POPULARITY
Max Levchin (@mlevchin) is a serial entrepreneur and investor in 100+ startups. He's the founder and CEO of Affirm, the payment network powering consumer purchases and merchant growth. An original PayPal co-founder, Max served as CTO until its 2002 acquisition by eBay.This episode is brought to you by:ProLon: science-backed Fasting Mimicking Diet that helps activate cellular renewal through fasting, while still eating nourishing meals: ProlonLife.com/TimMonarch track, budget, plan, and do more with your money: Monarch.com/Tim Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: Shopify.com/timTimestamps:[00:00:00] Start.[00:02:50] The Ronin line that rewired how Max makes every decision.[00:06:09] Paprika-style brain-computer interfaces.[00:09:09] PayPal's founders lived inside a Neal Stephenson novel.[00:19:21] Transformation via Neuromancer and Snow Crash.[00:23:40] The book that found Max his wife.[00:29:24] The real secret to a great marriage.[00:38:29] What's worth tracking, and what's not.[00:44:13] A scrawny kid, a clarinet, and a Kyiv velodrome.[00:46:55] What going all-out on a bike actually gives you.[00:51:02] The mantra by which Max rides.[00:53:02] A Soviet kid's fear of socialism.[01:02:48] Making a profit without destroying society.[01:04:31] What is Affirm, and why did every banker say it would fail?[01:20:18] Why the best mathematicians eschew the lending industry.[01:23:50] Does agentic commerce break Affirm, or supercharge it?[01:28:01] A PhD-level financial advisor in everyone's pocket.[01:29:58] How close are we to buying anything through one AI chat?[01:36:32] Improving your coffee: cheap, intermediate, and Bugatti options.[01:44:33] The books every first-time founder should actually read.[01:48:08] Claude Shannon, Ed Thorp, and the joy of playful genius.[01:51:00] Why physical books still beat every digital reading experience.[01:51:44] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dave Rubin of "The Rubin Report" talks about Fox News' Peter Doocy busting out laughing live on-air when Senator John Kennedy gave his hilarious reaction to Kamala Harris advocating for Democrats to try to abolish the electoral college and pack the Supreme Court to give the Democratic Party more political power; CNN's Dana Bash pointing out Pete Buttigieg's hypocrisy live on-air about his outrage over Republican redistricting plans; the New York Times Lulu Garcia-Navarro looking visibly shocked by Graham Platner doubling down on supporting armed political violence to fight what he perceives as fascism; Zohran Mamdani trying to do damage control after Citadel CEO Ken Griffin responded to Mamdani's tax the rich stunt by pulling some of his investment plans for NYC and doubling down on Miami instead; the "Real Time with Bill Maher" crowd going eerily silent while Maher ripped into the Democratic Party for fanning the flames of antisemitism and the hatred of Israel; Elon Musk's viral reaction to the violent chants at the anti-Unite the Kingdom rally that called for Tommy Robinson to be murdered like Charlie Kirk; and much more. Join me for a LIVE Event with Governor Ron DeSantis, plus special appearances by Ben Shapiro, Jillian Michaels, and Adam Carolla on June 11th! Get Tickets Here: https://daverubin.com/events WATCH the MEMBER-EXCLUSIVE segment of the show here: https://rubinreport.locals.com/ Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ Today's Sponsors: Prolon- Prolon's Fasting Mimicking Diet is a revolutionary, plant-based nutrition program that nourishes the body while keeping it in a fasting state. Prolon is offering 15% off their 5-day nutrition program for your post-holiday glow-up. Go to: http://ProlonLife.com/DAVE VanMan - Ditch the corporate chemicals and support your skin healing, made from ingredients so clean you could literally eat them. Go to http://vanman.shop/rubin and use code RUBIN for 15% off your first order.
GLP-1s are the fastest growing drug trend in health right now. But a 30-year fasting study says there's something every user needs to know before their next dose. Dr. Valter Longo has spent 30 years studying aging and longevity at USC, running over 40 clinical trials on what actually makes people live longer and healthier. What he found challenges almost everything the wellness industry is pushing right now, from 16-hour fasting windows to high-protein diets to GLP-1 drugs. In this episode of Habits and Hustle, Dr. Longo breaks down the science behind the Fasting Mimicking Diet (FMD), why 12 hours of fasting beats 16, and what centenarians around the world actually eat. He also shares his latest research on cancer, Alzheimer's, and why your body already has the tools to heal itself if you stop getting in its way. It's time to ask the right questions about the hottest longevity trends that are costing people more than helping them. What's Discussed: (2:01) Who is Dr. Longo and the training behind his research. (3:18) The hypothesis behind why we should be fasting differently. (5:39) What a Fasting Mimicking Diet actually contains and why. (7:27) The difference between the longevity diet and the FMD. (8:30) Why 12 hours of fasting beats 16 every time. (11:18) The hidden risks of skipping breakfast nobody talks about. (15:47) How the FMD resets your body's locked-in weight. (21:12) How the "recipe" behind the FMD was built over 20 years. (29:51) Why the cancer, Alzheimer's, and diabetes versions of FMD are all different. (35:11) The trial showing nearly double survival rates in cancer patients. (38:04) Dr. Longo's real take on protein and why less may mean longer life. (51:24) How often you should actually do the FMD. (53:08) What the research says about fasting and women. (56:40) Dr. Longo's honest breakdown of GLP-1 risks and side effects. (1:16:19) Findings beyond fasting that slow aging. (1:23:21) The four things the FMD triggers that nothing else does. (1:36:31) Why nutrition beats exercise for longevity and why that's not the full story. Thank you to my sponsors!Kion: Visit getkion.com/habits for 20% off. AirDoctor: Head to AirDoctorPro.com and use promo code HUSTLE to get up to $300 off today! AirDoctor comes with a 30-day money back guarantee, plus a 3-year warranty (an $84 value) FREE! AX3®: Visit www.AX3.life to get a 20% discount on your first order with promo code HUSTLE at checkout. Magic Mind: Head over to www.magicmind.com/jen and use code JEN at checkout. Find more from Jen Cohen: Website: www.jennifercohen.com Instagram: @therealjencohen Books: www.jennifercohen.com/books Speaking: www.jennifercohen.com/speaking-engagements Find more from Dr. Valter Longo: Website: https://valterlongo.com/ Instagram: @prof_valterlongo Facebook: Prof. Valter Longo YouTube: @Prof.ValterLongo Fasting Cancer Book: www.valterlongo.com/professor-longos-new-book-fasting-cancer/ Longevity Diet Book: www.valterlongo.com/the-longevity-diet/ The Weight of Longevity Book (Italian): www.amazon.it/ Fasting and the Longevity Revolution Documentary: www.fastingandthelongevityrevolution.com/ Dr. Longo's Foundations: US: www.createcures.org/ Italy: www.fondazionevalterlongo.org/en/
What if one of the most popular health trends in the world, fasting, is actually being done wrong by millions of people? In this powerful and deeply grounded conversation, Darin sits down with world-renowned longevity expert Dr. Valter Longo to cut through the noise surrounding fasting, dieting, and modern health trends. From the dangers of prolonged fasting and skipping breakfast to the science behind the Fasting Mimicking Diet, this episode delivers a reality check rooted in decades of clinical research, not social media hype. They explore the intersection of longevity, cancer, metabolism, and modern lifestyle, unpacking why extreme protocols fail, why simplicity wins, and why aligning with your biology is the true key to a long, disease-free life. What You'll Learn Why most fasting trends are misapplied and potentially harmful The safest and most sustainable fasting window for longevity Why skipping breakfast is linked to increased mortality risk The science behind the Fasting Mimicking Diet (FMD) How fasting impacts cancer cells vs healthy cells The hidden risks of GLP-1 weight loss drugs Why "easy solutions" often lead to worse long-term outcomes The importance of circadian rhythm in metabolism The truth about protein intake and long-term health risks Why slow, consistent change beats every "quick fix" Chapters 00:00:00 – Opening: SuperLife mission and framing the conversation 00:00:32 – Sponsor: Therasage infrared sauna and heat therapy benefits 00:03:16 – Introduction: Dr. Valter Longo and longevity research 00:03:40 – The fasting craze: what's misunderstood 00:04:05 – Documentary discussion: science vs entertainment 00:05:13 – Why education must outweigh entertainment 00:06:19 – The danger of social media health advice 00:07:00 – Food systems, pharma, and systemic health issues 00:07:58 – Why clinical trials matter more than anecdotes 00:08:15 – Framing fasting: trends vs real science 00:08:59 – The problem with DIY fasting 00:10:03 – The safest fast: 12-hour daily fasting explained 00:10:38 – Risks of long fasting: cholesterol, gallstones, mortality 00:11:09 – Why skipping breakfast increases health risks 00:11:49 – 12-hour fasting as the most sustainable protocol 00:12:13 – Modern eating habits: 15+ hour eating windows 00:12:34 – Why extreme diets fail long-term 00:13:37 – Feasibility: why most people won't sustain extremes 00:13:56 – Introducing the Fasting Mimicking Diet (FMD) 00:14:53 – Risks of fasting without personalization 00:15:20 – Why fasting can do more harm than good 00:15:45 – Sponsor: Alkemis Paint, indoor toxicity and non-toxic paint 00:18:42 – Clinical trials: meal timing and metabolic health 00:19:03 – Morning vs evening calorie intake study 00:19:56 – Why late eating disrupts metabolism and sleep 00:20:21 – Epidemiology: skipping breakfast increases mortality 00:21:18 – Circadian rhythm and digestion explained 00:22:11 – Evolutionary biology of eating patterns 00:22:41 – Circadian violations and long-term consequences 00:23:11 – Short-term benefits vs long-term risks 00:24:01 – Why slow progress leads to real results 00:24:49 – Realistic timelines: years, not weeks 00:25:19 – The modern system pushing unhealthy behaviors 00:25:48 – GLP-1 drugs: convenience vs consequences 00:26:13 – The danger of "effortless health" 00:27:13 – Exercise analogy: why effort still matters 00:28:06 – The "pill for everything" mentality 00:28:48 – Finding balance between extremes 00:29:25 – Sponsor: Our Place, non-toxic cookware and health 00:31:12 – Personalization vs one-size-fits-all health 00:31:51 – GLP-1 risks: depression, anxiety, muscle loss 00:32:36 – Natural vs drug-induced weight loss differences 00:33:29 – Rebound weight gain and hormonal suppression 00:34:14 – Supplements vs fixing root causes 00:34:37 – What is the Fasting Mimicking Diet 00:35:05 – Cancer research: fasting and treatment synergy 00:36:13 – How FMD mimics fasting while protecting the body 00:37:06 – Gut health and microbiome benefits 00:38:32 – FMD vs water-only fasting outcomes 00:39:26 – Clinical trials: Crohn's and colitis remission 00:40:03 – Importance of independent research 00:41:20 – Longevity through the lens of fatherhood 00:42:23 – Concerns about AI and children's development 00:43:25 – Social isolation vs digital addiction 00:44:25 – The need for balance in technology use 00:45:10 – AI overdependence and cognitive decline 00:46:18 – Mental health crisis and modern technology 00:47:10 – Reclaiming creativity and human agency 00:48:43 – Fasting and cancer: immune system activation 00:49:53 – Why cancer cells resist fasting signals 00:51:10 – The "desert analogy" for cancer vulnerability 00:52:54 – Combining fasting with therapies 00:54:07 – Future of treatment: precision targeting 00:55:14 – Early detection and personalized interventions 00:56:12 – Where fasting fits in cancer care today 00:57:31 – The protein debate: how much is too much 00:58:17 – Protein intake guidelines explained 00:59:07 – Quality vs quantity of protein 01:00:18 – SuperLife Patreon and accessing exclusive content 01:01:21 – The protein obsession problem 01:02:00 – Children consuming excessive protein 01:03:18 – Portion control and dietary awareness 01:04:07 – Risks of excessive protein intake 01:05:04 – Minimal benefits vs long-term risks 01:06:12 – Longevity populations and low protein intake 01:08:00 – The future of nutrition science 01:12:00 – Final reflections on longevity and health 01:15:00 – Closing thoughts: aligning with biology Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN20 at checkout for 20% off Alkemis: Go to alkemispaint.com and use code DARIN10 for 10% off your order. Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Dr. Valter Longo Website: valterlongo.com Instagram: @prof_valterlongo Get His New Book: Fasting Cancer Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences New Show: Roadmap to Happiness Key Takeaway "The path to longevity isn't found in extreme protocols or quick fixes, it's found in consistency, alignment, and understanding your biology. When you stop chasing shortcuts and start working with your body instead of against it, that's when real transformation happens, not just in how long you live, but in how well you live."
Dietitian Nutritionist Leyla Muedin discusses a Stanford-led randomized controlled trial published in Nature Medicine in which a five-day, calorie-restricted fasting-mimicking diet improved symptoms and inflammatory markers in people with mild to moderate Crohn's disease. In the three-month study of 97 patients, 65 followed monthly five-day cycles of 700–1100 calories/day with plant-based meals, while 32 continued usual diets; about two-thirds of the fasting-mimicking group reported symptom improvement, with fatigue and headaches but no serious side effects, and fecal calprotectin and other inflammatory molecules decreased. She notes bowel rest and the specific carbohydrate diet as additional approaches. The episode also explains how antibiotics can cause diarrhea by disrupting gut bacteria, lists higher-risk antibiotics, offers supportive steps (hydration, BRAT foods, avoiding irritants), recommends Saccharomyces boulardii taken away from antibiotics, and outlines warning signs requiring medical care, including possible C. difficile.
Dave Rubin of "The Rubin Report" talks about Hakeem Jeffries instantly regretting the Democrats win of redistricting Virginia and threatening Florida Governor Ron DeSantis after DeSantis responded directly to Jeffries threat with a redistricting plan of his own that could throw a wrench into Democrats' plans; Scott Jennings getting his CNN panel to go silent as he explains the facts of how distorted and unfair Virginia's redistricting map really is; Democrats Katie Porter and Xavier Becerra humiliating themselves as they are forced to evaluate Gavin Newsom's success at fighting homelessness in California at the most recent California Governor Debate; the New York Times' Opinions' Podcast allowing Hasan Piker to not only justify the murder of United Healthcare CEO Brian Thompson by Luigi Mangione but also make the claim that Brian Thompson was involved in "social murder" without getting any pushback from the hosts; Palantir CEO Alex Karp telling a crowd his brutal assessment of why the murder of United Healthcare CEO Brian Thompson by Luigi Mangione should be a wake-up call to anyone who is trying to preserve Western Civilization; Zohran Mamdani's voters turning against him and suing him to stop his plans to move the Bellevue homeless shelter into the heart of the East Village in Manhattan; and much more. Dave also hosts a special "ask me anything" question-and-answer session on a wide range of topics, answering questions from the Rubin Report Locals community. WATCH the MEMBER-EXCLUSIVE segment of the show here: https://rubinreport.locals.com/ Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ ---------- Today's Sponsors: VanMan - Ditch the corporate chemicals and support your skin healing, made from ingredients so clean you could literally eat them. Go to http://vanman.shop/rubin and use code RUBIN for 15% off your first order. Prolon - Prolon's Fasting Mimicking Diet is a revolutionary, plant-based nutrition program that nourishes the body while keeping it in a fasting state. Prolon is offering 15% off their 5-day nutrition program for your post-holiday glow-up. Go to: http://ProlonLife.com/DAVE
Dr. Valter Longo explains how fasting-mimicking diets make cancer cells vulnerable to treatment while protecting healthy tissue, plus the clinical evidence, safety protocols, and why oncologists remain skeptical.Dr. Valter Longo, author of "Fasting Cancer," breaks down decades of research on using fasting-mimicking diets (FMD) alongside conventional cancer therapies. Cancer cannot be starved but it can be metabolically weakened by limiting resources which a the same time protects healthy cells. A process known as differential stress resistance. We cover: the mechanism behind why this works, clinical trial results in triple-negative breast cancer and other aggressive cancers, the surprising data on weight loss and cachexia, BMI cutoffs and safety protocols, how to approach your oncologist, prevention versus treatment applications, and the cutting-edge "escape pathway" research that could transform personalized cancer treatment. Dr Longo addresses the elephant in the room: why, despite promising results in both mouse models and human trials, this approach faces massive institutional and regulatory barriers to becoming standard of care. Practical, evidence-based information for patients, caregivers, and anyone interested in the intersection of nutrition and cancer biology.
In this episode, Vanessa breaks down the fasting mimicking diet (FMD) — including the exact calories, macros, and protein intake used in the research — and compares it to higher-protein fat loss approaches like protein-sparing modified fasting (PSMF) days.
I veckans avsnitt dyker vi ner i vår fastehärmande kur, inspirerad av Valter Longos banbrytande forskning på Fasting Mimicking Diet. Vi talar om:Vad som händer i kroppen under fastaAutofagi – kroppens smarta återvinningssystemVarför vi växlar mellan att bygga och repareraKopplingen till biologisk ålder och longevityVåra egna resultat – du vill inte missa det här! Hosted on Acast. See acast.com/privacy for more information.
In deze aflevering van Biohacking Talks duiken Eduard en Govert in het Fasting Mimicking Diet (FMD) van professor Walter Longo - een vijfdaagse reset die de voordelen van watervasten biedt zonder de extreme honger en risico's. Je leert over: Het verschil tussen watervasten en fasting mimicking (en waarom FMD veiliger kan zijn) De wetenschap achter autofagie: hoe je lichaam zichzelf opruimt op dag 4 en 5 Waarom biologische leeftijd verlagen vaak draait om één ding: caloriereductie De Goldilocks zone: wanneer caloriereductie werkt en wanneer het averechts werkt (kijk uit bij stress, burn-out of intensief sporten!) Het geheim van glycerol: hoe je vet verbrandt zonder spiermassa te verliezen Eduard's persoonlijke ervaringen: van ijskoud in bed tot cognitieve scherpte en slaapscores boven de 90 Waarom je dit NIET zomaar moet proberen als je ongetraind bent of in een stressfase zit Een fascinerende discussie over metabolische flexibiliteit, het belang van seizoensgebonden vasten, en waarom de Prolon-box misschien slim gemarkeerd is - maar dat je het waarschijnlijk ook zelf kunt samenstellen met wat AI-hulp.
You've been told your A1C is "a little high." Maybe your doctor said "watch your diet" and sent you home. Maybe you've been on medication for years and nothing is actually getting better. If that sounds familiar, this episode is going to change how you think about your health. In this episode of Medical Disruptor, Dr. William Hsu explains why type 2 diabetes is fundamentally a disease of cellular aging and why that changes everything about how we should treat it. He breaks down the Nobel Prize-winning science of cellular autophagy, what actually happens inside your body during a prolonged fast, and why your cells are already programmed to repair and regenerate when given the right conditions. He also introduces the Fasting Mimicking Diet, a clinically validated five-day nutritional protocol backed by 48 human clinical trials, that activates your body's built-in repair system without requiring a complete lifestyle overhaul. This is not another conversation about eating less and moving more. This is about giving your body what it needs to actually heal. What you will learn: -Why insulin resistance starts 10 to 20 years before your blood sugar looks abnormal -What diabetes remission actually means and why most patients are never told it is possible -How 15 days per year of this protocol reduced biological age by a median of 2.5 years in clinical trials -The one lab marker most doctors skip that could change your entire health picture Your body has the ability to heal. Most patients are never told that. This episode changes that. Get your LMNT sample pack: http://drinklmnt.com/disruptor Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 00:00 Why a Harvard Endocrinologist Left Academic Medicine 02:00 What Medicine Gets Wrong About Diabetes 07:00 Why Diabetes Is an Age-Related Disease 13:30 The Nobel Prize Science Behind Your Body's Repair System 19:30 What Is the Fasting Mimicking Diet 25:00 The Clinical Evidence: 48 Trials and Counting 31:00 Pre-Diabetes and False Reassurance: The "Touch of Sugar" Problem 36:00 Why Lifestyle Is One Line and Drugs Are Ten Pages 44:00 Where to Find Dr. Hsu and How to Get Started Guest Links: FB: https://www.facebook.com/prolonfmd/ Website: https://l-nutra.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Longevity expert Dr. Valter Longo dives deep into the science behind the Fasting Mimicking Diet and why it holds a significant edge over traditional water-only fasting. Dr. Longo explains how the FMD is engineered to trigger cellular cleanup while providing essential nutrients that protect muscle mass and maintain gut integrity—avoiding the leaky gut risks seen in water-only trials WHAT YOU WILL LEARN Safety and Compliance: Unlike water-only fasting, which can cause hypotension and hypoglycaemia, the FMD is designed to be safer and much easier for the average person to complete. Gut Health Protection: Emerging research suggests that water-only fasting can actually increase leaky gut symptoms in mice Muscle Maintenance: The FMD utilises specific carbon sources like glycerol to support glucose production, which prevents the body from breaking down muscle tissue for energy during the fast. Psychological Reset: Beyond the biology, the five-day protocol serves as a powerful psychological stop sign TIMESTAMPS: 0:38 The Slave to the Meal 2:10 The Leaky Gut Discovery 4:54 Training the Teenage Brain 6:22 The Power of the Pause VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.
We are pleased to welcome Dr Valter Longo to this episode of Living Well with MS. Dr Longo is the scientist behind the Fasting Mimicking Diet. He is a bio-gerontologist and cell biologist serves as a professor at the USC Davis School of Gerontology and as the director of the USC Longevity Institute. He is the creator of the fasting-mimicking diet, a program that claims to mimic the effects of periodic fasting. To read Dr Longo's full bio, click here. Originally broadcast in 2020, this episode has been edited to remove out-of-date content and reuploaded in 2026 to ensure it remains relevant and useful. 02:08 Today's rising fascination with fasting diets 03:50 Main differences between the fasting-mimicking diet and other fasting diets 05:03 Diving into blue zones, where a higher percentage of the population lives to 100 06:55 The correlation between the centenarians and people who are fasting 11:04 Does fast mimicking help people with MS live better and longer? 14:03 The different types of fast-mimicking diets including 5:2, 16:8 and occasional water fasting 24:54 What should we eat between fasts? 29:28 What is the ProLon diet, and for those on a budget, how can peopel get some of the benefits on their own?
If you're tired of taking handfuls of diabetes medications every day and watching your health decline anyway, this episode is for you! What if you could get off insulin, Metformin, Ozempic, and all your other diabetes meds while actually lowering your blood sugar? Sounds impossible, right? But it's not only possible, it's happening for thousands of people right now. And that could include you! In this episode, Dr. Jeffrey Hockings, founder and CEO of Diabetes Reversal Group, reveals the patented protocol that's helped over 10,000 people completely reverse type 2 diabetes and get off all their medications. Dr. Hockings shares the exact foods, supplements, and lifestyle strategies that work, plus real patient stories, like a man who went from taking over 300 units of insulin daily to zero medications in just six months. Listen to this episode and start your journey to medication-free health today! For show notes, visit https://fivejourneys.com/podcasts/how-to-stop-taking-metformin-insulin-and-ozempic-for-good/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun Reverse Chronic Diseases using Allulose, with Neil Gyte Lose Weight By Improving Your Leptin Sensitivity, with Dr. Bindiya Gandhi Lose Weight By Getting Healthy, with Ben Azadi
Dave Rubin of "The Rubin Report" talks to Stephen A. Smith about his potential plans to run for president as a Democrat in the 2028 election; why Democrats like Gavin Newsom, Kamala Harris, Kathy Hochul, Hillary Clinton and others continue to pander to black voters by insulting them and their intelligence; why he is so unimpressed by the potential Democrat nominees for the 2028 election and why he is confident that he could beat Gavin Newsom, Kamala Harris, Pete Buttigieg, and Alexandria Ocasio-Cortez; why so many people think that Gavin Newsom is a shapeshifting and inauthentic politician and if he trusts him; why liberal celebrity activists like Mark Ruffalo keep thinking that if we only tax the rich or pass a billionaire wealth tax governments will be able to solve all the problems of society; why he thinks Zohran Mamdani is doomed to fail and why his response to the snowball attack on NYPD officers is a bad sign for New York City police officers; and much more. Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ ---------- Today's Sponsors: Shopify - Turn your big business idea into money with Shopify on your side. Shopify is the commerce platform behind millions of businesses around the world from household names to brands just getting started. Go to Shopify and sign up for your one-dollar-per-month trial and start selling today at Go to: http://shopify.com/rubin Prolon - Prolon's Fasting Mimicking Diet is a revolutionary, plant-based nutrition program that nourishes the body while keeping it in a fasting state. Prolon is offering 15% off their 5-day nutrition program for your post-holiday glow-up. Go to: http://ProlonLife.com/DAVE
Dave Rubin of "The Rubin Report" talks to Glenn Beck about Abraham Lincoln's early life, personal struggles, faith, and moral evolution during the Civil War; why Lincoln was hated long before he ended slavery; Lincoln's leadership, suspension of habeas corpus, and preservation of the Union; the little known first planned assasination attempt of Lincoln; how John Wiles Booth ended up in a photo with Abraham Lincoln; his new AI project built on primary founding-era documents to create an AI George Washington to analyze American history without modern bias; how artificial intelligence can be used to recover truth rather than rewrite it; and much more. Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ ---------- Today's Sponsors: Prolon - Prolon's Fasting Mimicking Diet is a revolutionary, plant-based nutrition program that nourishes the body while keeping it in a fasting state. Get a 15% discount and your bonus gift when you subscribe to their 5-Day Program! Go to: http://ProlonLife.com/DAVE Parasite Cleanse -The Wellness Company has a way to fight back against parasites. A Nobel prize winner now in a parasite cleanse combo, that wipes out these invaders to help keep you and your family safe. Rubin Report viewers can save up to $90 and get FREE shipping at checkout when they use code: RUBIN. Go to: https://TWC.health/RUBIN and use CODE: RUBIN
Can you have the benefits of fasting (and more!) without starving? You've probably heard that fasting means giving up food completely, enduring hunger, risking muscle loss, and hoping you can stick it out long enough to see results. But what if you could eat breakfast, lunch, dinner, AND snacks while your body still thinks it's fasting? In this episode, Renee Fitton, Director of Education at Prolon and a leader in nutrition science and longevity, reveals how fasting mimicking lets you get all the benefits of a 5-day water fast without the hunger, muscle loss, or safety risks. If you've struggled with traditional fasting or want a more sustainable way to support weight loss, autophagy, and even reverse your biological age, this episode will change how you think about fasting forever. Listen now and start fasting smarter today! For show notes, visit https://fivejourneys.com/podcasts/why-eating-while-fasting-could-give-you-better-results/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes: Leverage Ketosis and Fasting to Reverse Disease, with Ben Azadi Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun Why 16 Hours Isn't Enough for True Fasting Benefits, with Dr. Chris Rhodes Try Keto for Optimal Health, with Robert & Crystal Sikes
A tech founder's health fell apart, and the fix didn't come from a supplement stack or another glossy wellness trend. It started with a hard look at seed oils, blood sugar spikes, and the way ultra-processed “healthy” foods quietly inflame the body. That reckoning led Vinny Lingham to the carnivore community, to measurable drops in HS-CRP, and ultimately to making Animal, a documentary that challenges popular diet narratives and asks a simple question: what if controlling insulin and inflammation solves most of what's making us sick?We walk through the turning points: how grain-finishing changes the fat you eat, why grass-fed and wild options can shift omega ratios, and how a meat-first elimination approach reveals which foods actually trigger symptoms. We trade notes on going strict for a few months, then reintroducing dairy or berries and letting data—not dogma—guide the plan. The environmental story gets a sober look too, from methane talking points to the deeper damage of monocrop agriculture, and why regenerative grazing restores soil, cycles nutrients, and supports real biodiversity.Behind the scenes, Vinny shares how he funded the film himself, navigated platform roadblocks, and kept the message focused on personal agency over ideology. We also map a realistic spectrum: lion diet on one end, ketogenic and animal-based through the middle, and targeted carbs for sport and lifestyle on the other—always anchored by protein quality, stable fats, and minimal seed oils. If you've wondered why you're tired, hungry, and inflamed despite “eating clean,” this conversation offers a clear, testable path back to strength and steady energy.If the episode resonates, follow the show, share it with a friend, and leave a review with one change you're making this week. Your story might help someone else start theirs.https://www.animal.movie/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Blu...
Today I'm joined by Professor Valter Longo to unpack what actually slows biological ageing, and what most women are getting wrong about fasting, protein, and diet. We explore the difference between chronological age and biological age, how biological ageing is measured, and why chasing extreme fasting or high-protein trends may quietly undermine long-term health. Professor Longo shares decades of research behind the Fasting Mimicking Diet (FMD), explains why most popular fasting protocols may increase cardiovascular risk, and outlines the dietary patterns consistently linked to the world's longest-living populations. This conversation cuts through longevity hype with evidence from human trials, centenarian studies, and 100 years of ageing research, offering a grounded, practical framework for improving healthspan without extremes. WHAT YOU'LL LEARN • The real difference between chronological age and biological age – and how it's measured • Why blood biomarkers may be more reliable than epigenetic ageing clocks right now • What organ-specific ageing clocks reveal about hidden health risks • How long it actually takes to activate meaningful autophagy in humans • Why most intermittent fasting protocols may increase heart disease risk • The science behind the 5-day Fasting Mimicking Diet (FMD) • FMD vs water fasting: gut health, muscle preservation, and safety • Why skipping breakfast is linked to higher cardiovascular mortality • The optimal daily eating window for longevity (and why 12 hours matters) • How often to use FMD for longevity, metabolic health, and disease prevention • Why excess protein may accelerate ageing and disease risk • How much protein humans actually need for longevity • The ideal macronutrient balance for healthspan and lifespan • How nutrition consistently outperforms exercise for lifespan extension • Practical longevity habits around sleep, stress, and lifestyle timing Timestamps 00:00 Intro: Biological Age vs Chronological Age 04:03 Organ-Specific Ageing: Why One Age Score Can Be Misleading 06:15 Autophagy Explained: How Long It Really Takes in Humans 08:59 The Longevity Diet & Fasting Mimicking Diet Explained 11:26 Why Most Fasting Protocols May Be Harmful Long-Term 16:58 Skipping Breakfast, Cholesterol & Heart Disease Risk 18:36 Water Fasting vs FMD: Gut Health, Microbiome & Muscle Loss 35:03 Protein Intake Myths: Muscle, Ageing & Disease Risk 42:46 Sleep, Stress & Lifestyle Factors That Extend Healthspan VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible: • MitoQ NAD+
In this episode of The Vibe With Ky Podcast, Ky asks Renee Fitton why diet rules stop working in midlife. Learn how to reset metabolism and fix brain fog.This season is presented by Sucreabeille. Check out Ky's exclusive scent HERE!Ky and Registered Dietitian Renee Fitton discuss why perimenopause causes sudden weight gain and systemic inflammation. They explain the science of fasting mimicking diets and how a short-term nutrition reset can trigger cellular cleanup without the stress of starvation.Key Takeaways:Why calorie restriction often backfires during menopause.How the Fasting Mimicking Diet reduces inflammation markers.The link between anxiety, caffeine, and processed foods.Renee Fitton Instagram: Renee's Instagram - @FittonNutritionProlonJoin The Vibe With Ky:Official WebsiteInstagram - @TheVibeWithKyPatreonFacebook SubscriberDisclaimer: I am not a licensed mental health professional. Please seek professional help if needed.
Pain that creeps in, brain fog that lingers, weight that resists every effort—what if the culprit isn't “just getting older,” but inflammaging? We sit down with Dr. Shivani Gupta, author of The Inflammation Code, to connect ancient Ayurvedic wisdom with modern science and map out a practical plan for cooling chronic inflammation. Instead of chasing symptoms, we focus on the terrain: circadian rhythm, gut health, stress load, and daily rituals that nudge the body back into repair mode.Shivani shares a refreshingly doable morning routine—intention setting, hydration, tongue scraping, and early sunlight—that anchors your clock and digestion. She then walks us through soothing evening practices like dry brushing, abhyanga oil massage, and mineral baths to move lymph, calm the nervous system, and deepen sleep. We explore the concept of “mental inflammation,” how chronic stress inflames the body, and why short decompression breaks plus adaptogens such as ashwagandha and shatavari help regulate mood and resilience.We also dive into the science of turmeric: how curcumin modulates NF-kB and TNF-alpha, supports the gut lining, affects AMPK and sirtuins, and promotes neurogenesis and mitochondrial health. You'll hear when food sources are enough, when supplements make sense, how to boost absorption with black pepper and healthy fats, and key safety notes for blood thinners and kidney stone risk. For midlife women, Shivani emphasizes sleep as the non-negotiable lever—assessing progesterone, using calming botanicals, and protecting the 10–2 overnight window where the body clears inflammation.If you're ready to replace quick fixes with smart rhythms, spice up your meals with potent anti-inflammatory allies, and finally feel your energy return, this conversation offers a clear roadmap. Subscribe, share with a friend who needs actionable hope, and leave a review telling us which ritual or spice you'll try first.https://fusionaryformulas.com/ (Use LUFKIN15 for 15% off)Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Blu...
What if the key to living for over 125 years is already inside you, just waiting to be turned on? Every cell in your body has a built-in aging clock that's ticking down with each passing day. But here's the surprising part: you have a gene that could slow or even reverse that clock, and it's been deliberately shut off. In this episode, Dr. Bill Andrews, a molecular biologist and longevity researcher who discovered the human telomerase enzyme, explains why your telomeres shorten as you age and how activating your body's dormant anti-aging gene could extend both your lifespan and healthspan. If you want to understand the real science behind aging and what you can actually do about it, this conversation reveals breakthrough research that might just change everything you thought you knew about getting older. Listen now and start activating your longevity today! For show notes, visit https://fivejourneys.com/podcasts/live-longer-by-activating-your-bodys-anti-aging-gene/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes Live Longer & Reverse Aging, with Dr. Kara Fitzgerald Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun Longevity and mTOR: What the Science Says, with Dr. Robert Lufkin How You Could Live Longer With This Nobel Prize-Winning Molecule, with Chris Burres Aging with Vitality and Strength, with Dr. Sandra Scheinbaum How Toxins Accelerate Aging and Shorten Your Lifespan, with Dr. Mark Hyman Reversing Aging: The Power of NAD+, with Dr. Nichola Conlon Hormones for Healthy Aging, with Dr. Daved Rosensweet Slow Aging by Optimizing These Redox Reactions, with Dr. Monisha Bhanote
What if the most powerful biohack is simply getting the morning sun in your eyes and letting your wearables prove it works? We explore Medicine 4.0 with Steven Stavrou DCM, a South African physician-biohacker who blends Chinese and functional medicine with hard data, showing how ancestral habits and modern metrics can drive prevention, performance, and genuine wellbeing.We start with incentives and shift them toward staying well, then build a plan from baseline labs, HRV, sleep, and body composition. You'll hear why the first 90 minutes of the day set your circadian rhythm, how breath work and heat-cold routines can move stress scores, and how to personalize movement so VO2 gains don't cost you muscle or hormones. We unpack a practical supplement strategy—vitamin D, the right magnesium forms, creatine, and sleep-supportive amino acids—while making the case for quality over quantity and partnering with trusted clinicians instead of buying mystery gummies online.From there, we connect mitochondria to cognition and mental health, advocating for a “cognoscopy” to objectively track brain performance. We discuss the evolving landscape of peptides—BPC-157, TB-500, CJC-1295, and more—highlighting both the promise and the need for careful governance. Purpose and community aren't afterthoughts; they're central to metabolic health and resilience. With coaching as the bridge, complex plans become small, repeatable wins that compound over months into sustainable transformation.If you're ready to stop guessing and start measuring—while keeping your routine simple and human—this conversation offers a clear path. Subscribe, share with a friend who needs a reset, and leave a review with the one habit you're adding this week.https://stevestavs.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Blu...
Dave Rubin of "The Rubin Report" talks about "Shark Tank's" Kevin O'Leary telling Fox News' Will Cain why the exposing of the massive fraud in California will quickly end Gavin Newsom's political career and 2028 election chances; Elon Musk and Palantir co-founder Joe Lonsdale sharing the biggest tell that someone is committing fraud; Donald Trump announcing his renewed push to investigate Ilhan Omar for her possible involvement in the Minnesota fraud scandal enveloping the Somali community, so that she can be deported; Don Lemon getting in over his head for his involvement in an anti-ICE protest in a Minneapolis church; Don Lemon's man-on-the-street interview blowing up in his face after he attempted to tell people that coming to America illegally was not a crime; Thomas Sowell giving the cold facts about the dangers of too much immigration; and much more. WATCH the MEMBER-EXCLUSIVE segment of the show here: https://rubinreport.locals.com/ Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ ---------- Today's Sponsors: Noble Gold Investments - Whether you're looking to roll over an old 401(k) into a Gold IRA or you want physical gold delivered right to your home Noble Gold makes the process simple. Download the free wealth protection kit and open a new qualified account and get a FREE 10-ounce Silver Flag Bar plus a Silver American Eagle Proof Coin. Go to http://DaveRubinGold.com Venice.Ai - Use Ai that doesn't spy on you or censor the AI. Ai is valuable and you shouldn't need to give up your privacy to use it. Go to https://venice.ai/dave and use code DAVE to get 20% off a pro plan and enjoy private, uncensored AI. Prolon - Prolon's Fasting Mimicking Diet is a revolutionary, plant-based nutrition program that nourishes the body while keeping it in a fasting state. Prolon is offering 15% off their 5-day nutrition program for your post-holiday glow-up. Go to: http://ProlonLife.com/DAVE
Feeling “fine” is not a plan. We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your ultimate asset can change the arc of your life. We dig into the core four foundations (sleep, diet, exercise, relationships), the hidden risks behind “normal for your age” labs, and the personalized strategies that help you extend your prime years, not just your lifespan.Sandeep explains the gaps in standard panels and why markers like lipoprotein(a), ApoB, and early insulin resistance can quietly raise cardiovascular risk for decades. He shares a practical framework for advanced therapies—rapamycin, peptides, red light, hyperbaric oxygen—rooted in evidence, safety, access, and intent, with explicit stop criteria to avoid blind experimentation. We talk through what it takes to turn vague advice into precise action: strength training as a glucose sink, protein targets, VO2 max, and sleep protocols tailored to your biology and lifestyle.We also explore the evolutionary case for a longer, more productive middle life. Wisdom tends to peak in the 50s and 60s, exactly when chronic disease often accelerates. With the right diagnostics, coaching, and accountability, it's possible to keep the energy of a 30-year-old while preserving the judgment of a seasoned leader. From there, we shift to AI's growing role in medicine: clinical copilots that surface patterns, agentic systems that handle routine care, and how empathy at scale could emerge alongside human guidance for high-stakes decisions.If you're ready to manage health with the same rigor as your wealth, this conversation offers a roadmap: better measurement, longer conversations, smarter tools, and a clear strategy that compounds over time. Subscribe, share with a friend, and tell us—what metric will you start tracking this week?https://www.velocityhealthclinic.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Blu...
What if the core of fatigue, brain fog, and “getting old” is really an oxygen problem? We sit down with Brad Pitzele to unpack how exercise with oxygen therapy (EWOT) and red and near-infrared light can reboot cellular energy, open microcirculation, and dial down inflammation in a way that's fast, practical, and measurable. Brad's story moves from autoimmune arthritis and melanoma risk to a sustainable routine that restored clarity and stamina—without spending hours in a chamber or crushing workouts.We break oxygen down to first principles: aerobic vs anaerobic ATP, why lactic acid spikes when cells are starved, and how oxygen use declines about 1% per year after 25. From there, we get tactical. EWOT leverages exercise-driven vasodilation to flood plasma with oxygen, reaching capillary “nooks and crannies” red blood cells can't. Hyperbaric oxygen raises partial pressure and helps specific cases like non-healing wounds or those unable to exercise, but EWOT's 15-minute sessions, lower cost, and vessel-friendly physiology often make it the go-to choice for daily use.Light therapy adds the second lever—demand. Red and near-infrared wavelengths signal mitochondria to take in more oxygen and make more ATP, supporting skin renewal, muscle recovery, and cognitive performance. Use them together for a supply-and-demand loop: EWOT first, then light for longevity; light first, then EWOT for performance. We also cover safe ramp-ups to avoid Herxheimer reactions, how to start if you're deconditioned, what biomarkers to track, and myths to ditch about “no pain, no gain” and red light overdosing.If you've wondered whether brain fog can lift, whether energy can return without heroic protocols, or whether oxygen and light can support long COVID, Lyme, or cognitive decline strategies, this conversation offers clear steps and honest limits. Subscribe, share with someone who needs hope and a plan, and leave a review with your top question so we can tackle it next.https://www.onethousandroads.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
Lifestyle Shifts Supporting Longevity and WellbeingTaking care of your health can feel overwhelming, especially when so many approaches promise big results but don't last. If you've ever wondered why healthy habits are hard to sustain, this episode offers a grounded and realistic perspective.In this episode of the Free to Be Mindful Podcast, Licensed Therapist and Mom Coach Vanessa De Jesus Guzman is joined by Renee Fitton, a longevity dietitian and Vice President of Growth at L-Nutra, for an honest conversation about lifestyle shifts that support longevity, wellbeing, and mental health - without extreme dieting or pressure.Renee breaks down what longevity nutrition really means, why living longer isn't helpful if we don't feel well along the way, and how small, intentional changes can support physical health, brain health, and emotional wellbeing over time. The conversation includes an introduction to fasting mimicking approaches, including ProLon, while emphasizing safety, muscle protection, and sustainability... especially for women navigating midlife changes.Vanessa and Renee also explore how mindset, gratitude, and intention-setting shape how we age and how we experience everyday life.In this episode, we talk about:Lifestyle shifts that support longevity and wellbeingWhat longevity nutrition is, and what it isn'tHow fasting mimicking works and who it may be appropriate forWhy muscle protection and metabolic health matter as we ageThe connection between mindset, gratitude, and brain healthWhy small, consistent changes matter more than drastic overhaulsThis episode is for moms and busy professionals who want to care for their health in a realistic, compassionate way, without adding more pressure to an already full life.STAY CONNECTED WITH RENEE: https://www.instagram.com/fittonnutrition/https://prolonlife.com/ https://l-nutra.com/ DISCOUNT CODE:
Fasting Mimicking for Longevity, Weight Loss & Hormonal Balance with Renee FittonHave you ever wondered how to get the powerful benefits of a 5-day water-only fast—without having to give up food entirely? In this fascinating episode, we're joined by Renee Fitton, longevity dietitian and Director of Education at L-NUTRA, to explore the science and strategy behind fasting mimicking.You'll learn how the Fasting Mimicking Diet (FMD) delivers the same biological benefits as prolonged fasting—like fat burning, autophagy, cellular rejuvenation, and metabolic reset—without the intensity or deprivation of traditional fasting.Learn more or try it yourself
What if the most powerful health checkup you ever had happened at your kitchen table, not a clinic? We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade at‑home blood testing and intelligent coaching can change outcomes before a crisis hits.We start with the problem he saw repeatedly: people arriving late with preventable chronic disease. That urgency drives a practical roadmap for what to measure and why. You'll hear a clear breakdown of high‑value biomarkers—HbA1c for glucose trends, ApoB and the ApoB to ApoA1 ratio for cardiovascular risk, and thyroid markers for therapy tuning—and why total cholesterol alone often misleads. Tosh explains how accuracy is maintained through CLIA‑accredited labs and transparent methods, addressing trust in a post‑Theranos world. We also dig into biological age: how markers like hs‑CRP, HbA1c, and sex hormones push it up or down, and the specific lifestyle levers that can nudge it younger over the next 90 days.Then we open the hood on Sai, an AI longevity expert trained on a clinician‑curated knowledge base. Instead of scraping the noisy web, Sai reads your longitudinal labs, medications, and context to deliver personalized, evidence‑based guidance. Think trend detection for creeping glucose, stubborn ApoB, or hidden inflammation—and concrete next steps that you can take today. Looking ahead, Tosh shares what's next: home hardware that brings instant panels into your routine and a vision of predictive health where alerts trigger action long before symptoms do.If you want to cut through hype, track the markers that matter, and pair credible data with smart coaching, this conversation will give you the playbook. Subscribe, share with a friend who's optimizing their health, and leave a review with the one biomarker you plan to track this year.Note: I am an advisor to Siphox but I only advise those companies whose products I would use for myself and family.https://siphoxhealth.com/lufkinFASTING CHALLENGE: https://robert-lufkin.mykajabi.com/fast?ref=RLLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdSubstack: https://robertlufkinmd.substack.com Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
Does healthy eating feel impossible? Do you keep starting with good intentions only to end up overwhelmed, confused, and off track?In this episode, we explore why so many people struggle to eat well in a world full of conflicting advice. When every diet promises answers and information is coming from all directions, it's easy to feel stuck and frustrated with yourself.This conversation looks at what's really behind the overwhelm, why willpower isn't the solution, and how to move forward without waiting for the perfect diet. We also touch on fasting and how to think about it in a way that's grounded, realistic, and sustainable.If you've been caught in cycles of starting over or quietly blaming yourself, this episode offers clarity and a calmer way forward.Ashley Bizzell, is a registered dietitian and certified diabetes care and education specialist with over fifteen years of experience.Timestamps:(00:00) Introduction(01:13) Eliminating Sugars & Processed Foods(03:34) The Science & Benefits of Fasting(07:59) Fasting Mimicking Diet(14:49) Addressing Obesity & Metabolic Health(18:43) Mental Health & Nutrition Connection(24:04) Daily Nutrition & Hydration Tips(32:30) Healthy Snacking Alternatives(35:08) Extreme Diets: Risks and Realities(36:32) Closing Thoughts and ReflectionsGet the FREE Move Your Mind Masterclass here:go.nickbracks.com/moveyourmindAccess FREE Move Your Mind training here:https://go.moveyourmind.io/trainingConnect with Nick:Instagram: https://instagram.com/nickbracksWebsite: http://nickbracks.comEmail: contact@nickbracks.comConnect with Ashley:https://www.instagram.com/thedeetsondelicious Hosted on Acast. See acast.com/privacy for more information.
