Podcasts about ischemic heart disease

Focus Issue on Ischemic Heart Disease, Thrombosis and Antithrombotic Therapies

In this Healthed lecture, Associate Professor Stephan Foy will provide a practical framework for investigating these patients as they present in general practice.See omnystudio.com/listener for privacy information.

Mamas Mamas, DPhil, MA, MBBCh and Joerg Herrmann, MD discuss the care of patients with ischemic heart disease and cancer.

Commentary by Dr. Candice Silversides

Commentary by Dr. Valentin Fuster

Special guest Dave L. Dixon, PharmD, FACC, FAHA, FCCP, FNLA, BCACP, CDCES, CLS, the Nancy L. and Ronald H. McFarlane Professor of Pharmacy and Chair of the Department of Pharmacotherapy & Outcomes Science at the Virginia Commonwealth University School of Pharmacy, joins us to talk about chronic coronary disease.Listen in as he discusses the management of chronic coronary disease with a focus on the new American College of Cardiology/American Heart Association guidelines.You'll also hear practical advice from panelists on TRC's Editorial Advisory Board:Anthony A. Donato, Jr., MD, MHPE, Associate Program Director, Tower Health System Internal Medicine Residency Program and Professor of Medicine at the Drexel University College of MedicineSteven E. Nissen, MD, MACC, the Chief Academic Officer at the Heart and Vascular Institute and the Lewis and Patricia Dickey Chair in Cardiovascular Medicine Professor of Medicine at the Cleveland Clinic Lerner School of Medicine at Case Western Reserve UniversityCraig D. Williams, PharmD, FNLA, BCPS, Clinical Professor of Pharmacy Practice at the Oregon Health and Science UniversityFor the purposes of disclosure, Dr. Dixon reports a relevant financial relationship [GLP-1 agonists, SGLT2 inhibitors] with Boehringer Ingelheim (grants/research support). Dr. Steven Nissen reports relevant financial relationships [cardiology] with AbbVie, Amgen, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Esperion, Medtronic, MyoKardia, New Amsterdam Pharma, Novartis, Pfizer, Silence Therapeutics (grants/research support).The other speakers have nothing to disclose. All relevant financial relationships have been mitigated.TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist's Letter or Prescriber's Letter account and look for the title of this podcast in the list of available CE courses.The clinical resources mentioned during the podcast are part of a subscription to Pharmacist's Letter and Prescriber's Letter: Toolbox: Optimizing Care of Patients with Coronary Artery DiseaseChart:  Dual Antiplatelet Therapy for Coronary Artery DiseaseChart:  Treatment of HypertensionIf you're not yet a Pharmacist's Letter or Prescriber's Letter subscriber, find out more about our product offerings at trchealthcare.com. Follow or subscribe, rate, and review this show in your favorite podcast app. You can also reach out to provide feedback or make suggestions by emailing us at ContactUs@trchealthcare.com.

