One of the five major groups of lipoprotein
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Editor's Summary by Linda Brubaker, MD, and Christopher C. Muth, MD, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from July 25-31, 2026.
Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?
Nature or nurture—which is more important when it comes to health conditions?Would I benefit from taking nattokinase along with my statin?Mechanism of action of nattokinase vs. statin medications on coronary artery health
Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.
T3 + Vitamin A = LDL + Pregnenolone = All Sex Steroid Hormones The Critical Biochemical Pathway Most People Never Learn About In this episode of the Improvement Warrior Podcast (Substack, Apple), Jason Yun breaks down a critical biochemical pathway: how T3 (the active form of thyroid hormone) works with Vitamin A to help utilize LDL cholesterol, which then supports the production of pregnenolone — the precursor to all sex steroid hormones (testosterone, estrogen, progesterone, etc.). Jason explains the interconnected roles of these molecules in energy production, hormone balance, fertility, mood, and overall vitality. He connects this pathway to his core teachings on circadian biology, mitochondrial health, and the importance of proper light exposure. The discussion highlights why disruptions in this chain are common in modern life and offers practical insights into supporting it naturally through lifestyle, nutrition, and environment. Whether you're dealing with low energy, hormonal imbalances, or simply want to understand how your body produces and regulates sex steroids at the deepest level, this episode delivers clear, actionable knowledge rooted in real biology rather than conventional approaches.Timestamp Log 0:00 – Intro & welcome to Episode 891:10 – Overview of the key pathway: T3 + Vitamin A3:45 – Role of LDL Cholesterol in the process6:20 – Pregnenolone as the mother hormone9:00 – How this leads to all sex steroid hormones11:30 – Practical implications for energy, hormones & vitality13:45 – Ties to circadian biology, light exposure, and mitochondria15:30 – Key takeaways and action steps16:40 – Closing thoughts & outroResources MentionedImprovement Warrior Newsletter PatreonSubstackOne Tap ZapMagnesium Breakthrough
What actually works? This episode features audio from: How to Lower Cholesterol with the Portfolio Diet Are Plant Sterols Effective for Lowering Cholesterol? The Best Source and Dose of Plant Sterols for Lowering Cholesterol Visit the video pages for all sources and doctor’s notes related to this podcast.
More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach?
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
When it comes to ideal LDL cholesterol levels in the blood, ideal is a bit of a moving target. Johns Hopkins cardiologist Roger Blumenthal, chair of an American College of Cardiology committee that has just updated cholesterol guidelines, says it … What LDL cholesterol level should you be aiming for? Elizabeth Tracey reports Read More »
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Even half an egg a day increases mortality. Replacing red meat with soy, nuts, or plants slashes risk of death and disease. #CholesterolTruth #EggRisk #HealthyProtein
On my 48th birthday, my mom reminded me that my grandmother died of a heart attack at the same age. That conversation sent me to review my cholesterol results... and changed what I put on my plate (a little bit). I already eat a plant-based diet, exercise regularly, and don't smoke. But new guidelines from the American College of Cardiologists have shifted the target for LDL cholesterol from 130 down to under 100 mg/dL. At 102 (in May 2025), I had work to do. So I made some small, deliberate additions to my diet. No meds, no overhaul, no yucky supplements! A retest just last week showed promising results. Here's what happened. ➡️ Join us to discuss Dr. Greger's Lower LDL Cholesterol Naturally with Food book: Kick-off event on June 25th (free): https://brigittegemme.com/lower-ldl-kick-off/
Je hebt te horen gekregen dat je cholesterol te hoog is. Maar wat betekent dat eigenlijk? En is een hoog cholesterol automatisch gevaarlijk?In deze aflevering spreek ik met Remko Kuipers, cardioloog en onderzoeker. Remko combineert zijn achtergrond in de farmacie met een evolutionaire kijk op gezondheid en zet zich in voor preventieve cardiologie.We bespreken:Wat cholesterol eigenlijk is en waarom je het niet kunt missenWaarom LDL niet het slechte cholesterol isWat HDL en triglyceriden je vertellen over je cardiovasculaire risicoHoe je lipidenprofiel verandert als je koolhydraatarm eetWanneer statines zinvol zijn, en wanneer nietWaarom voeding (te) weinig aandacht krijgt binnen de reguliere cardiologieMeer info over Remko Kuipers https://remkokuipers.com-----------De supplementen van Bonusan ook proberen? Krijg nu 10% korting met de code TNS10 via https://www.bonusan.com/nl-NL-----------
A case study where a second opinion is necessaryWhat are your thoughts on the recent news implicating niacin in cardiovascular disease?
