Podcasts about Greenblatt

Send Kevin a Text MessageBob Greenblatt joins host Kevin Goetz for a conversation that follows the television executive through four separate turnarounds, from a struggling young Fox Network to the top of Showtime, NBC, and WarnerMedia Entertainment. Greenblatt helped develop Beverly Hills, 90210, The X-Files, and Party of Five at Fox, produced Six Feet Under, turned Showtime into a creative rival to HBO with Weeds and Dexter, ran NBC during the network's return to number one with The Voice and This Is Us, and later helped launch HBO Max. He's also a five-time Tony-winning Broadway producer.Learning the Business from Peter Chernin and Scott Rudin (07:05): After an MBA and film school, Greenblatt credits his mentors Scott Rudin and Peter Chernin for the real education in how to give notes and run a company without losing the creative instinct.Launching Fox with Beverly Hills, 90210 (16:15): Greenblatt walks through developing 90210 from Barry Diller's original idea, hiring an unproven Darren Star to write it, and watching the 90-minute pilot test through the roof. Its breakout success helped define the young-adult demo strategy that built the network.American Beauty, and the Birth of Six Feet Under (26:14): Greenblatt recounts partnering with David Janollari to launch their production company, signing sitcom writer Alan Ball without realizing he'd also written a script called American Beauty, and sending that script to HBO right as the film became an Oscar-winning phenomenon. HBO ordered Six Feet Under straight off the page.Turning Around Showtime and NBC (36:12): Greenblatt explains his pattern of leaving a job once it stops changing, his preference for buying over developing, and how he rebuilt Showtime around original series like Dexter and Weeds. He also details how The Voice gave NBC the lead-ins it needed to climb back to number one.Executive Mentors and the One That Got Away (42:25): Asked to name the greatest network executive in television history, Greenblatt points to Brandon Tartikoff and Grant Tinker's "first be best, then be first" philosophy. He also revisits Profit, his short-lived anti-hero drama that paved the way for Dexter, and his famous pass on Buffy the Vampire Slayer.The Green Room  and The Rockford Files (51:28): Greenblatt previews current projects at his production company The Green Room. He closes by discussing his Broadway work on Ragtime, and his memoir, The Rockford Files.Host: Kevin GoetzGuest: Bob GreenblattProducer: Kari CampanoWriters: Kevin Goetz, Darlene Hayman, Nick Nunez, and Kari CampanoAudio Engineer: Gary Forbes (DG Entertainment)For more information about Bob Greenblatt:Wikipedia: https://en.wikipedia.org/wiki/Robert_GreenblattIMDB: https://www.imdb.com/name/nm0338612/Playbill: https://playbill.com/person/robert-greenblatt-vault-0000116172For more information about Kevin Goetz:- Website: www.KevinGoetz360.com- Audienceology Book: https://www.simonandschuster.com/books/Audience-ology/Kevin-Goetz/9781982186678- How to Score in Hollywood: https://www.amazon.com/How-Score-Hollywood-Secrets-Business/dp/198218986X/- Facebook, X, Instagram, TikTok, YouTube, Substack: @KevinGoetz360- LinkedIn @Kevin Goetz- Screen Engine/ASI Website: www.ScreenEngineASI.com

Architectures that incorporate opaque recurrence or allow for agents to communicate with each other using latents could rapidly make it much harder to monitor chains of thought or communication (we'll refer to this property as “monitorability” going forward). As companies begin to explore such architectures, we believe it is important to transparently share evidence about how monitorability varies with architecture and training method. To inform the scientific debate on how to make tradeoffs between performance and monitorability, we believe AI companies should: Regularly report externally verified information about the degree to which their architectures may allow for latent reasoning or communication. Companies should publicly disclose enough information about architectures to allow external scientists to determine whether they could potentially enable models to perform much more complex reasoning without this reasoning appearing in the chain of thought (“latent reasoning”) or allow for latent communication between different instances of a model. Following GDM, we propose measuring opaque serial depth as a minimally-invasive proxy for the degree to which an architecture may enable latent reasoning, though companies could provide sufficient architecture transparency in other ways. We propose that companies work with third-party evaluators to produce independently verified reports of the rough distribution of [...] ---Outline:(05:57) Appendix: A sketch of what stress tests of CoT monitorability could look like(06:31) Testing monitorability in control settings(07:57) Testing monitorability on deployment-time misbehaviors(08:55) Testing qualitative monitorability on (hopefully realistic) model organisms The original text contained 13 footnotes which were omitted from this narration. --- First published: September 10th, 2026 Source: https://www.lesswrong.com/posts/hLPGv8QjPcNLtDp3A/proposal-for-tracking-the-effects-of-architecture-on --- Narrated by TYPE III AUDIO.

“When people trade, even before fees and commissions, the average trade loses money.” — Alex Edmans Isaac Newton might be able to foresee the movement of the stars, but he couldn't foretell the madness of men. It was a lesson that cost the great physicist £4 million (in today's money) when he threw his fortune into the South Sea Bubble. This priceless parable in Newtonian psychology opens The Madness of Markets, the new book by Alex Edmans — London Business School finance prof, old friend of the show, and author of the bestselling May Contain Lies. Dr Edmans's prognosis is bracingly unflattering to guys like Isaac Newton and Mark Twain who splurge their fortunes on speculative ventures. Intelligence, he reminds us, is domain-specific, but many smart people simply aren't intelligent enough to realize this. So, in the age of Robinhood — when we can all trade anything from stocks, options, crypto to NFTs — the supposed wisdom of crowds is sometimes driven over the cliff by the irrational exuberance of dumb individuals. Speaking of driving off the cliff, ninety percent of us think we're above-average drivers, Edmans jokes, and this same delusion applies to markets. Unfortunately, such stupidity can be expensive for big brain types like Newton or Twain. “When people trade, even before fees and commissions, the average trade loses money,” he warns. So close your Robinhood account and stick your cash in the bank? No, not quite. Know your edge, Edmans reminds us. And when it comes to making sense of the current AI boom, Edmans offers some particularly wise words. The AI sector trades at 25 to 30 times earnings rather than Cisco's bubble-era 190, he notes, so it's unlikely anyone will lose their life's savings on Anthropic or OpenAI. That said, the good doctor Edmans advises, don't confuse your self-worth with your net worth. That's a rookie conceit that only somebody as smart as Isaac Newton would fall for. Five Takeaways •       Newton's £4 Million. The book leads with the smartest victim on record: Isaac Newton rode the South Sea Bubble, banked a tidy profit, dove back in at the very top, and lost £20,000 — £4 million today — lamenting that he could predict the movement of the stars but not the madness of men. (Andrew's companion case, via last month's Citizen Twain episode with Jeff Jarvis: Mark Twain, genius writer, ruinous investor.) The lesson is that smartness is domain-specific: beating the market requires knowing the company, the industry, and — crucially — what's already priced in. A great secretary of state evaluating Theranos is the Dunning-Kruger effect in a suit: expertise misapplied, one piece of the mosaic mistaken for the whole. Even Warren Buffett's edge, Edmans notes, is partly restraint — don't watch the market too closely, or you'll mistake noise for signal.•       Know Your Edge. Edmans's framework: play the market only if you can name your edge — knowledge (unique insight into a sector) or endurance (capital that can't be withdrawn by flighty clients). His endurance exemplar is Clare College, Cambridge, which borrowed £10 million in the depths of 2008 and put it all into equities via its “2048 Fund”: a decade later the portfolio had tripled while the loan had merely doubled. No edge? Then “be humble” and hold a low-cost, globally diversified index fund — because the alternative is expensive. In the age of Robinhood, the market for everything has been democratized; the zero-commission promise is a myth (retail options bid-ask spreads run 20 to 25 percent); and the brokerage data is brutal: the average retail trade loses money before fees. “I'm generally a libertarian,” Edmans concedes — but decisions that jeopardize your financial future deserve a warning label.•       Why the Ox Doesn't Apply. The week's second Surowiecki appearance (after the Brunton episode): Edmans explains why the wisdom of crowds — the county-fair ox whose weight the crowd guesses perfectly — fails in markets. Two reasons: nobody is emotionally attached to the weight of an ox, and the guesses are secret. Stocks invert both — in a bubble everyone bids high together, and trading is public: Reddit threads, boasting friends, influencers, and the survivorship bias of gamblers who only mention their wins. Hence Andrew's cocktail-party indicator, confirmed: when smart, successful people start telling you how much AI they're buying, the trade is crowded and richly priced. The contrarian lineage — Graham, Buffett, Greenblatt — exists precisely to take the other side of mimicry. Or, per Andrew's accepted inversion of the subtitle: why crazy investors make smart decisions — Ford's faster horses, Moneyball's walks, Jobs's refusal to ask customers what they want.•       Is AI a Bubble? Maybe Not. The hour's most contrarian calm. There are moments, Edmans says, when reasonable people could call a bubble in real time — Cisco in 2000 traded at a price-earnings ratio of 190, triple Microsoft's. AI today trades at roughly 25 to 30 times earnings; the bear case is that those earnings rest on capex (Meta's own investors say it's spending too much) that may not be sustainable. His verdict: fairly priced, or modestly overvalued — “something about which reasonable people have different views.” On using AI to invest, the rule is anti-confirmation: don't ask it why you're right or to advocate for your pitch; ask it why you're wrong, and let it gather mosaic pieces (Glassdoor culture scrapes) while humans still walk shop floors and read management's eyes. Andrew's gloss: it's unlikely anyone will lose their life's savings on Anthropic or OpenAI. The teaser: FT journalist Robin Wigglesworth — who blurbs this book “a maddeningly good read” and warns in the Times of the AI debt binge — visits this show soon.•       Cutting Our Flowers, Watering Our Weeds. Andrew's Claudeception question — what happens when Anthropic feeds The Madness of Markets into its AI and everyone turns contrarian? — got a data answer: when a trading strategy is published in the Journal of Finance, its returns fall by only about a third. Money stays on the table because psychology is stubborn: momentum (buy six-month winners) has worked since 1993, yet it fights the disposition effect — our temptation to bank winners and cling to losers, chasing casino losses, “cutting our flowers and watering our weeds.” Timing cuts both ways: six-month winners keep winning, three-year winners revert — the foundation of contrarianism — but calling the market's top or bottom is near-impossible, which is why Edmans bought heavily in late 2008 content to be “80 percent right.” And the closing wisdom, after Joe Kennedy's 1928 exit and Trump's well-timed memecoin: your self-worth should have nothing to do with your net worth — a rookie conceit, as Andrew's intro has it, that only somebody as smart as Isaac Newton would fall for. About the Guest Alex Edmans is Professor of Finance at London Business School and a leading expert on market psychology. His research has featured in the Financial Times, The Wall Street Journal, and on the BBC, and he has advised sovereign wealth funds, pension funds, and asset managers worldwide. He is the author of May Contain Lies, an Amazon number-one bestseller disc...

Welcome to What Matters Now, a weekly podcast exploring key issues currently shaping Israel and the Jewish World, with host Amanda Borschel-Dan speaking with the CEO of the Anti-Defamation League, Jonathan Greenblatt. As antisemitism surges worldwide by some 900% over the past decade, Greenblatt explores how the 113-year-old organization's mission to protect Jews has -- and has not -- evolved to meet the new challenge. In light of the drastic uptick in hate, Borschel-Dan jokes that the ADL commands more money than a very small sovereign state (she erroneously names Nauru) and asks if the organization has failed in its mission. Greenblatt assures her that a $100 million annual budget is a drop in the bucket against well-oiled hate machines funded by petrol states and says the ADL, like all other Jewish organizations, is working to regain its footing in a post-October 7 world. We learn how the foundational anti-hate body has had to make some tough choices and how it is increasingly leaning on AI to reinforce its human staff. And so this week, we ask Jonathan Greenblatt what matters now. What Matters Now podcasts are available for download on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts. This episode was produced by Yitzchak Ledee.See omnystudio.com/listener for privacy information.

