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In this episode of the Epigenetics Podcast, we talked with Giacomo Cavalli from the Institute of Human Genetics in Montpellier about his work on critical aspects of epigenetic regulation, particularly the role of Polycomb proteins and chromatin architecture. We start the Interview by talking about Dr. Cavalli's work on Polycomb function in maintaining chromatin states and how it relates to gene regulation. He shares insights from his early lab experiences, where he aimed to understand the inheritance mechanisms of chromatin states through various models, including the FAB7 cellular memory module. The discussion uncovers how Polycomb proteins can silence gene expression and the complex interplay between different epigenetic factors that govern this process. Dr. Cavalli also addresses how he has investigated the recruitment mechanisms of Polycomb complexes, highlighting the roles of several DNA-binding proteins, including DSP-1 and GAGA factor, in this intricate regulatory landscape. He emphasizes the evolution of our understanding of Polycomb recruitment, illustrating the multifactorial nature of this biological puzzle. As the conversation progresses, we explore Dr. Cavalli's fascinating research into the three-dimensional organization of the genome. He explains his contributions to mapping chromosomal interactions within Drosophila and the distinctions observed when performing similar studies in mammalian systems. Key findings regarding topologically associated domains (TADs) and their association with gene expression are presented, alongside the implications for our understanding of gene regulation in development and disease. References Déjardin, J., Rappailles, A., Cuvier, O., Grimaud, C., Decoville, M., Locker, D., & Cavalli, G. (2005). Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1. Nature, 434(7032), 533–538. https://doi.org/10.1038/nature03386 Sexton, T., Yaffe, E., Kenigsberg, E., Bantignies, F., Leblanc, B., Hoichman, M., Parrinello, H., Tanay, A., & Cavalli, G. (2012). Three-dimensional folding and functional organization principles of the Drosophila genome. Cell, 148(3), 458–472. https://doi.org/10.1016/j.cell.2012.01.010 Bonev, B., Mendelson Cohen, N., Szabo, Q., Fritsch, L., Papadopoulos, G. L., Lubling, Y., Xu, X., Lv, X., Hugnot, J. P., Tanay, A., & Cavalli, G. (2017). Multiscale 3D Genome Rewiring during Mouse Neural Development. Cell, 171(3), 557–572.e24. https://doi.org/10.1016/j.cell.2017.09.043 Szabo, Q., Donjon, A., Jerković, I., Papadopoulos, G. L., Cheutin, T., Bonev, B., Nora, E. P., Bruneau, B. G., Bantignies, F., & Cavalli, G. (2020). Regulation of single-cell genome organization into TADs and chromatin nanodomains. Nature genetics, 52(11), 1151–1157. https://doi.org/10.1038/s41588-020-00716-8 Related Episodes BET Proteins and Their Role in Chromosome Folding and Compartmentalization (Kyle Eagen) Long-Range Transcriptional Control by 3D Chromosome Structure (Luca Giorgetti) Epigenetic Landscapes During Cancer (Luciano Di Croce) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
In this episode of K9's Talking Scents, host Cameron Ford engages with Todd Wilber from Precision Explosives to discuss the intricacies of explosives, odor prints, and their applications in training detection dogs. The conversation delves into the science behind odor absorption, the importance of surface area in training aids, and the safety considerations when handling hazardous materials. They also explore the debate surrounding the use of Kong toys in detection training and innovative solutions for integrating scent into training tools. This conversation delves into the intricacies of dog scent detection, focusing on various training methods, the implications of 3D printing in creating training aids, and the evolving landscape of bomb detection. The speakers discuss the importance of adapting training to current threats, the effectiveness of different detection materials, and the necessity of realistic training scenarios to prepare dogs for real-world applications. In this conversation, Todd Wilber and Cameron Ford delve into the complexities of explosive detection, focusing on the training of bomb detection dogs and the various types of explosives they may encounter. They discuss the importance of understanding different explosive materials, the challenges posed by new homemade explosives like TATP and R-Salt, and the critical communication needed between dog handlers and bomb technicians. The conversation also highlights the risks associated with dual-purpose detection dogs (Gun and Explosive) and the need for specialized training to ensure safety and effectiveness in the field.Contact Todd Wilbur at http://www.pre-exp.comSponsors:Getxent: Purchase blank or odor soaked tubes at http://www.getxent.com or at http://www.pre-exp.comMichael Ellis School: The only place to get authentic Michael Ellis videos *Michael's Version and training with Michael Ellis is at his website http://www.michaelellisschool.com Ford K9 for all things Detection Dogs and to find webinars, seminars and online classes go to http://www.fordk9.comStratascope: We develop custom, comprehensive security postures for each client. Contact our event operations experts today to learn more about our process and how we can secure your next event. http://www.stratascope.com Chapters00:00 Introduction to Explosives and Precision Explosives02:11 Understanding Odor Prints and Their Applications06:01 The Science Behind Odor Absorption and Release10:00 Best Practices for Using Training Aids12:00 Documenting Training with Odor Aids16:05 Exploring the Role of TADs in Training19:47 Safety Considerations with Hazardous Materials24:08 The Debate on Kong Toys in Detection Training28:04 Innovations in Scented Training Tools31:23 Understanding Dog Scent Detection33:03 The Rise of 3D Printing in Detection Training35:54 Evaluating Electronics Detection Methods38:52 Innovations in Bomb Detection Training46:56 Adapting to Evolving Threats in Bomb Detection55:59 Creating Realistic Training Scenarios01:07:16 Explosive Pairings and Training for Detection01:12:36 Understanding Smokeless Powder: Single vs Double Base01:14:17 Hazardous Device Mixtures and Training Considerations01:18:36 TATP and HMTD: Emerging Threats in Explosives01:21:24 The Explosive Train: Key Components for Bomb Dog Handlers01:24:31 Communication Between Handlers and Bomb Technicians01:27:10 Invisible Bombs: Concealment Techniques and Challenges01:32:02 R-Salt: A New Homemade Explosive01:35:58 The Dual Role of Bomb and Firearms Detection Dogs
Charecterizing selected livestock markets structure in Northern Nigeria and their potential role for transmission of FMD and other TADs
Orthodontist Dr. Claudia Pinter practices in Vienna, Austria and is known for her clinical excellence with aligners as well as her passion for orthodontic education. On this episode, you’ll learn about: Claudia’s early life in Austria and her unique journey into the specialty of orthodontics The importance of clinical photography as a tool for case reflection and improvement Claudia’s expertise with Spark Aligners by Ormco and why she prefers their system How she incorporates cosmetic bonding, laser gingivectomies, and TADs to enhance treatment outcomes Claudia’s tips for content creation on platforms like YouTube and Instagram Recorded July 13, 2024, at the Renaissance Ft. Lauderdale West Hotel in Ft. Lauderdale, FL. Generous support for this podcast comes from Solventum & the Journal of Clinical Orthodontics (JCO). Illuminate Spotlight - Isoglide Eruption Spring Illuminate Exclusives: Journal of Clinical Orthodontics (JCO)10% off a new subscription to the JCOPromo code: POD Mother of Pearls Conference (MOPC)October 10th-12th, 2024 in Scottsdale, AZ$100 off Doctor or Team Member RegistrationPromo code: ILLUMINATEExpires 9/15/2024 Musical Tributes:‘Black Coffee’ by Sonny Burke
Fala, galera! No episódio de hoje, temos o prazer de receber Elomar, formado em TADS desde 2014 e atualmente atuando como Engenheiro de Negócios em Nova York. Elomar começou sua jornada no IFRN em 2005, cursando Técnico em Informática, e desde então tem acumulado experiências valiosas em diversas empresas. Nos últimos cinco anos, ele tem se destacado em uma big tech. Participações: Elomar Ruan Thales Edição e Mixagem: Tads Pelo Mundo Vitrine: Pedro Maure Siga nossas redes sociais para mais conteúdos incríveis! YouTube: Dissonância - YouTube Instagram: @dissonanciapodcast TikTok: @dissonanciapodcast --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
Andrew Chang Orthodontist Andrew graduated with his BDS in Sydney in 1999 and then pursued specialist training where he received a DClinDent in Orthodontics from the University of Adelaide in 2008. In this episode we learn a about Andrew's origin stories, an introduction to the realm of temporary anchorage devices (TADs) and how they can provide more non-surgical options for tooth movements, and current trends in orthodontic technology, navigating the orthodontic journey and when to best discuss aesthetic concerns and options in conjunction with orthodontic treatment. Check out our website: cpdjunkie.com.au #dentalCPD #dentistry #australiandentist #dentistryaustralia #dentalCE #continuingeducation #photography #radiology #prosthodontics #implants #endodontics #sleepapnoea #aestheticdentistry #oralsurgery #orthodontics #2023events #dental #dentalschool #dentistrystudent #australia #sydney #melbourne #dentalevents #dentaleventsaustralia #dentaleducation
Dive into the dynamic world of pickleball with the Alpha Pickleball Podcast as host TADS sits down with pro player Wes Gabrielsen. From his humble beginnings playing with wooden paddles to competing internationally, Wes shares his journey and insights into the sport. Discover how he developed his unique playing style, his role as a coach for MLP teams, and his vision for the future of pickleball. Gain valuable tips on strategy, team chemistry, and training camps straight from the court. Whether you're a seasoned pro or a curious beginner, this episode serves up a volley of knowledge that'll elevate your game to alpha levels.
