Podcasts about early development

In this newscast: A Sitka Grand Jury indicted a Juneau man Thursday for allegedly assaulting two men at a demonstration in downtown Sitka; Fairbanks police evacuated one of the city's Fred Meyer locations on Saturday evening, after a deactivated mortar shell was left in the grocery store's bathroom; The University of Alaska Board of Regents introduced changes to the University's antidiscrimination policy around hiring and recruitment on Friday; Alaska students' test scores improved modestly last school year, according to results released Friday by the Department of Education and Early Development; One of Petersburg's most popular trail systems on Mitkof Island recently got an upgrade with help from out-of-towners.

Mike Chmielewski conversed with Dr. Deena Bishop, Commissioner of the Alaska Department of Education and Early Development, at the Alaska State Fair. Their wide-ranging conversation about education in Alaska encompassed everything from current legislative developments to assessment testing.

Send us a textSummaryIn this conversation, the host and guest discuss the intricacies of basketball training, the importance of mentorship, and the challenges faced by young athletes today. They delve into the need for better training facilities and the significance of individual growth and networking in the sports community. Additionally, they explore insights into sports betting, predictions for upcoming football seasons, and share personal experiences with betting strategies. The conversation wraps up with food recommendations and a call to action for aspiring athletes.Chapters00:00 Welcome to Vegas: Life and Training02:22 Building Trust and Relationships in Coaching04:45 The Evolution of Training Methods07:01 The Need for Structured Training Facilities09:48 The Importance of Early Development in Basketball11:57 Adjusting to Life in Vegas13:45 Sports Betting Insights and Predictions15:43 Player Props and Best Bets18:07 Food and Culture in VegasTakeawaysThe importance of mentorship in youth sports.Repetition is crucial for skill development in basketball.Building trust with athletes enhances training effectiveness.Modern athletes are influenced by social media trends.Training should focus on fundamental skills and consistency.Facilities for youth training are lacking in many areas.Individual growth is essential for networking in sports.Sports betting requires careful analysis and strategy.Understanding player dynamics is key in betting.Food plays a significant role in sports culture and community.TakeawaysThe importance of mentorship in youth sports.Repetition is crucial for skill development in basketball.Building trust with athletes enhances training effectiveness.Modern athletes are influenced by social media trends.Training should focus on fundamental skills and consistency.Facilities for youth training are lacking in many areas.Individual growth is essential for networking in sports.Sports betting requires careful analysis and strategy.Understanding player dynamics is key in betting.Food plays a significant role in sports culture and community.Support the show

In this episode of Bitcoin for Corporations, host Pierre Rochard is joined by Mike Belshe, CEO of BitGo. Mike shares his journey from Netscape and Google to pioneering Bitcoin custody solutions. They discuss the evolution of multi-sig, fiduciary duty, cold storage, and how institutions protect billions in Bitcoin. Belshe explains why proof of reserves and market structure matter for Bitcoin's future. This is a must-watch for anyone serious about Bitcoin security.

Dr. Deena Bishop, Commissioner of Education and Early Development in the Dunleavy Administration, is on the show talking about what's good and what's bad in the current educational environment in Alaska.With the recent override of Dunleavy's veto by a crazy number of Republicans who voted to disregard accountability, this is a hot topic. Tune in and stay informed.Support the show

Scientists did not find harmful toxins in mussels collected from Kachemak Bay, and the Alaska Department of Education and Early Development is appealing a federal decision that could cost the state $80 million – and potentially undermine equitable funding among Alaska schools.

The Alaska Department of Education and Early Development, or DEED, is proposing changes that would limit how local governments can contribute to their schools. Skagway's school superintendent says that while these changes wouldn't harm his district in the short term, they are an overreach that will undermine public education. KHNS reporter Melinda Munson has the […]

In this newscast: The City and Borough of Juneau is inviting developers, nonprofit and tribal governments to apply for grants or loans from its affordable housing fund; Two black bear cubs were electrocuted to death after climbing a utility pole in downtown Juneau Monday night; The Alaska Department of Education and Early Development is appealing a federal decision that could cost the state $80 million; A coalition of schools and advocacy groups, including several Alaska school districts, is suing the Trump administration over its decision to withhold about $6.8 billion in federal education funds approved by Congress; The state's only med school program started this week with its biggest cohort

In this episode of Founded & Funded, Madrona Partner Vivek Ramaswami sits down with Jared Palmer — designer, developer, and founder of Turborepo (acquired by Vercel), and former VP of AI at Vercel. Jared walks through his unique path from Goldman Sachs to Vercel, and how he combined finance, design, and engineering to create beloved developer tools like Formik, TSDX, and Turborepo, and v0. The two dive deep into: Why vertical integration is the future of AI-native dev platforms The founding and launch of Vercel's v0.dev How Vercel is positioning for a world with 700M code-generators, not just 28M developers What makes teams and products move fast Why “text-to-app” will soon become “text-to-business” Whether you're a founder building dev tools, a product leader thinking about AI-native apps, or a developer curious about the future of your craft — this episode is packed with lessons and foresight. Subscribe and listen now! Transcript: https://bit.ly/4kQWVig Chapters:  (00:00) Introduction (01:40) Jared Palmer's Early Career in Finance (04:40) Transition to Design and Freelancing (07:12) Building a Career in Open Source (11:46) Creating TurboRepo (13:47) Joining Vercel (15:27) Adjusting to Corporate Life (17:37) The Power of Transparency in Teams (17:50) Building a Thriving Team Environment (19:08) Origins of v0 (19:29) Early Development and Challenges (21:38) Key Innovations and Prototypes (22:58) Launch and Rapid Growth (25:32) Navigating a Competitive Landscape (30:02) Future of AI and Software Development

In today's Midday Report with host Terry Haines:Alaska's former U.S. Rep. Mary Peltola is suing the owners of the aircraft that her late husband was piloting at the time of his death. A coalition of schools and advocacy groups is suing the Trump administration over its decision to withhold some $6.8 billion in federal education funds. And the Alaska Department of Education and Early Development is appealing a federal decision that could cost the state $80 million.Photo: Eugene "Buzzy" Peltola Jr.

Saoud Rizwan and Pash from Cline joined us to talk about why fast apply models got bitter lesson'd, how they pioneered the plan + act paradigm for coding, and why non-technical people use IDEs to do marketing and generate slides. Full writeup: https://www.latent.space/p/cline X: https://x.com/latentspacepod Chapters: 00:00 - Introductions 01:35 - Plan and Act Paradigm 05:37 - Model Evaluation and Early Development of Cline 08:14 - Use Cases of Cline Beyond Coding 09:09 - Why Cline is a VS Code Extension and Not a Fork 12:07 - Economic Value of Programming Agents 16:07 - Early Adoption for MCPs 19:35 - Local vs Remote MCP Servers 22:10 - Anthropic's Role in MCP Registry 22:49 - Most Popular MCPs and Their Use Cases 25:26 - Challenges and Future of MCP Monetization 27:32 - Security and Trust Issues with MCPs 28:56 - Alternative History Without MCP 29:43 - Market Positioning of Coding Agents and IDE Integration Matrix 32:57 - Visibility and Autonomy in Coding Agents 35:21 - Evolving Definition of Complexity in Programming Tasks 38:16 - Forks of Cline and Open Source Regrets 40:07 - Simplicity vs Complexity in Agent Design 46:33 - How Fast Apply Got Bitter Lesson'd 49:12 - Cline's Business Model and Bring-Your-Own-API-Key Approach 54:18 - Integration with OpenRouter and Enterprise Infrastructure 55:32 - Impact of Declining Model Costs 57:48 - Background Agents and Multi-Agent Systems 1:00:42 - Vision and Multi-Modalities 1:01:07 - State of Context Engineering 1:07:37 - Memory Systems in Coding Agents 1:10:14 - Standardizing Rules Files Across Agent Tools 1:11:16 - Cline's Personality and Anthropomorphization 1:12:55 - Hiring at Cline and Team Culture Chapters 00:00:00 Introduction and Guest Intros 00:00:29 What is Klein? Product Overview 00:01:42 Plan and Act Paradigm 00:05:22 Model Evolution and Building Klein 00:07:40 Beyond Coding: Klein as a General Agent 00:09:12 Why Focus on VS Code Extension? 00:11:26 The Future of Programming and Agentic Paradigm 00:12:34 Economic Value: Programming vs. Other Use Cases 00:16:04 MCP Ecosystem: Growth and Marketplace 00:21:30 Security, Discoverability, and Trust in MCPs 00:22:55 Popular MCPs and Workflow Automation 00:25:30 Monetization and Payments for MCPs 00:37:53 Competition, Forks, and Open Source Philosophy 00:40:39 RAG, Fast Apply, and Agentic Simplicity 00:50:11 Business Model and Enterprise Adoption 00:57:04 Background Agents, Multi-Agent Systems, and CLI 01:00:41 Context Engineering and Memory 01:12:39 Team, Culture, and Closing Thoughts

