxK9MFmH4c***Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter
Dive into an extraordinary conversation with Dr. Gabrielle Lyon and Dr. Jamie Baum, Associate Professor and Director of the Center for Human Nutrition at the University of Arkansas. In this episode, we explore revolutionary topics:The role of skeletal muscle in appetite regulation.Cutting-edge research on perimenopause and postmenopause nutrition.How dietary protein impacts health and weight management.Surprising findings on protein supplementation and sleep quality.The science behind muscle-brain crosstalk and its effects on aging.Dr. Baum shares her journey into research focused on women's health, the underrepresentation of women in protein science, and why muscle health is key to longevity. Learn about the latest studies on protein types (whey, casein, soy), appetite signals, and why muscle may be the organ of the future.
What is sarcopenia and is it life-threatening? Edwin Davila, DO, MS, CISSN, ACSM-CEP, from WellMed at SW Military in San Antonio, Texas explains the importance of maintaining skeletal muscle mass in older adults. Tune in to this Docs in Pod with Ron Aaron and Desarea Murray, NP from WellMed at Live Oak. Listen to the podcast by searching for “Docs in a Pod” on Apple Podcasts, Google Podcasts, Pandora, Podbean and Stitcher. Docs in a Pod focuses on health issues affecting adults. Clinicians and other health partners discuss stories, topics and tips to help you live healthier. Docs in a Pod airs on Saturdays in the following cities: 7:00 to 7:30 am CT: San Antonio (930 AM The Answer) DFW (660 AM, 92.9 FM [Dallas], 95.5 FM [Arlington], 99.9 FM [Fort Worth]) 6:30 to 7:00 pm CT: Houston (1070 AM/103.3 FM The Answer) 7:00 to 7:30 pm CT: Austin (KLBJ 590 AM/99.7 FM) Docs in a Pod also airs on Sundays in the following cities: 1:00-1:30 pm ET: Tampa (860 AM/93.7FM)
Guerra, DJ. 2024. lecture notes Leach, Donovan. 1967 "Mountain Jam" Allman Brothers https://youtu.be/w9ZubobGMLs?si=uHLon1CvCiCSiqtX --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Welcome to the (delayed) 10th & SUMMER BOTOX SPECIAL EPISODE of BSCOS Paediatric Orthopaedic Digest (POD)cast with Caroline Edwards, Head of Childrens Surgery at Plymouth hospital who started her consultant career at Southampton Childrens Hospital, she set up and developed the neuromuscular service. She proposes a "hub and spoke" model for learning at busy tertiary centres and shared her research on the surgical vulnerability score, a tool to assess the likelihood of early death in patients with neuromuscular disorders. Caroline highlights the challenges faced by young adults transitioning from clinic care for cerebral palsy and suggested district general hospitals could provide dedicated clinics. Listen in to the episode to learn more! We scoured 35 journals & highlighted the most impactful studies that we feel can change practice or improve outcomes in Paediatric Orthopaedics. Follow Updates on @BSCOS_UK REFERENCES: 1. Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril. Howard JJ & Herzog W. Front Neurol. Feb 2021. PMID: 33679586 2. Virtual Reality Distraction Is No Better Than Simple Distraction Techniques for Reducing Pain and Anxiety During Pediatric Orthopaedic Outpatient Procedures: A Randomized Controlled Trial. Fabricant PD et al. Clin Orthop Relat Res. May 2024. PMID: 37939199 3. Effect of parental touch on relieving acute procedural pain in neonates and parental anxiety (Petal): a multicentre, randomised controlled trial in the UK. Hauck AGV et al. Lancet Child Adolesc Health. April 2024. PMID: 38373429. 4. REM Sleep Preserves Affective Response to Social Stress-Experimental Study. Halonen et al. eNeuro. June 2024. PMID: 38802242 5. Functional electrical stimulation during walking in children with unilateral spastic cerebral palsy: A randomized cross-over trial. Moll et al. Dev Med Child Neurol. May 2024. PMID: 37823431. 6. Clinical Effectiveness of Newborn Screening for Spinal Muscular Atrophy: A Nonrandomized Controlled Trial. Schwartz et al. JAMA Pediatr. June 2024. PMID: 38587854 7. Surgical management of proximal femoral unicameral bone cyst in children. Maximen et al + SOFOP. Bone Joint J. May 2024. PMID: 38688504 8. Treatment of Hip Displacement in Children With Cerebral Palsy: A 5-year Comparison of Proximal Femoral Osteotomy and Combined Femoral-Pelvic Osteotomy in 163 Children. Kiapekos N et al. J Pediatr Orthop. July 2024. PMID: 38477355 9. Impact of Pavlik Harness treatment on motor skills acquisition: A case-control study. Jesus AR et al. J Child Orthop. March 2024. PMID: 39100978 10. Deep Learning Analysis of Surgical Video Recordings to Assess Nontechnical Skills. Harari RE et al. JAMA Netw Open. July 2024. PMID: 39083274 11. Single versus double retrograde intramedullary nail technique for treatment of displaced proximal humeral fractures in children: A retrospective cohort study. Samara E et al. J Child Orthop. March 2024. PMID: 38831859 12. Can the Achilles tendon regenerate completely following percutaneous tenotomy in older children with clubfoot? Aroojis A et al. Int Orthop. June 2024. PMID: 38340143. 13. Guided Growth With Minifragment Plates for Angular Deformities in the Distal Radius in Skeletally Immature Patients. Preliminary Results. Soler-Jimenez A et al. J Pediatr Orthop. September 2024. PMID: 38767293. 14. Robot-assisted Temporary Hemiepiphysiodesis With Eight-plates for Lower Extremity Deformities in Children. Liang M et al. J Pediatr Orthop. April 2024. PMID: 38312109 Follow Hosts: @AnishPSangh @AlpsKothari @Pranai_B See as many of you as possible at the BSCOS sessions at the BOA in Birmingham!