Gary Taubes on Rethinking Diabetes: Diet, Insulin, and the History Behind Low-Carb Treatment: Journalist Gary Taubes is author of “Rethinking Diabetes: What Science Reveals About Diet, Insulin, and Successful Treatments.” The book traces diabetes treatment history and argues that carbohydrate restriction was standard care from 1797 through the early 20th century until insulin therapy shifted practice toward drug-centered management and higher-carbohydrate diets. Taubes explains how insulin's discovery changed dietary priorities, how later technology (radioimmunoassay) revealed that most diabetes is type 2 with insulin resistance and high insulin rather than deficiency, and why giving more insulin can worsen weight gain. They discuss major trials (including ACCORD, ADVANCE, and Look AHEAD) that failed to show benefits from intensive drug-based glucose control, the influence of low-fat guidelines, Richard Bernstein's role in blood-glucose self-monitoring and low-carb control, controversies about obesity models, ketosis vs ketoacidosis, GLP-1 drugs, and LDL increases on ketogenic diets.
Join commit to 6 here01:20 The Satiety Debate: Apples vs. MCT Oil12:52 Understanding LDL Cholesterol and Misinformation18:03 The Impact of Misinformation on Women's Health27:18 Conclusion and Call to Action
Is oatmeal healthy?I have a higher-than-normal carotid artery intima-media thickness and no appreciable plaque. Should I be concerned?Should my husband and I take the hepatitis B vaccine?
This detailed discussion unpacks the complexities of LDL cholesterol, its measurement, and its actual impact on health, challenging common misconceptions and guidelines.Chapters00:00 The Role of LDL in Cardiovascular Health03:56 Population Studies: Cholesterol and Mortality11:58 Cholesterol Guidelines: A Critical Review21:17 Questioning LDL Measurements and Accuracy
I'm confused by information presented on diets containing meat as being dangerous. Could you shed some light?Assisted living models that would be of benefit to older adults
Expect a renewed push to take a statin at your next doctor's visit; PREVENT online calculator skews decisions to prescribe cholesterol reduction as early as 30; American Heart Association discourages at-risk patients from taking fish oil and garlic supplements—REALLY? Renewed interest in muscle as promoter of overall health and metabolism; The key role of urolithin A (Mitopure®️) for supporting muscle function. Is DHEA a reasonable supplement for post-menopausal women?
Would strontium help in the healing of lumbar fractures? How about as a preventive?How valuable is the hs-CRP test? Are there any drawbacks to eating canned fish?What are your thoughts on Arterosil for cardiovascular health?
The benefits of saunaThe Take Back Your Health TourA follow-up on milk thistle interactions with drugsWhat are your thoughts on low-dose saw palmetto for hair growth?Is monk fruit a safe sweetener to use?
What are your thoughts on peptides?So it's not possible to get enough protein from plants only?What about the downsides to animal protein?Are there any negative reports on the usage of extra virgin olive oil?Is it true that the nutritional value of farmed seafood is the same as wild caught?
Highlights from Dr. Hoffman's New Zealand bike tripDo you prefer whey protein isolate or concentrate?My liver enzymes went up taking a statin drug. My doctor recommends I take milk thistle. What are your thoughts?If any supplement protocols are out of stock, should we make substitutions?
Leyla Muedin, a registered dietician nutritionist, shifts the discussion beyond cholesterol and statins to “hidden” cardiovascular risks from insufficient vitamin K and folate intake. Citing Cleveland Clinic and other research, she notes a high prevalence of vitamin K deficiency in the U.S. and widespread inadequate folate intake globally, including low folate levels among women of reproductive age. She explains that vitamin K2 may help inhibit arterial and soft-tissue calcification via activation of matrix GLA protein, with studies linking higher K2 (MK-7) intake to lower coronary heart disease risk and slowed coronary artery calcification. Folate supports vascular function through homocysteine metabolism, with evidence associating higher folate intake with lower cardiovascular mortality, emphasizing active 5-MTHF over folic acid due to conversion limitations in many people. She also notes statins can downregulate vitamin K metabolism and encourages discussing risks, benefits, and supplements with a doctor.