We look at the history of Christianity in Australia during early settlement from 1770-1901.Your support sends the gospel to every corner of Australia through broadcast, online and print media: https://vision.org.au/donateSee omnystudio.com/listener for privacy information.

In this newscast: The Alaska Department of Education and Early Development has opened the public comment period for a proposed regulation change that redefines what counts as a local contribution for school districts; A cargo ship carrying thousands of vehicles that caught fire off of the Western Aleutians sank Monday amid salvage operations in the North Pacific Ocean; Skagway officials agreed to send a response protesting the plan to build a ferry terminal north of Juneau's current terminal; A Klukwan mother and son travelled to Washington D.C. to protest a federal bill that would likely include cuts to Medicaid; A proposed ordinance to criminalize camping in Anchorage's public spaces brought a huge crowd to the city's Assembly meeting 

In this podcast episode, host Michelle Frechette welcomes Carrie Dils, Mika Epstein, and Ryan McCue to discuss their roles in the WordPress community and the new FAIR project. The group explores FAIR's mission to create a federated independent repository system for WordPress plugins and themes, focusing on decentralization, community-driven moderation, inclusive governance, and privacy. They address challenges like supporting premium plugins, reducing environmental impact, and fostering global participation. The episode highlights FAIR's collaborative, open-source approach and invites listeners to get involved through GitHub and community meetings, aiming to shape a more innovative and inclusive WordPress ecosystem.Top Takeaways:FAIR Is Reimagining Plugin Discovery and Trust for WordPress: FAIR is building a more open, decentralized ecosystem for WordPress plugin discovery—empowering both end users and developers. By enabling verified directories and authenticated plugin listings (via methods like DNS verification), FAIR provides an alternative to the limitations of the WordPress.org repo, while increasing transparency, user safety, and trust.Community Participation Is Central to FAIR's Success: The FAIR initiative is deeply community-driven. Contributors are encouraged to get involved through GitHub Discussions, introduce themselves, offer help, or join working groups. The leadership team is intentionally building these groups based on people's skills and availability, rather than predefined roles—making FAIR flexible, inclusive, and open to evolving needs.FAIR Encourages Innovation Outside Traditional WordPress Constraints: The project provides an alternative path for plugin creators who may not want to follow the traditional WordPress.org model (e.g., having to release a free version first). With FAIR, creators can request to be listed in aggregator directories that are more flexible, values-aligned, or niche-focused—fostering innovation and lowering barriers to entry.FAIR Is Still in Early Development—and Actively Growing: While the FAIR plugin and protocol are live (accessible via fair.pm), the ecosystem is in its formative stages. The team is prioritizing essential needs (the “MVP”) and building infrastructure to support future growth in documentation, marketing, design, development, and user testing. They welcome feedback on plugin issues, conflicts, and ideas, encouraging broad experimentation and iteration.Mentioned in the Show:FAIRLinkedIn LearningAwesome MotiveLez Watch TVHuman MadeAspire PressGravatarLinux Foundation ProjectBlueskyWPCCBlack PressMastodon DrupalCourtney RobertsonAutomatticMediaWikiMonster InsightsGravity FormsFastly

In this episode of the Epigenetics Podcast, we talked with Petra Hajkova from the MRC Laboratory of Medical Sciences about her work on epigenetics research on mammalian development, highlighting DNA methylation, histone modifications, and TET enzymes, along with her journey in molecular genetics and future research on epigenetic maintenance. Dr. Hajkova's early work focused on DNA methylation and resulted in innovative collaboration that allowed her to develop bisulfide sequencing techniques. We discuss her transition to the UK, where she began working in Azim Surani's lab at the University of Cambridge. Dr. Hajkova describes the excitement of researching chromatin dynamics in the mouse germline, leading to significant findings published in Nature. Her story highlights the intense yet rewarding nature of postdoctoral research as she navigated the complexities of working with embryos for the first time. As her research progressed, Dr. Hajkova established her own lab at the MRC London Institute of Medical Sciences, where she became a professor in 2017. We delve into her investigations on the differences between embryonic stem cells and embryonic germ cells regarding their distinct developmental origins. Dr. Hajkova outlines the challenges she faced in understanding the mechanisms behind global DNA demethylation in germline cells and the role of hydroxymethylation during early development. The discussion further covers her exciting findings regarding the specific functions of TET enzymes and their regulatory roles in maintaining epigenetic states. We explore her recent research published in Nature, which provides insights into the transition from primordial germ cells to gonocytes, emphasizing the significance of various epigenetic mechanisms in germline development.   References Hajkova P, Ancelin K, Waldmann T, Lacoste N, Lange UC, Cesari F, Lee C, Almouzni G, Schneider R, Surani MA. Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature. 2008 Apr 17;452(7189):877-81. doi: 10.1038/nature06714. Epub 2008 Mar 19. PMID: 18354397; PMCID: PMC3847605. Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science. 2010 Jul 2;329(5987):78-82. doi: 10.1126/science.1187945. PMID: 20595612; PMCID: PMC3863715. Hill PWS, Leitch HG, Requena CE, Sun Z, Amouroux R, Roman-Trufero M, Borkowska M, Terragni J, Vaisvila R, Linnett S, Bagci H, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, Pradhan S, Hajkova P. Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte. Nature. 2018 Mar 15;555(7696):392-396. doi: 10.1038/nature25964. Epub 2018 Mar 7. PMID: 29513657; PMCID: PMC5856367. Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P. Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742. doi: 10.1038/s41586-021-04208-5. Epub 2021 Dec 8. PMID: 34880491.   Related Episodes Epigenetic Mechanisms of Mammalian Germ Cell Development (Mitinori Saitou) Epigenetic Reprogramming During Mammalian Development (Wolf Reik) DNA Methylation and Mammalian Development (Déborah Bourc'his)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Episode 321: Understanding Baby Milestones: A Pediatric PT's Guide to Early Development with Dr. Allison Mell, PT, DPTThis week on the Untethered Podcast, Hallie welcomes Dr. Allison Mell, a pediatric physical therapist with a deep passion for child development. Allison shares her journey from general physical therapy to specializing in infant development, focusing on empowering parents with the tools and knowledge to support their child's growth. The conversation dives into essential early milestones such as tummy time, rolling, crawling, and walking, emphasizing the quality of movement over just meeting checklists. The episode also tackles the recent removal of certain milestones from the CDC guidelines and the implications for early intervention and parental confidence. If this episode has resonated with you in some way, take a screenshot of you listening, post it to your Instagram Stories, and tag Hallie @halliebulkinIn this episode, you'll hear:Allison's transition into pediatric physical therapy and her mission to support families.The importance of recognizing and supporting quality of movement in early development.Tummy time as a foundational activity for motor skills and strength building.Practical, everyday strategies for encouraging movement and milestones at home.Discussion on rolling and how it can impact sleep and comfort.The effects of CDC milestone changes on early detection and intervention.Barriers parents face when seeking developmental evaluations and services.Encouragement for parents to trust their instincts and advocate for their child's needs.Whether you're a parent, provider, or simply passionate about early childhood development, this episode is packed with valuable insights and support!LINKSGet to know Dr. Allison on Instagram. Check out her website: https://www.totsontarget.com/Be part of our Myo Fam! Join us inside The Myo Membership: www.themyomembership.comBecome a Certified Myofunctional Therapist™ (CMT®). Enroll here: www.themyomethod.comReady to turn your "myo eyes" on? Join our webinar: https://www.feedthepeds.com/myo-webinarDownload a Free F.A.S.T. Myo Screening Packet Here: FastMyoScreening.comFind a myofunctional therapist: www.themyodirectory.comConnect with Hallie on Instagram, Facebook & LinkedINHaven't left a review yet? Click here and thank you, as always, for being a listener!Want to watch more of the episode? Click here Hosted on Acast. See acast.com/privacy for more information.