In this episode, we're diving deep into the science of building muscle and speeding up those gains! If you're tired of feeling like progress is at a snail's pace, I've got three proven strategies that will help you see results faster. First up, we're talking nutrition and the critical role of protein in muscle synthesis. Discover how optimal protein intake, especially the right amount of leucine, can trigger muscle growth. Plus, I've got a free 7-day protein challenge waiting for you at jjvirgin.com/7day to kickstart your journey. Next, we'll explore the power of pre-workout carbs and their surprising benefits. A 2016 study revealed that carbs before exercise can boost performance, reduce fatigue, and even enhance brain function during workouts. I'll share my personal experiments with fasted versus non-fasted workouts and why timing your carbs and protein around your exercise sessions is crucial for maximizing muscle gains. Supplements can make a significant difference, and I'll highlight the heavy hitters like creatine, vitamin D, and fish oil. Learn which supplemennt can supercharge your energy during high-intensity workouts, why vitamin D is essential for muscle function, and the muscle-building benefits of omega-3s from fish oil. Plus, I'll introduce you to a supplement that enhances mitochondrial health for better endurance and recovery. Finally, we'll touch on the importance of hormones like thyroid and estrogen in muscle building. Balancing these hormones can significantly impact your strength and muscle growth. I'll also share practical tips for incorporating recovery techniques such as sauna sessions, red light therapy, and massages into your routine to optimize muscle repair and growth. Don't miss out on these game-changing tips! FULL show notes: https://www.jjvirgin.com/buildmuscle2024 Use my Eat Protein First Calculator: http://jjvirgin.com/proteinfirst Epsom Salt: https://amzn.to/3IxgmMm Vital Choice wild-caught seafood: https://vitalchoice.sjv.io/daKYGy Foam Roller: https://amzn.to/3PlAGE3 Kooru Cold Plunge: https://www.koorucoldplunges.com/ and use code JJVIP500 for $500 off. Timeline Mitopure (Urolithin A): https://www.timelinenutrition.com/partners/jj-virgin Sunlighten Sauna: https://get.sunlighten.com/JJVirgin use promo code JJVIRGIN when requesting pricing information for $600 off. Download my FREE Best Rest Sleep Cheat Sheet: https://jjvirgin.com/sleep Therasage saunas & red light therapy: https://therasage.com/discount/VIRGIN20?rfsn=7719794.ae138d&utm_source=refersion&utm_medium=affiliate&utm_campaign=7719794.ae138d use code VIRGIN20 for 20% off Study: Effect of Carbohydrate Intake on Maximal Power Output and Cognitive Performances: https://consensus.app/papers/carbohydrate-intake-maximal-power-output-cognitive-pomportes/687ae139a6255636ab549f00de5ed80b/?utm_source=chatgpt Study: Creatine Supplementation and Skeletal Muscle Metabolism for Building Muscle Mass- Review of the Potential Mechanisms of Action: https://consensus.app/papers/creatine-supplementation-skeletal-muscle-metabolism-farshidfar/818dd4ef9aa85e1c98179306d1259491/?utm_source=chatgpt Study: Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women: https://consensus.app/papers/changes-proinflammatory-markers-leucine-concentrations-gmiat/498e3f96124d5e3183e554e3042209df/?utm_source=chatgpt Study: Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge: https://consensus.app/papers/increases-muscle-mass-modulates-aktfoxo-tlr4-signaling-liu/b643eda9cd955f3a896224cda5a710a2/?utm_source=chatgpt Study: Role of thyroid hormone in skeletal muscle physiology: https://consensus.app/papers/role-thyroid-hormone-muscle-physiology-bloise/7e60a07344355ccb920ad732999b043a/?utm_source=chatgpt Study: The Influence of Estrogen on Skeletal Muscle: https://consensus.app/papers/influence-estrogen-skeletal-muscle-enns/a09639083d7b5a0c8342fb88cb735309/?utm_source=chatgpt Study: Impact of Cortisol on Reduction in Muscle Strength and Mass: A Mendelian Randomization Study: https://consensus.app/papers/impact-cortisol-reduction-muscle-strength-mass-mendelian-katsuhara/90d796b0f5a055218acfb81b6d1dc716/?utm_source=chatgpt Study: A post-exercise infrared sauna session improves recovery of neuromuscular performance and muscle soreness after resistance exercise training: https://consensus.app/papers/postexercise-infrared-session-improves-recovery-ahokas/c114553985dd5522a0ee8994d2a0ec48/?utm_source=chatgpt Study: Low-level laser (light) therapy increases mitochondrial membrane potential and ATP synthesis in C2C12 myotubes with a peak response at 3-6 hours: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355185/ Study: Enhanced skeletal muscle regrowth and remodeling in massaged and contralateral non‐massaged hindlimb: https://consensus.app/papers/enhanced-muscle-regrowth-remodelling-massaged-hindlimb-miller/2336402483345dcf984c34764d57ddb0/?utm_source=chatgpt Episode Sponsors: Try Timeline: https://www.timelinenutrition.com/shop?rfsn=7082975.4b75243 Use code JJ10 for 10% off all products Go to qualialife.com/VIRGINWELLNESS to try Qualia risk free for up to 100 days and code VIRGINWELLNESS for an additional 15% off
Everything in moderation, right? Maybe you exercise regularly and watch what you eat but you also enjoy the occasional glass of wine. Maybe you want to enjoy alcohol a few times a week, in moderation. Is it possible to enjoy a drink and still hit your physical goals? Is all alcohol toxic? Are some alcohols less toxic than others? Does alcohol consumption truly cause cancer? What is the impact of alcohol on our brain, muscles, gut healthy and cellular health? In this episode Chalene Johnson breaks down the latest research on alcohol consumption and its impact on overall health. She talks about the pros and cons of moderate drinking, and shares her own experience with alcohol. This episode will help listeners take a closer look at their relationship with alcohol. With insights from recent research, this episode is a must listen if you're considering if you need to cut back or quit completely. Listen to better understand how alcohol impacts muscle growth, hormones, brain health, and cancer risk. Chalene also opens up about her journey of rethinking her drinking habits and the possibility of creating a supportive 30-day Alcohol free challenge. Watch on YouTube this Sunday!! Join Chalene on Patreon http://chalene.com/more for all the things that can't go on the regular podcast PLUS listen to the Rachel and Dave Hollis Series! Join the all-new Phase It!! A Personalized Plan to Fit Your Life
In this episode, Codie Sanchez and her guests discuss the connection between obesity, diabetes, and skeletal muscle problems, emphasizing fitness as a daily habit. Codie's husband and former Navy Seal, Chris Petkas, shares practical fitness tips, including kettlebell workouts and incorporating healthy habits into your relationship. Then, Dr. Gabrielle Lyon talks about the importance of protein, muscle mass, and the differences between plant-based and animal-based proteins. They also cover modern health trends and offer advice for improving fitness and wellness. The episode aims to provide insights into achieving freedom and richness through health and fitness. 00:00 Introduction: Questioning the Obesity Epidemic 02:14 Steal My Rich Friend: Chris Petkas 03:12 Kettlebell Workouts: The Ultimate Fitness Tool 05:28 Habits vs. Hygiene in Fitness 14:46 Sunday Recovery Routine 18:10 Nutrition and Eating Habits 30:30 Chronic Pain Solutions 33:57 Integrating Health into Relationships 37:52 Steal My Rich Friend: Gabrielle Lyon 42:07 Marketing Taglines and USDA Control 42:42 Processed Foods vs. Whole Foods 47:42 Practical Tips for Protein Intake 51:47 The Role of Skeletal Muscle in Longevity 01:02:08 Navigating Fitness and Parenthood 01:14:16 Ozempic and the Pharmaceutical Industry
I sit down with Dr. Mike Israetel, founder of RP Strength, to discuss the crucial role of skeletal muscle in health and longevity. We delve into the science behind muscle hypertrophy, strength maintenance, and why building muscle is essential as we age. Dr. Israetel shares evidence-based tips on effective strength training, the benefits of muscle mass for metabolic health, and how to overcome common misconceptions about strength training, especially for women. Tune in to learn how to maximize your muscle growth and improve your overall health, no matter your age!