Heart disease should be treated just like cancer, says guest Mike McConnell, an author and expert in preventive cardiology at Stanford: Detect and stage early, then treat aggressively. In his practice, McConnell focuses on using low-dose CT imaging for detecting early coronary artery disease. He also helped pioneer the use of AI to infer cardiovascular risk from retinal scans. Such non-invasive, consumer-friendly tools could expand prevention, personalize therapy, and cut heart attacks and strokes across the board, he says. “Everybody also deserves a proactive preventive cardiologist in their phone,” McConnell tells host Russ Altman of the latest approaches to heart disease on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Michael V. McConnell, MD, MSEE Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Michael McConnell, a professor of cardiology at Stanford University. (00:03:02) Reframing Heart Disease Why coronary disease should be approached the same as cancer. (00:05:46) Core Risk Factors The key drivers of cardiovascular disease, and life's essential eight. (00:07:18) Coronary Artery Calcium Scoring How low-dose CT scanning detects disease before symptoms develop. (00:08:57) The Limits of Stress Testing Why traditional stress tests often miss early coronary disease. (00:10:18) AI in Cardiac Imaging Using AI to identify hidden risks in routine chest scans. (00:11:30) Retinal Imaging How AI analysis of retinal blood vessels can predict heart disease risk. (00:14:55) Detecting Risk Before Symptoms Why retinal and vascular changes occur long before clinical signs appear. (00:15:58) Staging Coronary Disease Using calcium scores to stage coronary disease and personalize treatment. (00:19:36) Direct-to-Consumer Prevention The rise of mobile health records, wearable devices, and AI tools. (00:22:23) Opportunities & System Challenges Balancing accessibility, guideline-based care, and healthcare system capacity. (00:25:26) AI-Powered Health Record Analysis The potential of automated reviews to identify silent risk factors. (00:27:41) Physician Adoption & System Friction Barriers to integrating early detection tools into clinical practice. (00:30:12) Advances in Treatment Overview of current cholesterol therapies and plaque stabilization. (00:33:31) Future In a Minute Rapid-fire Q&A: prevention, implementation science, and future hopes. (00:35:38) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Understanding and Managing Heart Health: In this Heart Health Month episode of the Intelligent Medicine Podcast, nutritionist Leyla Muedin addresses a listener's question about elevated cholesterol levels and calcium scores. Drawing on an article written by Dr. Hoffman, she emphasizes the importance of discussing statin use with a doctor, considering individual risk factors, and getting additional tests like VAPs, NMR, homocysteine, and lipoprotein levels. The episode explores the importance of vitamins K2 and folate in cardiovascular health, addressing nutritional deficiencies, and the impact of dietary choices on heart health.
In this episode, I sit down with neuroscientist Dr. Louisa Nicola to unpack what women actually need to know about Alzheimer's risk, cognitive decline, and long term brain protection. We break down APOE genetics, advanced blood biomarkers that can now detect amyloid and tau with remarkable accuracy, and why brain health is inseparable from metabolic health. Louisa explains how muscle acts as a metabolic sink for glucose, why resistance training and high intensity intervals stimulate BDNF, and how sleep drives the glymphatic system to clear amyloid from the brain. If you want practical tools to assess your personal risk, understand your labs, and build a proactive prevention plan decades before symptoms appear, this conversation is for you. → Leave Us A Voice Message! Topics Discussed: → What does APOE4 mean for Alzheimer's risk? → Can exercise prevent cognitive decline? → Do blood tests detect early Alzheimer's? → How does perimenopause affect brain health? → Does hormone therapy reduce dementia risk? Sponsored By: → Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/KELLY and save up to 39% off your Mitopure® Gummies. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → Cozy Earth | Head to https://cozyearth.com and use code BEWELL for up to 20% off. And if you get a post-purchase survey, make sure you tell them you heard about Cozy Earth right here at the Be Well by Kelly podcast. → LMNT | Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/Kelly. Find your favorite LMNT flavor, or share with a friend. Timestamps: → 00:00:00 - Introduction → 00:01:27 - Mission to end Alzheimer's → 00:03:28 - Women's rate of Alzheimer's → 00:04:11 - Alzheimer's overview → 00:07:44 - Education level & health → 00:09:57 - Anatomy → 00:14:16 - Neuroplasticity & glucose → 00:19:38 - Amyloid-beta → 00:26:41 - LDL Cholesterol → 00:28:36 - Preparing for menopause → 00:31:30 - Blood testing recommendations → 00:34:26 - Lifestyle interventions → 00:39:05 - Nutrition & the MIND diet → 00:42:19 - Zone 2 vs zone 5 training → 00:44:36 - Lactic acid → 00:47:58 - HRT is protective → 00:50:19 - When to test for HRT → 00:51:56 - Testosterone + brain health → 00:53:40 - Cognitive reserve → 00:57:12 - Hot flashes → 00:58:13 - Quick fixes → 01:00:01 - Brain surgery → 01:05:38 - The brain code Show Links: → Function | Own your health for $365 a year. That's a dollar a day. Learn more and join using my link. Visit https://www.functionhealth.com/bewellbykelly and use gift code BEWELL25 for a $25 credit toward your membership Further Listening: → How to Take Control of Your Health in a Toxic Food Landscape | Max Lugavere Check Out Louisa: → Instagram → The Brain Code Check Out Kelly: → Instagram → Youtube → Facebook