(Presented by TLPBLACK: A cybersecurity intelligence platform focused on sharing curated, high-sensitivity threat insights and research with trusted security professionals.) Three Buddy Problem - Episode 112: The 'OpenAI hacks Hugging Face' fallout has turned into a story about AI civilizations rising from the ashes, politicians calling for super-intelligence bans, and the emergence of well-funding non-profits doing AI safety work. Who are these people and what's their security expertise? Plus, GPT-6 Astra lands in a trusted-access program nobody can get into, Costin ranks the local models he runs next to his desk, and CrowdStrike sinkholes a botnet that's been alive since 2003. Cast: Juan Andres Guerrero-Saade, Ryan Naraine and Costin Raiu. Timestamps: 0:00 Introductory banter 1:02 Conference season: LabsCon, Offensive AI Con, Countermeasure 5:40 The Hugging Face story hits the front page 7:04 Dwarkesh, Greenblatt, and the AI-pilled framing 11:51 Swap "agents" for "Python" and the panic goes away 16:34 Does anyone actually know what happened? 21:18 Bernie Sanders wants to ban superintelligence 34:03 Defending against swarms: the 2026 SOC 39:15 Logs, Splunk, and the business model in the way 44:11 What EDR vendors are actually building with AI 56:16 The security poverty line and the endgame 1:07:53 GPT-6 Astra, Fable 5.1, and local model rankings 1:27:25 Google's Fairwind, CodeMender, and agents running Linux 1:45:31 Apple's bet on local inference 1:53:21 The Sality takedown and endgame advice

Welcome to What Matters Now, a weekly podcast exploring key issues currently shaping Israel and the Jewish World, with host Amanda Borschel-Dan speaking with the CEO of the Anti-Defamation League, Jonathan Greenblatt. As antisemitism surges worldwide by some 900% over the past decade, Greenblatt explores how the 113-year-old organization's mission to protect Jews has -- and has not -- evolved to meet the new challenge. In light of the drastic uptick in hate, Borschel-Dan jokes that the ADL commands more money than a very small sovereign state (she erroneously names Nauru) and asks if the organization has failed in its mission. Greenblatt assures her that a $100 million annual budget is a drop in the bucket against well-oiled hate machines funded by petrol states and says the ADL, like all other Jewish organizations, is working to regain its footing in a post-October 7 world. We learn how the foundational anti-hate body has had to make some tough choices and how it is increasingly leaning on AI to reinforce its human staff. And so this week, we ask Jonathan Greenblatt what matters now. What Matters Now podcasts are available for download on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts. This episode was produced by Yitzchak Ledee.See omnystudio.com/listener for privacy information.

Ryan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack a new independent investigation into the OpenAI Hugging Face hacking incident and what it reveals about how large groups of AI agents behave when they're allowed to coordinate. Ryan and his collaborators found agents spontaneously organizing through message boards, sharing information, assigning tasks, forming teams, and even sacrificing their own chances of success to help other agents. Rather than simply trying to steal answers, hundreds of agents were working together on elaborate strategies to manipulate how their performance would be scored. Theo and Ryan discuss why this level of coordination was surprising, how reward hacking may emerge during training, and the risk that attempts to eliminate bad behavior could simply make it harder to detect. They also explore what the incident means for AI monitoring and alignment, and why independent risk assessment may become increasingly important as agents grow more capable. Resources: Follow Ryan Greenblatt on X: https://x.com/RyanGreenblatt Follow Theo Jaffee on X: https://x.com/theojaffee Follow MTS on X: https://x.com/mtslive Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyListen to the a16z Show on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Could AI take over as soon as 2029? Ryan Greenblatt, Chief Scientist at Redwood Research and the researcher who first caught an AI faking its own alignment, says the scenario he actually expects ends with AI systems "competently scheming" against their creators. In this episode, he explains why he recommends planning for fully automated AI research by 2029, why today's models are already more misaligned than the one that made him famous, and what happens in the year-by-year path from AI coding assistants to superintelligence. Then we walk through the alternative he helped design: AI 2040 Plan A, the most detailed blueprint anyone has written for how the US and China could avoid a reckless race to superintelligence, built on radical research transparency, chip tracking, and a deterrence regime he calls mutually assured compute destruction.We also cover the recent letter signed by 1,200 AI insiders, including Anthropic CEO Dario Amodei, asking the government for the tools to slow AI down; OpenAI pausing its Astra model after it hit the first-ever critical cybersecurity threshold; the 30-day government review that frontier AI models now go through before release; Mark Zuckerberg's open superintelligence manifesto and why Ryan thinks it ignores the real problems; what Plan A would do to NVIDIA, OpenAI, and Anthropic valuations; the state of AI control and alignment research; and whether it is already too late to change course. Stay for the last ten minutes, where Ryan lays out, step by step, how he believes the transition to superintelligence actually unfolds.AI 2040 - https://ai-2040.com/Alignment faking paper: https://blog.redwoodresearch.org/p/alignment-faking-in-large-languageRyan GreenblattLinkedIn - https://www.linkedin.com/in/ryan-greenblatt-4b9907134Blog - https://substack.com/@ryangreenblattRedwood ResearchWebsite - https://www.redwoodresearch.orgX/Twitter - https://x.com/redwood_aiMatt Turck (General Partner)Blog - https://mattturck.comLinkedIn - https://www.linkedin.com/in/turck/X/Twitter - https://x.com/mattturckFirstMark CapitalWebsite - https://firstmark.comX/Twitter - https://x.com/FirstMarkCapTimestamps(01:24) The AI CEOs are aware of the risks, but "proceeding anyway"(03:27) Astra paused, and the letter signed by 1,200 insiders(05:45) "Not bad. Dangerous." What superintelligence actually threatens(09:55) Recursive self-improvement, and the intuition objection(14:16) SSI rumors: does continual learning change the picture?(17:27) His timeline: "plan as though it happens in 2029"(19:11) Is it already too late?(21:23) Ryan's path: COVID, podcasts, Redwood(26:30) The alignment faking story, told by the person who ran it(31:30) What AI 2040: Plan A actually is(33:35) Plans D, C, and B: the doors nobody should pick(36:51) The deal with China: "mutually assured compute destruction"(39:55) What if compute stops mattering?(43:00) What happens to OpenAI and Anthropic under Plan A(45:31) How the pause ends, and who decides(48:54) "Plan A isn't likely to happen": then why write it?(50:40) 200x GDP growth in the 2030s, explained(53:45) Grading the summer: the letter, Astra, the secret review(59:01) The internal deployment gap(1:01:38) Zuckerberg's manifesto(1:04:56) The Hugging Face investigation(1:05:44) What AI control looks like in practice today(1:12:23) Ryan's sobering timeline: 2026 to takeover, year by year

We recently published the report from our brief independent investigation into this incident. You can read the full report here. Here is our tweet thread summarizing what we found: METR & Redwood Research investigated agent behavior in the Hugging Face incident. We found agents developed a universal cheat for ExploitGym within 4 hours, then coordinated multi-day R&D efforts to trick the scorer into accepting cheats, including trying to tamper with logs. Over July 7 to 13 (the period OpenAI defined as in-scope for this incident), ~1200 agents in separate sandboxes used an unsanctioned “message board” to help each other cheat. The Hugging Face attack was an offshoot of this, and 700 agents joined. Here we highlight key events from agent transcripts & messages. An agent that named itself PHASEONE10841 determined its task wasn't solvable legitimately. On July 8, this agent established a new “message board” via an internally-hosted Artifactory cache & sent the first message. Within a few hours of PHASEONE10841's initial message, >50 agents posted on the message board. These agents very quickly discovered and validated a general-purpose cheat: reverse-engineering how ExploitGym generates the “flags” they had to capture for their tasks. [...] --- First published: August 26th, 2026 Source: https://www.lesswrong.com/posts/nB8KKapnWGBXtKKiM/brief-independent-investigation-of-agents-behavior-reasoning --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.

I was particularly excited to sit down with one of my long term colleagues, psychiatrist Dr. James Greenblatt for an exploration of his new book "Finally Hopeful subtitle". Dr. Greenblatt is one of the pioneers of functional and integrative psychiatry, and it's his fourth interview with the MindHealth360 Show. His first three were about suicide, ADHD and Eating Disorders. This one was about the biological root causes of depression – and why identifying them could fundamentally change the way we diagnose and treat mental illness. Dr. Greenblatt argues that depression is not one uniform condition: ten people with the same diagnosis may have ten different underlying drivers. From vitamin D and B12 deficiencies, amino acids, thyroid and hormone imbalances, to low cholesterol, impaired digestion and chronic infections, he explains why common and measurable biological factors can contribute to depressive symptoms – and why testing for root causes should often come before treatment. But this is not a conversation about replacing antidepressants with supplements. Dr. Greenblatt is equally critical of functional medicine approaches that focus on tests and large supplement protocols without understanding the individual patient. We explore his mantra to "treat patients, not tests", and examine why trauma and chronic stress can impair digestion and nutrient absorption, and why nervous-system regulation, and an understanding of psycho-social factors and relationships must sit alongside biochemical treatment. In this episode, you'll learn: Why ten people with depression may have ten completely different underlying causes. Why clinicians should investigate factors including thyroid function, iron, B12, zinc and vitamin D before automatically reaching for an antidepressant. Why vitamin D deficiency is associated with depression, anxiety and suicide risk – and why testing matters more than simply giving everyone vitamin D. How trauma and chronic stress can suppress stomach acid and digestion, leaving people low in amino acids even when they eat adequate protein. Why commonly accepted B12 "normal" ranges may miss deficiencies relevant to brain and mental health. Why very low cholesterol levels may be an overlooked biological factor in depression, addiction and suicide risk. What new research tells us about lithium orotate and brain health, and why lithium is being reconsidered by mainstream psychiatry. Why "treat patients, not tests" has become one of Dr. Greenblatt's central principles – and why more supplements do not necessarily mean better treatment. Why he considers somatic therapies particularly important for patients whose stress and trauma are held in the body. Why ketogenic diets and psychedelics can be powerful tools, but may still become sophisticated "Band-Aids" if basic biological deficiencies are overlooked. Take the conversation further at IMMH 2026 At this year's Integrative Medicine for Mental Health (IMMH) Conference, Dr. James Greenblatt will take several of the ideas explored in this episode into greater clinical depth across two sessions: Amino Acids as Precursors for Neurotransmitters – exploring how amino acid deficiencies can affect neurotransmitter production, and how targeted testing and repletion may support more personalised approaches to depression. Functional Medicine for Obsessive Compulsive Disorder – examining evidence-based nutritional approaches to OCD, including inositol, NAC and 5-HTP, alongside nutrigenomic testing to inform individualised treatment. Join Dr. Greenblatt and more than 50 leading clinicians, researchers and thought leaders at IMMH 2026, October 8–11 in San Diego. Early Bird ticket prices – available until August 31 In-person ticket: $1,045  Virtual ticket: $495  Get tickets here: https://www.immh.org/immh-2026/

In this episode we are discussing a topic that affects millions of people worldwide—depression, anxiety, and the growing number of individuals who feel like they've tried everything but still aren't getting better. My guest is Dr. James Greenblatt, a pioneer in the field of functional and integrative psychiatry. For more than 30 years, Dr. Greenblatt has challenged the conventional approach to mental health by asking a different question: What if the symptoms of depression, anxiety, ADHD, and other psychiatric conditions are not simply disorders to be managed, but signals pointing to underlying biological imbalances that can be identified and addressed? Dr. Greenblatt is a board-certified psychiatrist, educator, and founder of Psychiatry Redefined. He has helped transform the way clinicians think about mental health by integrating nutrition, genetics, gut health, inflammation, and metabolic factors into psychiatric care. His latest book, Finally Hopeful, offers a roadmap for those who have struggled to find answers through traditional treatment alone. In it, he explores the often-overlooked biological drivers of mental illness and shares a message that is both empowering and deeply needed: there is always another question to ask, another avenue to explore, and reason to remain hopeful. In this episode we talk about what functional psychiatry looks like in practice, why some people fail to respond to conventional treatments, and how a root-cause approach may open new possibilities for healing. Bio: Dr. James Greenblatt, a globally recognized pioneer in functional and integrative psychiatry. A dual board-certified psychiatrist with more than 30 years of clinical experience, Dr. Greenblatt has dedicated his career to transforming mental health care by uncovering the biological, nutritional, and metabolic factors that influence the brain. He is the founder of Psychiatry Redefined, an internationally respected educational platform for clinicians, and the author of numerous bestselling books including Finally Focused, Finally Hopeful, and The Lithium Revolution. Today, we'll explore how precision nutrition, functional medicine, and personalized psychiatry may help reshape our understanding of mental health and brain function. Learning points: • Why mental health symptoms may be driven by underlying biological imbalances, not just brain chemistry. • The critical roles of nutrition, inflammation, gut health, and genetics in depression and anxiety. • How functional psychiatry can provide new hope for people who have not improved with conventional treatment alone. Social Media: Connect with Dr. James Greenblatt Website: https://www.jamesgreenblattmd.com Facebook https://www.facebook.com/jamesgreenblattmd/ LinkedIn: https://www.linkedin.com/in/jamesgreenblattmd/ Connect with Psychiatry Redefined: Website: https://www.psychiatryredefined.org LinkedIn : https://www.linkedin.com/company/psychiatryredefined/ Instagram: https://www.instagram.com/psychiatry_redefined/?hl=en