In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems. She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex. She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon's practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com. Andrew's New Book Protocols: An Operating Manual for the Human Body: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Levels: https://levels.link/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Timestamps 00:00:00 Protocols Book; Dr. Gabrielle Lyon 00:03:23 Sponsors: Maui Nui, Levels & Helix Sleep 00:07:40 Skeletal Muscle & Longevity 00:11:25 “Under-muscled”, Leucine & Muscle Health 00:15:55 Muscle Health 00:19:45 Tool: Carbohydrate Consumption & Activity, Glycogen 00:25:14 Tools: Nutrition for Healthy Skeletal Muscle, First Meal 00:31:57 Sponsor: AG1 00:33:46 Quality Protein, Animal & Plant-Based Proteins 00:37:36 Dietary Protein Recommendations, Meal Threshold 00:41:19 Muscle Health & Aging 00:46:02 Supplements & Creatine; Dietary Protein 00:50:07 Tool: Dietary Protein Recommendation; Gout & Cancer Risk 00:52:43 Effects of Dietary Protein & Exercise on Body Composition 01:03:06 Thermic Effects, Protein 01:05:02 Sponsor: InsideTracker 01:06:14 Protein & Satiety, Insulin & Glucose 01:12:04 Tool: Older Adults, Resistance Training & Dietary Protein 01:17:48 Dietary Protein, mTOR & Cancer Risk 01:21:36 Muscle Span & Aging, Sedentary Behaviors 01:24:00 Mixed Meals, Protein Quality, Fiber 01:29:21 Inactivity & Insulin Resistance, Inflammation 01:38:43 Exercise & Myokines, Brain Health & BDNF 01:44:11 Tool: Resistance Training Protocols, Hypertrophy, “High Ground” 01:52:51 High Ground Exercises; Tendon Strength; Training Duration, Blue Zones 01:58:19 Movement, Exercise & Older Adults 02:04:25 Tool: Protein Timing & Resistance Training; VO2 Max, Aging, Blood Work 02:11:13 Supplements: Creatine, Urolithin A, Whey Protein, Fish Oil, Collagen 02:20:18 Fasting, Older Adults; Tool: Meal Timing 02:25:18 Animal Proteins & Dairy; Organ Meats, Vegan; Magnesium, Zinc 02:30:59 Medications & Muscle Health 02:32:49 Obesity & GLP-1 Analogs, Ozempic, Mounjaro, Skeletal Muscle 02:40:48 Benefits of Skeletal Muscle & Aging 02:42:16 Tools: Nutrition & Resistance Training for Muscle Health 02:45:44 Mindset Tools: Standards vs. Goals; Vulnerability Points 02:52:00 Mindset Tools: Neutrality; Health & Worth 03:01:14 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter, Protocols Book Disclaimer
I'm honored to share the first episode of the new podcast, Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 1 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:07 Heart 00:03:55 Sponsors: Vitality Blueprint & Rhone 00:07:27 Muscle Types 00:09:54 VO2 max, Health & Mortality 00:15:49 Overall Health, Cardiorespiratory Fitness & All-Cause Mortality 00:25:23 Sponsor: AG1 00:26:54 Disease, Health & Mortality 00:30:02 Cardiac Muscle & Heart 00:38:29 Cardiac Muscle vs. Skeletal Muscle, Cardiac Advantages 00:43:53 Pacemakers & Heart Rate, Vagus Nerve 00:50:35 Why Doesn't the Heart Get Sore? 00:54:32 Heart & Exercise, Stroke Volume, Ejection Fraction, Cardiac Output 00:59:21 Heart Rate Variability 01:02:41 Sponsors: Momentous & LMNT 01:06:54 Why Do You Breathe?: Oxygen, Carbon Dioxide & Respiratory Rate 01:13:37 Respiratory Rate & Stress 01:15:08 Tool: The “Three I's”, Investigate: Heart Rate, Respiratory Rate, VO2 Max 01:19:53 Tool: Interpretation, Resting Heart Rate & Ranges 01:23:16 Tool: Interpretation: VO2 Max & Ranges 01:30:45 Athletes & Highest VO2 Max Scores 01:35:53 Elite Athletes & Context for VO2 Max Scores 01:41:42 Tool: Intervention, VO2 Max, Varying Exercise Intensities, SAID Principle 01:48:20 Tool: Varying Exercise Intensity; Intervals & Continuous Training; Frequency 01:58:18 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:59:55 Conclusion from Dr. Andrew Huberman Disclaimer
In this episode, I discuss the critical importance of building a strong heart and how to do it. I explain why the human body needs to breathe, the importance of cardiorespiratory fitness for sleep and exercise recovery, and its long-term implications for physical health, disease risk, and mortality. I explain how the heart functions, what determines heart rate, why the heart never gets sore, and the unique advantages of cardiac muscle over other muscle types. I explain how to use the ‘Three I's' (investigate, interpret, intervene) to assess and improve your cardiovascular fitness. I explain what VO2 max is (and other related metrics, e.g., heart rate variability), describe ranges based on age and elite performance, and discuss exercise regimens to improve VO2 max. Listeners of this episode will understand why cardiovascular health is vital for performance and overall health and learn a series of actionable tools to improve their cardiovascular fitness. Access the full show notes for this episode, including referenced articles and additional resources, at performpodcast.com. Thank you to our sponsors AG1: https://drinkag1.com/perform Vitality Blueprint: https://vitalityblueprint.com/perform Rhone: https://rhone.com/perform Momentous: https://www.livemomentous.com/perform LMNT: https://drinklmnt.com/perform Timestamps 00:00:00 Heart 00:02:48 Sponsors: Vitality Blueprint & Rhone 00:06:20 Muscle Types 00:08:47 VO2 max, Health & Mortality 00:14:42 Overall Health, Cardiorespiratory Fitness & All-Cause Mortality 00:24:16 Sponsor: AG1 00:25:47 Disease, Health & Mortality 00:28:55 Cardiac Muscle & Heart 00:37:22 Cardiac Muscle vs. Skeletal Muscle, Cardiac Advantages 00:42:46 Pacemakers & Heart Rate, Vagus Nerve 00:49:28 Why Doesn't the Heart Get Sore? 00:53:25 Heart & Exercise, Stroke Volume, Ejection Fraction, Cardiac Output 00:58:14 Heart Rate Variability 01:01:34 Sponsors: Momentous & LMNT 01:05:47 Why Do You Breathe?: Oxygen, Carbon Dioxide & Respiratory Rate 01:12:30 Respiratory Rate & Stress 01:14:01 Tool: The “Three I's”, Investigate: Heart Rate, Respiratory Rate, VO2 Max 01:18:46 Tool: Interpretation, Resting Heart Rate & Ranges 01:22:09 Tool: Interpretation: VO2 Max & Ranges 01:29:38 Athletes & Highest VO2 Max Scores 01:34:46 Elite Athletes & Context for VO2 Max Scores 01:40:35 Tool: Intervention, VO2 Max, Varying Exercise Intensities, SAID Principle 01:47:13 Tool: Varying Exercise Intensity; Intervals & Continuous Training; Frequency 01:57:41 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media Disclaimer & Disclosures
Join me, Dr Mike T Nelson, on the Flex Diet Podcast as Kristi Storzchuk, a PhD candidate in muscle physiology at Queens University, and I discuss her research on high-intensity interval training, mitochondria, glucose, lactate, and metabolic flexibility. This episode provides an in-depth look at the latest insights and findings from her work, offering a comprehensive understanding of metabolic flexibility and its implications for nutrition and recovery.Sponsors:Flex Diet Certification to open June 17, 2024: https://flexdiet.com/Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%Episode Chapters:(0:00:00) - Deep Dive Into Metabolic Flexibility(0:14:08) - Fasting and Metabolic Pathways in Humans(0:27:16) - Fasted Exercise and Metabolic Adaptation(0:42:24) - Defining Mitochondrial Biogenesis and Function(0:47:16) - Mitochondria, Fat Oxidation, and Exercise Physiology(0:55:20) - Carbs Impact on Lactate Threshold(1:04:29) - Metabolic Flexibility and Research ChallengesFlex Diet Podcast Episodes You May Enjoy:Episode 232: Beyond the Fitness Hype - The Real Significance of Autophagy for Fitness and Longevity with Dr. Kurt Escobar: https://miketnelson.com/episode-232-beyond-the-hype-the-real-significance-of-autophagy-with-dr-kurt-escobar/Episode 176: Metabolic Flexibility, Goal-Setting, and Violent Consistency with Adam Glass: https://miketnelson.com/metabolic-flexibility-goal-setting-and-violent-consistency-with-adam-glass/Connect with Kristi:Kristi's Instagram: https://www.instagram.com/krististoroschuk/Kristi's Website: https://krististoroschuk.com/Get In Touch:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/
Episode Highlights With Dr. Gabrielle LyonWhy she went back to study nutrition after becoming a doctor and what she learnedThe one patient that changed her life and her career trajectory Why we've been trying and failing to fix an obesity epidemic for 50 years and why we've gotten worse, not betterFat is just a symptom of unhealthy skeletal muscle What happens when a person doesn't have healthy skeletal muscleThe myth of “healthy sedentary individuals”Having healthy skeletal muscle is the only way to be healthySkeletal muscle is its own organ system and why this is important Why muscle is the best protection for having a healthy pregnancySkeletal muscle is the only organ systemWhat a DEXA is and what it measuresThe division between muscle mass and strengthWhat is happening in the body and the blood with unhealthy skeletal muscleThe loss of lean muscle mass is more detrimental than excess body fat!How waist-to-hip ratio is helpful in understanding where fat is Resources We MentionForever Strong: A New, Science-Based Strategy for Aging Well by Dr. Gabrielle LyonDr. Gabrielle Lyon - websiteDr. Gabrielle Lyon - Podcast
In this episode of Run with Fitpage, we have the leading Exercise and Nutrition researcher across the world - Dr. John Hawley. Professor Hawley discusses about carbohydrates for training and racing with out host, Vikas Singh. Dr. John Hawley, a distinguished academic with a plethora of accolades, serves as the Director of the Mary MacKillop Institute for Health Research and leads the Exercise and Nutrition Research Program. With a profound expertise in the interplay between exercise and diet, Dr. Hawley's research delves into the intricate mechanisms governing fat and carbohydrate metabolism, particularly in skeletal muscle. His pioneering work elucidates the molecular underpinnings of exercise training adaptation and the cellular pathways driving enhancements in insulin sensitivity. Dr. Hawley's scholarly contributions extend far and wide, with over 320 scientific publications and more than 100 articles in esteemed technical journals. He is a sought-after speaker at national and international scientific gatherings, captivating audiences with his insights into sports medicine and exercise biochemistry. Renowned for his expertise, Dr. Hawley serves as an Associate Editor for Sports Medicine and holds positions on the editorial boards of several prestigious international journals.Throughout his illustrious career, Dr. Hawley has been honored with esteemed awards such as the Medical Research Council of South Africa's RC Scholarship and the University of Cape Town's JW. Jagger Postgraduate Scholarship. His commitment to excellence and groundbreaking research continues to shape the landscape of exercise science and nutrition.About Vikas Singh:Vikas Singh, an MBA from Chicago Booth, worked at Goldman Sachs, Morgan Stanley, APGlobale, and Reliance before coming up with the idea of democratizing fitness knowledge and helping beginners get on a fitness journey. Vikas is an avid long-distance runner, building fitpage to help people learn, train, and move better.For more information on Vikas, or to leave any feedback and requests, you can reach out to him via the channels below:Instagram: @vikas_singhhLinkedIn: Vikas SinghTwitter: @vikashsingh101Subscribe To Our Newsletter For Weekly Nuggets of Knowledge!