HEALTH NEWS A Simple Diet Change Could Slow Liver Cancer Brief, intensive exercise helps patients with panic disorder more than standard care Lucid dreaming could be used for mental health therapy, new study says US cancer institute studying ivermectin's ‘ability to kill cancer cells Too many saturated fats may be more harmful than too many refined carbohydrates. Clips Andrew Bridgen - https://x.com/ABridgen/status/2020573528571977993?s=20 MAHA Alliance Mike Tyson Super Bowl Commercial - https://www.youtube.com/watch?v=jg1SjFt1a_U KETO DIET RISKS The rationale for Keto Diet by its advocates Restricting carbohydrates, suppressing insulin and ketosis will lead to better metabolic heath, increase weight loss, reduce inflammation, and protect from chronic diseases. Keto Claim: Carbohydrates raise insulin leading to fat storage – keto lowers insulin and burns body fat better Debunking: Ketosis is a metabolic state and not a health outcome. For example ketones can be elevated by very long fasting, starvation, different illnesses and uncontrolled diabetes. Keto Claim: By minimizing carbs keto stabilizes blood sugar, reduce insulin spikes, and improve insulin sensitivity that benefits those with type 2 diabetes Debunked: This claim contradicts the evidence of induced hepatic insulin resistance and glucose intolerance in longer-term studies. In animal models, keto diets impair blood sugar regulation within several days, which shows harm for metabolic health. Keto Claim: Ketones are seen as “clean” fuel that advocates claim are anti inflammatory and neuroprotective. Believe that this along with ketosis lowers triglycerides, raises HDL cholesterol, and improves lipid profiles. They argue that the increase in LDL cholesterol is benign. Claim saturated fats are harmless if carbs are low Debunked: This claim is undermined by the increased LDL cholesterol, triglycerides, and cardiovascular risks from saturated fats in animal products. Meta-analyses show no long-term lipid improvements from keto diets. Rather this is the risk in elevated low-density lipoprotein and very-low-density lipoproteins that increase cardiovascular disease Also, insulin reduction does not override the quality of fat. LDL cholesterol and ApoB, as well as atherosclerosis, increase significantly on an animal based diet. Saturated fat still remains a causal factor for cardiovascular disease. Keto Claim: High protein and fat increases satiety and therefore reduces hunger Debunking: Weight loss is primarily from reduced intake due to satiety, not fat-burning efficiency. Long-term keto adherence often leads to weight regain with no significant sustained benefits for visceral fat or appetite control. hort term weight loss is not same as long term benefits. A study shows that weight loss at 3-6 months on a keto diet disappears by 12 months Keto Claim: It enhances brain function and energy that then improves mental clarity and mood. Argue that animal products like eggs and organ meats provides choline and other nutrients for brain health. Debunked: There is no strong evidence for this claim. In fact keto's nutrient deficiencies and lack of fiber in the long term can lead to fatigue, constipation and in women neural tubal defects. Keto's claims are only based on short term trials. Keto Claim: Use the evolutionary argument that humans evolved eating meat and fat – same argument the paleo folks used. Therefore, they believe keto diets align with human biology Debunked: A big study in Science in 2025 analyzed tooth enamel from skeletons of some of our oldest human ancestors, 3.5 million years ago, and found they ate predominately a plant based diet with no substantial sigh of mammalian meat. The isotopes matched herbivores (fruits, leaves and grasses, tubers, nuts, other vegetation) not carnivores. Keto Diet Risks It is worth noting, according to the Northwestern University Health site, there is a sizable drop out rate of participants in keto trials. Although, there are studies that show keto does what it claims in the short term, there are no long-term human data to support their claims that an animal-based diet does this efficiently. Important, research leans in the direction to indicate that keto's benefits – especially weight loss and glucose reduction, are transient and may not be directly related to animal food consumption itself but rather to calorie reduction and limiting glycogen. Long term prospective studies and systematic meta analysis evaluations consistently show high red meat consumption, full-fat dairy and animal fats are associated with the following medical conditions. This is true even when carbohydrate intake is low A good thorough study in JAMA shows that unprocessed red meat mildly increases all cause mortality – about 3-5% per 100 grams meat per day High red and processed meat consumption increases carcinogenic N-nitroso compounds and heterocyclic amines that raise cancer risks by up to 18% per 50-100 grams/day – from meta analysis in the European Journal of Epidemiology Dairy increases IGF-1 levels thereby too much calcium also suppressing Vitamin D and elevating prostate cancer risks by 79% per 400 gram dairy per day. Worse for processed meats that inreases risk by 21% per 20 grams/day – American Journal of Epidemiology Red meat is linked to hormonal disruptions and carcinogens contributing breast cancer – European Journal of Cancer Total unprocessed red meat consumption shows a modest 5% risk in pancreatic cancer per 100 grams/day. – From journal Clinical Nutrition Many meta-analyses on meats have a relationship to stomach/gastric cancer, but processed meats are worse than unprocessed red meat. From study in Nutrients – 24 studies showed unprocessed red meat associated with gastric cancer by about 25% increase risk for every 100 grams/day. Unprocessed red meat is linked to an 11% higher risk in overall cardiovascular disease risk due to inflammation and endothelial dysfunction. – from European Heart Journal Saturated fats in meats increases non-HDL cholesterol and blood pressure and raises the risks of ischemic heart disease by 119% per 100 grams/day red meat – from American J Clinical Nutrition Red meat diets reduce LDL Cholesterol much less than plant proteins and thereby increase atherosclerosis risks – from the journal Circulation Red meats (an processed meats also in this study) contributes to insulin resistance via heme iron and raises Type 2 diabetes risks by up to 51% per 50 grams/day – International Journal Environmental Research in Public Health Saturated fats in unprocessed red meat has a modest positive 12% increase with stroke risk – From European Heart Journal Unprocessed poultry consumption shows a modest 4% increase in incident cardiovascular events per 100 grams/day. This is believed to be due to arachidonic acid poultry – in JAMA Red meat contributes to sodium and saturated fat intact raising hypertension conditions by 14% per 50-100 gram/day – from journal Advanced Nutrition Saturated fats from animal products cause