Podcasts about recce

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Play Episode Listen Later Feb 18, 2025 10:02

Recce Pharmaceuticals Ltd (ASX:RCE, FSE: R9Q) director & chief medical advisor Dr Alan Dunton and executive chairman Dr John Prendergast talked with Proactive's Tylah Tully about the company's latest Phase 2 clinical trial results for RECCE® 327, a topical gel targeting Diabetic Foot Infections (DFIs) and Acute Bacterial Skin and Skin Structure Infections (ABSSSI). Dr Dunton explained that the Phase 2 study was conducted across three sites in Australia, testing the gel in 30 patients. The results showed a 93% cure or improvement rate after two weeks of treatment, with 82% of patients responding positively within the first week. He highlighted the gel's strong efficacy, noting that unlike many antibiotics, R327G did not develop bacterial resistance. Dr Prendergast emphasised that these findings provided confidence as Recce moved toward regulatory approval. He revealed that the upcoming registration Phase 3 trial in Indonesia, originally planned for 300 patients, may achieve meaningful interim data in as few as 100 patients. This could fast-track approval within a shorter timeframe, potentially 12 months. Both executives underscored the clinical potential of R327G, particularly in tackling antibiotic-resistant infections. With its first-in-class synthetic antibiotic properties, the gel could become a game-changer in infection treatment. #ReccePharmaceuticals #ASXRCE #Biotech #ClinicalTrials #Recce327 #Antibiotics #DiabeticFootUlcer #ABSSSI #DrugDevelopment #MedicalResearch #StockMarket

Just the Facts: Recce Pharmaceuticals scores 93% efficacy in Phase II trial

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Play Episode Listen Later Feb 17, 2025 2:08

Recce Pharmaceuticals Ltd has received positive Phase II clinical trial results for RECCE® 327 Topical Gel (R327G) in treating Acute Bacterial Skin and Skin Structure Infections (ABSSSI), including Diabetic Foot Infections (DFI). The study achieved a 93% primary efficacy endpoint over 14 days, with an interim response rate of 86% at seven days. No serious adverse events were reported. These results support Recce's upcoming Phase III registrational study for DFI in Indonesia, which has been approved by the Indonesian Drug and Food Regulatory Authority. An interim analysis is expected in 2025, with full trial completion anticipated by the end of the year. Recce will also advance to a Phase III trial for ABSSSI and DFI in Australia. Recce aims for an accelerated commercialisation pathway by 2026. The global ABSSSI treatment market was valued at US$7.3 billion in 2018 and is projected to reach US$26 billion by 2032. The trial followed FDA standards, using recognised diagnostic tools to assess treatment efficacy. The findings reinforce R327G's potential as a broad-spectrum anti-infective to address antimicrobial resistance. #ReccePharmaceuticals, #ClinicalTrials, #Phase2Trial, #Antibiotics, #AntimicrobialResistance, #SkinInfections, #DiabeticFootInfections, #MedicalResearch, #Pharmaceuticals, #Healthcare, #DrugDevelopment, #FDAApproval, #Biotech, #MedicalInnovation, #WoundCare, #R327G, #BacterialInfections, #PharmaIndustry, #AustraliaHealthcare, #GlobalHealth

De Beer: Cyril & John; Pieter & Corné; Cabinet “criminals”; valour “stolen” by MKP & SANDF General; Kagame's “war” talk

BizNews Radio

Play Episode Listen Later Feb 2, 2025 39:16

In this edition of the Sunday Show, the President of the United Independent Movement (UIM) Neil de Beer talks about the future of the Government of National Unity (GNU) being reset by President Cyril Ramaphosa and Democratic Alliance (DA) leader John Steenhuisen over a private lunch; the apparent disunity between Freedom Front Plus Leader Pieter Groenewald and Western Cape Leader Corné Mulder as yet another DA Mayor is ousted. De Beer lists the Cabinet Ministers and Deputies who are governing under a cloud; and slams former President Jacob Zuma's MKP appropriating the Umkhonto we Sizwe (MK) name, and SANDF Chief General Rudzani Maphwanya wearing honorary Recce and 44 Parachute Battalion badges. (He calls it “stolen valour”, and challenges the general to a tandem parachute jump). De Beer comments on the diplomatic row between Rwandan President Paul Kagame and “our limping, gutless president” - and lays into Defence Minister Angie Motshekga. He expresses concern about attacks on the highly efficient KZN Provincial Police Commissioner Nhlanhla Mkhwanazi. And, of course, he has a pointed message for ESKOM after the unexpected load shedding this weekend.

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Just the Facts: Recce Pharmaceuticals completes dosing in RECCE® 327 Phase 2 trial

Play Episode Listen Later Jan 21, 2025 1:28

Proactive's Tylah Tully breaks down ‘Just the Facts' of the latest news from Recce Pharmaceuticals Ltd (ASX:RCEOTC:RECEF). Recce has completed dosing for all 30 participants in its Phase II clinical trial of RECCE® 327 Topical Gel (R327G). This trial focused on treating Acute Bacterial Skin and Skin Structure Infections (ABSSSI). Conducted as an open-label study, it evaluated the safety, tolerability, pharmacokinetics and efficacy of R327G, applied daily over either seven or 14 days. Preliminary results indicated complete cures or significant symptom improvement in participants, with no serious adverse events reported. The full trial results are expected in the first quarter of this year. R327G is a synthetic anti-infective designed to address antibiotic-resistant infections. The company highlighted its strong safety profile and efficacy, particularly in patients with highly resistant bacterial infections. Recce plans to utilise the data to support regulatory submissions to the US Food and Drug Administration (FDA) and the Therapeutic Goods Administration (TGA). A Phase III trial is scheduled to begin in Australia during the first half of this year. #ProactiveInvestors #ReccePharmaceuticals, #ASX #ClinicalTrials, #Phase2Trial, #RECCE327, #TopicalGel, #ABSSSI, #AntibioticResistance, #SyntheticAntiInfective, #PharmaceuticalInnovation, #PatientSafety, #Efficacy, #FDAApproval, #TGAApproval, #DrugDevelopment, #HealthcareAdvances, #InfectiousDisease, #Australia, #Phase3Trial, #Biotechnology, #MedicalResearch

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Healthcare outlook 2025: healthcare and biotech to regain investor focus

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Play Episode Listen Later Jan 15, 2025 6:17

The healthcare and biotech sectors are set to regain investor interest in 2024 due to long-term growth prospects, aided by structural drivers such as ageing populations and rising healthcare expenditure. Healthcare now contributes 10.2% of global GDP, with annual spending expected to reach $14 trillion by 2030. Previously overshadowed by technology, healthcare is now viewed as undervalued following small-cap underperformance last year. Anteris Technologies Global Corp (ASX:AVR, OTC:AMEUF) is advancing its DurAVR® Transcatheter Heart Valve to treat severe aortic stenosis, supported by an $88.8 million Nasdaq IPO to fund further development and clinical trials. Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) is focused on synthetic anti-infectives targeting antibiotic-resistant bacteria and viral infections. Its flagship candidate, RECCE® 327, has received approval for a Phase 3 trial in Indonesia for diabetic foot infections, opening commercial avenues in the ASEAN region. Tryptamine Therapeutics Ltd (ASX:TYP, OTC:TYPTF) develops psilocin-based treatments for neuropsychiatric disorders. Interim results from a Phase 2A trial show potential for addressing Irritable Bowel Syndrome. Orthocell Ltd (ASX:OCC, OTC:ORHHF) targets regenerative medicine, with approved products such as Remplir™ for nerve repair and Striate Plus™ for dental applications. The company aims to expand into the US and other global markets. Lumos Diagnostics Holdings Ltd (ASX:LDX, OTC:LDXHF) specialises in rapid diagnostic tests. Its products, FebriDx® and ViraDx™, have received FDA approval, with ongoing efforts to expand within women's health diagnostics. #HealthcareSector #Biotech #MedicalDevices #DrugDevelopment #RegenerativeMedicine #Diagnostics #BiotechInvesting #GlobalGDP #AorticStenosis #AntibioticResistance #Superbugs #PsilocybinResearch #ChronicPain #NerveRepair #DentalRegeneration #RapidDiagnostics #COVIDTesting #FluTesting #HealthcareInnovation #InvestorOutlook

Cast Album Cage Match: EVITA vs. Billy Recce FLASHBACK

The Original Cast

Play Episode Listen Later Dec 25, 2024 85:05

originally released: December 22, 2021 9 recordings enter. Only 1 can leave. And it shall leave a champion. This is CAST ALBUM CAGE MATCH! Composer/lyricist Billy Recce joins Patrick to find the best cast album of one of their favorite shows: Tim Rice & Andrew Lloyd Webber's EVITA! PLAY-IN ROUND - 1979 Disco Album v. 1996 Movie Soundtrack ROUND 1 - Studio Casts: 1976 Concept Album v. Play-In Round Winner - World Casts: 1980 Australian v. 1989 World Tour - West End Casts: 1978 v. 2006 - Broadway Casts: 1979 v. 2012 ROUND 2 - Studio Winner v. West End Winner - Broadway Winner v. World Winner ROUND 3: The FINALE!! Billy Recce Dot Com A Musical About Star Wars The Original Cast Merchandise at TeePublic.com DO YOU LIKE MOVIE MUSICALS? DO YOU LIKE SONDHEIM? Then you will love our PATREON podcast The Original Cast at the Movies because 2021 is all about Sondheim Movie Musicals!! This month it's the 2016 documentary about the making of Merrily We Roll Along entitled Best Worst Thing That Ever Could Have Happened with Kimberly Cooper Schmidt! Patreon • Twitter • Facebook • Email

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Recce Pharmaceuticals ready for Phase 3 trial for R327G in Indonesia

Play Episode Listen Later Dec 9, 2024 4:32

Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) CEO James Graham joins Proactive's Tylah Tully to discuss the approval the company has received from Indonesia's Drug and Food Regulatory Authority (Badan POM) for a registrational Phase 3 clinical trial of RECCE® 327 topical gel (R327G) for treating diabetic foot infections (DFIs). The trial will start in mid-December and represents a significant milestone for the company in the ASEAN region. It will be conducted as a double-blinded, placebo-controlled study, enrolling up to 300 patients, with results expected in late 2025 and potential commercialisation in 2026. The trial has support from Indonesian stakeholders, including the Ministry of Health and PT Etana Biotechnologies as well as the Australian Government. The project will cost approximately US$2 million, partially offset by Australia's 43.5% R&D rebate. This will be one of the largest DFI studies globally and the first in Indonesia, addressing urgent health challenges in a country with more than 19.5 million adults living with diabetes. In Australia, Recce plans to launch a Phase 3 trial of R327G in 2025, aligning with its ASEAN-focused strategy. These advancements bring Recce closer to commercialisation, with Graham acknowledging support from Australian and Indonesian authorities in expediting the process. #ProactiveInvestors #ReccePharmaceuticals, #ASX #OTC #ClinicalTrials, #DiabeticFootInfections, #R327G, #ASEANHealthcare, #MedicalInnovation, #Indonesia, #BadanPOM, #HealthcareAdvancement, #DiabetesTreatment, #NovelTherapies, #GlobalHealth, #AustralianPharma, #InfectiousDiseases, #DFITreatment, #RNDRebate, #RegulatoryApproval, #MedicalResearch, #HealthInnovation, #PharmaNews

Bosoorlog Eps 2: SW Fourie-Nog Dieper in die Spes Magte se Wêreld

Klipkouers Potgooi

Play Episode Listen Later Dec 2, 2024 68:00

'n Diepgaande Gesprek met Sersant-Majoor SW Fourie "Kom ons begin met 'n glasie whiskey," sê Sersant-Majoor SW Fourie, 'n veteraan van Suidwes-Afrika (nou Namibië). Sy bynaam "SW" het 'n interessante oorsprong - dit kom van sy voorletters én sy Windhoekse herkoms. "In Durban by die basis het Riem de Jager opgemerk dat Windhoek se registrasie SW was, en so het ek SW geword - 'n naam wat nou al 40 jaar lank bly steek." Fourie praat met trots oor sy tuisland: "Namibië is 'n veilige land, omtrent so groot soos Suid-Afrika, maar met net 2.5 miljoen mense. Ons skiet nog die misdadigers daar - onlangs was daar 'n bankroof in Windhoek waar vier van die vyf rowers doodgeskiet is. Die vyfde een... wel, daaroor bly ek liewer stil." DIE ONTSTAAN VAN DIE SPESIALE MAGTE Die verhaal begin in die middel-sewentigerjare. "Die wêreldmagte het besef hulle is blind vir wat op die slagveld gebeur," verduidelik Fourie. "Dit het gelei tot die vorming van ons spesiale magte - die sogenaamde '30 Dirty Dozen'." Die eenheid het aanvanklik nou saamgewerk met die Rhodesiërs. "Ons het baie by hulle geleer - hulle was al diep in die oorlog toe ons begin het. Hulle het die RLI (Rhodesian Light Infantry) gehad vir vuurmagoperasies, en natuurlik die bekende Selous Scouts." Met 'n laggie voeg hy by: "In Rhodesië het ons Boere-aksent ons altyd weggegee - ons kon nie behoorlik Engels praat nie!" SAMEWERKING MET DIE ISRAELI'S In 1978 het die Israeli's na Fort Doppies gekom. "Kokie de Toi, Wyna de Toi se broer, was ons kursusleier. Hy het gesê, 'Daardie klomp Jode wat daar staan kom kyk hoe ons dit doen.'" Fourie vertel hoe hulle hul normale roetine gedemonstreer het - 'n sewe- of agtman-span wat kontak maak, hardloop, tussen mekaar skiet, en vuur-en-beweging uitvoer. "Een van daardie generaals het na my rugsak geloop en probeer dit optel - die rugsak het hom amper omgetrek! Hulle het vir Kokie gesê as hulle manne dit in die woestyn moes doen, sou hulle mekaar doodskiet." DIE VIER PILARE VAN SPESIALE MAGTE Fourie verduidelik dat die spesiale magte in vier hoofrigtings ontwikkel het: Bosoorlogvoering: Die kern van hul operasies See-operasies: Die sogenaamde "one-night stands" waar hulle depots, spoorlyne en brûe moes opblaas Lugoperasies: 90% van hul ontplooiings was nagspronge Stedelike oorlogvoering: Later ontwikkel vir operasies in buitelandse stede "1 Recce het letterlik alles gedoen," sê hy. "Ons het stedelike, bos-, lug- en see-operasies uitgevoer. 4 Recce het later bygekom as ons aanvalsduikers en padverkenners - hulle het ons in vyandelike gebied afgelaai en weer kom haal." PLOFSTOF-SPESIALIS Een van Fourie se spesialiteite was plofstof-hantering. "Dit was die tweede hoogste betaalde pos in die weermag, net na vegvlieëniers." Hy vertel van sy tyd as student-plofstofontlonter by Techs: "Ek het 'n van gehad, presies soos die een wat ons in die weermag gebruik het, met al die toerusting om bomme te ontlont. As my soeker afgegaan het tydens 'n lesing, het ek net verdwyn - die dosente het nooit regtig geweet waarmee ek besig was nie." UNITA EN GESPESIALISEERDE OPLEIDING 'n Groot deel van hul werk was die opleiding van UNITA-magte. "UNITA was ons buffer teen SWAPO," verduidelik hy. "Ons verste operasie was 650km in Angola in, waar ons spoorlyne moes ontwrig om die vyand se bewegings na Cuito Cuanavale te stuit." Fourie vertel van die uitdagings in hul opleiding: "UNITA en RENAMO het dieselfde gewoonte gehad - sodra hulle kontak maak, skree hulle 'Outomaties!' en maak 'n magasyn in sekondes leeg. Dit het ons lank geneem om hulle te leer dat dit ondoeltreffend is. Ons het hulle geleer om liewer 'double tap' te gebruik - twee skote op 'n slag, akkuraat gemik." EVALUERING VAN DIE VERSKILLENDE MAGTE Met jare se ervaring gee Fourie sy eerlike evaluering: "Van al die magte waarteen ons geveg het, was SWAPO die beste. Hulle het in Rusland opleiding gekry, maar hul beste ervaring het gekom van gevegte teen die Boere - ons het akkuraat geskiet en goeie taktiek gehad. Die ANC was aan die onderpunt - swak opgelei. Net bokant hulle was die Kubane - ook baie swak." DIE KUBAANSE KWESSIE "Op die hoogtepunt van die oorlog was daar tussen 20,000 en 30,000 Kubane in Angola," vertel Fourie. Hy deel 'n merkwaardige moment uit die vredesonderhandelinge: "Tydens 'n gesprek met Pik Botha het 'n Kubaanse generaal gedreig dat hulle nog 10,000 man sou stuur. Pik se antwoord was treffend: 'Ons sal net nog 'n duisend Suid-Afrikaners stuur - julle het tot nou toe net teen 2,000 van ons geveg.'" CUITO CUANAVALE EN UNITA SE OPOFFERING By Cuito Cuanavale het UNITA 'n kritieke rol gespeel. "Tussen ons gepantserde voertuie - die Olifant-tenks, Casspirs, Ratel 90's en Buffels - moes daar infanterie wees om die voertuie te beskerm teen RPG7-aanvalle. UNITA het daardie rol vervul. In daardie drie veldslae het meer as 2,000 UNITA-soldate gesterf."

Recce Pharmaceuticals secures Australian patent for synthetic anti-infectives

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Play Episode Listen Later Nov 27, 2024 3:49

Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) CEO James Graham joins Proactive's Tylah Tully to discuss the latest milestone of being granted an Australian patent for its synthetic anti-infectives, solidifying global patent protection for its key assets. The Patent Family 3 approval by the Australian Patent Office extends coverage of RECCE® 327 (R327) and RECCE® 529 (R529) until 2037. This completes Recce's intellectual property protection in major markets, including the US, Europe, China, Japan and others. The patent encompasses the manufacturing process for RECCE® anti-infectives, their use in treating infections and methods of administration, including oral, injectable, inhalable and transdermal applications. Graham noted that the milestone bolstered Recce's global position in addressing critical viral and bacterial threats with innovative therapies. The company's pipeline focuses on tackling antibiotic-resistant superbugs, with R327 and R435 targeting bacterial infections and R529 aimed at viral infections. Recognised by the WHO for its innovative approach, Recce has also received FDA designations for R327, providing 10 years of market exclusivity upon approval. The company's proprietary manufacturing capabilities support its clinical trials as it advances solutions for unmet medical needs. #ProactiveInvestors #ReccePharmaceuticals #ASX #AntiInfectives #AntibioticResistance #GlobalPatents #PharmaceuticalInnovation #R327 #R529 #Superbugs #NovelTherapies #WHORecognition #FDADesignation #Biotechnology #PharmaNews #AustralianPatent #InfectiousDiseases #SepsisTreatment #HealthcareInnovation #DrugDevelopment #GAINAct #GlobalHealth

Bosoorlog Eps 1: Die Recces: Binne die Wêreld van SA se Elite-eenheid

Klipkouers Potgooi

Play Episode Listen Later Nov 11, 2024 78:50

Die Pad na die Recces Wanneer jy die naam "Recce" hoor, dink jy dadelik aan Suid-Afrika se elite-soldate. Maar min mense weet werklik wat dit gevat het om een te word. Sersant-Majoor SW Forie en Sersant-Majoor James lig vandag die sluier. Die keuringsproses was berug - slegs 4 tot 6 uit elke 100 man het dit gemaak. Aanvanklik was dit 'n drie-week marteling waar kandidate 800 kilometer moes stap of hardloop - omtrent 42 kilometer per dag. Later het dit verander na 'n korter, maar dalk nog meer uitmergelende toets van vier-en-'n-half dae. "Die sielkundige aspek was die belangrikste," vertel Forie. "Kandidate het 'n 24-uur rantsoen-pak gedra, maar as jy daaraan geraak het, was jy dadelik gediskwalifiseer. Net water was toegelaat. Geen slaap nie. Dit was 'n toets van wilskrag, nie spiere nie." Die "Meellopers" - senior operateurs en sielkundiges - het elke kandidaat fyn dopgehou. Hulle het 14 verskillende eienskappe gesoek: spanwerk, leierskap, deursettingsvermoë, en die regte soort aggressie. Interessant genoeg was dit dikwels die kleiner, maer manne wat die beste gevaar het. 'n Ander Soort Leierskap Die Recces se benadering tot leierskap was revolusionêr vir daardie tyd. "Ons het nie geglo in die gewone weermag se rigiede hiërargie nie," verduidelik James. "By ons kon enige lid van die span 'n leier wees - offisier of nie." Voor operasies het spanne vir maande geoefen. Elke man het presies geweet wat sy rol was. As dinge skeef loop, het die spanleier almal se insette gevra. "Dit was 'n broederskap van vertroue," sê Forie. "Jou span was jou familie." Operasie Amazon: Die Nag wat Lobito Geskud Het Een van die mees dramatiese stories wat hulle deel, is van Operasie Amazon - 'n aanval op Lobito se hawekompleks in Angola. Die beplanning was perfek, die uitvoering foutloos. Die span het maande in Durban geoefen - strand-landings, stedelike oorlogvoering, spesiale wapenhantering. Hulle is met C-130 vliegtuie na die teiken gebied, toe oorgeskakel na Israeli Strike Crafts. Om radar te flous, het hulle stadig beweeg, die skepe ver uitmekaar om soos vissersbote te lyk. In die donker nag het hulle met Zodiac-bote die hawe binnegesluip. Drie-en-twintig massiewe brandstoftenks, 'n sementfabriek, en LPG-fasiliteite was die teikens. Wagte is stilgemaak. Motors en motorfietse het verbygery, 'n partytjie was aan die gang op 'n nabye woonstelblok se balkon. Maar niemand het die Recces gewaar nie. Toe die span veilig weg was, het die myne ontplof. Die naghemel het opgelig soos daglig. 'n Russiese skip in die hawe het gesink. Die brandstofvoorraad na Suid-Angola was lamgelê. Die Menslike Kant Maar selfs die gehardste soldate het 'n sagte kant. James vertel van sy besluit om te bedank - die lang tye weg van sy familie het swaar geword. Kommandant Andre Besbuier het sy bedankingsbrief voor hom opgeskeur en die volgende dag 'n alternatief aangebied: 'n pos by Doppies-basis waar hy nader aan sy gesin kon wees. "Dit wys jou die Recces was meer as net 'n eenheid," sê James. "Ons het omgegee vir mekaar. Ons het verstaan dat elke operateur 'n mens was met 'n familie, met 'n hart." Nalatenskap Die Recces se verhaal is een van buitengewone dapperheid, slim beplanning, en onbreekbare broederskap. Hulle het bewys dat ware krag nie net in spiere lê nie, maar in die verstand en die gees. En miskien belangriker - hulle het gewys dat selfs die gehardste vegters ook mans met harte kan wees.

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Recce Pharmaceuticals gains ethics approval for Phase 3 clinical trial in Indonesia

australia australian ethics phase indonesia results initial gains approval proactive indonesians clinical trials r d pharmaceuticals asean phase 3 phase ii dfis recce bpom

Play Episode Listen Later Nov 11, 2024 4:48

Recce Pharmaceuticals Ltd (ASX: RCE, FSE: R9Q) CEO James Graham joins Proactive's Tylah Tully to discuss the ethics approval the company has received for a Phase 3 Clinical Trial of RECCE® 327. Recce has received Human Research Ethics Committee approval has been received to begin dosing in Indonesia for a Registrational Phase 3 clinical trial for its RECCE® 327 (R327G) topical gel, designed to treat diabetic foot infections (DFIs). The large-scale, double-blinded, placebo-controlled trial, set to commence in mid-December, will involve up to 300 patients across Indonesia, with a 12-month study period. Results are anticipated by late 2025, with regulatory approval and commercial launch aimed for H1 2026. The trial, supported by the Australian and Indonesian governments and facilitated by PT Etana Biotechnologies, represents a critical step in bringing R327G to market. With an estimated cost of US$2 million, the trial will benefit from Australia's R&D rebate scheme, reducing financial strain. Approval from BPOM, Indonesia's food and drug authority, is expected soon. The trial capitalises on Indonesia's high diabetes prevalence and growing antimicrobial resistance needs. Approval in Indonesia could pave the way for further regulatory acceptance across ASEAN countries. Initial trials in Australia showed a 100% patient response rate, underscoring the potential of R327G to address severe infections in diabetic foot ulcers. Recce has also reported significant progress in its Phase II clinical trial for R327G to treat Acute Bacterial Skin and Skin Structure Infections (ABSSSI). With 20 of the 30 patients now dosed, the trial shows promising results, as all dosed patients have met the primary endpoints of either a cure or marked improvement without any Serious Adverse Events (SAEs) reported. The trial is set for completion by the end of 2024, reinforcing the potential of R327G in addressing critical unmet needs in bacterial infection treatment. The product's development trajectory is strengthened by previous regulatory endorsements and encouraging interim data, indicating a strong efficacy and safety profile. #ProactiveInvestors #ReccePharmaceuticals #ASX #DiabeticFootInfections #RECCE327 #Phase3Trial #EthicsApproval #Indonesia #ClinicalTrials #DiabetesTreatment #AntiInfective #HealthcareInnovation #Biotechnology #Diabetes #ASEAN #RDEntitlement #InfectionPrevention #MedicalResearch #DFI #TopicalGel #IndonesianHealth #BiotechIndustry

Recce Pharmaceuticals reaches midpoint in Phase II Trial for Topical Gel R327G

trial proactive reaches topical pharmaceuticals phase ii midpoint recce barwon health

Play Episode Listen Later Oct 9, 2024 3:25

Recce Pharmaceuticals Ltd (ASX:RCE, FSE:R9Q) CEO James Graham joins Proactive's Tylah Tully to discuss progress in a Phase II clinical trial for the topical gel RECCE® 327 (R327G). Recce has formally reached the halfway point, with 15 patients successfully dosed. The trial is assessing the efficacy of R327G against Acute Bacterial Skin and Skin Structure Infections (ABSSSI), including diabetic foot infections and other wound infections, which are areas of significant unmet medical need. Early data shows that R327G is well tolerated, with promising antibacterial effects observed across a range of infections. The trial aims to enrol 30 participants by the end of 2024. The clinical study locations have expanded, now including Barwon Health, Australian Clinical Research Network NSW and ACRN Melbourne, increasing access to this novel treatment. The global ABSSSI market was valued at US$1.34 billion in 2023 and is projected to grow to US$2.31 billion over the next decade. An interim clinical review is scheduled for mid-October 2024 with further results expected shortly thereafter. Graham expressed optimism about the trial's progress and the potential impact of R327G on the growing global healthcare need for effective treatments against drug-resistant bacterial infections. #ProactiveInvestors #ReccePharmaceuticals #ASX #R327G #Phase2Trial #ABSSSI #WoundInfections #DiabeticFootInfections #ClinicalTrial #AntibacterialGel #BroadSpectrumAntimicrobial #SkinInfections #DrugResistantBacteria #HealthcareInnovation #BarwonHealth #ClinicalResearch #Australia #InfectiousDiseases #BacterialInfections #MedicalResearch #Biotechnology #TGA #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

This Week on Broadway for September 1, 2024: Billy Recce

BroadwayRadio

Play Episode Listen Later Sep 1, 2024 67:06

Peter Filichia, James Marino, and Michael Portantiere talk with Billy Recce. Michael reviews Cats: The Jellicle Ball. Peter reviews Unentitled @ 59e59, The Bleeding Class @ 59e59, and Pretty Perfect Lies @ The Flea Theater. “This Week on Broadway” has been coming to you every week since 2009. It is read more The post This Week on Broadway for September 1, 2024: Billy Recce appeared first on BroadwayRadio.

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Season 6 Preview (S5 E9)

running weiss co creators yoni broadwayworld fowl play recce bway

Play Episode Listen Later Aug 29, 2024 1:16

The podcast is taking a little time off and will be back in the fall. Here's a preview of some of the topics that will be covered in season 6. Feel free to contact Captain Adam Orton with any comments or questions:armyconnect-connectionarmee@forces.gc.caConnect with the Canadian Army on social media:Facebook | X (Twitter) | Instagram | YouTubeVisit Forces.ca if you are considering a career in the Army.Copyright Information© His Majesty the King in Right of Canada, as represented by the Minister of National Defence, 2024

#82 Creating Fowl Play with Billy Recce and Yoni Weiss

Oh My Pod U Guys

Play Episode Listen Later Aug 12, 2024 55:45

U Guys, Co-Creators of the new off-broadway musical Fowl Play, Billy Recce and Yoni Weiss are here! This week we have a short and sweet BroadwayWorld Recap with all the hottest Bway news from BroadwayWorld.com! Then I am joined by creatives Yoni Weiss and Billy Recce to talk about their amazing careers, and their current off-broadway show, Fowl Play. Running for a limited engagement at the AMT Theater until August 17th, Fowl Play is a gay fantasia, following the journey of two down-and-out creatives who are commissioned to write an apology musical on behalf of a well-known conservative chicken company. Billy and Yoni share all about their creative process as co-creators and composer-lyricist for the piece. We also touch on their backgrounds as writers and directors, and how their individual paths crossed in the world of queer art. They are truly the best, U don't wanna miss this episode! Use code OHMYPOD for 20% off tickets at attendthefowlplay.com. Follow Billy on Instagram: @thebillyrecce Follow Yoni on Instagram: @yoniweissnyc Follow the pod on Instagram: @ohmypoduguys Learn more about your ad choices. Visit megaphone.fm/adchoices

Defence Research and Development Canada (S5 E6)

Play Episode Listen Later Jun 12, 2024 27:11

It's no secret that science drives innovation, and the same is true in warfare. Jean-François Morel is the Director General of R&D Science and Engineering at Defence Research and Development Canada (DRDC). It's a big title but a fitting one, because there's a whole lot of research happening, and he's the person keeping it all moving. Listen in to find out what DRDC is doing to help the Army stay ahead of the curve on the battlefield.Feel free to contact Captain Adam Orton with any comments or questions:armyconnect-connectionarmee@forces.gc.caConnect with the Canadian Army on social media:Facebook | X (Twitter) | Instagram | YouTubeVisit Forces.ca if you are considering a career in the Army.Copyright Information© His Majesty the King in Right of Canada, as represented by the Minister of National Defence, 2024

The Brigade Commander - Latvia (S5 E5)

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Play Episode Listen Later May 8, 2024 35:30 Transcription Available

Want to know what it takes to get things into gear for a big mission? Colonel Cédric Aspirault from 5 CMBG is preparing to be the first commander of the multinational Forward Land Forces Brigade in Latvia. He's working with our NATO allies to put the Brigade together and has a lot of thoughts on what is needed to complete the job.Feel free to contact Captain Adam Orton with any comments or questions:armyconnect-connectionarmee@forces.gc.caConnect with the Canadian Army on social media:Facebook | X (Twitter) | Instagram | YouTubeVisit Forces.ca if you are considering a career in the Army.Copyright Information© His Majesty the King in Right of Canada, as represented by the Minister of National Defence, 2024

205: Small Mindedness - The Mechanism of Control

REDACTED Culture Cast

Play Episode Listen Later May 1, 2024 28:55

Which is better? To Bug Out or to Harden Your Position?Which is better? Train in Recce or CQB?Which is better? A DMR or a MK18?Which is better? 9mm or 45acp?These questions represent different decision that go awry when we attempt to answer them at the wrong level of analysis. There is a strange hope that, if it were to come to brass tacks, the good men would do what is right. Yet conversations like those presented above are seemingly less concerned good men doing what is right, but instead, mere survival.Enjoy.This Episode has been sponsored by Obsidian Arms, a manufacturer of tools, parts and firearms, as well as operating as an OEM shop for those looking to bring excellence to the market. Their Minnesota-based shop builds and cuts parts out of U.S.-sourced materials. Their gunsmith tools, custom firearms, and capabilities can be found at www.obsidianarms.comFollow Obsidian Arms on Instagram at @obsidianarmsSupport the REDACTED Culture Cast at redactedculture.locals.comSSP and boutique products at redactedllc.comFollow us on Instagram at @redactedllcSupport the REDACTED Culture Cast at redactedculture.locals.comSSP and boutique products at redactedllc.comFollow us on Instagram at @redactedllc

Fighting Antibiotic Resistance: Going Public w James Graham

The Mentor with Mark Bouris

Play Episode Listen Later Apr 28, 2024 37:15

With Stake, Australia's leading investing platform, I'm excited to share the ninth episode of 'Going Public' - a new monthly series giving you unique access to the entrepreneurs, founders and executives who've taken their business public.This podcast will delve into the journey of James Graham, one of the youngest CEOs in Australia's public company sector. At 34, James leads Recce Pharmaceuticals (ASX:RCE), a rapidly growing medical technology firm taking on antibiotic resistance, a global health crisis.We explore the highs and lows of building a biotech company, the road to going public, and the impact of Recce's novel approach to fighting infectious diseases. Get insights into James' journey from startup entrepreneur to industry leader, his perspectives on global health, and his vision for making a lasting impact.In 2016, Recce was listed on the Australian Securities Exchange with the stock ticker RCE.DISCLAIMER:Views expressed are those of the individual only. This does not constitute financial advice. You can subscribe to the newsletter here: https://lnkd.in/e7C8akgj. Join the Facebook Group.Follow Mark Bouris on Instagram, LinkedIn & YouTube. See omnystudio.com/listener for privacy information. Hosted on Acast. See acast.com/privacy for more information.

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EP 64 Brian Cook & Clark Curnutt - BC Precision Ballistics, 6MM Max

Lone Element Podcast

Play Episode Listen Later Apr 15, 2024 88:33

This week we are joined by Brian Cook and Clark Curnutt from BC Precision Ballistics. They are the minds behinds the new 6MM Max cartridge, and if you're not familiar with it you've been living under a 6mm Arc rock. We cover everything from initial ideation to velocity testing and all the different payload options in between (Yes it defeats armor). We get schooled on what it takes to develop a cartridge that just may well dethrone 60+ years of NATO standards. This one is for the nerds. Links: https://www.instagram.com/bcpb6mmmax/https://bcprecisionballistics.com/

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- 122 - Pacific War - Operation Thursday, March 19-26, 1944

The Pacific War - week by week

Play Episode Listen Later Mar 19, 2024 45:26

Last time we spoke about the beginning of the Japanese counteroffensive on Bougainville, action on the Burma front and New Guinea. General Hyakutake was under immense pressure to dislodge the Americal force from Bougainville. He unleashed a grand counter offensive trying to break the American defensive lines. Both the Japanese and Americans began suffering heavy casualties, yet neither side wavered in its resolve. Over in the Burma front, the Galahad unit, aka Merrills marauders joined their British, American and Chinese allies in pushing the Japanese back. There were some issues involving friendly fire, but overall the allies were making gains in a theater where the Japanese had dominated for years. Over in New Guinea, the Japanese were continuing to retreat to Madang. Things were going so terribly, units were now being deployed to defend the western part of New Guinea. Japan was simply not winning the war of attrition. This episode is the Operation Thursday Welcome to the Pacific War Podcast Week by Week, I am your dutiful host Craig Watson. But, before we start I want to also remind you this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Perhaps you want to learn more about world war two? Kings and Generals have an assortment of episodes on world war two and much more so go give them a look over on Youtube. So please subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry for some more history related content, over on my channel, the Pacific War Channel you can find a few videos all the way from the Opium Wars of the 1800's until the end of the Pacific War in 1945. Things have really been heating up on the Burma front. General Mutaguchi basically tricked his own superiors into allowing him to invade India under the guise of Operations HA-GO and U-GO. This saw Japanese units advancing towards Imphal and Kohima. On the other side General Stilwell's forces were advancing upon Myitkyina in the north, as General Slim's 15th corp were clashing with the Japanese in the Arakan region. Americans, British, Indians, Chinese were all performing operations to halt Japanese attacks and push further into Burma, but on top of all of that, we now need to talk about our favorite child born from the onion eating madman Wingate, the Chindits. All the way back in early February, Operation Thursday was in development. The operation was basically an extended version of the first Chindit raid, this time in two waves, with 3 brigades making long marches across the Chindwin. The first wave would go into the enemy territory, then 2-3 months later the second wave would come in to reinforce them. There were large issues with the operation, namely a lack of aircraft. Aircraft were being used for the Arakan campaign and flying supplies over the Hump. Chiang Kai-shek would not part with any aircraft set to go over the Hump and not even Mountbatten had the authority to touch the issue. Regardless Thursday would be authorized and its goals were as follows; to assist Stilwell's advance; to create favorable conditions for the Y-Force to gord the Salween and to inflict maximum damage to the Japanese in northern Burma. Their principles targets were the Shwebo-Myitkyina railway and the Myitkyina-Bhamo-Indaw road. There would be 4 strongholds to be designated, Piccadilly, Chowringhee, Broadway and Templecombe, the last one later renamed Aberdeen. The US 900th airborne engineer company would clear strips suitable for Dakotas to land. On February 4th Wingate and Stratemeyer, commander of the Eastern Air command issued the essential guidelines for Thursday, stressing this raid would require the wounded being flown out from the strongholds rather than to be abandoned as was the case with the first expedition. Stratemeyer added orders to bomb the stronghold areas prior to their establishment, though Wingate had instead favored diversionary bombings of Rangoon, Mandalay and Bangkok. On February 5th of 1944, Fergussons 16th brigade kicked off first from Ledo and onlookers would remark they looked more like a mule train than a commando force. There were elephants, 250 bullocks, 547 horses and 31314 mules assigned to the operation. Fergusson's 4000 men took 500 mules, fully laden along with them. They avoided Japanese forces by traversing exceptionally difficult terrain. It would be a full month before all Brigade Battalions crossed the Chindwin river. The main target was Indaw, although two Columns were tasked to attack the town of Lonkin, in the Kachin Hills and 20 miles west of Kamaing. Two gliders, loaded with folding boats, outboard engines, and gasoline, were towed by air to the Chindwin River and softly set down on a sandbar. Not only were the necessities delivered to Fergusson, but also for reuse the pair of C-4As were plucked from the scene by a C-47. Wingate traveled with Fergusson and his men for the first the start of the grueling ascent up the Paktai. They faced mud slides, torrential rain, the usual Burma experiences. It would take them all of February to reach the Chindwin, after that it was another 200 miles to their target of Indaw. Wingate departed after the first few days, but would come back over by aircraft to observe the crossing of the Chindwin. Fergusson had been critical of Wingate in January, describing him as a liar, but he continued to believe in the man. “Wingate was sometimes wrong in small things but never in big.' When Wingate met Fergusson he showed up with an entourage of war correspondents, trying to publicize the Chindits activities. He began talking to them of a new fad he came across, turtle eggs which he declared provided singular nourishment. Like so many of Wingate's eccentric ideas, no one favored it. Turtles' eggs were found to be no more appetizing than those of any other reptile, and in fact many of the Chindits experienced stomach pains and other digestive problems after eating them. Then Fergusson had to tell Wingate they could not possibly reach Indaw earlier than March 20th. The expectation had been March 5th, thus Wingate was pissed. At the same time, the 1st air commando had performed aerial reconnaissance over the 3 selected locations suitable for bringing gliders, Broadway, Piccadilly and Chowringhee. Yet Wingate had issued strict orders banning any further overflights fearing it would give up their intentions to the Japanese. Despite the warning, Colonel Cochram dispatched a B-25 on March 5th to perform a final look over the sites, giving last minute reports that Broadway and Chowinghee were clear, but it looked like teak logs were sprawled over the Piccadilly site. Since the Piccadilly site seemed unsuitable, Brigadier Calvert persuaded Wingate to send the Gliders into Broadway. On the night of March 5th, the gliders carrying the second wave were flown in. The pathfinder gliders, first to touch down, set out flare pots to facilitate succeeding waves of gliders. However, the field proved far less accessible than expected. For many years, the local people had logged teak and during the wet season, slid the huge logs across the ground down to a river. Over time the technique gouged deep ruts that elephant grass covered, making the trenches invisible to aerial photographs or reconnaissance. Co-commander of the 1st air commando group John Richardson Alison recalled "They formed perfect glider traps, and there was no way to avoid them. The gliders arrived overhead in large numbers, and when a glider starts down there is no way to stop it. As each one hit the trenches the landing gears would come off and the gliders would go in a heap. We tried to arrange the lights to spread the gliders all over the field to avoid collisions, but this was impossible. They were coming in too fast to change directions, and glider after glider piled into each other while landing.” The next day the gliders landed successfully on Chowringhee and the airstrip was completed by nightfall. Meanwhile transports began to bring Calverts 77th brigade, followed by Brigadiers Lentaigne's 111th brigade. By the 11th, the fly in was complete, now 9250 Chindits were landed on Broadway and Chowringhee. The Chindits then began their advance east to hit the Lashio-Bahmo-Myitkyina motor supply line. Trekking from Chowringhee, Morris Force Columns headed north-east, to cut the Bhamo-Myitkyina road, as 111 Brigade's British Battalions marched south from Broadway to link up with other elements flown into Chowringhee. Their job was to stop Indaw being reinforced from the south. Thus, 111th Brigade set up ambushes and roadblocks south of Indaw although part of the brigade which landed at Chowringhee was delayed in crossing the Irrawaddy River, before moving west to Pinlebu. Broadway was held with a garrison that included field artillery, anti-aircraft guns and some six Spitfires that would successfully repel a Ki-43 attack on March 13. Meanwhile Calvert's columns advanced over the railway towards Henu, where they would establish the White City stronghold, roughly 20 miles north of Indaw. Columns were directed to demolish bridges and railroads around the Kadu, Mawhun and Pinwe stations. It was a long and gruesome march over some very tough terrain. For example, it took Column 45, bringing up the Brigade's rear, nine days to cover the first 35 miles, to Hkalak Ga. They set out again on February 22nd. By this time, the men were tiring of K-rations, which gave calories but no bulk. Smoking was confined to lunch and evening bivouacs. The Leicesters were in the lead and reached the Chindwin on February 29th. Meanwhile, 45 Recce's columns, still in the rear, reached the Chindwin during the afternoon of Saturday March 4. It had taken them 21 days to cover some of the wildest, toughest country on earth. After successfully crossing the Chindwin, on March 12th Fergusson received orders to seize Indaw's airfield, destroy supply dumps in the area and establish a new Stronghold, to be known as Aberdeen. The Brigade continued south, moving parallel to and west of the railway. Meanwhile Calvert's 5 columns to 5 days to reach Henu. The South Staffords were the first to arrive and the Japanese reacted before they could dig in – they would have to fight for the Block. were on the alert to resist their incursion. In the afternoon of 16th, Calvert launched a bayonet charge up Pagoda Hill, with the Chindits soon engaging the Japanese engineers, who were charging down, in a vicious hand-to-hand combat. Eventually, with the assistance of the 1st Air Commando's close support, the Japanese were successfully pushed off the hill and the White City stronghold was established. For the loss of 23 dead and 64 wounded, Calvert's Chindits had killed 42 Japanese and had effectively cut the line of communications supporting the 18th Division far to the north. In the ensuing days, the stronghold would be developed into a fortress, with some airstrips becoming operational by March 21st. The time chosen to drop the Chindits near the 18th Division's line of communications was most embarrassing to General Tanaka. On January 10, Headquarters, 15th Army, had suspended movement of supplies to the 18th Division in order to accumulate stocks for the projected attack on Imphal. Shipment was to resume as soon as the Imphal operation was underway. Then the Chindits cut the rail line, and just when the supply movement was to have resumed, the 18th Division had to start living on what was at hand in north Burma. It was aided by the 56th Division, which shipped about ninety tons of vital supplies to Myitkyina via Bhamo, but Tanaka's supply position was fundamentally compromised by the Chindits fighting along the railway to north Burma. On the 18th Calvert's force took a large night drop, including wire and entrenching tools. They slaved away to turn the Block into a fortress. The parachutes festooned across the forest canopy gave the Block its popular name – White City – soon a maze of slit trenches and bunkers roofed with heavy timbers. White City, with its commanding position, became a powerful concentration of force, with Calvert's three Battalions steadily reinforced. The Block grew a heavily wired perimeter and a garrison strong enough to raise a substantial force for mobile action. Calvert regarded White City as “ideally situated around a series of hills about 30ft to 50ft high, with numerous small valleys in between, with water at the north and south. I brought the village of Henu into our defended area, so that we would have a good field of fire across the paddy to the south. I also brought into the perimeter what we called ‘OP Hill', a feature slightly higher than our own little hills, to give us good observation. Our perimeter was now about 1,000 yards long, mostly along the railway, and 800 yards deep.” Calvert now had 2,000 men inside the Block, with mobile “floater” columns operating to north and south, together with a sizeable force protecting Broadway. He called in air strikes to punish a Japanese force at nearby Mawlu. Meanwhile the 15th Army's staff were beginning to panic. Many of the officers were beginning to see the paint on the wall and were calling for the Imphal offensive to be abandoned. General Mutaguchi refused to give up and instead directed some troops to thwart the Chindits. To do this a reserve battalion was taken from the 15th, 18th, 33rd and 56th divisions and redirected to Indaw while Colonel Yanagisawa Hiroshi's 67th regiment moved over to Napin. Major General Hayashi Yoshihide's 24th independent mixed brigade was ordered to advance north along with some units of the 2nd division who would open a new HQ at Indaw by March 25th. Further behind the lines, the 53rd division led by Lieutenant-General Kono Etsujiro were directed to rush north to engage the enemy as fast as possible. All of this was still a diversion from the main effort against Imphal and it basically helped Stilwell's operations. To aid the war effort the IJA air force were also stepping up their game. On march 18th, a KI-43 raid managed to destroy some Spitfires grounded at broadway. William 'Babe' Whitamore and Alan M Peart managed to get airborne, with both shooting down one 'Oscar' each. Whitamore was shot down and killed but Peart survived for over half an hour, holding off over 20 enemy fighters. The remaining Spitfires were destroyed on the ground for the loss of another pilot, Lt Coulter. Peart flew back to Kangla the same day in his damaged Spitfire and reported the action. The following day, Fergusson's footsore columns finally neared Manhton village and prepared to establish the Aberdeen Stronghold. After an appalling final leg of their terrible march into Burma, with progress reduced at some points to 100 yards per hour, the 16th Brigade elements finally reached Aberdeen clearing, some 60 miles west of Broadway Stronghold. The Aberdeen clearing was at Manhton, just east of the Meza River and 25 miles from the railway supplying the Japanese 18th Division, fighting Stilwell's Chinese troops, and the 56th Division, opposing the Yunnan Chinese. Aberdeen took in three villages: Manhton, Kalat and Naunghmi. Aberdeen's site had a lot of advantages. It was only two days' march from Indaw and 14 miles from the Indaw-Banmauk road. The dominant feature was a hill at the northern end, where the permanent garrison would be quartered. There were, however, some drawbacks – mainly the fact that, as Fergusson himself acknowledged, it was “highly accessible” to the enemy. The 16th brigade were exhausted and needed rest, the planned attack against Indaw would have to be delayed. To the south, on the 21st the Japanese launched a major night attack against White City. The battle was ferocious, Calvert's Chindits managed to successfully repel numerous attacks for over 8 hours until the Japanese finally pulled back. The Japanese suffered an estimated 300 deaths, the Chindits also suffered heavy losses. In the White City perimeter, men took solace from the companionship of the animals sharing their hardships. A pony gave birth to a foal during a Japanese attack and murderous mortar barrage. The foal was named “Minnie” after a nearby mortar post. In another attack, Minnie was kicked in the eye by a panic-stricken mule. They fought to save the eye and Brigadier Mike Calvert ordered regular reports of Minnie's progress to be circulated to all forward positions. When recovered, Minnie took to “doing the rounds” of the mortar positions, on the scrounge for tea – which she drank from a pint pot. Minnie survived White City and further battles and went on to enjoy a distinguished military career as the Lancashire Fusiliers' mascot. Minnie got out to India, traveled to Britain and subsequently joined the Regiment on a tour of duty in Egypt. On the 23rd, leading elements of Brigadier Thomas Brodies 14th brigade began to arrive to Aberdeen with the task of blocking the Indaw-Banmauk road. At the same time, the 111th Brigade's columns were ordered to stop Japanese movements along the Pinlebu-Pinbon. The advance on Indaw may have been compromised inadvertently by the movements of 111 Brigade. One of its British Battalions, the Cameronian's, moved in a wide sweep west of Indaw, crossed the Banmauk road on the 22nd, with orders to cut the Indaw-Homalu road. They bumped into a Japanese patrol at night and their two wounded were flown out by light aircraft the next day. The men became hardened to the realities of jungle warfare against the Japanese, who fought to the death. Some columns were luckier than others regarding their supply drops. The King's Own columns had a reputation for being unlucky. During the 21-23, three successive attempts to re-supply them failed. Already, the columns were heavily reliant on food purchased in villages. Wingate then visited Bernard Fergusson at Aberdeen. Fergusson wanted to rest 16 Brigade after its exhausting march in but Wingate told him to press on to Indaw before it could be reinforced. Unfortunately, however, the Japanese had already accomplished this. The 16th brigade departed Aberdeen on the 24th, heading south to Auktaw, drawing closer to the heavily-reinforced Indaw. Between them were strongpoints at Thetkegyin village. This part of the country was quite dry and the Japanese controlled all the water sources, thus the Chindits would be forced to fight to drink. Despite successfully blocking the Indaw-Banmauk road, most of Fergussons columns would get sucked into heavy fighting around Thetkegyin on the 26th. Only the 2nd Leicester's columns 17 and 71 made it to Indaw, holding a toehold grimly until they were ordered to pull back. After 5 intense days of fighting, Fergusson ordered his men to withdraw and regroup at Aberdeen. Back on the 24th, Wingate flew down to Broadway and White City on a morale-boosting mission to 77 Brigade. After a side trip to Aberdeen, he flew back to Broadway and then on to Imphal. This would be the last time Calvert ever saw him. Wingate flew back to Imphal, landing at 6:23pm before taking off again at 8pm for Hailakandi airfield. Half an hour later the B-25 crashed into the Naga hills due west of Imphal near the village of Thilon. Cochran dispatched a special force to search for the crash and they found it the next day. Everyone inside the B-25 had died instantly. Investigators believed the crash could have occurred from freak weather, engine failure or pilot error. But since it was Wingate, there was an air of reluctance to accept it was just an accident. An official investigation concluded it had been the result of engine failure and that the pilot unsuccessfully tried to return to Imphal. Yet other theories emerged and were tested out. Sabotage was the first, but it was ruled out because the B-25 had been closely guarded at all times and nobody knew Wingates intentions or flight plans. Thunderstorms and turbulence were cited as plausible, but all pilots in the area confirmed no thunderstorms. General Slim opted for extreme turbulence, even though the pilots' testimony also ruled that out. ‘The wreckage was eventually found on the reverse side of a ridge, so that it was unlikely that the aircraft had flown into the hill. The most probable explanation is that it had suddenly entered one of those local storms of extreme turbulence so frequent in the area. These were difficult to avoid at night, and once in them an aeroplane might be flung out of control, or even have its wings torn off.' Another theory had it that the B-25's cluster bombs had broke loose from the bay's rolled into the fuselage and detonated. Given, well how Wingate was, many in the Indian army rejoiced at his death, some quoted Shakepears Macbeth ‘Nothing in his life became him like the leaving it.' Mountbatten wrote to his wife Edwina ‘I cannot tell you how much I am going to miss Wingate. Not only had we become close personal friends but he was such a fire-eater, and it was such a help to me having a man with a burning desire to fight. He was a pain in the neck to the generals over him, but I loved his wild enthusiasm and it will be difficult for me to try to inculcate it from above.' General Slim had this to write on Wingate “With him, contact had too often been collision, for few could meet so stark a character without being violently attracted or repelled. To most he was either prophet or adventurer. Very few could regard him dispassionately; nor did he care to be so regarded. I once likened him to Peter the Hermit preaching his Crusade. I am sure that many of the knights and princes that Peter so fierily exhorted did not like him very much – but they went crusading all the same. The trouble was, I think, that Wingate regarded himself as a prophet, and that always leads to a single-centredness that verges on fanaticism, with all his faults. Yet had he not done so, his leadership could not have been so dynamic, nor his personal magnetism so striking.” And so went Wingate, probably one of the most colorful characters of the Pacific War. In light of Wingates death, General Slim promoted Lentaigne to Major-General and appointed him the new commander of the 3rd Division. Slim, had loose operational control over Special Force, selected Brigadier Lentaigne to be Wingate's replacement after conferring with Brigadier Derek Tulloch, Wingate's Chief of Staff. Lentaigne was judged to be the most balanced and experienced commander in the force; he had been an instructor at the Staff College at Quetta, had led a Gurkha battalion with distinction during the grueling retreat from Burma in 1942 and had commanded a Chindit brigade in the field. As an officer of Gurkha troops, he had a similar outlook and background to Slim. The other Chindit brigade commanders were unknown quantities, mostly without staff qualifications, some of whom had never even commanded a battalion-sized unit in combat before 1944, and Wingate's staff officers lacked the necessary combat experience. The force's second-in-command, Major General George Symes, was bypassed by Slim and formally protested and asked to be relieved. In selecting Lentaigne, Slim did not take into account the tensions between those Chindit commanders and staff who were closely associated with Wingate, and Lentaigne, who had a classical "line" officer's background and had been critical of Wingate's methods and techniques. The loss of Wingate caused significant damage to the Chindits, it was as if they lost their persona. The month following Wingate's death, the 14th, 16th and 111th Brigades appeared to lack direction. They stayed around Indaw, ambushing the Japanese but with no major objective. As Slim, noted, "The immediate sense of loss that struck like a blow, even those who had differed most from him—and I was not one of these- was a measure of the impact he had made. He had stirred up everyone with whom he had come in contact. " At Broadway, for instance, after days of aerial attack, the 2nd Battalion, 146th Regiment stormed across the airstrip on March 27th and attacked its lightly defended western perimeter. Thankfully, the attack was repulsed, partly due to superior numbers. Three days of hard fighting at Broadway then ended with counterattacks and concentrated airstrikes finally dislodging the enemy. Though the Japanese regrouped, they were again pushed back by counterattacks supported by airstrikes in the end. Meanwhile, White City's defenses were strengthened. The Dakota brought over four 25 pounders, six Bofors anti-aircraft guns and four two-pounder anti-tank guns. This would allow Calvert to attack Mawlu on the 27th. As a result, the village was successfully taken and burnt out with flamethrowers, with the Chindits then reducing the remaining Japanese strongpoints. By the end of March, however, several major changes were made at the highest level. Much of the air support was diverted to the critical battles of Imphal and Kohima, where troops were cut off and could only be resupplied by air. The 23rd Brigade, yet to fly in, was also dispatched to Kohima. Finally, the Chindits were formally subordinated to General Stilwell, who ordered them to abandon their dispersed operations around Indaw and concentrate on interdicting the supply lines to the Japanese forces opposing his troops. In early April, while the 3rd West African Brigade and the remainder of Brodie's 14th Brigade were being brought in to Aberdeen, Lentaigne ordered the 111th Brigade led by Major John Masters to advance north and build the new Blackpool stronghold, which would block the railway and main road at Hopin. To Calvert's disgust, he was ordered to abandon White City and Broadway and move north to support the new stronghold, as Lentaigne insisted that the Chindit brigades were too far apart to support each other. But that is all for today in the Burma front as we now need to head over to Bougainville. The counterattack on Bougainville shifted on March 15th. General Kanda noticed Iwasa and Muda's Units were struggling to break through in their areas, so he changed the point of attack for the Magata Unit. He withdrew the bulk of the forces from Hills 700 and 260, sending them westward in preparation for a final attempt to break through towards the Piva airfields. The reserve 6th cavalry regiment was sent to reinforce Mugata's rear while the 2nd battalion, 4th South Seas Garrison was brought forward to try and contain the Americans at the Saua river mouth. Thus, there was a five-day break in the major action while the Japanese transferred the 13th and 23rd Regiments to reinforce what was left of Colonel Mugata's 45th Regiment. At this time the Japanese maintained patrols, which sometimes got into firefights with American patrols. A number of Japanese were taken prisoner during these patrol actions. From time to time the Japanese would lob mortar shells into the 129th's sector. During this lull in the fighting, the tired American riflemen and engineers were busy strengthening the defenses. Pillboxes were rebuilt, tactical wire reestablished, illuminating devices installed, communications improved, and the many Japanese dead buried. Information gained from prisoners and reconnaissance led General Beightler to conclude that the Japanese would launch a major assault on March 23rd. It was estimated that General Kanda had approximately 4850 men at his disposal to renew the attack on the 129th's front. Meanwhile the American artillery was smashing the South Knob who were now only being defended by a screening force. On the 18th, General McCulloch launched a final combined assault against the Knob. Companies A and B of the 132nd regiment performed a enveloping maneuver and enjoyed some initial success until they came upon heavy fire from Japanese bunkers. At 2:10pm the next day the attack resumed, this time successfully destroying several pillboxes, but the Americans were halted short of the crest. On the 20th, Company B was reinforced with a platoon from A and they circled the south end of the Knob, reaching the base of the trail going east. There they discovered the Japanese could pour down just as much fire, seeing another failed attack. Because of this failure it was decided to leave the reduction of Hill 260 to artillery and mortars. On the 23rd, the Iwasa and Muda units had completed their movement, now 4850 troops were concentrated on the northern sector ready to perform a major assault. Having been forewarned by the captured documents, the American forces were expecting the attack. The Americans unleashed a heavy artillery bombardment against Magata's assault forces as they were forming up, disrupting their initial advance and causing massive casualties. Late in the evening, Kanda launched his own assault, with General Iwara's 2nd battalion, 23rd regiment and 2nd battalion, 13th regiment through Cox Creek followed by Muda's men. Advancing under darkness, the Japanese surprised the Americans and managed to knock out 3 pillboxes under heavy fire. The area of attack was so narrow, artillery and air strikes could not be performed safely, so General Beightler ordered the 148th regiment to respond with a combined tank-infantry assault. With the support of Sherman's the Americans stormed the Japanese positions at 7:25am successfully reoccupying must of their lost territory within only 20 minutes. The Japanese tossed further attacked but were being gradually pushed from the narrow area by noon. During the afternoon, General Kreber's corp and divisional artillery began concentrating their fire on a very narrow sector where the bulk of the surviving Japanese were dug in. An infantryman of the 129th recalled: “All these big guns opened fire into this area about 500 yards in front of us, and I remember what they called a million dollar barrage and it's something you never forget–the big guns shooting over your head. It was very frightening because you wondered whether one of these shells would not go far enough. It was all jungle out in front of us and when they got done it was all cleared out. They had knocked everything down. A lot of Japs were killed by this… I can remember the day after the big attack the bulldozers came in and dug these huge trenches and we had to go out and take the Japanese and drag them into these. Because of the warm weather they began to smell pretty bad. Many, many killed!” It was the heaviest artillery concentration seen as of yet during the Pacific War. It completely disrupted the Magata unit, causing tremendous casualties. The 2nd Battalion, 45th Regiment were completely disorganized; the 1st and 3rd Battalions were reduced to 20 men; the 1st Battalion, 81st Regiment were reduced to 40 men; and the 3rd Battalion, 53rd Regiment were down to 100 men. The massive losses forced the Japanese to withdraw. General Hyakutake now realized his counteroffensive was a failure and forced to call it off. The Japanese were in full retreat by the 28th. The Magata force, with an estimated strength of over fifteen hundred men, utilized the Numa Numa Trail and withdrew toward the northern part of Bougainville. The remnants of the Iwasa and Muda forces, covered by reinforcements from the 4th South Seas Garrison unit and the 6th Cavalry Regiment, moved quickly along a number of trails to the relative safety of southern Bougainville. The units of the 17th Infantry Group returned to northern Bougainville and rejoined its parent unit. On the 28th, the 182nd regiment found the South Knob abandoned and finally secured Hill 260. The three-week battle for the rather insignificant knoll had cost the Americans 98 deaths and 581 wounded, counting 560 dead Japanese on the knob. Total casualties for the final Japanese counteroffensive on Bougainville would be 263 American dead and over 2489 Japanese bodies counted. In reality, Hyakutake's 17th Army lost a total of 3000 killed and 4000 wounded in their March operations, including 2398 killed and 3060 wounded from the 6th Division. General Beightler expressed the feelings of many in stating that the beating administered to the 6th Division was a partial repayment for its role in the rape of Nanking in 1937. Although the Japanese would plan another concentrated assault on Allied positions later down the line, they would never again launch a major attack. For all practical purposes, the battle for the Solomons was now over. Now we need to jump over to the Southwest Pacific. As a result of the Admiralty Islands being invaded a month ahead of schedule. Yet General MacArthur kept his gaze on the development in the Central Pacific. He needed to pick up the pace if he wanted to win the race, so he planned to carry out the invasion of Kavieng, bypassing the Hansa Bay area with a direct jump to Holland before the end of April. General Sutherland gave the Joint Chiefs an outline calling for the Southwest Pacific forces to move into the Hollandia area with two divisions on April 15, supported by the Pacific Fleet. Air, naval, and logistic bases would be established at Hollandia to support subsequent Southwest Pacific advances northwest to the Geelvink Bay region of Dutch New Guinea. The Southwest Pacific forces would then move to Geelvink Bay about June. In the middle of the next month, according to General Sutherland's presentation, three Southwest Pacific divisions would be sent against the Arafura Sea islands, southwest of Dutch New Guinea. There, air bases would be established from which to cover later advances to the Vogelkop Peninsula and Halmahera, both scheduled for mid-September, when Central Pacific forces might be ready to move to the Palaus. If the Marianas were bypassed, however, the Palaus might then be invaded as early as mid-July. Land-based aircraft of the Southwest Pacific Area could support a July invasion of the Palaus from air bases in the Hollandia and Geelvink Bay regions. If air bases on the Vogelkop, Halmahera, and the Arafura Sea islands proved inadequate to provide left flank protection for the move into the Philippines, then airdrome sites on Ambon Island might also be seized in September or October. The entry into the Philippines would be effected at southeastern Mindanao on 15 November 1944. Yet for all of this, MacArthur needed something he did not have, the Pacific Fleet's aircraft carriers. After concluding the Marshall islands campaign, Admiral Nimitz argued that the next move would be to bypass Truk and invade the southern Marianas and the Palaus islands to further neutralize the Carolines. To seize the Philippines a good fleet base would be required in the western Pacific. Nimitz proposed seizing Ulithi atoll, around midway between the Marianas and Palaus. Nimitz also argued the case for Woleai in the Carolines, 400 miles south of the Marianas. By early March, the Joint Chiefs of Staff thus met at the Washington Planning Conferences with Nimitz and Lieutenant-General Richard Sutherland, to hear about their plans and discuss what the best course of action would be. In the end, on March 12th, they issued a new directive for operations in 1944. The Joint Chiefs ordered MacArthur to cancel his Kavieng operation and instead to complete the neutralization of Rabaul and Kavieng with minimum forces necessary. The Southwest Pacific's forces were to jump from eastern New Guinea to Hollandia on April 15, thus bypassing Wewak and Hansa Bay, with the mission to develop an air center from which heavy bombers could start striking the Palaus and Japanese air bases in western New Guinea and Halmahera. Once Hollandia was secured, MacArthur was to conduct operations northwest along the northern New Guinea coast in preparation for the invasion of the Palaus and Mindanao. The target date for the Southwest Pacific's landing on Mindanao in the Philippines was set for November 15. Admiral Nimitz, in turn, was ordered to cancel his Truk operation and to speed the aerial neutralization of Truk, Woleai, and other Japanese bases in the central and eastern Carolines. He was also directed to conduct heavy carrier strikes against the Marianas, the Carolines and the Palaus, and to provide carrier support and amphibious means for the Southwest Pacific's landings in the Hollandia area. The Marianas would be occupied by Central Pacific forces beginning in mid June and Palaus by mid September. The Joint Chiefs, were looking to extend Allied control over the eastern approaches to the Philippines and Formosa and to secure air and naval bases from which to support operations against Mindanao, Formosa, and the China coast. The invasion of the Admiralty and Green Islands led the Americans to seize full control over the South Pacific. This allowed the US Navy to begin sending destroyers to harass the Japanese at Rabaul and Kavieng. Admiral Halsey at Guadalcanal assembled an invasion force to hit Kavieng. When he heard about the decision to cancel the Kavieng invasion, he searched for another task for the boys he got together. He decided to capture the Emirau island, lying halfway between Kavieng and the Admiralties, thinking it could be the last link to strangle Rabaul. For what would be the last operation of Cartwheel, Admiral Wilkinson put Commodore Reifsneider in command of the amphibious operation and assigned Lieutenant-Colonel Alan Shapley's 4th Marines to carry out the landing. As a preliminary, Admiral Griffin's Task Force 36, formed around four battleships and two escort carriers, also bombarded Kavieng and its nearby airfields on March 20th. The bombardment gave Rear-Admiral Tamura Ryukichi the impression that the expected invasion by Allied forces was imminent and he gave the order to kill all the European prisoners in Kavieng. At least 25 of them were executed in the Kavieng Wharf Massacre, which later led to six of the perpetrators being sentenced for war crimes in 1947. Sentenced to death by hanging, Tamura was executed at Stanley Prison on March 16, 1948. Meanwhile Reifsneider's convoy departed Guadalcanal in two echelons, successfully reached the unoccupied Emirau Island at 6:05am. The Marines of the two assault battalions, the 1st and 2nd Battalions, 4th Marines, traveled on nine high speed transports while the remainder of the force were on the dock landing ships, Epping Forest, Gunston Hall and Lindenwald, and the attack transport Callaway. One LSD carried the 66 LVTs for crossing Emirau's fringing reef, one carried three LCTs, two of them loaded with tanks, and the third carried three LCTs with radar sets and anti-aircraft guns. The LVTs were launched, and the assault troops transferred to the amphibious tractors using the APDs' boats, supplemented by those from Callaway while F4U Corsairs of VMF-218 flew overhead to make a last-minute check of the island for any signs of the Japanese. The assault waves touched down on schedule. The reserve 3rd Battalion's boats grounded on the reef soon afterwards, and its marines waded ashore through knee deep water. The only problem encountered was with launching the LCTs carrying the tanks. The LSD's flooding mechanism failed and the LCTs had to be dragged out by a fleet tug. While the detachment sent to occupy Elomusao Island was approaching the beach, some supposed opposition caused the amphibious tractors and then a destroyer to open fire, and a man was wounded by a shell fragment. After all of this…well the Marines were told by the natives the Japanese had left Emirau two months before and only a small detachment remained on Mussau Island. Thus 3727 troops and 844 tons of cargo were ashore by nightfall, when the ships sailed; and within a month, some 18,000 men and 44,000 tons of supplies had been landed and it had become a motor torpedo base that could keep watch on the north coast of New Ireland. As for the Japanese Admiral Koga was planning to carry out a desperate program of reorganization, including the creation of the Mobile Fleet. Admiral Ozawa's 1st Mobile Fleet was formed by the 2nd and 3rd Fleets; consisting of most of the IJN's warships. This would leave the combined fleet as a mere administrative organization. Land-based forces in the Central Pacific were expanded, their main base was at Tinian; Saipan was fortified and it became the new fleet HQ. Fuel shortages and loss of tankers to submarine attacks had become so severe, Admiral Ozawa's new command would have to remain within the Singapore zone. They would operate close to the Dutch East Indies oilfield and within Japanese waters for training. Koga also prepared a new defensive plan, with the inner perimeter now extending from the Kuriles to the Nanpo Islands, then the Marianas and the Carolines to the west end of New Guinea. He also drew up plans for the formation of a 3rd Aircraft Carrier Fleet, in three divisions, each composed of three carriers. It looked very impressive on paper, but the reality was that the 3rd division actually consisted of two converted tankers the Zuiho and Chitose and the converted naval auxiliary ship Chiyoda. Furthermore, the carriers lacked any experienced pilots, with most of them having been lost around Rabaul and in the Solomons and Marshalls. Thus, new pilots for the three carrier divisions would have to be trained. Finally, he developed Plan Z, a strike against the American fleet the moment it entered the Philippine Sea. For this decisive battle, that in his eyes could allow the Japanese to win an “honorable peace”, Koga wanted to be prepared to use 500 planes on the carriers and another 500 on the islands, so he needed to increase the Japanese air force by about 50%, something that would be hard to achieve. I would like to take this time to remind you all that this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Please go subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry after that, give my personal channel a look over at The Pacific War Channel at Youtube, it would mean a lot to me. And with that the South Pacific was liberated from the Japanese Empire. Operation Cartwheel was effectively done. The allies were squeezing the Japanese empire back to the home islands and honestly it was a good time to negotiate a peace on the side of the Japanese. But they would not do so, always on the search for the famed decisive victory.

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James Graham: CEO of Recce Pharmaceuticals

BioBoss

Play Episode Listen Later Feb 24, 2024 21:06 Transcription Available

James Graham, CEO of Recce Pharmaceuticals, shares his thoughts with BioBoss host John Simboli about leadership in biopharma and how Recce is working to develop a new class of synthetic anti-infectives designed to address the threat of antibiotic-resistant superbugs.

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The Ultimate Trail Running Handbook, by Claire Maxted

Running Book Reviews with Alan and Liz

Play Episode Listen Later Nov 15, 2023 88:23

In this episode we had the pleasure of chatting with Claire Maxted (a.k.a. Wild Ginger Runner) about her book, The Ultimate Trail Running Handbook, and also found out that she is currently writing her second book which will be specifically for ultra trail runners!The Ultimate Trail Running Handbook is not called “ultimate” for no reason. It goes through many topics in a beginner friendly way with lots of lists and pictures. Almost every trail running question is touched on during the 7 chapters and there are also training plans, strength training exercises, and stretches for post-run. The chapter titles are:Quick StartSkills and TechniquesTraining and PlansBeat InjuryTrail GearNutrition and HydrationRaces and ChallengesIn case you don't already know Claire Maxted, she is co-founder and former editor of Trail Running magazine. She now runs the YouTube channel Wild Ginger Running , creating films packed with trail and ultra-running advice, athlete interviews, gear reviews and race recces (see definition below if you're like Liz and thought this word might be a typo, LOL) . Her website is www.wildgingerrunning.co.uk where you can find places to buy her book online if you don't have an independent book store nearby. You will also find links to all the places where you can find her content online.For non-UK born listeners, Collins dictionary provides the following information for the word "recce":Word forms: plural, 3rd person singular present tense recces, present participle recceing, past tense, past participle recced.VERBIf you recce an area, you visit that place in order to become familiar with it. People usually recce an area when they are going to return at a later time to do something there. [British, old-fashioned]The first duty of a director is to recce his location. [VERB noun]Recce is also a noun.Uncle Jim took the air rifle and went on a recce to the far end of the quarry. Support the showAny feedback or suggestions on this review or any of our other podcast episodes would be greatly welcomed. Leave us a review using your favorite podcast player or contact us on social media.Facebook: https://www.facebook.com/runningbookreviews/Twitter: https://twitter.com/reviews_runningInstagram: https://www.instagram.com/runningbookreviews/ Podcast webpage: https://runningbookreviews.buzzsprout.com If you have been enjoying the podcast and want more, you can find some extras on our By Me a Coffee site! https://www.buymeacoffee.com/AlanandLiz

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146: Sleeper Cells, Insurgents, Guerrilla, and Getting Recce Wrong

REDACTED Culture Cast

Play Episode Listen Later Oct 24, 2023 33:24

We're hearing politicians and pundits wax poetic about the threat of sleeper cell terrorists attacking America. All attention is then directed at the idea of an illegal alien entering the United States through a porous southern border, to then integrate into a community keeping nefarious plots and abilities under the floorboards until they receive a call from a foreign commander. What's more close to home, is that the idea of what we call a sleeper cell already exists in America, only they're chanting Black Lives Matter and burning down a police precinct. Further, Gun Culture has put a great interest in the idea of Recce or reconnaissance, and the interest is genuine, only the terms are a little off. Books mentioned in this episode: "Why Young Men" by Jamil Jivanihttps://www.amazon.com/gp/search?ie=UTF8&tag=redacted00-20&linkCode=ur2&linkId=6d4868dc7e1a33a34ee0ef85b6c35173&camp=1789&creative=9325&index=books&keywords=why young men"War of the Flea" by Robert Taberhttps://www.amazon.com/gp/search?ie=UTF8&tag=redacted00-20&linkCode=ur2&linkId=31c987b8d66d0e065c6b69fdd973391d&camp=1789&creative=9325&index=books&keywords=war of the fleaSupport the REDACTED Culture Cast at redactedculture.locals.comSSP and boutique products at redactedllc.comFollow us on Instagram at @redactedllc

Podcast Extra | Season 5 Preview (S4 E12)

Empowered Patient Podcast

Play Episode Listen Later Aug 16, 2023 0:51

Season 4 is coming to a close and the podcast will be taking a break until the fall. Listen in to find out what is coming up for season 5.Feel free to contact Captain Adam Orton with any comments or questions:armyconnect-connectionarmee@forces.gc.caMeet our host Captain Adam Orton: Bio | VideoConnect with the Canadian Army on social media:Facebook | Twitter | Instagram | YouTubeVisit Forces.ca if you are considering a career in the Army.Copyright Information© His Majesty the King in Right of Canada, as represented by the Minister of National Defence, 2023

Developing Synthetic Anti-Infectives New Class of Antibiotics to Overcome Antimicrobial Resistance with James Graham Recce Pharmaceuticals TRANSCRIPT

Play Episode Listen Later Jul 31, 2023

James Graham is the CEO of Recce Pharmaceuticals, a biotechnology company focused on the global antibiotic-resistant patient population. This new class of synthetic antibiotics takes a broad-spectrum approach to kill bacterial infections, which continue to mutate, rendering existing antibiotics ineffective. The founding inventor of Recce is Dr. Graham Melrose, the grandfather of James, who has grown this idea into one of the top-performing biotech stocks in Australia. James explains, "As you may know, by my accent, I'm an Australian. I think Australia found the first penicillin, which worked well for everyone around the world for a number of years. But it's time for a new penicillin, penicillin 2.0, or one entirely synthetic, not reliant on existing natural processes. And that's what we've fundamentally started with, beginning with the end in mind that is Recce antibiotics. So I really say the challenge, the silent pandemic is right upon us. You only have to look at the AMR resistance rates. I think raising at about 10% each year, certainly in certain antibiotic or indication groups. If we don't do something, we're just going to have these useless drugs that no one will pay the price for anyway. The business model will be broken, and everybody will be out of options. It's really the pandemic before us." "I hinted that R327 is synthetic. It's entirely synthetic when all existing antibiotics to date are naturally derived. So the way antibiotics and bacteria have always worked is that you find something in nature by way of the antibiotic. The bacteria are too smart. They evolve too quickly, and let's begin with the end in mind and create something that will work against all types of bacteria, gram-positive gram-negative in their hypercellular mutated forms, and keep on working with repeated use." "And in the case of my origins with Recce, the inventor, Dr. Graham Melrose, is actually my grandfather. He turned 90 years old about a little over a month ago, and he's the guy who was the head of Johnson & Johnson Australasia for about a decade. He is the foundational inventor of this compound. And he and I started this company. He's the inventor. I just gave him a bit of money, and off we went. That's the easy part. He started identifying the ideal compound in his garage in Perth in Western Australia. If anyone knows where that is, it's actually the most isolated city in the world." @ReccePharma #AntimicrobialResistance #AMR #SuperBugs #Sepsis #UTIs #Urosepsis #SyntheticAntiInfective #Antibiotics #AustraliaBioTech recce.com.au Listen to the podcast here

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Developing Synthetic Anti-Infectives New Class of Antibiotics to Overcome Antimicrobial Resistance with James Graham Recce Pharmaceuticals

Empowered Patient Podcast

Play Episode Listen Later Jul 31, 2023 21:20

James Graham is the CEO of Recce Pharmaceuticals, a biotechnology company focused on the global antibiotic-resistant patient population. This new class of synthetic antibiotics takes a broad-spectrum approach to kill bacterial infections, which continue to mutate, rendering existing antibiotics ineffective. The founding inventor of Recce is Dr. Graham Melrose, the grandfather of James, who has grown this idea into one of the top-performing biotech stocks in Australia. James explains, "As you may know, by my accent, I'm an Australian. I think Australia found the first penicillin, which worked well for everyone around the world for a number of years. But it's time for a new penicillin, penicillin 2.0, or one entirely synthetic, not reliant on existing natural processes. And that's what we've fundamentally started with, beginning with the end in mind that is Recce antibiotics. So I really say the challenge, the silent pandemic is right upon us. You only have to look at the AMR resistance rates. I think raising at about 10% each year, certainly in certain antibiotic or indication groups. If we don't do something, we're just going to have these useless drugs that no one will pay the price for anyway. The business model will be broken, and everybody will be out of options. It's really the pandemic before us." "I hinted that R327 is synthetic. It's entirely synthetic when all existing antibiotics to date are naturally derived. So the way antibiotics and bacteria have always worked is that you find something in nature by way of the antibiotic. The bacteria are too smart. They evolve too quickly, and let's begin with the end in mind and create something that will work against all types of bacteria, gram-positive gram-negative in their hypercellular mutated forms, and keep on working with repeated use." "And in the case of my origins with Recce, the inventor, Dr. Graham Melrose, is actually my grandfather. He turned 90 years old about a little over a month ago, and he's the guy who was the head of Johnson & Johnson Australasia for about a decade. He is the foundational inventor of this compound. And he and I started this company. He's the inventor. I just gave him a bit of money, and off we went. That's the easy part. He started identifying the ideal compound in his garage in Perth in Western Australia. If anyone knows where that is, it's actually the most isolated city in the world." @ReccePharma #AntimicrobialResistance #AMR #SuperBugs #Sepsis #UTIs #Urosepsis #SyntheticAntiInfective #Antibiotics #AustraliaBioTech recce.com.au Download the transcript here

ceo australia australian developing overcome perth western australia synthetic antibiotics pharmaceuticals amr new class james graham antimicrobial resistance recce

Army Sergeant Major (S4 E11)

Play Episode Listen Later Jul 26, 2023 22:06

The Army Sergeant Major plays a significant role in the lives of all non-commissioned soldiers. But how? Chief Warrant Officer James Smith talks about his role as senior advisor to the Army Commander, lends his perspective on what it takes to be a good leader, plus gives a preview of what's to come with regards to kit and equipment. He also has advice on how to deal with some of the challenges of being a soldier.CWO James Smith's Bio Feel free to contact Captain Adam Orton with any comments or questions:armyconnect-connectionarmee@forces.gc.caMeet our host Captain Adam Orton: Bio | VideoConnect with the Canadian Army on social media:Facebook | Twitter | Instagram | YouTubeVisit Forces.ca if you are considering a career in the Army.Copyright Information© His Majesty the King in Right of Canada, as represented by the Minister of National Defence, 2023

Billy Recce, "Come Out" - The TV Dudes Interview

The TV Dudes Podcast

Play Episode Listen Later Jun 6, 2023 27:02

This week, Les chats with musical theater writer Billy Recce! The award-winning young singer and songwriter has a new pop single “Come Out” which features a fabulous music video. Billy's new song continues the quirky pop sounds of his debut album The Perks of Being a Snowflake (links below) Billy is also known for his Broadway-bound musical about Heidi Fleiss, Little Black Book, his Chick-Fil-A queer musical satire Fowl Play, and his hit Off-Broadway show, A Musical About Star Wars. A 2022 Jonathan Larson Grant finalist, Billy has been creating short form musical content on TikTok, amassing over two million views in his first month. Check it out! https://music.apple.com/us/artist/billy-recce/1437871549 https://open.spotify.com/artist/3AiFippEtEFJktQXgVMOni https://www.tiktok.com/@billyrecce

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Episode 101 – The Valentines Day assault on 59 Brigade and a Cuban tank ambush

Gunfighter Life. Be Strong & Courageous

Play Episode Listen Later Apr 16, 2023 22:37

It's the second week of January 1988 and FAPLAs 21st, 59th and 25th Brigades had taken up the front line in what was to be a three layered defenses ahead of the Tumpo Triangle, where two roads joined just north of the Tumpo River. That was aeast of Cuito Cuanavale. Behind these three Brigades, 16th and 66th hunkered down in expectation of an SADF follow up attack which had started ended on the 14th January. The third Angolan line of defence was just west of the Cuito River, manned by the 13th Brigade joined by a Cuban battalion. By now FAPLA was communicating by fixed telephone line, going back to an earlier technology which made it much more difficult for the South Africans to intercept their messages. From the beginning of January 1988 to the end of March, the SADF was going to make six frontal attacks on these well-entrenched FAPLA positions and now the Generals in Pretoria were almost literally breathing down the necks of the tactical commanders. 61 Mech, 4SAI and UNITA had been repulsed after taking ground, the South African troops disgusted as they watched the land they'd fought to seize being retaken by Angolan units around the Chambinga High Ground. The haphazard nature of the SADF's attack - part of Operation Hooper - was caused by the territory and by a confused series of orders. I recently attended talks at Voortrekkehoogte by high ranking generals of this period, they defended their decisions and made some pointed comments about false information, but I'm afraid to say that the facts speak for themselves. Let's go over a few of these and consider for yourself what was going on in these final days of South Africa's Border War. After the attack on 21 Brigade some of the Recce observation teams were moved to positions between the Cuito and Cuanavale Rivers, well behind enemy lines, north of Cuito Cuanavale. From here, the observers could see the airfield and the Cuito Bridge. The main danger for these specialists were the crocodiles, the Cuanavale River teemed with them, but after some scouring of the banks, one team led by Justin Vermaak spotted two Makoros, or canoes made from a hollowed tree trunk, and crossed over after dark. They were prepping for the next major assault which SADF HQ had indicated was supposed to take place by end January, but ended up starting almost a month after their first assault on 21st Brigade. One of the strategic weaknesses plaguing the SADF now was the slow response and planning, logistics was a big problem here hundreds of kilometers away from their bases at Rundu and Oshikati. Eventually Vermaak and his OP team found an excellent spot behind some of FAPLAs brigades, and watched 21 Brigade reorganised, digging their trenches in the same area that 4SAI had freed only a few days before. The Recces were also in a good spot to warn their 20 Brigade HQ back in Rundu when they spotted MiGs, being behind enemy lines. That would buy the South Africans a couple of minutes. They were also being warned 200km further west, teams of Recces under Johnny de Gouveia and Buks van den Burg were watching Menongue airport spotting the MiGs and choppers taking off heading towards Cuito Cuanavale. Pretoria was dithering. They eventually decided on January 25th that the rearming and new plans were ready and the nest target was not 21 Brigade, it was 59th. 61 Mech lieutenant Clive Holt explained how they all knew that 59 Brigade was the key to the FAPLA defences. FAPLAs 3 Tank Battalion was waiting in support, so this was not going to be easy. Because 59th Brigade was FAPLAs strongest, the aim was to hit them until they collapsed, then 21 and 25 Brigades would fall back towards the town - hopefully without much fight left.

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Fighting Rifle and Carbine Set Up - Setting Up A.R.-15s S.C.A.R. Recce Rifles for Defense Law Enforcement Milita and Survival

Play Episode Listen Later Mar 20, 2023 36:49

GOD Provides JESUS SavesGoodShepherdTraining.comPatreonI'm Humbled by Your Support, Thanks and Have a Blessed DayServant Milito

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Episode 161 - Recce Concepts

The Prepared Mindset Podcast

Play Episode Listen Later Mar 10, 2023 112:33

To many of us in the training community, we've become so inundated and overwhelmed with the use of the term "recce" that I don't know if we even still know what it means. It's something I have a idea about, and see a lot of information thrown around about, but haven't deeply addressed personally. I'm joined this week, by my friend Adrian, owner of Sidewinder Concepts, to do just that. We take a deep dive into the mindset and skillsets that build recce concepts. Plenty of misunderstandings are corrected, and information gaps are filled throughout our discussion. If you're some who's looking to take your training to new places, or simply have no clue if you really understand reconnaissance, you'll likely learn a few things here!

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211. Talking Optics, Recce Rifles, and More with Primary Arms

Radio Contra

Play Episode Listen Later Jan 13, 2023 52:37

Episode 211. I'm joined by Dat Trinh and Stephen Morgan of Primary Arms to talk optics, practical rifle setups, trends in the industry, and what makes them a leader in the field. The Guerilla's Guide to the Baofeng Radio is a #1 Bestseller! Nehemiah Strong discount code: SCOUT1 Radio Contra Sponsors: Civil Defense Manual Tactical Wisdom Blacksmith Publishing Radio Contra Patron Program Brushbeater Training Calendar Brushbeater Forum Palmetto State Armory Primary Arms

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Building a Recce Rifle & Bonding with It. My Origina Pracical Ar15s for Defense & Survival

Gunfighter Life. Be Strong & Courageous

Play Episode Listen Later Jan 13, 2023 33:38

GOD Provides JESUS Saves GoodShepherdTraining.com Go to Link Below to enter Raffle https://www.patreon.com/GoodSh...https://venmo.com/code?user_id... I'm Humbled by Your Support, Thanks and Have a Blessed Day.

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Episode 86 – The SAAF harried in Angola and Soviets import arms from Afghanistan

Play Episode Listen Later Jan 2, 2023 20:30

We are traveling with 5 Recce and they are planning to attack the SWAPO base that was discovered by some systematic sleuthing by Koos Stadler and Jose da Costa as you heard last episode. The base was north of Tethamutete, east of the Cubango River - and from Menongue, heavily armed, a few hundred SWAPO cadres, perhaps as many as 350 were training at what was the Eastern Front HQ. The troops gathered around for the intelligence briefing by Dave Drew before James Hills explained how the attack would unfold. A mortar platoon and two stopper groups, 51 and 53 Commando were ordered to take up their positions north of the base, led by Koos Stadler. They were to approach the base using the same route that the main force would use early the next day. A few kilometres from the target, they left the mortar platoon which setup near the track that ran east to west through the base. Commando 53 then moved directly north of the base, ready to confront any SWAPO attempting to escape north as the stopper group. Stadler headed off west of the target with 51 Commando, also following the track. These two groups formed a significant threat to any SWAPO fleeing in their direction. Just before first light, a company from 101 Battalion, soldiers from 2 Recce reserves, along with the regimental HQ and 51 Commando would assault the base led by Jose da Costa. As this attacking force arrived at the river the mortars would open fire. They took off at dusk, the trucks dropping the troops around 20 km from the target, they covered the remaining ten kilometres on foot and eventually stopped at the east west track. By 0200 they were at the forming up point, the mortar platoon was ready. Starting in January of 1987, the SA Intelligence became aware of a major Soviet airlift of heavy weapons and military supplies from Tashkent north of the Black Sea and from Moscow, all the way to Luanda the Angolan Capital. The Soviets were withdrawing this equipment from Afghanistan where they'd been roundly defeated by the Taliban with American backing. The new equipment arriving in Angola was the latest Russian material, BTR-60 APCs, BRDMS-2 ARVs, BMP-1 IFVs, all were heading south. Heavy transport aircraft were now flying into Menongue daily, carrying food, ammunition, troops. More than 400 trucks were counted traveling back and forth between central Angola and Menongue.

Episode 86 – The SAAF harried in Angola and Soviets import arms from Afghanistan

Play Episode Listen Later Jan 2, 2023 20:30

We are traveling with 5 Recce and they are planning to attack the SWAPO base that was discovered by some systematic sleuthing by Koos Stadler and Jose da Costa as you heard last episode. The base was north of Tethamutete, east of the Cubango River - and from Menongue, heavily armed, a few hundred SWAPO cadres, perhaps as many as 350 were training at what was the Eastern Front HQ. The troops gathered around for the intelligence briefing by Dave Drew before James Hills explained how the attack would unfold. A mortar platoon and two stopper groups, 51 and 53 Commando were ordered to take up their positions north of the base, led by Koos Stadler. They were to approach the base using the same route that the main force would use early the next day. A few kilometres from the target, they left the mortar platoon which setup near the track that ran east to west through the base. Commando 53 then moved directly north of the base, ready to confront any SWAPO attempting to escape north as the stopper group. Stadler headed off west of the target with 51 Commando, also following the track. These two groups formed a significant threat to any SWAPO fleeing in their direction. Just before first light, a company from 101 Battalion, soldiers from 2 Recce reserves, along with the regimental HQ and 51 Commando would assault the base led by Jose da Costa. As this attacking force arrived at the river the mortars would open fire. They took off at dusk, the trucks dropping the troops around 20 km from the target, they covered the remaining ten kilometres on foot and eventually stopped at the east west track. By 0200 they were at the forming up point, the mortar platoon was ready. Starting in January of 1987, the SA Intelligence became aware of a major Soviet airlift of heavy weapons and military supplies from Tashkent north of the Black Sea and from Moscow, all the way to Luanda the Angolan Capital. The Soviets were withdrawing this equipment from Afghanistan where they'd been roundly defeated by the Taliban with American backing. The new equipment arriving in Angola was the latest Russian material, BTR-60 APCs, BRDMS-2 ARVs, BMP-1 IFVs, all were heading south. Heavy transport aircraft were now flying into Menongue daily, carrying food, ammunition, troops. More than 400 trucks were counted traveling back and forth between central Angola and Menongue.

Episode 85 – Small teams missions behind enemy lines and the courage of 7 Med

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Play Episode Listen Later Dec 25, 2022 23:18

We've heard about the 1 Recce and 4 Recce and the covert war throughout this series, and at times, I've included the voices or the individual stories where possible. Unfortunately there is just not enough space and time to include everyone's personal views or their memories. However, in this episode, I'm going to concentrate on two specific Special Forces members because they epitomize two different aspects of the South Africans who were involved in this 23 year war. The first instance is one that is chilling and horrific, where MPLA soldiers let their base instincts take over and when they realized they weren't getting what they wanted, lead to the execution of 7 Medical Battalion corporal, Bruce Fidler (Feed-luh) in September 1985. The other illuminates the visceral and tractical elements of operating in an African bush scenario behind enemy lines with join Koos Stadler a year later in late 1986 as he collected reconnaissance information as an operator. First, Bruce Fidler. His story exemplifies courage and has a more recent resonance because the unit he fought in, the 7th Medical Battalion, was involved in the infamous attack on South African paratroopers in the Central African Republic town of Bangui, in 2013. For those who don't know this story, just a quick reminder. The SANDF was involved in peacekeeping operations in central Africa – and 200 paratroopers were surrounded in Bangui by at least 3 000 rebels. In a two-day battle, thirteen SANDF parabats died, but remarkably they are thought to have killed up to 800 rebels – all this without artillery, armour or air support. Afterwards, Corporal Mandla Maxwell Ngobese of the 7 Med was awarded the SANDF's Leopard Decorations – and like his predecessor Bruce Fidler, his was a case of extreme courage under fire. Changing gear and moving forward to where we left off last episode, on 25th October 1986 the whole of 5 Recce had been congregated in Oshivelo training area just north east of Etosha Pan. Having spent time in the bush there myself, it is like any other part of Ovamboland, hot, flat, full of thorn bushes and snakes where the dust hangs in the air at dusk and coats your equipment – jamming automatic rifles and sticking in your throat. This is just across the red line area, which divides the farmlands to the south – including the triangle of death - from the operational area in the north closer to the cutline. The Recces were training for something called Operation Colosseum which was a planned attack deep into Angola on SWAPO HQ in the Eastenr Front. I'm using Koos Stadler's excellent book called Recce, Small Team Missions behind enemy lines as reference along with other source material for this episode.

Episode 85 – Small teams missions behind enemy lines and the courage of 7 Med

africa courage african missions south africans med angola special forces behind enemy lines central african republic bangui mpla recce sandf

Play Episode Listen Later Dec 25, 2022 23:18

We've heard about the 1 Recce and 4 Recce and the covert war throughout this series, and at times, I've included the voices or the individual stories where possible. Unfortunately there is just not enough space and time to include everyone's personal views or their memories. However, in this episode, I'm going to concentrate on two specific Special Forces members because they epitomize two different aspects of the South Africans who were involved in this 23 year war. The first instance is one that is chilling and horrific, where MPLA soldiers let their base instincts take over and when they realized they weren't getting what they wanted, lead to the execution of 7 Medical Battalion corporal, Bruce Fidler (Feed-luh) in September 1985. The other illuminates the visceral and tractical elements of operating in an African bush scenario behind enemy lines with join Koos Stadler a year later in late 1986 as he collected reconnaissance information as an operator. First, Bruce Fidler. His story exemplifies courage and has a more recent resonance because the unit he fought in, the 7th Medical Battalion, was involved in the infamous attack on South African paratroopers in the Central African Republic town of Bangui, in 2013. For those who don't know this story, just a quick reminder. The SANDF was involved in peacekeeping operations in central Africa – and 200 paratroopers were surrounded in Bangui by at least 3 000 rebels. In a two-day battle, thirteen SANDF parabats died, but remarkably they are thought to have killed up to 800 rebels – all this without artillery, armour or air support. Afterwards, Corporal Mandla Maxwell Ngobese of the 7 Med was awarded the SANDF's Leopard Decorations – and like his predecessor Bruce Fidler, his was a case of extreme courage under fire. Changing gear and moving forward to where we left off last episode, on 25th October 1986 the whole of 5 Recce had been congregated in Oshivelo training area just north east of Etosha Pan. Having spent time in the bush there myself, it is like any other part of Ovamboland, hot, flat, full of thorn bushes and snakes where the dust hangs in the air at dusk and coats your equipment – jamming automatic rifles and sticking in your throat. This is just across the red line area, which divides the farmlands to the south – including the triangle of death - from the operational area in the north closer to the cutline. The Recces were training for something called Operation Colosseum which was a planned attack deep into Angola on SWAPO HQ in the Eastenr Front. I'm using Koos Stadler's excellent book called Recce, Small Team Missions behind enemy lines as reference along with other source material for this episode.

S&YE101 - Gravel Express

Subie & YOU!

Play Episode Listen Later Dec 12, 2022 86:35

Maya is our guest today on the podcast to talk about her two Subarus, her experience volunteering at Rally events, her artwork and her new pup Recce. Be sure to give this episode with @gravel_express a listen!Links from the show, links to sponsors and discount partners, and ways to support the podcast:Gravel Express Instagram: https://www.instagram.com/gravel_express/ Foliomotive Website:https://foliomotive.com/ - - - - - - - - - - - - - - - - - - - - - - - - - - -Subie & YOU! Podcast Merch is HERE!!!:https://subieandyoupodcast.com/ Rep your favorite podcast with some Subie & YOU! Podcast gear!! Also on the website you will find all the episodes, reviews from Apple Podcast, the About page, and a place to purchase car decals to show your love for the podcast by adding a decal, which we know adds 5 HP to your Subaru!!- - - - - - - - - - - - - - - - - - - - - - - - - - -Sponsors of the Podcast:REIKA VSUse code SubieYou10 for 10% off purchases!Subie & YOU! on Reika VS Website:reikavs.com/subieandyou/ Mele Design FirmWebsite:https://meledesignfirm.com/ Spider No Drill Roof RackUse code subieandyou to get 10% off a rack for your Subie!!https://www.spiderroofrack.com/ - - - - - - - - - - - - - - - - - - - - - - - - - - - Other Brands Offering DiscountsOrbis Overlanding10% discount off Orbis Overlanding and partnering car products(excludes apparel)Discount code: subieandyou Website:www.orbisoverlanding.com/ That Subie ChickUse code SUBIEANDYOUPODCAST for 10% off your purchase!Website:https://www.subiechick.com/ YescomUSA10% off awning with LED light bar.Discount code: SUBIE&YOU10Website:www.yescomusa.com/

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Episode 79 – A shootout on a Cabinda beach and the capture of Cpt Wynand du Toit

Play Episode Listen Later Nov 13, 2022 23:24

Last episode we covered one of 32 Battalion's darkest days, the mauling they received at the hands of SWAPO on 11th February 1985, where Charlie Company walked straight into one of the better prepared SWAPO bases after taking what some say was a short cut. The death toll on the South African side was heavy, 13 soldiers from 32 Battalion's Charlie company died either during the firefight or of their wounds later, 15 SWAPO were also killed. 32 survivors described what happened that day as a massacre as Charlie Company stumbled upon 100 SWAPO soldiers in trenches who were armed with 82mm mortars and machine guns and proceeded to mow down the soldiers of probably the best known SADF battalion. Thus, Operation Forte came to a bitter end, the Battalion had been operating deep inside Angola in support of UNITA but by the end of May 1985, 32 withdrew from Angola. The Joint Monitoring Commission came to an end at the same time. Normal service resumed as they say. With the JMC done and dusted, the covert war increased in intensity to a full-scaled mechanized war on both sides. In a few months, FAPLA and the Cubans were to launch an attack on UNITA in the south east of the country. But first, 4 Recce found itself embroiled in their next Operation. This was an ambitious project and took the special forces way beyond their normal stomping ground. They were heading to Cabinda Province far to the north, the province that produces most of Angola's oil and gas. It's an enclave inside the DRC, alongside the Congo River. Operation Argon in May 1985 would leave two Recces dead, one captured, and the South African government in a diplomatic pickle. Four Recce were once again the go-to organization seeing that they had already been successful in blowing up a pipeline in Cabinda in June 1984. Captain Wynand du Toit was to be Mission Commander, and Captain Krubert Nel was his 2 IC. I'm going to mention the others involved because this is one of the most viscious face to face fights involving the Recces of the entire war. Staff Sergeant Amilear Queiroz and Maddies Adam were joined by Corporals Michael Hough, Gert Engelbrecht, Toby Tablai, Rowland Liebenberg and Louis van Breda. The medical support were going to be very busy indeed -and it was fortunate for those who were going to return injured that two doctors were on board the sub, with Doctor Deon Erasmus and Frans Verster who were both qualified operators as well as surgeons part of this mission

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Episode 79 – A shootout on a Cabinda beach and the capture of Cpt Wynand du Toit

Play Episode Listen Later Nov 13, 2022 23:24

Last episode we covered one of 32 Battalion's darkest days, the mauling they received at the hands of SWAPO on 11th February 1985, where Charlie Company walked straight into one of the better prepared SWAPO bases after taking what some say was a short cut. The death toll on the South African side was heavy, 13 soldiers from 32 Battalion's Charlie company died either during the firefight or of their wounds later, 15 SWAPO were also killed. 32 survivors described what happened that day as a massacre as Charlie Company stumbled upon 100 SWAPO soldiers in trenches who were armed with 82mm mortars and machine guns and proceeded to mow down the soldiers of probably the best known SADF battalion. Thus, Operation Forte came to a bitter end, the Battalion had been operating deep inside Angola in support of UNITA but by the end of May 1985, 32 withdrew from Angola. The Joint Monitoring Commission came to an end at the same time. Normal service resumed as they say. With the JMC done and dusted, the covert war increased in intensity to a full-scaled mechanized war on both sides. In a few months, FAPLA and the Cubans were to launch an attack on UNITA in the south east of the country. But first, 4 Recce found itself embroiled in their next Operation. This was an ambitious project and took the special forces way beyond their normal stomping ground. They were heading to Cabinda Province far to the north, the province that produces most of Angola's oil and gas. It's an enclave inside the DRC, alongside the Congo River. Operation Argon in May 1985 would leave two Recces dead, one captured, and the South African government in a diplomatic pickle. Four Recce were once again the go-to organization seeing that they had already been successful in blowing up a pipeline in Cabinda in June 1984. Captain Wynand du Toit was to be Mission Commander, and Captain Krubert Nel was his 2 IC. I'm going to mention the others involved because this is one of the most viscious face to face fights involving the Recces of the entire war. Staff Sergeant Amilear Queiroz and Maddies Adam were joined by Corporals Michael Hough, Gert Engelbrecht, Toby Tablai, Rowland Liebenberg and Louis van Breda. The medical support were going to be very busy indeed -and it was fortunate for those who were going to return injured that two doctors were on board the sub, with Doctor Deon Erasmus and Frans Verster who were both qualified operators as well as surgeons part of this mission

normal beach operation south africans capture angola shootouts ic battalion drc cubans toit breda unita jmc cabinda congo river recce wynand charlie company swapo sadf

Episode 76 – Turned SWAPO cadres, Recce pseudo-operations & Soviet air strategy

Play Episode Listen Later Oct 23, 2022 18:57

It's 1984 and the special forces have been busy as you heard in the last episode. The waterborne operations were on the go, but so too were ops into southern Angola with 32 Battalion changing its colours so to speak. They began to patrol the area dressed in SWAPO uniforms, so much for the SADF's promise to adhere to the terms of a Joint Monitoring Commission where they'd promised to pull all their forces out of the region. It became a game of cat and mouse between the SADF and FAPLA about who'd be tripped up in the lying game first. The special Forces were increasing what were known as pseudo operations – which the Selous Scots had used to great effect during the Rhodesian Bush War, or the Zimbabwean War for independence depending on your political position. A large number of the Scouts had made their way south to join the SADF and were now integrated in different units. By August 1984 SWAPO had declared the far east of Ovamboland as a liberated area, with the cadres roaming around the bush and villages freely, visiting kraals and receiving food and support from the locals. They also collected intelligence from the villagers, and the SADF's hearts and minds campaign which elements of 32 had tried so hard to initiate had failed. The Recces had a new role to play here. The vegetation in this part of the border is extremely dense, with large thickets of acacia thorn trees, and the going was hard. The sand is soft in most places along the rivers, but this also made it far easier to track SWAPO when they crossed the cutline. But what's good for the goose is good for the gander – SWAPO could also track the special forces. Further west, the SADF had setup a special forces area in Ondangwa called Fort Rev, where the pseudo-operations concept was being fully exploited. It was a secret base alongside Ondangwa Air Force Base, and was full of ex-SWAPO soldiers. These men were known as masters of the bush, despite what the SADF soldier thought about them. The Recces had a completely different view of their enemy and were now working with dozens of SWAPO who'd switched sides. These men knew the area intimately and could speak the local dialects. They were smuggled in an out of this secret base for obvious reasons. By September 1984 and the Soviets had just taken over command in Angola from the Cubans, shocked into action by FAPLAs defeat during Operation Askari. The Soviets wanted to start a series of large-scaled offensives with all the firepower at their disposal to crush UNITA in the east. The Cubans preferred the Chinese way, the Vietkong way, to adopt a classic counterinsurgency approach. The Russians began to taunt the Cubans for failing to stand up and fight, always darting about, and avoiding full-scale clashes with the South Africans. Moscow was going to deploy their new air support systems in two phases. Firstly they would support the MPLA more closely, perhaps even using ground support, and second, they would increase air support in Zambia, Zimbabwe and Mocambique.

Episode 76 – Turned SWAPO cadres, Recce pseudo-operations & Soviet air strategy

Play Episode Listen Later Oct 23, 2022 18:57

It's 1984 and the special forces have been busy as you heard in the last episode. The waterborne operations were on the go, but so too were ops into southern Angola with 32 Battalion changing its colours so to speak. They began to patrol the area dressed in SWAPO uniforms, so much for the SADF's promise to adhere to the terms of a Joint Monitoring Commission where they'd promised to pull all their forces out of the region. It became a game of cat and mouse between the SADF and FAPLA about who'd be tripped up in the lying game first. The special Forces were increasing what were known as pseudo operations – which the Selous Scots had used to great effect during the Rhodesian Bush War, or the Zimbabwean War for independence depending on your political position. A large number of the Scouts had made their way south to join the SADF and were now integrated in different units. By August 1984 SWAPO had declared the far east of Ovamboland as a liberated area, with the cadres roaming around the bush and villages freely, visiting kraals and receiving food and support from the locals. They also collected intelligence from the villagers, and the SADF's hearts and minds campaign which elements of 32 had tried so hard to initiate had failed. The Recces had a new role to play here. The vegetation in this part of the border is extremely dense, with large thickets of acacia thorn trees, and the going was hard. The sand is soft in most places along the rivers, but this also made it far easier to track SWAPO when they crossed the cutline. But what's good for the goose is good for the gander – SWAPO could also track the special forces. Further west, the SADF had setup a special forces area in Ondangwa called Fort Rev, where the pseudo-operations concept was being fully exploited. It was a secret base alongside Ondangwa Air Force Base, and was full of ex-SWAPO soldiers. These men were known as masters of the bush, despite what the SADF soldier thought about them. The Recces had a completely different view of their enemy and were now working with dozens of SWAPO who'd switched sides. These men knew the area intimately and could speak the local dialects. They were smuggled in an out of this secret base for obvious reasons. By September 1984 and the Soviets had just taken over command in Angola from the Cubans, shocked into action by FAPLAs defeat during Operation Askari. The Soviets wanted to start a series of large-scaled offensives with all the firepower at their disposal to crush UNITA in the east. The Cubans preferred the Chinese way, the Vietkong way, to adopt a classic counterinsurgency approach. The Russians began to taunt the Cubans for failing to stand up and fight, always darting about, and avoiding full-scale clashes with the South Africans. Moscow was going to deploy their new air support systems in two phases. Firstly they would support the MPLA more closely, perhaps even using ground support, and second, they would increase air support in Zambia, Zimbabwe and Mocambique.

Episode 75 – Russian OSA2 missile boats targeted in 1984's Operation Nobilis

Play Episode Listen Later Oct 16, 2022 20:27

This is episode 75 and we're covering events in 1984 where various issues had arisen. The South Africans and the Angolans had been jointly patrolling southern Angola in what was supposed to be the preamble to peace in Namibia. But the Joint Monitoring process had failed by July 1984 with SWAPO continuing to occupy the southern region of Angola, and the South Africans continuing to supply UNITA. This JMC process was always doomed some say, but at the start there were signs that FAPLA and the SADF could work together. Unfortunately for the many hundreds who were still to die, that good faith faded away rapidly and there was no chance of a proper cease fire. While the JMC continued operating in name, on the ground things were going from bad to worse. Eventually the whole exercise would be terminated in mid-1985, but before we get there it's important to focus on special operations of 1984. You heard how the SADF special forces, specifically the Recces, had been tasked with disrupting Angolan maritime resources and last episode we covered what happened during Operation Bouganvilia earlier in 1984. The next op was called Nobilis where seaborne operators were going to try and and blow up the ASO 2 Missile boats the Angolan navy had secured from the Russians. Earlier in the war, the SA Navy was somewhat scathing of the Angolan capacity, but everything changed when the OSA 2 missile boats arrived in 1982. They added a new and more deadly dimension to Luanda's capacity. By late 1983 there were six of these vessels deployed to ports like Soyo, Lobito and Mocamedes and Luanda. Eventually, 4 Recce was given the project to sink three OSA missile boats inside Luanda harbour during the dark moon period at the end of July 1984. It was important to allow UNITA to claim the attack, so the mines were going to be attached to these ships at only 1 to 1.5 meters below the surface. The South Africans used sophisticated underwater breathing systems allowing them to approach much deeper, so they hoped the shallow attachment of the mines would convince the Russians and the Angolans that it was the rebel movement and not the SA special Forces.

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Episode 75 – Russian OSA2 missile boats targeted in 1984's Operation Nobilis

Griffin Armament's Dwell Time podcast

Play Episode Listen Later Oct 16, 2022 20:27

This is episode 75 and we're covering events in 1984 where various issues had arisen. The South Africans and the Angolans had been jointly patrolling southern Angola in what was supposed to be the preamble to peace in Namibia. But the Joint Monitoring process had failed by July 1984 with SWAPO continuing to occupy the southern region of Angola, and the South Africans continuing to supply UNITA. This JMC process was always doomed some say, but at the start there were signs that FAPLA and the SADF could work together. Unfortunately for the many hundreds who were still to die, that good faith faded away rapidly and there was no chance of a proper cease fire. While the JMC continued operating in name, on the ground things were going from bad to worse. Eventually the whole exercise would be terminated in mid-1985, but before we get there it's important to focus on special operations of 1984. You heard how the SADF special forces, specifically the Recces, had been tasked with disrupting Angolan maritime resources and last episode we covered what happened during Operation Bouganvilia earlier in 1984. The next op was called Nobilis where seaborne operators were going to try and and blow up the ASO 2 Missile boats the Angolan navy had secured from the Russians. Earlier in the war, the SA Navy was somewhat scathing of the Angolan capacity, but everything changed when the OSA 2 missile boats arrived in 1982. They added a new and more deadly dimension to Luanda's capacity. By late 1983 there were six of these vessels deployed to ports like Soyo, Lobito and Mocamedes and Luanda. Eventually, 4 Recce was given the project to sink three OSA missile boats inside Luanda harbour during the dark moon period at the end of July 1984. It was important to allow UNITA to claim the attack, so the mines were going to be attached to these ships at only 1 to 1.5 meters below the surface. The South Africans used sophisticated underwater breathing systems allowing them to approach much deeper, so they hoped the shallow attachment of the mines would convince the Russians and the Angolans that it was the rebel movement and not the SA special Forces.

russian boats operation south africans forces targeted angola namibia missile osa aso luanda angolan unita jmc lobito nobilis recce swapo angolans sadf

Customer Call In Session Part 1

Play Episode Listen Later Oct 14, 2022 27:09

In this episode, Jack and Cole get the chance to talk with Mike, an active Griffin Armament user. Griffin wanted to reach out to their consumers and give an opportunity to spread real opinions to other potential buyers from a customer's point of view. Mike gives a brief breakdown of why he started competitively shooting and how he ultimately chose the Recce 5™ over other silencers due to his own thorough research. If you'd like an opportunity to be on the next call in session, feel free to reach out to our customer service team by visiting: https://www.griffinarmament.com/contact-us/customer-service/ Follow us on Instagram: @griffin_armament Follow us on Facebook: @griffinarmament

recce

Episode 74 – FAPLA/SADF joint patrols hit a wobble & Recce Op Bouganvilia

Play Episode Listen Later Oct 9, 2022 20:57

We just finished hearing about Operation Askari, and a quick note. I said that the Eland armoured would no longer be used for cross -border operations after Askari, but that's incorrect. A listener who was on board an Eland much later in 1987 explained how he was part of an operation called Firewood, where the Eland was used to head across the cutline once more. Apologies for that, and thanks Ian for the correction. FAPLA and the SADF were conducting patrols together as part of the Joint Monitoring Commission or JMC setup after the signing of the Lusaka Agreement in February 1984 – a precursor to a full cease fire. The reality was neither the South Africans nor the Angolans were going to adhere to the agreement terms Pretoria continued to support UNITA, while FAPLA after an intial period of seemingly trying to impose discipline on SWAPO, gave up and allowed their PLAN fighters to continue infiltrating Ovambao. SWAPO mortared the JMC joint patrols a number of times and firefights had developed through March so I'm sure some of the Angolan soldiers were feeling just a tad schizophrenic. Still, the main JMC officials – both the South Africans and the Angolans – gave the impression to each that they were attempting to make this whole cease-fire known as the Lusaka Agreement work. While the SADF and FAPLA were trying to find themselves, the Recces hadn't stopped special operations. In early 1984 and despite discussing land-based cease-fires, the SADF continued to focus on seaborne ops. Their specops operators, the Special Forces were instructed to investigate the destruction of the main water plant supplying the Angolan capital Luanda. This facility was on the south bank of the Bengo River at Quifangonda - Operation Bouganvilia was born.

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Episode 74 – FAPLA/SADF joint patrols hit a wobble & Recce Op Bouganvilia