Embark on a journey through the human body with Ashley Freeman, a luminary in the field of human physiology, who makes a special appearance on our podcast to unravel the mysteries of skeletal muscle metabolism, especially within the context of cancer patients. From her transition from nursing assistance to researching the depths of muscle systems, Ashley's narrative is not just educational but peppered with laughter and a nod to her surprising TikTok fame. Together, we tackle the marvels of muscle structure, dissecting the complex processes from the macroscopic fascicles to the sarcomeres' microscopic dance during muscle contraction, all while busting myths about protein powders and the need for steroids.Get ready to flex your brain as well as your biceps, as we sift through the best practices for muscle growth, emphasizing the synergy between resistance training, nutrition, and the often-overlooked superhero of recovery—sleep. Ashley expertly guides us on how to optimize protein intake and why that shaker bottle might just be your best gym buddy. Our conversation isn't limited to the gym goers; we also shed light on the intricacies of electrolyte balance, making sense of the sodium-potassium pump, and calling out the health marketing industry on their sometimes misleading narratives.As we draw a close to this enlightening session, hydration takes center stage. We critically evaluate the strategies behind sports drinks, like Prime and Liquid IV, and even play with the idea of launching our own hydration line—because who wouldn't want a cute bottle that might also contain a fruit infuser? Lastly, we demystify creatine monohydrate supplementation, highlighting its benefits and dismissing the myths that often follow this well-researched supplement. So tune in, not just for the knowledge bombs dropped by Ashley but for a healthy dose of critical thinking and a few laughs along the way.Support the showYou can find us on social media here:Rob TiktokRob InstagramLiam TiktokLiam Instagram
On Performance People this week, Dr Gabrielle Lyon, a functional medicine practitioner and the founder of the Institute for Muscle-Centric Medicine®. Dr Lyon is a best selling author, a nationally recognized speaker and media contributor specializing in brain and thyroid health, lean body mass support, and longevity. She talks extensively about why looking after skeletal muscle is fundamental to the ageing process, why the most successful entrepreneurs don't do highs and lows and provides a plan for getting started today. Hosted on Acast. See acast.com/privacy for more information.
Welcome to the Critical Oxygen Podcast! In this episode Dr. Robby Jacobs and I talk about the importance of skeletal muscle in predicting endurance performance. We focus on the significance of capillaries, myoglobin, and mitochondria in endurance performance, along with research comparing predictors of performance. Here is a link to my master's publication discussing predictors of performance - https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14342 If you have a question or topic you want us to address, leave a comment! Follow Phil on Instagram - https://www.instagram.com/criticalo2 Interested in testing, courses, or other long form content check out the critical oxygen website - https://www.ctiricaloxygen.com OUTLINE: 0:00 – Introduction 1:04 – Remote Physiology Assessment in Kona 6:12 – Training Zone Adjustments 7:01 – Monitoring and Adapting Training Zones 8:05 – Expanding Testing to Running and Rowing 9:29 – Challenges in Implementing Treadmill Assessments 10:00 – Availability of Remote Testing 11:35 – Ultra Marathon Nutrition Strategy 15:04 – Despair in Training vs. Ultra Marathon 16:52 – Gut Training Experiment with Milk 20:05 – Carbohydrate Intake and Fuel Oxidation 24:59 – Shifting Focus Back to Predictors of Performance 25:24 - Importance of Capillaries, Myoglobin, and Mitochondria 25:58 - Mitochondrial Function as a Key Predictor of Performance 26:15 - The Skeletal Muscle and Capillary Myoglobin Mitochondria Axis 26:33 - Research on Traditional Predictors of Performance 27:11 - Comparison to a 40-Kilometer Time Trial 28:13 - Diverse Study Participants 29:00 - V02 Max Test Methodology 30:24 - V02 Max Verification at 110% 32:02 - Near-Infrared Spectroscopy (NIRS) Calibration 33:02 - Arterial Occlusion and Cuffing Protocol 36:01 - Validation of Cuffing Protocol 39:11 - Personal Experiences as a Participant 43:05 - Regenerative Medicine and Mesenchymal Cell Injections 48:16 - The Benefits of Regenerative Medicine? 49:01 - Back to the Predictors of Performance 49:32 - The 25-Kilometer Time Trial 50:25 - The Role of Oxygen in Muscles 51:53 - Traditional Predictors of Performance 53:04 - Near-Infrared Derived Predictors of Performance 54:09 - The Implications of the Study 57:00 - Oxygen Delivery and Utilization 58:02 - The Significance of NIRS Measurements 1:00:03 - Shifting Oxygen Balance in Muscle 1:00:28 - The Importance of Robust Mitochondria 1:02:07 - Summary: Oxygenation in Working Muscle 1:03:36 - The Role of Mitochondria in Complex Life
Full article: https://www.ajronline.org/doi/10.2214/AJR.23.29889 This podcast from George Vilanilam, MD focusses on sarcopenia and its assessment using CT scans. Sarcopenia is often assessed using the Skeletal Muscle Index (SMI), which is calculated by dividing the Skeletal Muscle Area (SMA) at the third lumbar vertebra (L3) by the patient's height squared. However, this study aimed to determine whether there's a more accurate way to scale muscle area relative to patient height and to explore how this might affect the ability of SMI to predict all-cause mortality.