Fala galera! A convidada de hoje é Astrogilda formada desde de 2020 em TADS e hoje atuando como analista de requisitos. Participações: Astrogilda, Ruan e Thales. Edição e Mixagem: Tads Pelo Mundo Vitrine: Pedro Maure Siga às nossas redes! Youtube - Dissonância - YouTube Instagram - Dissonância podcast Tiktok - @dissonanciapodcast --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
Fala galera! Os convidados para dar início ao ano são Simei e Rebeca, compartilhando conosco sua trajetória no curso de TADS e suas experiências profissionais. Ouça também: Dissonância 52 - "2023 em Filmes: E o Que vem por aí em 2024" Participações: Rebeca, Ruan, Simei e Thales. Edição e Mixagem: Tads Pelo Mundo Vitrine: Pedro Maure Siga às nossas redes! Youtube - Dissonância - YouTube Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
Fenerbahçe-Galatasaray derbisini Karalama Defteri 130. bölümde tüm detaylarıyla konuştuk. Tadsız Tuzsuz Derbi Arda Kardeşler Hakemliği Bırakmalı Barış Alper Sol Bek Mevkisine Isınıyor Pozisyonlar Kerem Demirbay'dan Transferler Bekleneni Veremiyor Moritz Volz Gerçekleri 5 Gün Sonra Bir Derbi Daha
Join me for a summary looking at miniscrews, looking at where the answer to successful TAD placement lies, in research or clinical practice. The reasons for higher failure rates than others with TADs was explored through 3 key factors; insertion torque, site selection and root proximity. Evaluation of both scientific and clinical processes were described by Sebastian Baumgartel at the British Orthodontic Conference, as the Northcroft lecture. Is torque a factor in TAD success? Torque study – compression during insertion Motoyoshi 2006 · High torque – 60% · Low torque = 72% · Medium torque – 92% Understanding · Low torque = low compression, low primary stability - early failure as not engagement with screw · High torque = high compression, early success, but greater resorption after insertion, remodelling results in a resorption process · Medium = best of both = sufficient compression for primary stability, not high enough to cause resorption remodelling Ideal · Ideal torque range – 10 Ncm Shantavasinkal 2016 o Study of buccal tads · Sebastian's empirical experience between 10-25Ncm depending on site Rules: · Aim for medium torque · Target 10Ncm · Exceed 10Ncm on palate acceptable What is the best site for TAD insertion? Keratinised gingiva · Evidence - states no difference Lim 2009, Chen 2008, Park 2006, Cheng 2004 · Non Keratlised – depends on mobile or non mobile, with non-mobile higher success rate Viwattanatipa 2009 · 2mm apical to muco-gingival junction o zone of opportunity Target zones and site o No roots o Consistent cortical bone o More tolerant to higher torque o Attached gingiva with low mobile mucosa Is there ideal bone? · = if ideal torque = ideal cortical plate thickness § 1-1.5mm cortical plate thickness · CBCT can be overkill, using research sites for average sites Ideal site: – 1st premolar region (transverse) Sebastian 2009 – 2 mm away from mid-palatal suture o = creates ideal zone ‘Mx1' Evidence of site selection success · 98% Vs buccal 71% Houfar 2017 · 84% Trainee success Sebastian 2020 · Success of Sebastian anterior palate 100%, maxillary buccal lowest 85% Does root proximity influence TAD success? · Not just contact with roots, but proximity to root also causes failure Kuroda 2007, Asschericks 2008, Chen 2008 Understanding o Increase root and PDL proximity = bone stress increases = increase bone turnover = increase failure of TAD · 4mm interradicular distance needed (depending on size of tad) to achieve 1 mm clearance from roots · Most buccal sites have less than 4mm (resolve through diverging roots, or sites with no roots) What happens if TADs fail and we try again? – Secondary insertion success o 58% (reduced by 33%) Park 2006 o 44.2% (reduced by 36%) Uesugi 2017 o 58.1% buccal (reduced by 21%), 88.9% palatal (increased by 4%) Uesugi 2018 § Uesugi 2018 showed buccal failure increases for secondary insertion, but palatal insertion increases success For more education see Sebastian's TAD course: https://tadchallenge.com/tad-certification-course I have no financial interest
De SMIB X TNO family schuift aan bij Bundy om het te hebben over stijl, culture, het opkomende SMIB X TNO Fest en natuurlijk of die boys ook barbecueën in de achtertuin, toch Eben? Chap jij libbe? De hele fam is aanwezig. Ray Fuego, Nnelg, Tads, Professor Soortkill en de natuurlijk rest. Vier uur lang genieten, Hef. Kaartjes voor SMIB X TNO Fest haal je hier: https://smibtnofest.nl/products/smibt... Wil je nieuwe episodes al op zaterdag checken? Of luisteren naar exclusieve 1-op-1 gesprekken? Meld je aan op: https://rookworst.nl/subscribe
In this episode of the Epigenetics Podcast, we talked with Alistair Boettiger from Stanford University about his work on the analysis of 3D chromatin structure of single cells using super-resolution imaging. Alistair Boettiger and his team focus on developing advanced microscopy techniques to understand gene regulation at the level of 3D genome organization. They have developed Optical Reconstruction of Chromatin Architecture (ORCA), a microscopy approach to trace the 3-dimensional DNA path in the nucleus with genomic resolution down to 2 kb and a throughput of ~10,000 cells per experiment. These methods enable the identification of structural features with comparable resolution to Hi-C, while the advantages of microscopy such as single cell resolution and multimodal measurements remain. References Boettiger, A., Bintu, B., Moffitt, J. et al. Super-resolution imaging reveals distinct chromatin folding for different epigenetic states. Nature 529, 418–422 (2016). https://doi.org/10.1038/nature16496 Bogdan Bintu et al., Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells. Science 362, eaau1783 (2018). DOI:10.1126/science.aau1783 Mateo, L.J., Sinnott-Armstrong, N. & Boettiger, A.N. Tracing DNA paths and RNA profiles in cultured cells and tissues with ORCA. Nat Protoc 16, 1647–1713 (2021). https://doi.org/10.1038/s41596-020-00478-x Rajpurkar, A.R., Mateo, L.J., Murphy, S.E. et al. Deep learning connects DNA traces to transcription to reveal predictive features beyond enhancer–promoter contact. Nat Commun 12, 3423 (2021). https://doi.org/10.1038/s41467-021-23831-4 Tzu-Chiao Hung, David M. Kingsley, & Alistair Boettiger. (2023). Boundary stacking interactions enable cross-TAD enhancer-promoter communication during limb development. BioRxiv, 2023.02.06.527380. https://doi.org/10.1101/2023.02.06.527380 Hafner, A., Park, M., Berger, S. E., Murphy, S. E., Nora, E. P., & Boettiger, A. N. (2023). Loop stacking organizes genome folding from TADs to chromosomes. Molecular cell, 83(9), 1377–1392.e6. https://doi.org/10.1016/j.molcel.2023.04.008 Related Episodes Hi-C and Three-Dimensional Genome Sequencing (Erez Lieberman Aiden) Unraveling Mechanisms of Chromosome Formation (Job Dekker) Biophysical Modeling of 3-D Genome Organization (Leonid Mirny) Contact Epigenetics Podcast on Twitter Epigenetics Podcast on Instagram Epigenetics Podcast on Mastodon Active Motif on Twitter Active Motif on LinkedIn Email: podcast@activemotif.com
Fala galera! O convidado dessa semana, Lavínia Medeiros, compartilha conosco sua trajetória no curso de TADS, experiências profissionais e oportunidades internacionais. Participações: Lavínia Medeiros, Filipe Oliveira e Thales Azevedo. Edição e Mixagem: Pedro Maure Vitrine: Filipe de Oliveira Siga às nossas redes! Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast Youtube - Dissonância - YouTube --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
This is a conversation with Tad Hargrave about … ✨ Why it's okay to feel uncomfortable about marketing ✨Tads career path ✨Lacking confidence or competence? ✨The best type of marketing ✨3 stages of business
Fala galera! O convidado dessa semana, Sedir Morais, compartilha conosco sua trajetória no curso de TADS e seu papel como pesquisador do LAIS, direito do Japão! Participações: Sedir Morais, Filipe Oliveira e Thales Azevedo. Edição e Mixagem: Pedro Maure Vitrine: Filipe de Oliveira Siga às nossas redes! Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast Youtube - Dissonância - YouTube --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.23.529799v1?rss=1 Authors: Tuulari, J. J., Pulli, E. P., Kataja, E.-L., Perasto, L., Lewis, J. D., Karlsson, L., Karlsson, H. Abstract: Background: Childhood maltreatment exposure (CME) and related trauma could be considered some of psychiatry's greatest public health challenges. CME and early adversity have been associated with increased amygdala volume in exposed individuals. Emerging evidence implies that CME could also affect prenatal development of the offspring. Methods: As part of the FinnBrain Birth Cohort Study, we measured bilateral amygdala volumes from MR images in 76 healthy infants at 2 to 5 weeks of gestation corrected age and obtained the Trauma and Distress Scale (TADS) questionnaire from both parents. The associations between neonatal amygdala volumes and TADS scores were examined in stepwise regression models. Results: We found that maternal CME associated positively with infant left amygdala volume (p = .045) while the positive association for the paternal trauma score was only marginally significant (p = .099). Similar associations were not observed for the right amygdala. In the exploratory analyses, we used age ranges (0 to 6, 7 to 12, and 13 to 18 years) as estimate of the timing of the CME and included all three time points from both parents using left amygdala volume into the stepwise regression models. We found that maternal TADS scores from 13 to 18 years of age associated positively with infant left amygdala volumes (p = .008). Correspondingly, paternal TADS scores from 0 to 6 years of age associated positively with the infant left amygdala volumes (p = .014). Conclusions: Our link the infant offspring amygdala volume with parental CME with some agreement with prior findings, and they also imply links paternal CME to infant amygdala volumes. Amygdala is one of the key brain structures associated with both early life exposures and later psychiatric health, which makes it crucially important to elucidate both the underlying mechanisms and the later relevance of these associations in future studies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Jason was joined by the regular cast members in Cxrn, Tads and IB and we ran through this weekend's SCOUT UK derby between Liverpool vs Chelsea and Arsenal vs Man Utd as well as the remainder of games amongst the top sides. If you've enjoyed the episode, leave us a like, comment and subscribe/follow our podcast on Spotify, Apple Podcasts and YouTube! Don't forget to use the #SCOUTUK hashtag to join in the conversation on Twitter. Follow us on our social platforms too: Twitter: @SCOUTUK, @cxrnelius1, @suanzreal, @txdss__ & @ibjugg Instagram: @scout.uk YouTube: SCOUT UK TikTok: scoutukpodcast