In this newscast: The local advocates who filed a petition with the City and Borough of Juneau last month to put harder limits on cruise ship tourism have withdrawn it; The Juneau Assembly passed an ordinance mandating the Juneau Police Department release body-word camera footage no more than 30 days after a city police officer shoots someone; Another Ketchikan school board member stepped down, following the district's board president, superintendent and another board member; It's still not clear why the Alaska Department of Education and Early Development failed a federal test that saves the state millions of dollars; Juneau residents held a tree-planting ceremony in honor of Arbor Day yesterday.

In this newscast: The Juneau School District Board of Education appointed Steve Whitney to the board on Saturday; Senator Lisa Murkowski has introduced a bill that would reauthorize funds for landslide monitoring projects across Southeast Alaska; The Alaska Department of Education and Early Development failed a test that allows it to include millions of federal dollars towards its contributions to education funding; Tribal leaders from across the country spoke out last week at a U.S. Senate hearing against changes within the Department of Health and Human Services; Curious Juneau: What's the story behind the Fiddlehead Cookbook's North Douglas chocolate cake?

In this newscast: A German Shepherd who was on the lam for nearly three months has been captured to returned to her family; The Alaska Department of Environmental Conservation says 400,000 gallons of process water spilled at a large lead and zinc mine in Northern Alaska yesterday; The Alaska Department of Education and Early Development is considering whether to reduce the amount of money local governments can give to school district, but a new bill would allow local governments to continue to fund school districts as they have been; Juneau's city-owned ski area expects to run a deficit for the foreseeable future, and their plan to dig out of the deficit relies heavily on revenue from a gondola that has yet to be built; Lawmakers rejected two of Gov. Mike Dunleavy's nominees for state boards and commissions in a joint session of the state House and Senate yesterday

Mitch Bach sat down with João Perre Viana, the founder of Walking Mentorship, to talk one thing we tour operators are all familiar with: walking.But not many of us design week-long trips where all you do is walk. Sometimes alone. Sometimes in a group. That's it. Beyond some shared meals and moments, there isn't much of a plan. Each group takes on a different spirit, but it's all guided by a mentor who along the way tries to facilitate and gently foster personal transformation. What that looks like is up to the individual guest.This conversation veered away from the nitty-gritty of business, and towards diving into the importance and magic of what we do as experience creators.For more show notes, visit tourpreneur.com. And be sure to join nearly 20,000 tour operators in our Facebook group!1. Introduction to Walking Mentorship [00:00:09]Joao's background and origins in PortugalIs Walking Mentorship a tour company?2. Joao's Personal Journey and Spark for Walking Mentorship [00:01:16]The first Camino de Santiago in 1993The impact of the walk and self-discoveryRealization of a calling to this work3. Founding and Early Development of Walking Mentorship [00:04:23]Corporate career delay and returning to the ideaEmail to “fools, friends, and family,” and pilot programsEarly feedback and attempts to give up on the idea4. The Nature of Walking Journeys as Transformational Experiences [00:07:14]Layers of experience: curiosity, physicality, purpose, self-understanding, spirituality, cultureDoors in a room analogy for guiding participant journeys5. Participant Freedom, Responsibility, and Structure [00:12:06]Emphasis on total freedom and responsibilityRare participant withdrawal and the ethos behind the program6. Difference Between Typical Travel and Mentorship Walking Journeys [00:13:10]Critique of traditional, structured, checklist-driven toursDeprogramming guests and creating space for transformation7. Risk, Challenge, and Your Personal “Everest” [00:17:26]Meaning of risk (internal vs. external threats)The “wolves” participants face within themselvesEnsuring physical and psychological safety8. Common Motivations and Unique Outcomes [00:19:55]The universal quest or search among participantsEvery individual's unique journey and needs“There is no replay” principle9. The Mentorship Structure and Methodology [00:22:20]Mentor's responsibilities and boundariesPreparing participants for returning homeStructured support with eventual independence10. Designing for Difficulty and Personal Growth [00:26:53]Backpack packing as a life metaphorBalancing physical challenge with adaptabilityReading the group and tailoring the journey11. Practical Aspects and Device Usage [00:32:22]Approach to phone/device use on programsFostering mindful interaction with technology12. Lessons for Day Tour Operators and Short-Form Experiences [00:35:16]Applying listening, eye contact, and personalization even to short toursOffering small but impactful experiences13. The Art of Listening and Asking Questions [00:40:04]Listening as a crucial guiding skillAsking questions through...

In this newscast: The federal government may soon return a traditional subsistence site connected to Douglas Island to its original tribal owners; The next season of the PBS KIDS show “Molly of Denali” will be the last for the foreseeable future. The team behind the award-winning children's TV show will stop working on new content. Molly of Denali is widely celebrated in Alaska because it features an Alaska Native lead character and showcases Alaska Native culture; The Alaska Department of Education and Early Development is considering whether to reduce the amount of money local governments can give to school districts. A new bill in front of state lawmakers would allow local governments to continue to fund school districts as they have been; State prosecutors say two Anchorage police officers were legally justified in the fatal shooting of a man in February who police say had barricaded himself in a Midtown hotel and threatened a woman and her four children.