Dr. Anurag Singh joins Dr. Stephanie to shed light on the potential health benefits of Urolithin A. This compound, found in foods such as pomegranate, raspberries, pecans, and walnuts, has been linked to improved muscle function, cardiovascular health, brain cognition, skincare, and more by boosting mitochondrial function.Learn where Urolithin A is produced in the body, who benefits from it, and its impact on various aspects of life, from the immune system to brain health. Discover the science behind this innovative compound and the dedication to research and development that sets it apart from traditional supplements. Don't miss this eye-opening conversation with a true game-changer in the field of aging and wellness.In this episode, you will learn about the science and research behind Urolithin A and how it's revolutionizing the way we approach aging. Tune in and discover the key to a healthier, more vibrant life with this fascinating discussion.Resources mentioned:Impact of the Natural Compound Urolithin A on Health, Disease, and Aging - https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(21)00118-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1471491421001180%3Fshowall%3DtrueConnect with Dr. Singh on:https://www.instagram.com/timelinenutrition/ https://www.amazentis.com/https://ch.linkedin.com/in/asingh041https://twitter.com/asingh04Episode Overview:0:00:00 The Connection Between Mitochondria and Immune Health0:01:18 Introduction to the Game-Changing Compound: Urolithin A0:04:34 Introduction to Dr. Anurag Singh and Urolithin A0:07:22 Urolithin A as a Postbiotic and Its Impact on Health0:10:11 Gut Microbiome Diversity and Richness in Urolithin A Production0:12:41 Possibility of Changing the Environment to Enhance Urolithin A Production0:15:28 Urolithin A's Influence on Skeletal Muscle and Mitophagy0:18:04 Measuring Improvement in Mitophagy with Urolithin A0:21:08 Urolithin A's Impact on Metabolic Function and Lipid Markers0:26:31 Urolithin A Supplementation Improves Skeletal Muscle Strength and Endurance0:31:13 Improved Recovery for Amateur Athletes0:34:16 Urolithin A as a Post-Workout Supplement0:36:53 Urolithin A's Effects on Mitophagy for Disc and Joint Health0:39:43 Joint and Muscle Health: Mitophagy and Inflammation0:42:56 Reduction in Redness and Photo Damage0:52:13 Safety Evaluation and FDA Approval of the Molecule0:55:14 Therapeutic Intervention and Environmental ConsiderationsWe are grateful to our sponsors:Equip is the easiest way to support healthy joints and tissues, and support recovery after an injury. Put one scoop of Equip Foods Collagen and 1 scoop of their pre-workout in water before an early morning workout - and then make a post-exercise shake with their Prime Protein. Go to https://equipfoods.com/better and the code: BETTER for 20% off
An Interview with Kevin Winthrop_ Three Questions About COVID 19 Assessment and Treatment of Cardiovascular Risks in Rheumatoid Arthritis Biologics in RA_ Mechanisms of Delivery Over Mechanisms of Action_ (1) Cannabinoid Receptor in RA Patients Impact of Tofacitinib on Skeletal Muscle in RA No Increased Mortality in Patients with RA Receiving Checkpoint Inhibitors Non-TNFi b_tsDMARDs vs. TNFi in RA-ILD Older RA Patients Just Aren't Getting Treated People with RA and Long COVID Had Worse Pre-COVID RA Symptoms Reproductive History, HPV Vaccination Among Women with SLE and RA Teledidactic vs On Campus Training in Musculoskeletal Ultrasound The SMART Study_ Split Dose Oral Methotrexate Unravelling the Mechanism of Clots with JAK Inhibitors Upadacitinib for Pain_ Is That Real_ Will CAR T Cells also treat RA_
Another TYK2 Ticks the Boxes Head to Head Comparison of Tofacitinib and TLL-018 in RA Impact of Tofacitinib on Skeletal Muscle in RA Is Point of Care Ultrasound Hocus Pocus_ JAK1 TYK2 in RA Monitoring the Effect of Therapy with a...Smart Watch_ Non-TNFi b_tsDMARDs vs. TNFi in RA-ILD Simulated JAK Trials to Counter ORAL Survelliance Treatments in SpA Unravelling the Mechanism of Clots with JAK Inhibitors Upadacitinib for Pain_ Is That Real_
Cannabinoid Receptor in RA Patients Cardiac Troponin T and MACE Events in RA Imaging Updates in SpA Impact of Tofacitinib on Skeletal Muscle in RA Teledidactic vs On Campus Training in Musculoskeletal Ultrasound Treatments in SpA
We are so honored to have James Barry on the podcast today! James Barry began his culinary career as a private chef for celebrities including Tom Cruise, George Clooney, and Barbra Streisand, among others. He co-authored recipes in Margaret Floyd's "Eat Naked" and subsequently co-authored "The Naked Foods Cookbook". Recently, James introduced "Pluck", a pioneering organ-based seasoning, offering a tasty and convenient method for people to incorporate organ meats into their meals. I not only LOVED this conversation, but I really admire his story as well! He is incredible! Topics: 1. Origins of Pluck Seasoning - Inspiration behind Pluck - How the idea originated 2. Historical Consumption of Organ Meats - Role in traditional diets - Decline in modern Western diets 3. Culinary Aspects of Organ Meats - Flavors and experiences added to dishes 4. Nutritional Profile - Distinction of organ meats from other animal parts 5. Myths and Misconceptions - Debunking common myths - Addressing concerns about toxins 6. Health and Nutritional Benefits - Key reasons to incorporate organ meats into diets 7. Understanding Pluck Seasoning - Definition and ingredients - Organ meats used in the seasoning - Preparation process and safety measures 8. Incorporating Pluck in Everyday Cooking - Usage recommendations for those new to organ meats Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
You're getting a house call from MY PERSONAL DOCTOR and she's giving you the science-backed strategies on how to live LONGER, BETTER and STRONGER.
Today, we cover something that everybody wants at some level or another—muscle. If you want to live a long time and you've fallen for the plant based nonsense science that's out there to sell more Froot Loops, well, you're heading in the wrong direction from a longevity perspective. The cold, hard truth is that skeletal muscle mass drives longevity.Dr. Gabrielle Lyon joins the show today to flex her own intellectual muscles on protein intake, reframing the hallmarks of aging, supplementing aminos, healthy fascia, and a whole lot more. You've heard her talk about these things online probably as much as I have; she calls what she does Muscle Centric Medicine—and as you can imagine, I am fully on board. She's looking at aging in exciting new ways in her new book, Forever Strong, which is packed with science-based strategies for aging well.We respectfully lock horns on a few subjects near and dear to our hearts—ranging into symptomatology vs. muscle health, key flaws in modern skeletal muscle research, where to draw the line on veganism, unlocking longevity through diet, and more—before landing on our shared responsibility to the greater community to share these insights for the common good.Dr. Gabrielle Lyon is a true heavyweight in the space and my dear friend, backing up her immense aptitude with real life results as a biohacker seemingly aging at a slower pace than one might expect. It's a pleasure to welcome her to the show today.(02:38) Correlation Between Aging & Skeletal Muscle Mass • Read: Forever Strong by Dr. Gabrielle Lyon• Dr. Gabrielle's informed background in geriatric medicine• Modern symptomatology vs. skeletal muscle health• Reframing the hallmarks of aging• 40 Years of Zen• Gaps in modern skeletal muscle measuring • A New Whole-Body MRI Scan Sees Everything - Raj Attariwala M.D., Ph.D. #989• Optimizing genetic potential • Benefits to weight training as a young person • How much weight training is ideal?• Read: The One-Minute Workout by Martin Gibala• Skeletal muscle as body armor (23:30) To Protein or Not to Protein? There's No Question• Protein intake with regard to longevity• Mythbusting mechanistic target of rapamycin (mTOR)• Kevin Hart ends up in wheelchair after being ‘dumbest man alive'• One possible benefit to animal protein restriction • Considering protein instead as its 20 amino acids • Benefits to collagen supplementation• Read: The Switch by Mr. James W. Clement• Not-So-Science Fiction: Extending Your Healthspan Gets Real - James Clement #608(37:29) Applying the Science: Everyday Tips & Practices• Spacing amino acids throughout the day • Dr. Lyon's longevity protocol• Eating earlier for circadian alignment• Evidence hedging intermittent fasting • Negative impact of alcohol on aging (47:42) Fascia, Muscle & Hernias: What's the Connection?• Importance of fascia in aging • Recommendations to avoid hernia surgery• Explaining the tensegrity principle as it relates to muscle health • Value of functional movement practice • Link between the virus and an increase in mast cells (50:26) Best Proteins & Why You Shouldn't Go Vegan• Dr. Lyon's recommended animal protein powders • Why vegan farts are the real problem • Other important bioavailable nutrients in animal protein • Veganism in younger/older people• Wielding the responsibility to educate • Dave's health journey and inspiration• Supplementing amino acids • Read: Forever Strong by Dr. Gabrielle LyonResourcesDave Asprey's NEW Book ‘Smarter Not Harder' is out now: https://daveasprey.com/books Website: drgabriellelyon.comRead: Forever Strong by Dr. Gabrielle LyonInstagram: @drgabriellelyonPodcast: The Dr. Gabrielle Lyon ShowYouTube: Dr. Gabrielle LyonFacebook: Doctor Gabrielle LyonX: @drgabriellelyonThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
