Podcasts about Anandamide

Dr. Hoffman continues his conversation with Dr. Joseph Feuerstein, director of Integrative Medicine at Stamford Hospital.

There's apprehension about the rapid adoption of artificial intelligence (AI) and virtual reality (VR)—are we about to enter the dystopian future world of The Matrix? But today's guest discusses the innovative application of AI and VR to a common problem: menopausal hot flashes in women for whom estrogen is contraindicated because of the risk of cancer. Using a VR headset, menopausal women were presented guided imagery featuring cooling and relaxing suggestions. A pilot study showed it reduced the frequency and intensity of hot flashes, improved sleep quality, and enhanced overall well-being. Dr. Joseph Feuerstein discusses a comprehensive strategy for menopause, comprising acupuncture, natural products (Estrovera and Relizen), exercise and diet. Are soy isoflavones OK for relieving menopausal symptoms, even in breast cancer patients? Dr. Feuerstein is also co-author of "The Cannabinoid Cookbook," which is not merely a guidebook to marijuana edibles; instead, it focuses on the numerous foods that support the body's endocannabinoid system—Including cocoa, omega-3 fatty acids, turmeric, and truffles. These foods deliver compounds which confer a multiplicity of mood and anti-inflammatory benefits.

The Endocannabinoid System plays a crucial role in regulating cardiovascular, neurological, and immune functions through CB1 and CB2 receptors. • CB1 Activation: Associated with oxidative stress, inflammation, and increased cardiovascular risks such as myocardial infarction (MI), arrhythmias, and heart failure. • CB2 Activation: Primarily found in immune cells and linked to anti-inflammatory and protective cardiovascular effects. • Cannabis Use: High THC content or synthetic cannabinoids (e.g., Spice, K2) significantly increases the risk of cardiovascular diseases and psychiatric disorders. • Cannabis Use Disorder (CUD): Characterized by compulsive use despite adverse consequences, often co-occurring with depression, PTSD, and anxiety. • Potential Therapeutic Targets: CB1 antagonists (e.g., Genistein) and CB2 agonists are being explored for their ability to reduce inflammation and vascular damage while minimizing psychiatric side effects.   Future research is needed to clarify long-term cardiovascular effects, optimize cannabinoid therapies, and inform public health policies.

Pain isn't just something to avoid—it's a critical signal for growth and high performance. In this episode, we'll explore how pain plays a role in pushing limits, entering flow states, and achieving peak results. Plus, you'll learn practical strategies for reframing discomfort and using it as a tool for personal and professional growth. Key Takeaways:• ✅ Pain is a natural part of growth and peak performance.• ✅ Discomfort indicates you're operating at the edge of your abilities.• ✅ Physical pain can trigger neurochemicals that enhance mood and focus.• ✅ Reframing pain as an ally helps build resilience. Make sure to subscribe and follow me for updates, tips, and more ways to stay in the flow! You can connect with me on:• Instagram: @flow_network__• YouTube: @flow_network__• TikTok: @theflownetwork• LinkedIn Newsletter: Daily Flow Stay tuned for more great content, and as always, stay in the flow!

In this episode, my guest is Dr. Matthew Hill, Ph.D., a professor of cell biology and anatomy at the Hotchkiss Brain Institute at the University of Calgary and an expert on the biology of cannabis. We discuss how cannabis affects the brain to produce its psychoactive effects (feeling “high”), including altered time perception, focus, memory, appetite, and stress. We discuss how THC vs. cannabidiol (CBD) affects the brain, the effects of different routes of cannabis administration (e.g., smoking, vaping, edibles), high-potency THC, and whether cannabis is addictive. We discuss if there is a link between cannabis use and the development of psychosis, anxiety, bipolar depression, or schizophrenia.  We discuss whether CBD has clinical benefits in regulating stress, promoting sleep, and treating certain diseases. We also discuss if there are real and consistent differences in the biological effects of different cannabis strains, if cannabis impacts hormones, and the uses of cannabis for the management of pain, stress, Post-traumatic stress disorder (PTSD), anxiety, and nausea. Listeners of this episode will get an up-to-date understanding of what is currently known about how cannabis affects the brain and body, including both its potential benefits and risks. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://www.eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman BetterHelp: https://betterhelp.com/huberman InsideTracker: https://insidetracker.com/huberman Timestamps 00:00:00 Dr. Matthew Hill 00:00:00 Sponsors: Eight Sleep, LMNT & BetterHelp 00:07:16 Cannabis, THC, Cannabidiol (CBD), Terpenes 00:12:08 Psychoactive Effects, Cannabis “High”; Time Perception 00:16:55 Cannabis & Brain, CB1 Receptor, Endocannabinoids 00:26:19 Endocannabinoids Types: Anandamide, 2-AG 00:33:46 “Munchies”, Cannabis & Appetite 00:42:17 Sponsor: AG1 00:44:06 THC & Anandamide, Pharmacology 00:52:37 THC & CB1 Receptors, Intoxication & Appetite 00:58:57 Cannabis & Focus, Memory 01:04:09 Routes of Administration, Concentration, Cannabis Research 01:15:12 Self-Regulation, Inhalation & THC, Tolerance; THC Concentrates 01:22:25 Sponsor: InsideTracker 01:23:36 Addiction & Cannabis, Cannabis Use Disorder 01:31:30 Cannabis Legalization & Use, Edibles & ER Visits 01:36:48 Oral Consumption, Edibles, Dosing & Time Course 01:41:12 Drug Testing & Cannabis, Exercise 01:46:04 Cannabis & Hormones, Gynecomastia, Sperm Quality 01:54:37 Cannabis & Pregnancy; Selling Recreational Cannabis 02:04:07 Vaping 02:07:05 Psychosis, Anxiety & Cannabis 02:17:17 Cannabis, Psychosis, Schizophrenia & Genetics 02:30:45 Cannabis Use & Schizophrenia, Manic Bipolar, THC Potency, Nicotine 02:40:37 Schizophrenia, Cannabis Legalization 02:45:06 Cannabis Strains, Indica, Sativa, Subjective Effects & Expectancy Bias 02:57:00 CBD, Pediatric Epilepsy, Adenosine 03:07:22 Entourage Effect; Placebo Effect, CBD & Doses 03:19:12 Cannabis Health Risks, Cardiovascular Risk, Schizophrenia  03:27:08 Cyclic Vomiting Syndrome & Hot Shower 03:31:30 Cannabis Benefits: Pain, Stress, Anxiety, Post-Traumatic Stress Disorder (PTSD) 03:40:18 Cannabis & Anxiety, Anandamide & Stress Response 03:45:55 Scientific Discussion, Clarification & Advancement 03:49:47 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer

 If you've ever wondered why I don't eat seed oils, this conversation will give you great insight. In this episode of "Cook with Real Food," we delve into the often-overlooked topic of seed oils with Zane Griggs, a renowned health expert, longevity coach, and author. With over 25 years in the health and fitness industry, Zane brings a wealth of knowledge, especially on how eliminating seed oils can significantly enhance one's health and well-being!  This episode offers a deep dive into the benefits of whole foods and the pitfalls of seed oils. Get ready to take notes and learn why cutting out seed oils could be the first crucial step in your journey toward optimal health and longevity!   LINKS: Home: https://www.cookwithrealfood.com Join the Private Community and get the Cook Real With Food Cookbook FREE your first Month!  Link: patreon.com/cookwithrealfood   Zane's Links: Instagram: https://www.instagram.com/zanegriggsfitness Book Link: https://amzn.to/3plfofO Podcast: https://www.youtube.com/@healthyaf   Hear Zane Talk More About This Topic On This Episode:  "The Shocking Truth About Seed Oils and Their Impact on Our Health" Link: https://www.youtube.com/watch?v=myXLLE8T_Z0     Thank You Zane, For The Additional Resourcses and Charts Mentioned Below:  Dr. Cate Shanahan's blog https://drcate.com/seed-oils/ Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half Century https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4642429/ Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/?fbclid=PAAaaGHjo-VupP3i1wJ4_mfsEXbRHVZdux0OyoiGoXPppgvb6fsmnzjCW-g_U Consumption of a high-fat diet rich in omega-6 PUFA for only 4 weeks instigates mitochondrial damage and causes cardiac dysfunction https://pubmed.ncbi.nlm.nih.gov/17023268/ 4-HNE, a byproduct of linoleic acid directly correlates with obesity, growth of visceral fat and insulin resistance. https://pubmed.ncbi.nlm.nih.gov/28088621/ Linoleic acid can cause endothelial dysfunction. More linoleic acid is seen in the LDL of people with type 2 diabetes. https://diabetesjournals.org/diabetes/article/54/5/1506/25939/Linoleic-Acid-Increases-Lectin-Like-Oxidized-LDL#ref-13 The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis https://pubmed.ncbi.nlm.nih.gov/16270280/

Looking 4 Healing Radio with Dr. Henry Ealy – Discover the secret to waking up happy and excited every day! I guide you through mastering your perception to control the release of Dopamine & Anandamide, the Bliss Molecules. Learn to prioritize family, faith, and self-care, transforming your daily life into a journey of happiness and purpose. It's about giving yourself permission to be joyous. Join me and unlock your body's natural...

Looking 4 Healing Radio with Dr. Henry Ealy – Discover the secret to waking up happy and excited every day! I guide you through mastering your perception to control the release of Dopamine & Anandamide, the Bliss Molecules. Learn to prioritize family, faith, and self-care, transforming your daily life into a journey of happiness and purpose. It's about giving yourself permission to be joyous. Join me and unlock your body's natural...

Find Monica:  Website: https://monicasdeepdives.com Twitter: https://twitter.com/monicaperezshow Rokfin: https://rokfin.com/deepdives Rumble: https://rumble.com/user/monicaperezshow YouTube: https://www.youtube.com/c/MonicaPerez  Shownotes: 1) EMA Quality Report - Rapporteurs-Rolling-Review-Report-Quality-COVID-19-mRNA-Vaccine- BioNTec.doc (live.com) 2) SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination: https://onlinelibrary.wiley.com/doi/10.1111/apm.13294 3) Biodistribution of mRNA COVID-19 vaccines in human breast milk https://www.thelancet.com/action/showPdf?pii=S2352-3964%2823%2900366-3 4) FDA - Emergency Use Authorization (EUA) for an Unapproved Product Review Memorandum https://www.fda.gov/media/144416/download 5) EMA Comirnaty Assessment Report - https://www.ema.europa.eu/en/documents/assessment- report/comirnaty-epar-public-assessment-report_en.pdf 6) Three decades of messenger RNA vaccine development - ScienceDirect 7) Frontiers | Are There Hidden Genes in DNA/RNA Vaccines? (frontiersin.org) 8) Effect of mRNA Vaccine Manufacturing Processes on Efficacy and Safety Still an Open Question | The BMJ 9) Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line (nih.gov) 10) dsDNA variance in Pfizer Docs - by Anandamide (substack.com) 11) COVID-19 primary series and booster vaccination and immune imprinting https://www.medrxiv.org/content/10.1101/2022.10.31.22281756v1.full.pdf 12) Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061025 13) A SYSTEMATIC REVIEW OF AUTOPSY FINDINGS IN DEATHS AFTER COVID-19 VACCINATION: https://zenodo.org/record/8120771 14) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine (Cleveland Clinic Study): https://academic.oup.com/ofid/article/10/6/ofad209/7131292?login=false 15) Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents: https://pubmed.ncbi.nlm.nih.gov/36006288/ 16) Deep sequencing of the Moderna and Pfizer bivalent vaccines identifies contamination of expression vectors designed for plasmid amplification in bacteria | Kevin McKernan: https://rumble.com/v2c785k-march-8-2023.html?mref=umbzp&mc=dprv6 17) BNT162b2 Vaccine-Associated Myo/Pericarditis in Adolescents: A Stratified Risk-Benefit Analysis: https://onlinelibrary.wiley.com/doi/10.1111/eci.13759 18) SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents: https://jamanetwork.com/journals/jamacardiology/fullarticle/2791253 19) Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults: https://www.sciencedirect.com/science/article/pii/S0264410X22010283 20) N1 methylpseudouridine is incorporated with higher fdelity than pseudouridine in synthetic RNAs (demonstrates high error rates) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335462/pdf/41598_2022_Article_17249.pdf 22) LNP packaging of dsDNA: https://anandamide.substack.com/p/lnp-packaging-of-dsdna 23) IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222767/ 24) COVID-19 vaccine-associated mortality in the Southern Hemisphere: https://correlation- canada.org/covid-19-vaccine-associated-mortality-in-the-southern-hemisphere/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Find Monica:  Website: https://monicasdeepdives.com Twitter: https://twitter.com/monicaperezshow Rokfin: https://rokfin.com/deepdives Rumble: https://rumble.com/user/monicaperezshow YouTube: https://www.youtube.com/c/MonicaPerez  Shownotes: 1) EMA Quality Report - Rapporteurs-Rolling-Review-Report-Quality-COVID-19-mRNA-Vaccine- BioNTec.doc (live.com) 2) SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination: https://onlinelibrary.wiley.com/doi/10.1111/apm.13294 3) Biodistribution of mRNA COVID-19 vaccines in human breast milk https://www.thelancet.com/action/showPdf?pii=S2352-3964%2823%2900366-3 4) FDA - Emergency Use Authorization (EUA) for an Unapproved Product Review Memorandum https://www.fda.gov/media/144416/download 5) EMA Comirnaty Assessment Report - https://www.ema.europa.eu/en/documents/assessment- report/comirnaty-epar-public-assessment-report_en.pdf 6) Three decades of messenger RNA vaccine development - ScienceDirect 7) Frontiers | Are There Hidden Genes in DNA/RNA Vaccines? (frontiersin.org) 8) Effect of mRNA Vaccine Manufacturing Processes on Efficacy and Safety Still an Open Question | The BMJ 9) Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line (nih.gov) 10) dsDNA variance in Pfizer Docs - by Anandamide (substack.com) 11) COVID-19 primary series and booster vaccination and immune imprinting https://www.medrxiv.org/content/10.1101/2022.10.31.22281756v1.full.pdf 12) Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061025 13) A SYSTEMATIC REVIEW OF AUTOPSY FINDINGS IN DEATHS AFTER COVID-19 VACCINATION: https://zenodo.org/record/8120771 14) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine (Cleveland Clinic Study): https://academic.oup.com/ofid/article/10/6/ofad209/7131292?login=false 15) Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents: https://pubmed.ncbi.nlm.nih.gov/36006288/ 16) Deep sequencing of the Moderna and Pfizer bivalent vaccines identifies contamination of expression vectors designed for plasmid amplification in bacteria | Kevin McKernan: https://rumble.com/v2c785k-march-8-2023.html?mref=umbzp&mc=dprv6 17) BNT162b2 Vaccine-Associated Myo/Pericarditis in Adolescents: A Stratified Risk-Benefit Analysis: https://onlinelibrary.wiley.com/doi/10.1111/eci.13759 18) SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents: https://jamanetwork.com/journals/jamacardiology/fullarticle/2791253 19) Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults: https://www.sciencedirect.com/science/article/pii/S0264410X22010283 20) N1 methylpseudouridine is incorporated with higher fdelity than pseudouridine in synthetic RNAs (demonstrates high error rates) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335462/pdf/41598_2022_Article_17249.pdf 22) LNP packaging of dsDNA: https://anandamide.substack.com/p/lnp-packaging-of-dsdna 23) IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222767/ 24) COVID-19 vaccine-associated mortality in the Southern Hemisphere: https://correlation- canada.org/covid-19-vaccine-associated-mortality-in-the-southern-hemisphere/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Nick talks to Dr. Matthew Hill, a neuroscientist at the University of Calgary whose lab studies how the endocannabinoid system and cannabis (marijuana) influence the brain & behavior. They discuss: endocannabinoid biology; endocannabinoid regulation of stress & anxiety; endocannabinoids & exercise; how marijuana & THC influence brain development; and more.See previous episode with Dr. Matthew Hill: https://mindandmatter.substack.com/p/matthew-hill-endocannabinoid-system-8ff#detailsSupport the showSign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Become a Premium Subscriber to access full content library, including full premium episodes:[https://mindandmatter.substack.com/subscribe?utm_source=menu&simple=true&next=https%3A%2F%2Fmindandmatter.substack.com%2F]Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off:[https://www.lumen.me/shop?fid=8731&utm_source=influencer&utm_medium=influencer&discount=MIND]

Lead Story: The conserved endocannabinoid anandamide modulates olfactory sensitivity to induce hedonic feeding in C. elegans  Current Biology Laboratory worm Caenorhabditis elegans apparently gets the ‘munchies' when exposed to cannabis. After soaking in an endocannabinoid bath, worms preferred to eat nutrient-rich, rather than nutrient-poor, bacteria. They fed for longer than worms not exposed to endocannabinoid or worms without working endocannabinoid receptors. This shared trait points to the deep evolutionary origin of cannabinoid receptors and behaviors influenced by the molecules. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM

https://blog.priceplow.com/podcast/sibyl-swift-lance-blundell-cbdmd-089 On March 27, 2023 we hosted a tremendous conversation with Dr. Sibyl Swift and Lance Blundell of cbdMD, a premier hemp-based health solution company that sells CBD — and even THC — based supplements. In Lance's words, they are a “hemp-extracted cannabinoid company”. Sibyl is cbdMD's Chief Science Officer & VP of Regulatory Affairs, while Lance is the General Counsel at cbdMD. Together, they provide a powerhouse combination of science and regulatory affairs, and in the hemp-based industry, there's plenty to discuss on that front. After getting into their backgrounds, we discuss the ongoing issues between the FDA and CBD supplements, how cbdMD can legally sell THC products online, what CBD can actually do for consumers, and they problems a legitimate company like cbdMD faces in this wild world. This one's a good one, and it won't be our last. As major updates regarding the FDA's regulatory situation with CBD arise, and hemp-based research moves forward, we'll be sure to have them back on. Watch on YouTube below, or listen on your favorite podcast app in our audio feeds: https://www.youtube.com/watch?v=6ZoR0IOZGWc Sybil Swift and Lance Blundell of cbdMD: Detailed Show Notes (0:00) – Introductions – Dr. Sibyl was at the FDA! (5:00) – cbdMD – Who they are and the goals for the company (9:45) – The CBD Market and what's happening within this space (11:50) – Compliance is the hardest complication with CBD & Hemp (16:30) – How should the FDA deal with CBD and Hemp companies like yourself? (20:30) – Partnering with Whoop for a study (22:00) – Sibyl talks about her time working for the FDA (27:45) – What exactly have the FDA said about CBD (33:20) – How does the FDA regulate CBD when it is a much bigger market than supplements (35:00) – Why is it legal for cbdMD to sell THC over the counter like they do? (40:00) – CBD and Delta 8, turning CBD into Delta 8 (42:00) – The ratio of CBD to THC and how it feels when taken as a supplement (44:45) – The difference between cbdMD and other people in the space selling CBD (49:45) – Bringing CBD into the sport and athlete market (53:15) – EnXtra and how it works (58:30) – What claims can be made for CBD/THC etc? (1:05:25) – Claims can't be made due to the FDA's stance on CBD (1:09:20) – Does getting high have anything to do with the safety of the ingredient? (1:11:32) – What are the concerns for safety with people buying CBD? (1:13:28) – How can we help you here at PricePlow and in the Supplement industry in general? (1:16:54) – Have you looked into endocannabinoids and things like Anandamide? (1:19:30) – How do you see the future of CBD and Hemp? Thank you to Dr. Sibyl and Lance for joining us! How to follow Dr. Sybil, Lance, and cbdMD: Dr. Sibyl Swift on LinkedIn Lance Blundell on LinkedIn cbdMD on LinkedIn cbdMD on Instagram You can also sign u... Read more on the PricePlow Blog

Today we are tackling a very important topic - seed oils and their impact on our health. As you probably know, seed oils are also known as vegetable oils, and they're everywhere in processed foods and restaurants.  The top ones to watch out for are soy, safflower, sunflower, corn, cotton seed, canola, grape seed, and rice brown oils. These oils are high in linoleic acid, an omega-six fatty acid that's been linked to the rise in obesity, type two diabetes, heart disease, and non-alcoholic fatty liver disease. Dr. Kate Shanahan, who is one of the first to raise the alarm about the negative impact of these oils, has coined the term "hateful" for these oils. And it's no wonder - these oils are incredibly high in linoleic acid compared to the traditional fats we've been using for thousands of years. In fact, linoleic acid has increased from 9% of our body fat in 1959 to 22% in 2008, which can only come from our diets. The problem with these seed oils is that they're relatively new to our food system, and they've only been around since the introduction of Crisco in 1911. Prior to that, we didn't see much of the diseases that these oils have been linked to. And it's not just the correlation - if you look at the numbers, you'll see that the use of these oils has paralleled the rise in obesity, type two diabetes, and heart disease, while traditional fats like tallow, butter, lard, olive oil, and coconut oil have not shown the same correlation. Hit play to hear this episode of the Healthy AF podcast is all about educating you about the dangers of seed oils and how to make informed choices about what you eat. The information about the correlation between these oils and the rise in diseases is backed up by peer-reviewed studies, and it's something that we all need to be aware of. By choosing to avoid these hateful oils and opting for traditional fats, we can help keep our bodies healthy and strong.   Episode Minute-by-Minute Recap: 0:16 The hateful eight: A short list of seed-oils  1:28 What is Linoleic Acid and why it matters 4:19 When seed-oils first came on the food scene  6:30 The Linoleic Acid concentration in each oil 8:46 Why you need to double-check your avocado oil  13:24 5 Studies everyone needs to know about when it comes to seed oils  21:19 Terms to start searching for to avoid the oils  22:38 How these oils could make us vulnerable to disease  27:44 How long it takes for seed oils to leave your body Connect with Zane:  Join The Healthy AF Club: http://HealthyAF.Club Follow me on Instagram: https://www.instagram.com/zanegriggsfitness ReLyte Electrolytes by Redmond Real Salt https://shop.redmond.life?afmc=Zane   Links For This Episode: See the Charts and Graphs mentioned on this PDF: https://drive.google.com/file/d/1_G0XbEtQDuNOgYZMyOP7mKTbzsftWzmp/view?usp=share_link Dr. Cate Shanahan's blog https://drcate.com/seed-oils/ Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half Century https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4642429/ Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/?fbclid=PAAaaGHjo-VupP3i1wJ4_mfsEXbRHVZdux0OyoiGoXPppgvb6fsmnzjCW-g_U Consumption of a high fat diet rich in omega-6 PUFA for only 4 weeks instigates mitochondrial damage and causes cardiac dysfunction https://pubmed.ncbi.nlm.nih.gov/17023268/ 4-HNE, a byproduct of linoleic acid directly correlates with obesity, growth of visceral fat and insulin resistance. https://pubmed.ncbi.nlm.nih.gov/28088621/ Linoleic acid can cause endothelial dysfunction. More linoleic acid is seen in the LDL of people with type 2 diabetes. https://diabetesjournals.org/diabetes/article/54/5/1506/25939/Linoleic-Acid-Increases-Lectin-Like-Oxidized-LDL#ref-13 The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis https://pubmed.ncbi.nlm.nih.gov/16270280/  

How are attitudes toward cannabis changing? Neil deGrasse Tyson, Chuck Nice, and Gary O'Reilly discuss marijuana's effects on mental health with former football pro turned cannabis professional, Ricky Williams, and Harvard neuroscientist, Dr. Staci Gruber.NOTE: StarTalk+ Patrons can watch or listen to this entire episode commercial-free here: https://startalkmedia.com/show/taking-a-hit-with-dr-staci-gruber-and-ricky-williams/Photo Credit: United States Fish and Wildlife Service, Public domain, via Wikimedia Commons

The Endocannabinoid System If you'd like to keep up with everything else we do please visit https://strangeapothecary.co.uk Join our community - https://www.facebook.com/groups/strangeapothecary What is The Endocannabinoid System? The Endocannabinoid System (or ECS for short) is a complex cell-signalling system in the body that is responsible for maintaining homeostasis (balance) in virtually every system in the body. The ECS was identified in 1992 by Professor Raphael Mechoulam and his researchers who were exploring exactly how the Cannabinoid, THC, works in the body. The Endocannabinoid System plays a role in your body's functions such as sleep, mood, appetite, memory, reproduction & fertility. There are three main parts to our Endocannabinoid System (ECS): Endocannabinoid molecules Cannabinoid receptors Enzymes Endocannabinoids are molecules made by your body. The 2 known Endocannabinoids are 2-AG & Anandamide. These help keep the body's internal functions running smoothly. Your body produces them as needed so it's hard to keep track if there's a deficiency. The Cannabinoid receptors around our body are called CB1 & CB2. CB1 receptors are mostly found in the central nervous system. CB2 receptors are mostly found in your peripheral nervous system, especially immune cells. Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to. There are two main enzymes: fatty acid amide hydrolase monoacylglycerol acid lipase These are responsible for creating endocannabinoids, transporting them to our receptors and breaking down endocannabinoids once they have performed their function. Research has linked the ECS to the following processes: Appetite and digestion Metabolism Chronic pain Inflammation Mood Learning and memory Motor control Sleep Cardiovascular system function Muscle formation Bone remodelling and growth Liver function Stress Reproductive system function Skin and nerve function Ways to give your Endocannabinoid System a boost. Take a Cannabinoid supplement like CBD. Try aerobic exercise. Add Cacao & Maca roots to your diet. Look for other herbs with Cannabinoid properties. Supplement omega-3. The Endocannabinoid System is still significantly underestimated and is still being researched today. We highly recommend you do some extra research because we haven't even scratched the surface in this video, This is just basic knowledge to help get you started. Thanks for joining us on today's episode, we hope you learned something new. Please like, subscribe & ding the bell so you don't miss future uploads. Sources: CBD E-Book by Hannabis - https://strangeapothecary.co.uk/product/free-cbd-ebook/ The CBD Bible by Dr Dani Gordon - https://amzn.to/3PEXZGG The Rebel's Apothecary by Jenny Sansouci - https://amzn.to/3PoCSsE

The discussion over what aspect of our diet has been driving the escalation of metabolic disease over the last 100 years has been a confusing one full of contradictory information. It would be logical to look for a change in our diet associated with such a dramatic change in the health of a population There are both correlated evidence and dietary trials to support the theory that the increase in linoleic acid, provided by the introduction of PUFA processed oils into our diet, is the driver. In this episode of Hunger Hunt Feast, I want to share a collection of them to help clarify some of the confusion. -- Episode Specific Links:  Linoleic acid concentrations in fats and oils http://www.distributionkatrina.com/english/comparison-of-dietary-fats.html Increase in Adipose Tissue Linoleic Acid of US Adults in the Last Half-Century https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4642429/ Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla https://www.sciencedirect.com/science/article/pii/S0022227520346733 Diets could prevent many diseases https://www.researchgate.net/publication/10673140_Diets_could_prevent_many_diseases Corn Oil in Treatment of Ischemic Heart Disease https://ncbi.nlm.nih.gov/pmc/articles/PMC2166702/ Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse https://pubmed.ncbi.nlm.nih.gov/27886622/#:~:text=the%20male%20mouse-,Linoleic%20acid%20causes%20greater%20weight%20gain%20than%20saturated%20fat%20without,doi%3A%2010.1016%2Fj Effects of fatty acids on mitochondria: implications for cell death https://pubmed.ncbi.nlm.nih.gov/12206909/ Can linoleic acid contribute to coronary artery disease? https://pubmed.ncbi.nlm.nih.gov/8192728/ Effects of linoleate-enriched and oleate-enriched diets in combination with alpha-tocopherol on the susceptibility of LDL and LDL subfractions to oxidative modification in humans https://pubmed.ncbi.nlm.nih.gov/8148354/ Acrolein is a product of lipid peroxidation reaction https://www.jbc.org/article/S0021-9258(18)80708-6/fulltext#seccestitle90 The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis https://pubmed.ncbi.nlm.nih.gov/16270280/ Rapeseed oil and sunflower oil diets enhance platelet in vitro aggregation and thromboxane production in healthy men when compared with milk fat or habitual diets https://pubmed.ncbi.nlm.nih.gov/1641826/ Stearoyl-CoA Desaturase-1 Is Associated with Insulin Resistance in Morbidly Obese Subjects https://link.springer.com/article/10.2119/molmed.2010.00078 Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/ Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/ Role of Physiological Levels of 4-Hydroxynonenal on Adipocyte Biology: Implications for Obesity and Metabolic Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038367/ “The Hateful Eight: Enemy Fats That Destroy Your Health - Dr. Cate.” Dr. Cate, 22 May 2020,  https://drcate.com/the-hateful-eight-enemy-fats-that-destroy-your-health/ Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6180905/ Strong increase in hydroxy fatty acids derived from linoleic acid in human low-density lipoproteins of atherosclerotic patients https://pubmed.ncbi.nlm.nih.gov/9488997/ Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA https://journals.physiology.org/doi/full/10.1152/ajpheart.00480.2004?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org Changes in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a) https://pubmed.ncbi.nlm.nih.gov/9844997/ “Dr. Knobbe Presents, ‘Macular Degeneration - Preventable & Treatable - With an Ancestral Diet?' at Weston A. Price Foundation's Annual Conference - Wise Traditions - 2017 - Cure AMD Foundation.” Cure AMD Foundation, https://www.cureamd.org/dr-knobbe-presents-macular-degeneration-preventable-treatable-with-an-ancestral-diet-at-weston-a-price-foundations-annual-conference-wise-traditions-2017/ Unsaturated fatty acids and their oxidation products stimulate CD36 expression in human macrophages https://www.researchgate.net/publication/11260045_Unsaturated_fatty_acids_and_their_oxidation_products_stimulate_CD36_expression_in_human_macrophages Lowering dietary linoleic acid (LA) reduces bioactive oxidized linoleic acid metabolites in humans https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3467319/ Can linoleic acid contribute to coronary artery disease? https://www.researchgate.net/publication/15005994_Can_linoleic_acid_contribute_to_coronary_artery_disease A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://pubmed.ncbi.nlm.nih.gov/9844997/ Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2012.38 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis https://www.bmj.com/content/346/bmj.e8707 Connect with Zane: ReLyte Electrolytes by Redmond Real Salt: https://shop.redmond.life?afmc=Zane Follow me on Instagram: https://www.instagram.com/zanegriggsfitness Follow me on YouTube: https://www.youtube.com/c/ZaneGriggs QUICK EPISODE SUMMARY What causes modern disease The hateful eight oils The correlation between vegetable oils and obesity The oxidation effects of LDL The truth about the dairy data How much cholesterol is in your brain  Where you can find a copy of today's mentioned study What we know about Linoleic acid

What is Flow? The optimal state of consciousness where human beings perform and feel at their very best. It's a form of energy. I invite you to recall a time when you were so immersed in something you completely lost track of time. Have you noticed when you have been in a state where life's distractions did not bother you or you skipped a meal and didn't even feel hungry or notice it?  Have you been so connected with someone where you were in deep listening and collaboration with hours going by without noticing?  Have you observed your child sit for hours paying video games?Why is this?  There is an opportunity to discipline our unconscious mind by focusing on and even generate thoughts of our own choosing and attach meaning to them at the unconscious level to influence our behavior.  We can create internal representations of events that empower and engage us to create our own reality. Thoughts and Internal representations trigger our emotions and perceptions. This can cause us to allow our thinking to just sort of happen to us. However, we do have the power to control our thinking, lives, behavior, and results.  We open up a new dimension of our thinking and a higher version of ourselves.How can we enter the flow state?It's been scientifically proven to enter the flow state at will whenever you want. Having the attitude is the first step.  It's all about the journey! Essential Elements of the Flow state:Train yourself to experience the flow state at will, operate at flow including mundane tasks or those you may not have enjoyed in the past. ·       Setting a goal that does not risk becoming overwhelming or boring. ·       Breaking goals down to create smaller achievable goals that can be internalized.·       Focus attention on that goal. One at a time.·       Take concentrated action to achieving that goal. (block out distractions) ·       Time will disappear in the flow state·       Get better and better at the things in your life and when you achieve, challenge yourself with the next level.·       Be fully involved in the process.Chaos and Flow:Can you recall a time when you didn't have anywhere to be, clean to-do list, nobody tapping you for something? Once the initial feeling of this freedom passes, entropy brings in chaos. It brings in thoughts from the past (ruminate over) or into the future (worry). Our default setting is peace/calm/happiness, but the system and programming we have been exposed to creates the habitual mind. Chaos and disorder tend to be the operation.   Basically, as soon as we feel like we are ‘happy' we tend to challenge it and quickly shift into chaos. Chaos can exist in perceived order and order can exist in chaos. Typically, we are externally focused to find solutions to get to happiness. Instead, creating rewards within themselves and learning to enjoy the process of whatever it is they are doing can help them create order and get them into a state of flow. Science of Flow:Have you ever heard about the state of a runner's high, getting in the zone (athletes), musicians getting their groove. It's more common than you might think!  You can go in and out of multiple instances of the flow state. Flow is actually in our brains. Marked by a cascade of positive chemicals the brain releases in a way in which we perceive the task internally.  For instance. Mopping the floor sounds boring and mundane, but adding some fun to it can change the internal representation of mopping the floor. How about the process by changing up how you do it so the floor dries faster or inventing a machine in your mind that does the job while pretending to be that machine. Make it fun and challenging in a good way! As chemicals disburse around the body it changes our physiology.  There is still work to be done.One of the inspirations for this episode is helping others to find their flow. It's not easy with so many distractions and overwhelm throughout the day. Our energy can be sporadic and if we depend on caffeine for our energy that can take us up as fast as it can down. It's been important to me to find something that not only helps me find creativity WHEN I need to, but to help me get into flow. Focus and clarity are key here.  I started drinking these green shots from Magicmind and I love them! They help me so much every morning and I can get into flow. I usually drink them alongside my morning coffee.   Ancient teachings tell us that stress is the body's inability to predict what's coming next, taking the mind out of ‘homeostasis' (the self-preservation state). A disciplined mind, combined with the tools that help it be disciplined (nootropics, adaptogens) leads to getting more stuff done in less time and eventually to a disciplined and stress-free life.  Seeing how well it worked for me, l really encourage you to try it out as well if you're having trouble tapping into your creativity, focus and finding clarity in your day. It's a total game changer.  I have a 20% off code to share with you guys, it's SHIFTING20. To use it, you can go to magicmind.co/shifting and enter the code SHIFTING20 at checkout. The best part is that they have a money back guarantee. If you get a subscription, you can get 40% off using SHIFTING20 (for the next 10 days). Stages of Flow: How to create a state of flow consistently and at will.Struggle – you are learning about the thing you want to get good at. Conscious brain is fully engaged at this stage. Conscious incompetent stage. The planning portion, animal impulses, identity. For instance, Writing a book it's the interviews stage. Learning to play guitar, observing what it is you need to learn. This is trying to figure out what it is we need to learn to accomplish our goal or solve the problem. Relaxation – Consciously stop whatever you are doing completely to give your brain a rest. Slow down breathing. Take a nap, light swimming or yoga. Walk, gardening help to clear the mind and allow it to reboot. This is not TV or another activity that keeps your brain in activity. Start to use our intuition and use new ideas to do things.  Flow state - The Body is flooded with feel good chemicals. It releases dopamine helps us to enhance our focus, take in more info per second than we normally can). Our unconscious releases Anandamide speeds up lateral thinking which helps us to link up ideas and triggers new ideas and inspiration. Endorphins and serotonin which calms us to feel good about the process. Conscious and unconscious minds are working together in harmony. Problems are easily solved even if you were struggling with them before. Getting form point A to B becomes simple and automatic without concentration.  Prefrontal cortex shuts down. Time often either expands/contracts for us during this phase. Self-critic area of the brain shuts down and Creativity and risk taking goes up. Full engagement with unconscious mind. Enhanced performance while using little energy. Alpha or even Theta waves are accessed in the brain.Recovery – Conscious and unconscious minds consolidate what has been learned. Dealing with chemical changes in the body feeling drained or down. While this is a normal part of the process you can stay on par allowing for you to access Accelerated learning.How to get into Flow state?·       Create Games/mini-tasks - Take tasks you don't necessarily like to do and ask yourself how you can make it more efficient, more fun, do it faster, do away without ever having to do the task again, invent a machine to do the task for me.  I love music helping me to get into flow. Paramore has been my flow music lately.  I choose something that pairs nicely with the task and getting into flow.·       How to disengage and clear your mind. The first thing you do is instruct your conscious mind to consider everything you are about to say. And then either out loud or in your mind while focus on pupils in mirror and say: Everything and nothing, everywhere and nowhere. Pause. Say it again. Pause.·       Do things you love just because you love it and want to do it, for no other reason.·       Practice gratitude every day – for the times you experience flow and all the other good things you enjoy.Triggers for flow (pick something that works for you) based on a combination of interviews with athletes in the zone and brain imaging techniques to scientifically confirm the subjective descriptions of that particular state. Steven Kotler has studied and come up with 17 triggers. The more intense the triggers the more momentum to get into/stay in Flow.4 physiological triggers: (individual)·       Deep concentration for long periods of time (no multi-tasking) – solitude typical, be in present moment·       Have clear goals – SMART Goals to engage with unconscious mind·       Immediate feedback lets you know if you're on the right track of your goal (allows you to be in the present moment – keeping in flow)·       Set a challenge that is slightly more difficult than your current skill level  (not too high or anxiety can slip you out of flow, too low creates boredom and slip out of flow) – find a balance between challenge and skill.3 Environmental triggers (individual)·       High consequences – when stakes are high, we don't need to force ourselves to concentrate. We do this naturally.·       Introduce a rich environment - unpredictability, complexity, and anything can happen. Lots of information comes in.·       Deep embodiment – Must be intensely focused with a full immersion strategy – comes in bursts. downhill skier.9 social triggers – can put a group into flow state. ·       Good communication – disciplined about what is/isn't allowed·       Naysaying not allowed·       Similar skills/roles ·       Equal responsibility ·       Aligned intentions·       Inclusion of everyone on team – each person equally important·       Element of Risk – Always going to be potential for failure. Flow doesn't happen with some sense of risk.·       Active listening – fully engaged in convo (each group member) - focused in the moment.·       Avoid negativity and arguments (blocks momentum, breaks flow state. Goal is to build momentum by amplifying each other's ideas.1 creative trigger·       Creativity – individual and group. Creativity triggers flow and flow enhances creativity. Linking ideas together to form new ideas. Flow in everyday life:Can initiate in many different contexts and many different situations. Stretch yourself when you have opportunities to get into the state of flow and maintaining it. Give yourself a mini challenge. Results of Flow:Here are just some results of flow: Improved health, creations (art, music, etc.), forget about physical pain temporarily, increased creativity, improved self-esteem, linked to higher levels of happiness. Being able to tap into the fullest expression of self. Happiness is a decision. More to do with mindset than external circumstances. If you want to continue building this technique and want to dive deeper I'm taking applications for Living Purpose-FULL 6-month group coaching program!  Move from burnt out and stuck to thriving! Month 5 is actually called Ebb & Flow where we tackle some of the blocks to get into flow. Learn more at www.angiemccourt.com/group-coaching. These next 10 days, you can get 40% off your Magic Mind subscription at: https://www.magicmind.co/shifting With My Discount Code: SHIFTING20

Jeff is.........bringing bliss to South Florida. Born in Miami, and raised in Fort Lauderdale area, he went to UF Gainesville for an undergrad degree in business, entrepreneurship, and real estate, before studying law and working at a startup in the area. When that project failed, he went out to San Francisco to work for Google, traveled the world for 9 months working remotely, and when COVID hit he was in New York, dealing with the lows, before making the decision last November to move to Miami, like so many others. After taking a handstand class in Bali, and learning acro yoga in NYC, he discovered an opportunity in Miami, to go stay on a Cacao farm in Nicaragua for 6 weeks. There he discovered ecstatic dance, the power of vasodilators, and met his girlfriend, coming back to Miami a changed man with a new connection to sustainably sourced cacao. Together they started their company, Cacao Sol, first selling at the farmers market in Coconut Grove, and now have plans for their very own store, in addition to providing cacao for all kinds of enlightened events here in Miami. Never tried raw cacao or experienced a ceremony? Follow @jeffmoves and @cacao.sol on Instagram, and open yourself to the power of Anandamide, the bliss molecule.

The active ingredient in marijuana is delta-0-tetrahydrocannabinol (THC). THC mimics the action of the natural neurotransmitter N-arachidonoyl ethanolamide (anandamide). Anandamide binds to CB1 cannabinoid receptors throughout the brain and CB2 receptors in the body. CB2 receptors have a role in regulating immune function. CB1 receptors impacts mood, memory, appetite, pain, and cognition. --- Support this podcast: https://anchor.fm/richard-hindmarsh0/support

Nick talks to Saoirse O'Sullivan, PhD, a physiologist specializing in the physiological effects of cannabinoids. Dr. O'Sullivan ran a lab at the University of Nottingham for many years before becoming a consultant and Vice President of Translational Research at Artello Biosciences. Nick and Saoirse discussed some of the physiological effects of cannabinoids in the body, including endogenous cannabinoids that our own bodies produce, and plant cannabinoids associated with the Cannabis plant (e.g. THC, CBD, THCV, and CBG). They cover a number areas of physiology and systems in the body, including inflammation, brain injury, the blood-brain barrier, gut health, and the cardiovascular system. Towards the end, Saoirse also described why she eventually made the transition from academia to the private sector, and motivated her decision to do so despite having been a successful researcher and being granted tenure as a professor.USEFUL LINKS:Download the podcast & follow Nick at his website[www.nickjikomes.com]Support the show on Patreon & get early access to episodes[https://www.patreon.com/nickjikomes]Sign up for the weekly Mind & Matter newsletter[https://mindandmatter.substack.com/]Athletic Greens, comprehensive daily nutrition (Free 1-year supply of Vitamin D w/ purchase)[https://www.athleticgreens.com/mindandmatter]Try MUD/WTR, a mushroom-based coffee alternative[https://www.mudwtr.com/mindmatter]Discount Code ($5 off) = MINDMATTEROrganize your digital highlights & notes w/ Readwise (2 months free w/ subscription)[https://readwise.io/nickjikomes/]Start your own podcast (get $20 Amazon gift card after signup)[https://www.buzzsprout.com/?referrer_id=1507198]Buy Mind & Matter T-Shirts[https://www.etsy.com/shop/OURMIND?ref=simple-shop-header-name&listing_id=1036758072§ion_id=34648633]Connect with Nick Jikomes on Twitter[https://twitter.com/trikomes]​​​Learn more about our podcast sponsor, Dosist[https://dosist.com/]ABOUT Nick Jikomes:Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, a technology startup in the legal cannabis industry. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.Support the show (https://www.patreon.com/nickjikomes)

In this last gab of the sesh, Christine Stio and I go deeply personal and find cannabis truth in every topic from how it feels when science tickles our fancy to the real world problems of single mothers in the city. You won't be disappointed in the juicy stuff you learn from being a fly on the wall in this conversation. She names names and I'm leaving contact info down below. The power of love is working here. Oh that may sound a little sappy for some of you… but really, feeling loved is so important to one's mental health and emotional health. We all know that, So enjoy this bundle of love comin atcha and as Cinderella used to say, Have Courage and Be Kind. She also wants you to have the advantage of some great links to science information but more than that, she give us links to some leaders in calming your mind and heart. Like Dr. Brian Wise, author of Same Soul, Many Bodies. And it's very important to know a good cannabis attorney like Jacob Zagland in the NY area and Michael Doyle, her cannabis consultant for her brand new start up called Buzzadoo's Canna Delivery Service, named by her son! When discussing how to communicate, she mentioned two more interesting speakers; Mark Eden and Loretta J. Ross who said, “Don't call people OUT! Call them in…” And in today's climate of devision, I really want to learn how to communicate effectively. It's a great series gab between two mothers… and two Women in Weed. Come join us! I met this Woman in Weed through the LinkedIn Platform… she'd found my podcast and heard Dr. Leah Johnson and the rest is history. We have so much in common and her story is so typical of struggling entrepreneurial mothers. But this ganja mama is leading her state. Wait till you hear our continued gab about her autistic son, Aiden, the joy he provides, and the work they're doing to help others. Also mentioned on the show is Healer.com for Dr. Dustin Sulak's new bible for physicians called: Handbook of Cannabis for Clinicians - Practices and Procedures, which can be found on Amazon.com. Imagine being a teacher, business owner, single mother of a great 16 year old autistic son and about to become one of the first Cannabis Delivery Companies in NY state… Now let's see how this super mom does it and what brought her from the traditional School System to this advanced idea! Another amazingly creative Woman in Weed who reminds us of the hardship of first world problems;) She also wants you to have the advantage of some great links to science information but more than that, she give us links to some leaders in calming your mind and heart. Like Dr. Brian Weiss, author of Same Soul, Many Bodies. And it's very important to know a good cannabis attorney like Jacob Zoghlin in the NY area and Michael Doyle and Chris Massaad, her cannabis consultants for her brand new start up called Buzzadoo's Canna Delivery Service, named by her son! When discussing how to communicate, she mentioned two more interesting speakers; Mark Eden who posted about TedTalker Loretta J. Ross who said, “Don't call people OUT! Call them in…” And in today's Climate of Division, I really want to learn how to communicate effectively. It's a great series gab between two Women in Weed. Come join us! Oh one more thing… Find Christine Stio on LinkedIn, as cannabisqueenchristine on Instagram, and her email is: nannyjordan04@yahoo.com --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/cannabaverum/support

Tucker Goodrich is a technology executive in the financial industry who designs, runs, and debugs complex systems in high-risk environments. Areas of expertise include risk management, systems management, and cyber-security. After experiencing some personal health crises and realizing that the ‘solutions' offered by medical professionals weren't working or addressing causation he started applying the same approach in research and evaluation of data to his own health issues to determine root causes. His interests have focused on dietary and environmental drivers of chronic disease, including carbohydrate, wheat, and various classes of fats. Specifically, he's attempting to understand and popularize understanding of the mechanisms driving the diet-derived explosion in so-called chronic diseases (or diseases of civilization). He is active on twitter (@tuckergoodrich, has a blog called Yelling Stop, is an Expert Advisor for the nutrition start-up Nutrita, and has been a guest on numerous podcasts.   Time Stamps: 0:10:16 Podcast begins 0:12:16 Tucker's blog post: https://yelling-stop.blogspot.com/2021/06/thoughts-on-of-rats-and-sidney-diet.html 0:14:16 Compounds that reduce overeating 0:17:16 Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity: https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2012.38 0:23:31 Endocannabinoid signal in the gut controls dietary fat intake: https://www.pnas.org/content/108/31/12904 0:29:56 A Neural Circuit for Gut-Induced Reward: https://www.cell.com/cell/fulltext/S0092-8674(18)31110-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867418311103%3Fshowall%3Dtrue 0:35:46 CRP is a marker of oxidized linoleic acid 0:38:32 Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials: https://pubs.rsc.org/en/content/articlelanding/2017/FO/C7FO00433H 0:43:06 Take a pill or just stop eating so many seed oils? 0:45:16 Low‐Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events: https://www.ahajournals.org/doi/10.1161/JAHA.119.016318 0:49:46 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans: https://pubmed.ncbi.nlm.nih.gov/9844997/ 0:54:16 HNE - what is it and why is it important? 0:58:36 Where is linoleic acid even found? 1:02:46 The average amount of linoleic acid in the human diet 1:12:06 Why I don't eat bacon 1:14:46 Just because a study was conducted a long time ago, doesn't mean it should be ruled out 1:20:31 Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73): https://www.bmj.com/content/353/bmj.i1246 1:27:16 When low LDL can result in a higher risk of cardiovascular disease 1:28:31 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis: https://www.bmj.com/content/346/bmj.e8707 1:32:16 Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study: https://pubmed.ncbi.nlm.nih.gov/9989963/ 1:40:40 The blood test you should consider getting  1:42:55 The idea of "intralipid" 1:51:00 Tucker's personal experience with weight loss and dietary changes 2:03:10 Health Characteristics of the Wayuu Indigenous People: https://academic.oup.com/milmed/article/184/7-8/e371/5481850 2:07:25 Where to find more of Tucker Goodrich   Sponsors: Blazing Bull: $150 off of a 1500 degree grill at BlazingBullGrills.com with code “CARNIVOREMD” at checkout Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd  White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order Belcampo: www.belcampo.com use code: CarnivoreMD for 20% off your order

(Part 2) Dr. Daniele Piomelli reveals a deeper understanding of our Endocannabinoid System (ECS). A system so critical to our ability to thrive, it’s surprising it was only discovered about 30 years ago, mostly thanks to cannabis. However we don’t actually need our ECS to survive, so what is its purpose? And could we have evolved to cooperate in large groups without it?   P.S. World’s best search engine for Video Cannabis Education = PeriodicSearch.com Send a message with the “Contact Us” Button on PeriodicSearch.com homepage. Schedule 1-on-1 call w/ Wayne (Office Hours, Fri 2-4pm PST) *read details for 1-on-1 calls in this calendar link

What are Anandamide and 2AG? Misconceptions about euphoric highs and endorphins, ECS science, sleep deprivation and stress, you're breathing wrong! Check out Dr Todd's website at www.DrStevenTodd.com --- Send in a voice message: https://anchor.fm/the-fitness-zone-podcast/message

In this episode I talk about Anandamide, which is a neurotransmitter which has close links with happiness in human beings. Listen to learn more. The Opulent Guy ©

In this episode, we get back to one of the most popular topics on Woke & Wired and cover all things ceremonial cacao with Keith Wilson of Keith’s Cacao. Use discount code BREAKFASTCRIMINALS when you order ceremonial cacao on keithscacao.com. We discuss:  What is ceremonial cacao?  What is a cacao ceremony?  Cacao as a food of the shift  How Keith sources cacao with guidance from the Cacao Spirit  Cacao as a driver for creativity and innovation  Why how you drink cacao is not as important as the cacao you drink  Caffeine in chocolate VS caffeine in ceremonial cacao  Plant medicines critical to the formation of civilization and why cacao might be one of them!  Anandamide (“bliss” molecule in cacao) Naturally occurring endocannabinoids in cacao Psychedelic medicines and cacao The unexpected result from combining cacao and DMT Why hand peeling cacao makes a big difference  How ceremonial grade cacao is made How cacao guided Keith Wilson to become an entrepreneur  Co-creating business with Spirit  Keith shares his intuitive message for me and the listeners! See all show notes and more episodes on wokeandwired.com Connect with Keith:  Keithscacao.com – use code BREAKFASTCRIMINALS for 5% off ceremonialcacao.blogspot.com youtube.com/keithscacao Keith’s Cacao Recipe Mentioned by Ksenia:  At Home with Ksenia on YouTube The Cacao Portal  Woke & Wired episode 14 – cacao and Maya cosmovision Woke & Wired episode 101 – cacao and frequency healing Share your medicine with the world meditation on Insight Timer Mentioned by Keith:  Mayanutinstitute.org Alison Coe on YouTube  Connect with Woke & Wired: If you enjoyed the podcast, share it with a friend or on Instagram stories (tag @wokeandwired). Subscribe, rate and review the show on iTunes. Experience alignment with the 5-Day Social Media Challenge. Join my email list to know about upcoming workshops and more.

Season 4 kicks off without the long intro: This about getting to the talk immediately! Its an episode taking an amazing dive into a subject that is going to create a double-take for some people. I'm joined today my Michelle Ching, whom I met on Instagram where she was discussing the Endocannabinoid system with another podcaster. It's one of my favourite topics to discuss in terms of the wisdom of the body and the capabilities our cells have to regulate us in trauma and threat responses and flow! Its a widely misunderstood system and one that often gets a bad wrap when you discover that its the same biological process associated with CBD, and THC. If you don't know what these are? Then listen in!! Hint this is not a chat about cannabis. Firstly we begin with a look at the western medical system and why we both now work, speak and exist in the world of holistic and co-operative healthcare, from there 00:05 We begin! 06:00 Mental health and coaching, self and purpose. 09:00 Wonderfull products and why they are CBD based 12:00 Endogenous cannabinoid systems and how these work with CBD 18:00 Safety and threat 27:00 Mitochondria and Endocannabinoid systems 33:00 Anandamide- an amazing molecule 41:00 Physician/Therapist overseeing, why we really need someone to watch and care along with us. 50:00 The ECS - an extraordinary system. 58:00 Cannabis and "insert named disease", what's the connection? 1 hour onwards : side effects, delivery methods, dosages Trauma-informed holistic healing and an ECS approach

When you get out into “the wild” (I love to do a one hour nature walk at the end of my work day but the wilderness for you could be a quiet room in your home or running through your neighborhood), your brain waves slow down from beta to alpha.When this happens–amid solitude–the part of your brain responsible for self-criticism, mental chatter and constant worry shuts down. This silencing of the prefrontal cortex happens temporarily and is known to neuroscientists as Transient Hypofrontality.With the prefrontal cortex temporarily quiet and your monkey mind on a little vacation, you enter the Flow State. Elite athletes know this as “the zone” and it’s the place where all great performance begins. In Flow, your neurochemistry is altered. Dopamine (the neurochemical of inspiration) gets released. Anandamide (the neurochemical of bliss) shows up. And serotonin (the neurochemical of pleasure) kicks in.With what I call “A Pharmacy for Mastery” in place, you get your best ideas. Your creativity makes explosive gains. You begin to see around corners. And solve problems that few humans ever get to solve.

Have you been wondering what the buzz around CBD is all about? What is Hemp? Is it safe? Can it help us? Our guest today is the founder of Hemp & Humanity, Melissa Gibson. There is so much misinformation floating around about CBD today, Melissa is here to share with us some facts about it. CBD, short for Cannabidiol, is one of over 100 naturally occurring compounds that can be found in the hemp plant. Hemp is one variety of the cannabis plant that is distinguished by its lack of THC; by definition, hemp has less than three-tenths of one percent (.3%) of THC. While THC is the molecule responsible for feelings of euphoria, CBD does not have an intoxicating effect and cannot get you high. CBD is known as a phytocannabinoid, meaning it’s a cannabinoid that comes from plants. Our body generates its own type of cannabinoids, called endocannabinoids (endo meaning ‘within’) -- the most prominent are 2AG and Anandamide. Melissa talks a bit about what Social Enterprise is and why she was so drawn to it. She’s pulled towards sustainability because she spent years in a space where Social Enterprise was the focus. It meant she could do business and reflect a concern for the community in which she lived. She’s excited for the next generation of women coming through the Social Enterprise space. Now with new technologies, it’s possible to take things you’re passionate about and combine them with what you want to do professionally. If you’re just starting out, look out for the new educational programs springing up around the country!  Melissa then walks us through an obstacle she faced and how she overcame it. When she first started her business, the plant itself wasn’t federally legal, but thanks to a gray area, she was able to keep up with the industry. To do that, her business educates and sells curated CBD products. Unfortunately, she wasn’t able to use credit or debit-card purchasing. This made it incredibly hard to scale and grow. This forced her to rethink her business and take it to the people. She needed to be face to face with a customer where she could educate them and exchange cash. She got involved with local farmer’s markets and spoke with hundreds of people. She was able to give as much information as possible to empower that individual to make the choice for themselves.  CBD has enabled Melissa to get relief from her multiple immune disorders, recover from athletic training, decrease arthritis pain, reduce anxiety. and maintain balance. In October of 2017, after a year of regular use of the most highly effective CBD products, Melissa’s endocrinologist delivered the news that her Graves Diseases is headed toward remission. She feels the best she has in years and enjoys helping others to optimize their own health and wellbeing. Some define good health simply to be: physiological homeostasis. Remember homeostasis from Science class? We learned about it in terms of body temperature and thermogenesis – one example of homeostasis. When we’re too cold, we shiver to warm up. When we’re too hot, we sweat to cool off. Basically, homeostasis refers to a dynamic system of balance and maintenance in our bodies. The main function of cannabinoids, whether they are endocannabinoids like 2AG and Anandamide, or phytocannabinoids like CBD, is to help create homeostasis. This is accomplished by engagement with what is called, The Endocannabinoid System (ECS), the “Master Regulator” of other systems in our body. It is vital that our ECS is nourished, and CBD has been found to be an effective agent in this process. What you’ll learn On today’s episode, Melissa clears up what exactly CBD is, how it can help us, and why it’s important to educate our society about it. She also dives into how she got into this industry and Social Enterprise.    LINKS https://hempandhumanity.com/ melissa@hempandhumanity.com - Complimentary consultation for Listeners!

I'm so excited about today's guest: She's very unique in that She calls herself an Evolution Junkie! She is a copywriter and host of Onconscious Podcast. She's all about conscious Evolution, Abundance and Transformation.  Hailing from Singapore, She currently resides in Dubai, UAE and consider's herself a global citizen. If she's not pursuing Anandamide on her Kawasaki Cafe Racer, she is usually creating, or soaking up information on ways to develop more Focus, Awareness & Presence in our everyday lives so that she can better impact the world. Join Reva and her Co-Host Chris McLean for weekly explorations of the latest techniques, strategies & adventures in peak performance, biohacking, flow states, mindfulness & living onconscious. How To Get OnConscious… 1. You take 25,000 breaths a day. Be aware. Breathe. 2. Notice your thoughts. Don't judge. Kill negativity. 3. Change your mindset with movement. Get off your ass. 4. Forget tradition. Forgo routine. Try different. 5. Need a challenge? Pick one from our podcasts. Run with it.   http://onconsciouspodcast.com/about/ Learn more about your ad choices. Visit megaphone.fm/adchoices

If you work in the cannabis business, you've probably heard of the endocannabinoid system, you might even talk about it in your marketing materials to explain why customers should buy your products. The sad truth is though, for the vast majority of the population, doctors included, the endocannabinoid system isn't even on their radar.If you're listening today, you may have a cursory knowledge of how the endocannabinoid system works, but even the scientific researchers we so admire would admit much still remains to be learned about its significance to our health and wellbeing. So for any of the endocannabinoid-curious amongst us, this podcast with neuroscientist Dr Greg Gerdeman is essential listening. Greg has been involved with many key discoveries regarding the ECS and for many years taught marine biology college students at Eckerd College in Florida about the ECS and neurobiology. So if like me, you never made it past high school science classes, listening to Greg share his knowledge about the endocannabinoid system, human biology and our evolution as a species is a real privilege normally reserved for undergrad students. Resources:Feeling Corona-Crazy? Give your endocannabinoid system a boost My article for Project CBD featuring Dr Gerdeman's interviewWired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the ‘runner’s high’ (Journal of Experimental Biology, Greg Gerdeman et al)An Analysis of Endocannabinoid Concentrations and Mood Following Singing and Exercise in Healthy Volunteers (Frontiers in Behavioural Neuroscience, Saoirse O'Sullivan et al) The endocannabinoid system and the biology of wellness (video with Greg Gerdeman and Martin A. Lee for Project CBD)Support the show (https://www.paypal.com/paypalme/marybiles71)

We are living in unprecedented stressful times with levels of uncertainty never experienced in our life times. It's vital we find ways to manage our stress so that it doesn't turn into its close cousins depression and anxiety. That's why today I've chatted to Dr Julie Moltke, a medical doctor with a special interest in stress management, mental health and cannabis medicine.Dr Julie explains in very clear turns how stress affects our bodies and minds - but also describes how we can consciously use techniques such as mindfulness and meditation to calm our nervous systems.Of course, being Cannabis Voices, we discuss how cannabis (and CBD) can help lessen stress and anxiety, through its interaction with the endocannabinoid system.And as a special treat for listeners who make it to the end of the podcast, Dr Julie gives a very relaxing guided meditation, bringing us into the present moment and a state of calm tranquility. Enjoy!ResourcesA Quick Guide To CBD by Dr Julie MoltkeClinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes by Dr Ethan Russo5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in ratsHeadspace - A meditation app that is a great way to start a meditation practice Support the show (https://www.paypal.com/paypalme/marybiles71)

Eric Rieger  Alright, we're going to get down to the gut check project starting on episode 34. It's gonna be a quick one, but you're gonna love it.Ken Brown  Yeah, we're gonna try and do this a little bit quicker because what I've gotten some feedback is when you guys get all sciency that sometimes it's it's cool to hear the fun stuff, but the reality is that the science gets a little geeky and it gets almost like a lecture. So I apologize to everyone out there if I've been some weird professor but so my only thing so let's do the personal stuff is your family good? Eric Rieger  Family's Great! Awesome. Ken Brown  My family's great also awesome. And that's up for the personal stuff. So like I said, I was called by a good friend, Tim, our good friend his father had... Eric Rieger  Tim Power been on the show. Ken Brown  Yeah, Tim power been on the show. His father had a stroke. And he messaged me and he said, Hey, man, my dad had a stroke, and they don't seem to be talking diet. They don't seem to talking supplements. He's in rehab. He's getting better. I'm doing my own stuff. I'm trying to fix this. But do you have any recommendations? And rather than just knee jerk and go, Oh, I'm going to go ahead and yeah, just do this and this and this. I started thinking about it. I went Holy cow, my hospital. Medical city Plano.Eric Rieger  Right. Ken Brown  Is a level one trauma center and is designated as a magnet hospital for stroke, acute stroke rehabilitation. Eric Rieger  Okay. Ken Brown  So they have a whole team that if you show up with a stroke, it's just like a heart attack. They're badass. Yeah, they show up with like this team of interventional neurologists, and they get in there and they do all this stuff. So I'm sitting there. My quick side note, I'm picking up my family from Mexico, because Luke was just playing tennis. You know, that was the the personal part of it that we didn't get into, but just assume it's tennis. Eric Rieger  Assume it's basketball.Ken Brown  Yeah. So I called. I called the stroke rehab unit. And I spoke with them with the nurse. The manager, nurse and she was so cool. She's like, She's like, hey, yeah, blah blah blah Yeah, we were our rates are this. This is the protocol. I'm like, what's a protocol for diet? We don't have one. What's protocol for supplements? We don't have one  i'm like, Oh my goodness, let's look at this. So I called our secret weapon. And I started to get into it and it's a much bigger bite to chew off then we can do in this sort of quick episode. So this quick episode, I want to just focus on the endocannabinoid system and stroke. Because what we do with stroke victims is that we basically do everything wrong. Eric Rieger  I believe it. Ken Brown  In the hospital. Eric Rieger  Yeah. Ken Brown  And when I asked him, like, what is the typical diet? She's like low fat. Eric Rieger  What's the science behind that? Ken Brown  Exactly. And we know that the carbohydrates increase inflammation and this and that. I'm like, Well, what else and she's like you had traditionally everybody gets put on a Staten, which causes some brain inflammation, because we're chasing numbers on cholesterol. Anyways, keep listening, because we're going to end up doing another episode on we're going to develop a protocol that I hope everybody adapts, and the nurse was like, that would be amazing. nobody's talking like that. Because everybody has this hammer. I mean, we bring these people in, they have a stroke. And one of the most important things is sleep and what do we do just disrupt sleep, check vitals blood sugar, and all this other stuff. So basically, we focus up we focus on all this stuff. So I called a couple neurologists, and was like, Hey, man, what's the or Hey, woman? I don't want to be sexist here. I'm like, Hey, what are we doing here? What's going on with the you guys are crushing it. So basically they focus on the awesomeness science of clotbusters like tpas and blood thinners. And then they rush in with this incredible technology that is amazing. Where they get in and they do like cardiac clot, like the same thing that the cardiologists have been doing. That they end up just sort of extracting these clots and they just crazy stuff. It works, but then they don't think about anything else,. So here a gut check project. I feel like we check our egos at the door and we look and go, how can we do things a little bit better? I feel like that this conversation that we're having could be the beginning of something bigger. Sure. I feel like we're missing a ton of stuff. This is not to bash traditional medicine at all. This is just a glorious example of how medicine save lives. But unfortunately, if all you have is a hammer then everything's a nail. So we're going to go ahead and look at that today. Eric Rieger  Let's do it. Ken Brown  I'm gonna do one brief thing. Because we always do in in the news, we always do our personal lives in the news, mostly because it's a win for me. So I'm just whenever I find news that is pertinent to me, I'll talk about it. And I'll just kind of, like most people just sort of ignore the stuff that bothers you. Bottom line is a study just came out. Looking at coffee. Eric Rieger  Oh, I love coffee. Ken Brown  So February is Heart Month, right? Eric Rieger  It is. Ken Brown  So everyone talks about Heart Month, and we're strokes are almost parallel to heart. So the same vessels that can ruin your brain can ruin your heart. You're gonna die either way. Let's start fixing it. Eric Rieger  Yeah. Ken Brown  So a study came out this last Thursday. So just a few days ago, in a journal called PLOS biology that I follow, which always looks at like new and upcoming research, as it find it. As it turns out, we know that coffee is good in 2017. There was this big meta analysis that show that help with diabetes. And also helped with cardiovascular disease and different things like that. But we really never, we always thought it was the polyphenols. So these guys looked at this and they took mouse models. And what they showed is that the caffeine plays a role. Eric Rieger  Nice. Ken Brown  Yeah. In case you haven't guessed that I drink just tons of coffee. Eric Rieger  I didn't have to guess I see it all the time. Ken Brown  Alright, so anyways, they took mouse models, and what they showed is that when you drink four to five cups of coffee equivalent in caffeine, you actually improve the mitochondria in the heart cells. They even show that the mitochondria is that you know, it's the powerhouse of the cell. It's what makes you walk around. It's what drives every single cell they found a protein called p 27, which is stimulated by caffeine. And when they gave heart attacks to mice, and then they gave them coffee, the mice that got the coffee, or the caffeine equivalent, recovered quicker, knockout mice that they took away the P 27 protein or whatever, they all died of heart attacks. So quick little thing in the news, coffee good, helps diabetes helps heart disease. And now we realize that it improves mitochondria. So I got to thinking and I was like, wow, the whole mitochondria is our aging thing. I found an article where they looked at old an aging mice, the more caffeine that they took in during the day, the more that their mitochondria were younger, and it was an anti aging molecule. So polyphenols plus caffeine, it looks like.Eric Rieger  it's really interesting, brief note, and maybe we should even do a show about caffeine and the systemic effects because during anesthesia school, we talked about why caffeine does what it does, and the jitters. And essentially, the way it was explained to us and shown to us is that they didn't know the exact mechanism, but they could tell that the threshold that it took for like a neuron to fire was lessened. So what it does is it lowers threshold to elicit an action potential. It would make sense that somebody who's a little bit older, basically you're taking down the barrier. And now you've got demand making the mitochondria useful. I mean, it's...Ken Brown  Yeah, I like where you're going with that.Eric Rieger  It's all kind of systemic, we'll get to that. That sounds like a an interesting... Ken Brown  So that's just basically in the news Heart Month now we're doing this... Eric Rieger  And if you think this episode's fast, wait til we do the caffeine one.Ken Brown  So this is just one of those things where we're, we're trying some different stuff out but one of the biggest problems I had is I called the stroke center and they do not have a protocol. And then when I called the neurologists and and I said one thing I was like, have you guys ever thought about the endocannabinoid system, in your specialty.Eric Rieger  No, they haven't.Ken Brown  Not only No, it was a hard no with that BS. Eric Rieger  Sure. Yeah. Ken Brown  So rather than get an argument and like, we'll just do a show on it.Eric Rieger  Yeah, we will. Ken Brown  So this show should be titled the anti bs side of endocannabinoid system and stroke. Eric Rieger  Let's do it. Ken Brown  Alright. So, once again, geeky sorry, we've done two geeky shows in a row. We're gonna have to start having, you know, just playful things. We have to have a comedian on like Joe Rogan or something like that.Eric Rieger  Eventually.Ken Brown  Yeah. It's probably a little premature. Alright, so let's talk about the endocannabinoid system really quick. I'm gonna throw it to you, and I'm gonna let you just to describe to everybody what is the endocannabinoid system. Eric Rieger  The best application that we know today that I understand is it basically functions as a great communicator, between our nervous and our immune system. So you have these two systems and basically it functions as the regulator. It's the one that prevents one from being overstimulated and driving the other one to do something that you don't want it to do.Eric Rieger  100% So the way that I describe it to my patients, our endocannabinoid system is like any other system in our body, you have a cardiovascular and neurologic. The endocannabinoid system works like a traffic cop. And what it does is it says we need more inflammation here. Whoa, you're overreacting. Why don't you just calm down right over here? So keep that in mind, because as we talked about the endocannabinoid system, now we're going to talk about how does the endocannabinoid system relate to stroke. So unfortunately, we got to talk a little bit about strokes. And I like history you like history. So, Hippocrates, the father of medicine first recognized strokes over 2400 years ago, we got 2400 years to figure out how to fix this. At that time, they called it apo Plexi, which means struck down by violence. So 2400 years and to this day stroke still kill 140,000 Americans. That's one out of every 20 deaths. Eric Rieger  Wow. Ken Brown  Someone in the United States has a stroke every 40 seconds. That means every four minutes someone dies. Every year more than seven Well, let's just call it 800,000 people in the United States have a stroke. About 87% of all strokes are ischemic stroke. Which means it's decrease of blood flow. And $34 billion are lost every single year due to strokes. Stroke is a leading cause of serious long term disability, stroke reduces mobility in more than half of stroke survivors. So the, if the actual death is not shocking enough. It's your health span is reduced. And you and I always talk about lifespan versus health span...be healthy. So what I'm going to talk about right here is crazy that this is not being implicated. This is not are not implicated not not being used in the traditional sense.Eric Rieger  Gotcha. Eric Rieger  All right. So, right now, the cool science going on is that we've got all this intervention, we got labs, we got stroke centers. We did we're, I feel like we can do a whole episode on just the diet, the supplements, everything around lifestyle on a stroke. And we're going to do that just like we're gonna do the butyrate episode coming up and just like we're going to do, every time we get into a topic, we start digging deeper, and we learn a little bit more. So today, the fact that these neurologists are saying, oh, food is Bs, well, I'm just taking on the big 600 pound gorilla. I want to say, Well, I want to know what you're not even thinking about endocannabinoids are you? And they're like, that's really bs. Now we're gonna get into it. So it is there's tons of research in the animal model of how to target so this topic of this podcast is the endocannabinoid system and strokes. Holy cow, there's tons of data on this and we're not even talking about it. I'm at a, a world class Stroke Center. Where we save more people than like anyplace else. We've been given national recognition. If if you're the CEO of who owns our house, the old colombia The HCA HCA if you're the CEO of HCA, pay attention because I can say more people for you, because as it turns out, there's lots of confusing data out there. And I took the time to go ahead and look at some of this. It's really cool. Basically, we've already reviewed the endocannabinoid system. Now in this endocannabinoid system, there's two primary receptors. We're learning that there's more for the Wil Clydens of the world that are super smart, and they understand that there's a lot more than that or the Chris Kressors and people like that. But for the general public, there's two receptors, cb one and CB two, there are the traffic cops, right? So that's what we have to realize. So as we alter the endocannabinoid system through different things, we know that the endocannabinoid system is associated with Parkinson's disease. It's associated with Alzheimer's and multiple sclerosis. The only drug approved is epidiolex for seizures. This is part of the problem. It's the confusion of what's going on? People say what does the FDA say? Well, did you know that the FDA just missed their mark to present to Congress on February 20? No? Ken Brown  Yeah, they missed it. That's another news article. They did not come up with a consensus statement on CBD when they were mandated by Congress to do that, because everybody's so confused. Eric Rieger  Wow, you know, I didn't know that we should look into that.Ken Brown  And we know that in those studies of epidiolex, there was 86% side effects and all the things. So what I'm going to get into is the full spectrum, what we're looking at here, so stick with me here I know that I'm kind of bouncing around. What I'm trying to do is set the stage that the endocannabinoid system is intricately related to the disease known as a stroke or the event known as a stroke. So knowing that the endocannabinoid system is important in Parkinson's and in Alzheimer's, dementia and such like that, what we want to try and figure out is how is the endocannabinoid system related to similar things which is Parkinson's and dementia are inflammation in the brain. Well, the stroke is immediate inflammation. Alright, so CB one receptors. I say this only because the argument will come up will be like, well, I found some studies that showed that there were some studies looking at CB one receptors were when you had knockout mice, they did better. Other studies show that they did worse. Some said that this and that. And so I was going through all this literature going, this is silly. This is we don't really have a conclusion. So the bottom line is, think of it this way. And I will use a Will Klyden quote, it is a symphony. It is not one instrument. When you are looking at the endocannabinoid system, if you are just going to focus on one thing, which unfortunately researchers do because it's impossible to account for all the other variables, all I can say is CB one is intricately involved and it may be involved in a negative way. When it becomes a stroke. So if Your endocannabinoid system is not in tune. It can make it worse. Just like a symphony where you have the brass section which is just screwing it up. You've got the rest of the symphony playing Mozart and you've got some other people just kicking some cake. Eric Rieger  An orchestra with only symbols is not very entertaining. Ken Brown  No, it's not. So I bring this up because when you start trying to read it and debate it and look at it, you can be thrown curveballs. One of them is that and, but then you dig deeper. And there's all this literature on this instrument called CB two. Cb two is the other instrument, cb one, cb two are the two receptors. Now we're learning more about the endocannabinoid system, the data is much more straightforward on this. Basically, multiple rat models have shown that when you give an agonist or a CB two activator, both pre stroke and post stroke you decrease the amount of damage, so you can actually prevent what's going to happen. And then once it happens, you go, Oh, we need to stimulate that. Keep that in mind. Because to prove a point further, when CB two was blocked, the rats had tremendously more damage and they had residual effects. So just by saying the endocannabinoid system, and they're like, oh, it involves CB one, cb two, which is the top level that everybody talks about. The interplay is way more, you gotta let the body do what it wants to do. can't shut one off, you can't turn one on. You can't encourage you have to be able to let the body do what it wants to do.Eric Rieger  No, definitely. And that's, that's really not that different than lots of different drugs which they thought they pulled them out of racemic mixtures. And then what racemic mixture means is you've got two different variations of the same molecule and one's active and one isn't But then they learned that sometimes if you do one and try to isolate it, you actually caused damage. Whereas before, if you had them together, you didn't have that damage. And it's played that multiple times.Ken Brown  So clearly CB two receptors play a very key role. What I'm trying to prove here is that when we take these animals and we mess with these receptors, we either increase the damage or we decrease the damage. So the theory is that the endocannabinoid mediated modulation of the inflammatory process is the reason why people get better. So in other words, we always talk about inflammation. Now they're realizing that the CB two receptor mitigates the inflammatory process during an ischemic event. Eric Rieger  That's pretty important. Ken Brown  It's really wild. So now what actually interacts with these receptors? So if somebody's never heard these terms before, they're like, man, they're talking weird stuff. They're talking CB one, cb two, don't worry about that. Cb one, cb two are just two likeminded things that are trying to make you better. As it turns out, we can say this about every single system in the body there's going to be interactions, downplaying in the gastrointestinal system. Histamine will stimulate a cell which will produce gastrin, which will increase the acid production blah, blah, blah, we know this Eric Rieger  But histamine could, the same molecule on a different receptor could cause a completely different Ken Brown  100%. So why would the endocannabinoid system not be different than every other system? Eric Rieger  It's it sounds to me like it's very normal. Ken Brown  You know what I keep saying? We're gonna have Endocannabinoid ologists I'm gonna be the first endocannabinologist. I'm gonna get myself a title. So somebody had to be the first black belt or something. I mean, why don't I just rushed to be like? I'm It! I'm it! Eric Rieger  I'm the BBECS. Ken Brown  Yeah. Alright, so there's two endocannabinoids. What I mean is you make your own CBD. And those two things there's we're learning that there's lots of them. But for the basics it's anandamide and 2ag. So knowing that you have these two endogenous meaning two endocannabinoids that stimulate CB one and CB two now we're just learning what they do. Okay. So 2ag goes up dramatically following a stroke.Eric Rieger  So trying to do some damage control.Ken Brown  We don't know...Eric Rieger  We don't know...Ken Brown  We do know that when anandamide is the soft light that is always on when you go through a stressful event 2ag turns on switch the flashlight. So the feeling is that that 2ag is the fight or flight Endocannabinoid. Eric Rieger  Oh, okay. Ken Brown  Yeah, so when you need it, It ramps way up. In situations where there's cell damage, it doesn't know the difference that there's cell damage possibly it's ramping up because it's like we're in fight or flight mode. We're dying here. Eric Rieger  Where's the inflammation? Ken Brown  Yeah, so these guys are postulating that when you block 2AG, the stroke damages less. My feeling is well, what if it's doing something someplace else? Like, what if you needed that 2ag burst? So when you have fight or flight, you need it for different things. Sure. Some people would say, oh, you're having a fighter flight. You're being chased by a saber toothed Tiger your blood pressure's up. We should give you blood pressure medicine. No, it's the right thing that should be happening right now. Yeah, I need the blood pressure to pump the blood. So we know that that to ag is your fight or flight Endocannabinoid think of it that way the flashlight Anandamide is the one that you want up, that is the Eric Rieger  Parasympathetic, your rest and digest. Ken Brown  It's the it's not quite the parasympathetic one, but it's the one that is your baseline that should always be filled, that anandamide tank should always be filled. 2aG. We're gonna learn more about it in the future because we haven't studied that as much. But when you have 2ag around, blood flow gets reduced. So the damage is worse. And this is really interesting because when your baseline anandamide is low, your 2 a G will overshoot. Eric Rieger  Okay.Ken Brown  So they work like a seesaw. So if you can get them in balance, we always talked about balance and in sync. When your anadamide is full and your 2ag is full, they never really mess with each other. In a situation where you're depleted in your endocannabinoid system, then you will have the propensity to have too much 2Ag and your anandamide is in fight or flight and your endocannabinoids will keep producing the two AJ, Eric Rieger  That is very, very interesting. So in other words, what we want is to never be in a position where our our ECS is low on what it needs to function. Ken Brown  100% so anandamide we're now learning is probably the baseline Endocannabinoid that controls the day to day response that you're having. 2ag turns on when you need it to turn on. So, although the animal models show that 2ag increases significantly causes vasoconstriction and all this stuff, we're learning that okay, maybe, maybe this is my theory, the stress and the chronic disease. Listen to this one more time here, the stress and the chronic disease that led to a stroke. Meant that your anandamide was being depleted and your body was getting ready for the event. You're 2ag going up. So stress, lack of sleep, diet, all have been shown to decrease our anandamide levels, stress, lack of sleep and diet have all been shown to be linked to cardiac and stroke and every other event that we talked about Eric Rieger  Time and time again. Ken Brown  So when I grab a neurologist and I say, Have you ever thought about the endocannabinoid system, the religious stroke and they're like, that's BS. I'm being nice about how they said it to me. Are you kidding me? Eric Rieger  Well, it's...Ken Brown  we're missing this huge, giant piece.Eric Rieger  It's kind of sad because the research isn't it's not one paper. This is it's ubiquitous, it grows every single day. I think people have over the last 50 years have forgotten that innovation brought us to where we are now. I mean, we used to not have TPA we used to not have kumudin and we used to not have these things I mean it those were also new introductive things for us to figure out.Ken Brown  I was talking to somebody yesterday and they were like you know what's really skewed when you look back at like the the average lifespan when you when you factor out the deaths at birth people still live to like 60 and 70. Like, like, but there was so many things that killed babies Eric Rieger  Oh, you mean long ago, Ken Brown  Like long ago. So when I say that Hippocrates was describing strokes, and you know, 2000 years ago, whatever. But this is so fascinating because think about this, if you keep your anandamide levels optimal like adding Atrantil which blocks an enzyme that breaks down your own anandamide levels. That is something that we can look at, and I think that's part of the next episode. But when you take CBD, so our CBD product here, when you take a good quality CBD it doesn't even bind directly to CB one or CB two. We know that a full spectrum product has many cannabinoids and other molecules that bind to certain receptors. We also believe that CBD will play a role in helping the body to produce more of its own Endocannabinoids. So what I tell my patients is that if you take CBD, you're going to increase your own anandamide levels. You take CBD plus Atrantil, That's the signature package and you're going to make sure that you block the enzyme that breaks down your anandamide Eric Rieger  So it lasts longer. Ken Brown  So it lasts longer and the neurologists like there's no science in this. Okay? So I had to dig deeper, or our secret weapon dug deeper for me. In rat models, infusing CBD into the brains of rats significantly helped to decrease the amount of damage and help recover in stroke. Really CBD does nothing? They actually injected CBD into the brains of rats that they cause strokes. And it actually blocked the ischemic event. One to One. Crazy! Eric Rieger  That's noticeable. That's a reproducible event.Ken Brown  Then in another study, they showed that the blood brain barrier sealed its tight junction and decreased brain swelling post stroke when you gave them CBD, Eric Rieger  Which is huge. I mean, I know it sounds really, really technical, but trust me, that's not nothing.Ken Brown  Remember the whole reason that I'm even talking about this is because our friend Tim just called me and said, Hey, man, my dad's in rehab, and they're not saying anything. Well, it was shown that continued oral administration post stroke at one week, and one month reduced the volume of infarct and improved neuro behavior on autopsy. So they're taking this it showed that CBD reduced white matter injury reduced glial response, meaning that the cells did not react to it. And it increased BDNF.Eric Rieger  Which is what you need for repair.Ken Brown  You need that for repair. Shit! This is nuts. Yeah, we're over here saying that CBD isn't do anything where the endocannabinoid doesn't have it and I'm finding article after article and these guys are finding amazing data BDNF. If I the first thing I would do would be to the first thing I would do would be to put people we're going to come up with a whole protocol. And I'm gonna go to HCA and don't be like, everybody that has a frickin stroke needs ABCD and one of them's gonna be frickin CBD. This is ridiculous.Eric Rieger  We've got some opportunity, though. And not everybody's closed, we could probably find a couple of neurologists around here in the area that are at least willing to fairly examine data and dive in. And that's what we'll have to do.Ken Brown  We're gonna end up having to go into this. I mean, the fact that I called my own Stroke Center, and the nurse sheepishly said, Well, you know, they do the usual things that put them on a low fat diet, and I stopped her. Which, by the way, it's really cool, because when I called up, I was picking Lucas up and I was like, yeah, hey, it was nurse manager. And she's like, Yeah, and I said, I said, Yeah, this is, this is Dr. Brown. Do you have moment to ask couple questions. She's like, sure what patient is that? Regarding? I'm like, now I just wanna ask some questions. And she stopped. She goes the GI Doctor said, Yeah, she's like, oh, like, what do you mean uh Oh, she's like, I've seen your show. I'm a little scared what you're gonna ask. I'm like alright and so that's how we got this talk. So right now new models are looking at immediate administration of CBD and hyperthermia. So somebody out there is saying, if we make them cold and give them CBD, and it seems to be a synergistic effect Eric Rieger  Wasn't that long ago, people thought that making the body cold was a bunch of Hocus Pocus crap, too, right? It really wasn't that long ago. And so now we've returned to its natural element, all we're doing is reducing body temperature. But however long ago it was, I can remember people saying, Well, you know, they're trying the cryo, and at first like, hey, maybe it works. And then suddenly, we saw lack of decrease in loss of neural function, you know, make believers.Ken Brown  So I want to play devil's advocate, and we talked last time that we're going to do some sort of like contest. Here's the contest, for the listeners. All right. There is a reference when I was looking at all this stuff, one reference, there was an article on stroke in cannabis ingestion, where they said that cannabis ingestion increases the incidence of stroke. So and then I went and found the article and realized there's a lot of other factors associated with that, much like the FDA article that we did on liver failure. It's very much like that. But the FDA is using an article like that and ignoring everything that I just said. And they're using that. So what I propose is and you figured out, you're the you're the techie guy, let's do some sort of giveaway where if somebody the first person that messages us in one way or another email, Instagram, Facebook,Eric Rieger  Paul we're gonna need help with that, Ken Brown  yeah, snail mail, whatever, I don't know. That references the article and puts the author's names down because the author's names you'll you'll really, you'll You'll definitely find the article when you find this author's names, that I think we should give them a signature package Eric Rieger  Signature package if you find the well hidden, gem about marijuana, cannabis smoking and stroke causation, right? Ken Brown  Yeah. So spoiler alert. So I'm going through a whole Rick and Morty Phase I should do.Eric Rieger  If you're not watching Rick and Morty, that's one way to decrease anxiety.Ken Brown  All right.Eric Rieger  This episode is brought to you by Rick and Morty.Ken Brown  I cannot believe it's took me this long to find that show I am I come home and that's 20 minutes of just complete giggle time, just total giggle time. Alright, so lots of cool animal data. I just explained what I think shows that the endocannabinoid system is intricately related to strokes and how we can improve it and in some ways if you try and mess with it, make it worse. Eric Rieger  So let's I know we did a quick episode but let's just do a quick rundown to make sure that everybody who's listening or watching can make their own crib notes. So, essentially, before and after a stroke, you can prepare your body for better recovery or prevention of the stroke itself that comes from having a healthy endocannabinoid system your ECS. How can you fortify your ECS? You make sure that you have enough sleep, you make certain that your diet is rich in polyphenols, which of course you can supplement with altrantil, and you make certain that you have the correct macronutrients for your ECS to lift up which you can get with a formidable or reputable CBD which kbmd health has both of those things. So in essence, if you want you don't know how you're going to get hurt, a lot of people don't know that they're going to have a heart attack today had a patient today. 172 poundsKen Brown  I thought you were gonna say 172 years old and I was like wowEric Rieger  Six foot one Well built man. 172 pounds 49 years old, has been doing jujitsu and Taekwondo for 30 something years. Heart Attack had a heart attack back in 2012. Undiagnosed cad, the guy's got, which is coronary artery disease, the guy has two stents in. My point is, nobody knows you don't know when you're going to be susceptible to something. So if you can, he was doing what he could, right he was exercising. So he was doing that part, right, but maybe something else that he could have been aware of...Ken Brown  I'm telling you, we're going to learn that the endocannabinoid system plays a much bigger role in this and we have seen diseases start happening earlier and all that stuff. Eric Rieger  KBMD health GCP code GCP save 20% on your signature package. Ken Brown  100%. So the bottom line is that there's tons of supporting evidence that exists for the involvement of the endocannabinoid system and the pathology of a stroke. Now clearly, this is super complex and we're just getting into it. And these researchers that are coming up with conflicting data about trying to block CB one or trying to agonize CB two, don't, don't do that what we really need to do is just make sure let your body do what it wants to do, when there is sufficient anandamide, which is the one that we know really kind of helps out, it will work like a traffic cop and keep the receptors in check. 2ag is probably necessary for certain things. So if we're doing this show, and you start to well, like I'm like, okay, bottom line is if I'm looking at you, and you're talking to me, and all of a sudden you start slurring your speech and half your face starts drooping. Yeah, you look like you're having a stroke. First thing I'm going to do is run and grab a whole bottle of KBMD CBD and I'm gonna shove it down your throat because at least we know in animal models, that makes a big difference. And then I'm going to go get a bunch of other supplements that we're going to do a whole nother show on that should be protocol for every single stroke center in the US. So much like the butyrate podcast, we got another one that we're getting into and I'm gonna bring a neurologist on and I want to bring an expert so that we can talk about it Eric Rieger  Small request, if I'm having a stroke and you're going to do all that CBD also get a speech pathologist to make sure I can swallow.Ken Brown  Yes, we will do all that if you're having a stroke, but I'm not trying to be a jerk about this, but we're going to finish the show first.Eric Rieger  Cool.Ken Brown  So, I mean, if it starts happening, try to do it towards the tail end of the show. You know, do you know that I've had four heart attacks since we've started this. This whole podcast show but I just suck it up, move on. I've had all kinds of health issues.Eric Rieger  That Believe it or not is going to go down to the books is our first short episode. Ken Brown  Well, we want to do a short episode because I feel like we're getting a little too sciency and I want your feedback. I mean, quite honestly, do you like the science you not like the science? Do you want the guest? Do you not want the guest? But when I find stuff like this, I have to let it out. And if you gave me Two hours, I'd be talking for two hours. So this is just a way to control the amount of vomit that I do right here. But it's so cool. How are we not doing this? Eric Rieger  I don't know. But I think I think will change though. And thanks every single week and thanks to Paul. we're gaining viewers. We're gaining listeners. This last week was a huge spike in the last seven shows. So thank you.Ken Brown  And you want to know what people are reaching out on their Insta they're messaging me on Instagram and they're asking medical questions. I love that I'm we're going to do shows on that stuff. So if you've got questions, let's do this. Eric Rieger  Definitely. that's gonna do it for episode number 34. That was strokes and the endocannabinoid system. We will in the show notes, go ahead and add unrefined bakery, their offer is still good. So save 20% if you want to have keto friendly, no gluten, paleo friendly, whatever kind of meal that you're after, and you feel like you can't have bread, they've got the solution for you unrefinedbakery.com use code, gutcheck and save 20% Ken Brown  Yeah,so once again, please do us a big favor. What we're trying to do is really spread this message of functional health. share it with everybody, get people calling in, get people asking because we've got the resources. we're gaining a little bit of traction here and this can be really fun. This was such an eye opener for me. Endocannabinoid system and strokes. All because somebody said my dad had a stroke Ken Brown  and Tim power thanks for reaching out. certainly appreciate it. gut check project. In the books go to gut check project. com share, like and share and we appreciate it.

The Green Nurse, Sherri Tutkus, joins Amie and Joyce again, this time to share her best ideas on how to use CBD to help find balance and joy this holiday season.  Sherri Tutkus is the founder of Green Nurse Group, an amazing resource for Massachusetts residents looking for help navigating the ever expanding world of cannabis and CBD health and wellness products. She is a cannabis healer who wants to educate, empower and assist all her patients find balance in their lives.  The Canna Moms and Sherri talk about a range of products including CBD oils, salves, gummies and tinctures all curated by Irie Bliss  in Rockland, Massachusetts. Sherri explains the difference between broad and full spectrum CBD, and what she thinks are the best products for CBD and cannabis curious novices. Sherri shares her excitement for the upcoming American Cannabis Nurses Association in New Orleans right before Amie shares her favorite thing this week, the Paleolithic Pipe she picked up at the Harvest Cup. And, of course, Sherri reveals her favorite way to consume. What we talked about: 2:10: CBD Reduces Holiday Stress 2:40: Endocannabinoid System and the Colorful Umbrella 4:17: THC and Anandamide 5:00: Runners High and The Endocannabinoid System 5:36: Up Regulating 6:00: What is Cannabis Nursing? 6:45: Causes of Down Regulating 7:30: Water Soluble CBD 8:35: Cannabis is a Nutrient 11:15: Irie Bliss Wellness 11:55: A State of Harmony 12:12: A State of Spiritual Bliss 12:55: Creating Need Based Products 13:25: Products for "Newbies" 13:50: Goddess Oils  14:25: What is an isolate? 15:45: Gummies and other CBD Treats 17:55: Broad Spectrum vs. Full Spectrum 18:50: Tinctures 20:12: Broad no THC: Full nominal THC 20:40: Daytime and Nighttime CBD 22:04: How Stacking Works 23:57: Topicals 24:20: Cost Saving Tricks 25:30: Levels of Healing and Getting Off Meds 26:20: Past Holiday Stories 27:23: More Topicals 32:15: Pet Products 33:40: Dosing Pets 34:30: Homemade Doggie Biscuits 36:00: CBD Flower Uses 37:35: THC vs. CBD Impacts 38:47: Feeling Good 40:02: Ways to consume: Medically, Recreationally and Irresponsibly 40:35: Green Nurse Events! 43:35: Marissa Fratoni 47:00: American Cannabis Nurses 48:20: Holiday Food Plans 51:54: CBD Drinks for the Holidays 53:00: Terpines 53:24: CBD Components 54:14: Amie's Favorite Thing 55:20: Electric USB Lighters 56:51: Review of Products 1:00:40: Favorite Way to Consumer            

Jewel Zimmer has a more interesting career journey than most of us, and they’ve all led her down the inevitable path to her company Juna. Her life seems to have revolved around food with a mother and father both in the food industry, and a few of her former careers including that of a fine-dining pastry chef, a sommelier, and a chocolatier, not to mention her foray into the skincare industry. She went to school for chemistry before changing her mind and becoming a licensed esthetician. To say Jewel is intelligent, brave, and has a knack for seeing the future of industries would all be an understatement. During this interview, thanks to her chemistry background, Pablo and Jewel dive deep into the compounds and chemicals that make cannabis unique from terpenes to cannabinoids to flavonoids to adaptogens. They also discuss some of Jewel’s incredible journey into the cannabis industry via chocolate, they discuss tinctures, CBD, how cannabinoids affect your body, and much more. You can learn more about Jewel’s company, Juna, and the tinctures she has to offer at her website https://juna-world.com. You can learn more about Vanguard Scientific at our website: https://vanguardscientific.com/ If you want to learn more about the topics we researched you can check out the links below. San Fransisco’s Cannabis History: https://www.7x7.com/from-mark-twain-to-modern-day-san-franciscos-history-as-americas-canna-2276589763.html Bean to bar: https://www.americastestkitchen.com/articles/1000-bean-to-bar-chocolate-trivia-everyone-with-a-sweet-tooth-should-know Mendelian Genetics: https://knowgenetics.org/mendelian-genetics/ Polyphenol Antioxidants and Anandamide: https://www.medicalnewstoday.com/articles/319728.php https://en.wikipedia.org/wiki/Antioxidant_effect_of_polyphenols_and_natural_phenols https://www.sciencedirect.com/topics/medicine-and-dentistry/anandamide https://www.leafly.com/news/science-tech/meet-bliss-molecule-anandamide-cannabinoid https://www.exploratorium.edu/exploring/exploring_chocolate/choc_8.html https://www.youtube.com/watch?v=NpH9C8-y708 Full Spectrum: https://www.leafly.com/news/science-tech/full-spectrum-cannabis-extracts-explained MCT Oil: https://www.medicalnewstoday.com/articles/320251.php Terpenes: https://en.wikipedia.org/wiki/Terpene Flavanoids: https://www.livescience.com/52524-flavonoids.html Cannabinoids https://adai.uw.edu/marijuana/factsheets/cannabinoids.htm https://www.analyticalcannabis.com/articles/the-difference-between-cannabinoids-and-terpenes-311502 Entourage Effect: https://www.cannabisbusinesstimes.com/article/ebbu-entourage-effect-cannabis-guest-op-ed/ Audio Production Assistance and Music Credits: Jason Huskey

Full show notes @ https://thesternmethod.com/allan-frankel Dr. Allan Frankel is one of the world’s leading authorities on dosed cannabis medicine. He started his career as a traditional doctor, but after an extremely serious health issue was reversed when friends introduced Dr Frankel to medical cannabis, he began researching the plant and its healing properties. In 2007 he sold his practice and became a cannabis doctor. Now Dr. Frankel applies his knowledge of all aspects of the cannabis plant and its therapeutic value to the treatment of cancer and other serious medical conditions. ***Resources Mentioned*** Greenbridgemed.com *** In This Episode: Cannabis has been widely shown to improve a cancer patient’s quality of life. In this episode, Dr Frankel gives me the run down on how he provides dosed, predictable cannabis medicine to his patients to help them manage the side effects of conventional treatment. Plus he shares the specific formula he uses to calculate the right dosage.  We discuss the anti-cancer properties of cannabis along with Dr Frankel’s own clinical experience of cannabis as an effective cancer treatment. We talk specifically about the benefits of whole plant cannabis vs isolates, and how the cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) can help manage pain, treat nausea and vomiting, and treat the anxiety that goes along with fighting cancer.  So if you’re considering adding cannabis to your alternative treatment protocol, this episode is a must-see.   What led you to become a cannabis doctor? Was it your intention to work with cancer patients? Got a virus that went to his heart and was given 6 months to live without a heart transplant Went to LA and friends introduced him to cannabis plants which immediately improved his mood and reduced anxiety. Within weeks he was running up the stairs After this experience, started studying cannabis and its medicinal properties.  Are you seeing mostly cancer patients? About a third are cancer patients The dosing for anti-cancer is based on treating side effects of chemo Dr Frankel follows low dose protocol used in clinical trials. Total of 130mg daily (30-40mg of CBD, THC, THCA and CBD A)  Acid molecules (THCA and CBDA) are gaining more attention due to specific anti-cancer properties What’s the difference between hemp and cannabis? The level of THC. Cannabis contains more than 0.3% THC, hemp is 0.3% or less Dr Frankel recommends using the whole plant rather than stripping out a single molecule Is oil the only option when it comes to therapeutic use of cannabis? Salves can be used for pain and neuropathy 30mg or more of whole plant CBD to prevent neuropathy THCV reverses neuropathy 30-40mg daily of each of the four cannabinoids is a good all round anti-cancer, anti-pain, anti-nausea treatment  Can you explain the dosing in more depth? The actual THC or CBD in 1 gram of cannabis oil is around 750gm. The other 250mg is made up of other cannabinoids DIY Formula to produce a reliable dosing tincture of 20mg per milliliter You have 750mg or 75% CBD oil If you want to take 20mg CBD a day then divide 750 by 20 Take this amount of a thin oil like MCT, coconut or olive oil and dissolve your ‘gram’ of CBD oil in it You now have 20 mg of CBD per milliliter of your oil mix Take ½ a milliliter 3 times per day  More cost effective to dose this way If we have an internal cannabinoid system, does this mean we should regularly consume them? Endocannabinoid system was developed 1.2 billion years ago, well before the plant-based cannabinoid system (fibrocannabiods)  Any species with a spine has an endocannabinoid system  The effects of cannabinoids on the endocannabinoid system can be measured Anandamide, one of the components of our endocannabinoid system helps monitor and control cancer.  Cannabinoids can bump up our endocannabinoid system and this promotes cell apoptosis, autophagy etc of cancer cells Most common symptoms of endocannabinoid deficiency is migraines, bowel problems. Fibromyalgia, anxiety, disrupted sleep. More common in females What type of cancer patients do you see? Most patients are on conventional treatment protocols alongside cannabis Ballpark of patients who do well on cannabis alone would be 2 out of 3 Lower dose chemotherapy combined with cannabis to mitigate side effects and toxicity  Can cannabis prevent long-term chemotherapy side effects? THCV can prevent and reverse neuropathy  CBD is protective of the brain and kidneys What is THCV?  Only available in California Raises your mood - treats depression Mix with THC to treat migraines.  Shown a reduction in symptoms and ability to stop progression of parkinsons in animal studies CBDA - best to treat nausea THCA and CBD - bladder problems, repairs mitochondria, treats myasthenia gravis How much do you take into account strains? We don’t know enough about strains Strains are defined by the other flavinoids, plant waxes and other molecules What are your thoughts on high dose RSO (Rick Simpson Oil)? Sometimes people have good initial response with high dose then cancer comes back Some people do well on RSO Cannabis is a bimodal drug and has opposite effects with high vs low dose 1gm dose is a very high dose - potentially toxic levels Studies of low does (30mg daily) cannabis show great results Do you see children in your practice? What considerations do you make when it comes to kids? See autistic kids on anti-psychotics, ADHD kids on amphetamines and benzos  Cannabis much better options than these drugs How would you dose a child? Doesn’t dose by weight - start lower and see how it goes Are there any interactions or complications you are aware of? Cannabis and pharmaceuticals - depends on the dosing, type of cannabis and how it’s taken Oral is biggest issue as both go through the liver Whole plant medicine is different from isolate - dosage is lower Biggest concern with isolates is that we may see more drug interactions Any last comments? Study showed CBD prevents tumors developing tolerance to chemotherapy  Dr Frankel recommends anyone with cancer to use cannabis medicine Follow Dr Frankel Greenbridgemed.com - Remote consults are available If you have a question or comment about this episode let us know below!!

Learn about how 3D printing could shape the future of fashion, from best-selling author Dana Thomas. You’ll also learn about the difference between THC and CBD when it comes to cannabis; and, why the smartest people in the room are often the quietest. In this podcast, Cody Gough and Ashley Hamer discuss the following story from Curiosity.com about the difference between THC and CBD when it comes to cannabis: https://curiosity.im/2Lwa0jH Additional resources from Dana Thomas: “Fashionopolis: The Price of Fast Fashion and the Future of Clothes” on Amazon — https://amzn.to/2O2hqMX Official website — http://www.danathomas.com/ Follow @DanaThomasParis on Twitter — https://twitter.com/danathomasparis  Unmade — https://www.unmade.com/  Download the FREE 5-star Curiosity app for Android and iOS at https://curiosity.im/podcast-app. And Amazon smart speaker users: you can listen to our podcast as part of your Amazon Alexa Flash Briefing — just click “enable” here: https://curiosity.im/podcast-flash-briefing. 

In this epic episode, I hand over my reference of “endocannabinoid mentor” to our guest Emma Chasen - a leading Cannabis Educator and Industry Consultant. In fact, I call her the Endocannabinoid System and Plant GURU! For thousands of years, women have used cannabis to treat specific conditions, from inflammation to PMS. Emma uncovers how women possess more endocannabinoids like Anandamide in their bodies than men, often leading to a heightened sensitization to cannabis effects. Our entire conversation is electric as we tap into the future of precision formulas, identifying sneaky taboo products, and how particular cannabinoids help replenishes female health and beauty. With the abundant noise of productizing cannabis, I think we both would agree that the power starts with ourselves and by understanding the Intimate relationship between plants Phytonutrients impact within our unique personal biology. Enjoy as Emma and I go deep with you in our female empowering conversation. About Emma Chasen Emma has a mission to educate people on the science behind Cannabis so that they can take charge of their own healing. Emma has a degree in Medicinal Plant Research from Brown, has Coordinated Clinical Oncology trials with the Brown University Oncology Research Group, is formerly the General Manager & Director of Education for Farma and was named Portland’s Best Budtender of 2016. Emma is now a cannabis industry consultant and helps brands develop educational marketing collateral and educational programs to further elevate their brand presence in a competitive industry. You can catch Emma on her own radio show and podcast ‘This is Cannabis’ On Today’s Episode You’ll Awaken to: The critical importance of your unique endocannabinoid tone How we end up with an endocannabinoid deficiency How stress produces FAAH enzymes that block our bliss molecules. Our innate endocannabinoids Anandamide and AG2 -versus- plant Phytocannabinoids The truth on CBD and tolerance CBD as an allosteric modulator and how it shunts THC psychoactivy How cannabis and hemp seed differ The lock and key misunderstanding: How CBD only works by interacting with CB2 cannabinoid receptors (located all around the body), as well as non-cannabinoid receptors, such as the vanilloid receptor TRPV-1 and the serotonin receptor 5-HT1A How cannabis chemotype strains in the plant’s matrix alter our physiology to Terpenes relationship with cannabis in the body Extraction processes and how to identify synthetic ingredients How men and women differ in Cannabinoid benefits Straight up opinion on cannabis and pregnancy Next generation formulas Biggest Myth in CBD How the entourage effect can significantly alter an experience CBD’s effects on Menopause and Hormonal fluctuations Emma’s incredible manifesto she’s awakened to this year Resources: Emma's Instagram @echasen Emma's Consulting Firm on Instagram @eminentconsulting Her personal Website Her Consulting Firm's Website Share the Love: If you like The Awakened Beauty Podcast…. Subscribe, Rate & Review via iTunes Visit us at awakenedbeautyhq.com for updates. Businesses: www.evoqbeauty.com | www.beautyecology.com Instagram @awakenbeautyhq Instagram @evoqbeauty Watch on Youtube at my channel: Awaken Beauty Podcast Shop natural health and beauty products with EVOQ Here’s how! Go to awakenbeauty-hq on ITunes and write your biggest takeaway in the rate and review section. Just pretend it says “ah ha” here!! Don’t just review the episode, I would love your ah-ha moment from this episode that is more specific so you can confirm your takeaway as you write, but also help others capture your brilliance. It’ll take 3 minutes from your day. What you declare will be life to others. So remember, go to I tunes to rate and review. Comment or question you’d like to ask Kassandra. P.S! Your review is not only paramount in helping others discover the show, but we also read each and every submission personally…and they mean the world to us. Love and Light! - Kassandra In the Meantime, STAY IN THE CONVERSATION! @awakenbeautyhq | #awakenbeauty BONUS *** Get the FULL SHOW NOTES *** in a full beautiful DOWNLOAD Take action & get the FREE PDF here! Additional Support and Proof! Listen and learn to this video more from leading PHD's from the 12th Annual SSEW Symposium, “The Exposome & Metabolic Health.” Speakers discussed the role of social relationships, chemicals found in everyday items like beauty and hair care products, and our food environments in encouraging negative health outcomes such as obesity and diabetes, breast cancer, and even Alzheimer’s. Listen Here

Dr. Dawson Church, integrative health-care researcher, the pioneer behind EFT Universe, and the bestselling author of The Genie in Your Genes, and his latest book Mind To Matter, joins our show in this special episode of the Elite Man Podcast! In today’s episode Dr. Dawson talks about the incredible power of the mind and how science is just now uncovering the true potential of what you can really do. He shares the latest ground-breaking research into epigenetics, meditation, EFT, and miraculous healing of all types of sickness, disease, illness, syndromes, and more. If you’re wondering how to use your mind to take control of your health and life, check this episode out now! *Download this episode now and subscribe to our channel to get more of these amazing interviews! In our episode we go over: What Dr. Dawson Church does in regard to integrative health-care research Why Dawson became so interested in alternative therapies What his life was like growing up and why it’s vastly different than his life today The various modalities that Dawson uses in his everyday life and the lives of those he teaches The science behind some of the alternative therapies and what they’re actually doing inside the body Dawson’s work with EFT and tapping and why he’s considered a pioneer in this field How EFT works and what happens inside the body when you do it correctly The conditions that EFT and energy therapies are effective for The best ways to use EFT for healing from various conditions Combining meditation and EFT and the best protocol for both Why Dawson considers meditation to be a stable alpha brain wave state How long it takes for most people to get into a stable alpha brain wave state The ideal amount of practice and time it should take you to get into the right meditative state What happens in your body during deep meditation How to actually know if you’re really meditating or not How to get yourself into the right meditative state What most people do wrong when they try to meditate or think they’re meditating The power of beta endorphin and other natural chemicals (nitric oxide, oxytocin, dopamine, serotonin, norepinephrine) that get released during meditation Anandamide – the bliss molecule and the incredible feelings that it induces in the body during meditation The dentate gyrus (inside the hippocampus) part of the brain that can actually grow when you meditate (one man grew his brain 22.8% of his brain in just 8 weeks) The fact that your brain will either grow or atrophy depending on what you do with your life and environment The importance of heart coherence and why it’s the secret to The Secret How to get yourself into heart coherence and make things happen in your life Manifesting what you want in your life by getting away from your local mind Letting go of your attachment to your body and the science of mysticism Quantifying supernatural or mystical experiences with scientific instruments Check out Dr.Dawson on: Website: mindtomatter.com Book: Mind To Matter Free Meditation Guide:  EcoMeditation.com   Sponsors: *Follow Justin on Instagram at Instagram.com/JustinStenstrom. *This episode is sponsored by my friends over at Vincero Watches. Typically, finding a watch that is high-quality, good-looking, and precise, costs a pretty penny. But Vincero Watches is here to change that. Vincero Watches creates exceptionally crafted watches and they do it without breaking the bank. You’re not going to find a better-made watch for this good of a price anywhere else. There is a reason Vincero has over 16,000 5-star reviews — because their bold timepieces masterfully blend form and function into one affordable timepiece. Whether you’re preparing for a first date or to crush a business meeting, a classic wristwatch is something every man needs. There’s always going to be an occasion where you want to really impress, and your Apple watch just won’t cut it. Vincero’s timepieces are showstoppers. I’m telling you you’re going to get complimented every time you wear it. I recently got my own Vincero watch and am absolutely blown away with how incredibly cool, high quality, and beautiful this watch looks. I’ve never owned a watch that’s looked as fresh as my new Vincero timepiece. I honestly am in LOVE with it! And it’s truly a head-turner! I’ve gotten so many compliments and people asking me where I got it. I’m telling you, you are going to LOVE your Vincero watch too. And the best part is… for a limited time Vincero is hooking my elite man listeners up! Vincero is offering 15% off your entire order with the coupon code ELITE.  Just head on over to VinceroWatches.com and use the coupon code ELITE for 15% off! That’s VinceroWatches.com and coupon code ELITE. *Today’s episode is sponsored by my friends over at Simple Habit, the creators of one of the coolest and most effective meditation apps I’ve ever used. You guys know I love meditation. I talk about it on the podcast ALL the time, I bring on guests who share different meditation practices, and I’ve used and tried so many different meditations myself. Every day in fact I meditate because, well, I just love it that much! I’ve tried dozens and dozens of apps, mp3s, and programs in the past but I’ve got to say Simple Habit is right at the top of the list for favorite ways to meditate. Simple Habit has hundreds of meditations available for free and thousands with their premium subscription. And there’s over 100+ experts on these meditations so you don’t get tired or bored with hearing the same voice over and over. And one of the things I love most about Simple Habit is that they have specific meditations for specific problems such as getting over stress, focusing better, helping you go to sleep, kickstarting your morning, and so much more. It’s not like so many other meditations that can quite frankly get old and tiresome really fast, Simple Habit has SO many different things to do and it keeps you very engaged and wanting to do more. Not to mention they also have cool walking meditations, commuting meditations, work meditations, and even meditations for when you have to do the dishes! And, did I mention, many of these meditations are short and to the point, taking up only about 5 minutes of your time! Yup, Simple Habit is truly a game-changer in the meditation space! For 30% OFF their Premium Subscription go to SimpleHabit.com/elite right now and get started! But make sure you go now as this offer will be gone soon and is limited to the first 50 Elite Man listeners who act fast! That’s simplehabit.com/elite! *Subscribe to our YouTube channel by going to EliteManMagazine.com/youtube right now!

In this episode, Kyle interviews David Krantz, Certified Epigenetic Coach, and an expert in nutritional genomics. In the show, they talk about the effects of substances via the implications on an individual’s genetics. 3 Key Points: Epigenetic testing is a bio-hack for boosting cognitive function and harnessing our creativity and ultimate human potential. There has been a lot of research done on genetics and the effects of THC. The body produces cannabinoids that activate the THC receptors internally, which varies from person to person. Each person should be seen on an individual level, and the more we know about our unique genetics, the more we can understand about our interactions with different substances. Support the show Patreon Leave us a review on iTunes Share us with your friends – favorite podcast, etc Join our Facebook group - Psychedelics Today group – Find the others and create community. Navigating Psychedelics Trip Journal                                              Integration Workbook Show Notes About David David works with clients on creating optimal epigenetic expression He uses people’s genetics as a guide to look at recommendations for diet, herbs, supplements, etc. He began looking at cannabis for recommendations and found curiosity in psychedelics too Epigenetics studies the effects of the modification of genetics It looks at chemical groups attached to the DNA itself and what happens to them over time Cannabis and Genetics The most robust area of research on genetics is THC David said he has seen some research on Psilocybin and just very recently that liver enzymes are responsible for LSD interactions It looks at the way people are metabolizing these substances When you ingest something or smoke it, it has a higher impact on the body, edibles are a great example Kyle brings up the curiosity of edibles impact being either physiological or biological Genetics show the body’s cannabinoid levels The body produces cannabinoids that activate the THC receptors internally There are two enzymes that break down cannabinoids in the body, Anandamide and 2AG There is a higher likelihood to use cannabis in a person with lower levels of endocannabinoids This makes some people high-functioning stoners, and others non-functioning stoners The substance is neutral, it's all about the body and how it reacts to it When the liver breaks down an edible, it makes THC more potent There is speculation that the slow metabolizers have a better chance of passing a drug test because they don't have a chance to convert 110HTHC to the COOHTHC Food and Substance Effects Kyle mentions someone who was drinking grapefruit juice everyday for 3 weeks, and it potentiated the effects of Ketamine In order to psilocybin to be converted to psilocin, you need a chemical in your body called alkaline phosphatase Vitamin C deficiency and Vitamin B-6 deficiency all both correlated with alkaline phosphatase deficiency David brings up his experience going keto, it worked really great for him, his energy levels increased, he lost weight, but his wife had a horrible time with keto Then he looked to genetics and it made perfect sense to him as to why it worked for him and why it failed for her Metabolism, biochemistry, genetics, and so many other factors impact a person's reaction to substances Gene Type Testing Apeiron David also mentions that with companies like 23 and me, they get their money from selling people’s genetic information He says Apeiron is focused on what you can actually do with the information, not just simply providing the results David says its super valuable for people to know these things about themselves, how to mitigate stress, how the metabolism works, knowing what to eat, knowing vitamin deficiencies, etc. Psychedelics in the Future of Epigenetics David thinks were going to see that the epigenetics of psychedelics are going to show the ability to overcome trauma When we look at people at an individual level, we all have our own idiosyncrasies and variations “Because there is no such thing as an average human, let’s stop treating people like average humans and start treating them like they are individual people. Let’s stop leaving out the outliers.” - David Taking an individualized approach to the psychedelic space is highly beneficial Links Website Instagram About David David Krantz is a certified Epigenetic Coach who specializes in boosting cognitive function and helping clients harness their creative and personal power. As a lifelong musician, David sees the various systems of the body as parts of a complex symphony. And, as a coach, he excels at fine-tuning those parts to create resonant harmonious health. David also serves as Director of Psychoacoustics at Apeiron Center in Asheville, NC where he develops sound-based tools for better mood, energy, and focus. Additionally, he’s an expert in the pharmacogenetics of the endocannabinoid system and has developed a proprietary genetic test for looking at individual response to cannabinoids. A biohacker by training and artist by nature, David enjoys working with others who have a deep passion for enjoying life.

Does Hemp Oil Have CBD? Best Practices for CBD Oil | Nutritionist Mike Tolani of Peach Vitamins Does Hemp Oil Have Cbd? Cosmic Hemp Oil With Peach Vitamins https://peachvitamins.com/ Peach Vitamins is a trusted provider of Cosmic CBD Hemp Oil, THC Free CBD Oil, CBD Isolates and other CBD products. CBD is known to help pain, anxiety, sleep, and much more! Buy Cosmic CBD Hemp Oil easily with Peach Vitamins. Hemp The whole plant CBD oil cultivars of Cannabis Sativa L. “industrial” or otherwise, contain a wide array of phytocannabinoids and high levels of Cannabidiol CBD. Historically, this variety of cannabis has not been bred for specific phytocannabinoid content or the sensations associated with imbibing them, but rather, for size, shape, and practical purposes. Its historical uses have ranged from creating textiles, twine, paper, to usage as support structures, due to its high fibrous content. Endocannabinoid System ECS To comprehend the significance of CBD to our health, we first have to ask the simple question, what exactly is our health? Is it just the absence of disease? If you don’t have symptoms, it must be healthy. How does human physiology work? How is it designed in general, every aspect of human physiology is based on the balance between opposites. A balanced mind, body, and spirit, will result in, systems which are in homeostasis, a state when the body functions efficiently. The stronger the body’s ability to stay in this state, the more robust and healthy you are. A balanced mind, body, and spirit, will result in, systems which are in homeostasis, a state when the body functions efficiently. The stronger the body’s ability to stay in this state, the more robust and healthy you are. Neurotransmitters and receptors in the body are like a key that fits into a lock, the neurotransmitter being the key and the receptor being the lock. A single neurotransmitter may bind with several types of receptors on the cell and have different effects depending on its location in the body. CB1 These receptors are known to be most prominent in the brain and bind with THC and can affect mood and emotions. In Ayurveda, it is said your emotions and mind can affect your physical being, thus this relates to appetite control and Inflammatory response. Emotional eating weight gain, loss of appetite and nausea while feeling anxious and stressed. CB2 CB2 receptors are more abundant in the nervous system and the immune system. Types of Cannabinoids Endocannabinoids Endocannabinoids are endogenous cannabinoids which are produced internally, by the body, for specific regulatory functions. Anandamide is a particular endocannabinoid of note, which interacts with the brain similarly to THC, helping regulate processes like memory, sensations of pain, and appetite. Phytocannabinoids Phytocannabinoids are exogenous cannabinoids are found in plants, and are generally absorbed by the body when we consume various plants, fruits, and vegetables. Some examples of plants which are relatively significant sources of phytocannabinoids include flax and carrots, while more aromatic plants, like rosemary, lavender, clove, oregano, cocoa, peppercorn, and truffles, contain more significant concentrations of phytocannabinoids. Cannabis, however, is king when it comes to phytocannabinoids content. To learn more, please visit: https://peachvitamins.com/learn/cbd-oil-for-sale/

Supplements and getting sunlight advice for an elder female; Genetic testing is another misinterpreted area used as excuse to not get vaccinated; The science behind the benefits of cannabinoids for treating many conditions and augmenting or replacing opiod drugs; Tweaks on using Neti pot with additives for chronic sinusitis; The brain processing problem explains cases when pain spreads all over the body; Topical testosterone for tendonitis and more ways to control pain

[Guest: Dawson Church] Join Dr. Edith & Dr. Dawson Church, PhD on a fascinating journey exploring how “Thoughts Become Things.” Dawson Church, is a legendary pioneer in the field of mind-body research. His latest best-selling book Mind to Matter synthesizes the latest research in epigenetics, neuroscience, electromagnetism, psychology, cymatics, public health, and quantum physics to demonstrate how powerful our thoughts are. Topics explored: * Bio-rhythms and their impact on our lives and meditation practice. * How resilience, love, and compassion are grown and cultivated in your brain. * A powerfully moving story about how the Northern California wildfires showed Dawson the importance of resilience and gave him an understanding of how trauma can heal. * Science is proving that our minds create our reality and that oneness—being in infinite consciousness—is more real than our material reality. * Cutting edge research demonstrating how meditation changes our brain, hormones, neurotransmitters and how different kinds of meditation can have different effects. * “Re-parenting” ourselves -- via tools like EFT tapping, grounding, massages, acupuncture, and self-care. * “Despite our current divided world, our society is actually in an upward trajectory of well-being.” * Neuro-chemicals change during meditation and literally make you one with the universe. * Meditation releases hormones like “Anandamide” that are more fun than any external drugs! * Dr Edith shares her first mystical experience in meditation, and how it changed her life. * How to integrate powerful meditation experiences or near death experiences into our day-to-day physical life. * Meditation may be the most important ingredient of “72hr Emergency Preparedness Kit!” * There's an inverse relationship between stress hormones and immunity with just one week of meditation. * Help a veteran through Dawson's Veteran Stress Project - https://stressproject.org/ * Dawson's most amazing laugh! ~~~ Dr. Dawson Church: https://dawsonchurch.com/ Learn more about Mind To Matter: https://mindtomatter.com/ ~~~ Connect with Dr. Edith - www.SuperWellness.com / www.DrEdithUbuntu.com Pick up your copy of SuperWellness on Amazon.com ~~~

Chocolate, seriously? Yes, seriously. To many of you listening, this episode will be a dream come true, as I'm discussing the health benefits, chemistry, nootropic effects, and so much more related to that product almost all of us love, in the form of sweet, nourishing chocolate. But before you get too excited, I'm definitely not speaking about inhaling multiple blocks of sugary dairy-milk crap in a day, it's all about the cacao bean, cocoa, and stuff so dark that it would make the Galactic Empire from Star Wars blush. Chocolate has been used for thousands of years by ancient cultures as a tool for healing, as well as something modern humans have eaten in large quantities when we've felt sad or bummed, though it hasn't been until recently that we've known scientifically why it's beneficial. And as you'll learn about in this episode, the benefits of chocolate are far from wishful thinking, as there's an incredible amount of science pointing to the fact that it can help us heal, boost brain health, assist our circulation, and so much more. In today's solo episode, I'm going to talk about why chocolate may help ward off diabetes, how it can potentially stave off brain diseases like Parkinson's and Alzheimer's, what anandamide is in chocolate and how it's been getting people "high" for millennia, why theobromine in chocolate is both good and bad, how to use chocolate as a nootropic, elevating your mood using chocolate, why you need the magnesium in cacao, how it may aid in sexual performance, and so much more. There are a ton of resources for you to consume (pun intended) related to this episode which you'll find below, and I'm sure you'll want to digest them (again, pun completely intended) in much more detail. If you're a biohacker, or just a chocolate fiend, this is likely going to be the sweetest podcast episode you've ever heard.   YOUR BRAIN ON CHOCOLATE: https://bit.ly/2intIkP  CHOCOLATE AND VIAGRA: https://bit.ly/2G87EU3  ANANDAMIDE IN CHOCOLATE: https://bit.ly/2DbMWBY  CHOCOLATE AND MOOD: https://bit.ly/2Z83698    CONNECT Connect with Leon The Alchemist online for more intensive biohacking, longevity, and performance advice daily, with exclusive content you won't find anywhere else: INSTAGRAM: @LeonTheAlchemist | https://www.instagram.com/leonthealchemist  TWITTER: @AlchemistLeon | https://twitter.com/alchemistleon LINKTREE: https://linktr.ee/leonthealchemist WEBSITE: http://bioalchemy.co COURSE: http://bio.ax/   LEARN Want to take your biohacking skills to the next level? Wake up feeling better each and every day? Or as Dr Aubrey De Grey has suggested, see if you can implement some of the longevity biohacks that may see you living to 1,000 years or more with advancements in technology? Then my intensive biohacking course The Alchemist's Guide to Biohacking (http://bio.ax/) is something you should consider becoming a student of. Use the code "HALF" during the first month of this podcast being launched to get 50% off lifetime access, with all future updates. Check it out at: http://bio.ax/    SUPPORT I spend a ton of time putting together this podcast, and would love your support. Whether as simple as reviewing this podcast, to checking out the products I recommend, or even becoming a student of my intensive biohacking course "The Alchemist's Guide To Biohacking", I appreciate every human who supports me, however large or small the action. ITUNES: https://apple.co/2GQnXH2  SUB ON GOOGLE: https://bit.ly/2SbvJ05  BIOHACKING COURSE: http://bio.ax/

Rand Cameron Jr., Jan Roberts, LCSW, and Jahan Marcu, Ph.D., discuss three main topics:1) The current shaping of NY State marijuana legalization and how it will effect the inclusion of people of color and women.(2) This historical moment in time compared to ending prohibition and the agricultural industry during emancipation proclamation. And (3) the importance of educating the public on the currently known medicinal applications of cannabis so that it is able to remain relevant when competing with the emerging recreational/ adult use market. The word of the day is “Anandamide” the endocannabinoid known as the bliss compound. And the gang plays a round of guessing the fake cannabis news headline at the end of the show. Other topics include recent science in the news such as THC/CBD brewed in yeast, Parrots that are terrorizing poppy fields in India, and some personal stories about the discovery of THC and the Endocannabinoid system. And fishing, we love talking about fishing on the show. See acast.com/privacy for privacy and opt-out information.

Download Key Takeaways Bluebird Botanicals is leading the industry in third-party testing and Lab results, green initiatives and a stand on hemp policy. CBD helps cushion the psychoactive impact of THC on CB1 receptors, making for a less intense ‘high’. Lex has a lot of hope for the 2018 Farm Bill, and believes hemp has widespread uses that will open many market opportunities in the future. Intro Joe interviews Lex Pelger, Science Director of Bluebird Botanicals, a Colorado-based company. They talk about CBD and the issues with the FDA talking about health benefits. The use cases of hemp and drug war are discussed. Who is Lex Pelger? He is a Science Director of Bluebird Botanicals. Lex moves from New York to Colorado. He did a psychedelic storytelling open mic tour (Blue Dot tour) across the USA and it culminated at the MAPS Psychedelic Science Conference. Moved from the hustle of New York to Colorado to have his baby. The Cannabinoid Lex gets excited the more he learns about how intricate the endocannabinoid system is to humans and all mammals Bluebird Botanicals doesn't make any medical claims CDB supports health and homeostasis The cannabinoid system was discovered in the body only 25 years ago Opium and Cannabis were the two oldest plants used in the body There isn't anyone connection for cannabis, because there are so many receptors in the human body There is a ton of research happening on cannabinoids Lex thinks the research ban on phytocannabinoids is unfortunate Cannabis and cannabinoids are the most studied drugs in the US CBD functions as a homeostasis molecule Anandamide was the first endogenous cannabinoid discovered in the human brain in 1991 by a team led by Raphael Mechoulam in Israel Raphael Mechoulam discovered the final structure of THC in 1963 CB1 Receptor in the brain was discovered in 1991 also CB1 Receptor If the CB1 receptors are blocked in a human or animal, they won't get ‘high’ on weed The presence of CBD doesn't allow THC to fully bind to the CB1 receptor, so when CBD is present in THC, you won't get quite as high Lex thinks it's unfortunate that because weed has been in prohibition, it has been bred so hard to only have THC He thinks all weed should have a little bit of CBD to cushion the psychoactive nature of THC The Endocannabinoid System Joe says there is no profile to test the endocannabinoid system to know if a person is deficient or not, that he knows of Lex says if you get your genetic results from a company like 23 and me, it will tell you about your cannabinoid alleles A bad trip to a young brain can damage it forever The activists that annoy Lex are ones that refuse the obvious negatives Weed should not be given to all children The ‘Right to Fly’ Jonathan Thompson - Psychedelic Parenting Blog and Podcast How to create a community on psychedelics Noah Potter - Psychedelic Law Blog An open-source thought experiment in psychedelic law and policy “This plant is tied down by so many regulations” - Lex In the state of Colorado, you can't make new genetics Lousy laws made it hard to diversify the cannabis plant Lex believes Aldous Huxley’s book The Island is the best blueprint for what a sane integration of psychedelics and psychoactive might look like. Lex says people taking mushrooms in the woods together is so special, simply because a group of people is spending 6-8 hours with nature and with each other. Bluebird Botanicals Many different products - isolates, oils, vape juice, and topicals will be back soon Independent Lab Verification Leading the industry with third-party lab results Transparent about ingredients, NO pesticides used! Paired with Eurofins - world’s biggest testing lab Bluebird partners with the farmers, packaging partners, etc to be green and more eco-friendly always CEO Brandon hears about a new point of quality to be added, he goes for it Passed 99% inspection quality, CGMP Lex thinks its so nice to work for a company that focuses on giving back to the customers, focusing on employees, quality, the planet, and just giving back CBD Drug Law Changes in California The regulations restrict being able to add CBD to food, which goes is against the 2014 Federal Farm Bill Bluebird is on the board for the US Hemp Roundtable - Hemp Policy Jonathan Miller - Lawyer of the group and writer to address misinterpretation of the law “It's foolish to have the 1950’s 1960’s mindset of cannabis” - Joe Marijuana vs Hemp Both are cannabis plants Cannabis is the species, THC is more than .3% THC, Hemp is less than .3% THC “If a state inspector comes in and tests 6 samples and the results come up as .4% or .5%, they make you burn it. They don't burn it for you, you have to burn it yourself while you watch.” - Lex Cannabis is tricky to grow for commercial use It takes 3 generations for the plant to get used to the environment “Thank you, farmers, for being farmers” - Joe 2018 Farm Bill Mitch McConnell majority leader of the Senate, is pushing this because he comes from Kentucky, the Hemp state. The Senate version of the Farm Bill is correct, the House version has none of the correct language in it. McConnell and the pro-hemp committee will hash out the differences between the two bills. This Bill expands on all of the rights so it makes it look more enticing and safe for big businesses like Whole Foods and Banks. This bill is going to open up many markets. Hemp as an Industrial Product “What’s really cool about hemp is how widespread the uses are” - Lex The Hemperor, Jack Herer discovered all of the uses for the hemp plant Oil and plastic did win, hemp did not win as a top 10 commodity It’s a hard plant to work within the processing stage Thomas Jefferson stopped growing hemp because the retting stage was too hard on his slaves Hemp is not going to change all the markets it's been said it will transform Lex says hempcrete is fascinating. Using hemp as lubricants, bath bombs, and just the seeds are fascinating uses The Russians and the English fought in a war over access to hemp Hemp is a rope that doesn't get destroyed by saltwater, fueled the world’s Navy Fiber is so important, and hemp as a fiber was widespread Hemp seeds are a perfect mix of essential fatty acids Hemp seed made pigeons breed more Joe says there was a huge tradition of people eating pigeons Agriculture is so bad for topsoil, hemp can help repair our lands for us to keep surviving Hemp is a holy material in Korea Joseph Needham layed out all of China’s inventions and explained that the founders of Daoism had a cannabis-induced ‘dream’ and envisioned the first Daoist school where Yin and Yang came from Lex’s job as a Science Director for Bluebird Lex does a lot of education around CBD, Cannabinoid science conferences His passion for cannabis stems from his grandma’s medical condition He wanted to find a way to describe the cannabinoid system for elders to understand Lex is thankful for groups like Erowid, who sit down and interview our elders Lex tells a story about a man who took LSD in the woods, and fell to the ground and felt one with the trees, felt himself rooting down, and felt complete. He never forgot that feeling Lex thinks that a person should be stable before embarking on a psychedelic journey “Huxley says that therapists are attracted to psychedelics because of their own dark icebergs” - Lex. He thinks that therapists should be A gatekeeper, not THE gatekeeper Joe has been trying to get in touch with Dana Beal who popularized ibogaine “Dana Beal was an old-time, cowboy pot smuggler to fund yippie political activism, outreach, and political activism, so he could make the way that he made money, illegal” - Lex He used the system against itself Cannabis can cause catalepsy in people - which makes one ‘blackout’ 90% of cointel pros were against the Black Panthers Hoover feared them because they were black and he was racist They were extremely effective Lex explains that the war on cannabis has a racist framework, Nixon said “Because black people use cocaine and hippies use cannabis, we can use it against them” Lex goes on to talk about the history of the CIA, which puts its money into drug trade because it's untraceable, they protect the drug lords to use it for their own financial benefit He says the CIA and DEA are inefficient bureaucracies “Our belief at Bluebird, is we have to end the war on drugs. It's not a war on drugs, it's a war on people. The war on drugs is incredibly effective at doing what it was designed to do, and that was to hold, certain people groups down” Joe comments saying that there are babies being born and being brought into this world. He appreciates Bluebird for having proper business practice Final Thoughts Lex finished his Moby Dick Pot books about the endocannabinoid system and the war on drugs He says he based them on Moby Dick because it was the only thing large enough to fit the entire history of cannabis and war on drugs He does the Greener Grass Podcast for Bluebird which includes topics on cannabis and green initiatives. He is also a part of the Psychedelic Salon http://www.lexpelger.com/ https://bluebirdbotanicals.com/

Lex Pelger is the host of Psymposia. He’s also a drug writer and scientist based in Brooklyn. His current project, Anandamide or: the Cannabinoid is a graphic novel about cannabis based on Moby Dick. He graduated from Boston University with a BS in Biochemistry and Molecular Biology.

On Episode 5 of Anslinger: The untold cannabis conspiracy, we investigate the medical and therapeutic uses of cannabis. We also continue our conversation with Dr. Pritesh Kumar about differences between endocannabinoid and opioid systems in the human body, and their physiological actions.

Ivor Cummins is a Biochemical Engineer who in 2012 was disturbed by a set of his own abnormal blood test results. Consultation with multiple doctors yielded little insight into the cause of his elevated cholesterol, ferritin and GGT so he turned to his analytical roots to study the problem. In the process, he evaluated hundreds of scientific papers, ultimately concluding that that flawed hypotheses and a breach of the scientific method have resulted in the current “diabesity” epidemic. Ivor is here today with Dr. Tommy Wood talking on topics related to his well-referenced new book, Eat Rich, Live Long: Mastering the Low-Carb & Keto Spectrum for Weight Loss and Great Health. They also discuss the trouble with polyunsaturated oils, advice on fat loss for the insulin sensitive, and the best test for cardiovascular disease risk (hint: it’s not LDL). If you enjoy this podcast, Ivor is a regular presenter at low-carb/keto events and maintains an active blog and social media presence. Here’s the outline of this interview with Ivor Cummins: [00:00:17] Keto Summit, Dave Feldman. [00:00:48] Boundless Health Podcast with Dr. Bret Scher. [00:01:57] Podcast: The True Root Causes of Cardiovascular Disease, with Dr. Jeffry Gerber. [00:02:15] Book: Eat Rich, Live Long: Mastering the Low-Carb & Keto Spectrum for Weight Loss and Great Health, by Ivor Cummins and Jeffry Gerber, MD. [00:02:29] Videos: here and here. [00:03:20] Insulin, IGF-1, acellular carbs. [00:03:56] Sunlight exposure, 25-OH-D video. [00:04:37] Minerals, Study: DiNicolantonio, James J., James H. O’Keefe, and William Wilson. "Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis." Open Heart 5.1 (2018): e000668. [00:05:28] Gabor Erdosi, Lower Insulin Facebook Group. [00:05:43] Video: Roads to Ruin? from Physicians for Ancestral Health 2017 conference. [00:06:01] Guðmundur Jóhannsson, gut health; Podcast: Foodloose Iceland. [00:07:40] Study: Schwalfenberg, Gerry K., and Stephen J. Genuis. "The importance of magnesium in clinical healthcare." Scientifica 2017 (2017). [00:08:10] Industrial seed oils. [00:09:05] Unilever sells its margarine business. [00:10:17] Studies: Alvheim, Anita Røyneberg, et al. "Dietary Linoleic Acid Elevates the Endocannabinoids 2‐AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet." Lipids 49.1 (2014): 59-69. And: Alvheim, Anita R., et al. "Dietary Linoleic Acid Elevates Endogenous 2‐AG and Anandamide and Induces Obesity." Obesity 20.10 (2012): 1984-1994. [00:10:48] Studies: Nanji, Amin A., and Samuel W. French. "Dietary factors and alcoholic cirrhosis." Alcoholism: Clinical and Experimental Research 10.3 (1986): 271-273. And: Kirpich, Irina A., et al. "Alcoholic liver disease: update on the role of dietary fat." Biomolecules 6.1 (2016): 1. [00:12:09] Book: Deep Nutrition: Why Your Genes Need Traditional Food, by Cate Shanahan, M.D. [00:12:45] Studies: 1. Ramsden, Christopher E., et al. "The Sydney Diet Heart Study: a randomised controlled trial of linoleic acid for secondary prevention of coronary heart disease and death." The FASEB Journal 27.1 Supplement (2013): 127-4. 2. Frantz, Ivan D., et al. "Test of effect of lipid lowering by diet on cardiovascular risk. The Minnesota Coronary Survey." Arteriosclerosis, Thrombosis, and Vascular Biology 9.1 (1989): 129-135. 3. Strandberg, Timo E., et al. "Mortality in participants and non-participants of a multifactorial prevention study of cardiovascular diseases: a 28 year follow up of the Helsinki Businessmen Study." Heart 74.4 (1995): 449-454. 4. Rose, G. A., W. B. Thomson, and R. T. Williams. "Corn oil in treatment of ischaemic heart disease." British medical journal 1.5449 (1965): 1531. [00:13:47] Study: Hooper, Lee, et al. "Reduction in saturated fat intake for cardiovascular disease." The Cochrane Library (2015). [00:15:28] Study: Ip, Clement, Christopher A. Carter, and Margot M. Ip. "Requirement of essential fatty acid for mammary tumorigenesis in the rat." Cancer Research 45.5 (1985): 1997-2001. [00:16:28] Study: Pearce, Morton Lee, and Seymour Dayton. "Incidence of cancer in men on a diet high in polyunsaturated fat." The Lancet 297.7697 (1971): 464-467. [00:16:56] Breast milk composition is now almost 50% PUFA. [00:17:50] David Bobbett. [00:19:59] Book structure. [00:20:51] Fat-loss for the insulin sensitive. [00:21:10] Videos: Jeff Gerber interviews Simon Saunders and Marty Kendall. [00:23:03] Ghrelin. [00:24:21] Protein and lean body mass. [00:26:05] Glucagon, mTOR. [00:26:22] Ron Rosedale. [00:26:34] Valter Longo. [00:27:02] IGF-1 U-shaped curve. [00:28:06] Study: Levine, Morgan E., et al. "Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population." Cell metabolism 19.3 (2014): 407-417. [00:28:49] Book: Protein Power: The High-Protein/Low Carbohydrate Way to Lose Weight, Feel Fit, and Boost Your Health - in Just Weeks! By Michael Eades and Mary Dan Eades. [00:30:39] Study: Levine, Morgan E., et al. "Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population." Cell metabolism 19.3 (2014): 407-417. [00:31:06] NHANES. [00:31:18] Study: Cohen, Evan, et al. "Statistical review of US macronutrient consumption data, 1965–2011: Americans have been following dietary guidelines, coincident with the rise in obesity." Nutrition 31.5 (2015): 727-732. [00:32:20] Kitavans. [00:34:05] Hyperlipid and Denise Minger. [00:36:37] Icelandic diets for longevity [00:39:07] Cardiovascular disease. [00:39:35] Basic lipid panel. [00:39:45] Study: Castelli, William P. "Lipids, risk factors and ischaemic heart disease." Atherosclerosis 124 (1996): S1-S9. [00:40:24] Ratios. [00:41:54] Study: Johnson, Kevin M., David A. Dowe, and James A. Brink. "Traditional clinical risk assessment tools do not accurately predict coronary atherosclerotic plaque burden: a CT angiography study." American Journal of Roentgenology 192.1 (2009): 235-243. Commentary: Ware, William R. "The mainstream hypothesis that LDL cholesterol drives atherosclerosis may have been falsified by non-invasive imaging of coronary artery plaque burden and progression." Medical hypotheses 73.4 (2009): 596-600. [00:42:30] Familial Hypercholesterolemia and CVD. [00:43:27] cholesterolcode.com, remnant cholesterol, Plasma Atherogenic Index. [00:44:36] Podcast: Health Outcome-Based Optimal Reference Ranges for Cholesterol [00:46:06] Coronary calcium scan. [00:46:25] Study: Nasir, Khurram, et al. "Interplay of Coronary Artery Calcification and Traditional Risk Factors for the Prediction of All-Cause Mortality in Asymptomatic Individuals Clinical Perspective." Circulation: Cardiovascular Imaging 5.4 (2012): 467-473. [00:47:54] Longitudinal score. [00:49:41] Plaque density. [00:50:11] Interview with Matt Budoff. [00:52:37] Video: Dr. Eades at Low Carb Breckenridge, Agatston score. [00:54:38] The Fat Emperor. [00:54:53] Low-carb Breckenridge 2018. [00:55:10] Ketofest, Keto Con, Low-carb USA, Refind Health. [00:55:45] Widowmaker movie.

(0-5 minutes) Eric introduces himself and explains his current passion which is mindful improv. He teaches groups of people how to respond mindfully to social situations. He explains some exercises that he uses at the beginning of class. He talks about how he helps beginners get through initial blocks and past their fears of opening up in front of an audience. Stewart then brings up his experience as a beginner in Salsa and how when we begin anything we are only aware of a small fraction of the stimuli that is being presented to us. After we start to improve whole new layers of awareness open up. (5-10 minutes) Eric explains how he views teaching and how its really important to impart to new students only one thing about what they are learning. He has people focus on their emotional experience. Whether they are fearful or excited? This brings people into how they are feeling now. He says that mindful improv is about helping people develop a practice of it not only in the class itself but in their lives as well. Stewart brings up how this is one of the most important parts of a meditation practice as well: to bring the practice into daily life. Eric explains how he has been practicing disciplined mindfulness practices for several years now and has taken notes. He shows how no matter how much we practice some things just continuously come up and we have to learn how to deal with these issues and not wish them away. We talk about how Eric doesn't really have a formal practice and that he really tries to bring the practice into daily life. He mentions that many friends of his try to convert him into a formal meditation practice. From Eric's perspective, he is already aware, at least a little bit, in everyday life. Awareness is always present so its a better practice to just heighten that awareness in everyday life as opposed to setting off a time where we do it. (10-15 minutes) Stewart mentions how historically he would have disagreed with Eric about the necessity of having a daily formal sitting meditation practice, but how over the last couple years he has started to see it differently. Any technique is just a crutch that makes the conditions more favorable to drop into a meditative state. The meditative state is what we are looking to engender, not the technique. Humans have a way of turning positives experiences into stable beliefs, but these beliefs are not accurate indicators of reality. Eric mentions that culture itself is a byproduct of these stable beliefs. He explains the process of ego development in a young child. The infant starts off as just pure consciousness. There is no separation between the baby and its environment. The baby just is. As it starts to develop, the baby takes on communication with the family and starts to develop a sense of self. The baby starts to develop likes and dislikes. At some point, the individual then becomes conscious of this conditioning and they have an opportunity to make a shift to say "Oh now I'm an individual and I am on my own". In reality its difficult to do this because the process of the individual's relationship to the environment continues. We are always conditioned to the environment around us. There is no separate self. Eric goes on to explain how formal sitting practice might be helpful for someone who has a 9-5 job and needs a sense of structure to their practice to make it stick. Eric doesn't have this life. He talks about how his schedule is very erratic. Stewart mentions that he often finds himself in a state of friction and that its difficult to remember in those times that those times are necessary for the creative times. Eric mentions the cult of working hard that is endemic in the startup world. He believes that this type of deification of work is unnecessary. He mentions that most work and conversation are worthless and busywork. (15-20 minutes) Eric mentions the importance of being clear from the outset as to what the people working on a task are doing. He says that many of his friends are working long hours in something that they supposedly like, but then end up totally drained at the end of the week. He talks about how work environments lead to people stealing energy from each other. He mentions that with his company Mindful Improv, he teaches people how to share energy with each other which leads to lots of exponential benefits. We drastically switch topics to how Eric uses marijuana to improve his meditation practice. He says that it helps him to do problem-solving and increases his sensitivity. He talks about his personality and how he tends to always be in problem-solving mode. He says other people used to tell him that he overanalyzes anything and he agrees, but at the same time, it is a gift as well. Weed helps him tap into this more frequently. (20-25 minutes) Stewart asks Eric whether he has any negative aspects of his marijuana use. He says that after intense analyzation and note taking he can't find any real drawbacks to its use. Sometimes he has to police his use and he checks in to see whether it is a problem, but he hasn't been able to find any. Stewart explains about the endocannabinoid system and how its the oldest system in the body. It reacts directly with cannabinoids or cannabis. An Israeli researcher found something called Anandamide when researching cannabis and named it after Ananda, or the unconditional bliss that arises once you tap into a meditative state. Anandamide naturally occurs in the body, but if the endocannabinoid system doesn't produce it naturally due to trauma or other conditions, the body can react favorably to cannabis. Stewart talks about plant medicines and how they make it clear that we are not separate selves and we are in a constant relationship with the outside environment. Eric brings up how the cells in our body are constantly changing. We bring it back to Mindful improv and how relationship is really important and maybe one of the most important places to bring mindfulness into. Conversation is not a real thing. They are symbols of reality. They are not reality itself. Language is a construct that humans created. Eric explains how his sense of self developed. He never felt like he fit in with the kids at school. He never liked the noise. Kids usually create an identity for you. This leads to a sense of self and kids who are bullied usually need to develop a protective shell by becoming what they think they are as opposed to what the other kids say. 25-30 minutes Eric talks about how the ego develops and how we find ourselves in romantic relationships with people who fall in love with the false ego we have created. Then when the partner starts to change from the thing that we fall in love with, we fall out of love with them because they aren't the person we fell in love with. Stewart brings up how the sense of self is changing just like everything else, as much Buddhist wisdom points to. Everything is impermanent. Eric brings up the fact that many humans are tied to an emotional connection with people and people are balls of emotional baggage. It's important to be careful with those we choose to be an emotional connection with because everyone has stuff going on beneath the surface. Stewart starts to tell his story of how he created his sense of self as an overweight nice kid who people liked, but was a bit of a loner and awkward. At the age of 19, he started smoking cannabis and his diet changed radically. Eric says "shouldn't you have eaten more because of the munchies". Stewart explains how he started to change his diet based on the input of cannabis. After Stewart lost the weight people treated him very differently. (30-35 minutes) Eric also has a similar story but with different storylines. He was thin and people treated him that way. He brings up the idea that its hard to tell what other people see when they look at us. Stewart asks about Eric's practice and whether he has any practices that have to do with the breath. He says that anxiety is excitement without the breath and that for much of his life he hasn't been breathing. He explains that he moved to San Diego and he took four months to just focus on breathing, weightlifting, yoga, and eating. He gained 16 pounds of muscle which went away right after he changed his diet. He tapped into a different way of breathing underneath the anxious breath. Weightlifting and yoga taught him how to find this deeper breath. He found this breath quite liberating because he decided to take this time after getting tired of constantly over analyzing everything. He could take all the energy of trying to analyze everything and just focus on being here now. Stewart asks Eric whether he has any practices currently. Eric explains how he is now done with a five-year challenge where he moved to a new place every 6 months and practiced creating a new version of himself. He would meet totally new people and developed a new sense of self based on these new relationships with other people. Stewart explains his own experience living in new countries for a year at a time and then came back to integrate it and then repeat in a new country. This experience allowed him to form a new more confident self who wasn't trapped by the boxes that other people placed him in. He became more confident and ready to take on challenges. The most difficult thing about this is coming back to family and having a total reversal of all this to come back and play the old family dynamics. (35-40 minutes) Eric explains how Boulder is great for him because he has a fast paced mind and Boulder is slowed. He can't live in fast-paced places because it's too intense. He had a moment in New York where he realized that he isn't even there when he is there. He says New York is a place of human doing, not of human beings. He says that in Boulder people are ok with just being. Stewart asks Eric about the most important thing going on in his life right now. Eric says that a wise friend once told him that there are three phases in your life that you must go through. Number 1 is to figure out who you are. Number 2 is to figure out where you want to be. Number 3 is who you want to come along. Stewart asks Eric about the balance between chaos and rigidity and how he deals with it. Eric says that mindful improv brings a lot of chaos into that. The ego creates rigidity. If you have a strong ego it makes it difficult to adapt to change. This applies to companies as well. He brings up that humans are the most adaptable species on earth. Stewart brings up a theory from "Sapiens" about how grains and other vegetables used humans to make themselves more widespread.

What’s important to recognize is that the kind of blanket statement of either pot is good for you or it’s bad for you is really oversimplified and I hope we can break some of that down and really talk about the intricacy of that today. Disclosure: The purpose of this podcast is to dispel dogma, share scientific backed information, and talk about the health benefits of cannabis Any statement mentioned in this podcast is not a medical recommendation so please speak to your physician before doing anything stupid. About the Guest David Krantz: David Krantz is an epigenetic coach, musician, and entrepreneur based in Asheville, North Carolina. He serves as the Director of Psychoacoustics at the Apeiron Center for Human Potential, where he explores the interaction between art, science, and health. As a coach, he works with clients using genetically informed, personalized strategies for optimal wellness and greater creativity. The Topic: Cannabis Genetics Cannabis is a controversial topic. To some, it is a gateway drug. To others, it helps deal with common problems including inflammation, epilepsy, and multiple sclerosis. In this podcast, David and Boomer speak in depth about the endocannabinoid system, cannabinoids, cannabis genetics, and how your genes may affect both your desire to use weed and the overall effect it has on you. Key Highlights: Addressing the age-old question: is marijuana good for you? What is the difference between CBD and THC? What is Sativa versus Indica? The potential use of cannabis in PTSD The natural occurring cannabinoids in our body Why higher levels of anandamide may be associated with increased stress resiliency The gene associated with the breakdown of anandamide into arachidonic acid How CNR1, one of our main cannabinoid receptor genes, is involved in bone density, constipation, weight gain, weight loss, circadian rhythm, hormone regulation, cognitive function and also leaky gut What genes and variants are associated with cannabis consumption and a worse working memory Scientific Studies on Cannabis Genetics: How CYP2C9 affects the metabolism of THC - Interindividual variation in the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) as related to genetic polymorphisms in CYP2C9 The impact of cannabis consumption on working memory depending on CNR1 gene variant - Functional genetic variation of the cannabinoid receptor 1 and cannabis use interact on prefrontal connectivity and related working memory behavior. Withdrawl Symptoms and the FAAH gene - Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. Amygdala and Hippocampus sizes among Cannabis Users - Associations between cannabinoid receptor-1 (CNR1) variation and hippocampus and amygdala volumes in heavy cannabis users. ATK1 and the Psychedelic Effects of Marijuana - Associations between cannabinoid receptor-1 (CNR1) variation and hippocampus and amygdala volumes in heavy cannabis users. Let's say you want to look into the potential impact of cannabis on your health. You can start by looking at your cannabis genetics. If you already have 23andMe, below is a guide to learning more about your genetic predispositions for cannabis. If you want to learn more about genetic testing and its use for creating custom health plans, schedule a FREE 30-minute call today. How to Access Your 23andMe Raw Data: The raw data in each 23andMe report contains over ~600,000 lines of raw data. Log-in to 23andMe.com Access the raw data. The menu bar contains a header “Tools.” Move your cursor over the Tools header to access the drop-down menu. The last of the six drop-down features is “Browse Raw Data.” Click on this. This is the most powerful area of 23andMe. From this point, you can access ~600,000 lines of genetic information with the RSID. Finding the RSID. 23andMe requires you to search raw data through RSID. The RSID is the Reference SNP cluster ID. Researchers use it to report findings. How to Look Into Your Own Cannabis Genetics: The below single nucleotide polymorphisms are searchable in 23andMe using the RSID listed below. CYP2C9 – the liver enzyme which breaks down THC RSID – RS1057910 A allele = fast metabolizer of THC CC allele = slow metabolizer of THC CC tends to take longer to process THC, hence more in the bloodstream CC also tends to report more drowsiness or a more intense effect from the same amount of THC FAAH - Breaks down Anandamide, one of your body's two main cannabinoids. Activates the CB1 receptor. RSID - RS324420 C allele - lower levels of anandamide (more FAAH activity) CC - more dopamine activation when exposed to the smell of cannabis CC - worse sleep with cannabis use CNR1 - is the Cannabinoid Receptor 1 gene. This gene is in the brain and central nervous system. It is involved in our experience with anxiety, feeding behavior, and neurotransmitter balance. RSID - Rs2023239 G allele - associated with more cravings and withdrawal The correlation is very strong when combined with a FAAH CC variant G allele carriers may have worse working memory than AA when using cannabis ATK1 - Protein which acts as signaling for the dopamine pathway RSID - Rs2494732 C allele associated with a more psychedelic effect Additional Resources for Cannabis Genetics: David Krantz's website David Krantz's free webinar on cannabis genetics David's article on the CYP2C9 gene Professor of Pot - an informed resource on cannabis See acast.com/privacy for privacy and opt-out information.

13: Happiness: "The True Driver Of Success?" Wait What?  I Thought It was Anger!   In this show our hosts Dave Frees and Somnath Sikdar (Alex is away) examine why happiness matters and has to be balanced with Anger and a true driver of success.  There are over 20 happiness hacks and strategies that have some level of science to back them up.   https://www.facebook.com/intopform/videos/340175963046804/   Key Words:  Happiness, happiness hacks, strategies of happiness,   Want to attend the Business Black Ops Live event? http://www.3DaysToSuccess.com or call Lisa at 610-933-8069   What You’ll Learn In This Show:   The placebo effect and happiness Dave’s experience with the Dali Lama and happiness, shakti, and telling his holiness a joke. Understanding: Happiness, gratitude, resilience, love, compassion...and desired/interrelated states, how they are created and how to have more of these states. Resources: Psychology Today blog:  The Neurochemistry of Happiness, The Hormones of Happiness, The Greater Good From Berkley University. The science of happiness. https://www.psychologytoday.com/blog/the-athletes-way/201211/the-neurochemicals-happiness  Chris Bergland, http://www.indiatimes.com/health/healthyliving/the-hormones-of-happiness-and-how-to-increase-them-242282.html, http://greatergood.berkeley.edu/article/item/how_to_trick_your_brain_for_happiness There are four major chemicals in the brain that influence our happiness, create better states by designing your experiences to improve your mental chemistry and states. (DOSE): Dopamine Ways to increase your dopamine levels: • Set daily or monthly goals, since they give you something to strive towards. • Set exercise goals, since dopamine increases in tandem with serotonin and endorphins when you exercise. Setting goals will increase the production of dopamine even more.• Eat foods that are rich in protein.• Set exercise goals, since dopamine increases in tandem with serotonin and endorphins when you exercise. Setting goals will increase the production of dopamine even more.• Eat foods that are rich in protein. Oxytocin Ways to increase your oxytocin levels: • Get a massage, since it relaxes your muscles and the prolonged physical contact triggers the release of oxytocin. Show your friends and family that you love them by touching them affectionately. You can hug your parents, throw an arm around a friend or cuddle up with your partner.   Serotonin Ways to increase your serotonin levels: Spend time in the sun, since sunlight causes your body to produce Vitamin D, which triggers the release of serotonin. • Think happy thoughts, since your brain produces serotonin when you remember happy memories or think about things that make you happy. Consume foods like milk and corn, since they contain tryptophan, a substance that your body converts to serotonin. Other carbohydrates also contain tryptophan. Do a low-intensity workout, since your body produces serotonin when it is performing aerobic exercise, as opposed to the endorphins it produces during anaerobic exercise.     Endorphins. - Ways to increase your endorphin levels: • Exercise to cope with chronic pain.• Eat spicy food, since your tongue has receptors that react to spice by sending messages to your brain that are similar to pain signals, causing your brain to trigger the release of endorphins.   Endocannabinoids: “The Bliss Molecule” Endocannabinoids are self-produced cannabis that work on the CB-1 and CB-2 receptors of the cannabinoid system. Anandamide (from the Sanskrit “Ananda” meaning Bliss) is the most well known endocannabinoid. Interestingly, at least 85 different cannabinoids have been isolated from the Cannabis plant. The assumption is that each of these acts like a key that slips into a different lock of the cannabinoid system and alters perceptions and states of consciousness in various ways. It is likely that we self-produce just as many variations of endocannabinoids, but it will take neuroscientists decades to isolate them. Dopamine: “The Reward Molecule” Dopamine is responsible for reward-driven behavior and pleasure seeking. Every type of reward seeking behavior that has been studied increases the level of dopamine transmission in the brain. If you want to get a hit of dopamine, set a goal and achieve it.   Oxytocin: “The Bonding Molecule” Oxytocin is a hormone directly linked to human bonding and increasing trust and loyalty.  In some studies, high levels of oxytocin have been correlated with romantic attachment. Some studies show if a couple is separated for a long period of time, the lack of physical contact reduces oxytocin and drives the feeling of longing to bond with that person again. But there is some debate as to whether oxytocin has the same effect on men as it does on women. In men, vasopressin (a close cousin to oxytocin) may actually be the “bonding molecule.” But again, the bottom line is that skin-to-skin contact, affection, love making and intimacy are key to feeling happy.   In a cyber world, where we are often ‘alone together’ on our digital devices, it is more important than ever to maintain face-to-face intimate human bonds and ‘tribal’ connections within your community. Working out at a gym, in a group environment or having a jogging buddy is a great way to sustain these human bonds and release oxytocin.   In a 2003 study, oxytocin levels rose in both the dog and the owner after time spent ‘cuddling’. The strong emotional bonding between humans and dogs may have a biological basis in oxytocin. If you don’t have another human being to offer you affection and increase oxytocin your favorite pet can also do the trick.   Endorphin: “The Pain-Killing Molecule” The name Endorphin translates into “self-produced morphine."  Endorphins resemble opiates in their chemical structure and have analgesic properties. Endorphins are produced by the pituitary gland and the hypothalamus during strenuous physical exertion, sexual intercourse and orgasm. Make these pursuits a part of your regular life to keep the endorphins pumping.   Endorphins are linked less to ‘Runner’s High’ now than endocannabinoids, but are connected to the ‘feeling no pain’ aspect of aerobic exercise and are produced in larger quantities during high intensity ‘anaerobic’ cardio and strength training.   In 1999, clinical researchers reported that inserting acupuncture needles into specific body points triggers the production of endorphins. In another study, higher levels of endorphins were found in cerebrospinal fluid after patients underwent acupuncture.  Acupuncture is a terrific way to stimulate the release of endorphins.   GABA: “The Anti-Anxiety Molecule” GABA is an inhibitory molecule that slows down the firing of neurons and creates a sense of calmness. You can increase GABA naturally by practicing yoga, meditation or “The Relaxation Response.”  Benzodiazepines (Such as Valium and Xanax) are sedatives that work as anti-anxiety medication by increasing GABA. These drugs have many side effects and risks of dependency but are still widely prescribed. A study from the "Journal of Alternative and Complementary Medicine" found a 27% increase in GABA levels among yoga practitioners after a 60-minute yoga session when compared against participants who read a book for 60 minutes. The study suggests yoga might increase GABA levels naturally.   Serotonin: “The Confidence Molecule” Serotonin plays so many different roles in our bodies that it is really tough to tag it. For the sake of practical application I call it “The Confidence Molecule.” Ultimately the link between higher serotonin and a lack of rejection sensitivity allows people to put themselves in situations that will bolster self-esteem, increase feelings of worthiness and create a sense of belonging. To increase serotonin, challenge yourself regularly and pursue things that reinforce a sense of purpose, meaning and accomplishment.  Being able to say "I did it!" will produce a feedback loop that will reinforce behaviors that build self esteem and make you less insecure and create an upward spiral of more and more serotonin.   A variety of popular anti-depressants are called Serotonin-Specific Reuptake Inhibitors (SSRIs) — these are well known drugs like Prozac, Celexa, Lexapro, Zoloft, etc. The main indication for SSRIs is clinical depression, but SSRIs are frequently prescribed for anxiety, panic disorders, obsessive compulsive disorder (OCD), eating disorders, chronic pain, and post-traumatic stress disorder (PTSD).   Adrenaline: “The Energy Molecule” Adrenaline, technically known as epinephrine, plays a large role in the fight or flight mechanism. The release of epinephrine is exhilarating and creates a surge in energy. Adrenaline causes an increase in heart rate, blood pressure, and works by causing less important blood vessels to constrict and increasing blood flow to larger muscles. An “Epi-Pen” is a shot of epinephrine used in the treatment of acute allergic reactions.   An ‘adrenaline rush’ comes in times of distress or facing fearful situations. It can be triggered on demand by doing things that terrify you or being thrust into a situation that feels dangerous. You can also create an adrenaline rush by taking short rapid breathes and contracting muscles. This jolt can be healthy in small doses, especially when you need a pick me up.   25 Happiness Hacks:   http://www.cnn.com/2016/01/22/health/happiness-hacks/   Turn on a light box DMF: Verilux Light therapy is an effective treatment for seasonal affective disorder (SAD), but experts agree that it works to treat symptoms of major depressive disorder as well. Feeling blue? You can turn on a light box for 30 minutes to an hour   Open the shades and close them (SLEEPMASK) DMF If you don't have access to a light box, the simple act of letting in some sunlight can brighten your mood. When your workspace or living area is brighter, you tend to feel happier too. Go outside Starting to feel down? Head outside to soak up some sunshine. The human body produces vitamin D when exposed to the sun's rays, and research suggests that people who are deficient in the vitamin are more likely to be depressed, anxious, and tired. Step into the sunshine for 20 to 25 minutes of sunlight to lighten your mood naturally. Try meditation DMF: Guided meditation, mantra meditation Mindfulness breathing Headspace and calm Good news: Meditation is a proven stress-buster with no harmful side effects. Studies have shown that its benefits range from pain reduction and lower blood pressure to a boost in libido. Best part? It releases "happy" chemicals in the brain—serotonin, dopamine, and endorphins—all of which work together to put you in a better mood. If you don't know where to start, try a guided meditation to de-stress or start your morning.   Smell the oranges DMF essential oils Citrus scents, such as orange, lemon, and grapefruit bring out positive chemical reactions in your brain as well as work to ease stress. If you want to feel uplifted, use a few drops of citrus essential oil on your pressure points. You can also mix the scent with a floral aroma such as jasmine to increase the positive effects.   Eat carbs as an afternoon snack You know that afternoon mood slump that hits at just the worst time? Well, it turns out that you can eat your way to a happier, more energized afternoon—carbs. For years we've been hearing that we should avoid carbs, but in reality, a low-carb diet can make us feel sad and stressed. Carbohydrates actually boost mood-boosting chemicals in the brain. But let's get something straight here—we want to focus on healthy, whole-grain sources instead of refined carbohydrates to reap the benefits. When you begin to feel down, go for an afternoon snack of 25 to 30 grams of carbs, such as a three-quarter-cup serving of Cheerios.   Play with your pet Having a dog or cat can seriously improve your quality of life—their excitement in seeing you come home and their unyielding loyalty make them great companions. There are a host of reasons why pets improve your health, but they can turn around a bad mood and make you happier in no time. A study found that petting a dog for only 15 minutes releases serotonin, prolactin, and oxytocin—all of which are mood-enhancing hormones, while lowering the stress hormone cortisol.   Take microbreaks Research shows that people who take quick breaks during their workday to watch funny videos online get a high emotional payoff and report feeling more energetic and happy with fewer negative emotions. Not only will this improve your mental health overall; this is an easy way to turn around a bad mood in less than a minute—plus, you can get a metabolism boost, too!   Add turmeric to your meal The active compound in turmeric, curcumin, has natural antidepressant qualities. You may already be adding turmeric to your meals because of its vast whole-body health benefits, such as lessening the effects of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions, as well as fighting Alzheimer's disease and diabetes. Animal studies have also linked curcumin to an increase in serotonin and dopamine, so it's a powerful way to boost your mood.   Listen to music... Have you ever heard a song over the radio that just felt good? Or have you turned on an old CD only to find a flood of happy memories come streaming back? Well, that's due to the fact that music is a mood-booster. It releases the feel-good chemical dopamine into your system and brings on nostalgia.   ...And sing along You can also get happy by making your own music—by singing. University of Manchester researchers discovered that a tiny organ in the inner ear (called the sacculus) is connected to a part of your brain that registers pleasure. The sacculus registers frequency notes that are associated with singing almost instantly, giving you a warm and fuzzy feeling. So go ahead and sing in the shower, belt it out in your car, or get up on that karaoke stage.   Eat chocolate (yes!) While you might not need another excuse to eat more chocolate, here's another: It makes us happier. Chocolate contains tryptophan, which boosts the production of serotonin in the brain, leading to better moods. This trick also works with other foods containing tryptophan, such as poultry and eggs.   Drink coffee This morning energy boost doubles as a mood pick-me-up. A Harvard University study found that women who drank at least two cups of coffee regularly were at a 15% lower risk of depression than women who did not. Just keep in mind that those fancy coffee drinks can have tons of hidden sugar and calories, so it's best to stick with black coffee (and some skim milk).   Sip on some green tea Green tea already boasts an impressive résumé of health benefits. Thanks to the polyphenols it contains, green tea helps with weight loss by boosting metabolism, as well as providing a reduced risk of heart disease, high blood pressure, certain cancers, and osteoporosis. But for your mood? Green tea has been shown to reduce stress levels. A study found that people who drank five or more cups of green tea per day had a 20% lower level of stress than those who drank less than one.   Make a human connection Put down your smartphone and take a step back from your computer screen. If you want to feel better—and fast—go to a friend or family member for some relief. A study from the University of North Carolina at Chapel Hill found that human touch releases those feel-good chemicals like serotonin, as well as reduces blood pressure and heart rate making you feel more relaxed.   Consume healthy fats You know how avocados are some of the most pleasurable foods to eat, with their rich taste and smooth, decadent texture? That's a mood-booster on its own, but research also suggests that their fat content is also the reason why they better our mood. Because fat slows digestion, it evens our blood sugar levels leaving us to feel calm and satisfied. So go ahead and treat yourself to some avocado or nuts next time you're feeling anxious.   Eat more salmon Fatty fish like salmon is high in omega-3 fatty acids, which can help stave off depression (omega-3s are also present in avocados and nuts, as well as grass-fed beef and chicken). This is because they help to maintain brain function in the areas that regulate mood and emotion—a study found that women who hate fish two times per week had a 25% lower risk of depression than women who ate it less often. If you don't like to eat fish, try taking omega-3 fish oil supplements instead.   Try St. John's wort WARNING! This herbal supplement is one of the most-studied herbal supplements for depression, and research shows that it may be as beneficial as antidepressants when treating mild depression. While it may seem like a no-brainer, St. John's wort has known serious drug interactions, including reducing the effectiveness of birth control. Additionally, when taken in conjunction with antidepressants, the supplement can create too-high levels of serotonin, which can lead to heart problems. So before you try this one, be sure to check in with your doctor.      

In this episode, Jonathan talks with his dear friend Lex Pelger. Lex is a co-Founder (along with past podcast guest Brett Greene) of the psychedelic media group Psymposia, an author, and the new host of the legendary psychedelic podcast The Psychedelic Salon. Lex has recently begun publishing his magnum opus, Anandamide, or: The Canabinoid, a graphic novel about cannabis, the war on weed, and our own endocannabinoid system, based on Moby Dick . He is also co-hosting a cross-country tour of Psymposia's popular Psychedelic Storytelling events, called The Blue Dot Tour, with a goal of building psychedelic community in "blue cities inside red states" Full Program notes can be found at:  http://www.psychedelicparenting.org/psychedelic-parenting-podcast-33/

Download Psymposia's MC and Host, Lex Pelger, joins us again on Psychedelics Today to talk about Psymposia's upcoming Blue Dot Tour. Lex also talks about his graphic novel about cannabis, the endocannabinoid system, and the War on Weed. What is the Blue Dot Tour? (From Psymposia.com) The Blue-Dot Tour is our two-month open-mic Psychedelic Stories road trip across the continent starting on the way to the Psymposia Stage Psychedelic Science 2017 in Oakland. Our goal is to hit blue cities in red states that serve as such pressure cookers of activism, education, and art. But also blue cities in blue states, red towns in red states, purple villages in green states, and anywhere we can find a host from Mexico to Canada. We’ll also be screening Robert Barnhart's excellent film 'A New Understanding - the Science of Psilocybin.' Blue Dot Tour Dates (Subject to Change) For the most up-to-date schedule check out the schedule at Psymposia.com  4/06  Boston, MA 4/07 Philadelphia, PA 4/08 Lancaster, PA 4/09 Baltimore, MD 4/11 Athens, GA 4/13 Austin, TX 4/15 Boulder, CO 4/21-23 Psychedelic Science 4/26 Los Angeles, CA 4/27 San Diego, CA Don't see your city on the tour schedule? Reach out to Psymposia to host them in your town/city for an event: hi@psymposia.com Show Notes/Links Lex's Book: Anandamide; or, the Cannabinoid: The CROWN - Volume 1: How to Shoot an Elephant Anandamide; or, the Cannabinoid: Chapter 37: SUNset What is Anandamide? Cannabis, Sleep, & Oleamide lexpelger.com Psymposia Blue Dot Tour Oprah and MDMA creating holes in the brain Oprah, PTSD, & MDMA Therapy CBD for bone health CBDs & Cytochromes P450 Sci-Hub: Public access to research papers Reddit Dark Web  About Lex Pelger: Lex is Host of Psymposia. He's also a drug writer and scientist based in Brooklyn. His current project, Anandamide or: the Cannabinoid a graphic novel about cannabis (based on Moby Dick), illustrates the beauties of the endocannabinoid system (the Whale), the brutalities of the racist War on Weed (Ahab), and the staggering benefits of medical marijuana to ease the aging of our grandparents He graduated from Boston University with a BS in Biochemistry and Molecular Biology

Listen on iTunes: goo.gl/sMnEa0 Listen on Stitcher: www.stitcher.com/podcast/future   Jamie Wheal is Executive Director of Flow Genome Project which he heads up alongside Steven Kotler, who you might know from books such as The Rise of Superman and Abundance, co-written with Peter Diamandis. Jamie is a leading expert on the neuro-physiology of human performance. His work ranges from Fortune 500 companies like Cisco, Google, and Nike, to the U.S. Naval War College and Red Bull. He combines a background in expeditionary leadership, wilderness medicine and surf rescue, with over a decade advising high-growth companies on strategy, execution and leadership. He speaks to diverse and high-performing communities such as Young Presidents’ Organization (YPO), Summit Series, and MaiTai Global on the intersection of science and high performance. At the Flow Genome Project, he leads a team of the world’s top scientists, athletes and artists dedicated to mapping the genome of the peak-performance state known as Flow. Jamie and Steven have co-penned their new book Stealing Fire: How Silicon Valley, the Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work, out next month. The book explores four years investigating the leading edges of this revolution—from the home of SEAL Team Six to the Googleplex, the Burning Man festival, Richard Branson’s Necker Island, Red Bull’s training center, Nike’s innovation team, and the United Nations’ Headquarters. And what they learned was stunning: In their own ways, with differing languages, techniques, and applications, every one of these groups has been quietly seeking the same thing: the boost in information and inspiration that altered states provide. Listeners will know I’m a big believer in the power of flow and a huge fan of co-author Steven Kotler’s earlier work, The Rise of Superman - and if you haven’t listened to it already, check out episode #15 on how flow can help you increase productivity by 500%. This episode was jam packed with value bombs. Learn how to find your optimal creative state using everything from exercise and meditation to micro-dosing on LSD and hallucinogens!   Topics Covered: - What is flow - The neuroscience of flow, meditative, psychedelic and peak sexual states - What inhibits you from getting into your optimal creative state - Why brainstorming and all-nighters don't really work - Anandamide: the creativity molecule, why you need it to be creative and how to increase your production of it - Why the human mind only consciously processes 0.002% of its surroundings and how to tap into the other 99.998% - Micro-dosing on psychedelics and hallucinogens - How to create the optimal creative environment for your team - Is biohacking worth it? - Spiritual materialism - Getting back into the flow state after being interrupted - Priming practices to optimise your morning and day   Show Notes: 1) Flow Genome Project: flowgenomeproject.com 2) Flow Genome Project Facebook Page: facebook.com/Flowgenome 3) Stealing Fire website: stealingfirebook.com 4) Stealing Fire on Amazon: https://amzn.to/2NSSg3S   ---   I hope you enjoyed this episode. If you’d like to receive a weekly email from me, complete with reflections, books I’ve been reading, words of wisdom and access to blogs, ebooks and more that I’m publishing on a regular basis, just leave your details at www.futuresquared.xyz/subscribe and you’ll receive the very next one. Listen on Apple Podcasts @ goo.gl/sMnEa0 Also available on: Spotify, Google Play, Stitcher and Soundcloud Twitter: www.twitter.com/steveglaveski Instagram: www.instagram.com/@thesteveglaveski Future Squared: www.futuresquared.xyz Steve Glaveski: www.steveglaveski.com Medium: www.medium.com/@steveglaveski

Modern Stories Mix episode 16 takes us on a class trip hosted by your baffled guide, Nisse Greenberg. For more information about Nisse and about this podcast, please visit the show page. In-story music, “Anandamide,” comes from Distant 294. Attributions can be found on the show page.

Welcome back to another episode of The Cannabis Cure Uk Freedom News Podcast recorded on 29th of May with Greg Cure de Hoedt and Johnny Lion! E-petition to Legalise activities with cannabis! http://epetitions.direct.gov.uk/petitions/29 In the News Sheffield Growers Get Reduced Sentence - despite reading this story there has been another developent in the battle of Sheffield! Check it out on Cannabis Cure UK http://cannabiscure.co.uk/evil-sheffield-judges-spend-tax-payer-money-locking-up-patients/ ALERT More contaminated drugs – Dorset Police Issue warning - http://a1.sphotos.ak.fbcdn.net/hphotos-ak-ash2/p480x480/150102_242460432526728_100002883196982_387985_1063606865_n.jpg UPDATE PICTURE OF THE DEADLY DRUG LACED WITH PMA: https://twitter.com/Release_drugs/status/209232191329275904/photo/1 BEWARE: Daily Mail have reported this is Ecstacy - It may be sold as Pink E but it could be very toxic. Please contact Release on Tel: +44 (0)20 7324 2989 if you need any advice or these appear in your area. Plymouth - Cambridgeshire - Liverpool Ian Duncan Smith wants to strip heroin addicts from having incapacity benfit and push them on to job seekers. (http://blogs.independent.co.uk/2012/05/23/taking-away-benefits-from-heroin-users-wont-solve-anything/) An Interview with Erin from INPUD who is a prescription heroin patient that can take home and self inject pure clean pharmaceutical heroin and her life is now back on track but she uses 3 times daily wit self-injecting administration...AT HOME! - REGULATED DOSAGE - CLEAN - STABLE - JOB - FAMILY - Hear how her life has changed now she doesn't have to score. UKCSC - West Midlands Cannabis Community First Meeting - An Interview with Sarah Martin (via Skype!) Thanks to Richard and Alice for putting on a great event and being awesome hosts for us traveling to these meetings! http://www.cannabiscure.co.uk//ukcsc

The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and the immune system resulting in chronic inflammation, pain and trophic changes. This interaction may be mediated by chronic stress which is thought to activate the endogenous cannabinoid (endocannabinoid) system (ECS). We conducted an open, prospective, comparative clinical study to determine plasma level of the endocannabinoid anandamide by high-performance liquid chromatography and a tandem mass spectrometry system in 10 patients with CRPS type I versus 10 age- and sex-matched healthy controls. As compared to healthy controls, CRPS patients showed significantly higher plasma concentrations of anandamide. These results indicate that the peripheral ECS is activated in CRPS. Further studies are warranted to evaluate the role of the ECS in the limitation of inflammation and pain. Copyright (C) 2009 S. Karger AG, Basel

Background: Endogenous ligands of cannabinoid receptors ( endocannabinoids), in particular anandamide ( arachidonylethanolamide), have been recognized as being of crucial importance in a variety of physiological functions. Plasma concentrations of anandamide have been measured in a number of investigations; however, discrepant data on "normal'' anandamide plasma concentrations were reported. Since this might be caused by pre-analytical variables, we investigated the impact of different sample handling conditions on measured plasma anandamide concentrations. Methods: Blood samples were taken from healthy volunteers in EDTA- or heparin-containing tubes; whole blood samples were kept at +4 degrees C, room temperature, or 37 degrees C, respectively, for up to 120 min before obtaining plasma by centrifugation. Plasma anandamide concentrations were measured by an isotope-dilution liquid chromatography tandem mass spectrometry ( LC-MS/MS) method. Results: A marked time- and temperature-dependent increase in plasma anandamide concentrations ex vivo was observed in both EDTA- and heparin-containing tubes. Mean anandamide concentrations approximately doubled when EDTA samples were kept at 4 degrees C for 60 min before centrifugation {[}immediately centrifuged, 1.3 mg/L ( SD 0.3 mg/L); 2.8 mg/L ( SD 0.5 mg/L) after storage for 60 min; n=12). After storage of heparinized whole-blood samples for 120 min at 37 degrees C, a mean plasma anandamide concentration of 11.9 mg/L ( SD 1.8 mg/L) was found. In cell-free plasma, no increase in anandamide concentrations was found. Conclusion: Anandamide is released from blood cells ex vivo at a very high rate; therefore, strictly standardized pre-analytical protocols have to be applied for plasma anandamide determination.