Send us a textDr. Martin Brenner, DVM, Ph.D. is Chief Executive Officer and Chief Scientific Officer of iBio ( https://ibioinc.com/team/martin-brenner-dvm-ph-d/ ), a biotech company developing the next generation of cardiometabolic and obesity medicines to promote higher quality weight loss and enhance overall metabolic health and function, as well as a pipeline of therapeutic candidates in immuno-oncology for some of the most-difficult-to-treat cancers, including solid tumors in lung, colorectal, and breast cancer, head and neck cancer, pancreatic cancer and glioblastoma, a fast-growing brain tumor. Dr. Brenner has a strong history of success heading drug discovery and development teams at several of the world's leading pharmaceutical companies, including AstraZeneca, Eli Lilly and Company, Pfizer Inc., and Merck Research Laboratories. Most recently, Dr. Brenner served as the CSO at Pfenex Inc., which, using its patented Pfēnex Expression Technology® platform, created an advanced pipeline of therapeutic equivalents, vaccines, biologics and biosimilars. Pfenex was acquired by Ligand Pharmaceuticals Incorporated for approximately $516 million in October 2020. Previously, Dr. Brenner served as the CSO at Recursion Pharmaceuticals, Inc., a company focused on accelerating drug discovery for rare diseases and diseases with high unmet medical need. Prior to his time at Recursion, Dr. Brenner was Vice President and Head of Research & Early Development at Stoke Therapeutics, Inc., a biotechnology company using antisense oligonucleotides to increase gene expression for the treatment of rare diseases. Prior to Stoke, Dr. Brenner was Executive Director at Merck, where he built a biotech unit from scratch, focusing his team's research on diabetes and nonalcoholic steatohepatitis (NASH). Earlier in his career, Dr. Brenner was the Senior Director and Head of cardiovascular, renal, and metabolism (CVRM) biosciences at AstraZeneca. In addition, Dr. Brenner was an Associate Research Fellow at Pfizer where he led the islet biology and in vivo pharmacology in the CVMED Target Exploration Unit before assuming the role of Head of the Insulin Resistance Group.Dr. Brenner has a DVM, Veterinary Medicine, Ludwig-Maximilians-Universität München and a Ph.D., Pharmacology  Tieraerztliche Hochschule Hannover.#MartinBrenner #iBio #Cardiometabolic #Obesity #Medicines #WeightLoss #MetabolicHealth #ImmunoOncology #GLP1 #BispecificAntibodies #ArtificialIntelligence #TransformingGrowthFactorBeta #Myostatin #ActivinA #ActivinE #MuscleMass #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Want the secrets to building a resilient business and learn how to future-proof your entrepreneurial journey with insights from our guest, Phil Portman. Listen as Phil shares his inspiring transformation from a difficult upbringing to becoming a successful entrepreneur, motivated by the desire to secure a stable future for his autistic son. Discover the importance of moving from micromanaging to empowering your team and creating systems that ensure your business can thrive independently, even in your unexpected absence. Phil's personal anecdotes shed light on crucial strategies, including estate planning and key person life insurance, that safeguard your business legacy. Stay ahead of the curve in communication technology with our exploration of the rising trend of text messaging in the U.S., particularly among those under 50. Phil and I discuss the immediacy and convenience of text messaging in urgent scenarios, illustrated by personal stories. We also tackle the challenges posed by spam and phishing, unveiling how the industry, alongside Phil's company Textdrip, is innovating solutions like delivery tracking and spam prevention. This episode is a compelling blend of business wisdom and tech insights, designed to equip you with the knowledge to both secure your business operations and enhance your communication strategies.   Timestamps 00:00:00 - Introduction and Welcome to Business Legacy Podcast 00:00:37 - Phil Portman's Early Life and Motivation for Entrepreneurship 00:02:15 - Transition from Micromanaging to Empowering the Team 00:04:00 - The Importance of Estate Planning and Key Person Life Insurance 00:05:30 - Personal Anecdote: Business Associate's Health Crisis and Lessons Learned 00:07:00 - Strategies for Operational Resilience and Testing Systems 00:09:00 - Introduction to Text Messaging as a Preferred Communication Method 00:10:15 - Personal Experiences with the Convenience of Text Messaging 00:11:30 - Industry Challenges: Spam and Phishing in Text Messaging 00:12:51 - Textdrip's Innovative Solutions for Delivery Tracking and Spam Prevention 00:15:00 - Early Development and Challenges in Creating Textdrip 00:17:00 - Success in Targeting the Insurance Industry with Textdrip 00:18:45 - Advantages of Text Messaging Over Traditional Communication Methods 00:20:15 - Threats and Solutions for Future Text Messaging Security 00:22:30 - Ensuring High Deliverability and Accurate Reporting with Textdrip 00:24:00 - Case Study: Overwhelming Success of a Text Campaign 00:26:00 - The Importance of Personalized Customer Service at Textdrip 00:27:30 - Closing Remarks and Information on Trying Textdrip and Following Phil Portman   Episode Resources: Check out what Phil is up to at Textdrip here: https://textdrip.com/ Legacy Podcast: For more information about the Legacy Podcast and its co-hosts, visit businesslegacypodcast.com. Leave a Review: If you enjoyed the episode, leave a review and rating on your preferred podcast platform. For more information: Visit businesslegacypodcast.com to access the shownotes and additional resources on the episode.

Today, Frank Turek gives his best evidence against evolution. And he doesn't do well.Cards:Either God is Evil, or Doesn't Exist:https://www.youtube.com/watch?v=0g7Rl6zJbfYOriginal Video: https://tinyurl.com/2ybykceySources:Long-Term Follow-Up of Transsexual Persons Undergoing Sex Reassignment Surgery: Cohort Study in Sweden: https://tinyurl.com/ych994aeSection 5: Evolution, Climate Change and Other Issues: https://tinyurl.com/2lcvkhbzUnderstanding the Universality of the Genetic Code – Exploring the Biological Foundations of Genetic Diversity and Evolution: https://tinyurl.com/25hsd9tnUnderstanding COVID-19 mRNA Vaccines: https://tinyurl.com/22lhmlklTypes of Mutations: https://tinyurl.com/2ckj7aowThe Cambrian “Explosion”, Transitional Forms, and the Tree of Life: https://tinyurl.com/25mpphs2Dynamics of Dark-Fly Genome Under Environmental Selections: https://tinyurl.com/2c7kzlugGolden Rice FAQs: https://tinyurl.com/2yqol7ruAn operational definition of epigenetics: https://tinyurl.com/2a22fejuEpigenetics and Early Development: https://tinyurl.com/24ovcwotHow does epigenetics influence the course of evolution?: https://tinyurl.com/2yr9mo72Become a supporter of this podcast: https://www.spreaker.com/podcast/viced-rhino-the-podcast--4623273/support.

In this newscast: Alaska Supreme Court Chief Justice Susan Carney defended the court system's work and laid out plans for the future in a speech to state lawmakers; Juneau's Visitor Industry Director Alix Pierce shared data from an annual tourism survey that shows the conversation about the future of tourism's growth is far from over; An education compact is an agreement between tribal and state governments that allows tribes to run their own public schools, and Alaska's Department of Education and Early Development is working with tribes to kick start a compacting program and give tribes sovereignty over education; Alaska State Troopers arrested a Metlakatla man last week on six felony charges of sexual abuse of a minor, and they believe he may have had other victims

Send Kevin a Text MessageIn this episode of Don't Kill the Messenger, host Kevin Goetz sits down with Elizabeth Gabler, known for transforming literary works into cinematic successes. From her early days as an agent's assistant to becoming president of Fox 2000 and now Sony 3000 Pictures, Gabler shares insights from her remarkable career developing hit films like Life of Pi, The Devil Wears Prada, Mrs. Doubtfire, Marley and Me, and Where the Crawdads Sing.Early Career and Love of Reading (01:43)Gabler discusses her background in English literature and unexpected entry into entertainment, influenced by her early love of reading and her mother's influence as a librarian.United Artists and Early Development (10:12)The conversation explores her time at United Artists, working with industry legends like Jerry Weintraub and Billy Wilder, and developing projects like Roadhouse and Presumed Innocent that would later become successful films.Mrs. Doubtfire Development (13:30)Gabler shares the fascinating story of bringing Mrs. Doubtfire to the screen, including working with Robin Williams and director Chris Columbus, and overcoming initial skepticism about the project.Cast Away and Production Innovation (23:22)Discussion of the unique production process of Cast Away, including Tom Hanks' physical transformation and Robert Zemeckis making an entire other film during the production break.Life of Pi Journey (29:43)Elizabeth offers a detailed look at the challenging journey to bring Life of Pi to the screen, including Ang Lee's involvement and the innovative technical approaches required.Devil Wears Prada Casting (36:48)The pair discuss the casting process for The Devil Wears Prada, including securing Meryl Streep and Anne Hathaway, and the discovery of Emily Blunt.Current Projects and Personal Life (46:20)Gabler discusses her current project Klara and the Sun with director Taika Waititi and stars Jenna Ortega and Amy Adams, while also touching on personal aspects including the recent loss of her husband Lee.This intimate conversation reveals not just the mechanics of bringing books to screen, but the passion, persistence, and vision required to create lasting cinema. Gabler's deep love for storytelling and family themes runs throughout her work and this discussion, offering insights into how personal values can shape professional success.If you enjoyed this episode, please leave us a review or connect on social media. We look forward to bringing you more revelations from behind-the-scenes next time on Don't Kill the Messenger!Host: Kevin GoetzGuest: Elizabeth GablerProducer: Kari CampanoWriters: Kevin Goetz, Darlene Hayman, and Kari CampanoAudio Engineer: Gary Forbes (DG Entertainment) For more information about Elizabeth Gabler:Variety: https://variety.com/exec/elizabeth-gabler/IMDB: https://www.imdb.com/name/nm1992894/LinkedIn: https://www.linkedin.com/in/elizabeth-gabler-7b030a19 For more information about Kevin Goetz:Website: www.KevinGoetz360.comAudienceology Book: https://www.simonandschuster.com/books/Audience-ology/Kevin-Goetz/9781982186678Facebook, Twitter, Instagram: @KevinGoetz360Linked In @Kevin Goetz

What makes a great sports program and how can parents and booster clubs elevate the experience for everyone involved? Jenny Richardson, head coach of the Georgetown Lady Eagles Volleyball team, shares her journey of leading her team to the state semifinals. With 16 years of coaching experience, Jenny's expertise in fostering talent, community support, and teamwork sets her apart. Jenny highlights the importance of community involvement, early player development, and the irreplaceable role of a dedicated booster club. From hosting volleyball clinics for young athletes to maintaining strong relationships with middle school coaches, Jenny reveals strategies to build cohesive and goal-driven teams. Tune in to learn how creating a supportive, hard-working community can lead to sustained success in sports.    Key Takeaways:   (00:02) - Meet Jenny Richardson: Georgetown Lady Eagles Volleyball Coach (01:05) - The Importance of Community Support (01:59) -  Building a Successful Sports Program (03:33) -  Early Development and Coaching Strategies (05:02) -  2024 Season Highlights and Team Dynamics (06:40) -  Assistant Coach's Unique Perspective (08:16) - The Role of the Booster Club (13:34) -  Sun City Boosters: A Unique Support System (16:40) -  Rebuilding for the Future (18:25) -  Advice for Coaches and Booster Volunteers (22:56) -  Jenny's High School Experience and Lifelong Friendships   Resources: https://ghs.georgetownisd.org/departments/athletics/athletics-home/ghs-volleyball/coach-jenny-richardson  

On today's Midday Report with Host Terry Haines: The Alaska Board of Education and Early Development released a draft statewide cell phone policy for students. Gov. Mike Dunleavy on Wednesday praised a series of executive orders President Donald Trump issued shortly after taking office. And powerful winter storm systems are set to impact most of western, northern and interior Alaska from Thursday evening through the weekend. Photo: President Donald Trump signs an executive order at the White House supporting natural resource development in Alaska on Monday, Jan. 21, 2025 in Washington. (CSPAN)

How do we find the right dose in immune-oncology trials? Is the traditional “maximum tolerated dose” approach still enough, or should we also focus on efficacy? In this episode of The Effective Statistician, I talk with Teppo Huttunen, a seasoned statistician and co-founder of the boutique CRO, Estimeds. We uncover the shortcomings of the conventional three-plus-three design and explain how the Bayesian Optimal Interval (BOIN) design gives us more flexibility and better insights. Teppo shares practical tips on dose optimization and highlights the critical role statisticians play in shaping smarter, evidence-based decisions for phase two trials. If you want to learn how we can balance safety, efficacy, and practical challenges in oncology studies, this episode is for you!

Data drives MedTech growth, from the leanest startup to the world's most valuable pharmaceutical company. In Episode #36 of the MedTech Speed to Data Podcast, Key Tech's Andy Rogers discusses data-driven trends in medical technology with Anand Subramony, Eli Lilly's Vice President of Drug Delivery, Device, Connected Solutions & Innovation.Need to know·       Quarter-century perspective — After getting his PhD in chemistry and materials science from Purdue University, Subramony spent the next twenty-five years developing novel medical technologies for firms like Johnson & Johnson, Novartis, and AstraZeneca.·       Cutting-edge combination product development — Now at Eli Lilly, Subramony's team is responsible for combination product development, from early development through commercial development, for new delivery dosage forms.The nitty-grittySubramony drew upon his career-spanning perspective to discuss significant data-driven trends that impact the entire industry, not just Eli Lilly.One topic he raised in his conversation with Andy was using data to monitor disease state progression. Already an important element of fields like neurology and oncology, extensive data collection will become essential to a wider range of treatments. For many conditions, Subramony explains, disease state is a binary evaluation.“You can really understand disease state progression using digital biomarkers and collecting data throughout [the treatment],” Subramony said. “I think these are areas where there is a lot of potential.”Another data-driven trend Subramony discusses is the adoption of direct delivery therapies. When treating tumors and other conditions, off-target toxicity can cause unfortunate side effects. Genetic medicines, such as mRNA therapies, can target the cell surface, protect the cargo, and prevent endosomal escape.“It's going to disrupt the way we look at drug delivery from macroscopic pen auto-injector deliveries to microscopic, targeted deliveries where you need to take the therapeutic moiety into the site of action,” Subramony said.Data that made the difference:This episode's wide-ranging conversation covered many additional topics of interest to the MedTech community, including:GLP-1 treatments are “really transformative” for individual patients who can afford them. However, bringing costs down will depend on data demonstrating how lower obesity and healthier lifestyles reduce the overall burden on the healthcare system.For sensors and connected devices to go beyond “bells and whistles,” the industry must drive value from how we use that data. Relating compliance to efficacy, for example, makes moving patients from less effective to more effective therapies easier and faster.Continuous monitoring can improve healthcare outcomes but requires new data management practices to govern how much data is collected, who is collecting and viewing the data, and what are the privacy rules protecting patients. 

Could Plasmalogens Be the Key to Anti-Aging Science? In this episode of the Longevity podcast, I am welcoming  back Dr. Goodenow to discuss the incredible progress and updates in his pioneering work on plasmalogens. We explore the importance of plasmalogens in neurological development and their role in treating conditions like ALS, autism, and MS.  Plasmalogens are essential lipids found in the brain, heart, lungs, and human breast milk, crucial for early brain development and preventing neurodegenerative diseases like ALS, MS, and autism and we discuss the mechanics behind aging and diseases, stressing the importance of mitochondrial function, membrane structure, and the body's ability to repair itself.    BIO: Dr. Dayan Goodenowe is a pioneering researcher and biochemist with a profound impact on neurological and age-related diseases.  Known for his work with plasmalogens, Dr. Goodenowe has devoted over three decades to studying these critical molecules and their role in human health. His research has significantly advanced the understanding and treatment of neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and autism, as well as conditions like COVID-19 and inflammatory disorders.   To Purchase Plasmologens use this link https://prodrome.com/?ref=NAT25 or head over to Prodrome.com and use code NAT25 to save 25% off your purchase!   Thank you to our sponsors for making this episode possible: NEUROHACKER:  Visit qualialife.com/nathalie and use code NATHALIE VITALI SKIN CARE/RESTORACELL: Visit vitaliskincare.com/discount/Nathalie20 and use code Nathalie20 to save on your order.   LVLVUP: Use code NAT15 to save 10% off at lvluphealth.com/                            Find more from DR DAYAN GOODENOWE: Website: drgoodenowe.com Instagram: @drdayangoodenowe and @prodromesciences   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat's Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance    What We Discuss: 01:22 The Importance of Plasmalogens 01:39 Our Advanced Infrastructure and Research 04:46 The Role of Plasmalogens in Early Development 06:28 Understanding Brain Development and Longevity 09:05 Restoring Health and Functionality 15:52 Parkinson's and Neurological Health 33:51 The Power of Plasmalogens in Neurogenesis 36:54 Understanding Plasmalogen Precursors 37:49 Historical Context and Importance of Plasmalogens 38:52 Challenges and Innovations in Plasmalogen Delivery 40:26 Impact of Plasmalogens on Inflammatory Diseases 41:53 Plasmalogens and Major Organ Functions 42:26 Plasmalogens in Cardiac Health and ALS 44:35 Mechanisms of ALS and Plasmalogen Therapy 50:37 Restoring Neuromuscular Function 58:02 Community Health Initiatives and Research   Key Takeaways: Plasmalogens are integral in early childhood brain development and maintaining the functionality of crucial organs like the heart and lungs. Plasmalogen deficiencies are linked to various severe health conditions, including neurodegenerative diseases. Adequate mitochondrial function is critical for mitigating the effects of chronic diseases, including autism and multiple sclerosis. Key nutrients include B vitamins, CoQ10, and carnitine.  

For more information, go to theconferenceforum.org 

DOI: 10.13056/acamh.13575 In this In Conversation podcast, Professor Sam Wass is joined by Dr. Celia Smith to discuss the science-facing findings of their JCPP Annual Research Review “‘There, the dance is – at the still point of the turning world' – dynamic systems perspectives on coregulation and dysregulation during early development” and the implications of their findings for practitioners. Learning Objectives 1. Brief overview of the methods used to study early child-caregiver interactions. 2. How new measurement techniques is driving new theory. 3. An overview of the clinical interactions currently available focused on child-caregiver interaction in the 0-3 age range. 4. Insight into six key areas relating to different processes of coregulation and dysregulation in the parent-infant pair. 5. What the reviews find in terms of cultural bias, especially as ideas around caregiver and infant interactions are often based around wester ideals, and how this can be addressed.

“What a lot of people don't quite understand about plant-based meat is that you have to understand the industry that you are replacing.” —Christie Lagally    The plant-based meat industry is at a pivotal moment, with innovative companies harnessing the power of technology to transform the way we think about sustainable protein. By seamlessly combining cutting-edge manufacturing processes and high-quality products, these visionaries are paving the way for a future where plant-based alternatives are not just viable, but the preferred choice for consumers, institutions, and the planet. At the forefront of this revolution is Christie Lagally, the CEO and Founder of Rebellyous Foods. A mechanical engineer by trade, Lagally has leveraged her expertise to develop game-changing technology that makes plant-based meat production faster, better, and more affordable than ever before. In this episode, Justine and Christie dive into the challenges of building a business around plant-based alternatives, developing the technology and market strategy to succeed, the impact of the hype cycle, funding challenges, addressing health concerns, and more.   Meet Christie:  Christie Lagally is the CEO and Founder of Rebellyous Foods, a manufacturing technology company working to make plant-based meat available and affordable for everyone. With a background as a mechanical engineer in the aerospace industry, Lagally transitioned to founding Rebellyous in 2017 to combine her personal values and professional expertise to address the negative impacts of industrial animal agriculture.  Under her leadership, Rebellyous has developed innovative processing equipment to produce high-quality, price-competitive plant-based meat products, with a focus on serving large-scale customers like school lunch programs.  Lagally is committed to creating a sustainable path forward for the meat industry to transition to plant-based production, driving positive change for the environment, human health, and animal welfare.   Website Facebook Instagram LinkedIn Connect with NextGen Purpose: Website Facebook Instagram  LinkedIn YouTube Episode Highlights: 05:01 Rebellyous Foods: Challenges and Early Development  13:05 The Hype Cycle and Its Impact 23:55 Health Concerns and Future Plans  35:06 Collaborations, Partnerships, and Exit Strategies  40:00 Future Opportunities   

We continue last week's discussion on exploration and how one can learn how to explore late in life. Download our free online video resource ⁠⁠⁠⁠⁠"The Main Signs of Attachment Disturbance" now. In this two-part video course, you'll learn how to identify the core disturbances, and how combining meditation and attachment work can help you move beyond the challenges and live a truly meaningful life. Begin your journey today at ⁠⁠⁠https://www.mettagroup.org/start-here⁠⁠⁠!

Paul Frambot, co-founder and CEO of Morpho Labs, explains how Morpho is a decentralized and permissionless lending protocol that allows users to create customized lending and borrowing pools. Unlike traditional DeFi platforms like Aave, Morpho externalizes risk management, giving users control over their risk exposure and liquidity. Frambot shares how Morpho started as a rate-optimizing solution and evolved into Morpho Blue, a more scalable protocol with over $1 billion in deposits. He discusses the advantages of building in Europe, Morpho's vision to make financial infrastructure a public good, and how fintech partnerships could drive future DeFi adoption. We also touch on Morpho's upcoming token launch and its long-term strategy to compete with other major DeFi protocols. 0:00 - Intro to Paul Frambot 0:30 - What is Morpho and How it Differs from Competitors 2:00 - Paul's Background and Entry into DeFi 3:30 - Early Development of Morpho Optimizer 5:00 - Transition to Morpho Blue and Permissionless Lending 8:00 - Managing Risk, Liquidity, and Customization 11:00 - Real-World Assets and New Use Cases in DeFi 14:00 - Challenges and Advantages of Building in Europe 18:00 - Morpho's Long-Term Vision: Financial Infrastructure as a Public Good 23:00 - Future of DeFi: Fintech Integration and Token Launch 28:00 - Competition with Aave and Growth Strategy 33:00 - The Role of Fintech in Scaling DeFi 38:00 - Long-Term Vision for DeFi and Fintech 43:00 - Morpho's Upcoming Tokenomics and Governance 48:00 - Future Trends and Adoption in DeFi 52:00 - Closing Thoughts and Paul's Outlook on DeFi This episode was sponsored by: NEAR: https://redactedbangkok.ai/?utm_source=thedefiant&utm_medium=referral&utm_campaign=defiant&utm_content=newsletter Stellar: https://stellar.org/soroban?utm_source=defiant&utm_medium=cpc&utm_campaign=defiant_podcast ✨ Check out our new website ✨ https://thedefiant.io/

On this episode we discuss exploration and how one can learn how to explore late in life. Download our free online video resource ⁠⁠⁠⁠⁠"The Main Signs of Attachment Disturbance" now. In this two-part video course, you'll learn how to identify the core disturbances, and how combining meditation and attachment work can help you move beyond the challenges and live a truly meaningful life. Begin your journey today at ⁠⁠https://www.mettagroup.org/start-here⁠⁠!

On this week's episode of Sense, by Meg Faure, we delve into the crucial topic of early development. Meg Faure welcomes Claire Stead, an educator and founder of Oliiki, to discuss the significance of the first 1000 days of life. The episode highlights the impact of early experiences, epigenetics, and the key developmental milestones that set the stage for a child's future. The Importance of the First 1000 Days Claire Stead explains why the first 1000 days, from conception to age two, are foundational for a child's development. These early years are when the brain undergoes rapid growth, laying the groundwork for all future learning and development. Stead emphasizes that this period not only shapes cognitive and academic outcomes but also emotional, social, and physical health. The environment and experiences during these critical years can influence factors like well-being, resilience, and stress responses later in life. Epigenetic's and Generational Impact A key theme of the episode is epigenetic's. The idea that environmental factors can switch genes on or off, influencing not just the individual but future generations. Stead shares fascinating research on how experiences during pregnancy and early childhood can affect gene expression, potentially impacting not only a child's health and development but also that of their grandchildren. This underscores the importance of a nurturing and stress-free pregnancy, not just for the mother but for the baby's future generations. Key Developmental Milestones The episode explores three pivotal developmental milestones: smiling, crawling, and pointing. Smiling is crucial for emotional connection, crawling is vital for physical and cognitive development, and pointing signifies communication readiness. Faure and Stead discuss why these milestones matter and how they contribute to a child's broader developmental trajectory. Practical Parenting Tips Listeners are offered practical tips to nurture their child's development. Stead emphasizes the importance of eye contact, time spent on the floor for motor development, and limiting distractions like screens to foster engagement and connection. This episode is essential listening for any parent or caregiver who wants to give their child the best start in life. Claire Stead provides valuable insights on how simple, daily interactions can lay the foundation for lifelong success. If you want to understand how early childhood development shapes your child's future, this episode is a must-listen.

In this episode of The Light Inside, we delve into the intricate world of emotional triggers and self-regulation. We all experience moments when a seemingly innocuous comment or situation sends us spiraling into an emotional storm. Whether it's a partner's remark or a social media comment, our emotions can distort reality, leading to unnecessary conflict and misunderstanding. We explore the concept of the autonomic ladder, a metaphorical escalator that represents our emotional states. Our guest, John Eli Gouray, provides insights into how our autonomic nervous system, through a process called neuroception, constantly scans our environment for cues of safety and danger. This system can trigger either a calm, parasympathetic response or an aroused, sympathetic response, often without our conscious awareness. John explains the three primary states of the autonomic ladder: 1. Dorsal Vagal State: Associated with feelings of shutdown, immobilization, and despair.2. Sympathetic State: Characterized by activation, anxiety, and a desire for movement or conflict.3. Ventral Vagal State: The state of safety, social connection, and calm. Exploring the concept of emotional triggers, this episode delves into how seemingly harmless interactions can escalate into overwhelming emotional storms. From conversations with partners to comments on social media, our reactions can be driven by our emotions, altering our perceptions and leading to unnecessary conflict. The episode questions why it's challenging to control these reactions and sheds light on the autonomic ladder, illustrating how we can quickly spiral into misunderstandings when triggered emotionally. 00:00:00 - Introduction to Emotional Triggers00:00:10 - Real-Life Examples of Emotional Triggers00:01:03 - Impact of Emotional Reactions00:01:24 - The Autonomic Ladder Explained00:02:06 - Sponsor Message: Mint Mobile00:03:42 - Understanding Nervous System Responses00:05:09 - The Role of Neuroception00:07:11 - Early Development of Emotional Patterns00:08:48 - Emotions vs. Feelings00:10:00 - Story Follows State00:11:32 - Inference and Transference in Emotional Responses00:14:10 - Autonomic Nervous System and Childhood Experiences00:17:17 - The Autonomic Ladder: Detailed Breakdown00:20:00 - Dorsal Vagal Response00:23:21 - Sympathetic State and Overachieving00:27:13 - Personal Story: Work and Self-Worth00:30:16 - Sympathetic Phase of Response00:33:31 - Motivations Behind Emotional Responses00:34:35 - Identifying Emotional States00:38:08 - Hypervigilance and Emotional Reactivity00:40:35 - Example: Walking Through a Dark Pathway00:41:13 - Ventral Vagal Response00:43:03 - Pets and Emotional Regulation00:44:31 - Intuitive Awareness of Emotional Triggers00:45:52 - Identifying Triggers and Glimmers00:48:04 - Physical Movement and Emotional Relief00:49:07 - Emotional Cleaning as an Outlet00:50:19 - Labeling and Stigmatizing Behaviors00:52:44 - Personal Experiences with Sun Exposure00:53:38 - Assumptions and Projections in Interactions00:54:33 - The Practice of Asking and Clarifying JOIN US ON INSTAGRAM: @thelightinsidepodcast SUBSCRIBE: pod.link/thelightinside https:www.thelightinside.site Credits: Featured Guest: John Eli Guray Music Score: Epidemic Sound Executive Producer: Jeffrey Besecker Mixing, Engineering, Production and Mastering: Aloft Media Executive Program Director: Anna Getz

Peter Burke, Minister for Enterprise, Trade and Employment, on a record 250 million euro allocation to an Enterprise Ireland scheme to provide funding for Irish companies in their early stages of development.

“An Appointment with Yourself” is the second class in a five part series on the Breath hosted by Pernilla Burke and Abdi Assadi. In this class we discuss  the importance of proper breathing techniques for mindfulness and emotional regulation.  We provide practical tools to increase awareness and create moments of pause in daily life. The class emphasizes that many people breathe shallowly from the upper lungs due to chronic anxiety. Abdi explains that shallow thoracic breathing suppresses emotions and disconnects us from our bodies. They advocate for "belly breathing," where the lower lobes of the lungs are filled, increasing oxygen intake and helping release repressed emotions. The class aims to help listeners re-train their breathing patterns, highlighting the physiological and emotional benefits of mindful breathing. Pernilla and Abdi's insights encourage incorporating these techniques into daily routines for improved well-being and conscious living. (00:00) Introduction: Introduction by Pernilla Burke and Abdi Assadi. Overview of the purpose of the Awakening 101 classes. (01:01) Importance of Breath: Discussion on the significance of breath for mindfulness. Brief mention of the personal journey with breathwork. (03:01) Shallow Breathing and Anxiety: Explanation of shallow thoracic breathing. Connection between anxiety and shallow breathing. (05:31) Belly Breathing Technique: Introduction to belly breathing. Explanation of how it fills the lower lungs. (07:31) Emotional and Physical Benefits: Benefits of proper breathwork on emotional regulation. Discussion on how breathing can help release repressed emotions. (10:01) Early Development of Breathing Patterns. How shallow breathing patterns develop from a young age. Impact of trauma on breathing. (12:01) Practical Tips for Daily Life: Practical tips for incorporating proper breathing into daily routines. Encouragement to practice mindful breathing for improved well-being. (14:01) Personal Experiences and Conclusion. Abdi and Pernilla share personal experiences with breathwork. Final thoughts and encouragement to viewers.

This week, I welcome Brent Leuthold back to the show to review Twisters in both a non-spoiler and spoiler feature review. Then, in this week's secondary review, we share our thoughts on Fly Me to the Moon. We also talk about recent news regarding Severance season 2, Bob Newhart's passing, a possible 24 movie, Noah Hawley's Alien: Earth, and more.   Timestamps   Show Start - 00:28 News - 05:43 Thoughts on Twister (1996) - 36:57   Feature Review   Twisters (2024) - 43:49 Spoiler - 1:15:29   Secondary Review   Fly Me to the Moon (2024) - 1:45:07   Closing the Ep - 2:03:38 Patreon Clip - 2:06:33   Related Links   Start Your Podcast with Libsyn Using Promo Code OBSESS '24' Film in Early Development at 20th Century, Produced By Brian Grazer Bob Newhart, Comedy Icon, Dies at 94 Russo Brothers Make Big Return To Marvel As They Eye Upcoming ‘Avengers' Sequels FX's ‘Alien' Series Wraps Filming, Showrunner Noah Hawley Promises “Something Special” ‘Severance' Season 2 Teaser Unveils 2025 Release Date and Gwendoline Christie's Mysterious New Character   Brent's Letterboxd Awake in the Dark Brent's Review of Twisters Brent's Review of Longlegs Brent's Review of Fly Me to the Moon   My 2024 Podcast and Writing Archive One Year of Criterion Channel - Dec 24, 2023 - Dec 23, 2024 Movies I Own But Haven't Watched/Rated Yet   Follow Us on Social Media My Letterboxd | YouTube | Facebook | Twitter/X Instagram | Threads | Bluesky | TikTok | Tiny's Letterboxd   Subscribe to the Podcast Apple Podcasts | Spotify | Audible   Support Us on Patreon for Exclusive Content Official OV Merch  Obsessive Viewer Obsessive Viewer Presents: Anthology Obsessive Viewer Presents: Tower Junkies As Good As It Gets - Linktree   Mic Info Matt: ElectroVoice RE20 into RØDEcaster Pro II (Firmware: 1.3.4) Brent: Earthworks ICON Pro in Google Meet   Episode Homepage: ObsessiveViewer.com/OV435   Next Week on the Podcast OV436 - Deadpool & Wolverine (2024) & TBD