So many of us are struggling with our weight or just struggling to step into the next phase of life with vitality. On today's episode, my guest is going to flip the idea of weight and health on its head and focus on the importance of skeletal muscle and how she believes that muscle is key to longevity. Muscle is an endocrine organ and it has so much to do with blood sugar regulation, energy production, and hormone regulation. So, let's dive into today's conversation with Dr. Gabrielle Lyon!You'll hear more about:How the physical body determines how the rest of the body functions The one thing most people have in common when it comes their bodies (hint: it might just surprise you!)Three big keys to why muscle is so important Why the "recommended" daily amounts for vitamins and minerals are NOT nearly enough (and how much you should be striving to get!)The importance of the first and last meals of the dayAnd so much more!Grab Dr Lyon's new book here: Forever Strong: A New Science-Based Strategy for Aging Well (Book): https://drgabriellelyon.com/forever-strong/More about Dr. Lyon:Well-respected functional medicine practitioner, Dr. Gabrielle Lyon, is the founder of the Institute for Muscle-Centric Medicine®. Dr. Lyon is a nationally recognized speaker and media contributor specializing in brain and thyroid health, lean body mass support, and longevity. Dr. Gabrielle Lyon is board certified in Family Medicine and completed a combined research and clinical fellowship in Geriatrics and Nutritional Sciences at Washington University in St. Louis. She completed her undergraduate training in Nutritional Sciences: Vitamin & Mineral Metabolism at the University of Illinois. Dr. Lyon is a subject matter expert and educator in the practical application of protein, types, and levels to health, performance, aging, and disease prevention. She has continued to receive mentorship from Dr. Donald Layman, Ph.D. over the course of two decades to help bring protein metabolism and nutrition from the bench to the bedside.Her clinical practice services the leaders, innovators, mavericks, and executives in their respective fields. Dr. Lyon works closely with the Special Operations Military and has a private practice that services patients worldwide.Connect with Dr Lyon: Dr. Lyon's Website: https://drgabriellelyon.com/Dr Lyon's Instagram: https://www.instagram.com/drgabriellelyon/Dr Lyon's Facebook: https://www.facebook.com/doctorgabriellelyon/If you want to lose weight without the risk of gastroparesis, muscle loss, and rebound weight gain, then use MetaboLift instead!Struggling with balancing your hormones? Grab your copy of the The Gutsy Gynecologist's Guide to Balancing your Hormones: https://drtabatha.com/free-guide/Support your hormone balance- EnergyLift! Connect with Dr. Tabatha:Work with us: Schedule a callDr. Tabatha's Facebook: https://www.facebook.com/DrTabathaDr. Tabatha's IG: https://www.instagram.com/thegutsygynecologist/Dr. Tabatha's YouTube: https://www.youtube.com/channel/UCWea1x1abLERehb5yn_nfow
Dr Glenn McConell chats with Professor Russell Hepple from the University of Florida, USA. He is an expert on muscle mitochondria. We tend to think of the mitochondria as the powerhouse of the cell. As Russ clearly explains there is a lot more going on than only this. It is very important that the inner mitochondrial membrane remains impermeable. However, there are situations such as aging, ischemia reperfusion injury, muscle dystrophies and perhaps cancer/chemotherapy where calcium and reactive oxygen species can build up and affect this permeability. This mitochondrial permeability transition is a major focus of Russell's research. Very interesting work and an informative chat. Russell does very well to simplify a complicated area of research. Twitter: @HeppleRuss0:00. Introduction1:50. The mitochondria beyond “the powerhouse”3:30. Free radicals/reactive oxygen species can be good4:50. ROS production at rest and during exercise7:50. Chronically elevation of ROS8:55. Inner mitochondrial membrane is impermeable10:30. Elevated calcium levels in the cell/mitochondria15:40. Mitochondrial permeability transition pore17:40. Swelling and rupture of mitochondria20:10. What causes the increase in calcium etc/aging23:40. Ischemia reperfusion injury during a heart attack26:00. Cyclophilin D, calcium and mitochondrial permeability transition28:30. Muscular dystrophy and mitochondrial permeability transition31:15. Interactions between calcium and ROS35:00. Diabetes and mitochondrial permeability transition37:00. Aging and mitochondrial function/volume (sex differences)42:35. Can calcium precipitate in the cell?43:53. Can assume skeletal muscle responds similarly to other cells47:00. Aging and mitochondrial permeability transition48:55. Aging and the neuromuscular junction51:58. Deinnervation and the muscle endplate54:58. Cancer and mitochondrial permeability transition57:35. Chemotherapy and mitochondrial permeability transition1:00:15. Takeaway messages1:01:49. Outro (9 seconds)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise's effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: glenn.mcconell@gmail.comSubscribe to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice
Professor Bishop is a world leader in muscle exercise physiology, with over 250 scientific publications. He leads the Skeletal Muscle and Training research group at Victoria University in Australia. The focus of his research group is to examine how diet, exercise, and genes interact to regulate skeletal muscle adaptations. Throughout his career, Professor bishop has held many different and important leadership positions within the exercise science community in Australia. He was the youngest-ever president of Exercise & Sport Science Australia (ESSA). He has been named one of the top 25 influencers of exercise & sports sciences in Australia. He has twice been on the Excellence in Research Australia (ERA) panel. He was made a fellow of three different organizations, Exercise and Sports Science Australia (ESSA), the American College of Sports Medicine (ACSM), and the European College of Sports Science (ECSS). Professor Bishop is now a director of the Victorian Institute of Sport (VIS) and an assistant editor of Medicine and Science in Sports and Exercise.David's TwitterPodcast with Renee Eastman on Physiological TestingMighty Mitochondria with Iñigo San MillánEffects of Dietary Supplements on Adaptations to Endurance TrainingPrinciples of Exercise Prescription, and How They Influence Exercise-Induced Changes of Transcription Factors and Other Regulators of Mitochondrial BiogenesisGet my deep dive newsletter Research Essentials for UltrarunningBuy Training Essentials for Ultrarunning on Amazon or Audible.Information on coaching-https://www.trainright.comKoop's Social MediaTwitter/Instagram- @jasonkoop
While exercise helps us stay healthy, what is happening on the molecular level? Matthew A. Romero, Ph.D., shares his work to understand how muscle in general and other cells specifically are transcriptionally regulated by exercise and how this affects their general behavior and how this is impacted by diseases such as obesity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39033]
While exercise helps us stay healthy, what is happening on the molecular level? Matthew A. Romero, Ph.D., shares his work to understand how muscle in general and other cells specifically are transcriptionally regulated by exercise and how this affects their general behavior and how this is impacted by diseases such as obesity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39033]
While exercise helps us stay healthy, what is happening on the molecular level? Matthew A. Romero, Ph.D., shares his work to understand how muscle in general and other cells specifically are transcriptionally regulated by exercise and how this affects their general behavior and how this is impacted by diseases such as obesity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39033]
While exercise helps us stay healthy, what is happening on the molecular level? Matthew A. Romero, Ph.D., shares his work to understand how muscle in general and other cells specifically are transcriptionally regulated by exercise and how this affects their general behavior and how this is impacted by diseases such as obesity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39033]
On this week's episode, WHOOP VP of Performance Science, Principal Scientist, Kristen Holmes is joined by health expert Dr. Gabrielle Lyon. Dr. Lyon is the founder of the Institute for Muscle-Centric Medicine and is a nationally recognized speaker and media contributor specializing in brain and thyroid health, lean body mass support, and longevity. Kristen and Dr. Lyon will discuss a patient's story that unlocked Dr. Lyon's research (3:15), where things start to go wrong for people's health (6:35), what skeletal muscle does and the behaviors needed to build it up (11:35), the relationship between protein and skeletal muscle (13:50), how to find the right amino acids (17:20), Dr. Lyon working with patients to get proteins (21:45), fasting and eating throughout the day (26:50), getting adequate levels of protein as a vegetarian (31:25), protein and resistance training helping to prevent disease (34:25), having tough conversations about health (37:25), Dr. Lyon's journey in writing her book (43:30), Dr. Lyon's ideologies and practice (47:15), dealing with doubters and skeptics (53:55), talking with loved ones about health (57:40), and tips on improving muscle tissue health (1:01:25).Resources:Dr. Lyon's Website Dr. Lyon's TEDx TalkEPISODE 45 The Science of Recovery: How to be More Resilient | Kristen Holmes Support the show
Episode Highlights With JJWhy we should all stop trying to lose weight and why she says this after decades as a weight loss expertThe problems with some of the weight loss trends right nowThings that have helped her thrive and feel amazing in her 50s!The importance of skeletal muscle for maintaining a healthy body compositionMuscle loss vs fat lossWhat metabolic adaptation is and why this is importantCreatine, protein, and resistance trainingReasons not to focus just on the scaleReframing the conversation about health and weight especially with our kidsWhat you measure you can improveHow to use a DEXA scan to understand your body compositionWhy it is more dangerous to be under muscled than over fat and why where the fat is mattersYes, you can lose fat and put on muscle at the same time and how to put on muscle as the priorityWhy we need more protein as we age, not lessThe problem with some ways people try to intuitive eat and how to learn to do this by nourishing your bodyWhy you need to be healthy to drop fat, not drop fat to be healthyLess than 6% of the population is metabolically healthyHow to restore insulin sensitivity with gaining muscle and sleepWhy we burn fat well when we are sleeping and why fasted workouts might not be great for womenLet's stop trying to be smaller and to take up less space and focus on getting strongerMuscle is your metabolic Spanx and a sugar sponge to handle carbsHow to use HRV as a tool to see what is helping you and use it to improve your nervous systemWhy you should absolutely be taking creatine and why it is a secret weapon for womenThere is no amino acid reservoir, you are going to break down muscle if you don't get enoughExercise is a great way to get autophagyAn ending challenge for you (try it!)Resources We MentionMindshareJJ's YouTube video on OzempicGrip Strength TesterLevelsKion AminosKion CreatineMitopureThink and Grow Rich by Napoleon Hill
Skeletal Muscle is Elastic, Excitable and Contractile. Does Electric Stimulation Acupuncture at the Motor Points of the muscle restore those qualities after injury has made the muscle short, weak and inhibited? The German word for "numb" is "taub". I think muscle inhibition may be due to the muscle being deaf, not listening to the nerve signals. What if it's not the nerve, but the muscle that is causing muscle inhibition?
Maintaining muscle mass is crucial for healthy aging, as it is closely linked to overall physical function and quality of life. As we age, our bodies naturally experience a decline in muscle mass and strength, known as sarcopenia. This loss of muscle mass can lead to a range of negative health outcomes, including decreased mobility, increased risk of falls and fractures, and decreased metabolic rate. Additionally, loss of muscle mass can contribute to chronic conditions such as obesity, diabetes, and cardiovascular disease. By developing an epigenetic clock for skeletal muscle, Dr. Voisin and her colleagues have identified specific methylation patterns that are associated with muscle aging. This research not only sheds light on the biological mechanisms behind sarcopenia, but may also provide new targets for interventions aimed at preserving muscle mass and function in older adults.In this week's Everything Epigenetics podcast, Dr. Sarah Voisin and I focus on her 2020 paper which describes her development of a human muscle-specific epigenetic clock that predicts age with better accuracy than the pan-tissue clock. Yes - you heard that right… better accuracy than Dr. Steve Horvath's 2013 clock. Dr. Voisin and I also chat about the importance of skeletal muscle and how this relates to epigenetics and aging, the power of machine learning, and how identifying which methylation positions change as we age may give us insight into the underlying reason as to WHY we age rather than just HOW. She is now focused on creating an atas of epigenetics for all human tissues at the cellular level by combining 75,000 DNA methylation profiles across 18 tissues. In this episode of Everything Epigenetics, you'll learn about: How Dr. Voisin got her start in statistics and biology The importance of skeletal muscle tissue and how this relates to Epigenetics and AgingWhen to start exercising and moving your bodyThe importance of weight lifting How often we should be moving our body Why Dr. Voisin decided to develop this type of Epigenetic ClockThe limitations of the Horvath 2013 Clock as it relates to skeletal muscle The complications of data miningThe importance of collaboration and data sharing How Dr. Voisin created her muscle-specific Epigenetic Clock The power of machine learningHow the muscle clock outperforms Dr. Steve Horvath's 2013 pan-tissue ClockDr. Voisin's epigenetic wide association studies (EWAS) she performedDifferentiated methylated positions (DMPs) in this studyDifferentiated methylation regions (DMRs) in this studyThe utility/application of the skeletal muscle Epigenetic ClockDr. Voisin's next big project (I'm so excited about her next project!!!) MEAT (muscle epigenetic age test)Where to find Dr. Voisin:Email: sarah.voisin@vu.edu.au Twitter: https://www.vu.edu.au/research/sarah-voisinGitHub account:https://github.com/sarah-voisinSupport the showThank you for joining us at the Everything Epigenetics Podcast and remember you have control over your Epigenetics, so tune in next time to learn more about how.
Accumulation of fat in the liver (hepatosteatosis) and muscle (myosteatosis) affects normal physiological functioning, leading to poorer health outcomes. But what is the concurrence of these two conditions in the general population, and are there common underlying mechanisms? Professor Julie Pasco and colleagues at Deakin University and Barwon Health in Australia investigate these metabolic alterations in a population-based study providing vital clinical insight. Their results suggest fat build-up in the liver seems to co-exist with fat accumulation in skeletal muscle, and such individuals are more likely to have sarcopenia (reduced skeletal muscle mass and strength).Read more in Research OutreachRead the original article: https://doi.org/10.1007/s00223-021-00939-9
I discuss the role of skeletal muscle for our physical health and cite an article by Gabrielle Dore entitled. Muscle is the Cornerstone of Our Longevity. I also explain how physical health can affect relationships.Do you have questions or comments?Please contact me: rtosguthorpe@gmail.comWant more info about my books and talks?Go to my website: https://www.russelltosguthorpe.com/Want to order a book? Just go to Amazon and type in Russell T. Osguthorpe Want to access my YouTube channel:https://youtube.com/@russellt.osguthorpe497Want know more about the music on this podcast? We are blessed to have M. Diego Gonzalez as a regular contributor of songs he has arranged, performed, and recorded especially for this podcast. My wife and I became acquainted with Diego when he was serving a as missionary in the Puerto Rico San Juan Mission. We were so impressed with his talent, we asked if he would compose and perform songs for Filled With His Love. He thankfully agreed. Hope you enjoy his work!Want to boost your mood and make someone's day?Go to the App store on your iPhone, and download the app—Boonto.Want a good introduction to my book? Morgan Jones Pearson interviewed me on the All-In Podcast, and it was one of the top 10 episodes of 2022. Here's the link:https://www.ldsliving.com/2022-in-review-top-10-all-in-podcast-episodes-from-the-last-year/s/11190...
Today host Rachel talks to Breast Cancer Surgeon Doreen Wiggins MD about yoga and breast cancer. In this episode, Dr. Wiggins helps us to better understand our breast cancer risk and shares some simple actions that we can take to reduce that risk. She also explains what steps we can take to improve the potential outcome of cancer treatment if we are diagnosed with cancer and shares how we can modify our yoga practice to better suit our needs both before and during cancer treatment. Listen to this episode to learn how yoga can reduce your risk of cancer, tips for identifying lymphedema warning signs in yoga students, and how the lymphatic system is like the Cinderella system of the body. Show Notes: Current statistics on breast cancer [3:33] Risk levels for breast cancer [4:47] Preventing breast cancer [8:33] Defining hormone-positive breast cancers [12:50] Exercises to ward off breast cancer [15:40] How can yoga reduce the risk of cancer [17:47] Yoga during cancer treatment [20:24] Asana during cancer treatment [25:50] Tips for yoga practice before and after radiation therapy [32:26] Managing the fear of cancer recurrence with yoga [34:33] Understanding lymphodema [38:59] Tips for yoga teachers identifying lymphedema warning signs [41:13] Doreen's takeaways [44:04] Links Mentioned: Watch this episode on YouTube Moving Beyond the Fear of Cancer Recurrence by Dr. Doreen Wiggins Insights and Reflections on COVID-19 from a Surgeon by Dr. Doreen Wiggins The Benefits of Skeletal Muscle for Cancer Prevention & Survival by Dr. Doreen Wiggins You can learn more about this episode, and see the full show notes at YogaMedicine.com/podcast-51. And you can find out more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts.
Besides its structural importance, muscle is metabolically active tissue that hugely impacts your health. Find out how losing weight may work against your metabolism and why it may be hard for you to lose weight.For more information on Dr. Vyvyane Loh visit https://www.vyvyanelohmd.comTime stamps:2:29 Importance of muscle3:14 Skeletal Muscle vs. Smooth Muscle4:40 Skeletal Muscle structure7:42 Basal Metabolic Rate (BMR)10:00 BMR difference between muscle and fat16:06 Sarcopenia17:04 Health risks with sarcopenia18:57 Criteria for Sarcopenia19:46 Mass & strength correlation in obesity vs non-obesity states21:08 Strength measurement21:51 Performance measurement (TUG)23:54 Mass measurement24:32 FFM vs. LBM vs. SMM26:44 Variable components of LBM27:12 Guidelines for Body Comp by DXA31:14 Anabolism vs. Catabolism32:41 Anabolic Resistance34:54 Catabolic Crises37:25 Covert Catabolic Crisis40:16 Dieting and Muscle Loss41:25 Bariatric Surgery, Weight Loss & LBM Loss46:03 Accelerated Muscle Loss, Diabetes and Sarcopenia50:15 Kidney Disease & Sarcopenia53:20 Cachexia56:00 How to preserve/gain muscle1:01:28 Wrap up
My guest today is the creator of Muscle Centric Medicine, Dr. Gabrielle Lyon. Board certified in family medicine, Dr. Lyon completed a research/clinical fellowship in Nutritional Science and Geriatrics. Dr. Lyon is a woman on a mission, and she wants us to build and keep our skeletal muscle system and make sure to consume enough protein. Gabrielle's message is clear and direct. As we age, we need to dose our protein to ensure the intake of vital amino acids. She is not asking you to become a bodybuilder and eat hunted meat all day long, but she is asking us to re-think how we are approaching some of our health habits. If you are interested in managing weight, living vitally, and avoiding chronic disease, then Dr. Lyon believes she has some of the answers. Has anyone ever said to you we should treat the Skeletal Muscle system like another important organ? Enjoy Connect with Gabby @gabbyreece | Linktree For show notes and past guests, please visit gabriellereece.com/podcast The Gabby Reece Show talks to top experts with the goal of extracting the best information you will need to navigate the universe of health, fitness, relationships, parenting, and business. Gabby keeps it simple but gets to the heart of the conversation with the hopes of providing you with realistic takeaways. Dr. Gabrielle Lyon Helpful Links: www.drgabriellelyon.com Instagram: @drgabriellelyon & @freedomreads_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Layne Norton, Ph. D., is a scientist, pro natural bodybuilder, raw elite powerlifter, and physique coach, among other things. He received his BS in Biochemistry, and his PhD in Nutritional Sciences. He is a current IPF and USAPL world and national record-holder in squat (668 lb).“I always tell people, I don't think I would've had the success I did in business or social media or academia if I hadn't done weightlifting because that taught me so much about other things in life.” —Layne NortonIn this episode we discuss:MUSCLE/ WEIGHT LIFTING The keys to preserving muscle and losing fat Why is skeletal muscle so important for longevity and brain health?What's really driving muscle growth: intrinsic vs. systemic factors, IGF, and hormone signalingThe important role of inflammation from exerciseWOMEN vs MENMost studies done on men Women training on empty stomach Clarifying the role of cortisol—a misunderstood hormoneProtein and amino acids amounts needed to build muscle SCIENTIFIC INTEGRITY What is a scientific paperHow to read scienceWhat is fake and what is not FOOD/ DIETEnergy: are all calories equal? How much we are burning va how much we actually burn Mascros Genes / blood work and specific diets Tracking meals and counting calories Find Layne here:YouTubeInstagramWebsiteSponsors:Eight Sleep: $150 off - NEUROhttps://www.eightsleep.com/neuroHVMN- 20% DISCOUNT - NEUROhttps://hvmn.me/NeuroYou can follow me or contact me here ---Newsletter: https://bit.ly/3ewI5P0Instagram: louisanicola_Twitter : louisanicola_YouTube: Louisa NicolaThe information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Neuro Experience podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Layne Norton, Ph. D., is a scientist, pro natural bodybuilder, raw elite powerlifter, and physique coach, among other things. He received his BS in Biochemistry, and his PhD in Nutritional Sciences. He is a current IPF and USAPL world and national record-holder in squat (668 lb). “I always tell people, I don't think I would've had the success I did in business or social media or academia if I hadn't done weightlifting because that taught me so much about other things in life.” —Layne NortonIn this episode we discuss:MUSCLE/ WEIGHT LIFTING The keys to preserving muscle and losing fat Why is skeletal muscle so important for longevity and brain health?What's really driving muscle growth: intrinsic vs. systemic factors, IGF, and hormone signalingThe important role of inflammation from exerciseWOMEN vs MENMost studies done on men Women training on empty stomach Clarifying the role of cortisol—a misunderstood hormoneProtein and amino acids amounts needed to build muscle SCIENTIFIC INTEGRITY What is a scientific paper How to read science What is fake and what is not FOOD/ DIETEnergy: are all calories equal? How much we are burning va how much we actually burn Mascros Genes / blood work and specific diets Tracking meals and counting calories Find Layne here:YouTube InstagramWebsite Sponsors:Eight Sleep: $150 off - NEUROhttps://www.eightsleep.com/neuroHVMN- 20% DISCOUNT - NEUROhttps://hvmn.me/NeuroYou can follow me or contact me here ---Newsletter: https://bit.ly/3ewI5P0Instagram: louisanicola_Twitter : louisanicola_YouTube: Louisa NicolaThe information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Neuro Experience podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
He's back! And this time Erik Ledin is back with help for the men. TRT (testosterone replacement therapy) is something that has 4X in the last decade. Thanks to more education around this topic, men are now becoming more optimized thanks to wellness clinics popping up all over the country. Erik works with Revive MD. They have several locations and now serve via telemedicine To apply for coaching with Erik or Lean Bodies Consulting If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser and Castbox. Sign up for the next Follow-Through Challenge Follow me on Social Media:Amy on IGAmy on Facebook Resources:AmyLedin.comLean Bodies Consulting (LBC)LBC University
Your skeletal muscles make up nearly half your body weight, and while they are widely recognized as critical for locomotion, their lesser-known functions include increasing metabolism, protecting neurological health, and more. Dr. Lyon recently joined me for a live Q&A-style webinar hosted by CrossFit Health with a focus on why it's important to maintain adequate muscle mass to promote long-term health, and I'm sharing that content here. Dr. Lyon is a functional medicine physician specializing in muscle-centric medicine, which focuses on the key role skeletal muscle plays in health and longevity. By using high-quality protein diets, supplements, and resistance training, she helps a variety of patients, from those suffering with sarcopenia or prediabetes to elite military operators, reduce chronic disease risk and improve longevity. You can join me live for next month's webinar featuring Dr. George Slavich on January 19th at 7 PM Eastern. Keep an eye out on CrossFit.com for registration details. Related Episodes: Ep 183 - Robb Wolf on The Case for (Better) Meat Ep 204 - Dr. Gabrielle Lyon on Maximizing Muscle Mass for Health To learn more about CrossFit Health and how to get involved as a healthcare provider or patient visit health.crossfit.com. If you like this episode, please subscribe to Pursuing Health on iTunes and give it a rating or share your feedback on social media using the hashtag #PursuingHealth. I look forward to bringing you future episodes with inspiring individuals and ideas about health every Tuesday. Disclaimer: This podcast is for general information only, and does not provide medical advice. I recommend that you seek assistance from your personal physician for any health conditions or concerns.