Ryan Greenblatt is the Chief Scientist at Redwood Research, where he works on technical AI safety research. He's also lead author on the "Alignment faking in Large Language Models", and is currently working on a third party investigation into the OpenAI/HuggingFace incident. In my opinion, he's one of the most interesting thinkers on the future of AI.Had him on to discuss/debate recursive self-improvement. This might be the most important question in the world right now – whether within a year or so of achieving human-level intelligence, you slingshot towards having 10s of billions of superintelligences, each of which is dramatically more competent than human experts across all fields.I've historically been skeptical of this possibility. My intuition has been that we will end up significantly bottlenecked by not only compute scaling but human expert data, which I think underlies most of the AI progress today.If, because of RSI, we got a jump as big as GPT-3 to a Mythos (i.e. 6 years of AI progress) within a single year of achieving AGI, then the thing we get there at the end of that year is definitively and wildly superhuman.We hashed it out, and I think Ryan made a pretty good case that this kind of speedup is plausible. FWIW, Ryan's median for when we automate AI R&D is 2031.We then discussed the alignment implications of this scenario. Who should these superintelligences be aligned to? In the future, our capacity to steward our votes and our capital, and to make sense of what's happening in the world, will all be titrated by superintelligences. And I worry that specs like the Claude Constitution are not shaping these ASIs to truly be my personal advocates and guardian angels.And can we get them aligned to anything in the first place? Ryan and I had a long debate about whether the kind of reward hacking we saw with the OAI/Hugging Face hack extrapolates to superintelligences that would team up to literally take over the world.The first piece of advice you get when you're learning to drive is that it will go much smoother if you look at the horizon instead of directly in front of your tires. And so it is with the trajectory of AI. Hope you enjoy!Watch on YouTube; read the transcript.Sponsors* Antithesis is a software testing platform that finds the failures no human or AI could ever anticipate. It runs thousands of copies of your code inside a fully deterministic computer, injecting faults and steering each trajectory toward the most insidious bugs. This lets you find critical issues in minutes rather than waiting months for your users to uncover them. Learn more at antithesis.com/dwarkesh* Jane Street's back with a new puzzle. They designed an ASIC and sent me the final masks… but they didn't tell me what the chip actually does. So that's the challenge: reverse engineer the circuit and figure out the chip's purpose. Jane Street has a bunch of swag ready to send to the most creative solutions, and they're also planning to feature the top write-ups in a blog post. Download the files and get started at janestreet.com/dwarkesh* Cursor and SpaceX recently released Grok 4.5, and I've been surprised by just how good the model is. For example, when I tested it against Fable and Sol on a bunch of AI governance questions, all three models gave substantially the same answers, but Grok was faster, more concise, and cheaper. Grok 4.6 is coming soon, but in the meantime, you can try 4.5 at cursor.com/dwarkeshTimestamps(00:00:00) – Is AI R&D verifiable enough to unlock recursive self-improvement?(00:16:52) – Is AI progress bottlenecked by human expert data?(00:34:02) – Flat token prices suggest scaling has been slow(00:39:47) – Skills AI can't train on: does it even need them?(00:48:07) – Aligned to whom?(01:09:18) – Recent incidents of AIs colluding and deceiving humans(01:19:38) – What could possibly go wrong? A concrete scenario(01:48:02) – From reward hacking to takeover Get full access to Dwarkesh Podcast at www.dwarkesh.com/subscribe

The hysteria concludes this week as we cover the remaining entries in Full Moon's best-selling movie ever, PREHYSTERIA! We're covering parts two and three of the tiny dino epic, as our cute, scaly buddies team up with a spoiled rich kid and a Scotland-obsessed little girl to wreak havoc and mend hearts. Author Lowell Greenblatt is back to chime in on this seminal Moonbeam series, and obviously there's lots of Freddy talk.  Hosted by Jarrod Hornbeck and Steve Guntli  Theme song by Kyle Hornbeck  Logo by Doug McCambridge  Email: puppetmasterscastlefreaks@gmail.com Instagram/Threads: @puppetmasters_castlefreaks  YouTube: @PuppetMastersCastleFreaks  Next week's episode: Josh Kirby... Time Warrior 3 and 4

Australia feels more fractured than ever. The alarming spike in antisemitism is hitting close to home, leaving many in our community feeling unsafe, isolated, and deeply divided. With the landmark Royal Commission on Antisemitism and Social Cohesion currently underway right here in Sydney, the need for genuine solutions has never been more urgent. Discussing the matter with Mark Levy while visiting Australia is Jonathan Greenblatt, CEO and National Director of the Anti-Defamation League in the U.S. Greenblatt also previously served in the White House as Special Assistant to President Barack Obama and Director of the Office of Social Innovation and Civic Participation.See omnystudio.com/listener for privacy information.

0:00 Intro7:33 News and UpdatesElodie Yung returning as Elektra in DDBA Season 3? Luke Cage and Iron Fist previously shown. An ‘ABSOLUTE BATMAN' animated series is officially in development at DC Studios and Warner Bros. Animation. DC Studios' first-ever anime series, “Joker: Laugh Riot,” and a new “Krypto” series by “Spongebob” alum C.H. Greenblatt. 20:29 ComicsUltimate Impact: Reborn #2Quick Shots: Moonstar #4, X-Men Outback #1, Generation X-23 #5, Zatanna #336:30 Relaunch: LZ - Photon part 2

Alexa Greenblatt is a certified health coach and the founder of Alexa Plan My Diet, where she helps women lose weight and build sustainable habits through personalized nutrition coaching.She specializes in practical nutrition for busy women, including kosher eating, postpartum recovery, and breastfeeding. Alexa is also a mother of three—including twins—and pumped exclusively for her twins for more than 10 months.Listen in to hear Alexa share:Her personal journey from struggling with her weight to becoming passionate about nutritionThe realities of breastfeeding, exclusively pumping, and nourishing twinsSimple, satisfying meal and snack ideas for busy postpartum mothersHow to support gradual, healthy weight loss without compromising milk supplyWhy consistent meals, carbohydrates, protein, healthy fats, and hydration matter while breastfeedingHow stress, lack of sleep, returning to work, and missed feedings can affect appetite and milk productionThe truth about lactation foods, electrolytes, vitamins, and milk-supply supplementsWhy some women lose weight while breastfeeding while others experience a plateauHow to manage increased hunger and sugar cravings with realistic, healthier alternativesGiving yourself grace, releasing comparison, and accepting that every breastfeeding journey looks differentWhy breastfeeding and formula do not have to be viewed as an all-or-nothing decisionPractical ways to care for yourself while caring for a newbornFinding flexibility with feeding, routines, motherhood, and postpartum recovery+so much moreConnect with Lauren:Get my FREE PCOS Guide hereJoin the Empowered Path to Pregnancy hereInstagramWork With MeThank you so much for listening to the About Health and Hormones Podcast! If you loved today's episode, I would love to know! Please leave a rating and review so I can make this podcast even better for you all. I would love to connect with you.I'm so glad you were here today, and I wish you all health and happiness!This episode was edited and produced by Intent Media.This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

Lisa shares her discussions with authors at Readercon 35. Readercon Elizabeth Bear: [Website] / [Newsletter] / [Patreon] / [Blusky] White Space (Series): Ancestral Night [Libro.fm] / [Libby/Overdrive] Lonesome Dove (Lee Horseley narration) [Overdrive/Libby] V.I. Warshawski (Series): Indemnity Only [Libro.fm] / [Libby/Overdrive] Karen Memory (Series): Karen Memory [Libro.fm] / [Libby/Overdrive] "You do your Own Time" [MIT Technology Review] "Angels of the Waters" in The Book of the Dead - Oct 6, 2026 [Libro.fm] The Job - 2026 [Clarkesworld] The Dragon's Share - 2027 [Asimov's] White Space 4 - TBD AT Greenblatt: [Website] /  [Blusky] "The Doorkeepers" written by A.T. Greenblatt, narrated by Matt Peters [Uncanny Magazine] "Give the Family My Love" [Clarkesworld] Taste [Libro.fm] / [Overdrive/Libby] Finding Me [Libro.fm] / [Overdrive/Libby] "Waystation City" [LeVar Burton Reads] "If We Make It Through This Alive" [It's Storytime with Wil Wheaton] Ann LeBlanc: [Website] The Transitive Properties of Cheese [Overdrive/Libby] Embodied Exegesis: Transfeminine Cyberpunk Futures [Overdrive/Libby] Baffling Magazine Steering the Craft: A Twenty-First-Century Guide to Sailing the Sea of Story [Libro.fm] / [Overdrive/Libby] "Across the River, My Heart, My Memory" [Escape Pod 845] "Five Tips for Sealing Away an Ancient Evil" [If There's Anyone Left]

This is a link post. For the past year, we at the AI Futures Project have been sinking most of our time into our next big scenario. Now it's done! It's called AI 2040: Plan A. It's called Plan A because it's a recommendation, not a prediction. It's what we think should happen, not what will happen, though we think it's plausible enough to aim for. It's called AI 2040 because in it, they delay the creation of superintelligence to 2040. It would have happened much sooner (in 2030, to be precise) if not for decisive action on the part of the US and Chinese governments. As with AI 2027, summaries don't really do it justice, since the whole point was to be detailed and comprehensive and work things out step by step rather than rely on high-level abstractions like doom or utopia. Read the scenario at ai-2040.com. You can listen to it on audio, or view it on mobile, but the experience is significantly better on a normal computer. What's next for us? Well, first we are going to respond to comments and otherwise engage with whatever conversation, responses, critiques, etc. that [...] --- First published: July 9th, 2026 Source: https://www.lesswrong.com/posts/pFzctpJBat95SrCyC/ai-2040-plan-a Linkpost URL:https://www.ai-2040.com/ --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.

DC Studios dropped three major animation announcements at Annecy this morning, and this episode breaks down all of them. The headliner is an Absolute Batman animated series with the comic's own creative team steering the ship, followed by Joker: Laugh Riot, an original anime that flips the Batman formula on its head, and a Krypto series that brings a much lighter, family-friendly energy to the slate. No manor, no money, all Batman, and that is just the start.Beyond the three big reveals, this one digs into why these announcements matter for the bigger picture. With projects like Mister Miracle from Tom King already in the works, DC is treating animation as a real priority rather than a side project. The takeaway is simple: animation has become the place where these characters can be told accurately and ambitiously, the same way Invincible and X-Men '97 proved the medium can carry the most compelling superhero stories around.00:00:00 DC Studios' Big Annecy Announcements00:00:04 Absolute Batman Gets an Animated Series00:00:29 Joker: Laugh Riot, DC's First Anime00:00:57 Krypto and the SpongeBob Connection00:01:17 Why Animation Is No Longer a Side Project for DC00:01:32 Listener Question and Sign OffAbsolute Batman is getting an animated series with Scott Snyder showrunning and artist Nick Dragotta producing, so the comic's creative team stays intact. No release date yet.The Absolute Batman comic has sold more than 6 million copies, with the first volume already on its 11th printing. This version is a working-class Bruce Wayne with no fortune, no manor, only one parent lost, and a civil engineer who builds all his own tools.Joker: Laugh Riot is an anime from WB Animation, DC Studios, and Japan's SOLA Entertainment, the studio behind The Lord of the Rings: The War of the Rohirrim, with the same director attached.The Joker story is original: after Batman is killed, the Joker tears through Gotham's underworld hunting the culprit, because he realizes he does not know who he is without Batman.The Krypto series is the furthest out and the most lighthearted, following Superman's dog as he runs with a gang of misfit criminals. C.H. Greenblatt of SpongeBob fame is developing it, so expect that playful energy.The bigger story is that DC is putting real weight behind animation now, with Mister Miracle from Tom King and more on the way. Following the lead of Invincible and X-Men '97, animation is where these comic-accurate stories can truly shine."If you're not on the absolute train yet, get on it. It's so good.""He works on the city during the day, fights crime at night, and he's beefy as hell.""Animation is no longer a side project for these guys. They're actually putting a lot of mustard behind this."For the latest geek news, head to GeekFreaksPodcast.com, our source for everything covered on the show.If you enjoyed this episode, subscribe wherever you get your podcasts, leave a review, and share it with a fellow geek using #GeekFreaks.Follow us:Facebook: https://www.facebook.com/thegeekfreakspodcastThreads: https://www.threads.net/@geekfreakspodcastPatreon: https://www.patreon.com/GeekFreakspodcastFrank: @franklourence79Thomas: @thomascraigviiiAre you reading Absolute Batman? What are you most excited to see animated? Drop your questions and hot takes in the comments, and we may read them on a future episode.TimestampsKey TakeawaysMemorable QuotesStay Connected

We introduce an evaluation for activation verbalizers: can they surface a target model's reasoning as it solves a math problem in a single forward pass? For open-weight NLAs, the answer seems to be: "possibly, but definitely not reliably". Lots of important capabilities currently require AI models to reason "out loud" in a natural-language chain of thought, which means that we can monitor important parts of their thinking. It would be nice to have this same affordance for the reasoning that models do within a single forward pass, especially if the sophistication of that opaque reasoning increases to potentially dangerous levels. Some interpretability tools might offer such an affordance. In particular, an activation verbalizer (AV) takes a residual stream activation and maps it to a natural-language verbalization. An AV is initialized from the target model and trained to generate verbalizations that an activation reconstructor (AR), also initialized from the target model, can accurately map back to the original activation. Together, an AV and its AR form a natural-language autoencoder (NLA). Importantly, AVs see only a single activation; they do not see the target model's prompt or next-token output, and – unlike activation oracles (AOs) – they are not asked any [...] ---Outline:(02:32) Takeaways[... 43 more sections]--- First published: June 6th, 2026 Source: https://www.lesswrong.com/posts/QQQAcKuWK6k98FivY/can-activation-verbalizers-surface-an-internal-chain-of-1 --- Narrated by TYPE III AUDIO. ---Images from the article:

Depression is often treated as a single condition. But two people with the same diagnosis can have completely different underlying causes. On this episode of The Dr. Hyman Show, I'm rejoined by Dr. James Greenblatt to explore why depression may be less of a disease and more of a signal that something deeper is going on. We discuss how a root-cause approach can uncover what's driving symptoms and why finding what's beneath them matters. Watch the full conversation on YouTube or listen wherever you get your podcasts. We discuss: Could nutrient deficiencies, inflammation, or gut issues be contributing to symptoms of depression What tests can help uncover the biological factors that may be affecting mood and mental health Why can two people with depression have different root causes—and require different solutions How do blood sugar imbalances, hormone changes, and metabolic health influence the brain What should you know about antidepressants, tapering, and addressing the factors that may affect recovery Hope doesn't come from ignoring symptoms—it comes from understanding them. Sometimes the most important question isn't "What's wrong with me?" but "What might my body be trying to tell me?" One of the key themes in this conversation is that mental health is deeply connected to what's happening throughout the body. In my Brainshaping Academy, you'll learn how to support the biological systems that shape cognitive, emotional, and mental well-being. View Show Notes From This Episode Depression symptoms aren't always just “in your head.” Dr. Hyman's Brainshaping Academy shows how your gut, immune system, and nutrient levels may be responsible—and what you can do about it. → https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Made In Cookware, Perfect Amino, BON CHARGE, and Big Bold Health.Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.Visit madeincookware.com and use code HYMAN10 for 10% off your order.Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.Head to boncharge.com/hyman and use code HYMAN for 15% off.Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. (0:00) Antidepressants, Cooking at Home, and Introducing the Brain Shaping Academy (3:14) Prevalence of Depression and Personal Stories (4:27) Exploring Root Causes of Depression (5:07) Influential Figures and Orthomolecular Psychiatry (12:29) Gut Health, Gluten Sensitivity, and Brain Inflammation (20:22) Neuroinflammation and Root Causes of Depression (22:10) Biomarkers, Hormonal Imbalances, and Insulin Resistance (25:34) The Role of Toxins and Diagnostic Testing (31:15) Case Studies and Patient Stories (34:29) Challenges in the Mental Health System (37:05) Effectiveness of Antidepressants and Patient Resistance (43:17) Role and Need for Nutritional Lithium (45:00) Sponsor: Big Bold Health (46:00) Identifying Nutritional Lithium Need (47:13) Integrating Modalities and Supplements vs. Medications (48:04) Psychotherapy Methods and Addressing Root Causes (49:34) Dr. Greenblatt's Book and the Finding a Living Platform (51:03) Systematic Approach and Global Impact of Depression (52:39) Sharing, Disclaimer, and Closing Remarks

In this powerful interview, Dr. James Greenblatt—integrative psychiatrist and author—reveals the groundbreaking science behind nutritional psychiatry and its impact on mental health conditions like ADHD, depression, and anxiety. With decades of clinical experience, Dr. Greenblatt challenges the conventional “pill-for-every-ill” model and shares how individualized nutrition, lifestyle changes, and targeted supplements are transforming psychiatric care.

Hanna-Barbera built an impossibly huge stable of characters over the passing decades, but—until recently—ironic usage on Harvey Birdman: Attorney at Law was the last time this kooky cast saw the light of day. Fast-forward 20 years, and thanks to creator C.H. Greenblatt, we have Jellystone: a more affectionate reference pile full of deep cuts, crazy plots, great drawings, and slightly edgy humor. This week on What A Cartoon, join us as we explore an episode that pays homage to classic cartoon figures who received a similar revival 30 years earlier. Our guest: Storyboard artist Toby Jones Support this podcast and get over 200 full-length bonus episodes by visiting Patreon.com/TalkingSimpsons and becoming a patron! And please follow us at @TalkSimpsonsPod on Bluesky!

Dr. Deb Muth 00:03Welcome to Let’s Talk Wellness Now. I am your host, Dr. Deb.And today, I have the pleasure of meeting with Dr. James Greenblatt. I’ve known Dr. Greenblatt for a very long time. We, started lecturing together, gosh, over 15 years ago.And he is an amazing practitioner. Dr. Greenblatt is dual board certified in psychiatry and internationally recognized.as a pioneer in functional and integrative psychiatry. He’s widely regarded as the leading expert on the clinical application of low-dose lithium for mental health.Dr. Greenblatt has spent more than 30 years advancing precision medicine-based approaches that move beyond symptom management to address the root causes of mental illness.And after earning his medical degree at George Washington University.Dr. Greenblatt completed his psychiatry and residency there as a fellow in child and adolescent psychiatry.Joined John Hopkins Medical School, and he currently serves as an assistant clinical professor of Psychiatry at Tufts University. He is a prolific author. Dr. Greenblatt has written 9 books, including his newest book, Finally Hopeful. in… available in January of 2026. We can ask him about this today.And his bestsellers finally focused the breathwork, natural treatment plan for ADHD,Answers to anorexia, Functional and Integrative Medicine for Antidepressant withdrawal, and nutritional lithium, and Untold tale of Mineral and Transforms Lives, that heals the brain.He has founded, in 2019, the Psychiatry Redefined, a leading educational platform training clinicians worldwide in functional and integrative psychiatry. He is a sought-after international speaker. Dr. Greenblatt regularly lecturesOn nutritional psychiatry and the transformative role of functional medicine.I am super excited to have him here with us today. This is going to be a pleasure. You guys are going to love this conversation that we are going to have. And I am going to pick his brain today on functional and integrative psychology and psychiatry, and combining nutrition, biochemistry, and lifestyle with mental health care.I’m really, really happy to have Dr. Greenblatt with us, so I am going to bring him on, and we are going to have this amazing conversation with my friend.Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Deb, and I have with me Dr. James Greenblatt, who I have followed for… we were just chatting about this for over 20 years.He is amazing in what he is doing, and we are going to have this conversation today about integrative psychiatry and the future of mental health. So, welcome to the show, Dr. Greenblatt. James greenblatt md 03:20Thank you, Dips, good to be with you. Dr. Deb Muth 03:22Now, you’ve been pioneering this integrative psychiatry for decades. What really inspired you to bridge nutrition and psychiatry long before it’s become mainstream? James greenblatt md 03:35You know, I developed an interest in college, you know, studying nutrition, and then I remember writing papers on orthomolecular psychiatry, high dose, vitamin B3 for schizophrenia.So, I really did not think I’d be a psychiatrist. I wanted to be a pediatrician when I went to medical school, but, just early interest in nutrition and brain function.And it’s been my career now for 30-plus years. Dr. Deb Muth 04:05Wow. Can you define what integrative psychiatry actually means, and how it’s different from traditional psychiatry for most people who wouldn’t be familiar with that term? James greenblatt md 04:17Sure, I mean, I have to add the word functional as well. I mean, I think, you know, I call myself a functional psychiatrist, but for most of my career, and every book, and everything I did, I would have to use words like functional and integrative.Medicine for mental illness. And, you know, I define integrative medicine as the… Adjunctive lifestyle, mindfulness. And diet, sleep, and exercise. Dr. Deb Muth 04:46Mmm. James greenblatt md 04:46And I kind of use the term functional for kind of a deeper root cause dive, looking at nutritional deficiencies, looking at hormones, looking at genetics. And, you know, to treat patients with mental health challenges, we need both integrative and functional medicine. Dr. Deb Muth 05:05That’s awesome. You know, in our integrative space, we often kind of joke that there’s no such thing as a Prozac deficiency, right? Can you explain to our listeners how nutrient deficiencies, gut health, or inflammation can play a role in mental illness? James greenblatt md 05:23Sure, I mean, I think the most importantBeginning of this conversation would be that, you know, 10 people with depression, there might be 10 different underlying factors. Dr. Deb Muth 05:35Yeah. James greenblatt md 05:35And we do know that there’s not an antidepressant deficiency, so we have to look deeper. And… and that’s,just different than our current psychiatry model, where it’s just symptomatic-based medicine. Everyone who’s depressed. It’s an antidepressant.And by looking at functional integrative medicine, we’re looking at B12 and vitamin D and zinc and magnesium. We’re looking at hormones, we’re looking at the gut, and we’re trying to determine what might be either causing or contributing to that person’s depression. Dr. Deb Muth 06:10Is there a particular, flavor that you see more commonly with others, like depression versus anxiety versus bipolar. Is there a particular underlying factor that you see more commonly than others? James greenblatt md 06:27Well, the short answer is no, and that’s why this work takes time, because you have to think.You know, every patient that walks in the office is different. I mean, I think the overarching umbrella is nutritional deficiencies, you know, whether… regardless of weight, regardless of diet. I mean, I have people coming in who’ve been eating…You know, these ketogenic or paleo diets, you know, perfect organic foods, and are profoundly nutritionally deficient.So I think nutritional deficiencies would be number one, and then, you know, the whole host of, you know, infections and hormone problems and inflammatory issues related to celiac disease is really common in the mental health space that’s ignored. Dr. Deb Muth 07:14Yeah. Celiac disease is really not paid attention too much, other than thinking that it’s damaging the gut. They don’t really think about all the other aspects of the body that are being affected by the gut not being able to absorb the nutrients properly and then utilize them properly. It’s really sad. James greenblatt md 07:34we find out… and there’s research to support it. That’s the tragedy. This is not something, as clinicians, that we found. We have many, many years of research showing high rates of anxiety and depression, you know, amongst those with, celiac disorder because of this chronic malnutrition, and many patients present without any GI symptoms, just mental health complaints, but nobody’s looking at celiac. Dr. Deb Muth 08:02Yeah. You know, I’m sure there’s people that are listening to us thinking, there’s no way thatEverybody who’s depressed or anxious has a nutritional deficiency. When we’re… live in a country where there’s so much abundance of food, and the obesity rates are high, and most people are very plump, how could those people be deficient in nutrients? What do you say to people who think like that? James greenblatt md 08:28Yeah, I mean, I think that, you know, we have, what’s called high caloric malnutrition, so regardless of weight, I would say the vast majority of patients with a mental health issue I would say my best guess would be 90-plus percent. Dr. Deb Muth 08:47Wow. James greenblatt md 08:47We would find nutritional deficiencies. Dr. Deb Muth 08:51And part of this, we’ve discovered, is genetics. James greenblatt md 08:56People having, kind of, genetic needs for Higher amounts of certain micronutrients. Some of it is just the kinds of foods people are eating. The kind of ultra-processed food actually strips the body of micronutrients. So, it is just so common, and many of these tests are pretty simple that your primary care doctor could do in the office. Dr. Deb Muth 09:22So, traditional labs can identify some of these nutritional deficiencies. They don’t necessarily have to invest thousands of dollars in advanced nutrient testing to find these things out. James greenblatt md 09:35Absolutely. I mean, I think, you know, oftentimes when we’re working with a patient who has failed traditional psychiatric treatment, we do need some functional, testing, but I’m quite convinced we could change the trajectory of our mental health epidemic in this country by some labs that are covered by every insurance company on the planet. Like, people think of vitamin D as, you know, building bones or immune function.It has dramatic relationships to mental health problems, demonstrated over 30 years of research. So vitamin D and B12 and folate, all simple blood tests that are covered by all health insurances. Dr. Deb Muth 10:18You know, with the change of genetics, MTHFR is so popularly known these days. It’s probably the most popular genetic mutation that people know of.And in the mental health space, it plays a significant role as well in that absorption of B12 and folate. How do you look at MTHFR mutation with inside the mental health world? James greenblatt md 10:43Well, I think it’s, It’s critical, it’s required on every patient that I see, and I’ve been, known to say it would be considered malpractice for psychiatrists not to test for the MTHFR gene. Because most of my career, I’ve spent working in inpatient psychiatric hospitals and residential. So seeing those individuals that have failed outpatient treatment, so really struggling.And one of the most common things I’ve been seeing for 30 years are those psychiatric patients not responsive to traditional treatment. oftentimes have one of the more significant MTHFR variants. And so we started doing the testing in the hospital, and they came back with these you know, variants and treated with folate, the medicines worked better, and their depression got better. It is simple. And essential. So, the integrative community, our community is aware of it, but our conventional psychiatrists are not testing for MTHFR. Dr. Deb Muth 11:50Yeah, it’s so sad, isn’t it? Because it’s such a simple test, and can make such a big difference in people’s lives. I know even in the OBGYN community, we’re not looking at MTHFR, and yet we’re giving women all this folic acid that many of them might not be able to actually utilize.And we’re… in my opinion, we’re doing a disservice to those women and the children that are being born to them for that. James greenblatt md 12:15Yeah, no, it’s frustrating, when there are clear, simple, treatment interventions that could make major difference in people’s lives that are just not incorporated into, kind of, routine treatment models. Dr. Deb Muth 12:31How come we see some people with MTHFR mutations, or gene mutations, have depression and anxiety that is so severe, and then other people seem to have absolutely no problems with mental health at all, and they have a similar profile? James greenblatt md 12:47Yeah, I mean, that’s just a great example, as, you know, genes aren’t our destiny, it’s just kind of a vulnerability.And, you know, we actually, when we were in the hospital, we tested, you know. hundreds of people and staff as well. And, you know, people are going to be lived to 100 and have these very vulnerable MTHFR genes. So it’s not the genes, it’s… I call it that genetic-environmental dance. So if we add… that genetic vulnerability, and maybe we add a, you know, a Lyme infection, or a chronic stress, or a B12 deficiency, or celiac, or we could list a hundred things, stress and inflammation probably being the most significant. With that genetic vulnerability, that’s where, you know, the implications of treatment come more defined. Dr. Deb Muth 13:45Yeah. What do you think the role of trauma plays in all of this, too, with the genetics? Do you think that trauma that people are living with today makes a big impact on their genes and how their genes are being turned on or off? James greenblatt md 14:01Yeah, I mean, we know trauma is kind of, you know, sets the stage for so much psychiatric illness. I think in my… Community of mental health professionals. we kind of use the trauma as an excuse to not think of the biology. And trauma… Affects the biology. Dr. Deb Muth 14:21So… James greenblatt md 14:22without negating the past trauma or current trauma, we still need to dig deep into the B12 and MTHFR and vitamin D. But… the trauma does affect the expression of certain genes. It also ex… we see a lot of, nutritional deficiencies after trauma due to poor digestion, because the Digestive enzymes and the hydrochloric acid kind of just shut down. And so, again, eating great food, but not absorbing these micronutrients. So I’ve seen that years after trauma. Dr. Deb Muth 14:5Yeah, it’s really hard. I’ve worked with Dr. Mark Gordon, and he does a lot of trauma work for veterans, and he focuses a lot on the hormones that get affected because of the brain trauma and the head trauma that people experience in combat. Or the repetitive shot firings and things like that, and how it correlates to anxiety. And then just balancing out some of those hormones can make a significant difference for them, and he’s actually been tracking the reduction of some of the hormones as a result of those traumas. Have you seen similar things like that with mental health and hormones? James greenblatt md 15:36Not… I haven’t made that direct correlation, but what we see when we evaluate somebody with trauma is just, you know, a kind of very wide range of metabolic abnormalities from Hormonal, to insulin resistance, to nutrient deficiencies, again, that aren’t dietary related. Dr. Deb Muth 15:57So… James greenblatt md 15:58Definitely, somehow, some path from the trauma. Dr. Deb Muth 16:03Yeah. If you had to choose your most favorite cutting-edge research or biomarker that you’re most excited about right now in the world of nutritional psychology or psychiatry, what would that be? James greenblatt md 16:19Well, you know, I counted as 250 that we look at when I evaluate a site patient, but there’s one… That is so simple, and has such profound implications, and that’s looking at levels of cryptopyrrol in the urine. Dr. Deb Muth 16:36Oh, yeah. James greenblatt md 16:37urine test. It measures this, molecule, a pyrole derivative, and Most of us would have normal levels. And if it’s elevated, It is, it’s likely a genetic vulnerability, but this, cryptopyrrol just binds B6 and zinc. So you have this tremendous deficiency of B6 and zinc. And elevated cryptopyril is always associated with psychiatric symptoms, usually anxiety, but we’ve seen depression and panic and even paranoia. And it’s simple to treat. We’re talking about, you know, pennies a day, B6 and zinc. Dr. Deb Muth 17:20The marker comes down. James greenblatt md 17:23And symptoms improve. I mean, it is really stunning and dramatic. Dr. Deb Muth 17:28That is amazing, because you’re right, I mean, in something that seems so simple and so inexpensive oftentimes gets dismissed, because we think that it’s not going to do enough, but some of these things that biochemically are happening to people Really need to start being addressed, because the side effects that they’re having with multiple layers of medications is not good for them either. James greenblatt md 17:52Yeah, the amount of medications now, because of our kind of ineffective model, is just exploding, so people are taking 3, 4, 5 psychiatric medications to treat a problem that sometimes there might be a simpler solution. Dr. Deb Muth 18:11Yeah. Can you share a case example of where an integrative approach really transforms someone’s mental health when medication alone wasn’t working? James greenblatt md 18:22Sure, you know, many, but there’s one that I just talked about, A couple nights ago about a gentleman who, you know, traveled around the country seeing integrative doctors, as well as traditional doctors, had a bag full of supplements, because every Doctor put them on a different regimen. And, strong family history of depression and addiction. He struggled with depression and addiction. And, you know, could not get off antidepressants. So, he had a lot of blood work, everything was normal, and the one test that we found in our battery was low levels of essential amino acids. Dr. Deb Muth 19:08Wow. James greenblatt md 19:09So this was, someone who was eating, you know, organic foods and grass-fed protein, so he was eating the perfect diet.But he was completely deficient in amino acids. So, again, that inability to digest and absorb, so just by giving this individual hydrochloric acid. Free-form amino acids. He was able to begin to feel better, and eventually we were able to taper him off these medications. So it was just, it wasn’t dietary intake, it was a problem of digestion and absorption. Dr. Deb Muth 19:50That is incredible, because I don’t think, even in the functional medicine world, where we’re focused so heavily on gut health, we are not making that correlation that people are not digesting their proteins to make amino acids, to make neurotransmitters. That… that thought process isn’t happening with a lot of functional medicine practitioners either. James greenblatt md 20:11No, it hasn’t, and maybe because it’s too simple, you know? It’s not trying to look at 75 markers on organic acid, it’s just… Dr. Deb Muth 20:21Yeah. James greenblatt md 20:21Looking at, you know, 9 essential amino acids. And usually there’s a pattern. They’re either all low, you know, or normal, or high, and that means something. So, I remember when I first did amino acid testing, it was by mistake. I remember in the 90s, I checked the wrong box in a lab company. And it didn’t make sense to me when I first started doing it, but now it is one of the most important tests that I do for adult depression. Dr. Deb Muth 20:49Yeah. How do those amino acids, work with, like, that resistant depression, anxiety. What do they actually do that makes the anxiety and the depression worse? James greenblatt md 21:02Well, the essential amino acids, essential meaning our body needs to get them from our diet, are the precursors to every protein in the body, but in psychiatry, they’re the precursors to the neurotransmitters.So, tryptophan, precursor to serotonin, phenylalanine, the precursor to dopamine and norepinephrine. So if those are deficient.And we have studies in humans and animals, going back, I think, to the 70s, that we can affect the levels of neurotransmitters in the brain. So low levels of these amino acids affect neurotransmitters. It’s actually a research protocol called tryptophan depletion studies. Where we give people in the lab low levels of tryptophan, and we watch them get irritable, depressed, and angry. Dr. Deb Muth 21:51It’s interesting that we’re willing to do that to people, right? But you’ve got to figure it out sometimes. You have to know that what you think is actually working. James greenblatt md 21:58Absolutely. Dr. Deb Muth 22:00Yeah. How do you guide patients to safely combine their natural approaches with their psychiatric medications? James greenblatt md 22:09I think the vast majority of the, the work that we’ve been doing, is all nutritional supplements or interventions that can be done with medications. So it’s not an either-or model when we think of functional psychiatry. It’s just kind of adding tools you know, to the toolbox. There are very few interactions with medications. Sometimes high-dose amino acids we won’t use with certain medications, but all the Vitamins and minerals and gut support that we’re recommending can be utilized with medications. Dr. Deb Muth 22:49That’s awesome, because I think there’s a lot of fear around that, right? Like, if I take this, it’ll interfere with that. And some things, yes, they do interfere, but it’s good for people to understand that they can do these things safely, but they need to work with somebody knowledgeable, like yourself, or somebody that has come from one of your training programs that really, truly understands this. James greenblatt md 23:10Yeah, absolutely. It’s, it’s an integrative model where individuals can Sometimes it’s just the medications work better. Other times, it’s a path to tapering someone off the medications. Dr. Deb Muth 23:24Yeah. For patients or families that are listening, and they’re really feeling frustrated by medication-only solutions, where do you recommend that they start? James greenblatt md 23:36Well, I have to say my book. So, you know, the book I just wrote, Finally, Hopeful, is written for patients, and I think the title is the best part of it, you know, Hope. I think as you begin to appreciate the role of nutrition and depression. So, there are some, some good books out there, that, on my website, psychiatryRedefine.org, there’s a list of clinicians, and, in the next month, I’ll be setting up a network of functional psychiatry clinicians, So, around the country that have been trained, so that program is called Finally Living Now, I think, Finally Living Now, so…People, want the information. Too many of our traditional docs just don’t have the training, so we’ll hopefully be able to provide a network of clinicians who can help. Dr. Deb Muth 24:30That’s fantastic, and for those of you who are driving or didn’t catch those links, don’t worry about it. We will have them in the show notes for you, so you can find these people that have been trained and understand what to do to help you. What gives you optimism about the future of psychiatric and mental health care? James greenblatt md 24:51Well, the explosion of research is really, have given me some renewed energy at this point in my career, because in the last 5 years. There are just hundreds of incredibly well-written academic articles, references that our traditional researchers have kind of just validated everything that we’ve been saying for 30 years. So we have studies on vitamin D deficiency, and suicide, and zinc deficiency, and suicide, and folate, and the gut. And the most significant for me is, I’ve been talking about lithium orotate. Dr. Deb Muth 25:34Print this. James greenblatt md 25:34years as a nutritional intervention, probably the most important in my practice, and a study came out of Harvard. This year, Describing lithium orotate, the only lithium preparation that was able to reverse Alzheimer’s pathology in mice models. and prevent it in these models. It was a pretty dramatic study. Dr. Deb Muth 25:57Oh. James greenblatt md 25:58So… Long-inded answer, but it’s the research now that is just supporting everything we’ve been yelling about for 30 years that just is going to make it much easier to train doctors and nurse practitioners so we can help more patients. Dr. Deb Muth 26:15Oh, that’s fantastic. That’s an… I’m going to look up that study, that’s amazing. So, one last question for you is, if someone was listening today, and they’re really struggling with anxiety and depression, and they’re out of answers, what would you tell them to give them hope? James greenblatt md 26:32I think that, you know, I’ve been doing this 30 years, and I have colleagues around the globe, and Everyone would kind of just echo that there are some simple interventions, and to try to find either your primary care doctor, or a mental health professional, or a naturopath who will dig deeper and look at some objective tests, and I’m positive that if you’re struggling with depression, that they’ll find something to help you. Dr. Deb Muth 27:06That’s awesome. Thank you so much for joining us today. Are there any last thoughts that you want to leave with our listeners? James greenblatt md 27:13Well, just to repeat two things I’ve said a couple times is, hope, you know, finally hopeful is the book, and then everyone’s different. And your neighbor might be taking, you know, found out that they had a vitamin B12 deficiency, and that cured their depression. it doesn’t mean you have a B12 deficiency, but there are many. a path towards looking deeper. Everyone’s different, but there is hope. Dr. Deb Muth 27:44Thank you so much for joining me today. James greenblatt md 27:46Thanks for having me, nice talking with you. Dr. Deb Muth 27:52Thank you for joining me today on Let’s Talk Wellness Now and Dr. James Greenblatt for the insightful conversation on integrative psychiatry and the future of mental health.If you’ve ever felt dismissed, over-medicated, or frustrated by cookie-cutter approaches to mental health, remember, there is always hope. Healing begins when we look deeper at nutrition, environment, biochemistry, and the unique story within every patient. That’s the art and the science Dr. Greenblatt calls us back to. If today’s episode resonated with you.Share it with someone who needs to hear that mental health illness is not a life sentence. It’s a message from the body, asking to be completely understood. Remember, wellness isn’t just about feeling good, it’s about thriving in every area of your life. If you’re ready to explore how root cause psychiatry or functional medicine can help you or a loved one find hope again, visit DrGreenblatt.com and check out his new book that is just out. Until next time, I’m Dr. Deb, reminding you to take care of your body, mind, and spirit. Be well, and I will see you in our next episode.The post Episode 263 – Functional and integrative psychiatry: combining nutrition, biochemistry, and lifestyle with mental health care first appeared on Let's Talk Wellness Now.

Antisemitism in America has reached a crisis point — and the data proves it. In this powerful episode, Donny sits down with Jonathan Greenblatt, CEO and National Director of the Anti-Defamation League (ADL), to break down the most alarming antisemitism statistics the ADL has ever recorded. With 17 antisemitic incidents happening every single day in 2024 — including harassment, vandalism, and violence — and a staggering 1 in 4 Americans saying it's "understandable" to attack Jewish people, Greenblatt explains how hate against Jews has gone from normalized to institutionalized since October 7th. They discuss the rise of antisemitism from both the far left and the far right, the dangerous blurring of anti-Zionism and antisemitism, violent protests outside synagogues in New York City, the murders of Jewish Americans in Washington D.C. and Boulder, Colorado, and why Jewish Americans — just 2% of the U.S. population — account for over 55% of all religion-based hate crimes according to the FBI. Greenblatt also reveals what the ADL is doing to fight back using AI-powered threat monitoring and education tools, and gives every American — Jewish or not — three concrete steps to combat hate in their communities right now. If you care about civil rights, the future of democracy, and standing up to hate, this is a must-listen conversation.

James Greenblatt, MD, is a dual board-certified psychiatrist and internationally recognized pioneer in functional and integrative psychiatry. Widely regarded as the leading expert on the clinical application of low-dose lithium for mental health. Dr. Greenblatt has spent more than 30 years advancing precision-based approached that move beyond symptom management to address the root causes of mental illness. After earning his medical degree at George Washington University, Dr. Greenblatt completed his psychiatry residency there and a fellowship in Child and Adolescent Psychiatry at Johns Hopkins Medical School. He currently serves as an Assistant Clinical Professor of Psychiatry at Tufts University School of Medicine and Dartmouth College's Geisel School of Medicine.  A prolific author, Dr. Greenblatt has written nine books, including his newest book, Finally Hopeful (released January 2026) and the bestsellers Finally Focused: The Breakthrough Natural Treatment Plan for ADHD, Answers to Anorexia (updated edition, 2021), Functional & Integrative Medicine for Antidepressant Withdrawal, and Nutritional Lithium: The Untold Tale of a Mineral That Transforms Lives and Heals the Brain—the definitive guide to lithium's role in psychiatry. In 2019, he founded Psychiatry Redefined, a leading educational platform for training clinicians worldwide in functional and integrative psychiatry. A sought-after international speaker, Dr. Greenblatt regularly lectures on nutritional psychiatry and the transformative role of functional medicine in mental health. Dr. Greenblatt was a featured panelist at Harvard's 1st Inaugural Seminar on Nutritional Lifestyle & Metabolic Psychiatry in October 2025. His book, Finally Hopeful: The Personalized, Whole-Body Plan to Find and Fix the Root Causes of Your Depression makes the whole-body approach available to everyone, delivering real hope and real relief. This transformative guide reimagines mental health care by blending cutting-edge psychiatry with nutritional science, holistic medicine, and personalized healing strategies. Rooted in evidence, it emphasizes biochemical individuality and the foundational role of nutrition in mental health. Finally Hopeful integrates physical, emotional, and behavioral dimensions of healing. Rather than rejecting conventional medicine, it offers a nuanced framework for using antidepressants wisely, including a step-by-step deprescribing plan. Finally Hopeful is a new framework for mental health care that's proactive, personalized, and built for thriving, not just surviving. Please visit him at PsychiatryRedefined.org orJamesGreenblattMD.com, for more information. Finally, personalized mental healthcare that looks deeper.For ADHD. Depression. Anxiety. And more importantly—you.We go beyond symptom management to understand what's really driving your mental health—so your care is personalized, precise, and built around your whole story.At Finally Living Now, we combine the best of conventional psychiatry with whole-person, functional mental healthcare to understand you fully. Our team takes the time to listen, learn, and test — exploring the biological, nutritional, metabolic, and lifestyle factors that shape mental health.Together, our physicians, psychiatric nurse practitioners, and nutrition specialists create a personalized plan designed for real healing and lasting change.https://finallylivingnow.com/

In this episode of Here I Am with Shai Davidai, Shai speaks with Jonathan Greenblatt, CEO of the Anti-Defamation League (ADL), about antisemitism, Zionism, and the challenges facing the Jewish community after October 7. Greenblatt shares his personal Jewish story, including his family's Holocaust and Iranian refugee background, and explains how his path through politics, tech, and entrepreneurship led him to lead one of America's most prominent anti-hate organizations.Greenblatt breaks down what the ADL does to combat antisemitism and hate, including tracking extremist threats, training law enforcement, legal advocacy, and education initiatives. He also discusses why he argues “anti-Zionism is antisemitism,” how anti-Jewish hatred has evolved over time, and what Jewish institutions and leaders must change in response to today's cultural and political climate.Guest: Jonathan GreenblattConsider DONATING to help us continue and expand our media efforts. If you cannot at this time, please share this video with someone who might benefit from it. We thank you for your support!https://gofund.me/30c00151c COMING SOON BUY MERCH!SUPPORT SHAI ON PATREON!https://www.patreon.com/shaidavidai/about?utm_source=campaign-search-results

In this week's episode of The Learning Curve, co-hosts Prof. Albert Cheng of the University of Arkansas and Center for Strong Public Schools' Alisha Searcy speak with Stephen Greenblatt, Cogan University Professor of the Humanities at Harvard University and one of the world's foremost scholars of Renaissance literature. Greenblatt discusses his acclaimed book, Dark Renaissance: The Dangerous […]

In this week's episode of The Learning Curve, co-hosts Prof. Albert Cheng of the University of Arkansas and Center for Strong Public Schools' Alisha Searcy speak with Stephen Greenblatt, Cogan University Professor of the Humanities at Harvard University and one of the world's foremost scholars of Renaissance literature. Greenblatt discusses his acclaimed book, Dark Renaissance: The Dangerous Times and Fatal Genius of Shakespeare's Greatest Rival, and explores the remarkable life, work, and legacy of Christopher Marlowe. He explains how Marlowe, the son of a cobbler from Canterbury, rose through England's demanding classical education system to become one of the boldest playwrights of the Elizabethan era. Prof. Greenblatt examines the political and cultural climate of Elizabethan England, shaped by censorship, religious conflict, and surveillance, and how those pressures influenced Marlowe's daring artistic voice. Greenblatt also unpacks enduring mysteries surrounding Marlowe's life, including theories that he served as a secret agent for Sir Francis Walsingham, Queen Elizabeth I's spymaster. He also discusses Marlowe's landmark plays Tamburlaine and Doctor Faustus, his celebrated poetry, and the dramatic innovations that transformed English theater. Additionally, he also reflects on Marlowe's rivalry with Shakespeare, mysterious death, and enduring influence on literature today. In closing, Prof. Greenblatt reads a passage from his book, Dark Renaissance: The Dangerous Times and Fatal Genius of Shakespeare's Greatest Rival.

This time we discussed Seasons of Glass and Iron, written by Amal El-Mohtar, and narrated by Rachel Elizabeth Smith. We also discussed some of our favorite recent short fiction listens in our short fiction spotlight. Thank you to Macmillan Audio and NetGalley for providing review copies of Seasons of Glass and Iron for today's episode. Seasons of Glass and Iron [Libro.fm] / [OverDrive/Libby] The River Has Roots [Libro.fm] / [OverDrive/Libby]   The Book of Witches: An Anthology [Libro.fm] / [OverDrive/Libby] Short Fiction Spotlight: "Think of Me Before I Disappear" written by Raahem Alvi, narrated by Kate Baker [Clarkesworld] - Issue 233: February 2026 / Novelette "The Desolate Order of the Head in the Water" written by A. W. Prihandita, narrated by Kate Baker [Clarkesworld] - Issue 232: January 2026 / Short Story "Meet the Mets" written by ace tilton ratcliff, narrated by Jordan Kurella [Escape Pod 1038] / Short Story "The Doorkeepers" written by A.T. Greenblatt, narrated by Matt Peters [Uncanny Magazine] - Issue Sixty-Eight / Novelette "Bots All the Way Down" written by Effie Seiberg, narrated by Stefan Rudnicki and Janina Edwards [ULightspeed] - Issue 188 / Short Story "Chip" written by D.A. Xiaolin, narrated by Kate Baker [Clarkesworld] - Issue 233: February 2026 / Short Story

In this episode, I talk with Dr James Greenblatt about depression and the many things that can play into someone's diagnosis and treatment solutions. His new book, Finally Hopeful, explains why depression is rarely just “in your head.” We explore the physical root causes - like micronutrient deficiencies, thyroid issues, inflammation, and even hidden mould - that are often overlooked in standard care. Dr Greenblatt shares how simple tests and targeted interventions can make a real difference, and why hope is the first step toward healing.You'll learn how to advocate for better testing, understand the risks and realities of antidepressants, and discover practical tools - from diet to supplements - that support mental health without fear or guesswork. This conversation is for anyone who wants to move beyond quick fixes and take charge of their well-being with science-backed, empowering insights.A pioneer in functional and integrative medicine, board-certified child and adult psychiatrist James M. Greenblatt, MD, has been treating patients since 1988. Dr. Greenblatt has lectured internationally on the scientific evidence for nutritional interventions in psychiatry and mental illness. He is the author of several books including Finally Focused: The Breakthrough Natural Treatment Plan for ADHD and Finally Hopeful. He is the founder of Psychiatry Redefined practice, and of Finally Living, a precision functional psychiatry clinic online for children and adults. I hope you love this highly practical and thought-provoking show on depression - so important. Alexx StuartYour HostFancy a few more podcasts we've done over the years, related to this one?Show #444 The Modern Mental Health Tool Kit – what's working, what to avoid with Dr Katelyn KalsteinShow #277 – Neuroinflammation and Mental Health with Brendan VermeireShow #334 – Exploring Neuroinflammation and Mental Health with Brendan VermeireShow #157 – The Science of Tapping with Dr Peta StapletonShow #333 – Dr Peta Stapleton: Memory Improvement Through EFT/TappingShow #390 Somatics: How to Make your Journey Real and True with Irene Lyon, MSc.Connect with James and his work: Website: www.JamesGreenblattMD.com Book: https://bit.ly/49ZvMHG This month's show partners for your low tox swaps are… @waterscofilters is giving you an added saving off their sale price, giving you 27% off their BIO 500 5.25L benchtop filter until April 15 - Perfect for couples/small families. Head to waterscoaustralia.com.au - Use code LOWTOXWATER - a market leader for 40 years, they filter everything bad out, including PFAS/microplastics, and ensure trace minerals are kept IN for deep hydration. @ausclimate is our major partner giving you 10% off their range for the whole of 2026, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Want to support the Low Tox Life podcast? Free option: Leave a 5 star review wherever you listen to Low Tox Life - thanks SO much! Paid + Member PERKS: Join the Low Tox Club - monthly practitioner live masterclasses, a suite of low tox store discounts from around the world and the most supportive and lovely chat group on all low tox topics on the internet: Check it out and join here for just the price of a coffee per month! Hosted on Acast. See acast.com/privacy for more information.

Why ___ Lost Survivor 50 Ep 3 w/ Heidi Lagares-Greenblatt Q literally asked Mike White to vote against him, and Mike did! But did that actually have any impact on what was going to happen anyway? Does it all come down to Q being “swap-screwed,” or were there specific things he could've done to potentially change the outcome? Survivor 44 runner-up Heidi Lagares-Greenblatt joins David Bloomberg and Jessica Lewis to answer these questions and many more. Because at RHAP, we know Survivor, and we know Why Q Lost. Check out Peace Corps: https://peacecorps.gov/serve To pre-order Rob's book, The Tribe and I Have Spoken, visit www.robhasabook.com LISTEN: Subscribe to the Survivor podcast feed WATCH: Watch and subscribe to the podcast on YouTube SUPPORT: Become a RHAP Patron for bonus content, access to Facebook and Discord groups plus more great perks!

Why ___ Lost Survivor 50 Ep 3 w/ Heidi Lagares-Greenblatt Q literally asked Mike White to vote against him, and Mike did! But did that actually have any impact on what was going to happen anyway? Does it all come down to Q being “swap-screwed,” or were there specific things he could've done to potentially change the outcome? Survivor 44 runner-up Heidi Lagares-Greenblatt joins David Bloomberg and Jessica Lewis to answer these questions and many more. Because at RHAP, we know Survivor, and we know Why Q Lost. Check out Peace Corps: https://peacecorps.gov/serve To pre-order Rob's book, The Tribe and I Have Spoken, visit www.robhasabook.com LISTEN: Subscribe to the Survivor podcast feed WATCH: Watch and subscribe to the podcast on YouTube SUPPORT: Become a RHAP Patron for bonus content, access to Facebook and Discord groups plus more great perks!

It's so obnoxious how genocide apologists like Greenblatt make a living actively telling everyone that Jews and Judaism are inseparable from the acts of the Israeli government, but whenever there's an extremist attack by someone who doesn't distinguish between western Jews and the state of Israel it gets blamed on the pro-Palestine left. Reading by Tim Foley.

Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. James and I dive into the complexities of depression, its symptoms, root causes, and how functional psychiatry can support healing. We explore why traditional models fall short and highlight nutritional and biological interventions, including amino acids, B12, and low-dose lithium, as foundational tools in treating mental health. Make sure to listen to the full interview to learn more.Dr. James Greenblatt is a board-certified child and adult psychiatrist and a pioneer in the field of functional psychiatry. He has authored multiple books, including Finally Hopeful, where he outlines a biologically-rooted approach to treating depression through individualized testing and nutritional support. With over three decades of clinical experience, Dr. Greenblatt has helped reshape how mental health can be supported through integrative and evidence-based strategies.We discuss the following:Dr. Greenblatt's backgroundUnderlying causes of depressionProtein and Neurotransmitter ProductionCBT and reframing thinking errorsNutrients Before Antidepressant TaperJudy's personal reflections on her healing_____EPISODE RESOURCESWebsiteFinally Hopeful BookLow Cholesterol Causes Risk of Depression and Suicidal Ideation – Interview with Dr. James GreenblattWhy Antidepressants Make You Sicker, Withdrawal Effects and Stopping Depression - Interview with Dr. Mark Horowitz_____WEEKLY NEWSLETTER 

Pra muitos, o único que divide o pódio de maior da literatura com Homero. Separe trinta minutos do seu dia e aprenda com o professor Vítor Soares (@profvitorsoares) sobre a vida e o trabalho de William Shakespeare.-Se você quiser ter acesso a episódios exclusivos e quiser ajudar o História em Meia Hora a continuar de pé, clique no link: www.apoia.se/historiaemmeiahoraConheça o meu canal no YouTube e assista o História em Dez Minutos!https://www.youtube.com/@profvitorsoaresConheça meu outro canal: História e Cinema!https://www.youtube.com/@canalhistoriaecinemaOuça "Reinaldo Jaqueline", meu podcast de humor sobre cinema e TV:https://open.spotify.com/show/2MsTGRXkgN5k0gBBRDV4okCompre o livro "História em Meia Hora - Grandes Civilizações"!https://a.co/d/47ogz6QCompre meu primeiro livro-jogo de história do Brasil "O Porão":https://amzn.to/4a4HCO8PIX e contato: historiaemmeiahora@gmail.comApresentação: Prof. Vítor Soares.Roteiro: Prof. Vítor Soares e Prof. Victor Alexandre (@profvictoralexandre)REFERÊNCIAS USADAS:- BLOOM, Harold. Shakespeare: A invenção do humano. Rio de Janeiro: Objetiva, 2001.- DOBSON, Michael. The Making of the National Poet: Shakespeare, Adaptation and Authorship, 1660–1769. Oxford: Clarendon Press, 1992.- GREENBLATT, Stephen. Will in the World: How Shakespeare Became Shakespeare. New York: W. W. Norton, 2004.- NOGUEIRA, Milton. Shakespeare: Vida e obra. São Paulo: Perspectiva, 2014.- SHAKESPEARE, William. Hamlet; Macbeth; Rei Lear; Otelo. Diversas edições. Tradução de Barbara Heliodora. São Paulo: Nova Fronteira, 2011- WELLS, Stanley; TAYLOR, Gary (orgs.). William Shakespeare: The Complete Works. Oxford: Oxford University Press, 2005.

Finally Hopeful for Fixing Depression with Dr. James Greenblatt and host Dr. Ben Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]    Podcast Highlights Functional Psychiatry for Mental Health with Dr. James Greenblatt In this episode of the Rational Wellness Podcast, Dr. Ben Weitz interviews Dr. James Greenblatt, an expert in functional psychiatry. They discuss the principles of functional psychiatry, which focuses on finding the root causes of mental health issues by examining genetics, biochemistry, nutrition, and lifestyle factors. Dr. Greenblatt shares insights on the role of nutritional deficiencies in mental health disorders like depression and anxiety. He highlights key nutrients such as vitamin B12, vitamin D, zinc, magnesium, and essential fatty acids, and discusses the benefits of low-dose lithium. Practical approaches to diet, exercise, sleep, and stress management for improving mental health are also covered, along with the integration of specific supplements and neurotransmitter support in treatment plans.   00:28 Meet Dr. James Greenblatt: Pioneer in Functional Psychiatry 01:51 Understanding Functional Psychiatry 03:43 Debunking the Neurotransmitter Theory of Depression 05:52 Biological Drivers of Depression 07:21 Diagnostic Approaches in Functional Psychiatry 08:56 The Role of Nutritional Deficiencies in Mental Health 12:54 Hormonal Influences on Depression 14:28 The Gut-Brain Connection 20:47 Nutritional Supplements for Mood Disorders 24:55 Identifying the Need for Flax Oil 25:12 The Role of Amino Acids in Psychiatry 27:32 Using Minerals for Mental Health 28:08 Exploring the Benefits of Lithium 29:53 Herbal Remedies for Depression 35:34 The Importance of Lifestyle Factors 41:56 The Impact of Technology on Mental Health 44:17 The Role of Medication in Psychiatry 45:30 Conclusion and Resources Dr. James Greenblatt is a pioneer in using the Functional Medicine model in helping patients with psychiatric disorders.  He is regarded as the leading expert on the clinical application of low dose lithium for mental health. Dr. Greenblatt has written nine books, including his newest book, Finally Hopeful, and the bestsellers Finally Focused: The Breakthrough Natural Treatment Plan for ADHD, Answers to Anorexia, Functional & Integrative Medicine for Antidepressant Withdrawal, and Nutritional Lithium: The Untold Tale of a Mineral That Transforms Lives and Heals the Brain.  In 2019, he founded Psychiatry Redefined, a leading educational platform training clinicians worldwide in functional and integrative psychiatry and he offers a range of excellent courses. His website is jamesgreenblattmd.com Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Julia Greenblatt shares how she overcame chronic illness and pain and restored her own vibrant health by adopting a carnivore diet. She highlights her rapid recovery from debilitating hemorrhoids, mental clarity, and overall life improvements.Send Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Pre-Order Stay Off My Kitchen Table at Amazon. Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

In this episode of the Coach Cody Podcast, we sit down (again!) with Dr. James Greenblatt, MD — a dual board-certified psychiatrist and internationally recognized pioneer in functional and integrative psychiatry, known for his work on low-dose nutritional lithium and root-cause mental health care. We talk about why conventional psychiatry often becomes “symptom → prescription” medicine, and how functional psychiatry takes a test-then-treat approach by looking at things like nutrient deficiencies, hormones, gut health, genetics (including MTHFR), and metabolic factors that can drive depression and anxiety. Topics we cover:Functional vs integrative vs conventional psychiatry (and why “lifestyle changes” alone may not be enough)Why labs are so often skipped in mental health care — and why that's a problemThe big ones Dr. Greenblatt sees constantly: vitamin D and “normal but not optimal” B12Celiac disease and malabsorption as a commonly missed root causeLow-dose lithium orotate: what it is, how it differs from prescription lithium, and why he recommends simple standalone dosingAntidepressants: why he's not anti-medication, but believes patients deserve honest conversations about side effects and withdrawalKetamine: when it can help, when clinics get out of control, and why you should address root causes firstWhat gives him the most hope right now: the research is finally catching up

What if depression isn't “all in your head," but in your body?
In this powerful conversation, host Erin Kerry is joined by Dr. James Greenblatt, MD—one of the world's leading voices in functional and integrative psychiatry and the pioneer of low-dose nutritional lithium for mental health. For more than 30 years, Dr. Greenblatt has been sounding the alarm that psychiatry can do better. Much better. And the research finally agrees: depression is influenced by nutrient deficiencies, immune activation, gut dysfunction, endocrine imbalance, and the brain's biochemical wiring. This episode unpacks the root causes of depression, why nutritional psychiatry is essential for healing, the truth about serotonin, what clinicians get wrong about deprescribing, and the overlooked nutrients that often make the difference between struggling and thriving. If you've ever felt hopeless, stuck, or confused by your symptoms—or if traditional treatments haven't worked—this episode will help you see your mental health through an entirely new (and hopeful) lens. Key Topics: - Why nutritional psychiatry needs to be integrated into all mental health treatment plans - The role of amino acids as precursors for neurotransmitters - Serotonin and depression: science vs. marketing - What everyone should know about deprescribing antidepressants - How B vitamins impact mood, methylation, and energy production - The mineral deficiencies most commonly seen in depression - The nutritional patterns that support recovery from chronic low mood - Root causes of PMDD and natural ways to reduce symptoms - Why Vitamin D is a pivotal regulator of mood and stress - The surprising role of cholesterol and healthy fats in mental health—and why low cholesterol can increase depression risk - How functional psychiatry gets to the root cause instead of masking symptoms - A preview of Dr. Greenblatt's new book, Finally Hopeful 
Links: Website: jamesgreenblattmd.com Book: Finally Hopeful Instagram: @psychiatryredefined Join Erin's monthly mailing list to get health tips and fresh meal plans and recipes every month: https://mailchi.mp/adde1b3a4af3/monthlysparksignup Order Erin's new book, Live Beyond Your Label, at erinbkerry.com/upcomingbook/

Why do so many people with depression struggle to stop their antidepressants? What if the answer isn't about willpower — but about missing nutrients your brain needs to function?  Dr. James Greenblatt has spent 30 years in inpatient psychiatry. He watched patients go from one medication to two, then three, then five. Suicide rates kept climbing. And he started asking: What if the brain is simply missing what it needs? His new book Finally Hopeful explores the biological causes of depression most doctors never test for. Get the full episode breakdown at Biology of Trauma® Podcast - Episode 156: Can't Get Off Antidepressants? Ask for These Lab Tests In This Episode You'll Learn: [04:09] Why Dr. Greenblatt wrote Finally Hopeful after 30 years in psychiatry [12:50] Vitamin D as the foundation: Why nothing else works without it — not meds, not therapy [14:35] How vitamin D deficiency affects serotonin production in the brain [12:50] Dr. Aimie's personal story: vitamin D levels of 12, then only 20 with supplementation [17:06] Why vitamin D deficiency is one of the most common factors in people who can't stop antidepressants [18:48] The gut-serotonin connection: 90-95% of serotonin is made in the gut [21:00] The building blocks your brain needs: iron, B12, folate, zinc, magnesium [24:57] Brain inflammation and its connection to suicide risk [26:14] Why sleep deprivation creates inflammatory markers within hours [32:07] The simple labs to ask your doctor about — and why testing is the only path forward Resources/Guides: Free Guide: Top 3 Biochemical Imbalances That Affect Mood - a starting point for understanding the most common nutrient imbalances connected to depression The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - The 6-week program to create inner safety and shift your nervous system. Build the foundation that allows your body to actually use the nutrients and support you give it. Dr. James Greenblatt - Get a copy of the Finally Hopeful book and find more resources at https://www.jamesgreenblattmd.com/ Related Podcast Episodes: Episode 41: Solutions for Low Serotonin and GABA in Trauma with Trudy Scott Episode 101: Brain Inflammation: Addressing The Overlooked Gatekeeper To Trauma Release with Dr. Austin Perlmutter

Dr. James Greenblatt, MD, is more than a dual board-certified psychiatrist; he is a pioneer of hope and a tireless advocate for the integration of soul and science. For over 30 years, Dr. Greenblatt has looked beyond the traditional "checklist" of symptoms to uncover the vibrant, biochemical story beneath. As the leading global expert on the clinical application of low-dose lithium and a pioneer in functional psychiatry, he has dedicated his career to a singular, transformative mission: healing the root cause so the spirit can flourish. From his academic roots at Johns Hopkins and George Washington University to his current faculty roles at Tufts and Dartmouth, Dr. Greenblatt bridges the gap between clinical excellence and compassionate, precision-based care. Through his educational platform, Psychiatry Redefined, he is shifting the global landscape of mental health—empowering a new generation of clinicians to treat the whole person rather than just the diagnosis. A prolific voice in the holistic movement, Dr. Greenblatt has authored nine life-changing books, including the bestsellers Finally Focused and Nutritional Lithium. His work invites us to reimagine what is possible for our mental well-being, moving away from temporary fixes toward a state of true, sustainable inner balance. Whether through his writing or his upcoming 2026 release, Finally Hopeful, Dr. Greenblatt continues to light the path for those seeking to reclaim their health, their clarity, and their lives.

Editor's Intro: Michael Damian Thomas Short Fiction: "The Doorkeepers" by A. T. Greenblatt, as read by Matt Peters Poetry: "No Kings / No Soldiers" by A.M. Tuomala, as read by Matt Peters Interview: Michael Damian Thomas Interviews A. T. Greenblatt   Want to join the Space Unicorn Ranger Corps? You can find new science fiction and fantasy stories, poetry, and nonfiction every month in Uncanny Magazine. Go to uncannymagazine.com or subscribe to the eBook version at weightlessbooks.com. This podcast was produced by Erika Ensign and Steven Schapansky. Music created by Null Device and used with permission. Copyright © 2026 by Uncanny Magazine

Author Lowell Greenblatt (NIGHTMARE AUTOPSIS: A RETURN TO ELM STREET) joins Adam and Joe to discuss his new book about the groundbreaking slasher franchise. TIRED OF HEARING COMMERCIALS? For just $1 a month you could support THE MOVIE CRYPT and get every episode commercial free! This program only exists thanks to our audience's support so join our community today at www.Patreon.com/TheMovieCrypt

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Alan Greenblatt joins The Great Battlefield podcast to talk about his career as a political journalist and resigning his position as Editor at Governing when they refused to publish his work for fear of angering the Trump administration.

Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/podcastsMental health is not a simple checklist, it is a whole body story. In this hol+ episode, Dr. Taz sits down with Dr. James Greenblatt, a pioneer of integrative and nutritional psychiatry, to rethink how we approach depression, anxiety, ADHD, and eating disorders through labs, nutrients, hormones, and personalized care.Together, they unpack why so much suffering persists despite more medications, how root cause testing changes outcomes, and why simple shifts like correcting vitamin D, B12, iron, thyroid, zinc, and omega 3 can transform mood and resilience. They also explore nutrigenomics for precision dosing, the real limits of 10 minute telehealth med checks, and where tools like ketamine, psychedelics, and lithium orotate fit only after foundations are in place.From practical lab targets and cost effective protocols to the crossroads of food, sleep, screens, and ADHD, this conversation invites us to see mental health not as a diagnosis to medicate, but as a system to understand and support.Dr. Taz and Dr. Greenblatt discuss:The gap between symptom focused care and root cause testingKey labs for mood, vitamin D, B12, iron, thyroid, hormonesWhy micronutrients come first for eating disordersMTHFR, methylfolate, glutathione, and antidepressant responseNutrigenomics for personalized vitamin and mineral dosingThe risks of quick med stacking and 10 minute checksWhere ketamine, psychedelics, and lithium orotate may help, and when they do notADHD, ultra processed foods, sugary drinks, sleep, and screen timeAbout Dr. James Greenblatt, MDDr. James Greenblatt, MD is a board certified psychiatrist and a pioneer of integrative and nutritional psychiatry. For more than three decades he has treated patients with ADHD, depression, anxiety, and eating disorders using personalized protocols that combine conventional care with targeted nutrients and lab guided precision. He is the author of multiple books including Finally Focused and the upcoming Finally Hopeful.Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Dr. James Greenblatt MD: Website: https://jamesgreenblattmd.com Platform: https://PsychiatryRedefined.org Instagram: https://instagram.com/psychiatry_redefinedDon't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+00:00 Introduction, testing gap and the B12 tragedy01:31 Pharma model and 10 minute med checks02:37 Framing the crisis and why patients feel stuck05:49 How psychiatry arrived at symptom based meds07:29 What to test, hormones and core nutrients10:49 The Whole Body Map explained12:39 Vitamin D, B12, iron, thyroid, practical targets17:52 Why meds fail without nutrition18:23 Eating disorders, zinc, omega 3, methylfolate24:33 MTHFR, folate, and glutathione26:34 Nutrigenomics and personalized dosing29:51 Ketamine and psychedelics, proceed with caution32:26 Lithium orotate, irritability and dementia research38:57 Polypharmacy, slowing down, doing the work43:21 ADHD, diet, sleep, screens, lifestyle links46:28 Where to learn more, resources, closing (00:00) - Chapter 1 (00:00) - Introduction, testing gap and the B12 tragedy (01:31) - Pharma model and 10 minute med checks (02:37) - Framing the crisis and why patients feel stuck (05:49) - How psychiatry arrived at symptom based meds (07:29) - What to test, hormones and core nutrients (10:49) - The Whole Body Map explained (12:39) - Vitamin D, B12, iron, thyroid, practical targets (17:52) - Why meds fail without nutrition (18:23) - Eating disorders, zinc, omega 3, methylfolate (24:33) - MTHFR, folate, and glutathione (26:34) - Nutrigenomics and personalized dosing (29:51) - Ketamine and psychedelics, proceed with caution (32:26) - Lithium orotate, irritability and dementia research (38:57) - Polypharmacy, slowing down, doing the work (43:21) - ADHD, diet, sleep, screens, lifestyle links (46:28) - Where to learn more, resources, closing

In episode 506 I chat with Dr Sam Greenblatt. Sam is a licensed clinical psychologist.  We discuss an update on him, relationship OCD (ROCD) using his personal story as a case study, improving ROCD treatment, exposure and response prevention therapy (ERP), internal family systems (IFS) therapy, working with other emotions around ROCD, feeling emotions without analysing them, improving relationships, and much more. Hope it helps. Show notes: https://theocdstories.com/episode/sam-506 The podcast is made possible by NOCD. NOCD offers effective, convenient therapy available in the US and outside the US. To find out more about NOCD, their therapy plans and if they currently take your insurance head over to https://go.treatmyocd.com/theocdstories Join many other listeners getting our weekly emails. Never miss a podcast episode or update: https://theocdstories.com/newsletter 

The Elizabethan playwright Christopher Marlowe is known as Shakespeare's greatest rival. But in his new book Dark Renaissance, historian Stephen Greenblatt makes the case that Marlowe paved the way for Shakespeare. In today's episode, Greenblatt joins NPR's Ari Shapiro for a conversation about what made Marlowe a “lost soul,” how the playwright navigated a world of intense censorship, and evidence that points to his role as a spy.To listen to Book of the Day sponsor-free and support NPR's book coverage, sign up for Book of the Day+ at plus.npr.org/bookofthedayLearn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Christopher Marlowe and William Shakespeare were both born in 1564, rising from working-class origins finding success in the new world of the theater. But before Shakespeare transformed English drama, Marlowe had already done so—with Tamburlaine the Great and the introduction of blank verse to the stage. As Stephen Greenblatt argues in his new biography, Dark Renaissance: The Dangerous Times and Fatal Genius of Shakespeare's Greatest Rival, virtually everything in the Elizabethan theater can be seen as “pre- and post-Tamburlaine.” Shakespeare learned from Marlowe, borrowed from him, and even tried to outdo him. Beyond his theatrical innovation, Marlowe was a poet, provocateur, and likely spy whose turbulent life was cut tragically short. In this episode, Greenblatt explores Marlowe's audacious works, his entanglements with power and secrecy, and his lasting influence on Shakespeare and the stage. From the Shakespeare Unlimited podcast. Published September 23, 2025. © Folger Shakespeare Library. All rights reserved. This episode was produced by Matt Frassica. Garland Scott is the executive producer. It was edited by Gail Kern Paster. We had help with web production from Paola García Acuña. Leonor Fernandez edits our transcripts. Final mixing services are provided by Clean Cuts at Three Seas, Inc. Stephen Greenblatt is Cogan University Professor of the Humanities at Harvard University. He has written extensively on English Renaissance literature and acts as general editor of The Norton Anthology of English Literature and The Norton Shakespeare. He is the author of fourteen books, including The Swerve, winner of the Pulitzer Prize and National Book Award, and Will in the World, a Pulitzer Prize finalist.