In Season 2 Episode 33 of our Montessori Babies Podcast, I had the pleasure of chatting with Dr. Liraz all about boosting brain development in the early years! She is a neuroscientist and Mama who has a love for all things Montessori.This week we discussed:brain boosting from birth - 6 yearsbrain development beyond childhoodtangible tools to boost brain development everydayhow to support your own brain as a new MamaAnd more!Dr. Liraz's website: https://littleneurons.com2nd Live International Montessori SeminarSeptember 7, 2024 - 9:00 AM - Noon CDT - Live on ZoomDon't miss this upcoming high quality, hands-on International Montessori seminar! The amazing panel of speakers are ready to help you and your child take Montessori education to the next level. Come learn from the experts, win FREE Montessori prizes, and make new friends! Learn and earn $1000 worth of prizes in our raffle, including personalized coaching, educational books, innovative toys, and so much more!Connect with like-minded educators and parents passionate about Montessori education during our breakout sessions. **EARLY BIRD SPECIAL: **Enter LVLUP20 for a 20% discount at checkout.*SPACES ARE LIMITED!! *REGISTER NOW and receive a FREE GIFT here:

Send us a Text Message.Effect of Low-Dose Iron Supplementation on Early Development in Breastfed Infants: A Randomized Clinical Trial.Svensson L, Chmielewski G, Czyzewska E, Domellöf M, Konarska Z, Piescik-Lech M, Späth C, Szajewska H, Chmielewska A.JAMA Pediatr. 2024 Jul 1;178(7):649-656. doi: 10.1001/jamapediatrics.2024.1095.PMID: 38739382 Clinical Trial.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

New research finds that iron supplementation for low-risk breastfed infants born at term does not improve psychomotor development. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, MPH, and JAMA Pediatrics Associate Editor Alison Galbraith, MD, MPH, discuss infant iron supplementation with Martha Sola-Visner, MD, associate professor at Boston Children's Hospital and Harvard Medical School. Related Content: Effect of Low-Dose Iron Supplementation on Early Development in Breastfed Infants

Welcome to a new episode of The Founder Podcast. In this episode, we explore Alex Neist's journey from the depths of personal and professional despair to the heights of entrepreneurial success with Hostage Tape. Discover how a simple change in his sleep habits led to a profound transformation in his life and sparked the creation of a brand that's much more than just a product—it's a movement. Alex shares the incredible story behind Hostage Tape, revealing how it not only improved his own life but also promises to revolutionize sleep for millions. Highlights: "I'm building a billion dollar brand. It is—I know it is. I can see where it's going to be. And I know what the TAM is, I know what the opportunity is." "This isn't just tape. It's a movement." "I need something that I'm I love doing and I love building. I love building these companies." Timestamps: 00:00 - Introduction to Hostage Tape 02:08 - Origin Story of Hostage Tape 05:08 - Early Development of Hostage Tape 10:48 - Naming the 'Hostage' Brand 16:41 - Marketing and Brand Evolution 22:40 - Protecting Product Innovations 30:09 - Building a Brand Community 34:50 - Team Culture and Philosophy 42:17 - Future Vision and Strategy 45:15 - Influential Books and Resources Looking to scale your business? Want to learn directly from the same team that helped me sell my last business for 9 figures? Click this link below to check out how you can work with us. https://nextlevelhomepros.com/grow-home-service-vsl Join my community - Founder Acceleration ⁠https://www.founderacceleration.com ⁠Apply for our next Mastermind: h⁠ttps://www.thefoundermastermind.com⁠Golf with Chris h⁠ttps://www.golfwithchris.com⁠Watch my latest PodcastApple- ⁠https://podcasts.apple.com/us/podcast/the-founder-podcast/id1687030281S⁠Spotify- ⁠https://open.spotify.com/show/1e0cL2vI1JAtQrojSOA7D2⁠YouTube - @thefounderspodcast

Kacie and Gianna are joined by mom of four with a passion for helping kids learn and grow to their fullest potential, Heather Mrak. Heather shares the importance of movement for your baby's brain development and understanding how our primitive reflexes contribute to the process of maturing the brain. She has over ten years of experience using cutting-edge brain training techniques for children and is trained in Neurodevelopmental Movement Foundations (based on Dr. Mastagova and Dr.Harold Blomerg's work), Dr. Melillo's Brain Balance techniques, and Brain Gym® 101. She helps parents learn strategies and exercises that boost their baby's brain development in order to grow the strongest foundation possible for all learning.  Topics discussed in this episode: The seven intelligences The pivotal role that tummy time and crawling play in the early development Her personal journey through homeschooling and how movement-based interventions like Brain Gym supported her son's reading and writing skills Prenatal education: where to start before giving birth Essential connections between movement, attachment, and development,  The impact of environments like playpens versus restrictive containers on infant movement The importance of play: including risky play and integrating it as part of stimulative development The significance of recognizing and nurturing children's love languages Allowing children to face struggles to build self-esteem Connect with Heather: www.instagram.com/babysbestbrain www.babysbestbrain.com www.tiktok.com/@babysbestbrain101 Connect with Kacie & Gianna: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.motheruppod.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/motheruppod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@motheruppod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ View full show notes at ⁠⁠⁠www.motheruppod.com⁠⁠⁠⁠

A physician-scientist father shares his heartbreaking story of the death of his daughter who was diagnosed with Tay-Sachs disease and how it motivated him to become the CEO of JScreen to prevent this experience in other families.  Matt Goldstein is a physician-scientist and entrepreneur. He has founded companies, built R&D teams, and led strategy and execution of both pre-clinical research and clinical development. Prior to joining JScreen and Emory University, Matt was a Partner at Related Sciences, a venture creation firm. As an entrepreneur at Third Rock Ventures he spent a decade building and operating Third Rock portfolio companies. He was responsible for building and leading the Immunology program at Tango Therapeutics, the centerpiece of Tango's strategic multi-billion dollar partnership with Gilead Sciences, Inc. He also served as the development head for Tango's lead program which entered the clinic in 1H 2022. Matt was a co-founder of Neon Therapeutics leading Translational Medicine and Early Development through completion of their first clinical study and initial public offering. He is a graduate of Swarthmore College and the MD/PhD program at Stanford University, where he pioneered novel cancer immunotherapies in the lab of Ron Levy, MD. He completed his clinical training in Internal Medicine at Harvard Medical School, Brigham & Women's Hospital. He lives in Boston with his wife, Myra, their second daughter Kaia and son Ezra. His oldest daughter Havi died on January 20th, 2021 of Tay-Sachs disease. A quick update that during the episode Matthew mentioned there are 4,000 genetic counselors in the USA, this number has now surpassed 5,000.   During the episode, Matthew recommends the book Bearing the Unbearable: Love, Loss, and the Heartbreaking Path of Grief by Dr. Joanne Cacciatore.    Check out his wife, Myra's organization, Emotion, which is for grieving individuals to find community and cope with loss.    In our next episode we will chat with Myra about Emotion and her upcoming book, Fifty-Seven Fridays, which consists of memoirs from Matt and Myra, Havi's diagnosis, and how they celebrated her life.    Stay tuned for the next new episode of It Happened To Me! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”.    “It Happened To Me” is created and hosted by Cathy Gildenhorn and Beth Glassman. DNA Today's Kira Dineen is our executive producer and marketing lead. Amanda Andreoli is our associate producer. Ashlyn Enokian is our graphic designer.   See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com. 

Contents Podcast Panelists Additional Resources Transcript   In December 2023, we continued our Place Matters webinar series with our second installment: “Understanding Racism's Impact on Child Development: Working Towards Fairness of Place in the United States.” During the webinar, Stephanie Curenton, PhD, Nathaniel Harnett, PhD, Mavis Sanders, PhD, and Natalie Slopen, ScD, discussed their latest research, exploring how racism gets “under the skin” to impact children's development and how it contributes to unequal access to opportunity in the places where children live, grow, play, and learn. Together, they explored ways to dismantle systemic barriers and work toward solutions that promote healthy child development. The webinar discussion has been adapted for this episode of the Brain Architects podcast.  Panelists Stephanie Curenton, PhD (Moderator)Director, Center on the Ecology of Early Development, Boston University