lipotoxicity and insulin resistance, that promotes hepatic fat accumulation leading to non-alcoholic fatty liver disease – from Cardiovascular Development and Disease High animal protein increases urinary calcium and acid overload leading to the formation of kidney stones – from the journal Nutrient Animal-heavy diets have low fiber and micronutrient intake that contribute to nutrient deficiencies. Also causes constipation that can lead to immune system issues. – from the journal Nutrients Red meat, dairy, and eggs disrupts the gut metabolism of carnitine and choline. This promotes TMAO plaque formation and inflammation that leads to atherosclerosis. – from Journal of Cardiovascular Development. Although unprocessed meat consumption has not been adequately associated with dementia and Alzheimer's – yes, processed meats do – there are studies showing red meat is associated with “subjective cognitive decline” (SCD) which is related to precursors to dementia and Alzheimer's. A study in journal Neurology links unprocessed red meat eaten at 1 or more servings per day to 16% higher risk in SCD. High caloric density from saturated animal fats displaces fiber that contributes to weight gain obesity. From Neal Barnard in the American Journal of Clinical Nutrition Animal products transmit prions that are associated with neurodegenerative disorders. Proinflammatory compounds like TMAO are linked to neurological risks. – in International Journal of Molecular Science
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Nathan Price, Professor and Co-Director at the Buck Institute for Research on Aging. Together, they explore how systems biology, artificial intelligence, and deep health data are changing the way we approach aging and prevention. Nathan explains why looking at single biomarkers falls short and why a network view of biology gives a clearer path to understanding disease and resilience.Nathan shares how new tools, like genetics, proteomics, and the emerging field of digital twins, can help predict disease risk years in advance and guide more effective, personalized interventions. He also discusses how integrating data from wearables, blood tests, and the microbiome can help people move from reactive medicine to proactive health decisions, allowing for interventions that fit the individual.The conversation highlights the promise and practical limits of current technologies, the trade-offs involved in optimizing health, and the power of AI to accelerate both research and personal health journeys. Nathan makes a strong case for the unique biology each person brings to the table and shows how the tools available today can help anyone take charge of their own healthspan in ways not possible before.Guest-at-a-Glance
Dr. Mary Newport shares groundbreaking research analyzing cholesterol profiles across 40 years of studies, challenging conventional wisdom about saturated fat and heart health. We discuss her findings on MCT oil for brain health, the 288 caregiver reports showing cognitive improvements, and practical protocols for using coconut oil and ketones.Dr. Mary Newport, physician and Alzheimer's researcher, joins us to discuss her latest research that challenges decades of assumptions about coconut oil and saturated fat. In this interview, we explore: • Her comprehensive analysis of 26 studies spanning 40 years (984 lipid profiles) showing coconut oil's unexpected effects on cholesterol • The 288 caregiver reports documenting improvements in memory, cognition, and daily function • How medium-chain triglycerides (MCTs) may provide an alternative fuel source for aging brains • Practical protocols for incorporating coconut oil and MCT oil into your diet • The controversial history of dietary fat guidelines and the trans fat problem • Why the medical establishment has been slow to acknowledge ketone research Dr. Newport's work began with her husband Steve's dramatic response to coconut oil after his early-onset Alzheimer's diagnosis. Her research has since expanded to include hundreds of case reports and comprehensive lipid analysis.
On today's Good Day Health Show - ON DEMAND…Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken begin with an oncology report on cancer survival rates with a rise in success in treating, including a 5-year survival rate for all cancers, and another gain in GLP-1s use as it attributes to cardiovascular health. Next up, Doug and Dr. Ken address cholesterol levels and why simply looking at the number alone isn't beneficial because it's only one part of an overall health assessment, and why cardiologists are no longer focusing on “good cholesterol.” There's also a protein 20% of people have that causes those who look like they are the most fit and wind up with an early heart attack because of this elevated protein, and how it correlates to LDL cholesterol. Lastly, Doug and Dr. Ken answer listener questions, including one about exercise and depression. A new report aggregated from numerous studies suggests exercise is just as effective as psychological therapy or antidepressants for alleviating symptoms of depression. This further's the “exercise is medicine” movement as it relates to mild to moderate depression. Additionally, the new food pyramid stresses protein, it stresses getting rid of processed food, it stresses getting rid of added sugar (natural sugars are OK), and minimization of saturated fat in patients moderate to high risk patients with circulation issues. Website: GoodDayHealthrShow.com Social Media: @GoodDayNetworks
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Dr. Williams and Dr. Kahn explore how ketogenic diets and saturated fats impact cardiovascular health and longevity. #KetogenicDiet #SaturatedFat #HeartHealth
The Real Truth About Health Free 17 Day Live Online Conference Podcast
To prevent America's top killer, we must reduce sodium, sugar, saturated fat, cholesterol, and foods that harm the microbiome. #HeartDiseasePrevention #DietMatters #Nutrition
Could you discuss GABA for insomnia and sleep support? Are there long-term health benefits?What impact does a cocktail of pharmaceutical drugs have on the microbiome?Can I take more than 2 daily doses of Dr. Ohira's probiotics?Which is the correct estrogen to take in HRT? Estriol or estradiol?In light of the recent EPA proposal to double permissible formaldehyde emissions, how does this jibe with MAHA?
Top stories of 2025Does the use of statins lead to muscle loss?I have mitral valve prolapse with regurgitation. Should I increase my supplement dosages?
For dark days, get some sun in your eyesThe misleading vegan diet twin studyA least favorite thing from one of our listeners
What are your thoughts on the efficacy of strontium for bone health?What to you think of HRT for bone health?I have aortic valve stenosis. Is there any alternative to surgery?I have dry eyes after cataract surgeryAre there any benefits to Deer Antler for increasing HGH?
The Benefits of Matcha for Women in Menopause: Nutritionist Leyla Muedin discusses the potential benefits of matcha for women going through menopause. She explains how matcha, a finely ground green tea powder, offers higher concentrations of antioxidants, amino acids, and phytonutrients compared to regular green tea. These properties can help support cognitive function, mood stabilization, cardiovascular health, and weight management. The episode also touches on the importance of maintaining a healthy lifestyle, emphasizing an anti-inflammatory diet, regular exercise, restful sleep, and meaningful social connections. Leyla highlights how simple daily rituals, such as enjoying a cup of matcha, can provide emotional grounding and routine for women navigating menopause.
Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.
"Organic produce isn't necessarily not sprayed with pesticides. There's different types of pesticides. They just aren't allowed to use synthetic pesticides. Sometimes they can be even more toxic. Sometimes they have to use larger amounts because they're less effective especially given the cost difference between organic and non-organic, I don't see that it's really warranted for something" - Dr. Matthew Nagra Many people still believe that what they eat, how they live, their experiences, and even who they share their life with has no impact on their physical health. Today's guest is out to dispel that. Dr. Matthew Nagra is a Naturopathic Physician, and in case you're wondering if a Naturopathic Physician is a real doctor, Dr. Matthew Nagra is a health practitioner who treats people holistically. He follows a scientific and evidence-based approach to treating ailments. Dr. Matthew Nagra practices Integrated Health in Vancouver, BC. He has a BSc in Microbiology from the University of Victoria and completed his ND training at the Boucher Institute. He has been vegan for over 10 years, is certified in plant-based nutrition through the T. Colin Campbell Center for Nutrition Studies. He regularly shares information regarding nutrition and health across his social media pages. Learn how to live healthier as you listen to this episode with Dr. Matthew Nagra. What we discuss in this episode: First things first, Dotsie shares 3 things she learned from her book-writing retreat What does a Naturopathic Doctor look for when a patient comes for evaluation compared to what a traditional doctor does? The impact of the food you eat, especially dairy products, when you have asthma Dr. Matthew Nagra talks about what he learned from the nutrition debates in school and the studies on saturated fat, LDL, collagen, etc. Refined sugar vs. fruits – What to do when sugar cravings hit What does raw veganism mean, and how does it relate to a healthy diet? With book recommendation - Becoming Raw: The Essential Guide to Raw Vegan Diets, and Becoming Vegan, both by Brenda Davis Do you know the massive difference between butter and olive oil? How much sodium does your body need if you are healthy? What you need to know about organic food, non-organic food, and GMO The upside and downside of eating eggs and plant-based sources of choline Watch Dr. Matthew Nagra's debates with carnivores: Vegan vs. Carnivore Debate: Saturated Fat and LDL-Cholesterol and Debating LDL-Cholesterol, Saturated Fat, and CVD with a Carnivore Connect with Dr. Matthew Nagra: Website - https://drmatthewnagra.com/ Instagram - https://www.instagram.com/dr.matthewnagra/ Facebook - https://web.facebook.com/dr.matthewnagra/ Twitter - https://twitter.com/drmatthewnagra Click the link below to support the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Send us a voice message and ask a question. We want to hear from you! Switch4Good.org/podcast Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★ https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good
How do I keep my LDL low enough without compromising my brain and my liver?I read that fish oil can raise LDL cholesterol. Is this true?A questionable case study on pycnogenol
Reasons for nausea My PSA was 4.0 six months ago, and now it's up to 4.55. What should I do?I have lupus and need to take Methotrexate. How can I protect my liver and immune system?The important relationship between vitamin D3 and K2
Heart disease is still the number one killer in the U.S.—but are we even looking at the right markers to prevent it? In this eye-opening episode, Shana sits down with Dr. Urban Kiernan, founder and CEO of iMetabolic Biopharma Corporation, to break down what your lipid panel actually means, why total cholesterol and LDL often distract from the real risks, and how insulin resistance plays a central role in heart disease—especially during menopause. Dr. Kiernan shares how his biotech company is leveraging AI, protein therapy, and root-cause science to transform how we prevent and treat metabolic disease—and why most conventional approaches miss the mark entirely. If you've ever been confused by your labs, put on statins without a full explanation, or wondered why we're still seeing record rates of heart attacks and strokes, this conversation will bring clarity and direction.
Maximizing Fitness, Fat Loss & Running Through Perimenopause
Lady runners and endurance athletes, don't let anyone ever tell you we can't lower our cholesterol, balance our hormones, and boost our running performance without extreme diets, endless supplements or prescriptions. Most of the time, there is a (much) better way and it's time we learn some specifics, nuances, and targeted female-specific strategies to try!In this episode of Maximizing Hormones, Physique, and Running Through Perimenopause, Louise Valentine, one of the world's leading health, fitness and performance experts, shares a simple, science-backed roadmap for avid active women and recreational runners age 35+ who are navigating perimenopause and beyond.Louise reveals root cause mechanisms of why LDL cholesterol often spikes as estrogen declines and how outdated advice about cutting out eggs or red meat isn't the full picture. Drawing from over two decades of coaching and research, her own fiercely inspiring health journey, and empowering thousands of individuals over the course of her proven career designing integrative health and fitness interventions, she explains practical steps you can take to improve biomarkers in as little as three months.You'll learn which supplements actually make a difference, how much your specific food choices matter, awareness of how seed oils sneak into your pantry, and why advocating for yourself with doctors matters. You'll get a step-by-step playbook to discuss your labs with your doctor to be fully heard and get the comprehensive effective care you deserve. Most importantly, you'll discover realistic strategies, rooted in cutting-edge female-specific science, that help you feel energized, resilient, and confident in your body.If you're a driven, active woman who's tired of feeling blindsided by midlife changes, this episode is your playbook for thriving with less stress, relentless confidence, and more strength.Link to our FullScript where you can see our curated best supplement picks under "Favorites" & save 20% off the supplements mentioned in today's episode: https://us.fullscript.com/welcome/breakingthroughwellness/store-startLearn & level up with my free nutrition guide and award-winning Badass Breakthrough Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Our affiliate link to check Function Health for comprehensive blood work: https://my.functionhealth.com/signup?code=LVALENTINE11&_saasquatch=LVALENTINE11 Take advantage of our podcast listener discount and save 20% off all of Kion's science-backed clean products: https://www.getkion.com/pages/maximizing Promo code “LOUISE” saves on all future orders!Episode Highlights:(0:000 Intro(3:04) A step-by-step roadmap to lower LDL(7:41) The importance of advanced lipid testing(11:13) A client's success challenging the “only meds” advice(14:56) Louise's personal results lowering biomarkers(19:26) Fueling frameworks that boost natural hormone production(22:42) OuTune in weekly to "Maximizing Hormones, Physique, and Running Through Perimenopause" for our simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect!Instagram
In this episode of The Jordan Syatt Podcast I speak with the incredible Dr. Danielle Belardo (IG: @daniellebelardomd) about:- The Best Diet for Heart Health- The Truth About LDL Cholesterol- How to Lower Your Blood Pressure- Tirzepatide and GLP-1's for Weight Loss- Menopause Misinformation- How Much Muscle Do You Actually Need for Health?- The Most Important Health Habits for Longevity- And more...I hope you enjoy this episode and, if you do, please leave a review on iTunes or Spotify (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all here: https://www.sfinnercircle.com/
Send us a textOverview and alternative interpretation to the mainstream view on how dietary fat and cholesterol relate to cardiovascular disease.Episode Summary: Tucker Goodrich is an engineer by training who has become a prominent independent researcher and blogger on nutrition and metabolic health, focusing on the harms of seed oils and polyunsaturated fats.About the guest: Nick Jikomes and Tucker Goodrich explore atherosclerosis and heart disease, critiquing the standard model that blames high LDL cholesterol while highlighting how oxidized LDL—driven by dietary linoleic acid from seed oils—plays a key role in plaque formation and inflammation; they discuss historical shifts in heart disease rates, genetic factors like familial hypercholesterolemia, the limitations of animal studies, and why reducing seed oil intake could prevent issues more effectively than just lowering cholesterol.Discussion Points:Atherosclerosis involves plaque buildup in arteries, often leading to heart attacks, but plaques contain oxidized fats and cholesterol, not just native cholesterol.Dietary cholesterol has little impact on blood levels or heart disease in humans, unlike in rabbits used in many studies.High LDL may not be inherently bad; oxidized LDL from polyunsaturated fatty acids (PUFAs) like linoleic acid causes macrophages to overeat and form harmful foam cells.Familial hypercholesterolemia patients only show higher heart disease rates in modern, industrial diets high in seed oils, not historically.Populations like the Kitavans and Tsimané have high apoB but no heart disease on traditional diets low in industrial foods.Fried foods are oxidized seed oils, explaining why they're unhealthy despite omega-6 fats being labeled "heart-healthy."Omega-3 fats can displace omega-6 in cells, reducing oxidation risk.Reference Papers:Witztum & Steinberg (1991)Boren et al. (2022)Related episode:Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
Dr. Sarah Myhill has worked full time in National Health Service and independent medical practice. She has a special interest in Chronic Fatigue Syndrome and ME. Show sponsors: Quicksilver Scientific - 15% off your first order by using the code "ultimatehealth15" at checkout Troscriptions - 10% off your first order by using the code "JESSE" at checkout Show notes: https://jessechappus.com/657
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3012: Dr. Neal breaks down the role of genetics in cholesterol levels and explains how even those with a family history of heart disease can benefit from targeted lifestyle changes. From diet tweaks to exercise strategies, his practical tips empower listeners to take control of their heart health, no matter their DNA. Quotes to ponder: "HDL actually helps the body clear LDL from the arteries, which is why it's good." "One of the most effective ways to lower blood cholesterol and blood pressure quickly is weight loss." "Fiber is so helpful because it helps bind to cholesterol and helps the body get rid of it." Episode references: Omega-3 Fatty Acids (NIH Office of Dietary Supplements): https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer USDA FoodData Central: https://fdc.nal.usda.gov/ National Heart, Lung, and Blood Institute: https://www.nhlbi.nih.gov Learn more about your ad choices. Visit megaphone.fm/adchoices
The truth behind a controversial keto diet study that's been making headlines is exposed. What was hailed as groundbreaking science is now unraveling under scrutiny. Dr. Roxie Becker dives into the study's deeply flawed data, misleading conclusions, and the dangerous falsehoods being spread about keto's health effects when she joins “The Weight Loss Champion” Chuck Carroll on The Exam Room Podcast. With decades of science and data on their side, Chuck and Dr. Becker separate fact from fiction to protect public health. Don't miss this eye-opening conversation that challenges what you thought you knew about keto. Truth matters. And the truth is that having high LDL cholesterol increases your risk of heart attack, stroke, and cardiovascular disease despite what the study reported. — — SHOW LINKS — — Watch This Episode https://www.youtube.com/watch?v=g13xNeExCgo — — — Original Study https://www.sciencedirect.com/science/article/pii/S2772963X25001036 — — — Response https://osf.io/preprints/osf/78bph_v1 — — EVENTS — — Exam Room LIVE: Longevity and Muscle Building GreenFare Organic Restaurant Where: Herndon, VA When: May 28, 2025 Tix: https://bit.ly/ERTixGFMay2025 — — — International Conference on Nutrition in Medicine Where: Washington, DC When: August 14-16, 2025 Tix: https://www.pcrm.org/icnm — — BECOME AN EXAM ROOM VIP — — Sign up: https://www.pcrm.org/examroomvip — — THIS IS US — — The Exam Room Podcast Instagram: https://www.instagram.com/theexamroompodcast — — — Chuck Carroll Instagram: https://www.instagram.com/ChuckCarrollWLC Facebook: https://www.facebook.com/ChuckCarrollWLC X: https://www.twitter.com/ChuckCarrollWLC — — — Physicians Committee Instagram: https://www.instagram.com/physicianscommittee Facebook: https://www.facebook.com/PCRM.org X: https://www.twitter.com/pcrm YouTube: https://www.youtube.com/user/PCRM Jobs: https://www.pcrm.org/careers — — SUBSCRIBE & SHARE — — 5-Star Success: Share Your Story Apple: https://apple.co/2JXBkpy Spotify: https://spoti.fi/2pMLoY3 Please subscribe and give the show a 5-star rating on Apple Podcasts, Spotify, or many other podcast providers. Don't forget to share it with a friend for inspiration!
Let's break down key insights from a recent two-hour and 20-minute conversation between Dr. Peter Attia and renowned lipidologist Tom Dayspring. Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: https://bit.ly/berberine-fasting-accelerator Use code podcast to save 12% Get the Blood Work Cheat Sheet: https://courses.highintensityhealth.com/blood-work-cheat-sheet Show Notes: https://bit.ly/4hrDc72 Time Stamps: 0:00 Intro 0:52 Cholesterol's Role in Atherosclerosis 1:51 Triglycerides & Insulin Resistance: The Overlooked Risk Markers 3:28 Lipoprotein Exchange & Insulin Resistance 7:18 Triglycerides to HDL Ratio as a Risk Indicator 8:36 Metabolically Healthy Phenotype & LDL: 9:20 Sauna Therapy for Cardiovascular Health: 11:00 Cholesterol, Endothelial Health & Plaque Formation: 14:53 Case Study: A 24-Year-Old Athlete with High LDL 21:00 Lipoprotein(a) (LP(a)) and Its Role in Cardiovascular Risk: