Podcasts about therapeutic strategies

In this solo episode of The Red Light Report, Dr. Mike explores the profound connection between mitochondrial health and oral disease. He reviews three recent studies highlighting how red light therapy, methylene blue, and compounds like urolithin A can support oral tissues, reduce inflammation, and even impact systemic conditions like diabetes and neurodegeneration. From root canal innovations to mitophagy in periodontitis, this episode is full of cutting-edge insights and practical applications for anyone interested in longevity, biohacking, or oral health optimization.Key Topics Covered:Study #1: Methylene Blue + Graphene Oxide for Root Canal Photodynamic Therapy• Combining methylene blue and reduced graphene oxide with red light therapy significantly improves antibacterial and antifungal effects in root canals.• Highlights the synergy between methylene blue and red light.• Dr. Mike shares how his nighttime routine—using BioBlue Calm and a red-light toothbrush—may create a low-level photodynamic therapy effect in the mouth.Study #2: Mitophagy in Periodontal Disease• Mitophagy (mitochondrial autophagy) plays a key role in managing inflammation, bone remodeling, and cell death in gum disease.• Key interventions to enhance oral mitophagy:• Urolithin A (strong Pink1/Parkin pathway activator)• Resveratrol, Melatonin (support mitochondrial quality)• Berberine, Curcumin, Metformin (via AMPK activation)• NR, Quercetin (via SIRT1 + PGC-1α pathway)Study #3: Mitochondrial Dysfunction Links Oral and Systemic Diseases• Periodontitis driven by mitochondrial dysfunction is linked to diseases like diabetes, cardiovascular disease, and neurodegeneration.• Key issues:• Impaired mitochondrial fusion/fission, biogenesis, and mitophagy.• Excessive ROS and mitochondrial DNA leakage fuel inflammation.• Poor mitochondrial function impairs periodontal stem cell regeneration.• Therapeutic approaches:• Antioxidants (CoQ10, resveratrol, melatonin, curcumin, EGCG)• Photodynamic therapy (methylene blue + red light)• Mitochondria-targeted compounds to modulate apoptosis and inflammation.Dr. Mike's Takeaways• Oral mitochondrial health is foundational—not isolated from systemic health.• Red light therapy and methylene blue offer powerful synergistic effects, even in oral applications.• A mitochondria-first approach may provide long-term protection against oral and systemic disease.   If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: 00:00 – Introduction: Mitochondrial Health & Podcast Focus 00:32 – Announcements: Health Alchemy Bundle & Upcoming Events 06:18 – Study 1: Methylene Blue & Red Light Therapy for Root Canal Treatment 08:42 – Methylene Blue Benefits Recap 13:37 – Study 1 Discussion: Photodynamic Therapy Enhancements 16:57 – Practical Application: Methylene Blue for Oral Health 19:40 – Study 2: Mitophagy in Periodontal Disease 23:46 – Targeted Mechanisms to Enhance Mitophagy 28:42 – Study 3: Mitochondrial Dysfunction in Periodontitis & Systemic Diseases 31:38 – Therapeutic Strategies for Mitochondrial Health 41:44 – Integrative Mitochondrial Therapies 47:02 – Conclusion: Mitochondrial Dysfunction as a Core Issue 50:45 – Closing Thoughts & Upcoming Events - Articles referenced in episode:Synthesis, characterization, and application of methylene blue functionalized reduced graphene oxide for photodynamic therapy in root canal treatmentMitophagy and Its Significance in Periodontal DiseaseMitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies - Get over $6,000 worth of wellness education from top experts for $50! The Health Alchemy BundleThis is an amazing opportunity put together by Carrie Bennett and Sarah Kleiner! This Bundle is collection of 60+ eBooks, courses, and other resources available for $50 at a mind-blowing 99% discount.     This massive collection of resources is rooted in the science + spirituality of healing with nature, which cover topics like: Circadian & quantum biology Mental, emotional, & spiritual health Nutrition, minerals, & supplementation (when necessary) Herbalism & homeopathy Movement, posture, & fitness Hormonal health, pregnancy, & parenting And even specific issue support—from healing autoimmunity to improving sleep, & more This is a limited opportunity that goes through TOMORROW, May 23rd, so act now and don't miss out!   Get The Health Alchemy Bundle by clicking here! - Upcoming BioLight Events:   Biohacking Conference - May 28 - 30 (Austin, TX)   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Introducing the Newest BioBlue Supplement! The most comprehensive, powerful mitochondrial support supplement on the market ...   What is The Fountain of Youth in simple terms? An unparalleled supplement for brain power, energy, and longevity This supplement is like a high-performance tune-up for your brain and body. It combines powerful natural and science-backed ingredients to help you think clearer, feel more energized, and support your long-term health.The BioBundle automatically saves you 15% on both of the supplements you choose.   For the next two weeks, SAVE 20% on your order of BioBlue Fountain of Youth! Simply use code FOY20 Code expires 5/29, midnight PST   Click here to check out BioBlue Fountain of Youth - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

On this episode, we discuss multiple sclerosis and describe its clinical presentations, types, and pathophysiology. We compare and contrast the efficacy, safety profiles, and clinical use of disease-modifying agents, supportive therapies, and monitoring strategies in the treatment of multiple sclerosis.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website: https://www.freece.com/ If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast. Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. If you purchase an annual membership, you'll also get a free digital copy of High-Powered Medicine 3rd edition by Dr. Alex Poppen, PharmD. HPM is a book/website database of summaries for over 150 landmark clinical trials.You can visit our Patreon page at the website below:  www.patreon.com/corconsultrx We want to give a big thanks to Dr. Alex Poppen, PharmD and High-Powered Medicine for sponsoring the podcast..  You can get a copy of HPM at the links below:  Purchase a subscription or PDF copy - https://highpoweredmedicine.com/ Purchase the paperback and hardcover - Barnes and Noble website We want to say thank you to our sponsor, Pyrls. Try out their drug information app today. Visit the website below for a free trial: www.pyrls.com/corconsultrx We also want to thank our sponsor Freed AI. Freed is an AI scribe that listens, prepares your SOAP notes, and writes patient instructions. Charting is done before your patient walks out of the room. You can try 10 notes for free and after that it only costs $99/month. Visit the website below for more information: https://www.getfreed.ai/  If you have any questions for Cole or me, reach out to us via e-mail: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com

Send us a textIn this mailbox episode, we dive into a listener question from Amy (name changed for privacy), who is struggling with the trauma bond with her narcissistic and emotionally neglectful mother. Amy shares her experience of emotional neglect, manipulation, gaslighting, and rejection—all while navigating the complicated reality of trying to maintain boundaries.Drs. Gemma and Justine discuss: ✔ What a trauma bond with a parent looks like – Why it's so difficult to break free ✔ The cycle of hope & rejection – Why emotionally neglectful parents keep you in a state of longing ✔ How narcissistic parents offload their shame onto their children – Understanding the “shame exchange” ✔ Why boundaries feel impossible with a narcissistic mother – The emotional toll of walking on eggshells ✔ Grief and healing – The painful but necessary process of accepting that your mother will never be the mother you needed ✔ Moving forward – Why reparenting yourself is key, and how to start choosing healthier relationshipsThis is a deeply validating episode for anyone struggling with a difficult or narcissistic parent. If you've ever felt stuck in an unhealthy dynamic, confused by your mother's inconsistent behavior, or burdened with guilt for setting boundaries, this discussion is for you.

Send us a textIn this episode, Dr Gemma takes a deep dive into one of the most common and persistent life patterns—people-pleasing. If you've ever found yourself constantly prioritizing others' needs over your own, struggling to say no, or feeling exhausted from always trying to keep the peace, this episode is for you.She explores:✅ What people-pleasing really is and why it's not just one behavior but a collection of patterns ✅ The three main schemas that drive people-pleasing ✅ How early experiences and conditioning shape this pattern and why it can be hard to break ✅ Six powerful self-reflection questions to help you tune into yourself, your needs and your emotionsThese six foundational questions are designed to help you:

Podcast Episode Summary: The Truth About Jodi Hildebrandt's Addiction Treatment Methods In this episode, we're diving deep into the controversial practices of Jodi Hildebrandt, whose addiction treatment strategies have come under scrutiny following a lawsuit and allegations of abuse. As an addiction counselor, I'll break down her methods, compare them to science-backed recovery approaches, and explore what truly works in addiction treatment.

Send us a textEpisode Description:Are you dating someone new and wondering if they're truly a good match? Or do you have a pattern of attracting emotionally unavailable or narcissistic partners? In this episode, Gemma breaks down The 7 Deadly Sins of the Narcissistic Dater—key warning signs that indicate deeper personality issues and potential toxic relationship dynamics.These signs often reveal themselves early—sometimes even on the first date. Recognizing them before you get emotionally invested can save you from heartbreak and manipulation.These behaviors aren't just annoying quirks—they're significant predictors of toxic relationship patterns. I also share 2 real success stories from women who've identified these red flags early, broken their old patterns, and found secure, emotionally available partners.Resources Mentioned in This Episode:

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Get your 2025 decluttering inspiration calendar: http://www.overcomecompulsivehoarding.co.uk/2025  Come to a Dehoarding Accountability Zoom Session: http://www.overcomecompulsivehoarding.co.uk/ticket Subscribe to the podcast: https://www.overcomecompulsivehoarding.co.uk/subscribe Podcast show notes, links and transcript: http://www.overcomecompulsivehoarding.co.uk/  In today's episode, I ask Dr Chia-Ying Chou about the complex interplay between grief and hoarding. We'll explore how emotions like grief can trigger hoarding behaviour, the role an inner critic plays, and learn all about compassion-focused therapy – including why it's so much easier to offer compassion than to receive it. The timing is perfect, coinciding with National Grief Awareness Week in the UK. Grief and Hoarding Discussion Chia-Ying Chou discusses the non-direct link between grief and hoarding based on clinical experience. Factors such as resistance to grieving and avoiding vulnerability exacerbate hoarding. Grief can trigger hoarding behaviour to maintain a sense of control and avoid confronting loss. Host shares personal experiences of how grief intensified their hoarding behaviour. Grief and Possessions People keep deceased loved ones' belongings as a way to preserve their existence. Chou mentions the ambiguous preservation of loved ones through items. Anxiety and resistance to facing grief make organising or discarding possessions difficult. Complex Emotions in Grief Host reflects on the unexpected emotions in grief, like anger or impatience. Therapeutic Strategies for Grief and Hoarding Chou compares addressing resistance to grief to preparing for a challenging hike. Emphasis on resourcing, preparing mentally, and gathering support. Suggestions for a "baby-step" approach to facing fears and emotions. Inner Critic and Grief Host discusses journey with their inner critic and finding new approaches to handle it. Chou highlights how internal criticism is often related to grief and missed opportunities. Compassion-Focused Therapy (CFT) Integration of Western psychotherapy and Buddhist philosophy for addressing psychological challenges. Difficulty in receiving or directing compassion towards oneself. Connections Between Hoarding, Trauma, and Grief Patterns of loss, either tangible or intangible, among those who hoard. Episode ties with National Grief Awareness Week in the UK. Cultivating Compassionate Companions Idea of cultivating an imaginary compassionate companion for emotional support. Emphasis on emotions being a part of persona, not the true self. Emotions and Grief Management Pacing yourself. Chou recommends creating space for emotions to surface naturally. Encouragement to welcome emotions as a creative process in internal space. Examine fears and take small steps to engage with feelings.

In this insightful episode, we explore the transformative role of play and playfulness in paediatric occupational therapy from multiple perspectives. From real-life case studies to theoretical discussions on the STEPPSI model and polyvagal theory, we uncover how play enhances child development and therapy. Learn about the challenges and triumphs therapists face in incorporating fun into clinical practice, and discover strategies for balancing playful engagement with therapeutic goals. Through stories, research, and practical tips, we highlight the profound impact of playful interactions and social dynamics in fostering growth and emotional regulation in children.00:00 Exploring Play in Child Development01:16 The Origins and Evolution of STEP SI05:24 Personal Journeys into Pediatric Occupational Therapy08:05 The Vulnerability and Joy of Play10:03 Balancing Playfulness and Professionalism20:55 Clinical Reasoning in Play-Based Therapy25:18 Playfulness vs. Play: Definitions and Applications28:45 Case Study: Attuned Play in Therapy33:19 Struggles with Play and Skill Development34:28 Letting Go of the Agenda35:30 A Breakthrough in Play38:22 The Importance of Play in Therapy39:28 Navigating Play and Regulation41:31 Personal Reflections on Play45:20 Autonomic Nervous System in Play47:15 Grandchildren and Play Dynamics53:06 Therapeutic Strategies in Play59:14 Concluding Thoughts on PlayConnect with us: Instagram: https://www.instagram.com/spiritedconversations_ot/Facebook: https://www.facebook.com/spiritedconversationsOTYouTube: https://www.youtube.com/@spiritedconversations_OTWebsite: https://www.spiritedconversationspodcast.com/ Loved this episode and want an easy cost-free way to support us? Subscribe to our youtube channel! Hosted on Acast. See acast.com/privacy for more information.

In this informative episode, Nurse Doza explores the complexities of Hashimoto's thyroiditis, an autoimmune disorder affecting the thyroid. He delves into the root causes beyond just thyroid dysfunction, discusses manageable lifestyle changes, highlights the liver's crucial role, and emphasizes the importance of targeted supplementation. This comprehensive overview provides practical insights for those living with Hashimoto's, offering hope and actionable steps towards better health. 5 KEY TAKEAWAYS Hashimoto's often stems from previous infections, traumatic events, or lifestyle factors, not just thyroid issues. A gluten-free diet can significantly reduce thyroid antibodies associated with Hashimoto's. Managing stress is crucial, as it can trigger Hashimoto's flare-ups. The liver plays a vital role in thyroid hormone conversion and function. Targeted supplementation, especially zinc, selenium, and liver support, can improve Hashimoto's management. FEATURED PRODUCT Double the power with our Liver Boost and Berberine plus combo. This powerful duo is designed to support optimal liver function and metabolic health—key factors in managing Hashimoto's thyroiditis as discussed in this episode. By enhancing liver health, you can potentially improve thyroid hormone conversion and reduce inflammation, addressing the root causes of Hashimoto's beyond just thyroid function. SHOP HERE   TIMESTAMPS 00:00 START 01:00 Introduction to Hashimoto's thyroiditis 02:00 Previous infections and their role in Hashimoto's 05:00 Traumatic events and thyroid health 08:00 Importance of proper thyroid testing 11:00 Gluten's impact on thyroid health 14:00 Managing Hashimoto's through lifestyle changes 17:00 The liver's role in thyroid function 20:00 Nutrient deficiencies affecting thyroid health 22:00 Benefits of dry sauna for Hashimoto's 24:00 Importance of supplements in managing Hashimoto's   RESOURCES "Viruses and thyroiditis: an update" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654877/ "Posttraumatic stress disorder and risk of selected autoimmune diseases among US military personnel" https://pubmed.ncbi.nlm.nih.gov/30488818/ "Nutritional Approach to Thyroid Health: An Overview of the Current Evidence" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101513/ "Hashimoto Thyroiditis: An Update on Pathogenic Mechanisms, Diagnostic Protocols, Therapeutic Strategies, and Potential Malignant Transformation" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478900/ "Thyroid Hormones and the Liver: A Regulatory Network" https://link.springer.com/article/10.1007/s40618-020-01208-6 "The interrelationship between thyroid gland and liver: a review" https://www.sciencedirect.com/science/article/abs/pii/S0300508921006064 "Far-infrared therapy for cardiovascular, autoimmune, and other chronic health problems: A systematic review" https://onlinelibrary.wiley.com/doi/10.1155/2018/1857413  

Webinar Highlights Podcast: Join Professor Christopher Ritchlin, and Professor Philip Mease as they discuss the recent webinar hosted on the IMID Forum ‘Evolving Therapeutic Strategies for Psoriatic Diseases: Not all IL-23s are Created Similar - Part 2'. Watch them discuss key highlights from the webinar including the burden of PsA and PsO, the similarities and differences in pathology in skin and joints across psoriatic arthritis, and a special focus on IL-23, and its clinical data and impact across different tissue domains.

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]

CME credits: 1.00 Valid until: 15-07-2025 Claim your CME credit at https://reachmd.com/programs/cme/navigating-traditional-treatment-options-current-therapeutic-strategies-and-their-limitations-for-residual-symptoms-in-mdd/26464/ This series of bite-sized episodes contains important information on identifying and treating residual symptoms in major depressive disorder (MDD). Drs. Joseph Goldberg and Manpreet Kaur Singh discuss best practices for recognizing early symptoms, reaching a diagnosis, and treating residual symptoms in patients with MDD.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/GJT865. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Bladder Cancer Advocacy Network. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported through educational grants from Astellas and Pfizer, Inc., Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC (which are both Johnson & Johnson companies), and Merck & Co., Inc.Disclosure information is available at the beginning of the video presentation.

Parkinson's disease is a neurodegenerative disorder characterized by uncontrollable movements, stiffness, and cognitive decline. Curious? Come learn more! Please rate, review, and subscribe and if you have any questions, comments, concerns, queries, or complaints, please email me at neuroscienceamateurhour@gmail.com or DM me at NeuroscienceAmateurHour on Instagram.Also if you have the means/desire to financially support this podcast - please go to https://www.buymeacoffee.com/neuroscienceI really appreciate it!!!Citations and relevant papers are below. National Institute on Aging. Parkinson's Disease: Causes, Symptoms, and Treatments. National Institute on Aging. Hogg E, Frank S, Oft J, Benway B, Rashid MH, Lahiri S. Urinary Tract Infection in Parkinson's Disease. Journal of Parkinson's Disease. 2022;12(3):743-757. ‌Yu J. Stages of Parkinson's | Parkinson's Foundation. www.parkinson.org. Published 2022. ‌Zhang ZX, Dong ZH, Román GC. Early Descriptions of Parkinson Disease in Ancient China. Archives of Neurology. 2006;63(5):782. ‌2-Minute Neuroscience: Direct Pathway of the Basal Ganglia. www.youtube.com. 2-Minute Neuroscience: Indirect Pathway of the Basal Ganglia. www.youtube.com. ‌Thanvi B, Lo N, Robinson T. Levodopa-induced dyskinesia in Parkinson's disease: clinical features, pathogenesis, prevention and treatment. Postgraduate Medical Journal. 2007;83(980):384-388. Zhang JF, Wang XX, Feng Y, Fekete R, Jankovic J, Wu YC. Impulse Control Disorders in Parkinson's Disease: Epidemiology, Pathogenesis and Therapeutic Strategies. Frontiers in Psychiatry. 2021;12. Hisahara S, Shimohama S. Dopamine Receptors and Parkinson's Disease. International Journal of Medicinal Chemistry. 2011;2011:1-16. Houston. Tmc.edu. Published October 20, 2020. https://nba.uth.tmc.edu/neuroscience/m/s3/chapter04.html‌Ovallath S, Sulthana B. Levodopa: History and Therapeutic Applications. Annals of Indian Academy of Neurology. 2017;20(3):185-189. ‌Levodopa | Parkinson's Foundation. www.parkinson.org. https://www.parkinson.org/living-with-parkinsons/treatment/prescription-medications/levodopa‌Kelly MJ, Baig F, Hu MTM, Okai D. Spectrum of impulse control behaviours in Parkinson's disease: pathophysiology and management. Journal of Neurology, Neurosurgery & Psychiatry. 2020;91(7):703-711. ‌Gerfen CR, Surmeier DJ. Modulation of Striatal Projection Systems by Dopamine. Annual Review of Neuroscience. 2011;34(1):441-466. ‌Sayare S. The Woman Who Could Smell Parkinson's. The New York Times. https://www.nytimes.com/2024/06/14/magazine/parkinsons-smell-disease-detection.html. Published June 14, 2024. ‌Blandini F, Nappi G, Tassorelli C, Martignoni E. Functional changes of the basal ganglia circuitry in Parkinson's disease. Progress in Neurobiology. 2000;62(1):63-88. ‌Lanciego JL, Luquin N, Obeso JA. Functional Neuroanatomy of the Basal Ganglia. Cold Spring Harbor Perspectives in Medicine. 2012;2(12):a009621-a009621. Climate ConfidentWith a new episode every Wed morning, the Climate Confident podcast is weekly podcast...Listen on: Apple Podcasts SpotifySupport the Show.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/QSV865. CME credit will be available until May 23, 2025.On Target: Understanding the Impact of PSMA for Diagnostic and Therapeutic Strategies in Prostate Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Blue Earth Diagnostics, Lantheus Medical Imaging, and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

Please visit answersincme.com/CGH860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in pulmonology discusses evidence and guidance on using multimodal approaches for managing patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Upon completion of this activity, participants should be better able to: Identify the continued needs with the currently available therapies for inoperable CTEPH; Review the clinical evidence for multimodal approaches in inoperable CTEPH in the context of currently available therapies; and Outline clinical factors that may facilitate optimal therapeutic selection for patients with inoperable CTEPH.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CJD865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until April 24, 2025.Treatment Advances and Individualized Therapeutic Strategies in Prostate Cancer: Expert Insights on Key Evidence, Practical Tips for Personalized Therapy, and Clinical Integration Approaches In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and ZERO Prostate Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by medical education grants from Astellas and Pfizer, Inc., Exelixis, Inc., Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC., and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.

Webinar Highlights Podcast: Join Professor Iain McInnes and Associate Professor Laura Coates on the Immune-Mediated Inflammatory Disease Forum in their discussion on the recent webinar “Evolving Therapeutic Strategies for Psoriatic Diseases: Not all IL-23s are Created Similar”. Watch them discuss key highlights from the webinar including the burden of PsA and PsO, the pathophysiology of IL-23 inhibitors compared with TNF and IL-17 inhibitor therapies, and the relationship between IL-23 inhibitor MOA variation and real-world patient data.

Join us on a transformative journey in this episode of "Mr. and Mrs. Therapy," where we have the privilege of hosting Erica Holmes, a distinguished Licensed Marriage and Family Therapist (LMFT) with a passion for supporting working mothers. Erica brings her expertise to the forefront, addressing the dual challenges of managing high-stress careers while embracing the pivotal role of motherhood. In today's fast-paced world, mothers are often caught in the whirlwind of professional ambition and familial responsibilities. Erica, through her therapeutic lens, offers unique insights into creating a harmonious balance that nurtures both career aspirations and the well-being of the family. What You'll Discover in This Episode: The Psychological Impact of Career Stress on Mothers: Erica elucidates the complex emotions and stressors faced by mothers in demanding careers, exploring the psychological implications and offering coping mechanisms. Therapeutic Strategies for Balance: Learn about tailored therapeutic approaches that assist mothers in navigating the challenges of work-life balance, drawing from Erica's rich experience as an LMFT. Creating a Supportive Environment at Home and Work: Discussion on how to cultivate understanding and support within professional environments and at home to foster a balanced life. Real-life Success Stories: Be inspired by stories from mothers who have successfully navigated the path to balance, highlighting practical examples and actionable advice. Self-Care and Mental Wellness: A deep dive into the importance of self-care for mental health, with Erica providing guidance on how mothers can prioritize their well-being amidst the chaos. Empowerment for Working Mothers: Erica shares empowering messages and affirmations to uplift mothers feeling the weight of their dual roles, reinforcing the idea that they are capable of achieving both personal and professional fulfillment. Connect with Tim & Ruth:  15 Minute Free Consultation Start healing now! Set up a Coaching Session [Remember, our podcast is here to spark conversations and offer insights. Join our community on our Mr. and Mrs. Therapy Podcast Group, share your experiences at podcast@mrandmrstherapy.com, and if you're seeking more personalized advice, consider booking your free coaching consultation. Please note, this podcast is for informational purposes only and is not intended to provide diagnosis or treatment.]

Featuring perspectives from Dr Melissa Johnson, including the following topics: Role of biomarker testing in optimal selection of first-line therapy for patients with non-small cell lung cancer (NSCLC) (0:00) Efficacy and safety with datopotamab deruxtecan for previously treated NSCLC (15:45) Antitumor activity with and current status of CEACAM5-targeted therapy for relapsed NSCLC (30:24) Evolution of drug development and clinical research (37:56) Key findings with sacituzumab govitecan for NSCLC (41:59) Telisotuzumab vedotin for patients with NSCLC and MET expression (48:44) Recent findings with tumor treating fields for metastatic NSCLC after disease progression on platinum-based therapy (50:49) Other novel antibody-drug conjugates under investigation for NSCLC (55:26) Case: A woman in her mid 50s with recurrent extensive-stage small cell lung cancer who developed pneumonitis on ifinatamab deruxtecan (59:05) Case: A woman in her early 60s with complete response to dose-reduced patritumab deruxtecan (1:00:15) CME information and select publications  

Dr Melissa Johnson from Sarah Cannon Research Institute in Nashville, Tennessee, discusses available data with antibody-drug conjugates with established and investigational targets in patients with non-small cell lung cancer.

Dr Melissa Johnson from Sarah Cannon Research Institute in Nashville, Tennessee, discusses available data with antibody-drug conjugates with established and investigational targets in patients with non-small cell lung cancer, moderated by Dr Neil Love. Produced by Research To Practice. CME information and select publications here (https://www.researchtopractice.com/OncologyTodayCEACAM5NSCLC23).

We're re-running an important episode on Alzheimer's disease — a topic that touches many people. We still don't have a complete understanding of the disease and that makes it hard to design effective therapies. In 2022, Russ Altman sat down with mechanical engineer Ellen Kuhl who offered a glimpse into the way she's using computational modeling to help improve our understanding of Alzheimer's disease.Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) Introduction Russ introduces the episode on Alzheimer's disease, highlighting its global impact, challenges treating it, and Dr. Ellen Kuhl's research on it.(00:02:08) The Approach and Research MethodsEllen Kuhl discusses her lab's interdisciplinary approach, and method of using existing data to create dynamic models to study the brain's lifecycle and degeneration in Alzheimer's disease.(00:03:46) Key Features of Alzheimer's Disease and DetectionBiomarkers of Alzheimer's, their role in brain cell death and cognitive decline, and the possibilities for early detection methods of these protein issues.(00:07:20) How Computational Models FunctionHow the models integrate various data points and physics principles to comprehensively understand Alzheimer's progression.(00:08:43) Spread of the DiseaseExploring the mechanisms of how Alzheimer's spreads from cell to cell in the brain, and the progression through the lobes of the brain, regardless of the cause genetic or trauma induced.(00:12:33) Interdisciplinary Collaboration The challenges and benefits of working as a mechanical engineer in Alzheimer's research and the opportunities of a multidisciplinary approach.(00:14:33) Alzheimer's Drug Development Modeling a controversial Alzheimer's drug, its potential impact, and the importance of early diagnosis for effective treatment.(00:16:04) Transition to COVID Research and ModelingHow the Alzheimer's model was rapidly adapated to study the spread of COVID-19, drawing parallels between brain regions and city networks.(00:18:38) Covid Modeling Learnings and ApplicationsHow their COVID models highlighted the importance of asymptomatic transmission and helped governments with reopening strategies.(00:20:24) Responsible Model Application The rampant and at times irresponsible use of  models during the pandemic, and metrics for measuring credibility of models(00:23:59) COVID Data SharingThe positive legacy of COVID-19, focusing on the accelerated progress facilitated by open and transparent data sharing.(00:24:53) Model Interpretability and ClosingInsights into the importance of model interpretability and the value of reducing complexity to enhance understanding. Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: November 23, 2017 This week on BrainWaves, we build on concepts introduced in episode 65 regarding the non-pharmacologic management of drug-resistant epilepsy. In the next two episodes, you'll hear from Dr. Danielle Becker (Penn) and Dr. Myriam Abdennadher (NIH) on the minimally invasive procedures that can drastically impact the lives of patients with refractory seizures. Produced by James E Siegler. Music by Steve Combs, Jason Shaw, and Josh Woodward. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. REFERENCES Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010;51(6):1069-77. Erratum in: Epilepsia 2010;51(9):1922. PMID 19889013Nilsson L, Farahmand BY, Persson PG, Thiblin I, Tomson T. Risk factors for sudden unexpected death in epilepsy: a case-control study. Lancet 1999;353(9156):888-93. PMID 10093982Tomson T, Nashef L, Ryvlin P. Sudden unexpected death in epilepsy: current knowledge and future directions. Lancet Neurol 2008;7(11):1021-31. PMID 18805738Willie JT, Laxpati NG, Drane DL, et al. Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy. Neurosurgery 2014;74(6):569-84; discussion 584-5. PMID 24618797  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

In this episode, we are again joined by Thomas Seyfried, a Professor in Boston College's Biology Department. Not only does Thomas have immense responsibilities educating students, but he also runs a research program that develops new drug therapies for managing cancer.  Thomas is focused on understanding how metabolic therapy impacts chronic diseases like epilepsy, neurodegenerative lipid storage diseases, and cancer. By looking into alternative cancer treatments, scientists like Thomas are revolutionizing the future of healthcare – using natural metabolic therapies such as caloric restriction, fasting, and ketogenic diets in place of toxic alternatives… Jump in now to uncover: The types of cancer that Thomas is trying to understand and target.  Strategies for cancer management without toxicity.  What fermentation pathways are, and how they can generate energy without oxygen.  The #1 problem that all cancer cells share.  What the origin of cancer is. To learn more about Professor Thomas Seyfried and his work, click here now! Take advantage of a 5% discount on Ekster accessories by using the code FINDINGGENIUS. Enhance your style and functionality with premium accessories. Visit bit.ly/3uiVX9R to explore latest collection. Episode also available on Apple Podcasts: http://apple.co/30PvU9C