What if the most powerful “sugars” aren't fuel at all, but messages your immune system has been waiting to hear? We sit down with Dr John Lewis, a former professor whose lab uncovered striking cognitive improvements in people with moderate to severe Alzheimer's after 12 months on a formula built from aloe and rice bran polysaccharides. The science takes us beyond calories and cravings into complex carbohydrates as signaling molecules—shaping inflammation, immune balance, and possibly neuroplasticity.We unpack polysaccharides 101, separating starch from functional giants like aloe acemannan and rice bran compounds. You'll hear how these dense, 3D structures can influence CD4/CD8 ratios, natural killer cell activity, TNF-alpha, VEGF, and even CD14 cells tied to neural repair. The clinical story is matched by lived moments from caregivers who witnessed language and daily function return. We also dig into why conventional funding passed on this line of research, the dominance of amyloid-focused paradigms, and the gap between public talk about nutrition and what actually gets resourced.If you've wondered whether food could deliver these effects, we cover the practical realities: aloe gel is mostly water, rice bran is milled off white rice, and even daily brown rice may not supply meaningful doses—especially for older adults managing chronic inflammation. That's where concentrated, third-party tested, GMP-produced supplementation can fit: small grams-per-day inputs that favor immune modulation without stimulants or sugar spikes. Along the way we explore prevention, aging, and how steady immune signaling may guard brain health long before problems start.Subscribe for more deep, evidence-led conversations on brain health, nutrition science, and longevity. If this episode challenged your view of “sugar,” share it with a friend and leave a review to help others find the show.https://drlewisnutrition.com/ Use "Lufkin10" for 10% off.Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdSubstack: https://robertlufkinmd.substack.com Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
Show notes: (0:00) Intro (0:56) Dr. Longo's surprising path from music student to aging expert (2:00) Early yeast studies and the 10x lifespan breakthrough (3:56) Launching the Fasting Mimicking Diet and supporting clinical trials (6:15) The dangers of long-term calorie restriction and yo-yo dieting (12:18) Why 12-hour fasting is safer than 16+ hours (18:22) Key differences in fasting for women (20:52) What's actually in the Fasting Mimicking Diet (23:41) How often to do it and who benefits most (28:47) Regenerating organs with stem cells and fasting (34:55) The Longevity Diet (38:11) Legumes, protein levels, and real-world advice (45:08) Fasting and cancer: what early research shows (48:15) Where to learn more from Dr. Longo (49:00) Outro Who is Dr. Valter Longo? Dr. Valter Longo is the Edna M. Jones Professor of Gerontology and Biological Sciences and Director of the Longevity Institute at the USC Leonard Davis School of Gerontology, a leading center for aging and disease research. Trained in biochemistry at the University of North Texas and UCLA, with postdoctoral work under longevity pioneers Roy Walford and Caleb Finch, Dr. Longo has built a multidisciplinary research career spanning genetics, immunology, endocrinology, and molecular biology. His laboratory has identified key genetic pathways that regulate aging and demonstrated how targeting these pathways can reduce disease risk and progression in both animal models and humans, including novel dietary and genetic strategies that protect healthy cells while making cancer cells more vulnerable to treatment. Dr. Longo is widely known for developing the fasting mimicking diet, a five-day periodic dietary intervention shown in randomized clinical trials to reduce markers associated with aging and chronic disease, while promoting stem cell–based regeneration and longevity. His work has earned numerous prestigious awards, including the Glenn Award for Aging Research, and in 2018 he was named one of Time Magazine's 50 most influential people in health care. Deeply committed to public health and accessibility, Dr. Longo donates all proceeds from his bestselling books, including The Longevity Diet and Fasting Cancer, to research and education through his foundations in Milan and Los Angeles, advancing affordable strategies to prevent disease and extend healthy lifespan. Connect with Dr. Longo: Website: https://valterlongo.com/ https://l-nutra.com/ Facebook: https://www.facebook.com/profvalterlongo/ IG: https://www.instagram.com/prof_valterlongo/ Grab a copy: https://tinyurl.com/4h4mspmt https://tinyurl.com/j23u989b Links and Resources: Peak Performance Life Peak Performance on Facebook Peak Performance on Instagram
What if the root cause of our most devastating chronic diseases—from Alzheimer's and cardiovascular disease to diabetes and cancer—could be traced back to the same cellular structures? And what if these tiny organelles hold the key to understanding how we age and potentially extending our healthspan?Dr. Hemal Patel, Professor in the Department of Anesthesiology at UC San Diego School of Medicine, takes us on a fascinating journey into the world of mitochondria. Far from being mere "powerhouses of the cell" as we learned in school, these ancient bacterial descendants play sophisticated roles as gatekeepers of cellular life and death, potential drivers of cell differentiation, and central players in understanding chronic disease.When functioning properly, mitochondria form interconnected communities within our cells—appearing like strings of pearls in heart cells, which devote a remarkable 30% of their volume to these energy-generating structures. But when these connections break down, disease follows. Dr. Patel explains how every chronic condition can be viewed through the lens of energy imbalance, with mitochondria at the center of this critical equation.Perhaps most exciting is the breakthrough technology Dr. Patel's team has developed: a simple blood test called MeScreen that can assess mitochondrial function without invasive biopsies. Using just a few drops of blood, this revolutionary approach reveals each person's unique mitochondrial signature, offering personalized insights that could transform how we approach health optimization and disease prevention.Whether you're curious about the fundamental biology of life, seeking to understand chronic disease, or interested in cutting-edge approaches to longevity, this conversation will forever change how you think about the trillions of tiny organelles powering every aspect of your existence. Discover why supporting these ancient symbionts might be the missing link in our pursuit of longer, healthier lives.https://mescreen.com/cart/47561239626013:1?discount=&ref=emssndtq (Use the code MITOHEALTH100 for $100 off)Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
Unlock the secrets to a longer, healthier life with our special guest, Kevin Ellis, the Bone Coach. This episode dives deep into the critical importance of bone health, far beyond just keeping you upright. From blood cell production to immune system support and mineral storage, Kevin explains how your bones play a vital role in your overall well-being. Learn why early bone density scans (DEXA scans) are crucial and how conditions like osteoporosis and osteopenia can silently impact your life quality without proactive monitoring.Explore the hidden connections between inflammation, aging, and chronic diseases and discover how everyday factors like gluten, seed oils, and insulin resistance can erode your skeletal strength. Kevin shares actionable advice on diet, physical activity, and nutrient intake, emphasizing the power of weight-bearing exercises and resistance training. Especially important for older women, these strategies can dramatically enhance bone density and quality, making a significant difference in your health as you age.Finally, Kevin debunks common myths about osteoporosis treatment, advocating for a holistic approach over traditional medications like calcium and vitamin D supplements. From gut health to personalized exercise plans, he unveils a comprehensive blueprint for preventing bone loss and improving bone quality naturally. Plus, don't miss out on Kevin's Stronger Bones programs and a free masterclass offering invaluable resources to start your journey toward stronger, healthier bones. Join us and take the first step towards a resilient, active future!https://bonecoach.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
What if you could see your inflammation—and your pace of aging—from your kitchen table? We sit down with Bob Messerschmidt, an optical engineer turned Apple platform architect who helped seed Apple Health and the Apple Watch, then left to build a simple at-home device that measures ESR, a century‑old inflammation marker with fresh relevance for longevity.We unpack why chronic inflammation drives heart disease, stroke, neurodegeneration, and metabolic dysfunction, and why a single, trackable number can change behavior more than any abstract advice. You'll hear a clear breakdown of ESR vs CRP: how CRP reacts fast to single-protein changes while ESR integrates multiple inflammatory pathways over several days, often acting like a steadier signal for lifestyle experiments. We explore compelling evidence that ESR rises with age in Western populations—functioning as a biological clock—yet flattens in agrarian cohorts, underscoring how environment and habits accelerate “inflammaging.”Beyond theory, we get practical. Our guest shares what actually lowers ESR: meaningful weight loss, GLP‑1 therapies, omega‑3 rich fish, better sleep, daily movement, strength training, stress control, and even tart cherry juice. We talk about the design constraints that make wrist sensors tricky, why Apple prioritizes validation over speed, and how bringing blood-based testing into the home removes friction that once sidelined ESR in centralized lab workflows. With more than ten thousand tests across a diverse user base, the team is preparing anonymized insights and research in underserved communities to show which interventions move the needle in the real world.If you want a reliable, weekly feedback loop that ties your choices to measurable change, this conversation maps the path. Subscribe, share with a friend who cares about longevity, and leave a review to help more people discover smarter ways to measure and lower inflammation.https://corhealth.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
If you've tried every longevity hack and still feel like something's missing, this episode is for you! The Nobel Prize-winning molecule ESS60 could be the breakthrough you've been searching for. In this episode, Chris Burres, founder and chief scientist at My Vital C, unpacks how a molecule once used only for industrial purposes is now making headlines for extending life and optimizing health. If you're curious about simple ways to boost your energy, sleep better, and feel younger, you'll want to hear how this overlooked discovery is changing lives. Listen to this episode and unlock your potential for a longer, healthier future! For show notes, visit https://fivejourneys.com/podcasts/how-you-could-live-longer-with-this-nobel-prize-winning-molecule/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes: Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun Longevity and mTOR: What the Science Says, with Dr. Robert Lufkin Live Longer & Reverse Aging, with Dr. Kara Fitzgerald Aging with Vitality and Strength, with Dr. Sandra Scheinbaum Reversing Aging: The Power of NAD+, with Dr. Nichola Conlon Hormones for Healthy Aging, with Dr. Daved Rosensweet Slow Aging by Optimizing These Redox Reactions, with Dr. Monisha Bhanote
What if everything you've been taught about nutrition is not just wrong, but actively harming your health? Cary Kelly's story might make you question your most basic assumptions about food and wellness.Cary grew up in a household religiously following conventional dietary guidelines—low-fat everything, margarine instead of butter, minimal red meat, and plenty of "heart-healthy" grains. Yet by his late 40s, his health was deteriorating rapidly. Chronic inflammation ravaged his body, extra weight accumulated around his middle, and simple activities became painful ordeals. When his arm suddenly went numb during a walk, Cary feared the worst.That frightening episode became his turning point. Desperate for solutions after being told he would simply have to "live with" his conditions, Cary reluctantly tried a new diet that seemed to contradict everything he'd been taught about nutrition. The results were nothing short of miraculous—within just three days, the inflammation that had plagued him for years began to subside. As Cary describes it, "It's like it had been raining inside my body every day for a decade and then, all of a sudden, the sun came out."Now, Cary has distilled his culinary expertise (from 28 years in the restaurant industry) into Carnicopia, a cookbook featuring simple, accessible meat-based recipes anyone can prepare. His approach isn't about perfection—it's about finding what works for your body and challenging the nutritional dogma that may be keeping you sick.Whether you're struggling with chronic inflammation, carrying extra weight that won't budge, or simply curious about why meat-based diets are transforming thousands of lives, Cary's story offers both inspiration and practical guidance. https://healthrecoverywithcarykelly.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
Holiday flights don't have to flatten your energy or your immune system. Dr. Robert Lufkin breaks down what actually happens to your body at altitude—lower oxygen, desert-dry cabins, stalled circulation—and shares a clear plan to stay sharp before, during, and after you fly. Instead of white-knuckling through recycled air and jet lag, you'll learn how to turn the cabin into a controllable environment and land clear, not crushed.We start with the physiology: why pressurization strains mitochondria, how dehydration slows immunity and brain function, and why hours of sitting leave lymph stuck. From there, we build a preflight foundation with real food, strategic fasting for domestic routes, and clean snacks for long-haul trips. You'll hear a practical mindset shift that reframes travel as rare, uninterrupted time for deep work, reading, or calm recovery—because the nervous system follows your plan.On board, we get tactical. Sip water every 15 to 20 minutes, stand and move each hour, and use nasal breathing to pump lymph. Block harsh blue cabin light to protect circadian rhythm, and skip alcohol to prevent immune drag and sleep disruption. After landing, lock in recovery with 10 minutes of outdoor light, legs up to drain swelling, a short movement session to clear inflammation, and continued hydration with electrolytes. We finish with a one-trip challenge that proves how fast these fundamentals work, plus invites to our quarterly three-day water fast, weekly newsletter, and trusted tools for proactive health.Ready to test the protocol and feel the difference on your next trip? Subscribe, share this with a frequent flyer you care about, and leave a quick review to help others land clear too.FASTING CHALLENGE: https://tinyurl.com/3feksfda Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
You may do intermittent fasting, optimize your diet, take your supplements, and prioritize sleep. But there's one powerful longevity tool that almost no one in the wellness space is talking about. What if the secret to living longer, reducing inflammation, and protecting your heart wasn't in a bottle or a biohack, but something your body already knows how to do? In this episode, Dr. Diane Mueller, a board-certified sexologist with dual doctorates in naturopathic medicine and acupuncture, reveals the surprising science behind how orgasms can add years to your life. Dr. Mueller explains how oxytocin (the hormone released during orgasm and cuddling) protects your cardiovascular system, resets your stress response, and reduces inflammation. If you're looking for evidence-based strategies to enhance your longevity while also improving your relationships and quality of life, this conversation will change how you think about pleasure and health. Listen now to start prioritizing pleasure for longevity! For show notes, visit https://fivejourneys.com/podcasts/how-orgasms-could-add-years-to-your-life/ Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes Reignite Intimacy And Sex Through Curiosity, with Dr. Elliot Kronenfeld Spice Up Your Lovemaking, with Susan Bratton Live Longer & Reverse Aging, with Dr. Kara Fitzgerald Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun Longevity and mTOR: What the Science Says, with Dr. Robert Lufkin Aging with Vitality and Strength, with Dr. Sandra Scheinbaum Reversing Aging: The Power of NAD+, with Dr. Nichola Conlon Hormones for Healthy Aging, with Dr. Daved Rosensweet Slow Aging by Optimizing These Redox Reactions, with Dr. Monisha Bhanote
STRONGER BONES LIFESTYLE: REVERSING THE COURSE OF OSTEOPOROSIS NATURALLY
Could fasting be one of the most overlooked tools for improving bone health, supporting osteoporosis and osteopenia, and strengthening your metabolism? In this episode, functional bone health expert Debi Robinson sits down with Registered Dietitian Ashley Bizzell to explore how intermittent fasting and autophagy support not only metabolic healing but also healthier, stronger bones.Ashley shares her path from traditional nutrition roles to functional metabolic medicine, where she now helps women reduce inflammation, balance hormones, improve insulin sensitivity, and support healthier aging.Together, Debi and Ashley break down how fasting influences bone density, why cellular renewal is essential for osteoporosis and osteopenia, and how women can safely integrate fasting into a bone-supportive lifestyle.They also dive into the Fasting Mimicking Diet developed by Dr. Valter Longo, explaining how it offers the benefits of fasting without full deprivation while supporting energy, gut health, and bone strength.What You'll LearnThe difference between fasting, starvation, and metabolic healing for women with osteoporosis or osteopeniaHow fasting activates autophagy and supports cellular repair that strengthens bonesThe connection between metabolism, insulin resistance, inflammation, and bone lossWhy hormonal balance is essential for maintaining and improving bone densityHow the Fasting Mimicking Diet (FMD) works and why it can be a safe strategy for bone healthThe role of hydration, nutrient density, and gut health during fasting for optimal bone supportAction StepsStart small: Begin with a gentle 12–14 hour overnight fast to support metabolic repair and bone renewal.Focus on hydration: Keep water and herbal teas flowing to support your metabolism, gut, and bones.Nourish wisely: Choose whole, nutrient-dense foods with plenty of healthy fats and minerals your bones need.Support your gut: A healthy microbiome improves nutrient absorption and helps strengthen bones from the inside out.Explore FMD: Consider guided fasting options like the Fasting Mimicking Diet to support cellular health and bone density.Resources & LinksLearn about the Fasting Mimicking Diet (ProLon) → prolonlife.comExplore Elra Health and L-Nutra Health → lnutrahealth.comListen to more episodes → Stronger Bones Lifestyle PodcastBuild strength from within → Healthy Gut, Healthy Bones ProgramFollow Debi on Instagram → @debi_robinson_yogaDebi's TakeawayTrue healing is built on rhythm, rest, and renewal — not restriction. When we give our bodies space to clean, repair, and rebalance, we support the metabolic and hormonal foundations needed for stronger bones and better aging. Start slow, listen to your body, and let gentle fasting become a supportive tool in your osteoporosis or osteopenia healing journey.
Cravings aren't just about weak will; they're biology doing exactly what billions of food dollars engineered them to do. We sit down with Sander Brus to unpack how sweetness hijacks reward circuits, why kids are showing up with adult metabolic diseases, and what happens when you flip the switch on sweet taste itself.Sander takes us from his diagnostics background into the heart of metabolic health, explaining how sweet taste receptors (T1R2/T1R3) live on the tongue and in the gut, where they act as glucose sensors. You'll hear how plant compounds like gymnemic acids can temporarily block those receptors, making soda taste like “nothing,” softening the dopamine surge, and even reducing post-meal glucose and insulin in some studies. We compare the behavioral punch of reducing perceived sweetness to the pharmacology of GLP‑1 agonists, and we dig into CGM experiments that show real-world spikes shrinking when sweetness is inhibited.We also zoom out to the food environment: why sugar is uniquely craved compared to seed oils or grains, how high fructose corn syrup supercharges palatability, and why noncaloric sweeteners may still nudge insulin through cephalic responses. Sander shares practical playbooks for using a mouth rinse to tame dessert triggers or a capsule 30 minutes before carb-heavy meals to blunt spikes. Along the way, we talk palate reset in 10–14 days, metabolic flexibility, insulin's role in aging pathways like mTOR, and the hope of nudging an industry to build foods that support healthspan rather than erode it.If you've ever wanted fewer cravings, steadier energy, and data-backed ways to quiet the glucose roller coaster, this conversation offers both science and tactics you can try today. Listen, share with someone navigating sugar struggles, and tell us your biggest craving scenario so we can tackle it in a future episode. And if you're finding value here, subscribe, leave a review, and help more people discover metabolic tools that actually work.https://nosuhealth.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
What if the real action in cancer isn't in the genome, but upstream in the mitochondria and the metabolic “terrain” that shapes every signal your cells send and receive? We sit down with Dr Nasha Winters to rethink cancer as an ecologic disease and explore how shifting the terrain can change outcomes without rejecting standard care.We dig into why ketones are more than fuel. Nasha explains how a therapeutic ketotic state—reached through fasting, carb restriction, or exogenous support—can lower inflammatory cytokines, dial down insulin and IGF-1, reduce angiogenic drive, and directly influence the vagus nerve to move the body into a healing state. You'll hear practical ways to pair ketosis with radiation, hyperbaric oxygen, and hyperthermia to both enhance efficacy and protect healthy tissue, plus real markers to track progress, from GKI and CRP to LDH and organic acids.Skeptical about “alternative” claims? So is Nasha—until the data line up. We talk pharmacogenomics, validated drug-sensitivity testing, and the smart use of repurposed meds like metformin, low-dose naltrexone, and mebendazole when the biology says they fit. We also connect longevity and cancer prevention through mitochondrial health: strategic fasting, urolithin A, melatonin, vitamin D, circadian repair, and toxin reduction all play a role in building metabolic flexibility. To close, Nasha unveils her vision for a residential, integrative hospital and research institute on a regenerative farm, where tumor experts and terrain experts co-manage under one roof—data first, dogma last.If this conversation expanded your map of what's possible in oncology and longevity, follow the show, share it with someone who needs options, and leave a review with the biggest insight you're taking into your own care.https://drnasha.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
Imagine your brain as a world-building engine that never shows you the thing-in-itself, only a model tuned for survival. Now imagine a molecule that doesn't just bend that model but switches it to a fully formed, hyper-detailed reality populated by entities that seem to think, act, and sometimes deny you entry. That's the claim at the heart of our conversation with computational neurobiologist and DMT researcher Andrew Gallimore, author of Death by Astonishment.We start by laying the groundwork: predictive brains, interface theory, and why ordinary dreams and hallucinations reuse what the brain already knows. From there we compare classic psychedelics—LSD, psilocybin, mescaline—with DMT. The former loosen constraints; the latter appears to replace the entire world model. Reports converge on crystalline clarity, higher-dimensional geometry, and interactive beings that feel autonomous. Andrew introduces the “lockout” effect, where access can be refused, and argues that orthodox neuroscience struggles to explain structured, agent-like phenomena arising so quickly and coherently.The breakthrough comes with extended-state DMT using target-controlled infusion—a medical technique borrowed from anesthesia—to hold explorers in the space for 30 to 90 minutes or longer. Early pilots suggest the state stabilizes, enabling intentional interaction and systematic observation. We explore a research roadmap: send in mathematicians to probe topology, linguists to parse symbolism, anthropologists to map social rules, artists to render lawful structure. Instead of asking entities to prove themselves, we let experts recognize operations that exceed typical human cognition, like effortless four-color theorem tilings or impossible geometric transforms performed in real time.We also talk safety, differences between DMT, ayahuasca, and 5-MeO, and emerging retreat-and-research models that combine medical oversight with rigorous protocols. Whether DMT reveals autonomous minds, emergent intelligence, or a yet-unknown information source, extended-state studies could convert private revelation into public evidence. Subscribe, share with a curious friend, and leave a review with the question you'd ask if you had an hour in the DMT space. What test would convince you that contact is real?https://noonautics.org/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...
In this bonus episode, Dr. Kahn sits down with Dr. William Hsu, Chief Medical Officer at L-Nutra (Prolon) and former Harvard Medical School faculty member, for a fascinating look at how fasting can help put Type 2 diabetes into remission. Dr. Hsu explains why muscle mass is crucial for managing diabetes — it's where glucose gets absorbed — and how the Fasting Mimicking Diet (just five days a month for six or more months) can lead to incredible results. The program not only supports blood sugar control but also helps preserve muscle and target belly fat, which is exactly what you want from healthy weight loss. Check out the programs mentioned in the episode:
A facelift without a telltale ear scar sounds like sci‑fi—until you hear how Dr. Mark Mani designed it. We sit down with the Beverly Hills surgeon, artist, and inventor to explore how endoscopic deep‑plane lifting repositions the face where gravity actually acts, delivering natural contour without the stigma of visible incisions. Mark traces the decade it took to refine the approach, publish the first academic description, and train surgeons worldwide, and he explains why subtle, anatomically honest work beats skin‑tension shortcuts every time.That precision sits inside a larger philosophy. Mark's childhood bridged Indian and American worlds, his studies spanned Harvard to Baylor, and his curiosity leaps from quantum theory to biology. He argues that humans cooperate far beyond what selfish‑gene logic predicts because we chase legacy—phenotypic immortality—through service, craft, and knowledge. That belief shows up in his operating room and his volunteer work with Face Forward International, where reconstructive surgery helps survivors of burns and abuse reclaim identity and voice. Beauty, in this frame, is not an algorithm; it's dignity, agency, and the confidence to meet another person's gaze.We also challenge a big myth: you can fill your way to youth. Mark makes the case for conservative strategy, fat over filler when volume is needed, and why overfilling often makes faces look bigger, not younger. Then we shift to recovery and daily life with the Mani Flow, his travel‑ready neck wearable that supports back sleeping, protects facial ligaments, and turns red‑eyes into real rest. If you care about natural results, subtle scars (or none), and the future of endoscopic facelifts, you'll find clear takeaways, practical nuance, and a humane way to think about aging and aesthetics.If this conversation sparked ideas, follow and share the show, leave a quick review, and tell us: what's one mindset shift that changed how you see aging?https://marcmani.com/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkinMimio Health (LUFKIN for 15% off) https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
A world champion athlete shouldn't have to fight for the right diagnosis—yet Kelly Palace did, for years. What began as a swimmer's quick fix for itchy, chlorine-dry skin became a descent into topical steroid addiction and withdrawal: spreading rashes, burning, oozing skin, misdiagnoses, and the long, lonely road of recovery. Kelly lays out the unvarnished truth about a “miracle cream” millions use and why the industry's strongest selling points—fast relief and flawless skin—can mask a deeper problem that grows with every tube and refill.We walk through the real mechanism under the surface: the blanching test that validated potency, the escalation from mild to super-potent products, and tachyphylaxis that drives dependency. Kelly explains how withdrawal can look nothing like classic eczema, why infants and facial skin absorb more, and how short, tightly defined courses can be appropriate for acute flares—while chronic use becomes a trap. Her journey to Dr. Marvin Rappaport's work, the co-founding of ITSAN (International Topical Steroid Awareness Network), and the movement to push medicine to recognize topical steroid withdrawal provide a roadmap for patients seeking answers when standard care fails.This is also a practical guide. You'll hear the questions to ask before filling a prescription, the difference between treating symptoms and addressing root causes, and the lifestyle foundations—sleep, hydration, nutrition, stress reduction, gentle barrier care—that help the skin do its job. Kelly makes a compelling case to treat the skin like the longevity organ it is and to choose what you apply as carefully as what you eat. The human side matters too: the isolation, the mental health toll, and the hope that comes with recognizing the pattern and finding support.If you or someone you love uses hydrocortisone, triamcinolone, or other topical steroids, this conversation will change how you think about risk, duration, and informed consent. Subscribe, share this episode with a friend or clinician who needs to hear it, and leave a review with your questions—what would you ask your doctor about your skin routine?https://www.kellypalace.com/ https://www.itsan.org/Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkinMimio Health (LUFKIN for 15% off) https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
What is a Fasting Mimicking Diet?_The TrulyFit Podcast welcomes Renee Fitton, RD. She is a Longevity Dietitian and Vice President of B2B Sales & Growth at L-Nutra (makers of ProLon® and L-Nutra Health). In this episode, she and Steve discuss:_-Fasting vs Fasting Mimicking-Longevity Misunderstood-Tips to ease into fasting-Prolon process-L Nutra-Gatekeeping Diet Info...much more_Learn more about her here:IG: @fittonnutritionL-Nutra: https://l-nutra.comProlon: https://prolonfmd.com_#fasting #nutrition #healthpodcast #trulyfitpodcast #fittonnutrition #prolon #lnutra #wellness #stevewashuta
What if you could enjoy all the powerful health benefits of fasting without actually going hungry? Dr. Chris Rhodes, a biochemist with a PhD from UC Davis, has discovered a revolutionary approach that might make this possible.During this fascinating conversation, Dr. Rhodes explains how fasting triggers a remarkable survival response in our cells. After about 24 hours without food, our bodies deplete glycogen stores and enter "true fasting metabolism," activating anti-inflammatory pathways, cellular cleanup mechanisms, and metabolic efficiency programs that can extend lifespan in virtually every organism studied.The breakthrough came when Dr. Rhodes identified four specific metabolites that appear in human blood during a 36-hour fast. When combined and given to C. elegans worms, these compounds extended their lifespan by a staggering 96% - essentially doubling how long they lived.This led to the creation of Mimio Health, a company developing supplements that recreate the molecular environment of fasting. Clinical studies show these supplements can maintain an anti-inflammatory state and cardioprotective benefits even while eating regular meals. Even more remarkably, eight weeks of supplementation reduced biological age by 2.5 years, increased free testosterone by 50%, and improved cholesterol profiles and glucose regulation. I am an advisor to Mimio Health, but I only work with companies that are based on solid science with a strong potential to help humanity.Throughout our conversation, Dr. Rhodes offers thought-provoking insights about how modern eating patterns create chronic inflammation and how our bodies evolved with natural fasting cycles. He argues that constant eating without fasting windows may actually be the unnatural state for human metabolism - not the other way around.Whether you're interested in longevity, metabolic health, or simply understanding how our bodies respond to food, this episode offers a compelling look at cutting-edge nutritional biochemistry that could change how we approach health optimization. Ready to discover how your body might already possess the blueprint for extraordinary health and longevity? Listen now and learn how to activate it.Mimio Health (LUFKIN for 15% off) https://mimiohealth.sjv.io/c/5810114/2745519/30611Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkinMimio Health (LUFKIN for 15% off) https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...
This week, Dr. Kahn reports on a new Mayo Clinic study on the relationship between chronic insomnia and accelerated brain aging in a group of study subjects who had advanced brain testing over time. He suggests 20 tips for better sleep and a bonus 21st: cognitive behavioral therapy for insomnia (CBT-I). Additional topics include heart disease remaining the #1 cause of death, TMAO and cognitive impairment, ATTR-cardiomyopathy, childhood blood pressure and future heart disease, niacin and optimal liver health, and the relationship between heart diseases like atrial fibrillation and cognitive decline. Thanks to igennus.com and the discount code DrKahn. Dr. Kahn will be leading a group Fasting Mimicking Diet starting 10/5/25. Order your PROLON kit (Next Gen) at www.prolonlife.com/drkahn.
This week, Dr. Kahn breaks down the latest guidelines for preventing and treating high blood pressure. He reviews the top 10 lessons from an important new medical article and encourages every listener to own a home blood pressure cuff, use it regularly, and aim for readings under 120/80. Along the way, he also discusses new research on Lipoprotein(a) myths, EMF exposure, cystatin C kidney lab tests, the Fasting Mimicking Diet and its impact on kidney health (prolonlife.com/drkahn), and the role of vitamin C in overall wellness. Thanks to igennus.com for supporting the show, with a special discount available using the code DrKahn.