Fala galera! O convidado dessa semana, João Lucas, compartilha conosco sua trajetória como Tecnólogo em Analise e Desenvolvimento de sistemas, seu trabalho em projetos de desenvolvimento e atualmente gestor de equipes de suporte. Participações: João Lucas, Ruan e Thales Azevedo. Edição e Mixagem: Pedro Maure Vitrine: Filipe de Oliveira Siga às nossas redes! Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast Youtube - Dissonância - YouTube --- Support this podcast: https://podcasters.spotify.com/pod/show/dissonancia/support
Lower arch missing lower 2nd premolars Hemisection lower E – distal half – Old school Allow mesial drift of 6s, L4s do not distally tip, important in class 2 cases Use mesial aspect for anchorage if ankylosed Remove remaining Other options TADs 30% failure in the mandible in Caucasian Herbst Mini-plates – very evasive But hemisection is simple Gingivectomy After extrusion of impacted tooth, need for gingivectomy Orthodontists should learn as common need Process Scan Plan a gingivectomy guide Laser or electrosurgery for gingivectomy Cant and TADs adult cases are the future of orthodontics, more challenging RHS>> Gincevectomy LHS>> extrusion using TADs TAD – opencoil to bracket on the tooth, and aligner to guide the tooth, cover incisal edges only And few aligners Patient did not want perfect result Space closure and TADs Georgios Kanavakis 2014 Space closure and mesial slider 2 x palatal tads SS spring close Mesialization of molars High tech But Space closure can be achieved with timely extractions, such a smissing UEs and extractions with mesial drift.. Less likely lower arch, miniplates used to mesialise Expansion Digital planning Digitally decompensate the lower arch. MARPE Changes to the midface through MARPE Hard tissue changes to the midface and nasal complex Caution in use, for selective cases only, and critical in use SARPE Indicated due to resistance for Maxillary expansion in adults from 3 potential structures Zygomatic buttress, Pterygoid plates, Sutures from the mid face Published 1984 by Andrew Glassman Using a finite element analysis programme, fusion 360, identify the resistance individual to patient Case: Surgical guide to do a small lateral osteotomy under local = future as it is individualized to each patient Hybrid treatment brackets Vs aligners Class 2 correction Change from fixed to aligners with Onyx Ceph planned wings for class 2 correction – like functional appliance Problems Distalisation with Miniscrews Later on posterior crowding of 2nd molars and risk anterior recession Fracture of palatal appliance Failure at welding point between expander and abutment Can stop people using designs Solution print 1 piece appliance CADCAM Overuse TAKE HOME MESSAGE BY ME FROM THE LECTURE Sometimes effort is not equal the benefit so always evaluate your benefit Always assess your outcome and see if technology you invested in worth it Orthodontists are Dentists and should do some gingival contouring and temporaries ..etc Always match arch before and after treatment and maintain your arch form Future is Hybrid Therapy … using strength of both aligners and fixed braces
Fala galera! O convidado dessa semana, Luiz Sérgio, compartilha conosco sua trajetória no curso e experiências no trabalho! Ele já trabalhou de empresas privadas a grandes empresas públicas, como Petrobras e Dataprev! Participações: Filipe de Oliveira, Luiz Sergio, Pedro Maure e Thales Azevedo. Edição e Mixagem: Dissonância Vitrine: Filipe de Oliveira Siga às nossas redes! Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast Youtube - Dissonância - YouTube --- Support this podcast: https://anchor.fm/losersqg0/support
The aim (focus) of this poster is to consider digital transformations of Analog Geography Hunting Grounds Maps (AGHGMs) (image 1) as well opportunities of introduce digital hunting grounds maps (DHGMs) in veterinary surveillance, monitoring, control programme for wildlife populations. Geographical Information System (GIS) as a computer based analyzing system displaying digital data with spatial sets. Spatial veterinary epidemiology (SVE) enabled the spatial/location of TADs and FAST diseases to aim identify the susceptible populations (domestic and wildlife) and epidemiological risk factors. Epidemiologic surveys calculate the disease incidence to facilitate the disease investigation and to frame preventive measures.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.16.512276v1?rss=1 Authors: Tuulari, J. J., Kataja, E.-L., Karlsson, L., Karlsson, H. Abstract: Background: Childhood maltreatment exposure (CME) can lead to adverse long term consequences for the exposed individual. Emerging evidence suggests that the long term effect of CME may be transmitted across generations, starting already during prenatal development. Methods: In this study, we measured brain grey and white matter volumes from MR images in 62 healthy neonates at 2 to 5 weeks of gestation corrected age and obtained Trauma and Distress Scale (TADS) questionnaire data from both parents. Results: We found that paternal CME associated positively with neonate supratentorial grey matter volumes while the association for the maternal TADS scores was not statistically significant. Maternal prepregnancy BMI associated with supratentorial white matter volumes, but not with parental CME. Conclusions: We are the first to report that paternal CME is linked with variation in newborn grey matter volume. Our results imply an intergenerational transmission of paternal CME to offspring. Elucidating the later relevance of these associations and mechanisms involved remains an enticing avenue for future studies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
What goes wrong with MARPE? Audrey Yoon Join me for a lecture summary from this years AAO by Audrey Yoon. Don't Make the Same Mistake I Did/ MARPE Complication. Success MARPE Overall separation: 87.8% Success rate of sutural separation: (Jeon 2021) · 61.05% in male · 94.17% in female · Average expansion: 7.8 ± 2.4 mm. Variation with age and gender MARPE efficacy = Achieved Vs planned expansion · Greater negative correlation with age in general o More male than female o Planned Vs achieved a. 20 years old = 1:1 M:F b. 30 years old = 0.5:1 : 0.8:1 c. 40 years old = 0! : 0.6:1 BUT NO DATA – extrapolation No relationship with bicortical engagement Asymmetric expansion · = 50% of cases ANS level greater than 1mm · 27% Greater than 2mm at ANS · Severe: Similar to tripod fracture · Causes of asymmetry Kim 2019 · Nasal-maxillary suture opening / remain closed · 30% of case unilateral opening of suture SARPE = 3-13% asymmetric expansion Williams 2012, Smeets 2020 Pain · 45% report pain · 19% Around band of 1st maxillary molar band · 10% headaches Gingival inflammation · 83.9% of patients · Design = flush o Change to 1mm from palate and arms 3mm from palate = reduce · Greater inflammation in retention o Possibly due to palatal vault relapse and therefore TADs imbed in palate Breakages · 10% · Usually guide rod / arm Rare: Loss of vitality 2% · Required RCT maxillary incisors (SARPE 4.5%) Fractures - potential tripod fracture Infra-orbital numbness · Temporary numbness 6 weeks · 3 cases · Management · Turn backwards slowly · Facial massage / myofascial · Folate, Vit b – aid nerve regeneration Hearing loss · Zygomatic arch = hearing loss temporary, tetanus, trismus Unexplained tears · Lateral orbital rim = sagging eyeball, lacrimal gland Popping in the ear Lateral pterygoid fracture · Click and popping to the ear – cheek shooting pain · Lateral pterygoid plate fracture – asymmetric expansion Consent Audrey Yoon – youtube patient instruction video / leaflet Growing consent Audrey Yoon paper AJODO clinical companion – open access A retrospective analysis of the complications associated with miniscrew-assisted rapid palatal expansion` Audrey Yoon 2022
Fala galera! O convidado dessa semana, fala um pouco de suas experiências com o curso de Análise e Desenvolvimento de Sistemas (TADS), direto de São Paulo. Falamos sobre mercado, Interâmbio, PDS e muito mais! Participações: Filipe de Oliveira, Luis Felipe e Thales Azevedo. Edição e Mixagem: Dissonância Vitrine: Filipe de Oliveira Siga às nossas redes! Instagram - www.instagram.com/dissonanciapodcast/ Tiktok - http://tiktok.com/@dissonanciapodcast Youtube - Dissonância - YouTube --- Support this podcast: https://anchor.fm/losersqg0/support
The occurrence of transboundary animal diseases (TADs) causes serious socio-economic consequences, as it affects productivity, welfare, livelihoods, food security and trade. Communities that mainly depend on livestock are the most vulnerable, and the consequences of TADs may vary within and across countries/areas depending on the disease and its spread, the structure of the livestock sector, the social context and related control strategies. Therefore, it is often difficult to provide systematic estimates of their economic impact. The objective of this study was to develop a tool for the economic evaluation of any TADs affecting ruminants, by adapting and validating the already available tool for swine disease outbreaks, known as OutCosT-Pig.
Mizoram, a mountainous state nestling in the southern tip of the northeastern region of India, remains in constant threat of TADs, affecting the growth of livestock value chains. In recent years, the State suffered from Porcine Reproductive and Respiratory Syndrome (PRRS) outbreak. Subsequently, the first outbreak of African Swine Fever (ASF) emerged and is continuing. The existing initiatives within the State primarily focus on emergency management cycle stages, viz. prepare, prevent, and detect. The expected outcome of the study is policy initiatives to enable the commissioning of a GIS-based decision support system (DSS) to support the implementation of action plans related to the 'response' and 'recover' phases.
Join me for a summary of Björn Ludwig's lecture exploring Miniscrew Assisted Rapid Palatal Expansion (MARPE) and Surgically Assisted Rapid Palatal Expansion (SARPE). Björn described how MARPE works, aspects of design and his clinical process. Effects of MARPE Parallel opening of suture 2mm greater at 6 region than RME (S/R Krusi 2019) Facial changes Widens Zygoma Nasal base expands Changes to the orbit – no significant but beware Brutally evasive! No periodontal side effects with MARPE (limited evidence) S/R Vidalon 2021 RME Vs bone borne, hybrid = bone borne no dental side effects: Canan 2017 Age MARPE Vs RME Age up to 11, no difference in outcomes Bazargani 2021 Retention after MARPE At 7 months: suture has not fully remodelled Retention is needed for 1 year to allow full remodelling Type of retainer TPA does not maintain bony changes Prado 2014 TPA with TADs = prevent bony relapse Expansion rate of MARPE Fast Vs slow bone borne Fast (2-3 x activation per day) Vs slow (2 activations per week) Slow expansion MARPE: Sutural opening still occurs Pulver 2016 (Rabbit study) No diastema Activation process: Force controlled polycyclic activation Activation occurs if the force is 500g, key indicates activation Winsauer 2021 Airflow Increase in airflow with MARPE White paper from AJODO on OSA – limited evidence Our job is to get rid of crossbites NOT to resolve OSA MARPE effective at resolving crossbite S/R: Kapetanović 2019 MSE reduce OSA: Brunetto and Moon 2022 Björn considered a good side effect, not the main cause Class 3 RME most effective in class 3 cases Alt-Ramec Eric Liou 2005 3 x day = maxilla moves downwards and forwards due to position of buttress Facemask Facemask in the night, and class 3 elastics in the day A point advance 3mm: MARPE + facemask study: Maino 2018 Realistic ½ unit correction – borderline correction SARPE Vs MARPE SARPE mainly changes maxilla, maintains aspects of midface MARPE changes to midface Take home messages Hi tech is good but low tech is key No body said it was easy, and orthodontics is not easy For more information see Benedict Wilmes guest blog on Kevin O'Brien's Orthodontic Blog
In this episode, I am joined by Dr. Nicole Scheffler. She is one of the amazing speakers lined up for the Orthopreneur Summit in September.Dr. Nicole Scheffler received her dental and orthodontic training from the University of North Carolina – Chapel Hill. She practices full-time in Boone, North Carolina. She lectures a lot on closing anterior open bites all over the country and the world.Back in the year 2000, when nobody was doing TADS in the US, Dr. Nicole went to Belgium to learn how they were placing TADS and how the patient experience was. She came back and approached ORMCO, and that's how VectorTAS came about.Nicole recommends closing open bites with TADS in conjunction with an open bite splint to intrude the posterior because it's just as stable as jaw surgery.We also talk about creating a vibrant office culture where staff want to come to work. This is important as we all know getting and keeping dental assistants who are the right fit is key to the success of your practice.Tune in!Key Takeaways- Dr. Nicole Scheffler's background (01:38)- The pedo-ortho relationship (06:48)- How Dr. Nicole got into open bites (10:30)- Orthognathic surgery (14:31)- The etiologies for an open anterior bite (16:14)- Closing open bites with aligners or TADS? (20:27)- How to find good assistants for your practice (22:53)- Advanced Dental Assisting Academy (24:33)Additional Resources
Join me for a summary of Akram Alhuwaizi's lecture on MARPE – Miniscrew assisted rapid palatal expansion. This summary explores MARPE from a clinical aspect, assessing the advantages and disadvantages, followed by a case discussion of success and failure, a discussion of MSE and lessons learned for designing MARPE. The full lecture is available on Akram's youtube channel: Maxillary Skeletal Expansion using MARPE from A to Z (Updated) - YouTube Introduction Purpose of expansion Correction of crossbite Creating space Pre myofunctional treatment Widening smiles Methods available Removable appliance Quad Helix Rapid Maxillary Expander RME Surgically assisted Rapid Palatal Expansion SARPE Expansion methods Ideal features of expansion appliances are to achieve bodily movement, minimal compliance required from the patient, applicable to a range of ages and straightforward for patients MARPE experience Case 1 Attended Peter Ngan lecture Arab conference Surgical case requiring expansion – 2019 4 palatal TADs FAILIURE – TADs moved, one got embedded into the palatal tissue, no significant expansion occurred Cause of failure Hyrax position: Too posterior = near to Pterygo palatine suture and the zygomatic buttress which causes more resistance to the expansion No guiding arms, greatert risk of dental movements but they help in seating of the appliance Lack of guiding arm allowed rotation of the device by failure of only one TAD. TADs Length: Short: Ideally bi-cortical engagement to avoid bending and increase retention Appliance design There was a play between the TAD and the device Lab fabricated loops, not precision fit Case 2 Design Used 2 TADs 2mm D/12mm L Guiding arms to the 1st molars Hyrax more anterior Good fit abutment / screw and expander Longer screws – bicortical engagement Younger patient and female Successful palatal expansion
Join me for the next interview in orthodontic, with video! James is a private orthodontist from Perth Australia, a clinician with a passion to share, teach and learn. James has authored a chapter on 3D diagnosis and treatment planning and has 22,000 followers on Instagram with 625 posts relating to orthodontics on a variety of topics including biomechanics, TADs, orthodontics and restorative / periodontal management We get to hear of James' thoughts on social media Vs conventional orthodontic education, his thoughts on biomechanics, and advice for orthodontists. Facebook: @jamesandrewsortho Instagram: @dr.jamesandrews Youttube video
Orthodontist Dr. Sebastian Baumgaertel is a renowned expert on the use of orthodontic temporary anchorage devices (TADs) or mini-screws. On this episode, you will learn about: *Sebastian's early life in Germany and what led him to the United States *Biomechanical indications for TADs to achieve skeletal anchorage *Ideal locations for placing TADs for better success rates *Best practices for placing TADs in an orthodontic office *Sebastian's variety of hobbies & interests Recorded August 27, 2021 in Cleveland, OH. To hear exclusive outtakes from this episode, please head over to www.illuminateorthopodcast.com or the SoundCloud app. Generous support for this podcast comes from LightForce Ortho & Fishbein Fundamentals.
Join me for the summary of key lectures from the final day of this year's American Association of Orthodontics Summer Meeting 10 key lectures are covered in this podcast from day 3 of the AAO meeting, on the topic of TADs, Carriere, Orthognathic surgery first, Skeletal TAD expansion, orthodontic uncertainty Speakers:Jay Bowman, Kevin O'Brien, Luis Carriere, Bjorn Ludwig, Maschos Papadopoulos, Beom Kim, Jungi Sugawara Individual lecture podcasts are available in the description from the website www.orthoinsummary.com Lectures titles: 1. TADs- Keeping it simple while being successful Sebastian Baumgaertel 2. Uno, Dos, Tres/ All the Screws in the Same Place Jay Bowman 3. Class II Minimum-Touch Approach in an Evolving Orthodontic World Luis Carriere 4. The Management of Occlusal Plane with Extra-Alveolar Miniscrews. Marcio Almeida 5. TAD Supported Space Closure in Agenesis Cases Bjorn Ludwig 6. Maxillary Molar Distalization with Mini-screw Implant Supported Appliances Maschos Papadopoulos 7. Navigating Complexities in Surgical Orthodontic Cases Jerry English & Kurt Kasper 8. Tooth Bone vs Tissue Bone MSE Does it matter? Beom Kim 9. Less Invasive Surgery First Approach Jungi Sugawara 10. Orthodontic uncertainty. Research, core outcomes and snake oil. Salzmann Lecture Kevin O'Brien
AAO Virtual Annual Session June 2021 Day 2 Join me for the summary of key lectures from this year's American Association of Orthodontics Summer Meeting 14 key lectures are covered in this podcast from day 2 of the AAO meeting, on the topic of Maxillary Skeletal Expansion, TADs, Bone plates, Carriere appliance, Digital Orthodontics, Phase 1 treatment, Facemask, Aligners, Speakers: Hugo De Clerck, Jonathan Nicozisis , Carlos Flores-Mir, Jason Cope, James McNamara, Peter Ngan, Benedict Wilmes, Stella Chaushu, Brandon Owen, Juan Fernando Aristizabal, Roberta Lione, Tung Nguyen Individual lecture podcasts are available in the description from the website www.orthoinsummary.com Lectures titles: 1. Long-term evaluation of class 3 orthopedics using skeletal anchorage. Tung Nguyen 2. Growth Modulation by class 2 and class 3 orthopedics Hugo De Clerck 3. When you play the games of Thrones, you win, or you die. Is there a middle ground Carlos Flores-Mir 4. Can Changing the Transverse Dimension Improve the Quality of Orthodontic Treatment in Children? Dr. Roberta Lione 5. How To Become An In-House Aligner Power House. Jason Cope 6. Carriere 3 Treatment in minimally growing patients- How does it work? James McNamara Management of the Carriere Motion Appliance for Class III Correction in the Mixed and Permanent Dr. Laurie McNamara McClatchey 7. Treatment of maxillary deficiency with facemask and TADs Peter Ngan 8. Maxillary Expansion & Treatment of Class III Malocclusion in the Digital Age Dr. Benedict Wilmes 9. Clear Aligners in Orthognathic Surgery Flavio Uribe 10. Growing and Redirecting the Roots of Impacted Teeth Stella Chaushu 11. Surgery First Combined with CAD/CAM Brackets and 3D Predictions Juan Fernando Aristizabal 12. Clear Aligner Treatment- One Size Does NOT Fit ALL Dr. Clark Colville 13. Efficiencies of Aligner Treatment in Teens and Early Treatment Jonathan Nicozisis 14. The 'How to' Guide of Digital Braces/Teledentistry Brandon Owen Please like and subscribe if you find it useful!
Join me for the summary of key lectures from this year's American Association of Orthodontics Summer Meeting 13 key lectures are covered in this podcast from day 1 of the AAO meeting, on the topic of Aligners, TADs, Miniscrew assisted expansion MSE, Biomechanics, AOB, 3D Metal printing, aging dentition, Forsus Speakers: Chris Chang, Won Moon, Ravi Nanda, Daniela Garib, Brent Larson, Maz Moshiri, Lorenzo Franchi, Lorenzo Franchi, Kenji Ojima, William Dayan, Simon Graf, Lisa Alvetro, Flavia Artese, Jae Hyun Park Individual lecture podcasts are available in the description from the website www.orthoinsummary.com Lectures titles: 1. Simplified Mechanics for Aligners in Treating Complex Cases Dr. Chris 2. The Evolution of Mini-implant Assisted Midfacial Expansion, the Latest Developments and Advanced Applications Won Moon 3. Biomechanics and Force Delivery Systems- Wires to Screws to Plastic Ravi Nanda 2021 Edward H. Angle Award Lecture 4. Aging of the Occlusion- What Should We Know? Daniela Garib 5. Applying Science to Aligner Mechanics and Design Brent Larson 6. Suggestions for Systematic Treatment of Orthognathic Surgical Patients with Clear Aligners Maz Moshiri 7. Jacob A. Salzmann Award Lecture; Efficient and Effectively. Lorenzo Franchi 8. Type of Approach for Biomechanics of Aligner Orthodontics Kenji Ojima 9. Ideal Occlusion is Not Always the Ideal Treatment Plan William Dayan 10. 3D Metal-printed Bone Borne Appliances Simon Graf 11. Tips to Optimize Treatment Results Using Forsus Class II Corrector Dr. Lisa Alvetro 12. Key Factors to Consider when Correcting the Vertical Dimension Flavia Artese 13. Anterior Open Bite Correction- Conventional Treatment vs. TADs Jae Hyun Park
Invisalign: Virtual Orthodontic Summit 2021 Join me for the summary of key lectures from this year's Invisalign UK Virtual Orthodontic Summit meeting 4 lectures are covered in this podcast on the topic of biomechanics and aligners, using tuberosity TADs and troubleshooting with aligners Speakers: John Morton, Willy Dayan, Susana Palma, Graham Gardner Individual lecture podcasts are available in the description from the website www.orthoinsummary.com Lectures titles: 1. Biomechanics of the Invisalign system 2021 John Morton 2. Treating complex aligner biomechanics. Willy Dayan 3. Overcoming difficulties in class 2 correction with TADs in tuberosity and aligners. Susana Palma 4. Monitoring and troubleshooting Graham Gardner The podcast is opinion and may not be 100% accurate or representative of the lecture / speaker, the podcast is not endorsed by an institute or the speaker and is the independent work of Farooq Ahmed and the Orthodontics in Summary team. It is not intended to over-ride or replace the requirement clinicians have in being familiar with the relevant training and guidelines for the treatment they provide #orthodontics #farooqahmed #almuzian #orthodonticsinsummary #aligners, #TADs #tracking #orthodontics #farooqahmed @farooqahmed_orthodontist
Join me for the second interview of 2021 Adith is a Consultant and Assistant Professor in Orthodontics at the University of Puthisastra South Korea, adjunct faculty Professor Chennai India, Co-editor of Kieferorthopaedie journal (International Orthodontics). We get to hear of Adith's journey into using TADs, his one piece of advice to all orthodontists and what questions Adith hopes will be answered in orthodontics, as well as Hollywood Vs Bollywood! Please find the link to Adith's up coming editorial in the AJODO entitled: ‘The Quagmire of Collegiality Vs. Competitiveness' We hear of Adith's thoughts on case reports and where evidence based practice fits in to the unique field of orthodontics
Join me for part 2 where we explore Mohammed's rules on which teeth to extract, anchorage assessment and management, Bonding 2nd permanent molars, elastics and treatment planning adults Vs children Which to extract 4 or 5 o CAT-V principle § C: Clinical condition of the teeth § A: Anterior crowding: 8mm + extract the 4s, 8mm – 5s or 4s § T: Transverse: Lower 5 will help narrow the arch § V: Vertical: Extraction of 5s for high angle cases will improve the overbite Molar outcomes in treatment planning o Non-extraction or extraction of 4 premolars = class 1 o Extraction of 2 upper premolars: Class 2 o Extraction of 2 lower premolars: Class 3 o Extraction of 1stmolars: Ignore them! Will not change the final molar relationship Anchorage o Type A (absolute) No movement of the posterior segment o TADs – HG – extraction pattern o Type B posterior movement moves mesially by 25% o Nance, sectional archwires, intermaxillary elastics, HG o Type C posterior movement moves mesially by 50% o Reciprocal movement of anterior retraction o Type D posterior movement moves mesially by 75% o Anterior anchorage (reverse HG, TADS) o Biomechanics: intermaxillary elastics – 2nd order bends – inverted lower brackets Anchorage loss in the lower arch is less than upper arch · Differential alveolar bone density · differential root surface area · differential Buccolingual width of molar · differential anterior palatal root torques Bonding upper 7s o Don't bond to for anchorage o Bonding results in loss of anchorage due to 7s distally tipped, uprighting results in loss of anchorage Elastics o Elastics = rotation of mandible o Overjet 0.5mm correction per month with class 2 elastics o 1:3 ratio of vertical: horizontal effects o Unilateral intermaxillary elastics in one side only = cant o = Use vertical part time elastics on the other side o Elastic should be stretched 3 times its diameter to give the force Distalisation Rule o Don't expect you can distalize more than 2.5 mm unless you extract 7 OR 8 o Distalization lowers without TADS is very limited Adults Vs growing patients · Growing patient: o Elastics +++ o Distalisation +++ o Functional appliances +++ o Extractions +++ · Adult o Extractions +++ o Elastics ++ o Distalisation +
Join me for part 2 of Adith's lecture looking at the vertical dimension in orthodontics and its management. Part 2 looks at 6 cases with vertical management of impacted canines, the use of TADs including buccal shelf and infrazygomatic TADs. 4th case impacted canine · Avoid continuous archwire as it can cause: o Iatrogenic root resorption o If stubborn canine = greater occlusal side effects · Resolution: TAD opposing arch o Traction hook bonded to canine o 150g elastic from lower TAD to traction hook on upper canine o Providing intermittent forces 5th case scissor bite · Buccal shelf TAD – placed vertically buccal to lower 6-7 · Anterior bite blocks to disocclude · Mechanics: o Buccal movement of molar with powerchain from BS TAD - molar o Intrusion of molar with vertical vector to TAD 6th case cant · TAD x 2, between U2-3 and U5-6 – placed high · 19*25 NITI continuous · Powerchain from TADs to brackets for intrusive force 7th case gummy smile · Posterior TADs in conventional mucogingival junction with vertical vector not likely to achieve clinical improvement. · Require TAD anterior region, and infrazygomatic TAD for retraction and intrusion 8th case class 3 with AOB · Buccal shelf TADs o Powerchain BS to hooks distal to lateral incisors on archwire: § Distalise lower molars § Intrude lower molars § Extrude lower anterior teeth – change to occlusal plane · Extraction of 3rd molars · TADs left in situ in retention in case of relapse. 9th case periodontally compromised patient o 014NT, not all teeth ligated, alternate teeth ligated = increase inter-bracket distance = less force References Venugopal, A., Manzano, P. and Rengalakshmi, S., 2020. A Novel Temporary Anchorage Device Aided Sectional Mechanics for Simultaneous Orthodontic Retraction and Intrusion. Case Reports in Dentistry, 2020. Venugopal, A., 2020. Interarch traction for impacted canines. APOS Trends in Orthodontics, 10(1), pp.60-61. Venugopal, A., Manzano, P., Arnold, J., Ludwig, B. and Vaid, N.R., 2020. Treating a severe iatrogenic gingival exposure and lip incompetence–a challenge worthwhile. International orthodontics.
Join me for part 1 of Adith's lecture looking at the vertical dimension in orthodontics and its management. Part 1 looks at 3 cases with vertical management through TADs, TPAs and a re-visit of the management of the Curve of Spee. 1st case TADs for extraction of 4s case · Without TADs can result in ‘bowing effect' – extrusion of incisors and molars. · TAD placed between the upper 5- 6 root o Direct retraction of the labial segment to the TAD o Ligature wire from TAD to archwire 5-6 region, to prevent molar extrusion 2nd case low TPA o ‘Low' TPA = 5mm clearance from the palate o Tongue presses on TPA resulting in intrusive force to molars o Swallow 800/day = 500gm intermittent force o Not enough force to intrude, but enough to provide vertical anchorage (i.e. prevent molar extrusion) 3rd case Curve of Spee 1. High angle = Weak muscles = COS levels with posterior eruption. § Tailored COS treatment = Intrude the incisors 2. Low angle = Strong muscles = COS levels with anterior proclination (due to posterior teeth prevented from erupting with strong muscles) § Tailored COS treatment = extrusion of posterior teeth One piece intrusion arch o TAD in upper 1-1 region and in 5-6 region o Sectional 19x25ss archwire in upper 2-2 brackets 1. Powerchain from archwire to anterior TAD Three piece intrusion arch o TAD in upper 1-1 region and in 5-6 region, with ligature wire from TAD to archwire in 5-6 region o Sectional archwire in upper 2-2 brackets with distal hooks, as well as sectional wire 3-6 o Intrusion: o Powerchain from archwire to anterior TAD o Powerchain from distal hooks (distal to U2s) to TAD U5-6 region Retention tip for anterior intrusion o Leave TAD between upper anterior teeth o Lingual button in VFR o Patient wears light elastic 2Oz from labial TAD over the incisal edge and VFR to the lingual button References Venugopal, A., Manzano, P. and Rengalakshmi, S., 2020. A Novel Temporary Anchorage Device Aided Sectional Mechanics for Simultaneous Orthodontic Retraction and Intrusion. Case Reports in Dentistry, 2020. Venugopal, A., 2020. Interarch traction for impacted canines. APOS Trends in Orthodontics, 10(1), pp.60-61. Venugopal, A., Manzano, P., Arnold, J., Ludwig, B. and Vaid, N.R., 2020. Treating a severe iatrogenic gingival exposure and lip incompetence–a challenge worthwhile. International orthodontics.
Join me for a summary of the day 1 lectures from this year's virtual IOC. 14 lectures covering: TADs, Facial aesthetics, Biomechanics, Class 2, Early treatment, Expansion, Impacted teeth, Self ligating brackets, Periodonics Speakers: Chris Chang, David Sarver, James Mcnamara, Ravindra Nanda, Junji Sugawara, Noriaki Yoshida, Lorenzo Franchi, Peter Ngan, Sylvain Chamberland, Ewa M. Czochrowska, Yves G. Bolender, Chun-Hsi Chung, Dimitrios kloukos, Mitsuru Motoyoshi Lectures titles: 1. Biomechanics Smart And Visible Biomechanics - Optimizing Treatment Mechanics Based On Prediction Strategy For Long-Term Tooth Movement Noriaki Yoshida 2. Relevancy Of Biomechanics In Clinical Orthodontics In 2020 Ravindra Nanda 3. Class 2 Patient Dependent Factors For The Efficient Treatment Of Class Ii Malocclusion Lorenzo Franchi 4. Early Treatment Of Class Iii Malocclusion With Tads Peter Ngan 5. Expansion In The Early Mixed Dentition Is It Worth The Effort James A 6. Facial Aesthetics Macro To Mini-Explore The Possibilities David M. Sarver, Dmd,Ms Birmingham, Alabama David M. Sarver 7. Facial Aesthetics Vertical Dimension And Facial Aesthetics Sylvain Chamberland 8. Impacted Teeth. Trans Alveolar Transplantation For Impacted Teeth Scientific Evidence And Clinical Practice Ewa M. Czochrowska 9. Is There Any Difference Between Conventional, Passive Self-Ligating And Active Edgewise Self Ligating Brackets A Systematic Review Of The Literature And Network Meta Analysis.Yves G. Bolender 10. Perio Periodontal Considerations In Orthodontic Treatment Chun-Hsi Chung 11. Periodontics And Orthodontics. Long-Term Development Of Gingival Recession In Orthodontically Treated Patients In Comparison To Untreated Individuals. Dimitrios Kloukos 12. Smile Gummy Smile Correction Chris Chang 13. Tads How Has Skeletal Anchorage Changed The Orthodontic Strategies For Class Iii Correction In Adults Junji Sugawara 14. Tads Safety Placement Of Orthodontic Anchoring Screws Mitsuru Motoyoshi
Join me for part 2, where Jae Park describes how to plan either extrusion or intrusion movements, the key evidence around AOB closure and TADs, aligners and orthognathic surgery. Conclusion Resting tongue position is the main soft tissue factor. For increased LAFH, posterior intrusion with tads is indicated. Invisalign for mild AOBs, correction is achieved with incisor extrusion mainly. TADs for intrusion should be placed in the palate should be as distal as possible. If intruding upper molars with TADs, lower molars will erupt unless an appliance is used. 80% of vertical relapse with posterior intrusion occurs in 1st year after debond. How to plan intrusion posterior teeth Vs extrusion of anterior teeth Extrusion: No autorotation Increase incisal show Effects of intrusion: Autorotation of mandible Reduction in LAFH Reduced posterior tooth show CONSIDER EFFECTS ON OCCLUSAL PLANE WITH POSTERIOR INTRUSION If too steep = occlusal interference If too flat = reverse smile How to plan extrusion / intrusion: Upper incisor tip positioned 4mm from the upper lip tip Evidence of AOB closure with TADs Posterior intrusion of 2mm in the upper and 1mm in the lower 1mm, with 3mm of autorotation. Deguchi 2011 TADs and intrusion less stable, 1mm or 30% relapse Sugawara 2002 If intrude upper posterior teeth, use lower fixed or VFR to prevent lower posterior over eruption. Aligners Correct AOBs through 1.5mm incisor extrusion, minimal posterior changes. Khosravi 2017 Orthognathic surgery Reduced stability due to Stylomandibular and medial pterygoid muscles. Solution Strips muscles in surgery
Join me as I summarise Jay Park's lecture looking at the anterior openbites and their management, with a focus on TADs, the good and the bad. Part 1 Soft tissue aetiology and controversy Dental-alveolar correction focus on posterior intrusion Theories of tongue aetiology and AOB · Tongue thrust = persistent visceral swallowing pattern for AOB Subtelny 1965 · Resting anterior tongue posture main factor Proffit 1993 Correct theory relates to resting tongue position: · Anterior resting tongue position remains in between incisors many hours of the day, impedes incisor eruption and maintains AOB R.Juestus 2001 Anterior tongue posture correction · Tongue anterior and high = palatal crib. · Tongue anterior in low = tongue spurs. Indications for dental correction 1/ Posterior intrusion 2/ Intrusion of anterior teeth · Intrusion posterior teeth o Increased LAFH o Excessive posterior gingiva o Mild skeletal discrepancy · Extrusion of anterior teeth o Normal / decreased LAFH o No excess gingival display Posterior intrusion: Bite props as posterior bite plane affect · 2-3mm of composite placed on the palatal cusp. · Molar intrusion achieved = 1.5mm Hernandez 2017 17 months TADS placed in the palate for intrusion Jae Park combines bite plane effect with TADs · RME bonded design acrylic capping on posterior teeth , 2 x TADs dento-alveolar region of the palate, between 5-6. · Powerchain placed over the occlusal surface, from the palatal TAD to the buccal arm on the appliance TADS with modified TPA TPA placed with posterior hook for elastic traction Position of TAD with modified TPA Palatal dento-alveolar region of the 1st and 2ndmolars · Ideal place for upper intrusion: Palatal U6-7, as intrusion vector ideal. · Small interradicular space = challenge to place · As molars intrude, space reduces in between molars Kuroda 2007 Palatal dento-alveolar region of the 2nd premolar / cuspid and 1st molar · Easier location for placement · However tipping of molars mesially occurs due to anterior vector from TAD · Solution: Intrusion bend on 7s Negative effects of palatal TADs and intrusion Palatal cusp intrudes point of application, but buccal cusp doesn't intrude / hangs down maintain occlusal vertical contact Solution to negative effects · Expand with QH and then palatal tad intrusion 2 stage approach, similar to QH, tipping movement then intrusion · Approx. 300g per side for intrusion Anterior extrusion · Tads labially placed distal the upper and lower laterals with pt wearing elastics.
Did You Know: Suicide is the 10th leading cause of death in the US for all ages. (CDC) Every day, approximately 123 Americans die by suicide. (CDC) There is one death by suicide in the US every 12 minutes. (CDC) Depression affects 20-25% of Americans ages 18+ in a given year. (CDC) Suicide takes the lives of over 44,965 Americans every year. (CDC) The highest suicide rates in the US are among Whites, American Indians and Alaska Natives. Only half of all Americans experiencing an episode of major depression receive treatment. (NAMI) 80% -90% of people that seek treatment for depression are treated successfully using therapy and/or medication. (TADS study) An estimated quarter million people each year become suicide survivors (AAS). There is one suicide for every estimated 25 suicide attempts. (CDC) There is one suicide for every estimated 4 suicide attempts in the elderly. (CDC) So Remember: Do A Buddy Check and if needed CALL 1-800-273-8255
Chris Chang describes the use of aligners (Invisalign), and how to resolve common aligner issues and incorporate TADs to achieve predictable outcomes. Aligners work as a pushing appliance: · Pushing surface (active surface) should be at 90 degrees to the direction of tooth movement. · Pulling movements can be achieved through combining with TADs. Reduced aligner predictability: 1. Distalisation 2. Expansion 3. Extraction 4. Incisor intrusion 5. Deep bites The details below describe how to resolve the reduced predictability of aligners. 1. Distalisation · Aligners cannot distalise teeth en-mass, and require sequential distalisation but with incorporating TADs it is possible, for example: o Distalisation in the lower arch: § Buccal shelf TAD in the lower arch (vertically placed, lateral/ buccal to the lower molars). § Intra-arch elastic wear (4.5 ounces) from the lower canine to terminal molar. 2. Expansion · Aligners result in tipping (buccal flaring) with expansion, this can be resolved through attachment placement: o Long horizontal attachment placed buccally with a gingival bevel. § Stage 1 of expansion = Buccal flaring. § Stage 2 of expansion = Attachment aligner interaction results in pushes force palatally, the balancing of moment results in - Buccal root torque = uprights tooth = bodily expansion 3. Premolar / bicuspid extractions & 4. Incisor intrusion · Aligners result in tipping of teeth into the extraction site, this can be resolved through creating a counter moment through attachments o G6 optimised attachments have their pushing surface / active surface positioned to counter the tipping movement and bodily translate the tooth o G6 attachments are located at different heights to generate a force in the direction desired and creating a counter moment. o Kenji formula: change G6 attachments to long vertical attachments · Aligners and extractions can also result in (Fan-fan Dai 2019): o Incisor extrusion and torque loss. o 3mm of posterior anchorage loss and intrusion of molars. Correction · TAD placed in upper incisor region, and elastic wear: o 2 anterior labial TADs – intrude anterior teeth § Elastic from palatal cut out of aligner over occlusal surface to labial TAD. o 2 posterior buccal TADs preserve anchorage § Elastic wear from canines to TAD for retraction 5. Deep bite · Aligners under correct deep bites due to the bite plane affect, this can be resolved with a 3 stage approach 1. Overcorrection of Deep bite in planning. 2. Chewies – on the anterior teeth. 3. Incisor screw – incisor intrusion with elastics. Anterior Crossbite tips 1. Occlusal attachment – to open the bite. References Grünheid, T., Loh, C. and Larson, B.E., 2017. How accurate is Invisalign in nonextraction cases? Are predicted tooth positions achieved?. The Angle Orthodontist, 87(6), pp.809-815. Dai, F.F., Xu, T.M. and Shu, G., 2019. Comparison of achieved and predicted tooth movement of maxillary first molars and central incisors: First premolar extraction treatment with Invisalign. The Angle Orthodontist, 89(5), pp.679-687.
Part 2: Mark describes the clinical factors of space closure and an method of maintaining bone in space opening using miniscrews Space closure aesthetic challenges 1. Gingival height: Canine's height is superior to lateral incisor's 2. Torque: Canine is of buccal root torque, and a lateral is palatal root torque 3. Morphology: Canine is wider and thicker than a lateral incisor. 1. Gingival height solution: a. Bracket placement · Canine bracket placed gingical = extrude gingival margin · Premolar / bicuspid bracket placed incisal = ,intrude gingival margin 2. Torque · Using a lower contralateral 2nd premolar bracket inverted:a achieves 17 degrees of palatal root torque and fits onto the surface of the canine · Mophology · Minimal prep veneer · Narrow buccal lingual via reduction Mechanics – tips for space closure · Always push mechanics · If pull mechanics– distort archform, and alter centreline · TADs can be usedfor anterior anchorage Space closure advantages over space opening · Stable · immediately finish, no 2 stages · Predictable periodontal health · Possible in all malocclusions · Maintains bone · No prosthesis · No evidence of functional problems Space opening miniscrew to maintain bone Does it work? Miniscrews: increase density Al Maaitah AJODO · 3/12 after placement Follow up for 5 years = maintained bone and prosthesis, Ciarlantini 2017 How to insert? o Lateral insertion = as vertical insertion of miniscrew shows infraocclusion o Use of spring to maintain prosthesis References Al Maaitah, E.F., Safi, A.A. and Abdelhafez, R.S., 2012. Alveolar bone density changes around miniscrews: a prospective clinical study. American journal of orthodontics and dentofacial orthopedics, 142(6), pp.758-767. Ciarlantini, R. and Melsen, B., 2017. Semipermanent replacement of missing maxillary lateral incisors by mini-implant retained pontics: A follow-up study. American Journal of Orthodontics and Dentofacial Orthopedics, 151(5), pp.989-994.
Mazyar Moshiri;s lecture from the AAO describes how to modify aligners and clinical pearls. #orthodontics #orthodonticsmasterygroup #farooqahmed #almuzian #glasgoworthodonticacademy #morth #omg @g_orthodontic_a @farooqahmed Modifications to consider to aligner o Change attachment – changes tooth shape o Change aligner shape – e.g. power ridge o Change sequence of tooth movement · Aligner force should be directed perpendicular to the resultant tooth movement required · Vertical control is key o if not can result in heavy anterior contact – curve of spee due to loss of vertical anchorage and a LATERAL OPENBITE o Resolve with anterior intrusion · Deep bite cases should be over treated to AOBs · Clincheck is a force delivery representation, not a virtual treatment objective · AOB cases o Attachments on the occlusal aspect without composite, aids intrusion · Class 3 o TADs in buccal shelf region
Summary of Chris Chan's lecture at the AAO, looking at TADs and their use. #Orthodontics #farooqahmed #morth #omg #glasgoworthodonticacademy #omg @g_orthodontic_a @farooqahmed
This weeks show starts off with music from Hugh Mundell, Jacob Miller, Johnny Clarke, Dennis Brown, Jashwha Moses, Danny Red, Beres Hammond, Gregory Isaacs, Max Romeo, Don Carlos, Third World, Fred Locks, and Horace Andy. New music this week comes from King Jammy with Dennis Brown and Damian Marley, Everton Blender, Taddy P, Alborosie, Luciano, Leba Hibbert, Mr. Vegas, Bob Marley & The Wailers, Protoje, Kabaka Pyramid, Gary Dread, Dre Island, Pad Anthony, Cheshire Cat, Andy Bassford, and Bulby York with Busy Signal and Patrice Roberts. Also this week we ride the Digital Alliance Riddim as well as the Big Rock Riddim featuring artists like Rayven Amani, Earl Cunningham, Carlton Livingston, Hezron, and Teflon. In The Dub Zone you will hear dubs from Nat Birchall, Al Breadwinner and Vn Gordon, Junior Delgado with Sly & Robbie, King Tubby with the Roots Radics, King Jammy, and Jr. Tads with Gregory Morris. Extended dub mixes come from Dubmatix with Tippa Irie, Linval Thompson with Roberto Sanchez, Sugar Minott, Johnny Osbourne, and Steve Boswell with Jah Berry. Enjoy! Hugh Mundell - Jah Fire Will Be Burning - The Crowning Of Prince Jammy - Pressure Sounds Jacob Miller - Zion Gates - Attack Gold Johnny Clarke - Every Knee Shall Bow - Creation Rebel - VP Records Johnny Clarke - Stop Them Jah - Roots Music - Peter Pan Dennis Brown - Oh What A Day - The Promised Land - Blood & Fire Jashwha Moses - Jah Time Has Come w/Dub - No War On Earth - Bristol Archive Records King Tubby & Roots Radics - Orange Hill - More Dangerous Dub - Greensleeves Danny Red - Jah Is Here - Past & Present - Cousins Records Beres Hammond - Call On The Father - Can't Stop A Man: The Ultimate Collection - VP Records Gregory Isaacs - Tan So Back - Hold Tight - Heartbeat Records Gregory Isaacs - Tan So Dub - In Dub - Mafia & Fluxy Max Romeo - Milk & Honey - A Little Time For Jah - Mediacom Don Carlos - Time - Dread Beat & Riddims Vol. 3 - Continental Record Services Third World - Brand New Beggar - Reggae Ambassadors: 20th Anniversary Collection - Mercury Max Romeo - Sipple Out Deh (Jamaican Mix) - Lee Scratch Perry & Friends Presents The Black Ark Years - Trojan Records Fred Locks - Don't Let Babylon Use You - Black Star Liner - VP Records Horace Andy & King Tubby - Better Collie/Better Dub - Jackpot 7” King Jammy & Dennis Brown feat. Damian Marley - Can't Keep - Tracks Of Life - VP Records Everton Blender - Jumbo Jet - Better Day Riddim - Bass Inna Ya Face Taddy P - Better Day - Better Day Riddim - Bass Inna Ya Face Bushman - Music - Conquering Lion - Burning Bushes Music Richie Spice & Chronixx - Unity We Need - In My Brain Riddim - Kickin' Productions Chronixx - Start A Fyah - Game Theory Riddim - Joshua Barlow Capital D - Live Up - Dinner Time Riddim - Wicked Vybz Leba Hibbert - Natty Dread - Taxi Records/High Power Music Alborosie - Table Has Turned - Alborosie Meets The Wailers United: Unbreakable - VP Records Luciano - Too Late - Officer Riddim - BD Labs Mr. Vegas - Moral Decayed Society - Ism - MV Music Freddie McGregor - Stop Losing You - Songs For Reggae Lovers 2 - VP Records Sanchez - Here I Am - One In A Million: The Best Of Sanchez - VP Records Tibio - Never Give In - Far East Riddim - Fat Bird Recordings Dub Troubles - Never Give Dub - Far East Riddim - Fat Bird Recordings Bob Marley & The Wailers - Is This Love (Kaya 40 Mix) - Kaya 40 - Tuff Gong Jah Cure - That Girl - The Cure - VP Records Dub Zone featuring Strictly Dubwize & Extended Dub Mixes Nat Birchall, Al Breadwinner, & Vin Gordon - Ancient Wisdom/Dub Of Wisdom - Sounds Almighty - Tradition Disc Junior Delgado - Bazooka Blast - Raiders Of The Lost Dub - Island Records King Tubby & Roots Radics - Up Town Special - Dangerous Dub - Greensleeves King Jammy - Holy Mount Zion Dub - Waterhouse Dub - VP Records Jr. Tads & Gregory Morris - Play Right - Tad's Records Dubmatix feat. Tippa Irie - Happy - System Shakedown - Echo Beach Dubmatix feat. Tippa Irie - Happy (Aldubb Joy Dub Remix) - Dubmatix Presents: Clash Of The Titans: The System Shakedown Remixes - Dubmatix Linval Thompson - Whom Shall I Fear - Strong Like Sampson 10” Sugar Minott - Walking Through The Ghetto/Walking Dub - Ghetto-ology - Easy Star Records Johnny Osbourne - Fussing & Fighting - Greensleeves Steve Boswell & Jah Berry - Cool Rastaman Cool - Children Of Jah: The Chantells & Friends 1977-1979 - Blood & Fire ============================================== Protoje feat. Chronixx - Flames - A Matter Of Time - Indiggnation Collective/Overstand Entertainment Kabaka Pyramid feat. Pressure Busspipe - Make Way - Kontraband - Bebble Rock/Ghetto Youths International Alborosie - Under Control - Alborosie Meets The Wailers United: Unbreakable - VP Records King Jammy & Dennis Brown feat. Dre Island - Gun Town - Tracks Of Life - VP Records Gary Dread feat. Sensamotion & Signal Fire - Heart Of Gold - Vibrant - Gary Dread Music Rayven Amani - Step Up - Digital Alliance Riddim Vol. 1 - Napem Records Earl Cunningham - Let Dem Talk - Digital Alliance Riddim Vol. 1 - Napem Records Carlton Livingston - Get Off Mi Spot - Digital Alliance Riddim Vol. 1 - Napem Records Devon Clarke - Beat The Banker/Beat The Banker (instrumental) - Call Me Bobo Saw - Bent Backs Records Pad Anthony - Lead The Way - Ram Goat Records Cheshire Cat - Heart & Soul - Ram Goat Records Teflon - Waste Man - Big Rock Riddim - Tad's Records Hezron - One Time Gone - Big Rock Riddim - Tad's Records Desmond Bulby York feat. Busy Signal & Patrice Roberts - Cherry Oh Baby - Master Blaster - VP Records Andy Bassford feat. The Blue People & New Kingston - Johnny Too Bad - The Harder They Strum - Andrew Hobby Bassford Desmond Dekker & The Aces - It Mek - The Harder They Come Soundtrack - Hip O The Maytals - Sweet & Dandy - The Harder They Come Soundtrack - Hip O Jimmy Cliff - The Harder They Come - The Harder They Come Soundtrack - Hip O Horace Andy - Pure Ranking (discomix) - Good Vibes 1975-1979 - Blood & Fire
The episode we have all been waiting for! The Pot Cast meets Adam Dunn! As always a huge thank you to Adam for taking the time to sit down with us and chat all things cannabis, breeding, history and his career! As always this show was made possible by 420 Australia, Organic Gardening Solutions and our awesome Patreon supporters. Feel free to check out the following links https://www.patreon.com/thepotcast http://www.adamdunnshow.com/ https://www.instagram.com/adamdunnshow/ https://www.instagram.com/the_pot_cast/