Podcasts about cell danger response

In this episode, Dr. Tony breaks down the Cell Danger Response, the research behind why a child's cells shut down energy production, and why that shutdown is actually the nervous system doing exactly what it's designed to do when it senses ongoing threat. He explains why supplements, red light therapy, and NAD+ can feed the cell the raw materials for energy, but none of it holds if the nervous system is still stuck broadcasting danger.You'll learn about the three stages of subluxation, why an upper cervical brainstem subluxation can send a global distress signal to every cell in the body, and why movement, the neurosensory motor system, and the exhausted cerebellum are quietly draining more energy than anything else. This is the missing piece in the mitochondria, microbiome, and methylation conversation: movement.-----Links & Resources:Register for the free Breaking the Cycle of School Struggles Webinar HERE-----Key Topics & Timestamps: 00:00 Why the mitochondrial energy conversation is missing something 02:00 What Dr. Tony sees in every Perfect Storm case history 07:00 Why exhausted kids collapse instead of moving through the world 11:00 What the research says about the brain, mitochondria, and autism 13:00 The real question: not how to make more energy, but where it's going 20:00 What is the Cell Danger Response? 22:00 The three stages of subluxation and nervous system dysregulation 24:00 Why supplements and red light therapy don't hold without this fix 29:00 The missing "M word": movement, proprioception, and the cerebellum 36:00 How INSiGHT Scans and neurospinal EMG find the root cause-- Follow us on Socials: Instagram: @pxdocsFacebook: Dr. Tony Ebel & The PX Docs NetworkYoutube: The PX DocsFor more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care.Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click Here

Dr. John Kim joins the show to discuss mold illness, cell danger response, mitochondrial dysfunction, chronic inflammation, and why many patients remain stuck despite following conventional detox protocols. Together, we explore how environmental toxins, infections, trauma, gut health, and cellular resilience all influence the body's ability to heal and what clinicians can do to better support lasting recovery.We dive into:Cell danger response and its role in chronic illnessHow mold toxins disrupt mitochondria, cell membranes, and energy productionWhy emotional trauma and chronic stress can drive immune dysfunctionThe connection between mold illness, gut health, and the microbiomeWhy some patients react poorly to glutathione, binders, and traditional detox protocolsAdvanced testing for mold illness, inflammation, and mitochondrial healthThe importance of supporting drainage pathways before detoxificationHow mycotoxins contribute to brain fog, fatigue, and neuroinflammationPractical strategies for addressing chronic mold exposure and supporting cellular healingWhy a personalized, root-cause approach leads to better long-term outcomes

Du möchtest mehr am Leben teilhaben, doch Dein Körper zieht immer wieder die Notbremse? Silke Linsenmaier spricht mit Doc Jay, Ärztin und Expertin für Mind-Body Medizin, über Fatigue, Brain Fog und einen Gedanken, der vielen Frauen nach Krebs neue Hoffnung schenken kann: Vielleicht fehlt Deinem Körper keine Kraft. Vielleicht fehlt ihm Sicherheit. Du erfährst, warum Dein Körper nicht gegen Dich arbeitet, sondern versucht, Dich zu schützen, weshalb das Nervensystem eine Schlüsselrolle für Regeneration spielt und wie kleine Sicherheitssignale, Freude und Vertrauen den Weg zurück zu neuer Energie unterstützen können. Eine Folge, die Deinen Blick auf Heilung nach Krebs verändern kann.

In this episode with Dr. Jockers and guest Dr. Tony Jimenez, you will learn how cancer is understood as a complex process shaped by the body's internal terrain rather than a single isolated cause. You'll hear how inflammation, toxicity, and metabolic imbalance can influence disease development and progression in ways most people are never told. You will also discover how integrative oncology approaches can be used alongside conventional care to support the body's healing response.   You will gain a clearer understanding of why genetics account for only a small percentage of cancer cases, while epigenetic and lifestyle factors play a far greater role in how disease expresses itself. The discussion explores how chronic stress, poor sleep, environmental toxins, and unresolved emotional trauma can all impact cellular function over time. You'll also hear how addressing these root factors can help restore balance and support the body's natural defenses.   Explore the connection between nutrition, blood sugar regulation, and cancer biology, and why metabolic health is central to long-term outcomes. The episode breaks down how lifestyle habits such as movement, sleep quality, and nutrient-dense foods contribute to resilience. And you'll gain insight into how integrative tools like detoxification, immune support, and light-based therapies are being used in advanced care settings.   In This Episode:  00:00 Nutrition Isn't Optional 00:21 Meet Dr. Tony Jimenez 05:36 What Cancer Really Is 09:41 Smart vs Stupid Cancers 11:00 Cancer Is a Process 14:25 Genetics vs Epigenetics 17:36 Therapeutic Order Healing 23:53 Cell Danger Response 25:31 Hope4Cancer Assessments 31:03 Mindset Prayer and Healing 33:11 Emotional Trauma Breakthroughs 37:49 Nutrition and Cancer Growth 41:03 Personalized Nutrition Basics 42:42 Clean Foods Low Toxins 43:26 Sugar, Insulin, Inflammation 45:11 Cancer and Sugar Myths 46:44 Food First Supplements Second 48:13 Carbs, Fruit and Activity 51:25 Structured Water Hydration 52:52 Exercise for Longevity 53:42 Light Sleep Hormones 55:36 Sound Light Cancer Therapy 01:03:47 Detox and Modern Toxins 01:05:33 Clinical Trials Chemo Reality 01:08:22 Integrative Chemo IPT 01:09:48 Hope and Closing Message   Get the benefits of apple cider vinegar without the harsh taste in easy veggie capsules, supercharged with turmeric, ginger, Ceylon cinnamon, and lemon to support digestion, blood sugar, and metabolism. Go to paleovalley.com/jockers and use code JOCKERS to save 15% off your order. Clean, convenient daily gut support—take it with meals for best results. Fuel your body with 78 vitamins, minerals, probiotics, adaptogens, and superfoods in one scoop designed to support energy, gut health, and immunity. Tastes great with natural pineapple flavor and costs just $40 a bag with free shipping and 365-day returns. Get yours at quince.com/drjockers and simplify your daily nutrition.   Support thicker, healthier-looking hair with a clean botanical formula featuring rosemary, castor, argan, peppermint, and lavender oils designed to nourish the scalp naturally. Clinical studies highlight rosemary's powerful hair-support benefits—no harsh chemicals or fillers. Visit everbella.com and use code JOCKERS30 to save 30% off your entire order. Help support joints, skin, hair, and recovery with grass-fed, pasture-raised collagen peptides that mix easily into coffee or smoothies with no taste or clumping. Trusted by over 100,000 customers and NSF-certified for sport, it's a simple daily upgrade for longevity support. Go to bubsnaturals.com and use code DRJOCKERS for 20% off your order.   "The goal isn't just to fight cancer. It's to create a body where cancer struggles to survive."   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources:  Go to paleovalley.com/jockers and use code JOCKERS to save 15% off your order. Get yours at quince.com/drjockers Visit everbella.com and use code JOCKERS30 to save 30% off your entire order. Go to bubsnaturals.com and use code DRJOCKERS for 20% off your order.     Connect with Dr. Tony Jimenez: Website - https://hope4cancer.com/ Book - https://a.co/d/05R2FXtz     Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

Dr. John Kim was 33 years old, a practicing functional pharmacist who thought he was living a healthy life, when he walked into the ER with chest pain and was told he was probably fine. He wasn't. An 85% blockage in his LAD, a stent, three days in cardiac ICU, and a month later — a positive test for Bartonella, sky-high aspergillus antibodies, mycoplasma pneumonia, Epstein-Barr, parasites, and severe mercury toxicity traced back to childhood. Two years to clear the Bartonella. Six months for the mold. And a complete reinvention of how he practices medicine. In this conversation with Freddie, Dr. Kim breaks down what functional medicine is getting dangerously wrong right now — the supplement stacking, the endless detox protocols, the practitioners who skip the nervous system entirely — and lays out what actually has to happen first. Heart coherence before supplements. Nervous system regulation before binders. EMDR before mold remediation. And a lipid panel that actually includes lipoprotein A and APO B instead of just chasing LDL numbers. The second half of this episode goes deep on biotoxins and cellular damage in a way you won't hear in most wellness spaces. Dr. Kim explains the cell danger response — why the mitochondria shifts from making energy to playing defense, and why so many people with MCAS, long COVID, Lyme, and autoimmune conditions are completely stuck in that state — and what it actually takes to get out. He breaks down how toxins like heavy metals, mold, and BPA bind directly to DNA in what's called a DNA adduct, why plasma therapies and standard detox protocols don't reach that level of damage, and what does — butyric acid, TUDCA, and a sequenced approach that rebuilds the cell membrane before asking the body to clear anything. He also covers the IGL epigenetic blood test from Germany, protein misfolding, and why the goal of any good practitioner should eventually be to never see their patient again. Find Dr. John Kim at drjohnkim.com and on Instagram at john.pharmd.   Episode Highlights - [00:00] – Dr. John Kim shares the heart attack that changed his life at just 33 years old. - [07:30] – Why clean cholesterol and normal labs didn't prevent a life-threatening cardiac event. - [08:36] – The heart markers beyond cholesterol that deserve more attention. - [10:36] – Heart coherence, gratitude, and how nervous system regulation supports cardiovascular health. - [15:07] – Understanding the Cell Danger Response and why chronic illness gets stuck. - [20:22] – A practical healing hierarchy for mold illness, MCAS, and chronic inflammatory conditions. - [24:59] – Why circadian rhythm may be the most overlooked free intervention in health. - [37:46] – The problem with treating lab results instead of treating the person. - [44:24] – Should people order their own functional lab testing? The benefits and limitations. - [53:57] – A real-world story showing how heart coherence transformed chronic anxiety in six weeks. - [55:59] – The truth about plasmapheresis, detox culture, and expensive biohacking trends. - [01:01:58] – Why lasting healing requires resilience—not lifelong detox protocols.  Connect with Dr. John Kim: Website: https://drjohnkim.com Instagram: https://www.instagram.com/john.pharmd My Circadian App: https://mycircadianapp.com Upgrade Your Health LightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794 Code: beautifullybroken Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD 30% off with Code: BEAUTIFULLYBROKEN MaxGen Labs: https://maxgenlabs.com/BEAUTIFULLYBROKEN StemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52 Code: beautifullybroken CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/freddie.kimmelYouTube: https://www.youtube.com/@beautifullybrokenworld Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episode Highlights With KatieWhy the traditional biochemical model of the body is incomplete...and why the body is electric firstThe shocking amount of energy your body generates each day (about your own body weight in ATP!)Why 90–95% of chronic diseases have mitochondrial dysfunction at the rootHow your mitochondria act not just as powerhouses but as quantum batteries, antennas, and information hubsThe surprising sources of electrons that create cellular voltage...including sunlight, melanin, movement, structured water, and the earth itselfHow infrared light charges your “quantum battery,” while artificial blue light breaks it downWhy hydration with minerals is essential for building cellular charge (and why plain water can ake things worse)The nutrients mitochondria require to function: phospholipids, healthy fats, CoQ10, copper, B-vitamins, carnitine, creatine, and moreWhat redox really means and why redox balance must come before detoxHow a collapse in redox leads to the Cell Danger Response, chronic symptoms, and stalled healingThe many ways modern life drains voltage: lack of sunlight, EMFs, stress, toxins, blue light, poor sleep, dehydration, and circadian disruptionSimple daily strategies to restore voltage...starting with light, minerals, movement, grounding, and sleepHow tools like red/near-infrared light, PEMF, BioCharger, sauna, cold therapy, Juvent, and vibration plates support mitochondrial energyResources MentionedRed light therapyPEMF matBioChargerSaunasPower Plate vibration plateCold plungeJuventJustine ClassThe Body ElectricDr courtney hunt insta and websiteYour spark is light classMineral podcast seriesWater structure pitcher affiliate linkRebounder on amazon

On this episode of The CIRS Group podcast, hosts Jacie and Barbara interview Dr. Andrew Heyman about Dr. Naviaux's cell danger response (CDR) framework and why it can explain stalled recoveries in chronic mold-related illness and CIRS. Heyman describes how mitochondrial “danger mode” drives three phases: initial inflammation (innate immune activation), rebuilding via aerobic glycolysis, and reintegration requiring “all clear” signals like VIP, which positions CIRS as a subset of CDR. He emphasizes total toxic load (mold/biotoxins plus chemicals, metals, infections, gut-derived endotoxins, physical trauma, and emotional trauma), and discusses the neuroendocrine-immune axis (VIP, MSH, PACAP) and autonomic/vagal tone as key to recovery. He outlines his BeyondMold.com five-phase clinical program: environment/binders and chemical detox support, pathogen work, gut optimization, metabolic/hormone rebuilding with nervous system support, and a final readiness-to-heal/phenotyping phase using targeted safety signals (including VIP forms). TIMESTAMPS 00:00 Intro to Dr. Andrew Heyman 02:38 What Is Cell Danger Response? 06:38 CIRS in the context of Cell Danger Response: changing gene expression 12:18 The role of total toxic load and co-infections 16:52 How the nervous system is affected by Cell Danger Response 22:27 Why having a solid practitioner in your corner is so important 23:56 The limitations of CIRS diagnostic testing 28:47 Beyond Mold framework for healing in five phases 37:18 Are you ready to heal? 46:16 Advice for stalled patients 51:14 How to work with Dr. Heyman and Beyond Mold For more information and support, join us at https://thecirsgroup.com WORK WITH DR. HEYMAN: https://beyondmold.com/ Dr. Heyman Q&A mentioned in the outro: https://www.youtube.com/live/EWoki09eHhk Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet!  https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.

For the final episode of The Women's Health Wellness Edit, we sit down with functional medicine expert Dr. John Kim, PharmD, FAARFM to explore why so many people still struggle with brain fog, fatigue, and chronic symptoms despite being "healthy." We dive into the Cell Danger Response, how trauma and chronic stress can impact cellular resilience, and why healing often requires more than diet, supplements, and biohacks. Dr. Kim also walks us through his ENCORE Method for helping the body move out of defense mode and back into healing. This episode is an in-depth and actionable look at how to take control of your body back. Keep in touch with Dr. Kim: https://www.drjohnkim.com https://www.instagram.com/john.pharmd/?hl=en Attend Dr. Kim's upcoming webinar: https://beyonddetox.drjohnkim.com If this episode spoke to you, subscribe and leave a review on your favorite podcast platform or share it with a friend! podcasts.apple.com/us/podcast/slig…od/id1542525641 Follow us on Instagram: www.instagram.com/slightlyspiritualpod/ Follow Cindy on Instagram: www.instagram.com/revealingsoul/ Follow Ali on Instagram: www.instagram.com/alitmoresco/

Pandemic Policies, Vaccines, and Harms to Children: pediatrician and author Dr. Elizabeth Mumper discusses her book “Kids and COVID: Costly Mistakes That Must Never Happen Again.” Mumper argues parents should question authorities, citing early pandemic decisions such as lockdowns, masking, and a “one size fits all” vaccine strategy despite children's low risk from COVID. She supports the Great Barrington Declaration's focus on protecting high-risk groups and criticizes suppression of repurposed treatments like hydroxychloroquine and ivermectin. The discussion raises concerns about mRNA vaccine safety, biodistribution of lipid nanoparticles, underreporting to VAERS, loss of long-term control groups, myocarditis risk in young males, and claims of severe neurologic effects and “turbo cancers.” Mumper describes developmental, educational, and mental-health harms from masking and school closures, challenges vaccine mandates as violating informed consent, explains the cell danger response concept, and criticizes Paxlovid while favoring integrative approaches.

In dieser Episode spreche ich mit Dr. Jacqueline Metzner / Doc Jay über ihre Corona-Infektion im Jahr 2020 und wie die darauffolgende Post Covid bzw. ME/CFS-Erkrankung ihr Leben veränderte. Sie erzählt von den zahlreichen Einschränkungen, die sie bei Bell 10 in Kauf nehmen musste und welche Herausforderungen 23h Bettruhe mit sich brachten. Und wir sprechen natürlich auch darüber, wie sie bei Recherchen schließlich auf die Arbeiten von Arzt Prof. Dr. Robert Naviaux in Bezug auf die Cell-Danger-Response stieß, durch die sie ein neues Verständnis für die Krankheit entwickeln konnte. Heute ist Dr. Metzner /Doc Jay symptomfrei und arbeitet wieder Vollzeit in ihrer Praxis und im Safety Retreat. Darüber haben wir u.a. im Podcast gesprochen: Cell-Danger-Response von Prof. Dr. Robert Naviaux Podcast Episoden bei Johannes von Fasynation Fatigue: Episode mit Mann Rolf zur Cell Danger Respone: https://www.fasynation.de/der-podcast-zum-chronischen-erschoepfungssyndrom-me-cfs?ppplayer=6267e70c344a6b7db2ab7d210e301232&ppepisode=a3c36a450f84f03726eaedca4ee04a80 Episode mit Dr. Metzner / Doc Jay: https://www.fasynation.de/der-podcast-zum-chronischen-erschoepfungssyndrom-me-cfs?ppplayer=6267e70c344a6b7db2ab7d210e301232&ppepisode=d42a2c96f2575f910d74b5f32a802d51 Podcast Chronically ME: https://open.spotify.com/episode/3pnadJbQSSGWHi296wQxMi?si=03462b21e82a4818 Kontakt: Dr. Jacqueline Metzner / Doc Jay IG: @safetyretreat Website Privatarztpraxis Dr. Metzner / Doc Jay: www.dr-metzner.eu Website Safety Retreat: https://www.safetyretreat.com/ Superheld/-innen Ohne Cape E-Mail: superheldenohnecape@yahoo.com IG: @superheldenohnecape Die Inhalte dieser Podcasts dienen der allgemeinen Information und ersetzen keine individuelle medizinische Beratung, Diagnostik oder Behandlung. This podcast is hosted by ZenCast.fm

What if healing is less about doing more… and more about restoring movement, communication, and safety inside the body? In Part Two of The Terrain First Series, Debbie Potts dives deep into the physiology of FLOW — not just physical movement, but the movement of oxygen, lymph, bile, blood, nutrients, waste, nerve signals, and cellular communication. This episode connects together: • The F.L.O.W. Foundation™ • Nervous system regulation & vagal tone • Lymphatic flow & drainage pathways • Bile flow & detoxification • Oxygen delivery & mitochondrial health • The Cell Danger Response theory • Why stagnant physiology creates stagnant health • Why "drainage before detox" matters • How the body shifts from survival mode into repair mode Debbie explains how symptoms like fatigue, brain fog, inflammation, hormone imbalance, digestive dysfunction, and poor recovery may be signs of impaired communication and survival physiology — not simply a lack of willpower. You'll learn why: • Safety before fat loss matters • Capacity before intensity matters • Energy before effort matters • The body must feel safe enough to heal This episode is a deep-dive "rabbit hole" conversation into the connections between the nervous system, mitochondria, microbiome, immune system, and metabolic health — and how restoring FLOW may help create the conditions for resilience, recovery, and longevity. Topics Discussed: The Cell Danger Response Terrain First Strategy Vagus Nerve & Safety Signaling Lymphatic Congestion Bile Flow & Digestion Oxygen Utilization & Mitochondria Drainage Before Detox Metabolic Flexibility Chronic Stress & Survival Physiology Functional Health Foundations for Midlife Performance & Longevity Learn more about coaching, functional lab testing, and PNOĒ Metabolic Testing: DebbiePotts.net Subscribe to The Coach Debbie Potts Show and share this episode with a friend who needs to hear that healing starts with creating safety, resilience, and flow. #TerrainFirst #FLOWFoundation #FutureYouBlueprint #VagusNerve #Mitochondria #FunctionalMedicine #MetabolicHealth #CellDangerResponse #LymphaticHealth #HealthyAging #Longevity #GutHealth #Hormones #MidlifeHealth #Biohacking #CoachDebbiePotts

Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly Maloof, a physician and one of the most innovative voices in personalized medicine, functional medicine, and human performance. Since 2012, she has advised or consulted for over 50 companies across digital health, consumer health, and biotechnology. She pioneered a course on healthspan at Stanford University and founded Adamo Bioscience, a company dedicated to unlocking the science of love as a pathway to healing and human connection. Dr. Maloof brings a rare combination of clinical depth, biohacking credibility, and entrepreneurial range to one of the most overlooked conversations in longevity. Together, Dave and Dr. Maloof dig into the neurobiology of love and attachment, the hormonal drivers of the sex drive and pair bonding, and how chronic isolation wrecks your metabolism at the cellular level. They explore the cell danger response and how toxic relationships, mold exposure, and trauma can lock your cells into a self-protection mode that blocks healing. They also cover psychedelics as hormetic tools, oxytocin as nature's medicine, the placebo response, peptide therapy for mitochondrial repair and anti-aging, and why regenerative medicine is about to rewrite the rules of human lifespan. If you are serious about biohacking your body from the inside out, this episode is essential. You'll Learn: Why human connection is a biological necessity, not a lifestyle preference, and what isolation does to your mitochondria and metabolism How the three neurobiological drives of sex, romantic love, and attachment are wired into your hormones and what happens when they go wrong What the cell danger response is, why it gets stuck, and which peptides, supplements, and therapies help break the cycle How oxytocin drives wound healing, immune function, and the placebo response Why psychedelics work as hormetic love drugs and how they reproduce the neurobiology of romantic love The top peptides for mitochondrial repair, brain optimization, and telomere biology Why Dave and Dr. Maloof believe we have already reached longevity escape velocity How AI is accelerating precision medicine, protein folding breakthroughs, and the future of anti-aging therapeutics Why fasting, breathwork, neurofeedback, and somatic therapies all converge on the same biological reset mechanism How to build the adaptive capacity and bioenergetic reserves to bounce back from anything Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18 - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Molly Maloof, Adamo Bioscience, Stanford University, personalized medicine, functional medicine, healthspan, longevity, biohacking, human performance, anti-aging, regenerative medicine, longevity escape velocity, cell danger response, mitochondria, mitochondrial health, oxytocin, vasopressin, dopamine, serotonin, neurobiology of love, attachment theory, pair bonding, sex drive, hormone replacement therapy, testosterone, estrogen, menopause, andropause, libido, female sexual dysfunction, relationship biology, social health, isolation, community, co-regulation, trauma healing, psychedelics, MDMA, psilocybin, ibogaine, ayahuasca, hormetic stress, social hormesis, neurofeedback, 40 Years of Zen, breathwork, nervous system regulation, HPA axis, cortisol, mast cell activation, histamine, long COVID, mold exposure, phospholipid therapy, glutathione, vitamin C, BPC-157, TB500, SS31, epothilone, SELANK, SEMAX, BDNF, telomere biology, telomerase, peptides, GLP-1, placebo response, wound healing, metabolism, continuous glucose monitoring, gut health, AI, precision medicine, supplements, brain optimization, neuroplasticity Resources: • Grab Molly's Book The Spark Factor: https://www.amazon.com/Spark-Factor-Supercharging-Optimizing-Feeling/dp/0063207206 • Learn More About Dr. Molly's Work: https://drmolly.co/ • Visit Your Healthspan Journey: https://yourhealthspanjourney.mystrikingly.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:28 – Intro 01:39 – COVID Isolation & Its Effects 03:11 – Science of Love & Hormones 04:24 – Psychedelics & Love Chemistry 09:22 – Cell Danger Response 11:07 – AI, Tech & Human Connection 13:20 – Social Connection as Medicine 20:50 – Placebo, Care & Psychedelics 24:49 – Altered States & Healing Modalities 30:09 – Peptides & Longevity Drugs 35:44 – Mast Cell & Personal Health Challenges 43:46 – Regenerative Medicine & The Future 46:17 – Longevity Escape Velocity 50:05 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This podcast comes from this blog post: Energy Reserves, Hormonal Decline, and the Cell Danger Response https://www.naturecurefamilyhealth.com/hormonal-decline-danger-response/ Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

➡️ Get the full show notes and episode breakdown at Biology of Trauma® Podcast - EP 170: What If Safety Is What Your Body Was Taught to Fear? You learned to assess the mood of a room before you walked into it. To listen to the sounds in the house before you got out of bed. To become whoever was needed — quickly, automatically, without being asked. Your nervous system built that skill before you had language for it. And it has been running ever since. In this episode, Dr. Aimie Apigian explains what growing up in an emotionally unsafe or narcissistic household actually does to the developing nervous system — why hypervigilance, people-pleasing, and the inability to fully rest are biological adaptations rather than personality traits, why genuine safety can feel more threatening than the chaos the body learned to navigate, and what it takes to teach a body that has never fully rested that it is now allowed to. This is the biology behind something many people have spent years trying to understand about themselves. Not what happened to them. What happened inside them — and what it will take to change it. In This Episode You'll Learn: [00:00] Why is it so hard to relax even when nothing is wrong — and what is actually happening in the body? [01:40] What is the biological definition of trauma — and why does the event matter far less than the body's response? [04:00] What does unpredictable parenting do to a child's developing nervous system? [06:04] Why do people-pleasing and overachieving become biological survival strategies — not personality traits? [07:28] What happens in the body during chronic hypervigilance? [08:43] When does relational stress start to register as a life threat — and why does this persist into adulthood? [11:00] How does dissociation develop as a biological coping mechanism — and why can't we selectively numb pain? [12:26] Why we cannot feel joy when we learn to numb pain? [17:00] Why is seeking safety not the same as finding it? [19:15] What is true safety? Why does true safety feel unsafe? [21:04] What is microdosing safety — and how does it reprogram a nervous system that has never fully rested? [23:42] Why is it important to create a cellular level biology of safety? [26:00] Why safety needs to be done in a structured way [31:31] Why not analyzing and feeling what we feel can be so challenging? Resources/Guides: Free Guide: Steps to Identify and Heal Trauma by Dr. Aimie Apigian — A 23-page quiz-based guide to help you recognize the patterns of stored trauma in your life, your relationships, and your physical health. Book: The Biology of Trauma by Dr. Aimie Apigian — Chapter 11 covers the biology of toxic and narcissistic parenting. Chapter 4 explains the Cell Danger Response and how the body encodes early experiences. Program: Foundational Journey® — A six-week online process working directly with the nervous system. Builds the biological foundation of safety that has to come first before anything else can hold. Related Podcast Episodes: Episode 69 — How Attachment Shapes Our Biology and Behavior Episode 126 — Neuroception Explained: How Your Nervous System Decides What's Safe and Why It Matters for Healing Episode 127 — Why Your Body Is Wired for Danger: Understanding Trauma's Impact on Your Nervous System Episode 135 — The Hidden Difference Between Stress and Trauma In How The Body Keeps Score Episode 138 — Why Your Body Holds On When Your Mind Has Healed Episode 146 — How Attachment Affects Us for Life: 6 Childhood Pains and How to Repair Episode 163 — Growing Up With Addiction Left a Trauma Your Body Still Carries Episode 167 — What Your Nervous System Learned Before You Could Speak

In this conversation, I sit down with Dr. Eric Balcavage to unpack what's really happening beneath the surface when your body feels stuck, overwhelmed, and unable to heal. We dive into the concept of the cell danger response and why so many people today are living in a chronic state of stress at a cellular level without even realizing it. We also explore the gap between traditional and functional medicine, and why both approaches matter more than we think when used in the right context. Throughout this episode, we challenge the idea that more is always better when it comes to your health. From overloading on supplements to over-optimizing every part of your routine, we talk about how these well-intentioned habits can actually keep you stuck. I walk through real-life examples and ask the hard questions that help you determine whether your body is in a place to heal or simply trying to survive. If you've ever felt frustrated, burnt out, or like nothing is working despite your efforts, this episode will give you a completely new lens to look through. Topics We Cover in This Episode:  Why doing “all the right things” can still keep you stuck The hidden signs your body may be overwhelmed at a cellular level How stress impacts your body in ways most people miss Why some people get worse before they ever get better The surprising reason your routine might be working against you How to tell if your body can actually receive the help you're giving it The real difference between healing and just managing symptoms A simple way to start identifying what your body actually needs If this episode resonates with you, take it as a sign to pause and reassess what your body has been trying to tell you. You don't need more complexity. You need clarity. Don't forget to make sure you're subscribed so you don't miss future episodes. Resources & Links Connect with Dr. Eric Balcavage

☎️ Book Your COMPLEMENTARY CONSULTATION and CALORIE CALCULATION Call: https://calendly.com/d/2p8-mxx-dgf/free-consultation-call-zoom⁠⁠⁠⁠⁠⁠Mitochondria Guide: https://www.vitalityoet.com/mitochondriaWhy are you still bloated… exhausted… reactive… and not losing fat?You're eating clean.You're trying to lower inflammation.You're working on your hormones.You're doing the “right” things.What if the problem isn't your calories, your carbs, or your supplements?What if your body is still operating like it's under threat?In this episode, we're talking about the hidden survival switch that can quietly block fat loss, amplify symptoms, and keep you stuck — even when you're doing everything right.If you feel like your body won't cooperate… this conversation will shift how you see healing, metabolism, and your symptoms completely.Press play.

In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, and Jodi Duval as they break down one of the most important frameworks in Health Optimization Medicine — the Cell Danger Response (CDR). Originally developed by Dr. Robert Naviaux, the Cell Danger Response explains how cells respond to threat, adapt for survival, and either resolve or become "stuck" — leading to chronic disease. This episode walks through the three stages of the CDR, how mitochondria act as both sensors and signaling hubs, and why many modern conditions — from inflammation to chronic illness — are actually stalled healing processes. Most importantly, the team explains how clinicians and individuals can identify where the body is "stuck" and what to do (and NOT do) to support proper resolution. Join us as we delve into: What the Cell Danger Response (CDR) is and why it matters The 3 stages: defense, repair, and resolution How mitochondria act as sensors — not just energy producers Why inflammation is a protective response, not the problem How chronic disease reflects a "stalled" healing process This episode is for you if: You're dealing with chronic inflammation or unresolved health issues You want to understand the root cause of disease beyond symptoms You're a practitioner looking for a systems-based framework You want to optimize health by working with your biology, not against it You can also find this episode on… YouTube: https://youtu.be/NWEq32hlZrE Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/  Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products

Why Your Body Won't Shift Out of Survival Mode (Even When You're Doing Everything Right) In Part 4 of this deep-dive series, we go beyond protein, training, and hormones… and into the control center of your metabolism:

This podcast comes from two blog posts: This is part 1 and this is part 2. Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

In this episode, Dr. Jockers breaks down the truth about cellular inflammation and chronic disease, explaining how inflammation is a life-saving mechanism that can turn harmful when it persists. You'll learn how stressors like infections, nutrient deficiencies, and emotional turmoil create a cascade of inflammation that can damage your body over time.   Dr. Jockers dives into the science behind the cell danger response, showing how the body reacts to injury or threat, and what happens when it gets stuck in a self-perpetuating cycle. Discover the role of NFKB in amplifying inflammation and how it can be triggered by damage-associated or pathogen-associated molecular patterns.   Learn simple yet powerful strategies to calm inflammation, from proper sleep and movement to reducing toxin exposure and balancing your diet with anti-inflammatory nutrients. Dr. Jockers provides actionable tips on how to regain control and heal from chronic inflammation. In This Episode:  00:13 Show Welcome Overview 00:45 Health Coaching Plug 03:19 Inflammation Basics 03:52 Why Inflammation Saves 05:58 Modern Stress Overload 06:44 DAMPs PAMPs Explained 07:39 NFKB Riot Analogy 09:31 What Drives NFKB 14:49 Oxidative Stress Triggers 16:11 Omega Fats Prostaglandins 17:23 Cell Danger Response 17:44 Turn Off Inflammation 17:53 Lifestyle Sleep Sun Move 19:51 Nature Toxins Nutrients 22:10 Key Supplements List 23:02 Final Summary Outro   Looking for a delicious snack that's good for you? Paleovalley Superfood Bars are packed with organic, whole food ingredients like collagen protein, kale, and blueberries—providing all the nutrients your body needs. With flavors like Lemon Meringue and Red Velvet, you can enjoy a treat that supports gut health, joint function, and even wrinkle-free skin. Visit paleovalley.com/jockers and use the code JOCKERS to save 15% on your order today. Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com -  https://renewyourhair.com/drjm/DRJ.   When it comes to cooking, Chef Foundry offers the perfect solution with their P 600 ceramic cookware, which is free from Teflon, PFAS, and plastic coatings. Made with Swiss-engineered ceramic, this cookware makes it easy to prepare healthy meals without the toxins. Take 20% off with code SAFE20 at chefsfoundry.com/jockers and upgrade your kitchen today.     "Your body uses inflammation to prevent infections from spreading and becoming life-threatening." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Snack smarter and save 15% on Paleovalley Superfood Bars with code JOCKERS paleovalley.com/jockers Reignite hair growth with AnaGain Nu, risk-free with a 180-day guarantee and a buy-one-get-one-free deal!  RenewYourHair.com/drjm/DRJ Upgrade to P 600 ceramic cookware and save 20% with code SAFE20 today! chefsfoundry.com/jockers Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

This week we're bringing Jason Earle, founder and CEO of GotMold?, back on our podcast to uncover the hidden health impacts of mold exposure. After discovering that mold in his childhood home was the root cause of his severe allergies and asthma, Jason left a successful Wall Street career to help families identify and solve indoor air quality problems. He explains why using bleach on mold can actually make the problem worse and why the key is removing mold, not just trying to kill it. The conversation dives into how to identify a true mold problem using simple cues like what you can see, smell, and feel, along with insights on testing methods, humidifiers, VOCs, and finding the source of contamination. We also explore bigger-picture health topics including limbic retraining, the Cell Danger Response, and Jason's philosophy that optimal health comes down to “air, food, and attitude.” Jason Earle is a man on a mission. An adoring father of two boys, incurable entrepreneur and indoor air quality crusader, he is the founder & CEO of GOT MOLD?, and the creator of the GOT MOLD?® Test Kit. The realization that his moldy childhood home was the underlying cause of his extreme allergies and asthma, led him into the healthy home business in 2002, leaving behind a successful career on Wall Street. Over the last two decades, Jason has personally performed countless sick building investigations, solving many medical mysteries along the way, helping thousands of families recover their health and peace of mind. He has been featured or appeared on Good Morning America, Extreme Makeover: Home Edition, The Dr. Oz Show, Entrepreneur, Wired, and more.SHOW NOTES:0:40 Welcome to the podcast3:04 About Jason Earle4:03 Welcome him to the show!4:51 What happens when we use bleach on mold8:05 Bleach chemical composition12:36 Why you need to clean it, not kill it13:45 Mold in your toilet15:24 Mold growth vs a mold problem18:10 How much mold is too much?20:11 3 Steps: See, Smell, Feel22:08 Humidifier 10124:45 VOCs & Musty odors28:31 Air vs Dust sampling37:25 No false negative38:19 *CALOCURB*40:09 *APOLLO NEURO*42:15 Finding the source43:09 Self-directed Mold Assessment 46:40 Next-gen sequencing48:48 Mold sensor50:08 Mycotoxin testing58:09 Air on airplanes1:02:58 Looking for mold in a new home1:08:08 “Air, Food & Attitude”1:15:05 Limbic Retraining1:18:59 Cell Danger Response1:23:35 Where to find him1:24:52 Thanks for tuning in!RESOURCES:Calocurb - code: RENEE10Apollo Neuro - code: BIOHACKERBABESWebsite: GotMold?Get your test kitFREE E-BookIG: @gotmoldFB: GotMoldEp 227: Understanding Mold Exposure & RisksSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Are your relationships stealing your DNA? In this episode, Drs. James and Debra Rouse explore a landmark 2026 study showing that "Social Hasslers" accelerate biological aging by 1.5% annually. Key Discussion Points: The Life-Heist: Understanding how chronic friction frays your telomeres. The Dimmer Switch Metaphor: Why the body enters a defensive Cell Danger Response when you lack social safety. The Rouse 2-Hour Rule: A practical tool to measure your biological recovery time after social interactions. Clinical Resets: The role of peptides like MOTS-c and nutrients like PQQ in repairing mitochondrial damage. The Graceful Withdrawal: Why setting boundaries is a high-level act of biological self-respect.

In this episode of the Evolving Wellness Podcast, host Sarah Kleiner welcomes back Dr. Scott to discuss the 'sympathetic spiral of doom' and how modern lifestyles contribute to chronic stress and energy depletion. Dr. Scott shares insights into how overstimulation, poor diet, and interrupted sleep cycles can lead to nervous system dysregulation and mitochondrial dysfunction. The conversation covers the importance of circadian rhythm, hydration, and low-hanging fruit lifestyle changes to support overall wellbeing. They also explore the potential benefits of methylene blue, red light therapy, and other practical tools for regaining optimal health. Tune in to learn more about foundational steps to improve energy levels and break free from chronic stress.About Dr. ScottDr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions (a Smarter Not Harder company). His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and moreConnect with Dr. Scott - https://www.linkedin.com/in/drsherr/ _________Sponsored By:→ Bon Charge | Go to https://boncharge.com/products/demi-red-light-device?rfsn=8108115.26608d & use code SARAHKLEINER for 15% off storewide.→ VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/ → Organifi | For an exclusive offer, go to https://www.organifi.com/SARAHK for 20% off your order._________Timestamp:00:00 Introduction and Personal Experience with Coffee00:51 Welcome to the Evolving Wellness Podcast03:37 Understanding the Sympathetic Spiral of Doom06:29 The Role of the Nervous System and Mitochondria10:53 Practical Tips for Nervous System Regulation16:53 The Importance of Circadian Rhythm and Light Exposure25:31 Supporting Mitochondrial Health and Energy Production36:17 The State of Metabolic Health in the US36:55 Improving Mitochondrial Function37:27 Addressing Trauma and Sympathetic Overdrive38:31 The Importance of a Supportive Environment40:38 Sleep and Its Impact on Health44:35 The Role of Blue Blockers and Sleep Aids48:21 Caffeine and Its Effects on the Body50:46 The Benefits of Exogenous Ketones58:56 Navigating the Sympathetic Spiral of Doom01:05:14 Final Thoughts and Resources——— This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJIFree Webinar on Light & Health (includes free light bulb guide) - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarGet Early Access to Podcast Episodes & my Seasonal Food Course + UVB+Red Light Therapy course for free -  https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Today, I'm joined by the thoughtful Dr. Clement Lee, a naturopathic doctor blending ancient wisdom from Chinese medicine with cutting-edge regenerative therapies. In this episode, Dr. Lee gets real about why people can feel deeply unwell long before anything shows up on standard labs—and how subtle issues like limbic system stress, toxins, and chronic inflammation quietly undermine our vitality.   Episode Timestamps: Welcome and episode overview ... 00:00:00 Prolotherapy, Chinese medicine, and complex healing cases ... 00:05:16 Common misconceptions in chronic illness treatment ... 00:13:15 Why mindset and the limbic system affect healing ... 00:18:02 Early warning signs of chronic illness ... 00:22:50 Evaluating toxins, hormones, and inflammation in root cause medicine ... 00:26:03 Toxic overload concerns in children ... 00:27:09 First steps for chronic, hard-to-treat cases ... 00:31:56 Top interventions for longevity now ... 00:33:43 Testing for heavy metals and toxins ... 00:35:12 Inflammation loops and surprising causes like mold ... 00:38:12 The role of cellular healing and the nervous system ... 00:47:09 Advanced therapies: peptides, IV nutrients, and more ... 00:52:01 Mast cell activation and immune overdrive signals ... 01:08:23 Key takeaways and easy strategies for stress ... 01:26:40   Our Amazing Sponsors: Mitopure Longevity Gummies by Timeline — Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure Gummies.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Youth Daily by Young Goose — An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours at younggoose.com and use code Nat10 for first orders or 5NAT for returning customers.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Dr. Bill Lawrence Episode

Why You Should Listen:  In this episode, you will learn about the role of Body Ecology in Candida, Long COVID, viral illness, and autism. About My Guest: My guest for this episode is Donna Gates.  Donna Gates, MEd, ABAAHP is a pioneer in gut health, infections, and immunity.  Decades before it became mainstream, she was the first to teach about the extraordinary and complex world inside the gut, now known as the microbiome, and how it influences immunity, brain health, metabolism, and long-term wellness.  She is the founder of Body Ecology, a revolutionary system that introduced the first gluten-free, sugar-free, and dairy-free nutritional approaches, with a strategic focus on specific fermented foods to create a thriving inner ecosystem in the gut.  In her bestselling book, "The Body Ecology Diet", which has remained relevant for decades, Donna explains how to conquer Candida, restore microbial balance, and rebuild the immune system.  She reveals how the inner ecosystem is established at birth and how this process represents nature's original form of building a vibrant immune system.  By partnering with nature, rather than attempting to override it, we build true immune resilience, even in a toxic world where pathogens are a constant threat.  Her newest book, "Taming the Dragon: Body Ecology's Guide to Preventing and Treating Viral Infections", offers practical solutions for persistent viral illness, immune dysfunction, and long-haulers. Key Takeaways: What is the Body Ecology diet? What strategies can support optimizing Candida and the inner ecosystem? Can fermented foods be used in those with MCAS? How are conditions such as SIBO and SIFO approached? What was Donna's personal journey with Long COVID? What tools has Donna found helpful for regaining her health after COVID? How did SOT help Donna move past Lyme disease? What is the impact of spike proteins and how might they be mitigated? How can vascular health be optimized in the era of COVID? What strategies can support a robust immune system and minimize immunosenescence as people age? What role do chronic viruses have on health? Is it more important to boost or to modulate the immune system? How does the Cell Danger Response fit into the chronic illness discussion? What are some strategies for supporting the vagus nerve? What dietary changes are important when dealing with a viral condition? How do acidity and alkalinity play a role? What are some strategies for supporting detoxification? What has Donna seen over many years of working with children with autism? What is the Epigenetic Reset? Connect With My Guest:  BodyEcology.com Related Resources: Book - Taming the Dragon: Body Ecology's Guide to Preventing and Defeating Viral Infections An Antiviral Diet Interview Date: January 29, 2026 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode228. Support the Show: To support the show and Buy Me a Coffee, visit https://betterhealthguy.link/BuyMeACoffee. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Are you eating clean, training smart, managing stress — maybe even using hormone replacement — but still struggling with fatigue, inflammation, stubborn weight, low energy, or poor recovery?

Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity. Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes. You'll Learn: • What the Cell Danger Response is and how it reshapes aging and performance • How mitochondria sense stress before symptoms appear • Why cellular energy controls resilience, sleep, and longevity • How methylene blue supports mitochondrial electron flow • Why fasting and ketosis shift metabolism between repair and growth • How travel, light, and circadian disruption affect aging • Why very low LDL can impair detoxification and immune signaling • Why real anti-aging starts at the cellular level, not with disease labels Thank you to our sponsors! AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. Screenfit | Get your at-home eye training program for 40% off using code DAVE at www.screenfit.com/dave. Puori | Use code DAVE at puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cell danger response podcast, mitochondria aging, mitochondrial dysfunction aging, health optimization medicine, dr ted achacoso, boomer anderson, troscriptions, troscriptions methylene blue, methylene blue mitochondria, methylene blue biohacking, cellular aging podcast, anti aging mitochondria, metabolic stress aging, fasting ketosis metabolism, mitochondrial energy production, neuroplasticity mitochondria, sleep optimization aging, functional medicine mitochondria, smarter not harder biohacking, dave asprey mitochondria Resources: • Get A Discount On All Troscription Products with code ‘dave' at: https://troscriptions.com/ • Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/ • Discover More About The ‘Health Optimization Medicine and Practice' From Our Guests: https://homehope.org/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:25 – Introduction & Guest Background 3:11 – Health Optimization Medicine Origins 4:26 – Root Causes of Health vs Disease 6:15 – Biohacking & Self-Experimentation 8:19 – Medicinal Plants & Nootropics 11:25 – Travel & Jet Lag Solutions 13:42 – Cell Danger Response 17:38 – Metabolites & Cellular Health 18:57 – LDL & Lipopolysaccharides 20:42 – Cellular Model & First Principles 22:55 – Consciousness & Mitochondria 25:46 – Nanotechnology Research 28:55 – Giving Back & Service 31:17 – Blue Cannatine Development 34:48 – Methylene Blue Products 36:22 – Metformin Discussion 38:00 – Dosing & Cordycepin 41:25 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if fine lines, breakouts, and flare-ups are not just skin issues, but the body replaying old experiences it never got to resolve? In this episode, we explore how nervous system patterns, unresolved emotion, and the way we hold stress in the body can quietly shape how our skin ages over time. We look at the skin as a boundary, a canvas, and a reflection of how safe we feel in the world.We talk with practitioner Eva Hooft about psychosomatics, face mapping, and the cell danger response, and how a chronically dysregulated system keeps inflammation and premature aging on a loop. Eva explains how somatic work can shift bowel function, circulation, and visible radiance, and why she often sees the liver and drainage as the missing link in chronic skin problems. We also dig into mineral balance, heavy metals, community, and why sustainable protocols have to respect both physiology and emotion.Eva Hooft is a somatic and detox practitioner who combines nervous system work, subconscious reprogramming, and mineral-based detox to help clients unwind chronic symptoms from the inside out. Through group programs, one-to-one work, and education, she guides people to build safety in the body, restore drainage, and release stored burdens so their health and skin can reflect a more regulated state.We Also Discuss:(00:54) How Unresolved Emotion Shows Up on the Skin(08:23) The Cell Danger Response and Chronic Inflammation(13:25) Somatic Practices That Shift Physical Health(19:41) Liver Congestion, Bowel Health, and Clear Skin(24:28) Mineral Balance, Heavy Metals, and Nervous System Stress(30:27) Community, Safety, and the Biology of Healing(34:27) Blending Subconscious Work with Detox Protocols(38:19) Botox, Natural Alternatives, and Sustainable BeautyFind more from Young Goose:Vampire Exosomes → Professional Exosome Serum for Regeneration and Post-Treatment Recovery Use code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Eva Hooft:Instagram: @eva.hooftWebsite: evahooft.com

Aging isn't just a number — it's biology in motion. In this deep-dive episode, Coach Debbie Potts breaks down how to rebuild your metabolism, restore cellular safety, and retrain your body to burn fat efficiently using the latest tools in metabolic science. Learn how your mitochondria, hormones, and nervous system work together — and what happens when they don't. Using insights from PNOĒ Metabolic Testing, AMPK/mTOR pathways, the Cell Danger Response, and vagus nerve regulation, you'll discover how to move from Metabolic Chaos® to Metabolic Harmony — the true foundation of fat loss, performance, and longevity. Inside this Episode PNOĒ Metabolic Testing: See exactly how your body burns fuel (fat vs. carbs) and pinpoint your FatMax zone. AMPK Activation: How to unlock your body's natural repair and fat-burning mode through training, fasting, and cold exposure. Cell Danger Response: Why your mitochondria hit the brakes — and how to tell them it's safe to produce energy again. Vagus Nerve Reset: Strengthen the "safety switch" that controls digestion, hormones, and inflammation. mTOR & Midlife Muscle: Reignite muscle growth and recovery through protein timing, strength training, and hormone balance. Cortisol & Hormones: Why chronic stress blocks fat loss — and how to restore your natural cortisol rhythm. The FutureYou Formula: PNOĒ + Functional Testing + Nervous System Reset = Metabolic Harmony. Key Takeaways You can't out-train a stressed-out nervous system — calm first, build later. Fatigue, stubborn belly fat, and slow recovery are signals of a body stuck in protection mode. Metabolic freedom comes from restoring safety, flexibility, and flow — not more restriction or cardio. Aging well is a skill you can train when you understand your metabolic blueprint. Ready to Rebuild Your Metabolism? Stop guessing and start testing. Schedule your PNOĒ Metabolic Test and Functional Review at www.DebbiePotts.net. Let's design your roadmap to thrive — not just survive — through midlife and beyond. Safety Note Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.

Your body is screaming for rest, but the moment you try to slow down, every alarm in your system goes off. Why does stillness feel like a threat?Because while you're chasing tangible solutions, your nervous system is running on an invisible map—one created when you were 3 years old. A map that says: the world is dangerous, don't let your guard down. And that map is keeping you sick.Most people don't realize that safety itself feels dangerous. The moment symptoms improve, you're waiting for them to come back. The moment you start to relax, panic sets in. This isn't self-sabotage. This is your nervous system operating on outdated programming—and it's triggering something called Cell Danger Response at the cellular level.In this episode, you'll discover:• Why your nervous system learned that feeling safe is actually dangerous—and how this contradiction is manifesting in your body right now• The unconscious "safety map" created between ages 0-7 that still dictates your healing capacity as an adult• How Cell Danger Response keeps your cells in defense mode, blocking detox, energy production, and healing—no matter what supplements you take• The survival strategies you developed (perfectionism, hyper-independence, people-pleasing) that saved you then but are destroying your health now• Why you can't think, supplement, or protocol your way out of nervous system dysregulation• The three pillars of true nervous system transformation: Awareness, Witnessing, and Integration• Why relational medicine (being seen and held by safe others) is more powerful than any biohack• How one woman raised her HRV from the 30s to the 90s in 90 days using this exact frameworkReady to experience what it feels like to be truly witnessed? Book a complimentary 30-minute Liber8 session at https://www.liber8.health/witness and discover what happens when your nervous system is held in safe presence.Connect with Raj:Newsletter – Sign up here: https://www.rajjana.com/staygrounded/Website: http://www.rajjana.com/Instagram: @raj_janaiTunes: https://podcasts.apple.com/rs/podcast/stay-grounded-with-raj-jana/id1318038490Spotify: https://open.spotify.com/show/22Hrw6VWfnUSI45lw8LJBPYouTube: https://www.youtube.com/@raj_janaLegal Disclaimer: The information and opinions discussed in this podcast are for educational and entertainment purposes only. The host and guests are not medical or mental health professionals, and their advice should not be a substitute for seeking professional help. Any action taken based on the information presented is strictly at your own risk. The podcast host and their guests shall have neither liability nor responsibility to any person or entity with respect to any loss, damage, or injury caused or alleged to be caused directly or indirectly by information shared in this podcast. Consult your physician before making any changes to your mental health treatment or lifestyle. Hosted on Acast. See acast.com/privacy for more information.

Are you struggling with hypothyroid symptoms like fatigue, weight gain, hair loss, or brain fog?  Have you been told the reason is that you have "low T3"? Many patients are told the solution is simple: add T3 thyroid hormone replacement. But is that the truth? Is that the correct strategy? In this Thyroid Answers Shorts episode, Dr. Eric Balcavage, functional medicine thyroid expert and host of the Thyroid Answers Podcast, explains: ✅ Why low T3 doesn't always mean you need medication ✅ How stress, inflammation, and the Cell Danger Response affect T4-to-T3 conversion ✅ Why simply adding T3 or desiccated thyroid may not fix your symptoms ✅ A new way to understand your thyroid labs through the Adaptive Thyroid Model™

Are you feeling stuck, inflamed, or frustrated that nothing seems to work anymore — even the so-called “miracle” GLP-1 medications? In this episode, Coach Debbie Potts explains why your metabolism probably isn't broken… it's misunderstood. Discover how PNOĒ Metabolic Testing and a Functional Health Investigation can reveal what's really driving your fatigue, weight gain, and burnout — and how to rebuild your metabolism naturally through The WHOLESTIC Method™ and your personalized FutureYou plan. You'll learn: What your breath can reveal about fat vs. carb metabolism How the Cell Danger Response shuts down energy production Why mitochondrial health is the key to longevity and vitality How sympathetic dominance and poor vagal tone block fat loss The balance between AMPK and mTOR for optimal aging Why VO₂ Max is one of the best predictors of longevity How to rebuild your health from the inside out — starting with drainage, detox, and nervous-system repair Why you can't out-supplement poor lifestyle habits or out-exercise a poor diet Debbie also shares how her clients use testing, not guessing, to identify their personal metabolic roadblocks — and how stacking consistent “base hits” with the Eight Elements of The WHOLESTIC Method™ leads to long-term transformation. Because aging isn't the enemy — unawareness is. ✨ Test your metabolism. Rebuild your energy. Redefine your Future You.

Your thyroid doesn't work in isolation. It relies on your liver, your bile, and even your gut bacteria to keep hormone conversion running smoothly. In this episode of Thyroid Shorts, Dr. Eric Balcavage explains how thyroid hormone T3 regulates bile acid production, shapes your microbiome, and keeps your gut lining strong in a state of homeostasis. But what happens when stress, inflammation, or the Cell Danger Response lower circulating T3? The liver shifts bile chemistry, gut bugs change, and your barrier can loosen. This isn't necessarily dysfunction — it's your body's intelligent defense mode. Short-term, it helps fight microbes and fuel the immune system. Long-term, it can leave you stuck with fatigue, bloating, constipation, brain fog, and “normal” labs that don't match how you feel. You'll also learn why giving T3 medication in this state can be both helpful and harmful — and why timing, context, and removing the underlying threats matter more than simply “optimizing” your labs. Key topics: How T3 regulates bile acid balance, gut microbes, and barrier function. Why low T3 shifts bile acids toward defense mode (↑CA, ↓CDCA). The adaptive purpose of sluggish bile and reduced conversion. The pros and cons of T3 replacement during inflammation. Clinical guardrails for restoring thyroid health without chasing numbers.   www.drericbalcavage.com

Why You Should Listen:  In this episode, you will learn about the latest approaches to healing your body from mold toxicity, Lyme disease, and other complex, chronic health conditions. About My Guest: My guest for this episode is Dr. Neil Nathan.  Neil Nathan, MD has been practicing medicine for over 50 years and has been Board Certified in Family Practice and Pain Management and is a Founding Diplomate of the American Board of Integrative Holistic Medicine and a Founding Diplomate of ISEAI. He has written several books, including "Healing is Possible: New Hope for Chronic Fatigue, Fibromyalgia, Persistent Pain, and Other Chronic Illnesses" and "On Hope and Healing: For Those Who Have Fallen Through the Medical Cracks."  He has been working to bring an awareness that mold toxicity is a major contributing factor for patients with chronic illness and lectures internationally on this subject which led to the publication of his eBook, "Mold and Mycotoxins: Current Evaluation and Treatment, 2016" (now updated to 2022), and then to his best-selling book "Toxic: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities and Chronic Environmental Illness."  2021 saw the publication of "Energetic Diagnosis," a discussion of the value of intuition and energetic devices as an aid to both diagnosis and treatment of medical illness.  In 2024, his book "The Sensitive Patient's Healing Guide" was released with a focus on how to approach the treatment of sensitive patients.  And most recently, in late 2025, the second edition of his book "Toxic" was released with several years of new information and insights on healing from complex chronic conditions.  Dr. Nathan has been treating chronic complex medical illnesses for 30 years now, and Lyme disease for the past 20 years.  As his practice has evolved, he finds himself increasingly treating the patients who have become so sensitive and toxic that they can no longer tolerate their usual treatments, and his major current interest is in finding unique ways of helping them to recover. Key Takeaways: Is Long COVID the Great Unmasker? Is POTS an underlying cause or is it a symptom? How might the Radiance Long Hauler testing be helpful? What supplements or botanicals may be helpful for those in a Cell Danger Response? Are hormones generally well-tolerated when one is in a Cell Danger Response? When might be the right time to introduce PC?  VIP? What are the more common sensitizers of a sensitive patient? What are the more common drivers of MCAS? What are some strategies for modulating the inflammatory response? Is MCS the same as MCAS? Should limbic retraining be more active? How often are mycotoxins seen in patients with Alzheimer's? Does HLA-DR impact a patient's recovery potential? How do you handle a suspected mold illness patient when their urine mycotoxin testing is negative? What is the best binder for mycophenolic acid?  Chaetoglobosin? Do the benefits of bentonite clay outweigh the potential risks? What is the source of gliotoxin in the body? How is the treatment of fungal colonization approached? What role have Actinobacteria and endotoxins played in treating patients? Can Bartonella be treated with natural antimicrobials alone? Does treating mold and Lyme improve EDS? Can secondary porphyria be an indication that the antimicrobial is working? What is the role of EMFs in chronic illness? How large of a factor are parasites? Do mold and Lyme contribute to ME/CFS, Fibromyalgia, autism, and PANS/PANDAS? What is the role of nitric oxide in recovering health? Connect With My Guest:  NeilNathanMD.com Related Resources: Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness Interview Date: September 29, 2025 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode223. Support the Show: To support the show and Buy Me a Coffee, visit https://betterhealthguy.link/BuyMeACoffee. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Are you stuck in "thyroid purgatory" - optimized labs but persistent symptoms? The missing piece might be emotional.   In this powerful conversation, Dr. Eric sits down with Licensed Professional Counselor and Board-Certified Art Therapist Kate King to explore the hidden emotional roots of thyroid dysfunction that conventional medicine completely ignores.   What You'll Discover: How ancestral trauma and intergenerational patterns literally encode themselves in your cellular metabolism Why your thyroid might be your body's intelligent way of protecting you from feeling too much The difference between managing stress and actually reprogramming your stress response patterns How the Cell Danger Response keeps your thyroid stuck in protection mode Practical steps to shift from emotional survival patterns to thyroid recovery Why accountability and inner work are as crucial as diet and supplements for healing And more... Kate King's experience is sourced from her 17+ year background as a Licensed Professional Counselor, Board-Certified Art Therapist, and award-winning author. As the founder and owner of The Radiant Life Project, Kate's mission is to help individuals heal their inner wounds so that they can positively contribute to the evolving collective. She teaches how to ignite your inner spark with psychology-based personal growth and relationship books, inspirational public speaking, creative consulting, and individual and group coaching. Kate's work is where psychology meets spirit, where creativity meets clarity, and where burnout meets renewal. Kate's impactful resources, tools, and practices provide an accessible entry point into a life of greater authenticity, fulfillment, and illumination. #ThyroidHealth #EmotionalHealing #AncestralTrauma #StressManagement #FunctionalMedicine #ThyroidRecovery #MindBodyConnection #Epigenetics #ThyroidPurgatory #CellDangerResponse   Connect with Kat: https://theradiantlifeproject.com   Connect with Dr. Eric:

Mitochondrial health is vital to your body's overall wellbeing and longevity. I've compiled the top treatments that can help you boost and activate your mitochondria if you suspect signs of dysfunction. From best foods, to natural supplements, alternative therapies and exercise, these are the best methods to help your mitochondria heal.    ✅Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

What if the popular narrative about trauma is incomplete? What if trauma isn't just a psychological phenomenon, but a fundamentally biological process that gets encoded in your cells, mitochondria, and nervous system? Dr. Aimie Apigian is a double board-certified physician in preventive and addiction medicine who's revolutionizing how we understand and treat trauma.  Her groundbreaking new book, "The Biology of Trauma," reveals the hidden physiological mechanisms behind trauma responses. In this conversation, she explains where traditional talk therapy falls short, how trauma creates a feedback loop of oxidative stress and cellular shutdown, and her innovative approach to healing trauma from the inside out, starting with cellular safety before diving into the emotional work.  

 Ever feel “stuck” with Hashimoto's, even when your labs look fine? This episode explores the Cell Danger Response (CDR): what it is, how it might keep your body in a protective mode, and why that can stall thyroid healing. You will know simple ways to start moving out of “danger mode” toward better energy and clarity. Connect With Me -Instagram - https://www.instagram.com/anshulguptamd/Twitter - https://www.twitter.com/anshulguptamdFacebook - https://www.facebook.com/drguptafunctPinterest - https://www.pinterest.com/anshulguptamdTo Buy Good Quality Supplements Goto -https://functionalwellbeingshop.com/Work With Me -https://www.anshulguptamd.com/work-with-me/Take The Thyroid Quiz & Evaluate Your Thyroid Health -https://www.anshulguptamd.com/thyroid-quiz/About Dr.Anshul Gupta MD -Dr. Anshul Gupta Md Is a Board-certified Family Medicine Physician, With Advanced Certification In Functional Medicine, Peptide Therapy, And Also Fellowship training in Integrative Medicine. He Has Worked At The Prestigious Cleveland Clinic Department Of Functional Medicine As Staff Physician Alongside Dr. Mark Hyman. He Believes In Empowering His Patients To Take Control Of Their Health And Partners With Them In Their Healing Journey.He Now Specializes As A Thyroid Functional Medicine Doctor, And Help People Reverse Their Unresolved Symptoms Of Thyroid Dysfunction.

In this special reverse interview episode, my friend and colleague Steven Wright from Healthy Gut interviews me about the core concepts from my upcoming book, The Biology of Trauma. Steven understands the somatic work, the parts work, the biology, the capacity, and the overwhelm from his own healing journey, making this conversation uniquely insightful. I share stories I haven't told anywhere else - including my keto diet disaster during surgery residency that became my first clue about the biology of trauma. We explore why I rewrote this book seven times, how I discovered I had all three major biochemical imbalances, and the painful decision to place my adopted son Miguel in a different home - the grief that ultimately led to my autoimmune diagnosis and this entire body of work. Key Topics & Timestamps [00:00] The Eight Drafts of the book: Dr. Aimie's journey as an author [04:12] Beyond ACEs Scores: Why we can become obsessed with our score  [08:36] Capacity is Everything: Understanding your nervous system's dynamic capacity  [13:47] The Biology Block: How Dr. Aimie discovered her own biology was sabotaging her trauma healing [21:55] The Pain Equation: When humans decide to change  [25:44] Perception vs. Reality: How we create mountains from molehills  [28:19] The Healing Timeline: Why trauma work doesn't have to be a lifelong journey [34:04] Safety First: The critical sequence for healing trauma without retraumatization [37:18] Stress vs. Trauma: The crucial distinction that changes everything [38:18] Miguel's Story: The heartbreaking adoption journey that changed Dr. Aimie Main Takeaways The Three-Legged Stool: True trauma healing requires addressing psychological, emotional, AND biological aspects simultaneously Biology Keeps You Stuck: Inflammation, oxidative stress, and biochemical imbalances create internal danger signals that perpetuate trauma responses Capacity Changes Moment to Moment: Your nervous system's capacity is dynamic and requires constant awareness, not just daily check-ins Perception Creates Your Reality: Your body responds to your perception of danger, not actual danger - making that molehill into a mountain The Right Sequence Matters: Creating safety must come before attempting to process trauma, or symptoms worsen Fast Healing is Possible: When addressing all three domains properly, healing happens faster than medication with only positive "side effects" Notable Quotes "If something makes you sick, that is not stress. Let's call it for what it is. That is your body having gone into a trauma response." "Our capacity is not being measured up against our reality, it's being measured up against our perceptions." "The pain of staying the same has to become so bad that we're willing to undergo the pain of change." "If their body had already felt safe, it would have already opened up all of this stuff and let all of these emotions and trauma go. It hasn't felt safe." Episode Takeaway Trauma healing doesn't have to be a lifelong journey. By understanding that trauma lives in your biology - not just your mind - and following the proper sequence of safety, support, then expansion, you can heal faster than traditional approaches suggest. The key is addressing all three aspects: psychological, emotional, and biological, rather than focusing on just one. Resources Related To This Episode Resources/Guides: Biology of Trauma book - Bonuses are available when you Pre-order now. Go Deeper With Dr. Aimie with The Biology of Trauma Book (available only until September 22nd): Guided Seeker: Get the Workbook + Mastercourse to go with the book - walking you through each chapter's key concepts Accelerated Implementer: Everything above + live half-day online group intensive with Dr. Aimie for implementation support Fast Track Professional: Everything above + one full day in-person with Dr. Aimie at her home to identify your biggest personal block to your next level of healing and regulation as a professional and guide for others  Foundational Journey - If you want to be guided through The Essential Sequence laid out in the Roadmap and the book, join me and my team for this 6 week journey into your inner world with practical somatic and parts self-practices to lay your foundation to do the deeper work safely. These are the daily practices I have found that change one's biology and health symptoms the fastest. Steven Wright - Healthy Gut - Learn more about Steven's gut-brain support products: HoloZyme™ digestive enzymes with dual-strain activation technology, Tributyrin-X™ for microbiome diversity and gut lining health, and HCL Guard™ for protein digestion support Related Episode: Episode 122: Shutdown Before Stress: The Misstep in Trauma Healing That Often Gets Missed Related YouTube Video: Shutdown Before Stress: The Misstep in Trauma Healing That Often Gets Missed | Dr. Aimie Apigian About Dr. Aimie Apigian Dr. Aimie Apigian is a double board-certified physician in preventive and addiction medicine who bridges the gap between Western medicine and somatic healing practices. After her own health crisis in 2014 while in medical residency, she discovered how stored trauma was affecting her biology. She has since dedicated her career to helping others understand and heal the biological impacts of trauma through her courses, clinical practice, and her new book "The Biology of Trauma."   Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. Comment Etiquette: I would love to hear your thoughts on this episode! Please share your constructive feedback by using personal name or initials so that we can keep this space spam-free, and let's keep the discussion positive!

If you're taking thyroid medication but still struggling with fatigue, brain fog, and weight gain despite "perfect" lab results, this episode will change everything. Dr. Eric Balcavage reveals why millions of thyroid patients are stuck in "Thyroid Purgatory" - where labs look optimal but symptoms persist - and introduces the groundbreaking concept of cellular hypothyroidism that explains why your cells may be rejecting the thyroid hormones you're taking.   Discover why the Cell Danger Response acts like a cellular security system, blocking thyroid hormone utilization even when blood levels are perfect. Learn why increasing medication doses often makes people feel worse, not better, and understand the real solution to breaking free from thyroid treatment frustration. What You'll Learn: Why "perfect" thyroid labs don't guarantee you'll feel better The Cell Danger Response and how it blocks thyroid hormone utilization Why cellular hypothyroidism is the missing piece in thyroid treatment How chronic stressors keep your cells in protection mode Why increasing T3 or switching medications often backfires The difference between thyroid management and true thyroid recovery Which cellular stressors might be sabotaging your treatment The Strategic Thyroid Solution approach to addressing root causes Real patient stories of breaking free from Thyroid Purgatory Perfect for: Thyroid patients frustrated with persistent symptoms despite treatment, those considering medication changes, anyone struggling with both hypothyroid and hyperthyroid symptoms, and healthcare practitioners seeking a deeper understanding of thyroid hormone resistance. Resources Mentioned: Free Thyroid Assessment: drericbalcavage.com Thyroid Recovery Blueprint Hashtags: #ThyroidShorts #CellularHypothyroidism #ThyroidRecovery #ThyroidPurgatory #CellDangerResponse #ThyroidMedication #Hypothyroidism #ThyroidHealth #FunctionalMedicine #ThyroidHormones #T3Resistance #ThyroidTreatment #ChronicFatigue #BrainFog #ThyroidSymptoms #HealthPodcast #DrEricBalcavage #StrategicThyroidSolution #ThyroidAnswers #ThyroidSupport   Contact info: www.drericbalcavage.com Emaill: info@drericbalcavage.com IG: drericbalcavage  

Stuck in Survival Mode?  If you're feeling exhausted, inflamed, foggy, and dismissed—despite doing “all the right things”—this episode is your missing piece. Today on The Coach Debbie Potts Show, I'm breaking down what's really behind the growing wave of unexplained chronic symptoms—and why standard labs and protocols just aren't cutting it. We'll explore: ✅ What CIRS (Chronic Inflammatory Response Syndrome) really is—and how it's far more than just a mold problem ✅ Why the Cell Danger Response keeps your body locked in defense mode ✅ How vagal nerve toxicity disconnects your brain from your gut, hormones, and detox pathways ✅ The overlooked role of low stomach acid in immune dysfunction ✅ Why your symptoms are signals—not random—and how to start healing from the cell up If you're stuck, sensitive, and overwhelmed—but deep down you know something is still off—this episode will help you start putting the missing pieces together.

In this episode, Dr. Eric Balcavage responds to a thoughtful viewer comment that challenges key aspects of his adaptive thyroid physiology model and Cell Danger Response theory. This deep-dive discussion addresses whether his approach applies to every hypothyroidism case, clarifies the 71% improvement statistic, and explores the role of T3 therapy in thyroid treatment.   Key Topics Covered: Does the Cell Danger Response theory apply to all hypothyroidism cases? Clarification of the 71% patient improvement statistic - what it really means Historical use of NDT (Natural Desiccated Thyroid) and treatment evolution Post-Graves disease thyroid management and receptor sensitivity Why T3 therapy works for some patients but doesn't restore physiology The difference between symptom management and true thyroid restoration When to consider alternative approaches for treatment-resistant cases Dr. Balcavage provides nuanced responses while acknowledging the limitations of current thyroid models, emphasizing that his approach offers hope for patients who haven't found success with conventional T4, NDT, or T3 protocols.   Perfect for: Thyroid patients stuck in "thyroid purgatory," healthcare practitioners seeking new perspectives, and anyone interested in understanding why standard thyroid treatments sometimes fail.

#166  - Beyond Functional Medicine: Why Most Health Experts Can't Help Complex Chronic Illnesses with Mel Hopper Koppelman   What if your chronic complex health issues aren't about needing more supplements or a new practitioner… but from a nervous system that's been stuck in survival mode since childhood? In this episode of Pretty Well, I'm joined by Mel Hopper Koppelman—an expert in neurological healing who's helping patients finally get better after functional medicine has failed.  We talk about the overlooked role of retained primitive reflexes, how childhood stress rewires adult health, and why your gut might still be leaky decades later (hint: it started long before gluten showed up). Mel breaks down why some people never fully heal from chronic fatigue, autoimmunity, mold toxicity, and even trauma—and what to do about it. You'll learn about the Cell Danger Response, what it means to truly “regulate your nervous system,” and why green smoothies might not be doing you any favors. Mel also unpacks in detail the 4 Stage Process of Recovering from Complex Chronic Health Issues.  If you've ever felt like you're doing all the right things and still not getting better, this episode might flip everything you thought you knew about healing.   Connect with Mel: Website https://essays.synthesishealth.co/mel-hopper-koppelman/ Social https://www.instagram.com/synthesishealth.co/  https://www.facebook.com/melkoppelmanacupuncture    Join the conversation: Share your thoughts with us on social media or in the comments! Subscribe, Share & Review: 

 Understanding CIRS, Mitochondria & the Cell Danger Response" In this solo episode, I dive deep into one of the most overlooked root causes of chronic fatigue, brain fog, and hormonal imbalances: Chronic Inflammatory Response Syndrome (CIRS) and how it connects to mold, toxic burden, and mitochondrial dysfunction. You'll learn: What CIRS is and why it's often misdiagnosed How mold and MARCoNS infections block your hypothalamus and trap your body in survival mode Why chronic illness often begins with the Cell Danger Response (CDR) How mitochondria, Free T3, and the gut-brain barrier are all connected

Explore the link between fatigue, mitochondrial health, and chronic illness with Dr. Bryan Rade. Learn how mold, stress, infections, and nutrient depletion impair cellular energy—and how to recover.Dr. Jen Pfleghaar speaks with Dr. Bryan Rade, a leading naturopathic doctor specializing in chronic illness, about one of the most overlooked causes of fatigue: mitochondrial dysfunction. In this episode of The Integrative Health Podcast, they unpack why your energy issues might not be about thyroid or hormones, but about your cellular powerhouses failing to produce energy efficiently.Dr. Rade breaks down what mitochondria are, how they fuel your brain, muscles, and liver, and the common stressors that damage their function, including mold, chronic infections, nutrient depletion, and insulin resistance. He shares powerful insights into the Cell Danger Response and why persistent fatigue often signals deeper, unaddressed issues.You'll learn how to optimize mitochondrial function with targeted nutrients, hormone balance, and environmental detox—and hear patient stories of energy breakthroughs using a comprehensive mitochondrial support formula.If you feel “mostly fine” but not quite thriving, this episode is for you.Dr. Bryan Rade, ND, is a licensed naturopathic doctor specializing in complex chronic illness. He has developed a comprehensive approach to treating fatigue by restoring mitochondrial function through environmental detox, targeted nutrient therapy, and hormone balancing. Dr. Rade is also the host of the Overcoming Chronic Illness podcast and creator of an in-depth online course to guide patients through the maze of chronic conditions.Instagram: https://www.instagram.com/dr.bryanrade.nd/?hl=en Facebook: https://www.facebook.com/bryan.rade/ PODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavorites FOLLOW ME:Instagram :: https://www.instagram.com/integrativedrmom/Facebook :: https://www.facebook.com/integrativedrmomYouTube :: https://www.youtube.com/@integrativedrmom FTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you). I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored. DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only. For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

This episode is brought to you by Fatty15, Pique, and Strong Coffee. Neuronutritionist Timothy Frie joins us today to delve into the intricate connections between dietary choices, trauma, and brain health. Tim shares his expertise on how our eating behaviors are often unconsciously shaped by past trauma, stress, and grief, emphasizing the importance of neuro nutrition in healing and recovery. The discussion highlights the transformative power of the MIND diet, which integrates Mediterranean and DASH dietary principles, to enhance mental well-being. We explore the challenges faced by individuals with chronic illnesses and mental health conditions, focusing on the nutritional needs of the brain and nervous system. Key topics include the Cell Danger Response, the impact of protein and micronutrient deficiencies, and the role of neuroplasticity in trauma recovery. The episode underscores the significance of personalizing nutrition to support cognitive function and overall well-being, advocating for a varied and colorful diet to optimize mental health. Follow Tim @timothyfrie Follow Chase @chase_chewning ----- In this episode we discuss... (00:00) Understanding Nutrition's Impact on Brain Health (13:19) Nutrition's Role in Brain Function (18:35) Neuronutrition and Traumatic Stress (22:35) Cell Danger Response and Health Challenges (28:21) Nutrition, Brain Health, and Wellbeing (37:05) Protein Deficiency's Impact on Cognitive Function (43:11) Neuroinflammation and Nutrient Deficiency (47:40) Nutrition, Trauma, and Stress Impact (57:55) Understanding Trauma, Neuroplasticity, and Nutrition (01:05:35) Trauma, Therapy, and Neuroplasticity (01:17:36) Supplementation and Trauma (01:24:41) Exploring Neuro Nutrition and Curiosity ---- Episode resources: Save 20% for life on organic teas and drinks at https://www.PiqueLife.com/everforward Save 15% on C15:0 essential fatty acids with code EVERFORWARD at https://www.Fatty15.com/everforward Save 15% on organic lattes and coffee with code CHASE at https://www.StrongCoffeeCompany.com  Watch and subscribe on YouTube Learn more at TimFrie.com

What if healing didn't start with supplements, but with a shift in thought? In this episode of the Smarter Not Harder Podcast, Dr. Scott Sherr sits down with renegade nurse and educator Karen DiMarco to explore how psychosocial stress, identity, and hypervigilance can create—or dissolve—chronic illness. Karen shares her personal health journey, the groundbreaking chronic fatigue study she co-led, and why our thoughts may be the most overlooked variable in healing. Join us as we delve into: The story behind Karen's recovery from chronic fatigue syndrome Her radical 8-week study that helped patients recover—without meds or supplements The connection between thought, oxidative stress, and the cell danger response How metaphors and insight can rewire the brain and physiology This episode is for you if: You've struggled with chronic illness and feel stuck You're curious about the mind-body connection in healing You're a health professional working with complex, hard-to-treat patients You want to learn how to “collapse the gap” between who you are and who you think you should be You can also find this episode on… YouTube: https://youtu.be/RAdH75quOzM Find more from Karen DiMarco: Website: https://karendimarco.com/home/ RNegade.pro: https://rnegade.pro/ LinkedIn: https://www.linkedin.com/in/karen-dimarco-rnegade/ Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

What if your fatigue, brain fog, or chronic symptoms aren't a malfunction—but a misunderstood survival mechanism? In this episode, you'll learn... What the Cell Danger Response is and why it's triggered by infection, trauma, or toxins. Why your body might be stuck in survival mode—and how that explains persistent fatigue, pain, or brain fog. How mitochondria signal danger and what it means when ATP becomes an alarm. The three phases of CDR: Defense, Repair, and Reintegration—and what it takes to move forward. How healing involves safety, not force: through trauma work, detox, red light therapy, and mitochondrial support. A hopeful framework for chronic illness that connects the dots between autoimmune disease, long COVID, autism, and more ------  0:00 Introduction 1:15 Cell Danger Response 2:48 ATP Release Issues 5:38 Phase 1: Danger Detection 8:07 Phase 2: Cell Defense 9:10 Phase 3: Recovery & Healing 9:55 Job of Mitochondria 11:10 Biggest Symptoms of CDR 13:10 Common Conditions Linked to CDR 16:52 Bloodwork Ad 18:12 Steps to Healing from CDR 35:10 Outro ------  Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. Follow Dr. Josh Axe Instagram Twitter Facebook TikTok Website ------  Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get:  Holistic health news & life-hacks from a biblical world view Powerful free resources including classes, Q&As, and guides from Dr. Axe The latest episodes of The Dr. Josh Axe Show Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe Links:  https://aonm.org/wp-content/uploads/2021/07/Cell-Danger-Response-IHCAN.pdf https://www.youtube.com/watch?v=u028TAyB9S4 https://pmc.ncbi.nlm.nih.gov/articles/PMC10427836/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6627909/ https://tacanow.org/family-resources/medical-article-common-medical-issues/the-cell-danger-response-in-autism/ https://www.sciencedirect.com/science/article/pii/S1567724919302922 https://www.sciencedirect.com/science/article/pii/S1567724918301053 https://www.sciencedirect.com/science/article/pii/S1567724913002390 https://www.sciencedirect.com/science/article/abs/pii/S0028390815002129 https://watermark.silverchair.com/gkv1003.pdf https://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30428-X https://www.sciencedirect.com/science/article/abs/pii/S0022356524183231 https://www.sciencedirect.com/science/article/pii/S1567724918301053 https://www.pnas.org/doi/abs/10.1073/pnas.1607571113 https://www.mdpi.com/2079-7737/8/2/27 https://pmc.ncbi.nlm.nih.gov/articles/PMC11336094/ https://pubmed.ncbi.nlm.nih.gov/39495479/ https://advancedbrain.com/blog/the-listening-program-safe-signal-cell-danger-response/ https://ncintegrative.org/wp-content/uploads/2024/06/Cell-Danger-Response-KING.pdf https://www.nature.com/articles/s41433-024-03091-4 https://pmc.ncbi.nlm.nih.gov/articles/PMC7735836/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5859128/ https://pmc.ncbi.nlm.nih.gov/articles/PMC4988248/ ------  Ads: Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at https://beyondbloodwork.com/

Episode Highlights With Cathleen KingHer journey with mysterious symptoms and what finally helped her healWhat the cell danger response is, and why we have to understand this Her realization and paradigm shift to find the common denominator behind her health problems How she slowly “walked herself out of hell” and healedThe body is infinitely capable of healingIt is figuring out what is blocking, what is keeping the body from healing What happens if the signal that the threat hasn't passed is sent to the bodyThe programming to break to be able to send a safety signal to the bodyHow to learn to coexist with your diagnosis and lab tests in order to turn off cell danger response Creating the hypothesis that the body can heal itself and discard the information that has made you distrust your bodyYour belief system is your biggest ally in healing How to build nervous system resiliency without having a disproportionate response to triggersHow to use certain breathing practices to encourage the parasympathetic nervous system: box breath or 4-7-8 breathing You have to believe that it is safe to feel safe What vagus nerve training isLimbic and nervous system retraining to climb out of cell danger responseBrain retraining as a way to target the limbic system and amygdala to healResources We MentionPrimal TrustFree Primal Trust™ Guide to Self-Healing