What does the cutting edge of radiation oncology look like for treating triple-negative breast cancer? Tune in to hear experts Drs Kevin Kalinsky and Reshma Jagsi discuss. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/991257). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources A Review of Triple-negative Breast Cancer https://www.medscape.com/viewarticle/727195_4 A Review of the Abscopal Effect in the Era of Immunotherapy https://pubmed.ncbi.nlm.nih.gov/36321062/ The Impact of Radiation-induced DNA Damage on cGAS-STING-mediated Immune Responses to Cancer https://pubmed.ncbi.nlm.nih.gov/33238631/ Gray (Gy) https://www.nrc.gov/reading-rm/basic-ref/glossary/gray-gy.html Event-free Survival With Pembrolizumab in Early Triple-negative Breast Cancer https://pubmed.ncbi.nlm.nih.gov/35139274/ Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-negative Breast Cancer https://clinicaltrials.gov/study/NCT02954874 Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD) https://clinicaltrials.gov/study/NCT04443348 Translational Breast Cancer Research Consortium (TBCRC) https://tbcrc.org/ Emerging Role of PARP Inhibitors in Metastatic Triple Negative Breast Cancer. Current Scenario and Future Perspectives https://pubmed.ncbi.nlm.nih.gov/34900718/ SWOG Cancer Research Network https://www.swog.org/ BRCA1 and BRCA2 Mutations https://www.ncbi.nlm.nih.gov/books/NBK470239/ Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study https://pubmed.ncbi.nlm.nih.gov/29558281/ Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer https://clinicaltrials.gov/study/NCT03598257 Breast Cancer and HER2 https://emedicine.medscape.com/article/1689966-overview ER/PgR Testing in Breast Cancer Clinical Practice Guidelines (ASCO/CAP, 2020) https://reference.medscape.com/viewarticle/924542 Oncotype DX Breast Recurrence Score®: A Review of Its Use in Early-stage Breast Cancer https://pubmed.ncbi.nlm.nih.gov/32613290/ Regional Radiotherapy in Biomarker Low-risk Node Positive and T3N0 Breast Cancer (TAILOR RT) https://classic.clinicaltrials.gov/ct2/show/NCT03488693 Postoperative Radiotherapy in High-risk Premenopausal Women With Breast Cancer Who Receive Adjuvant Chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial https://pubmed.ncbi.nlm.nih.gov/9395428/ Postoperative Radiotherapy in High-risk Postmenopausal Breast-cancer Patients Given Adjuvant Tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c Randomised Trial https://pubmed.ncbi.nlm.nih.gov/10335782/ Risk of Ischemic Heart Disease in Women After Radiotherapy for Breast Cancer https://pubmed.ncbi.nlm.nih.gov/23484825/ Radiotherapy Use and Incidence of Locoregional Recurrence in Patients With Favorable-risk, Node-positive Breast Cancer Enrolled in the SWOG S1007 Trial https://pubmed.ncbi.nlm.nih.gov/37410451/

In this post, we will focus on VA service-connected compensation ratings for heart disease in general.   You need to know what VA needs to have in order to assign the proper disability rating for your disease, so you can obtain VA disability compensation. If you are a Vietnam Veteran seeking information on ischemic heart disease, the U.S. Department of Veterans Affairs has allowed presumptive service connected compensation to Vietnam veterans for IHD (ischemic heart disease). Check out this post on Ischemic Heart Disease from Agent Orange.

Commentary by Dr. Candice Silversides

Commentary by Dr Jae-Sik Jang

Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Early invasive strategy does not reduce mortality for moderate to severe ischemic heart disease after 5.8 years (ISCHEMIA-EXTEND) '

Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Percutaneous coronary intervention does not improve outcomes for patients with ischemic heart disease and LVEF of less than 35% '

In this episode of the podcast, Andrew Perry chats with Dr. Amanda Eng to discuss the paper “Long working hours, sedentary work, noise, night shifts and risk of ischaemic heart disease.” If you enjoy the show, please subscribe to the podcast to get episodes automatically downloaded to your phone and computer. Also, please consider leaving us a review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 Link to published paper: https://heart.bmj.com/content/early/2022/08/24/heartjnl-2022-320999

How an early-'90s newsmagazine show convinced a generation of Americans to start drinking red wine. For the antioxidants! Special thanks to Susanne Stolpe and Alexander H. Sandtorv for helping us fact-check this episode! Support us:Hear bonus episodes on PatreonDonate on PayPalGet Maintenance Phase T-shirts, stickers and moreLinks!Diet and alcohol in heart disease risk: the French ParadoxAbsorption of three wine-related polyphenols in three different matrices by healthy subjectsFrom red wine to polyphenols and back: A journey through the history of the French ParadoxWine as a Biological Fluid: History, Production, and Role in Disease PreventionCardiovascular Risk Factors and Confounders Among Nondrinking and Moderate-Drinking U.S. AdultsAlcohol, Drinking Pattern, and Chronic DiseaseThe French paradox: lessons for other countriesMyocardial Infarction and Coronary Deaths in the World Health Organization MONICA ProjectCoronary heart disease in France and in Europe: Where are the facts?Wine And Juice Management And Marketing Decisions: The Case Of The French ParadoxDecline of coronary heart disease mortality is strongly effected by changing patterns of underlying causes of deathThe Medical Autopsy: Past, Present, and Dubious FutureNew dimensions in cause of death statisticsShould socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers?Wine, alcohol, platelets, and the French paradox for coronary heart diseaseAlcohol, Ischemic Heart Disease, and the French Paradox Death certificates are not reliable: revivification of the autopsy Thanks to Doctor Dreamchip for our lovely theme song!Support the show

Looking for more information on this topic? Check out the Ischemic Heart Disease: Foundations and Frameworks brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

Commentary by Dr. Valentin Fuster

Contemporary Topics in SCAD Guest: Marysia S. Tweet, M.D., M.S. (@marysia_tweet) Host: Malcolm R. Bell, M.D. SCAD, also known as Spontaneous Coronary Artery Dissection, is defined as a tear in an artery wall within the heart, which decreases blood flow to the heart. In addition, patients without treatment are at risk of having a heart attack or chances of experiencing cardiac arrest. 90% of SCAD cases were found in women. However, men can also experience SCAD. Some triggers that can lead to SCAD are intense weightlifting, severe high blood pressure, emotional stress, and more. Joining us today to discuss Contemporary Topics in SCAD is Marysia S. Tweet, M.D., M.S associate professor of medicine and consultant in the Division of Ischemic Heart Disease as well as joint appointment in the Division of Cardiovascular Ultrasound at Mayo Clinic in Rochester, Minnesota. Specific topics discussed: What do you tell patients when they ask will SCAD happen again? How do you advise regarding exercise after SCAD? What do you tell women of childbearing age regarding future pregnancy after SCAD? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV. NEW Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.

Ron Waksman, MD; Spencer B. King, III, MD; Gary S. Mintz, MD; and Ashish Kumar, MD

The discussion over what aspect of our diet has been driving the escalation of metabolic disease over the last 100 years has been a confusing one full of contradictory information. It would be logical to look for a change in our diet associated with such a dramatic change in the health of a population There are both correlated evidence and dietary trials to support the theory that the increase in linoleic acid, provided by the introduction of PUFA processed oils into our diet, is the driver. In this episode of Hunger Hunt Feast, I want to share a collection of them to help clarify some of the confusion. -- Episode Specific Links:  Linoleic acid concentrations in fats and oils http://www.distributionkatrina.com/english/comparison-of-dietary-fats.html Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half-Century https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4642429/ Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla https://www.sciencedirect.com/science/article/pii/S0022227520346733 Diets could prevent many diseases https://www.researchgate.net/publication/10673140_Diets_could_prevent_many_diseases Corn Oil in Treatment of Ischemic Heart Disease https://ncbi.nlm.nih.gov/pmc/articles/PMC2166702/ Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse https://pubmed.ncbi.nlm.nih.gov/27886622/#:~:text=the%20male%20mouse-,Linoleic%20acid%20causes%20greater%20weight%20gain%20than%20saturated%20fat%20without,doi%3A%2010.1016%2Fj Effects of fatty acids on mitochondria: implications for cell death https://pubmed.ncbi.nlm.nih.gov/12206909/ Can linoleic acid contribute to coronary artery disease? https://pubmed.ncbi.nlm.nih.gov/8192728/ Effects of linoleate-enriched and oleate-enriched diets in combination with alpha-tocopherol on the susceptibility of LDL and LDL subfractions to oxidative modification in humans https://pubmed.ncbi.nlm.nih.gov/8148354/ Acrolein is a product of lipid peroxidation reaction https://www.jbc.org/article/S0021-9258(18)80708-6/fulltext#seccestitle90 The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis https://pubmed.ncbi.nlm.nih.gov/16270280/ Rapeseed oil and sunflower oil diets enhance platelet in vitro aggregation and thromboxane production in healthy men when compared with milk fat or habitual diets https://pubmed.ncbi.nlm.nih.gov/1641826/ Stearoyl-CoA Desaturase-1 Is Associated with Insulin Resistance in Morbidly Obese Subjects https://link.springer.com/article/10.2119/molmed.2010.00078 Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/ Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/ Role of Physiological Levels of 4-Hydroxynonenal on Adipocyte Biology: Implications for Obesity and Metabolic Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038367/ “The Hateful Eight: Enemy Fats That Destroy Your Health - Dr. Cate.” Dr. Cate, 22 May 2020,  https://drcate.com/the-hateful-eight-enemy-fats-that-destroy-your-health/ Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6180905/ Strong increase in hydroxy fatty acids derived from linoleic acid in human low-density lipoproteins of atherosclerotic patients https://pubmed.ncbi.nlm.nih.gov/9488997/ Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA https://journals.physiology.org/doi/full/10.1152/ajpheart.00480.2004?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org Changes in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a) https://pubmed.ncbi.nlm.nih.gov/9844997/ “Dr. Knobbe Presents, ‘Macular Degeneration - Preventable & Treatable - With an Ancestral Diet?' at Weston A. Price Foundation's Annual Conference - Wise Traditions - 2017 - Cure AMD Foundation.” Cure AMD Foundation, https://www.cureamd.org/dr-knobbe-presents-macular-degeneration-preventable-treatable-with-an-ancestral-diet-at-weston-a-price-foundations-annual-conference-wise-traditions-2017/ Unsaturated fatty acids and their oxidation products stimulate CD36 expression in human macrophages https://www.researchgate.net/publication/11260045_Unsaturated_fatty_acids_and_their_oxidation_products_stimulate_CD36_expression_in_human_macrophages Lowering dietary linoleic acid (LA) reduces bioactive oxidized linoleic acid metabolites in humans https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3467319/ Can linoleic acid contribute to coronary artery disease? https://www.researchgate.net/publication/15005994_Can_linoleic_acid_contribute_to_coronary_artery_disease A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://pubmed.ncbi.nlm.nih.gov/9844997/ Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2012.38 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis https://www.bmj.com/content/346/bmj.e8707 Connect with Zane: ReLyte Electrolytes by Redmond Real Salt: https://shop.redmond.life?afmc=Zane Follow me on Instagram: https://www.instagram.com/zanegriggsfitness Follow me on YouTube: https://www.youtube.com/c/ZaneGriggs QUICK EPISODE SUMMARY What causes modern disease The hateful eight oils The correlation between vegetable oils and obesity The oxidation effects of LDL The truth about the dairy data How much cholesterol is in your brain  Where you can find a copy of today's mentioned study What we know about Linoleic acid

Commentary by Dr. Valentin Fuster

Commentary by Dr. Valentin Fuster

What are the long-term cardiovascular outcomes of COVID-19? Find out about this and more in today's PV Roundup podcast.

There is a Global Cardiovascular Disease Epidemic. Ischemic Heart Disease is the leading cause for early death as per the Global Burden of Disease, 2017. Mortality from cardiovascular diseases (CVD) worldwide has increased since 2007 , is another finding in this report. Multimodality Imaging is important for the diagnosis, the prognostic assessment and for guiding therapy. It provides a comprehensive evaluation of all the issues related to multiple cardiovascular diseases. Increased use of diagnostic imaging has increased the pressure on Cardiac Imagers and Cardiovascular Radiology workflows. There is also a shortage of Cardiac Imagers to visually read and interpret the patient studies. The OneCardio© AI-driven Cardiac Imaging Analyses platform provides the essential tools for segmentation, quantification and radiomics to Cardiac Imagers and prescribing Clinicians to drive workflow improvements for improving productivity, treatment and patient outcomes. For more information, visit https://hearthealthtech.com/ If you have the next big idea, apply to the Expert Dojo Accelerator: www.expertdojo.com

If you are interested in lipids, you've probably heard of Dave Feldman and his work. If not,  you've got some homework to do, and I think you'll be  amazed at what you find. Dave's work can be found at cholesterolcode.com where he details his multiple, meticulous self-experimental projects. Prior to cholesterol adventures Dave was a senior software scientist and an engineer. He brings this “out of the box” thinking to the world of medicine and we are all better off for it.  He began a low-carb, high-fat diet in April 2015 and has since learned everything he could about it with special emphasis on cholesterol. He saw his own lipid numbers spike substantially after going on the diet and spotted a pattern in the lipid system that's very similar to distributed objects in networks.  Time Stamps: 0:09:20 Podcast begins with Dave Feldman 0:09:45 Responding to the common question: "I feel so good on Animal-Based, but my cholesterol is sky high. What's going on?" 0:20:05 The importance of context in regards to cholesterol  0:26:20 Just because cholesterol is involved in asc sclerosis, that does not mean it is the cause of asc sclerosis 0:33:50 Inflammation and it's role with asc sclerosis 0:36:00 Do we have any experiments that shows LDL is directly harmful to humans? 0:47:05 The more saturated fat you eat, the higher your LDL goes, but does this result in more chronic disease? 0:57:35 PUFA's are essential for humans, but if you're eating saturated fat from grass-fed ruminant animals, you will not become deficient  1:02:44 Familial hypercholesterolemia (FH) and healthy individuals 1:07:40 Macrophages of genetically characterized familial hypercholesterolaemia patients show up‐regulation of LDL‐receptor‐related proteins: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323824/ 1:14:20 A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991918/ 1:15:20 Chimpanzee VS Human LDL 1:15:45 Chimpanzee serum lipoproteins. Isolation, characterisation and comparative aspects of the low density lipoprotein and apolipoprotein-BH: https://pubmed.ncbi.nlm.nih.gov/6477668/ 1:25:05 Distribution of glycosaminoglycans in the intima of human aortas: changes in atherosclerosis and diabetes mellitus: https://pubmed.ncbi.nlm.nih.gov/8477876/ 1:29:20 The importance of hemostasis and how it relates to blood clots 1:35:40 Xanthoma in lean-mass hyper responders who do not have FH 1:40:50 Low Triglycerides–High High-Density Lipoprotein Cholesterol and Risk of Ischemic Heart Disease: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/647239 1:44:00 Hyperlipidaemia does not impair vascular endothelial function in glycogen storage disease type 1a: https://linkinghub.elsevier.com/retrieve/pii/0021915094900728 1:47:35 If a patient has a rising LDL, but is otherwise healthy, what does Dave suggest? 1:53:00 https://citizensciencefoundation.org/ and where to find more of Dave's work 1:54:30 Dave's current diet Sponsors: Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order Belcampo: www.belcampo.com use code: CarnivoreMD for 20% off your order Lets Get Checked: 20% off your order at www.TRYLGC.com/paul

Walking is a brilliant form of exercise but it's often overlooked in favour of running or yoga or HIIT workouts. Because we are exercise sloths and busy women, we're always looking for quick and easy ways to get moving. If you're trying to get fit and healthy, walking is one of the most accessible types of exercise you can do. Gab and Sarah look at some good quality research which shows why walking is really, really good for you. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Sarah's Burpees for Boobs Sydney Breast Cancer Foundation fundraiser Walking for hypertension Association of Step Volume and Intensity With All-Cause Mortality in Older Women Kathy Smith power walking audio workout Waking Up with Sam Harris Heavyweight podcast WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Have you ever tried Pilates? It's a popular form of exercise that was developed by Joseph Pilates in the early 20th century.  It's now a worldwide fitness trend and it's often used as a form of rehabilitation for lower back pain or injury, and recovery after childbirth.  Gab and Sarah look at what Pilates actually involves and if it lives up to the hype. Plus, another batshit crazy fitness trend, this time involving Kate Hudson and a bag full of water.  Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Cochrane Library Pilates for low back pain Jessica Valant - Gentle Pilates 15 Minute Pilates for Beginners Workout WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

How many times have you set yourself a big fitness goal? Did you achieve it? Research shows that having really specific and fixed goals can actually be a deterrent rather than a motivator.  In recent years there's been a shift away from the traditional method of goal-setting known as SMART goals (specific, measurable, achievable, realistic and timebound); towards a more flexible approach. Gab and Sarah explain the idea behind ‘open goals', and how this is proving to be a more effective way of achieving a fitness target. You'll also hear about the world record for planking, and a review of Maddie Lymburner's Low Impact Full Body HIIT workout. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: ABC Try setting an open goal for your New Year's resolution if you want to exercise more  MadFit Low Impact FULL BODY HIIT Workout (No Equipment + No Jumping) Yoga With Adriene Wind Down Yoga (12 minute bedtime yoga) WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

No matter how hard you try, it can often feel like your fitness isn't improving. It's so disappointing when you've been doing the same workouts over and over and you don't see any progress in your strength, or number of reps, or cardiovascular fitness. Even when you've been consistent with your exercise, sometimes it feels like you've hit a wall and you can't get past it. So what do you do when your progress has stalled? Gab and Sarah explain how to reframe the way you measure progress, and look for the many ways you are making headway (even when it doesn't feel like it). Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Sports Bras Direct Yoga With Adriene Morning Yoga Flow (22mins) Nike Run Club ‘Don't Wanna Run Run' WLY Spotify playlist Over Ear Earbuds (example only - we have not tried this particular brand) MadFit low Impact FULL BODY HIIT Workout (No Equipment + No Jumping) The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

This episode we're talking endocannabinoids and sports bras (the two are not related!). For years it was thought that the “runner's high” was due to the release of endorphins.  Endorphins are chemicals that are produced by the body to relieve stress and pain, and they work on the opioid receptors in the brain (the same receptors that opiate drugs like morphine act upon). An increasing body of evidence suggests that this so-called “runner's high” is notdue to the release of endorphins but is instead due to the release of another type of neurochemical called endocannabinoids. And yes, the word endocannabinoid sounds a lot like the word cannabis, and in the same way that endorphins act upon the opiate receptors in the brain, endocannabinoids act upon the same cannabinoid pathways as cannabis.   Sarah explains why it's theoretically possible to get a little “high” on exercise, and Gab has some sports bra recommendations for you to check out. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Neuromodulation of Aerobic Exercise—A ReviewSerum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder Sports Bras Direct Bra fitting guide Yoga With Adriene Morning Yoga Flow (22mins) Nike Run Club ‘Don't Wanna Run Run' WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Did you know you release stress hormones when you exercise? It's because your body is in a state of physical stress, especially if you're new to exercise or you're not an adrenaline junkie. It's the reason why you feel so gross during a workout.  The good news is, regular exercise trains your body to cope better with these stress hormones, which can help build your resiliency to other forms of stress. Gab and Sarah explain why exercise is a useful tool for looking after your mental health. Plus, Sarah has a new hobby and Gab has another weekly challenge for you. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: YouTube 7 minute workout video Concept2 BikeErg exercise bike Momentum Habit Tracker Impala Skates Huberman Lab podcast Nike Run Club ‘Don't Wanna Run Run' WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

It's episode 10 baby! We've reached a small but meaningful milestone and it feels like the perfect time for a quick refresh. If the shine has worn off and you've lost your motivation for exercise, that's ok! Gab and Sarah are here to get you back on track with some key tips for building a daily exercise habit. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Atomic Habits by James Clear  Nike Run Club WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Do you listen to music when you exercise? For Gab and Sarah, a banging playlist is essential. Sometimes the only way to stay motivated during a workout is to turn up the volume and focus on the tunes. Gab and Sarah look at a new study which explains a link between music and exercise, and a beautiful email from a WLY mum. Did you know you can subscribe to the Women Like You newsletter? If you'd like to be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Concept2 BikeErg exercise bike MadFit Dua Lipa Dance Party workout University of Edinburgh Running to music helps combat mental fatigue Nike Run Club Spotify WLY workout playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

If you've wasted money on fitness products you never used, you're not alone. Gab and Sarah have dropped plenty of dough on exercise fads and gym memberships over the years. This week they share some of their favourite fitness apps and workouts that will cost you absolutely nothing. WLY resources and recommendations: Cervical Screening (CST) in Australia pamphlet Concept2 BikeErg exercise bike Yoga With Adriene  MadFit with Maddie Lymburner  MadFit Dua Lipa Dance Party workout Nike Run Club ‘Mindful' Guided Runs Momentum Habit Tracker Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

What dumb things have you done to try and get fit? Gab and Sarah share their hilarious exercise horror stories and the stupid things they've done in the name of fitness. You'll hear about the time Gab did CrossFit for a month, and how Sarah once vomited in a PT session. WLY fitness survey + newsletter subscription Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

How often do you criticise yourself? When it comes to exercise, we can be way too hard on ourselves. We might believe things like we're not ‘sporty', or that we don't have any athletic ability. Most of these ‘beliefs' come from things people have said to us and have no basis in reality. Gab and Sarah tackle negative self-talk and why what you say to yourself matters. WLY resources and recommendations: YouTube 7 minute workout video The 7 minute work-out explained Australian type 2 diabetes risk assessment tool AUSDRISK calculator  CSIRO Total wellbeing diet How To Do The Work by Dr Nicole LePera Headspace Guide to Meditation - Netflix Waking Up app by Sam Harris  Making Sense with Sam Harris podcast  Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Forget about exercising for a ‘bikini body', it's time to start thinking about your health. Did you know diabetes is the world's fastest growing chronic health condition? One of Gab's friends (a seemingly healthy 30-something) has just been diagnosed with type 2 diabetes. Sarah explains the key risk factors to watch out for and why exercise is so important for keeping you healthy.   WLY resources and recommendations: COVID-19 Vaccine Eligibility Checker YouTube Box breathing video YouTube 7 minute workout video The 7 minute work-out explained Australian type 2 diabetes risk assessment tool AUSDRISK calculator  Keune Style Dry Texturizer WLY fitness survey + newsletter subscription Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

68% of the Women Like You community said lack of motivation was their biggest challenge. Gab and Sarah introduce you to their ‘Out of 10 Rule' which will help you stay on track even when you have zero motivation to work out. This neat little trick is the reason they've been able to keep up a regular exercise habit for the first time ever. WLY resources and recommendations: YouTube 7 minute workout video The 7 minute work-out explained WLY fitness survey + newsletter subscription Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Finding time to exercise is hard. Between work, relationships, home life, raising children, making time for friends, caring for ageing parents (while living through a global pandemic) there aren't enough hours in a day. Gab and Sarah explain the minimum amount of moderate intensity activity you need to do each week. WLY resources and recommendations: Australian Government Department of Health Physical Activity and Exercise Guidelines  ABC News ‘What's the minimum amount of exercise you need to stay healthy?' The 7 minute work-out Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Why is it so hard to exercise regularly? You know it's good for you. You know it will improve your mental and physical wellbeing, and you know it can help prevent chronic health conditions. So why don't you do it? Gab and Sarah explain why you're not lazy, you're genetically adapted to rest. WLY resources and recommendations: Australian Institute of Health and Welfare - Insufficient Physical Activity reporthttps://bit.ly/3A36Wm9  Prof. Daniel Lieberman ‘Is Exercise Really Medicine? An Evolutionary Perspective'https://bit.ly/3dl4sWN   The Guardian ‘Is your willpower failing? I tried hypnotherapy – and it worked almost too well' The Guilty Feministhttps://guiltyfeminist.com/   Contact us: womenlikeyoupodcast@gmail.com The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Myocardial Blood Flow Assessed With PET Scanning in the Evaluation of Patients With Chest Pain Guest: John P. Bois, M.D. Host: Malcolm R. Bell, M.D.  What is typically seen in positron emission tomography (PET) imaging is qualitative: Before and after pictures of patients at rest and under stress that are used to identify any kind of relative profusion defects. Quantitative PET takes this technique a step further, quantifying blood flow to the heart tissue in milliliters per minute per gram of myocardial tissue. In essence, traditional PET takes a photo of the heart before and after, but qualitative PET produces a video of the blood flow into the heart over time. Joining us today to discuss myocardial blood flow and coronary flow reserve as assessed with PET scanning in the evaluation of patients with chest pain is John P. Bois, M.D., a consultant in Ischemic Heart Disease and Critical Care with a joint appointment in Radiology here at Mayo Clinic in Rochester, Minnesota. He's also co-director of our Chest Pain and Coronary Physiology Clinic, a nuclear cardiology specialist and an assistant professor of medicine. Specific topics discussed: Quantitative versus qualitative PET: Quantifying blood flow to the heart tissue Automatic quantification via mathematical modeling Quantitative PET in patients with obstructive artery disease Improved testing accuracy with quantitative PET Diagnostic and prognostic evaluation of patients with challenging symptoms Future applications: standardization ad studies Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV. No CME credit offered for this episode. Podcast transcript can be found here.

A postmortem report on the death of Archbishop Dr. Cyprian Kizito Lwanga indicates that he succumbed to Ischemic Heart disease, ruling out murder speculations going around.

This episode covers ischemic heart disease!

Metoprolol is an anti-anginal, anti-hypertensive agent that works by selectively inhibiting the beta1 adrenergic receptor. Some of the brand names are Lopressor, Toprol XL, and Kapspargo Sprinkle. Dosing may vary based on if the formulation is the IR or ER form and by indication. For Angina in adults the IR tartrate form starts at 50 mg po bid with weekly increases to a max of 400 mg/day. There is a black box warning for Ischemic Heart Disease warning that abrupt cessation of therapy may harm patients and if therapy is to be discontinued, the patient should be titrated down over 1-2 weeks. The most common side effect is orthostatic hypotension. Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you'd like to say hello, suggest a drug, or leave some feedback I'd really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily --- Send in a voice message: https://anchor.fm/drugcardsdaily/message

This episode covers ischemic heart disease!

Drs. Ron Waksman and Renato Lopes discuss the results of a study presented as a late-breaking trial at the European Society of Cardiology 2020 virtual congress. This study examined whether medical therapy or more or an invasive strategy was better for patients with intermediate heart failure (ejection fraction of 35% to 45%) and stable ischemic heart disease. When compared with patients with ischemia but without heart failure, stable ischemic patients with heart failure saw a benefit from invasive intervention. Watch the interview on CRTonline

Antiplatelet therapy is a mainstay treatment for the prevention of recurrent cardiovascular events in patients with stable coronary artery disease (CAD). Anticoagulation therapy is the cornerstone of therapy for most patients with atrial fibrillation (AF). AF and CAD are frequent comorbid conditions, occurring in 20-30% of patients with stable CAD. Unfortunately, combining antiplatelet and anticoagulation therapy increases the risk of major bleeding over 50% compared to anticoagulation alone. Recent real-world observational data suggest that direct oral anticoagulation (DOACs) therapy can reduce cardiovascular event rates. This begs the question: In patients with stable CAD and AF, is combination therapy necessary or is anticoagulation monotherapy sufficient?  The AFIRE study attempted to address this important clinical question. Guest Authors: Alina Kukin, PharmD and Zachary R. Noel, PharmD, BCCP Music by Good Talk

    The number of Americans suffering from atrial fibrillation is soaring and the treatment varies from medication to a variety of surgical procedures. We'll discuss the latest options.    A new study shows that if you want to lower your blood pressure, walking is good, but fast walking is better.    Your triglyceride level helps a doctor predict the risk of heart disease. And this week two big studies indicated there may be a much better way of measuring triglycerides than the one they have been using. “Heart therapy strains efforts to limit costs.? The New York Times, July 7, 2007http://www.nytimes.com/2007/07/07/health/07heart.html?ex=1185336000&en=d636fe3ce0c28ce3&ei=5070  Fast walking is better for improving systolic blood pressure in older adults. www.medpagetoday.com, posted July 12, 2007http://www.medpagetoday.com/PrimaryCare/ExerciseFitness/tb/6145  “Blood triglycerides seen as heart attack predictor.? Reuters, July 17, 2007http://today.reuters.com/news/articlenews.aspx?type=healthNews&storyid=2007-07-17T215724Z_01_N17274797_RTRUKOC_0_US-HEART-TRIGLYCERIDES.xml  “Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women.? Journal of the American Medical Association, Vol. 298 No. 3, July 18, 2007http://jama.ama-assn.org/cgi/content/short/298/3/299  “Fasting Compared With Nonfasting Triglycerides and Risk of Cardiovascular Events in Women.? Journal of the American Medical Association, Vol. 298 No. 3, July 18, 2007http://jama.ama-assn.org/cgi/content/abstract/298/3/309?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=fasting+compared+with+nonfasting+triglycerides+and+risk&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT