Podcasts about ctp

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Best podcasts about ctp

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Latest podcast episodes about ctp

Anaheim Calling: for Anaheim Ducks fans
Zegras Hot Streak, Ducks Coaching Candidates, New Second Line

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Jan 24, 2023 96:51


On this episode, we discuss Trevor Zegras's recent hot streak, Anaheim's new second line, a full list of Ducks' potential coaching candidates, and much more. Enjoy! Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpodSubscribe to our live Twitch stream twitch.tv/crashthepondBecome a Patreon patron: patreon.com/crashthepondCheck out the video version of the podcast: youtube.com/crashthepondOr leave us a review on Apple PodcastsThanks for listening!

Anaheim Calling: for Anaheim Ducks fans
Zegras Back to Center, Henrique Potential Fit in Edmonton, Fowler Trade Rumors

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Jan 17, 2023 86:34


On this episode, we recap the Ducks-Penguins matchup, including line changes from Dallas Eakins that placed Trevor Zegras back at center. We also discuss if Adam Henrique to Edmonton makes sense, and also break down the Cam Fowler trade rumors. Enjoy!Support the show:Get 10% OFF tickets with promo code "CTP" at 714tickets.comSubscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Climbing The Pocket
Vikings vs Giants | The Final Score

Climbing The Pocket

Play Episode Listen Later Jan 16, 2023 51:53


On the Final Score today… It is Wild Card weekend and your Minnesota Vikings are taking on the New York Giants at US Bank Stadium. After a week of disrespect by the national media and especially the New Media being called things like frauds, illegitimate, more money going on the Giants, and even the crowd being called out for being too nice and not loud, the Vikings have the opportunity to use it as fuel and prove the haters wrong, once again. So far in the game, the Vikings started hot with an opening drive and then went silent until near half. Ed Donatell's defense looks like the same ol'-same ol' and the Giants have been scoring almost at will. Can the Vikings pull out another come-from-behind win again? Vikings are driving though. It ended up not being enough as the Vikings season ended with 31-24 loss to NYG. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations and celebrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. On today's show, we have Jonas, Jason, Flip, and Dave riding live with you in the final two minutes. Fan with us!!! Guest Jonas Stärk @JonasStaerk and maybe Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/CWj9P15_NJ8 At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
McTavish vs. Zegras Debate, Lineup Changes, Ducks Goalie GOAT Rankings

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Jan 10, 2023 93:03 Very Popular


On this episode, we discuss the Ducks' recent lineup changes that have Mason McTavish as the first-line center and Trevor Zegras as a winger on the second line, and what it might say about how the team views both players. We also touch on possible off-season moves, who the Ducks' greatest goalie of all time is, and much more!Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpodSubscribe to our live Twitch stream twitch.tv/crashthepondBecome a Patreon patron: patreon.com/crashthepondCheck out the video version of the podcast: youtube.com/crashthepondOr leave us a review on Apple PodcastsThanks for listening!

Climbing The Pocket
Vikings at Bears | The Final Score

Climbing The Pocket

Play Episode Listen Later Jan 8, 2023 40:02


On the Final Score today… It is the final game of the regular season and your Minnesota Vikings are looking for their 13th win. Will they get it? Absolutely! They started out with a 16-6 lead at the half which could've been a lot more if it weren't for a couple of key mistakes. Justin Jefferson went over 1,800 yards for the season. In the second half, starting players have been pulled and backups are getting some playing time. We are seeing the likes of Venderian Lowe and Kyle Hinton in for Christian Darrisaw and Ezra Cleveland. Keen Nwangwu gets some RB snaps and even Jalen Reagor caught a pass so far and 2 total. At the end of 3 quarters, the Vikings lead still by 10 points, 23-13. Will they keep pressing to get the W? They did with the backups even. Joseph then hits a 53-yarder to make it 26-13. What are your thoughts on the game so far? They won! Do you like that the Purple by defeating the Chicago Bears, is keeping the heat on the 49ers? Yes. The #3 seed in the NFC playoffs is a lock, but the #2? Maybe? We will see. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations and celebrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. On today's show, we have Jonas, Jason, Matt, Tyler, and Dave riding live with you in the final two minutes. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk and maybe Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/mINvRtRKAbk At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Treasury Career Corner
The Importance of a Personal Brand with Lee-Ann Perkins & Joel Campbell – Feature Episode

The Treasury Career Corner

Play Episode Listen Later Jan 3, 2023 58:35


In this extra special episode, I am joined by not one but TWO amazing previous podcast guests, Lee-Ann Perkins, the Assistant Treasurer at Specialized Bicycle Components, a global leader in the high-end bicycle and bicycle components business and Joel Campbell, the Chief Financial Officer of TreviPay, the global B2B payments and invoicing network, based in Overland Park, Kansas. In this episode, we discuss the importance of having a strong personal brand and how to network effectively to ensure that you are successful in your career. Whether you have just started working in your chosen career path, you're climbing the ladder, or even changing fields, do you ever feel that you need or can offer others a little professional help? This podcast is the perfect opportunity to hear from two industry experts on how networking and developing their personal brand has been a vital cog in their success journey. Achieving career success is about what you have done well, but also just as much about those who have partnered with you, helped you, guided you, and lifted you up along the way. Hear how our guests have benefited from being mentored and becoming mentors and how networking and personal branding have helped them land these mutually beneficial opportunities. Your network is your NETWORTH. The conversation is focused on the importance of building your network and the steps and habits that help you move outside of your comfort zone to build and strengthen your network. You can create a BRAND in minutes and destroy it in seconds. Learn from our guests as we discuss the importance of carving your path and developing your own personal brand. Know your assets, develop them, put them into practice and become known for your strengths. Lee-Ann Perkins Lee-Ann Perkins, CTP(CD), FCT is the Assistant Treasurer at Specialized Bicycle Components, a global leader in the high-end bicycle and bicycle components business. Originally from South Africa, she received her bachelor's in Management Accounting before moving to the USA on expat assignment with her husband. She obtained an MBA with honours and, due to a continued interest in compliance and governance, Lee-Ann completed the inaugural Financial Compliance Certificate through Chicago-Kent Law School in 2016. In 2021 she was awarded the FCT fellow designation with merit from the Association of Corporate Treasurers in the U.K. Lee-Ann holds the Association of Finance Professionals (AFP) CTP and CTP (CD) Canadian certifications and is recognized as a Subject Matter Expert by the AFP serving on the CTP exam formulation committee since 2008. Lee-Ann has been a member of the AFP Treasury Advisory Group since 2017 and is a current Advisory Board member for NACHA. She has served on the Houston Treasury Management Association Board as President & Chairman and held various other committee roles over the years. Lee-Ann has been a Treasury practitioner for 18 years and held roles in increasing authority in Publicly traded Oil and Gas and construction industries. Joel Campbell Joel Campbell is Chief Financial Officer of TreviPay, the global B2B payments and invoicing network, based in Overland Park, Kansas. He leads the company's Finance, FP&A, Accounting, Treasury, and Facilities & Procurement functions, with primary focus on managing all financial aspects of the business and the relationship with its private equity ownership team at Corsair...

Climbing The Pocket
Vikings at Packers | The Final Score

Climbing The Pocket

Play Episode Listen Later Jan 2, 2023 47:38


On the Final Score today… It is January 1, 2023, and the perfect time to start an annual of beating the Green Bay Packers. Happy New Year everyone! Your Minnesota Vikings have traveled to Wisconsin to renew the tradition of sweeping our biggest border rivals. The first half has been brutal and the Vikings trail at half 27-3. Same at the end of the third, but the Packers scored starting the 4th quarter to make it 34-3. They have been behind by more and have come back, but can they do it today? Absolutely not. The final score ended up being Packers 41-17 over the purple. The Packers have shut down, Jaire Alexander in particular doing the smothering of Justin Jefferson all day so far. Kirk Cousins has thrown numerous interceptions, but mostly not his fault. One of them returned for a touchdown in a crazy start to this game. Will it get better in the second half? No, of course it didn't. We will have to see. …And we saw. The Vikings drop to 12-4 and the #3 seed in the NFC Playoff picture. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations and celebrations. It looks like it's time to vent. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. On today's show, we have Jonas, Jason, Flip, and Dave riding live with you in the final two minutes. Did you like what you saw? Fan with us!!! Guest Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/lLTePeNtZcY At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
Dostal and McTavish Continue to Shine. Ducks Penalty Troubles

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Dec 27, 2022 89:36


On this episode, we discuss the Ducks last week of games, covering standout performances from Lukas Dostal and Mason McTavish, penalty trouble holding the team back, and much more. Enjoy the podcast, and happy new year!Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpodSubscribe to our live Twitch stream twitch.tv/crashthepondBecome a Patreon patron: patreon.com/crashthepondCheck out the video version of the podcast: youtube.com/crashthepondOr leave us a review on Apple PodcastsThanks for listening!

Climbing The Pocket
Vikings vs Giants | The Final Score

Climbing The Pocket

Play Episode Listen Later Dec 24, 2022 33:30


On the Final Score today… The Whiteout is full effect and your Minnesota Vikings are coming off of their big emotional comeback victory last week, and for most of this game seem a little dull. It is at the end of the third-quarter and the trail the New York Giants 13–10 after opening the game with a 10–0 lead, the Vikings defense looks to be returning to its old self , and that's not a good thing. But they did get some key plays. Will the defense step up in the fourth quarter? For the most part. Will this be another comeback win for Kirk Cousins? It was, making 8 for this season and tying the NFL record. Does Justin Jefferson get enough catches to break the hundred yard mark again? He did for 133. We'll find out! And we did. Join us in those final two minutes. Hopefully we cheer on a victory and don't have to vent today on Christmas Eve. Your Vikings now have a 12-3 record so let Vikings and holiday cheer begin! All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations and celebrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Flip, Tyler, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/ONps0FF_6OE At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Take That, Smartypants!
2023 OP Plan$ for KeyForge - Excited?

Take That, Smartypants!

Play Episode Listen Later Dec 23, 2022 13:10


At KeyForge Celebration, CTP of GG shared a broad overview of pretty ambitious OP plans for 2023. I'm excited, are you?

Climbing The Pocket
A Moment of Reflection | Fifteen Minutes⏱️ with Flipmazzi

Climbing The Pocket

Play Episode Listen Later Dec 21, 2022 27:54


On this episode of Fifteen Minutes⏱️ with Flipmazzi - It's time for an FMF Special when Flip texts you and says he wants to do one. Flip wants to take a moment of reflection. Your Minnesota Vikings come off of a truly historic come-from-behind victory over the Indianapolis Colts. In the game, there were many players that stepped up. They had to. It was a struggle that took everyone, not just on the field, but the fans in the stands cheering to build momentum and to power the Vikings to victory. In that, they won the NFC North Division crown for the 2022 season. As it sits right now, they are the #2 seed in the NFC playoffs. The worst they can do is fall to the #3 seed. The best would be to win the NFC's #1 seed, but that would require the Philadelphia Eagles to lose out. That is unlikely, but we can all hope. Join flip as he discusses these points below in this FMF special edition. 1. The Turning Point 2. The Unsung Heroes  3. Playoff Expectations  4. Next Man Up Next up… Beat the New York Giants. Fan with us!!! Flip Mazzi @Flipmazzi and a spot by producer Dave @Luft_Krigare as part of a @Climb_ThePocket Network's & @DailyNorseman's production. Also, with our newest partner at CTP, Lake Monster Brewing @LakeMonsterBrew as we venture beneath the surface in search of something unknown and extraordinary. This is in their wonderful beverage selections and our coverage of your favorite team. And if you are into some rocking wood art, check out That's Bad Ass Wood Art at @thatsbadassmn. __________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/aAhuYVQJq6M At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
Ducks Winning Streak, McTavish Rising, Dostal Shines

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Dec 20, 2022 90:19 Very Popular


On this episode, we discuss the Ducks back-to-back wins, Mason McTavish's stellar play, Lukas Dostal's 46-save classic performance, and much more!Support the show:Get 10% OFF tickets with promo code "CTP" at 714tickets.comSubscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Climbing The Pocket
Vikings vs Colts | The Final Score

Climbing The Pocket

Play Episode Listen Later Dec 18, 2022 77:39


Vent with us! Or not, and let's celebrate! Listen live as we go live in the final 2 minutes and ride with you through the overtime all the way to the victory. On this episode of Climbing The Pocket's “The Final Score”, we react with you! Your Minnesota Vikings had the opportunity to clinch the NFC North today. All they had to do was defeat the 4-8-1 Indianapolis Colts. The team with the worst offense in the league. After the first half of the game where the Vikings have trailed 33-0, it won't even be close to those results. Why so far have the Vikings not shown up? …And they finally did winning 39-36 in overtime. What defensive adjustments are we seeing that were promised? Not sure, but in the second half and overtime, they held the Colts to only 3 points. After the first half, the defense is well on its way to giving up over 400 yards again for the sixth game in a row. But they didn't. They held the Colts to only 341 yards in 5 quarters. Should Ed Donatell be fired? Well, somebody needs to be the scapegoat. Not this week. Our super fan, Mary Fisk, asks, “could this be the worst game in Vikings history?” I guess we have another half of football to sit through to find out. We did with the greatest comeback in NFL history. Wow! The team has at least scored in the third quarter. Can they score enough? Absolutely! They made history and won the NFC North Division crown in the process. SKOL VIKINGS! All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations and celebrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jonas, Yinka, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk, Tyler Forness @TheRealForno, and Yinka Ayinde @Saxyprince. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/hrqpGfhaBlA At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Stroke Alert
Stroke Alert December 2022

Stroke Alert

Play Episode Listen Later Dec 15, 2022 47:01


On Episode 23 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the December 2022 issue of Stroke: “Direct, Indirect, and Combined Extracranial-to-Intracranial Bypass for Adult Moyamoya Disease” and “Contemporary Incidence and Burden of Cerebral Venous Sinus Thrombosis in Children of the United States.” She also interviews Drs. Koji Tanaka and Andrew Demchuk about article “Significance of Baseline Ischemic Core Volume on Stroke Outcome After EVT in Patients Age ≥75 Years.” Dr. Negar Asdaghi:         Let's start with some questions. 1) Is direct bypass better than indirect bypass in preventing the future risk of vascular events in adult patients with moyamoya disease? 2) What is the contemporary incidence of cerebral venous sinus thrombosis in the pediatric population? 3) And finally, is endovascular therapy beneficial for patients presenting with a large ischemic core? We have the answers and much more in today's podcast. You're listening to the Stroke Alert Podcast, and this is the best in Stroke. Stay with us. Welcome back to another issue of the Stroke Alert Podcast. My name is Negar Asdaghi. I'm an Associate Professor of Neurology at the University of Miami Miller School of Medicine and your host for the monthly Stroke Alert Podcast. In our final podcast for the year, I'm thrilled to announce that Drs. Nastajjia Krementz and Eric Goldstein have joined our podcast as assistant editors to help us cover the latest and the best in the field of cerebrovascular disorder. And together, here's our article selection to close the year. As part of our Advances in Stroke, in the article titled "Focus on Anticoagulation for Valvular Heart Disease With and Without Atrial Fibrillation," we get an update on current evidence from randomized controlled trials on the use of direct oral anticoagulants or vitamin K antagonists in patients with valvular heart disease that are mechanical valves, moderate to severe mitral stenosis, or bioprosthetic valves from the perspective of stroke physicians. What that means is that data from randomized trials was analyzed based on whether the patient had a prior history of stroke or TIA. In this review, we learned that direct oral anticoagulants may be used in patients with bioprosthetic valves who have atrial fibrillation, although DOACs have never been shown to be superior over vitamin K antagonists. We also learned that vitamin K antagonists should be used in patients with rheumatic moderate to severe mitral valve stenosis or patients with mechanical valves with or without atrial fibrillation and, of course, sometimes during the first few months after either surgical or transcatheter aortic valve replacement in patients without atrial fibrillation. And finally, patients with bioprosthetic valves without AFib don't have any other indications to be treated with anticoagulants should be treated with antiplatelet monotherapy in the long run. In a separate article in this issue of the journal, from Dr. Yang and colleagues from China, we learn about the pathophysiology of radiation-induced brain injury with special attention to radiation-induced vasculopathy. These investigators show that hyperactivity of notch signaling pathway that in normal state is essential in vascular morphogenesis and maintenance of arterial identity actually results in abnormal accumulation and disturbance of vascular smooth muscle cells, resulting in arterial muscularization and arterial dysfunction seen in radiation-induced vasculopathy. What's interesting is that inhibition of the notch signaling pathway in their study resulted not only in a measurable reduction in radiation induced vasculopathy, but also an overall improvement in radiation-induced brain injury as measured by the cognitive function of the mice exposed to radiation in their study. This study takes us a step closer to possible therapeutic options for radiation-induced vasculopathy and radiation-induced brain injury using compounds that can potentially inhibit the notch signaling pathway. As always, I encourage you to review these articles in detail in addition to listening to our podcast. For our interview today, I have a special guest who's not only a prominent researcher and a pioneer in the field of acute stroke therapies, but also, he's an experienced educator who has trained many of the current leaders in the field of vascular neurology and has been influential in shaping the careers of many vascular neurology fellows over the years. Take a listen. Dr. Andrew Demchuk:   I've had the privilege of training fellows. I've been the director since 2004, and we've trained close to 100 fellows in Calgary over 20-some years now. Really, it's frankly an honor and privilege to be able to do that. These individuals come from all over the world. They're here to dedicate themselves to learning a subspecialty really, really well, and it's just a fantastic experience to interact with them all and all their cultures to help them learn those things, and doing it in a fun, enjoyable, comprehensive way. Dr. Negar Asdaghi:         And those are the words of Dr. Andrew Demchuk, who's incidentally my own vascular fellowship director as well. Andrew joins me all the way from Canada to talk about his latest paper on the very hot topic of outcomes of endovascular therapy in patients presenting with a large ischemic core. And true to form, he's accompanied by one of his current vascular fellows. The interview is definitely worth the wait after we review these two articles. Most of us have heard of the term "moyamoya." First described in Japan in 1950s, the term refers to occlusion or stenosis of the terminal portion of the internal carotid artery and is associated with dilated collateral vessels of the proximal middle cerebral artery. These collaterals have a hazy appearance on angiography resembling the puff of smoke, which is Japanese for "moyamoya." Moyamoya is categorized into two broad categories of moyamoya syndrome and moyamoya disease. Syndrome refers to the situations where the occlusion occurs due to another condition. Conditions such as Down syndrome, sickle cell disease, neurofibromatosis type one have all been recognized as associated with moyamoya syndrome. Of course, moyamoya syndrome can occur due to a secondary insult to the blood vessels, anything from radiation vasculopathy, as we reviewed earlier in the podcast, to autoimmune vasculitis, or even good old advanced intracranial atherosclerosis involving the distal ICA region can cause moyamoya syndrome. Now, in contrast to moyamoya syndrome, the term "moyamoya disease" is reserved for individuals with no vascular risk factors or known moyamoya predisposing conditions other than, of course, some potential genetic factors. The most recognized genetic association for moyamoya disease is polymorphism in the ring finger protein 213, or RNF213, gene on chromosome 17. But we also have to keep in mind that the majority of moyamoya disease patients have no identified genetic abnormalities. So, moyamoya is truly a complex condition, and the physicians have to navigate the many possible etiologies that may cause or be associated with this condition. But when it comes to treatment options, we're really limited here. Antiplatelets are generally used and have been shown to reduce mortality in both moyamoya disease and syndrome, and especially cilostazol, which is the favorite antiplatelet therapy of our own assistant editor, Eric, has been shown to be significantly associated with increased survival rate in patients with moyamoya disease. Eric really wanted me to talk about a recently published study out of Korea, which included over 9,000 patients, and that showed that patients treated with cilostazol had a better survival rate than any other antiplatelet therapies. Apart from antiplatelet therapies, medical treatment includes optimizing all other vascular risk factors, which, as we mentioned, are rarely present in this population. So, it all comes down to most cases, at some point, needing surgical treatment, with bypass surgery being the most commonly surgical intervention for this population. Three flavors of bypass are used: indirect, direct, or combination of the two. Indirect bypasses are kind of like long-term investments where the surgeon moves vascular tissue to the surface of the brain in hopes of promoting angiogenesis. Several procedures, such as performing multiple burr holes, pial synangiosis, dural inversion, or omental transposition, among other methods, are used. And broadly speaking, we can think of indirect procedures as angiogenesis-dependent methods, the effect of which takes months to recognize and, in general, are thought to be more efficacious in the pediatric population than the adult population. The direct bypass, in contrast, commonly referred to as extracranial-to-intracranial, or ECIC, bypass, is more of an immediate reward where the surgeon stitches a vessel directly from a donor extracranial branch, typically the superficial temporal artery, to a recipient artery, typically the middle cerebral artery, to provide a direct anastomosis between the two vessels. There are technical variations, of course, especially with regards to the number of donors and recipient arteries used, but essentially this method is an angiogenesis-independent method that results in a quicker revascularization, but it's unclear if this strategy is long lasting. A combination of direct and indirect bypass can also be used. So, the question is, which method is better, especially in the adult population? In this issue of the journal, in the study titled "Direct, Indirect, and Combined ECIC Bypass for Adult Moyamoya Disease," Dr. Nickalus Khan and colleagues report on a meta-analysis and systematic review of those with adult moyamoya disease who underwent either direct, indirect, or a combination bypass. The main study question was whether there's a difference in the rates of early ischemic or hemorrhagic strokes, defined as strokes occurring within 30 days of bypass, or late strokes, defined as strokes occurring after 30 days of bypass, in this population when comparing the different surgical techniques. They also compared the "favorable" outcome rate; however, this outcome was defined in each study between the various broad techniques of direct, indirect, and combined bypass. So, with that, let's take a very quick look at their methodology. They screened more than 4,000 articles and identified 143 articles for their pooled analysis, the majority of articles being from Eastern Asian-based regions, and they had close to 4,000 combined, 4,000 direct, and 4,000 indirect bypass procedures for this analysis. And they had an average follow-up of over three and a half years. So, this is a great sample size for this large, pooled analysis. But they also performed a smaller meta-analysis where they were much more stringent with article selection, excluding pediatric papers, excluding articles containing only one surgical modality, or articles with insufficient outcome data. So, for that meta-analysis, they only had 43 articles qualified and were included in that meta-analysis. So, what did they find? In the larger pooled analysis, a significant benefit in favor of both direct and combined bypass techniques were noted in reduction of early and late ischemic strokes and late intracerebral hemorrhage. Also, a higher rate of that sort of vague favorable outcome was noted with both the direct or combined methods as compared to when indirect bypass techniques were used alone. So, everything in the large, pooled analysis pointed towards the direct bypass or combined technique performing better than all indirect bypass techniques, with only one exception, which was a lower incidence of early intracerebral hemorrhage rate in indirect bypass cases. So, that's one point to keep in mind. The second point was when they compared combined techniques to direct bypass. Overall, these procedures had more or less the same outcomes with the exception that the rate of late ischemic stroke was lower in the combined group than the direct bypass group. So, this is sort of the overall summary of what they found in that large, pooled analysis. When they were much more stringent with their selection criteria, focusing on the smaller meta-analysis portion of the study, what they found was that in the short term, there were no differences in outcomes of any type of stroke between any of these methods. So, basically, people, regardless of the type of bypasses they received, did the same with regards to the risk of intracerebral hemorrhage and ischemic stroke recurrence within the first 30 days after the bypass. But for the late stroke outcomes, whether ischemic or hemorrhagic, those with indirect bypass were nearly twofold more likely to develop late stroke after 30 days compared to those who've undergone the direct bypass. A similar pattern was found comparing combined bypass versus indirect bypass, in general, beyond the 30 days, with combined bypass doing better. Comparing direct versus combined bypass showed no difference regardless of timeframe. So, in summary, overall, it appears that combined or direct bypasses may be the best surgical strategies for treatment of adult patients with moyamoya disease. This study, of course, has many limitations, as does any meta-analysis, but most importantly, the authors focused on moyamoya disease in their analysis. It is presumed, but really unclear if patients with moyamoya syndrome would respond similarly to these different techniques. So, the question is, what surgical procedure are you using at your institution for treatment of adult moyamoya disease patients? And, of course, Eric wanted me to ask if your antiplatelet of choice is cilostazol for this population, yes or no. Leave us your comments, and let us know. Venous sinus thrombosis, or CVST, is a less common form of stroke most commonly affecting women and young individuals. In our past podcast, we've covered many aspects of CVST, especially when it comes to therapy with anticoagulation, anticoagulant of choice, and duration of therapy. In the October podcast, we reviewed a systematic review and meta-analysis comparing direct oral anticoagulants to vitamin K antagonists in the adult patients with CVST. But there are many aspects of this disease that we have not yet covered. For instance, you may ask, how common is this relatively uncommon condition? In the adult population, the incidence of CVST varies depending on the age of individuals studied, and ranges between 1.3 to 2.7 per 100,000 in women between the ages of 31 to 50, which is the adult population at highest risk for this disease. But the incidence of CVST, for instance, in the pediatric population is largely unknown. Some studies suggested an incidence rate of 0.67 per 100,000 in the pediatric population. That's roughly less than half the incidence rate in young female adults, but these reports are from the 1990s and are likely very outdated. Nowadays, many of the pediatric conditions, especially infectious conditions, that can predispose children to CVST are more readily diagnosed and treated. On the other hand, we now perform a lot more imaging than 30 years ago. Our neuroimaging modalities are more accurate, so we are more likely to diagnose CVST than before. So, the question is, what is the contemporary incidence of pediatric cerebral venous sinus thrombosis? In this issue of the journal, in the study titled "Contemporary Incidence and Burden of Cerebral Venous Sinus Thrombosis in Children of the United States," Dr. Fadar Otite and colleagues conducted a retrospective analysis of the New York State Inpatient Database, or SID, from 2006 to 2018, and the National Kids Inpatient Database, referred to as KID, from 2006 to 2019, for all hospitalized CVST cases. KID is the largest publicly-available pediatric inpatient care database in the United States, containing about 3 million pediatric discharges. They included over 700 hospitalized CVST cases from the SID database and 6,100 hospitalizations from the national KID database for the current analysis. And here's what they found. Number one, in terms of significant risk factors associated with CVST, congenital circulatory system anomalies, infections, head trauma, dehydration, and anemia were amongst the top CVST risk factors in the pediatric population. So that's very good to know. Number two, in terms of presentation, seizures were the most common presentation among all pediatric age groups, with close to half of infants with CVST presenting with seizures. Number three, in terms of outcomes, the rate of mortality was twice higher in the infants group as compared to all other age groups. And finally, the overall incidence of CVST, which was the main question of the paper, in this population was 1.1 per 100,000 per year, with a peak incidence during infancy of 6.4 per 100,000 per year. Interestingly, incident admissions also increased annually by 3.8% throughout the study period, which was close to 15 years in this paper. And the national burden of hospitalization dramatically and exponentially grew during the study period. So, here are the top three points from this study. Point one: Girls included less than half of all admissions nationally and statewide, and the overall burden of CVST was higher in boys than girls. That's a dramatic difference between the pediatric and adult populations. Point two: Incidence of CVST in infants was higher than five times that of other age groups at 6.4 per 100,000 compared to overall incidence in children, which was 1.1 per 100,000 people per year. Mortality was also two times higher in infants than in any other age group. And finally, point 3, incident admissions and national burden of hospitalization have dramatically increased over time, but it remains unclear whether true incidence has been on the rise or if simply more cases are recognized nowadays due to heightened awareness of this condition and our advanced neuroimaging capabilities. This study, of course, has some limitations. Data was only obtained on patients admitted, so many patients that may have had CVST but not admitted are not captured in this database. So, in summary, CVST can have catastrophic consequences in children and lead to long-term neurological deficits. Having a high clinical suspicion and early recognition remain crucial for prompt treatment and improved outcomes in this population. Dr. Negar Asdaghi:         Endovascular treatment, or EVT, is an effective method to achieve recanalization and to improve clinical outcomes in ischemic stroke patients with a target vessel occlusion. Both advanced age and having a large infarct volume at the time of presentation are negative predictors of beneficial outcomes post-EVT. Despite this, the neurological benefits of EVT seem to persist across the spectrum of age, and the same has been observed for a range of ischemic core volumes. But it's important to note that, in general, patients presenting with large ischemic core volumes were excluded from the original thrombectomy studies, and currently there's several ongoing trials to determine whether EVT is beneficial for the large core population. Now, the question that everyone is interested in answering is whether there is an actual ischemic core volume beyond which endovascular therapy is either futile or potentially even harmful, and if this magic futile core volume is the same for all patients, or does it differ depending on the age and other factors. In a previous podcast, in an interview with Dr. Osama Zaidat, we learned about that important interaction between the presenting ischemic core volume as measured by ASPECTS score and advanced age in an analysis of patients enrolled in the STRATIS registry. In that study, no one over the age of 75 achieved functional independence post-EVT if the presenting ASPECTS score was under 5 regardless of the angiographic outcomes. In that interview, we also discussed the limitations of STRATIS registry as a non-randomized, single-arm study, and the issues surrounding using ASPECTS score to define ischemic core. In today's podcast, we're going to revisit the important interaction between the presenting ischemic core volume and age while reviewing a pooled analysis of seven endovascular clinical trials in the paper titled "Significance of Baseline Ischemic Core Volume on Stroke Outcome After Endovascular Therapy in Patients Age 75 Years or Older." I'm delighted to be joined today by the first and senior authors of this paper, Drs. Koji Tanaka and Andrew Demchuk. Dr. Tanaka is an Assistant Professor of Neurology at Kyushu University in Japan. With his experience working at the leading center for conducting stroke clinical trials in Osaka, he has now joined the Calgary Stroke Program as a research fellow. And he's accompanied today by his fellowship director, Dr. Demchuk. Dr. Demchuk, of course, needs no introduction to our Stroke readership and our podcast audience. He's a Professor of Neurology at the University of Calgary Cumming School of Medicine. He's a stroke neurologist and a leader in the field of cerebrovascular research who has been involved in multiple clinical studies and randomized trials, including the seminal studies that led to the approval of EVT as the standard of care for treatment of stroke. And, of course, he's a very special guest of this podcast this morning as he was my very own fellowship director. Top of the morning to you both, Andrew and Koji. Welcome to the podcast. Dr. Andrew Demchuk:   Thanks, Negar. It's great to be here. Dr. Koji Tanaka:               Thank you very much for your invitation. That is a great honor to be here. Dr. Negar Asdaghi:         Thank you both. Andrew, let's start with you. Can you please provide us some background on the pooled analysis and the HERMES collaboration, please? Dr. Andrew Demchuk:   Yeah, HERMES is a really, it's been a really fun journey. Years back, when these trials all came out roughly at the same time, right? There was a real quick succession of trials, the MR CLEAN trial was obviously first, and ESCAPE and others quickly followed it. It became very clear to us that it just made total sense to collaborate. And so we got together as a group and decided we will pool the data. We'll do it in a very careful scientific way with basically an independent statistical analysis, and develop a core imaging lab, and really actually share the workload amongst us. I remember one of the really interesting tidbits about HERMES is when we got together, in order, I think, to really build trust in the group, one of the important things we decided early was we were going to have a snake draft. If you don't know what a snake draft is, Negar, it's essentially where you take turns selecting a topic through each of the trials. So, every trialist got an opportunity to pick a topic, and we just went down the list until everyone had their turn, and then we'd start over again and do it again. And I think that really worked very well to be as democratic as possible with this, and as fair. And it really allowed for a lot to get done because whoever was motivated in the collaboration was able to do an analysis. Dr. Negar Asdaghi:         So, what a great summary of this collaboration. So, it's true collaboration between the trialists that basically gave us those seven original randomized trials. Andrew, can I just stay with you, and can you tell us a little bit about the patient population that were enrolled in those trials? Dr. Andrew Demchuk:   Yeah, I think one of the important things to know, and I think a limitation for any kind of analysis like this, is the trials generally were small core trials, right? I mean there are some, MR CLEAN was certainly a more generalized population, but many other trials, including ESCAPE, I mean the "S" and the "C" in ESCAPE is "small core," right? And so a lot of these trials were small core. So, we don't have a lot of data in larger core patients. But, as you can imagine when you do core lab analysis, you realize that some of the stroke patients weren't as small core as we thought they were when we enrolled them. So, there is some sufficient data to hypothesize. I would consider this paper very much hypothesis-generating. So, yeah, it is a limitation to be considered here. I mean, our sample size isn't very large in the big core patients. Dr. Negar Asdaghi:         Perfect. Thank you, Andrew. So, again, a recap for our listeners, that we are looking at pooled analysis of seven original trials of thrombectomy, but keeping in mind that those patients that were enrolled in the trials had, generally speaking, small presenting ischemic core. So, now, Koji, on to you. Can you walk us please through the current study, and what was the premise of it, and who was actually included in this study? Dr. Koji Tanaka:               Yes. In this study, we aimed to evaluate association between baseline ischemic core volume and the benefit of endovascular therapy over the best medical treatment on functional outcomes. Patients were categorized age over 75 years, and less than 75 years old. The primary outcome of interest was a modified Rankin Scale of three or less, and we included 899 patients who underwent this baseline ischemic core volume measurement, which corresponds to 51% of our patients in the HERMES collaboration dataset. Dr. Negar Asdaghi:         All right. So, just a quick recap of what you said. Thank you for this. So, we have 899 patients. Those patients were all included in the HERMES collaboration, but, of course, these are patients in whom we had presenting ischemic core measurements. And that will get me, actually, Koji, to my second question. Can you please walk us through how you did analysis of ischemic core volume measurements in this study? Dr. Koji Tanaka:               In this study, ischemic core volume was measured by CT perfusion in 591 patients and by diffusion-weighted imaging in 309 patients. We defined the ischemic core volume as a relative cerebral blood flow of less than 30% in CT perfusion and diffusion coefficient of less than 620 square micrometers per second in diffusion-weighted imaging. Previous studies showed ASPECTS moderately correlate with ischemic core volume in both CT perfusion and diffusion-weighted imaging. For example, ASPECTS of eight can be considered as ischemic core volume of 20 milliliters. But underlying [inaudible 00:28:21] were different between CT perfusion and diffusion-weighted imaging, and previous studies suggested CT perfusion occasionally overestimates the ischemic core volume was on diffusion-weighted imaging. In this study, the results did not change when analyzing CT perfusion and diffusion-weighted imaging separately. Dr. Andrew Demchuk:   Yeah, that's a really important point Koji makes, is that because we had sort of a, not quite a 50/50 split, we had a 60/40 split of CTP and DWI, we did analyze them separately, and the odds ratios of treatment effect were pretty similar at different core thresholds. So, they're fairly similar when you separate them out, but obviously the methodology is a little different between a CTP and a diffusion. And to Koji's point, he's absolutely right, the CTP has a tendency to slightly overestimate core when you compare to diffusion. Dr. Negar Asdaghi:         Yeah, and thank you. I think you already sort of alluded to what I was going to ask you and Koji, because, in reality, we have different ways of measuring core. We have the ASPECTS score, which is just a quick and dirty way of estimating or guesstimating core, and then we have CT perfusion, and we also have diffusion that sometimes is available to us, but not always. And the question is, in the heat of it, how we're going to measure the volume. With post-processing softwares, with CT perfusion, we get a quick potential ischemic core volume, but we don't have that capability with diffusion even if we did get diffusion. So, I think it's important to know that what Koji mentioned, an ASPECTS of eight can, more or less, in a quick fashion, be thought of as about 20 cc of core. And the other point that Koji raised was that CTP, again, this is sort of ballpark, can tend to overestimate ischemic core if you were to compare that with diffusion-weighted data. So, with that, now we have a study in which we have core volumes, and we're going to look at outcomes from endovascular thrombectomies compared to best medical management and see whether there is a correlation or interaction between ischemic core presentation, especially age. So, my next question would be to Andrew, can you walk us please through the main findings of the paper? Dr. Andrew Demchuk:   The whole goal of this paper was really to understand, are there thresholds in the older patients? When we looked at overall, and Bruce Campbell and the team wrote an important paper with HERMES and the CTP cohort overall, and the sort of message there was if you looked at shift analysis, there wasn't actually a core threshold found at all in HERMES for lack of benefit. There was a benefit across all the core volumes, but, of course, that's all ages. So, we were really interested in looking at the older patients because we felt there's more likelihood the core volume will matter in the elderly than in the younger patient. We know the younger population, it benefits overwhelmingly with EVT, it's hard to even find a core volume threshold. So, that was a premise. Essentially, we had 247 patients over 75 in the overall cohort, of which 98 had EVT. So, it was a decent population, and not a huge sample, but a decent sample. And so we looked at various things. The first thing that was interesting we found was that infarct volumes, the average infarct volume to achieve an mRS three or less, was lower in the older patients, significantly lower, was 23.9 for younger patients under 75 and 10.7 for the older patients. You tend to have much smaller infarcts to achieve good outcome. And so that was kind of interesting, and I think that's been shown by others. Then we got into the weeds to try to figure out, OK, what are these thresholds? And if there's one figure that matters, Negar, you know me to always point out that there's always one figure or table in a paper that's kind of where the money is, where the real learning is, and that's Figure 2 on this paper in my opinion, beautiful figure with four figure A, B, C, and D. And it really sort of nicely highlights these issues and these cutoffs. But what we saw is that in the older patients who received EVT, around 50 mils seemed to be a threshold to achieve zero three, you had to, to see treatment effect, you had to have a baseline infarct volume less than 50 mils for a zero three outcome advantage. For zero four, it was 85 mils. And then we looked at this issue of what we called futility, true futility. And that's a very controversial thing. What is futility, or how do you measure futility? And really, I think, we even had a debate about this as a HERMES group when we were designing the analysis, and we sort of landed on mRS five six. A 90% chance of mRS five six, right? That's quite the bar, right, to say true futility because some people argue mRS four is still not a horrible outcome. Culturally, that is an OK outcome in some situations. But when we did use that five six 90% threshold, it was 132 mils. So, you're getting up to these really large volumes. But here's the catcher in the whole thing, and Koji will probably speak to this a bit more. I don't want to steal his thunder too much, but this issue of reperfusion seemed to matter in this. And we'll come back to that maybe with another question. Reperfusion matters a lot when you think about these thresholds. Dr. Negar Asdaghi:         OK, so, Andrew, a lot of information, I don't know if I need a recap myself to recap, but basically what you mentioned is that for the older patients who received EVT, if we keep our eyes on the outcome of mRS of zero to three, it seems to be the magic core volume for that outcome post-endovascular therapy that it lands on the magic volume of 50 cc core. Did I get that right? Dr. Andrew Demchuk:   That's correct. Dr. Negar Asdaghi:         Then if you're still a bit more lenient with the definitions of what is favorable outcome, what outcomes we're looking at and so on, so forth, for an mRS of five to six, then when we talk about futility of endovascular thrombectomy, the volume that you mentioned, and again I want to ask you this, this volume is for elderly over the age of 75, is 130 mil. Dr. Andrew Demchuk:   132, but yeah, absolutely. But there's a real catcher here, and we need to really emphasize the catcher in this. Dr. Negar Asdaghi:         Okay. I will ask you one more question before I go to Koji, which I'm sure is going to tell us more about that catcher. Andrew, can you please tell us about the factor of time? I feel like that is something that we need to discuss, as well. Your study included patients early on in their stroke onset, but we're talking about an important interaction. The question is, do you think the results of this interaction would be different or impacted by the value of time? Dr. Andrew Demchuk:   Hypothetically? It must, right? I think that that must be the case. We don't have any data specific to this. That would be an interesting Aurora analysis to do. Now, of course, the challenge with late window analysis is, we are really small core in our late window trials, we probably have even a much smaller proportion of large cores. So, to be able to even tackle that question in the late window is, I don't know if we have the data yet, to be honest. But it makes sense that you would expect the thresholds to be a bit lower the later you are in the window. But that is a hypothetical opinion. Dr. Negar Asdaghi:         Right, so, I want to take that and come to Koji. I want to digress a little bit to Koji and see how we can understand the finding of this current analysis of this paper. So, small core patients early on into their onset, we're looking at the interaction between age and their core volume and coming up with numbers 50 cc for the elderly population. If you're looking at the outcome of zero to three or 132, as Andrew pointed out, for an MRS of much higher, four or five. Dr. Andrew Demchuk:   Actually five, six, 90% chance of five, six. So, it's there. It's like almost everybody got five, six, took 132 mils to get there. So, it's like this extreme outcome. Dr. Negar Asdaghi:         Right, so, exactly, and I have to correct it, again, mRS of five or six or dead or almost dead mRS basically. Dr. Andrew Demchuk:   In 90% of patients. Dr. Negar Asdaghi:         90% of patients. So, we have these important numbers here, and I want us to basically understand these numbers in these volumes in the context of the recently published RESCUE-Japan LIMIT study. Can you tell us a little bit about that study and how we can make sense of these volumes in the setting of that paper? Dr. Koji Tanaka:               In the recent RESCUE-Japan LIMIT trial, the median ASPECTS was lower, and baseline ischemic core volume was greater than those in our study. And surprisingly, the median ischemic core volume in that trial was close to our threshold to predict less than 10% of patients achieve a modified Rankin Scale of four or less after endovascular therapy. We thought this is due to much higher complete reperfusion rate in HERMES patient. We have much interest in their additional analysis for outcomes in elderly patients by reperfusion status. This potential benefit of endovascular therapy in the area is promising for the future clinical trials. Dr. Andrew Demchuk:   I think just to add to that, it was actually really interesting, Negar, because when we were analyzing all of this and then the trial came up and it was actually really nice because we're like, OK, how does our data relate to their data? And that's where Table 2 comes in, and it would almost be worth putting on the pod, whatever, I don't know if you have on your podcast website, you have one figure that you can sit there with as you listen to the podcast, because that would be the figure. Dr. Negar Asdaghi:         We'll work on that Andrew, but tell us a little bit more because, really, when I read the trial results, the way I understand it is that people enrolled in RESCUE-Japan that were older than 75, and these are all large core patients, benefited more from endovascular therapy than their younger counterpart. How do I understand that? I don't know how to wrap my head around that finding. Dr. Andrew Demchuk:   You want to try to answer that, and then I'll add? Dr. Koji Tanaka:               As I mentioned previously, we want to know about the exact patient population just only for elderly patients, whether they have a exactly larger ischemic core volume or as well as their functional outcome. How many patients achieved modified Rankin Scale four or less or three or less, or more than five or six? Dr. Andrew Demchuk:   Koji's point's very important. We actually don't have the breakdown of the mRS, so we don't know if they created a lot of fours, or threes, or what. So, that's one issue. But I think that the key to this whole thing is to understand that this is a 2022 trial. HERMES data is essentially a 2015 equivalent where we're looking at a number of clinical trials who roughly ended between 2014, 2016. So, the technology, the technique, the operators, are just at a different level back then than now. And quite frankly, EVT is an improving treatment. We probably don't even fully understand how much, I mean, we're just getting better at it. And I think what's happened here is the reperfusion rates have improved. And our HERMES reperfusion rates, remind me, Koji, I think they're about half, we think, in HERMES, than like the TICI 2bs, threes, are half in HERMES what they got in RESCUE-Japan LIMIT. So, when you achieve successful reperfusion, what were the numbers here? TICI 3 was 43% in the Japan RESCUE LIMIT, and 8.6% in HERMES. Okay, TICI 3s were not ... Now that may be slight differences in core lab interpretation, but we were just starting to get good at 3s. We were getting a lot of 2bs and some 2cs, but we weren't getting a massive number of 3s back in 2015. Well, voilà, now we are, right? We're hitting home runs when we didn't before. And I think that has really shifted the goalposts on the large core. If you open the vessel, they can still do well if they're elderly, but you've got to really open that vessel. And in HERMES, we only did that in a small portion of patients. So, these thresholds are sort of representative of 2015 skill. Dr. Negar Asdaghi:         Golden points, Andrew and Koji, both of you. I want to recap what you mentioned here. A note to all of our audience and listeners that we are looking at an analysis with RESCUE-Japan, an analysis of a 2022 study. And the patient population that were enrolled were also treated much later in terms of time than the patient population that was enrolled in the HERMES collaboration and in all of the trials that contributed to HERMES. So, we've got to remember that EVT is this fluid, ongoing, everyday-improving therapy, from our techniques to everything else, you know, how fast we get patients to the angiosuite. And the point that you raise, I want to repeat that, the percentage or the odds of achieving a perfect reperfusion was, in RESCUE-Japan, was 43% odds of TICI 3 reperfusion, whereas only 8.6%. So, when we're talking about all of these predictive modeling or predictive factors that will tell us who's going to do well, who's not going to do well, it also is predicated on the angiographic success. And perhaps in the earlier trials or even the early study that we covered as part of the STRATIS registry, we put everybody, TICI 3s with TICI 2b or better, whereas nowadays we accept the best, TICI 3s, and maybe that improved percentage in the most recent trial, the RESCUE-Japan, really did what it had to be done for the elderly population to keep that in mind. And Andrew, before we end our interview, I want us to get your top two takeaway messages from this paper. Dr. Andrew Demchuk:   Clearly, elderly patients do better when their strokes are smaller, that we know, compared to younger patients. But it's all about hitting the home run. It's all about hitting the home run. Figure 2C and 2D, you can see that if you achieve that high TICI score, a significant proportion of elderly patients potentially could still benefit, 30–40% reasonable outcomes with bigger cores if you get those high TICI scores. So, it is about hitting the home run in reperfusion in the elderly. You need to go for it, and hopefully you're successful, because if reperfusion isn't successful, then generally the outcomes are not ideal and they certainly worsen as the core volumes become larger, bigger. Dr. Negar Asdaghi:         Before I ended the interview, given Andrew's tremendous experience as a longtime fellowship director and seeing that he was flanked by two of his fellows, one past, myself, and one present, Koji, I had to ask him one final question of what his philosophy is as an educator. Dr. Andrew Demchuk:   I have a sort of philosophy on life with fellows. I always look for the special power in a fellow. I realized a long time ago we're all, we're not perfect, nobody's perfect, I'm not perfect, but there's usually a special power in people, and if you spend the time to get to know them, you identify that special power, and you really help harness it because you know that if they can harness it when they go back to their faculty job, they're going to really contribute something special to their team, right? You can imagine six special powers from six different people in a team. Now you've got a real team, right? If you know what your power is, you know your limitations, but you know where your strengths you can add to the group, and that's what we try to do here when we can. It's not always, you know, special powers, you have to kind of seek them out. But they're there in most people, and that's really important for career down the line. Dr. Negar Asdaghi:         And this concludes our podcast for the December 2022 issue of Stroke. Please be sure to check out this month's table of contents for the full list of publications, including our very interesting Stroke Images series. In this month, we have a case of progressive cervical myelopathy secondary to a dural AV fistula supplied by the anterior inferior cerebellar artery. We also have a separate case of carotid rete mirabile imaged with a four-dimensional flow MRI study. And with these cases, we bring our 2022 Stroke Alert Podcast series to an end. Over the past 12 months, we've ended our podcasts with various inspirational tales. From the moving account of the American runner Steve Prefontaine and the remarkable journey of the Syrian refugee and Olympian swimmer Yusra Mardini, to the discovery of positron and Commander Armstrong's landing on the moon, our podcast stories have but one thing in common, which is the story of human perseverance and consistency in the face of hardship. So, as we end 2022 to start 2023 anew, Andrew's comments on finding that special power in each of us resonate with our resolution to stay alert with Stroke Alert. This program is copyright of the American Heart Association, 2022. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, visit AHAjournals.org.

Anaheim Calling: for Anaheim Ducks fans
Ducks Trade Chips, Coaching Changes, Zegras/Terry Contracts

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Dec 15, 2022 79:36


On this episode, we answer listener questions regarding who the Ducks may trade this season, if a change is coming behind the bench, Zegras and Terry's future contracts, and many more questions and topics. Enjoy! Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpodSubscribe to our live Twitch stream twitch.tv/crashthepondBecome a Patreon patron: patreon.com/crashthepondCheck out the video version of the podcast: youtube.com/crashthepondOr leave us a review on Apple PodcastsThanks for listening!

DH Unplugged
DHUnplugged #633: 2022 Exit Plan

DH Unplugged

Play Episode Listen Later Dec 14, 2022 62:20


Make up your mind - China unhappy about everything. Yellen says inflation to cool. CPI comes in a bit better than feared. What is in store for the end of 2022 and into 2023? Announcing the 2022 Closest to The Pin Cup! PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter Warm Up - Announcing Winner of latest CTP AND Entries for the CTP Cup 2022 - China lockdowns - scaring citizens - End of the year - Goodbye 2022 - People still concerned about 2023 - Musk boo'd ay Dave Chapelle stand-up - China - from zero-Covid to 100% Covid - Markets convulsing.... - Sam Bankman Fried Jailed - or just Sam Bankman NotFree or Sam Bankman Jailed Market Update -The S&P 500 index fell 3.4% last week as investors worried that a recent round of better-than-expected economic data might prompt the Federal Reserve to keep its key rate higher for longer. - All of the S&P 500's sectors fell last week. -- Energy had the largest percentage drop, down 8.4%, followed by communication services, which slid 5.4%, and consumer discretionary, which fell 4.5%. Other decliners included financials, down 3.9%; and technology and materials, which slipped 3.3% each. The smallest decline came from utilities, which edged down 0.3%. - All eyes are the Fed meeting this week - FOMC rate decision on Thursday (75% prob of a 50 basis point hike) - CPI Report released today!!!!!!!!!!!!!!!!!!!!!!! Amazing turn of events... 2022 Exit Plan - Investors have good deal of capital losses - End of year could see some selling to book those deductions - - If that happens, look for a big January Effect mid January 2023 - Investors seem mentally exhausted from 2022 - get biz done now until end of year and "hope" for a more pleasant 2023 - 2023 may be  just as volatile as Fed not done CPI Report - Lighter than feared - markets go bananas on the print (November Core CPI 0.2% vs. 0.3% Briefing.com consensus; prior 0.3%) -  Total CPI was up "only" 7.1%, versus 7.7% in October, and core-CPI was up "only" 6.0%, versus 6.3% in October. - 10 year moves to 3.44%, USD drops hard, Stock futures soar - CME Fed Funds Futures at 79% for a 50 bps hike; One month ago it was at 80.6% (Meeting on Dec 14) CPI REPORT REACTION CPI Report Reaction One Musk - Got on stage at Dave Chapelle stand up concert - - Introduced as the world's richest person (which he no longer  is - Bernie Arnault took over - LVMH) - Supposedly significant # of people booing - (San Francisco venue) - Video of event ripped down off of Twitter (This is the problem - what happened to free speech?) CTP for 2022 - Past Winners Only for the CUP Marcus Galliford David Norman Paul Retzlaff Simon Lutzenberger Michael Devietro Matheau Phillips Rusty Shacklefordd DJIA is the index you will be guessing - you have until 12/21/2022 to enter. - Emails went out to all of you - NO ONE ELSE ENTER - Your price guess will be deleted if you are not the someone mentioned above. Not Pretty Fixed (Broken) Income Returns $600 = 1099K - Venmo, Paypal over $600 will be reported to IRS - Supposed to be for business transactions --- IRS admits, some personal transactions may be coded incorrectly - - BUT, all income is required to be reported, so this impacts you if you have not been compliant - - - ODD - Zelle is not reporting any transactions to the IRS.... -- - - - Zelle itself said it does not have to declare transactions made through the payment service because it is a network that does not hold the funds 2023 - Collection Social Security? - "Your Social Security benefits will increase by 8.7% in 2023 because of a rise in cost of living," the Social Security Administration states in the annual statem...

Climbing The Pocket
Vikings vs Lions | The Final Score

Climbing The Pocket

Play Episode Listen Later Dec 12, 2022 68:07


On this episode of Climbing The Pocket's “The Final Score”, we react with you! The Minnesota Vikings have traveled to Detroit to play the Lions. They have a chance to win the NFC North division with a win over the Detroit Lions. Will they do that? Nope, they lost 34-23. If the first half is any indication, we are likely to be disappointed. Can they pull off a comeback in the second half? Negative, the did not even though the tried. They have done it numerous times this season so far, and could this be another one? No. All the inner division games are tough and can be weird. Why should this one be different? Right? Right! Why does this team make it so hard on Vikings fans? The are still 10-3 and assured of winning the division. Just not today. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jonas, Jayson, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/k4V1luEZQu4 At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Chasing That Paper!
NFL Patriots vs Cardinals Betting Preview, NBA,CBB & NHL with Iain MacMillan | Monday, December 12th

Chasing That Paper!

Play Episode Listen Later Dec 12, 2022 47:39


On today's "Chasing That Paper!" Joe Osborne & Iain MacMillan dove into the latest odds, best bets, props and trends across the daily sports landscape! TOPICS: • Welcome to "Chasing That Paper!" (00:00)• Joe & Iain gives out their Monday Night NFL picks along with picks for NBA, CBB & NHL (02:11)• Joe & Iain recap the NFL Week and Joe goes on an rant about the Miami Dolphins loss to the Chargers (14:12) • Super Bowl Odds Breakdown (28:13)• CTP crew Picks & UFC 282 Thoughts (36:15)Make sure check out the VegasInsider YouTube Channel for more gambling content!

Bare in B-Lo
26: How To Navigate the World of Mental Health, ft. Allie Cataldi NCC, LCMHCA, CTP

Bare in B-Lo

Play Episode Listen Later Dec 11, 2022 42:46


The gals couldn't be more excited to host therapist Allie Cataldi today, also known as Cassie's cousin! It was a pleasure talking with her, and learning all about the ins and outs of the mental health system.  So, get your pens and notepads out baddies, today we learn the difference between the types of mental health professionals, how to navigate your first therapy visit, and financial options for treatment. Allie gives great tips for anyone looking for help. Please enjoy this very eye opening and informative episode today! And the gals think it's safe to say Allie will 100% be back!! B-LO SHOUT OUT THIS WEEK: For Retail Therapy - Buffalo Holiday Market @buffalo.holiday.market To Give Back - Totally Buffalo Cares @totallybuffalocares & Step Out Buffalo @stepoutbuffalo Allie Cataldi, NCC, LCMHCA, CTP @mindful.emotional.connection

Climbing The Pocket
Vikings vs Jets | The Final Score

Climbing The Pocket

Play Episode Listen Later Dec 4, 2022 54:24


On this episode of Climbing The Pocket's “The Final Score”, we react with you! Vikings win! Vikings win in! The vaunted defense of the New York Jets has come to town. Can the Minnesota Vikings keep winning ways on track? Somehow, someway, they did. Will Kirk Cousins be hot to throw a lot of receptions? No. He had a bad day, but he did make some clutch throws when it was absolutely necessary. Can the defense stop Mike White and the Jets' offense? When they had too at the end of the game. It was another cardiologist special down to the last 10 seconds. Will Sauce Gardner travel with Justin Jefferson from side to side? He did not. Can Kevin O'Connell increase his win total against a team that cut him years ago? Yes he can. The Vikings are now 10-2 baby! The Vikings took an early lead, but are looking to give it all back. Why do they do this? We still want to know. Do they want another chance at a comeback? No, but they did let it become way too close for comfort. The fans wanted them to put away the Jets, but have failed to do so. At least the Ed Donatell defense has held the Jets to 5 field goals so far. That was short lived, but they came through in the end with a Camryn Bynum interception on 4th and goal. Ugh… Let's go Vikings! All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and share your frustrations. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Tyler, Flip, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Talking with the Experts
2022 EP #401 Jim Downes - Future-Focused Accounting Your Company's Profitability Gamechanger

Talking with the Experts

Play Episode Listen Later Dec 2, 2022 30:23


In this episode of Talking with the Experts, learn how to use your business numbers to develop a long-term strategic game plan and increase profitability. Jim Downes is the Founder of Blueprint CFO, a future-focused accounting & CFO services firm based in Southern California. A veteran outsourced Chief Financial Officer (CFO) and financial advisor, Jim Downes has served business owners and management teams for over 20 years. He has worked with over 200 companies, specializing in fractional CFO activities and as a CTP (Certified Turnaround Professional). Jim began his career as a Certified Public Accountant at Plante Moran CPAs, the 14th largest CPA firm in the US. Beginning as a part-time CFO before becoming a full-time Vice President, Jim helped launch his first outsourced accounting client, Urban Science, an automotive technology/consulting firm, in 1985. During his tenure, the company grew from less than $1 million to over $50 million in annual sales, winning the Ernst and Young Entrepreneur of the Year award in 2001. Jim founded the Acumen Group, committed to providing part-time CFO services and financial advice to middle-market and privately held businesses in 2001. In 2007, he joined BBK, an international turnaround consulting firm, as Director. During the Great Recession, he positively transformed numerous businesses facing financial distress and severe cash shortages. Jim relocated to California in 2009 to open BBK's Los Angeles office. When KPMG acquired the company in 2014, he was named Director of Restructuring and Turnaround Services for the West Coast. At the same time, he also became a nationally certified turnaround professional (CTP). Recently, Jim completed the training to become a Professional Implementer of the EOS (Entrepreneur's Operating System). Jim has been certified in Revenue Science and the CRO Thinking methodology through his training with the Revenue Game LLC. Jim's enduring passion for working with business owners seeking to build great companies led him to open Blueprint CFO in 2019. A forward-looking strategist, Jim and his team provide a competitive advantage over typical CFOs. Leveraging data, they go beyond the numbers to make their clients more profitable. Learn more at www.blueprintcfo.com. Connect with Jim: www.BlueprintCFO.com Website: www.blueprintcfo.com Instagram: https://www.instagram.com/blueprintcfo/ LinkedIn Page: https://www.linkedin.com/company/blueprintcfo/ LinkedIn Profile: https://www.linkedin.com/in/6criticalfunctions/ Twitter: https://www.twitter.com/blueprintcfo/ Facebook: https://www.facebook.com/blueprintcfo/ YouTube: https://www.youtube.com/channel/UCN0WE0cdI3sZxssaPVPUwvQ ▼ ▼ Connect with Rose Davidson: Website: https://talkingwiththeexperts.com Follow me on Facebook: https://www.facebook.com/onlineeventmanagerandpodcasttrainer/ Leave a Google review: https://g.page/r/CaXk7K3UlEhzEBI/review Leave a review on iTunes: https://podcasts.apple.com/au/podcast/talking-with-the-experts/id1549141963 SUBSCRIBE to YouTube: https://www.youtube.com/channel/UCkM5n5QJhnNAmUiMzii73wQ https://youtube.com/@talkingwiththeexpertsvodcast FOLLOW on SoundCloud: https://soundcloud.com/talking-with-the-experts Give me 15 minutes of your time, and I'll explain how you can start a podcast, https://calendly.com/rose-davidson/podcast-creation-15-minutes. I look forward to hearing from you. Buy me a Coffee: https://www.buymeacoffee.com/rosesdavidson Become a patron: https://www.patreon.com/talkingwiththeexperts #business #entrepreneur #podcastepisode #podcastguest #podcasting #podcastinterview #podcasts #podcastshow #rosedavidson #smallbusiness #talkingwiththeexperts #video #vodcast

百车全说丨当相声听的汽车电台
2022年097期:极氪009,到底卖给谁?

百车全说丨当相声听的汽车电台

Play Episode Listen Later Nov 30, 2022 52:41


※ 投稿邮箱:418150505@qq.com※ 本文章发布于订阅号:百车全说,订阅号阅读更加方便,欢迎关注。前30分钟聊极氪009,后面聊的不可言表。今天这期节目咱们聊聊前不久刚上市的极氪009。这是一款纯电MPV,售价49.9-58.8万。可能很多听友觉得夸张,什么人会花50多万去买一台纯电动的MPV呢?难不成又是给富豪们造的一台大玩具?毕竟纯电车型都有续航焦虑,这个定价普通家庭消费不起,商用领域又缺少实用性。其实,电动车的使用非常场景化,今天这期节目咱们就聊聊这款非常特别的车型,纯电动的极氪009,它到底有哪些亮点和槽点?希望为大家在今后选车换车的时候,能有一些启发。极氪009定价贵不贵?我觉得吉利不可能没有做过调研,在纯电动消费领域,目前最主流的车型是SUV,大家可以看到特斯拉上市ModelY之后,销量一直不低,甚至还抢走了自家Model 3的客户。蔚来上市这么多年,从ES8、ES7、ES6到EC6全都是SUV车型,直到最近2年才推出了轿车产品ET7和ET5。如果理想也算是增程式电动车的话,从理想ONE到现如今的理想L9、L8、L7,也全都是SUV车型。那么,极氪为什么偏偏不做SUV呢?第一款上市的时极氪001,轿跑造型的电动车,现在上市的极氪009,又是极其冷门的纯电动MPV。其实我觉得这应该是从品牌营销的角度出发,毕竟现如今市场上纯电动SUV实在是太多了,从10几万就能买到的小鹏G3,到80万一台的高合HiPhi X,每一个档位都挤进来无数的玩家。极氪作为一个新品牌,想在这个领域杀出一条血路,难度可想而知。另一方面,极氪的定位明显是要高于吉利的,所以产品的定位和定价起步还不能低。因此,第一款极氪001入门就接近30万,满配要超40万,特斯拉Model 3后驱版才27万多,高性能版定价34万多。明显极氪001根本不是用低价来吸引客户,而是把配置、性能、设计都拉满,就是硬刚对手,至于喜不喜欢,那只能是“我尽管努力,剩下的交给天意”了。不过好在,极氪001开局比较顺利,大部分媒体都给出了很高评价,市场上订单也接近破万。但随着而来的负面新闻也开始增多,比如大量客户反馈车机BUG严重, 正常使用也会黑屏死机,辅助驾驶也经常不能使用。今年7月极氪官方宣布,为所有极氪001车主免费更换8155芯片,而且在7月19日之后推送极氪OS 3.0版本,新增29项功能,优化体验204项。虽然极氪怒砸3个亿真心诚意想解决这一问题,车主一开始也是直呼良心。但是,没过多久大家发现,该有的系统BUG还是会出现,这就又出现了不少网络上的投诉维权案例。我觉得极氪001作为极氪的第一款产品,如果打分的话,应该给到80分左右。硬件不差,驾乘体验也没有问题,但是这套车机可能从底层就得推倒重建,这可是个大工程。甚至有很多极氪001的客户都在期待,极氪009上市之后,会不会推送一个新版本给到极氪001车主同步更新呢?谁知,并没有收到任何OTA升级的消息,反过来看,我们只能祝愿极氪009的车机匹配更完善一些,别出现极氪001上面的类似问题。对于大多数家庭来讲,哪怕是买豪华品牌,30多万的奔驰C、宝马3系就算过上品质生活了,如果预算再充足一些,买40多万的奔驰E级、宝马5系,说明你的小日子过得已经十分滋润了。再往上,7、80万甚至百万级豪车,不是说富裕家庭买不起,而是根本没必要。奔驰S、宝马7系更多的是符号化的意义,买C级、E级、3系、5系的客户,主要还是针对品牌、空间、动力、配置各方面都想要有改善。而到了7系、S级这种,没几个客户是冲着空间和配置去的,而是他们的生意做到了这个阶段,就差这么一台车彰显一下身份而已。那么极氪009售价49.9-58.8万,你猛然一看,觉得很贵。但是仔细想想,蔚来的首款产品ES8售价不也是49.6-65.6万吗?为什么蔚来ES8没有那么多人说贵,而极氪009大家就不接受这个价格呢?其实,说到底还是“锚定效应”的问题。ES8在上市之前,已经通过媒体把价值千万的EP9炒的人尽皆知,几乎所有人都认定这是一个定位高端的电动车品牌,蔚来顺势推出ES8,再提供当初市场上还没人玩的换电服务,以及后来圈了一波粉丝的私域流量玩法,甚至有人觉得ES8就是进入高净值社群的一张门票。这台车被营销手法赋予的软实力,我曾经有一起节目专门分析过。那么反过来看 ,极氪009的定价被人吐槽太贵,是不是在软实力的包装上缺一些火候?所有对外宣传都是针对产品本身,然而纯电动MPV这个概念,本就是让大多数人比较难以接受的。就好比我一日三餐已经习惯了吃米饭,但你告诉我生酮饮食更健康,你可以改变一下饮食习惯。说实话,除非我对身材管理有非常明确的目的性,否则我绝对不可能坚持这种生活方式。因此,纯电MPV到底是哪类人在买?它对比燃油和混动MPV,到底有哪些突显优势的使用场景?这些都需要厂家用生动的案例来教育客户,而不是“哐啷”把这款产品丢市场上,然后告诉大家我可是使了劲地堆了很多料,你看完这么有诚意,不来一台吗?极氪009到底怎么样?极氪的发布会我也看了,CEO提出了5个所谓的灵魂拷问。第一个问题:为什么MPV都长着千篇一律相似的前脸?结果极氪009设计出了一个极富争议的前脸。当然,如今汽车圈的设计风格,我觉得有争议反而是好事,关键是看你这个品牌能不能Hold得住争议。就比如宝马新一代车型改大鼻孔的时候,大家也有争议,最后4系该加价还不是加价?奔驰改三角眼的时候也是争议很大,如今该没有优惠依然没有优惠。第二个问题:MPV的安全为什么很难做?大家都知道某百万级豪华MPV碰撞后起火,车门打不开的事故。MPV不同于其他车型,经常路上经过的一辆MPV,里面坐着是一家甚至两家的三代人。这种把鸡蛋放在一个篮子里的车型,对安全有更苛刻的要求是理所应当的。所以极氪009用了全球量产最大一体式压铸后端铝制车身,还把第三排头枕到车尾玻璃的距离设计得更远。除了被动安全,主动安全配置也都拉满。官方想表达的意思就是,咱们真的是砸了真金白银去搞安全性了。不过这些其实说不说都没有一次碰撞测试来得更有意义,现在不都喜欢玩双车对撞吗?前不久非常火的一个视频,岚图梦想家对撞丰田埃尔法,最后主持人以一句“丰田完蛋了”结束。这个热点不蹭白不蹭,咱就用极氪009对撞岚图梦想家,如果赢了,咱们主持人也可以用一句“岚图要努力了”结束。第三、第四个问题:为何大家都在追求MPV的舒适性?大多数人认为买MPV就是买两个沙发,而对于第三排的体验厂家和客户都没有太过重视。我本以为极氪009的第三排座椅能有什么黑科技,但是听了半天,发现也就是第三排与前两排一样都是SoftNAPPA真皮,靠背可以180°躺平,其他方面也没什么突出特点了。我觉得除非二排三排都是头等舱座椅,否则都别提二三排座椅。但是二三排都头等舱座椅,除了车身尺寸得再扩大一圈之外,实际体验也并不一定会更好。毕竟一台车上不可能同时坐四个身份地位完全一致的老板,家庭地位还分高低呢。况且,航空座椅只是坐着舒服,它并不能完全折叠放倒,这就导致后备箱想要扩容空间,第三排如果是航空座椅,那根本扩容不了。不过极氪009二排带按摩,驾驶座头枕带YAMAHA音响,车舱中顶还要15.6英寸大屏幕,甚至还要隐藏式小桌板,全车有18个独立空调电机,10个智能电动出风口,空调温度还能再侧面门板上进行调节,我相信这点创新应该会让客户眼前一亮,这有些类似中央空调的感觉了。关于二三排座椅,还要一个争议很大的点。极氪009为了让二排座椅更宽大舒适,就取消了中央通道,因此如果要进入第三排,需要一键位移,让二排滑动到最前端,靠背前倾,这样就让出了进出三排的空间。但这样的前提是,三排先上乘客,二排乘客再进入。当然,让老板在车外站一会儿也没有问题。可关键是家里如果有宝宝,又需要安装儿童座椅怎么办?其实,我觉得这个问题也可以解决。因为你不可能把二排两个航空座椅全部按上儿童座椅,你可以安装在主驾驶后方的座椅,平时上下车通常都是从右侧车门下车。即使有两个孩子,另一个儿童座椅,大概率也是安装在主驾驶这一侧的第三排位置。还有五个问题:MPV是不是一定无法做到好的操控?其实这个问题是为极氪009,或者说是为纯电动MPV量身定制的,这明显是有些小心机了。市面上纯电中大型MPV本就不多,除了极氪009,还有岚图梦想家、腾势D9、荣威iMAX8 EV,以及上汽大通MAXUS MIFA 9。这里竞争对手本就不多,而且各个加速都不慢。所以很明显,这问题得从燃油和日系混动车里找答案。极氪009零百加速4秒5,号称MPV里唯一进入4秒俱乐部的车型。WE版续CLTC续航702km,ME版续航822km,还标配空气悬挂,CDD电磁减震系统,并且是前双叉臂,后多连杆全铝独立悬架。配置看上去很顶,但是我又有疑问了,别克GL8卖的好是因为它提速快吗?当然,任何车在操控性上又优势,你不能说它是缺点。但是MPV想要面面俱到,是不切实际的。我们感觉买MPV的车主都一样,要么公司接待客户,要么家里二娃三娃。实际上,每个买MPV的客户,都能对市面上任何一款MPV挑出各种毛病。比如,觉得极氪009没有二排中央过道,觉得腾势D9的二排坐姿偏高,觉得大众威然的三排靠背角度不合理,觉得除嘉华外二三排私密性不够好,觉得赛纳的第三排横向空间偏小, 甚至还要觉得三排通风加热都很重要,市面上也就GL8艾威亚,还要上汽大通MAXUS MIFA 9有这个功能。但是我想问一句,客户会因为这些小细节就放弃一款车吗?大概率不会,他们最终看的还是口碑、保值率、基础的实用性,大部分人还是相信保有量大,能见度高的MPV,起码买这种工具车,采坑的风险比较小。配置该怎么选?关于极氪009这款车本身,如果从购买角度分析,我更偏向于直接冲顶配。毕竟无法更换电池包,WE和ME版两个配置差价11万,就是续航里程相差120km。如果你觉得这11万换来120km续航根本不值,五菱红光MINIEV同样1-200km续航才卖3-4万。当然价格不能这么算,你在家里泡杯速溶咖啡,跟去星巴克点杯咖啡,价格和体验能一样吗?况且,当你就差那百来公里没电回不了公司,回不了家,带着一车去找充电桩,这种尴尬场面遇到一次,你都会后悔当初没有加这11万直接上顶配。虽然说顶配也就多了24度电(WE版116度,ME版140度)。而在颜色选择上就看个人喜好了,我各人不太喜欢方方正正的镀铬进气格栅,造型特别像厨房里用来削土豆的刨子。实际上极氪009的前格栅还有车身同色版,如果是我,我会选择黑色车漆+同色版本的进气格栅,而且同色版本的进气格栅是免费,镀铬的还需要加8000块。极氪009的长宽高分别为5209/2024/1848毫米,轴距3205毫米,车重接近3吨。这个尺寸和腾势D9、蓝图梦想家差不多。而且相比埃尔法,宽度多了174毫米,轴距长了2205毫米。对比别克GL8,宽度多了 146毫米,轴距长了117毫米。空间体验,大家其实去试一次就明白了。而在内饰方面,极氪009和极氪001的布局大体一致,10.25英寸液晶仪表+15.4英寸中控屏的组合。在车机上,009和001也是出奇的一致,搭载了一套ZEEKR OS系统,配备高通骁龙8155芯片、5G车联网。同时,009的后排还配备了一块15.6英寸的中央顶屏,这块屏幕内置会议模式,在车内可以完成线上会议。而且还支持SWITCH游戏机接入和手机无线投屏等功能,所以能在车上玩SWITCH不再是理想独有。按照官方的说法,极氪009宜商宜家。009目前的两个版本都是2+2+2的6座布局,据说六个座椅全部标配了SoftNAPPA中间加了减震层,然后又加了层海绵,但是我们编辑去试驾体验回来,感觉坐起来并没有什么特别之处,可能需要跑长途,才能体会到这个座椅的好处。第二排座椅还有3挡强度可选、5种模式的按摩功能以及座椅记忆功能,并且电动腿托支持电动四向最大65°调节,最大长度50cm,几乎就是平躺的姿势。不过,我们前面提到的第二排小桌板,是不能前后伸缩的。对于009的空间,理想的创始人李想之前还发微博怒怼009说“官图中的第三排乘客怎么感觉蹲在了后备箱,三排座椅好像没了。”吉利副总裁杨学良还回复李想,“别瞎说,没蹲后备箱。这是二排调到最后的三排空间,欢迎亲自对比体验呀。”客观地说,009定位中大型MPV,车长5米2,轴距3米2,所以空间上绝对不是问题。只是那个官图太夸张了一些。不过根据实际操作来看,二排的滑轨一直延伸到三排,如果将二排调到最后,靠背会紧贴三排坐垫,所以是坐不了人的。因此那张官图大概率只是因为角度或者焦距的不同,营造出了二排空间巨大的感觉。不过它本身的空间确实很大,不管是家用还是商用绝对够了。那张照片只有两种可能性,一是广角镜头,把二排空间放大了。二是二排的确移动到底了,第三排男士是盘腿坐在座椅上的。在动力上,009用的和001一样的双电机四驱系统,前后为双永磁同步电机,综合最大马力544匹,最大扭矩686牛·米,官方公布的0-100公里/小时加速时间为4.5秒。一个3吨的大MPV百公里加速仅仅只要4.5秒,确实有点耸人听闻。在续航方面,WE版搭载容量为116度的电池,CLTC工况续航里程为702公里;而搭载电池容量为140千瓦时CTP 3.0麒麟电池的 ME版,CLTC续航里程822公里,所以即便是打7这也有570多公里的实际续航。在智能驾驶辅助上,极氪009搭载了ZEEKR ADL2级驾驶辅助系统,包括带车道居中保持的跟车巡航、自动变道以及遥控泊车等功能。但是很遗憾,没有一步到位给到激光雷达。在购车权益上,没有整车终身质保了,而是三电系统终身质保,整车6年或15万公里质保。此外,免费救援、终身流量、中央吸顶屏的一年影视会员。其实我觉得极氪009更适合特定场景下的某些商业用途,比如我每次去机场停车,都会选择机场附近的一些私人开的停车场,这些停车场停一天的费用才20-30元,非常便宜。每次跟老板约好时间,我开到停车到场之后,他就会开车送我去航站楼。这两年,机场附近停车场接送用车全都换成了电动车。因为他们一天就要点对点跑3-4百公里,用电动车可以省下一大笔油费,以及保养维修的费用。当然这部分小老板,是肯定不会用极氪009这么豪华的车来接送客户的。但是,类似这样的机场周边酒店,是不是会考虑购入这类车型呢?同样这种两点一线接送客户的场景,我相信在现实生活中还是会有很多的。而纯电MPV市场本就没有几款车型可选,极氪这个品牌对于不少人来说,有吉利这种成熟厂家的背书,又有可以看得见的设计和配置,应该还是会有人买单的。而那些原本就考虑别克GL8、世纪、赛纳、奥德赛、艾力绅和广汽传祺M8的客户,我觉得大概率不会转买极氪009,这不是价钱高低的问题,而是关乎到今后使用的便利性和实用性。对于长途旅途且行程可能随时会变的人来说,用纯电动车跑长途面临的就是充电会占用太多时间,影响出行效率。所以我一直在想,为什么主打换电的蔚来,为什么不出一款MPV呢?另外还有一点值得注意,那就是部分用户乘坐纯电动车辆会有不适,我媳妇就是这样的人。每次出门都不愿意坐我的电动车,说坐在后排心慌想吐。要知道,我这车加速并不快,我自认为开车也还算温柔。但是没办法,电动车的起步响应几乎是无延迟的,而松开电门又会有制动力回收。你开车的人习惯了倒还好,但是坐在后排的乘客,可能真会有些不适。如果大家经常打网约车,也可以聊聊打到的燃油车与电动车,坐在后排的不同感受。我还有一个推测,就是极氪目前的两款产品,主要任务是为了拔高品牌的高度,特别是极氪009,卖多少不重要,重要的是把高端形象立起来,这也是为后期的车型铺路。比如后期大概率会出纯电单电机版,因为MPV没必要这么快的加速,即便百公里加速10秒,只要价格到位,绝对不愁卖。甚至后期还会推出增程版来进一步拉低售价,因为增程版只需要一块小电池+油箱,就可以无限续航,这一下子就解决了续航和成本两大问题,那时候才是真正出手的时候。此外,极氪009我觉得还是要有一个清晰的产品定位,像别克世纪或者理想L9那样,商用就商用,主攻老板;家用就家用,主攻奶爸。有舍才有得,虽然短期内销量可能会受影响,但是从长远角度来看,一旦名气打出去,形象立住了,后期的销量才不用愁。写在最后现如今,各大品牌争相推出MPV,二胎、三胎政策放开是一方面。另一方面,MPV市场之前几乎都快被那几款合资车给垄断了,尤其是别克GL8、传祺M8、奥德赛、艾力绅,赛纳等等。这些车还可以经过后期的改装,换装头等舱座椅、木地板、大屏幕和娱乐系统,这条后装生产线已经非常成熟。像这种成本不高、改动难度也不大的活,你说主机厂看了能不眼红?这种蛋糕怎能留给这种后期的小厂?所以各大品牌看到这块蛋糕之后争先恐后的推出MPV产品。再加上MPV这种大型车又大又重,如果是纯燃油那肯定很费油,你看GL8就知道了,百公里13-15个油都是常规操作。所以MPV+新能源那就是绝配,动力又足,成本又低,消费者自然愿意买。但是现在处于MPV的发展中阶段,后期还会有更多的MPV车型。所以只要不是刚需,我建议还是再等等,因为真正的好戏还在后面。可以添加微信46415254加入我们的社群音频图文更新在订阅号: 百车全说每期抽三条留言,每人赠168元的“芥末绿”燃油添加剂一瓶点击订阅,每周三,周六更新会有提醒新听友可以搜索:百车全说2014,百车全说2015,百车全说2016,往期300多个小时的节目可供收听

Anaheim Calling: for Anaheim Ducks fans
Verbeek Speaks, Ducks Quarter Season Review

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Nov 29, 2022 96:29


On this episode, we break down Verbeek's comments on the Beeker and we dive into a quarter-season review of the Ducks.Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpodSubscribe to our live Twitch stream twitch.tv/crashthepondBecome a Patreon patron: patreon.com/crashthepondCheck out the video version of the podcast: youtube.com/crashthepondOr leave us a review on Apple PodcastsThanks for listening!Timestamps:Verbeek podcast Time:00:00:00Quick game recaps Time: 00:18:00Quarter season review Time: 00:34:00Q and A 1:06:00

Climbing The Pocket
Vikings vs Patriots | The Final Score

Climbing The Pocket

Play Episode Listen Later Nov 25, 2022 36:52


On this episode of Climbing The Pocket's “The Final Score”, we react with you! It is Thanksgiving and the New England Patriots are visiting the Minnesota Vikings. Are you full of food? Has the turkey put you into a food coma? Or is this game going back and forth to where it is tied in the first half got you excited? It should have, and chock one up for the local cardiologist. LOL. Will find out if Kirk Cousins can keep up his uptempo play without throwing another interception. He did and even got more fired up. Fired up Kirk is a better Kirk Cousins. The great Justin Jefferson has already broken the three-season pass-reception record for the NFL. How much more yardage or touchdowns is he going to add for the whole game? He finished with 139 yards and 1 touchdown. Adam Thielen is third on the Vikings' all-time pass reception list and continues to add to it. He had a great catch in the end zone as well. Dalvin Cook seems to be running pretty well, will that continue or get better in the second half? Not really. Is the defense going to pick their end of the bargain up? Only at the very end, and that was enough. They seem to be very few pressures in the first half. Will they get more in the second? Late in game, yes, when Mac Jones needed deeper drop backs and couldn't get away with his quick throws. Can the Vikings pull off the win and go to 9-2? They sure did in another 4th quarter comeback to win 33-26 over the Patriots. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jonas, Flip, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/iWVS8NfNPRU At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

DH Unplugged
DHUnplugged #630: Cheering Layoffs?

DH Unplugged

Play Episode Listen Later Nov 23, 2022 53:34


Companies are announcing layoffs and market cheer! Crypto craziness - FTX ripples throughout industry. End of year game plan - CTP update and more. PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter Warm Up - Big Moves - Bets are For Less Hawkish - Nasty Action in Bitcoin/Coins - Weird moves at Disney - Crazy Weather in NorthEast - Reminder of the CTP going on right now.... Market Update - Short Week, Wednesday Big Day ECO (FOMC Minutes) - Headwinds keep piling on - nothing recedes these days - OPEC news of production increase - then denial - Crypto Saga continues SERVER UPDATE - ALL MOVED, CHECKED ALL GOOD TO GO Turkey Recipe? Dinner Plans? - PICKLE FEST Weather Update - Snowfall of more than 6 feet in western New York state prompted local officials on Saturday to further restrict road travel and forced airlines to cancel flights in the Buffalo area, just ahead of the busy Thanksgiving holiday week. Twitter/MUSK - Not talking about - gotten too weird - Although TSLA at 2-year low price - Any predictions about Twitter's future? - Oh, and Trump snubs Twitter after Reinstatement (By Poll?) World Cup - Alcohol BANNED from stadium last minute - World Jewish Congress said meals cooked to Jewish dietary rules and public prayer have been banned during tournament - It is all about $$$$ - More than ever.... Why More Nuclear Talk? - What is with this? - The head of Russia's state-run atomic energy agency, Rosatom, warned on Monday there was a risk of a nuclear accident at the Zaporizhzhia nuclear power plant, Europe's largest, following renewed shelling over the weekend. Oil Prices - Oil prices dropped to trade near two-month lows on Monday - Dropped to $75.25 for a moment then was bought on recent double-bottom - "Apart from the weakened demand outlook due to China's COVID curbs, a rebound in the U.S. dollar today is also a bearish factor for oil prices," said Tina Teng, a CMC Markets analyst. - More importantly, OPEC is discussing increasing production by 500,000 barrels per day OPEC Reversal - OPEC news that they are going to increase production by 500,000 barrels per day. - Quickly reverses after oil prices plunge OPEC MOVES Now to China - COVID deaths - first time being reported in a while - Lockdowns - roaming - Numbers climbing and big concern that this is going to keep the slowdown around the globe - Inflationary - to a degree and deflationary at the same time - China held their interest rates steady - they are having a tough time Over to South Korea - South Korea's exports for the first 20 days of November shrank 16.7% from the same period a year ago, dragged down by weak demand for chips and from China, customs agency data showed on Monday. - The country's imports fell 5.5%, bringing the trade balance to a $4.42 billion deficit, on track for an eighth straight month in the red. - Shipments to China dropped 28.3%, while those to the United States and European Union were up 11.0% and down 1.5%, respectively. - By product, sales of semiconductors fell 29.4% and wireless communication devices lost 20.6%, but those of cars and petroleum products gained 28.6% and 16.1% each. ---- Remember the Chip shortage? Peak Oil? Note those kind of events....... Not What You Want - Philips , which has been struggling with a major recall of ventilators, on Monday flagged further problems with some machines it has previously replaced - The FDA said the company had notified it that the sound abatement foam could come loose in some refurbished models, "lowering the inspiratory pressure". - In addition, trace amounts of particulate matter were found in air pathways of some reworked ventilator...

Anaheim Calling: for Anaheim Ducks fans
Ducks Trade Rumors, St. Louis Recap, Possible Changes

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Nov 22, 2022 78:08


On this episode we discuss the latest reports from Elliotte Friedman that the Ducks could soon be active on the trade market, recap the Monday night tilt in St. Louis, and potential changes the Ducks could make to right the ship. Enjoy!Support the show:Get 10% OFF tickets with promo code "CTP" at 714tickets.comSubscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Climbing The Pocket
Vikings vs Cowboys | The Final Score

Climbing The Pocket

Play Episode Listen Later Nov 21, 2022 31:53


On this episode of Climbing The Pocket's “The Final Score”, we react with you! Your Minnesota Vikings are coming off a big win against the Buffalo Bills and now face the Dallas Cowboys. Will this be a letdown game? It sure looked like it and what could go wrong, did. After the first half, it looks that way. Starting with a third-play strip sack and a fumble was not good. Not to worry, Dallas ended up with a total of 7 sacks and the O-line couldn't answer. “Onto the Patriots”, to channel our inner Bill Belichick. Knowing that the Cowboys started out fast and furious in the first half, can the Vikings come back? Not a chance. They were trailing 23-3 at the half. Can they stiffen and stop Tony Pollard from eating their lunch? No, they didn't when he 189 yards all on his own and the Vikings offense only had 183. It looks like Christian Darrisaw has gone out with another concussion. Not good. Then later we saw that Ezra Cleveland had some undisclosed injury. After some good throws by Kirk Cousins, can he complete more? Not much. Justin Jefferson only has two catches in the first half, will he get more in the second? He got only one more. Can the Vikings make their biggest comeback of the season? Negative, as we'd say in the military. Join us and find out. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jayson, Matt, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/nECed0mHUw8 At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
Where Do the Ducks Go From Here?

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Nov 15, 2022


On this episode, we discuss what happens next for the Ducks after their difficult start to the season. Is it time to look to the future, make benches behind the bench, or let things play out?Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpod Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Conspiracy Therapy
Episode 270: 270 - Rodney Alcala

Conspiracy Therapy

Play Episode Listen Later Nov 14, 2022 57:18


It's date night with the CTP crew!@BeerCityMedia @ConspiracyTshow @RyanHarig @GameAndPod @The_illumimommyhttps://open.spotify.com/artist/0iUvxd5lUQjZ6KbjOWCLPO?si=8G__bYvuRBSQVh4jcfOHOghttps://www.patreon.com/beercitymediapodcasts https://bosscoshoup.bandcamp.com/ https://glassfield.bandcamp.com/

Climbing The Pocket
Vikings vs Bills - Greatest Regular Season Football Game Ever!

Climbing The Pocket

Play Episode Listen Later Nov 14, 2022 99:06


On Climbing The Pocket's end of the game show, The Final Score, we react with you! Was that the greatest regular season football game ever? The Minnesota Vikings vs Buffalo Bills and it will be the biggest test yet for this team. It sure was and turned into the heavyweight battle of the century. The question heading into today was can the Vikings continue to improve their winning record? They did in a game that had our hearts racing. To come back from 17 points down in the 4th quarter, to almost win it in regulation but take it to overtime was amazing. Will Kirk Cousins make the difference again? When it counts. He wasn't the only one, was he? Justin Jefferson had a monster game and a Hall of Fame catch that left no doubt he was the best wide receiver on the field. This was despite Stefon Diggs having a very productive game as well. Then Patrick Peterson sealed the dramatic win with his second interception of the day. It was a heart-stopping affair, but with the 33-30 victory, your Vikings improved to 8-1. Watch and react with us! 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jayson, Matt, and Dave will be here. Did you like what you saw? Fan with us!!! Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/W0vuEWVaw7k At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

CHEST Pulse
A Conversation With Center for Tobacco Products Director, Dr. Brian King

CHEST Pulse

Play Episode Listen Later Nov 9, 2022 37:16


Join Frank T. Leone, MD, MS, FCCP, Chair of CHEST's Tobacco/Vaping Work Group, for an interview with Brian King, PhD, MPH, the recently appointed Director of the Center for Tobacco Products (CTP). The CTP is the Food and Drug Administration arm responsible for carrying out the law commonly known as the Tobacco Control Act, which gave the agency broad authority to regulate the manufacturing, distribution, and marketing of tobacco products.  Their conversation touches on key priorities for CTP, the enforcement capacity of the agency, updates on the evaluation of electronic cigarettes, and the goals of reducing nicotine content in cigarettes. Finally, Dr. King shares advice on how you—a member of the chest medicine community—can become more engaged in these types of issues.  CHEST's advocacy mission  CHEST supports the development of policies and regulatory or legislative actions that improve access to health, particularly around tobacco and vaping, oxygen access, pulmonary rehabilitation, and noninvasive ventilation. Read about our advocacy priorities and statements.  LEARN MORE ABOUT CHEST ADVOCACY » 

DH Unplugged
DHUnplugged #628: Lame Ducks/Schmucks

DH Unplugged

Play Episode Listen Later Nov 9, 2022 61:16


Crypto crash part XXIVV. The lesson is now clear - never put your company name on a sports facility. The Dems going to have a tough day - Biden concedes that a change is coming. Markets are caught between earnings downgrades and seasonal benefits - which way will it go? PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter Warm Up - Election Day! Lots looking for split govy! - Glitch on the server - last CTP may be a problem - All about Musk - All of the time - gotta keep relevant - Employment Report - Can't stop never gonna stop! - New Server Up - lots of dev time on this migration... Market Update - Starting out November on the wrong foot - Who Will run in 2024? Markets trying to sniff out the playbook - China's stock market rally hard! - False hopes? - Incredible - FTX now needs bailout IMPORTANT UPDATE - TrendTracker: S&P 500 earnings are up 2.2% yr/yr in Q3, but they are now expected to fall 1% in Q4 - FactSet - "On June 30, the estimated earnings growth rate for Q4 2022 was 9.1%. By September 30, the estimated earnings growth rate had fallen to 3.9%. Today, the estimated earnings decline is -1.0%." - Earnings are currently expected to return to yr/yr growth in Q1 and accelerate throughout 2023, coming in at ~5% growth for the year (down from nearly 10% not long ago). - Those estimates still seem relatively optimistic/stale if the economy continues to soften as many economists expect. - Estimates for 2023 seem likely to come down further when companies will give initial guidance for the year with Q4 results in Jan-March. Earnings Slowing BUT...... - According to the historical trends during years of mid-term elections - Gridlock on Capitol Hill would be supportive of risk assets. Being forced to compromise serves to moderate the more extreme inclinations of each party, providing a more stable policy backdrop for investors. -- -The data supports this. - US equities have averaged annual gains of 12.9% when a president has had to contend with a split Congress. - This compares with a more modest increase of 6.7% when a Democratic president has controlled both chambers. Stock Trends - Mid-Terms Twitter Chaos - $8 Blue Checkmark - what is the point? - Flip flop - now $8 checkmark waits until after the election - Job cuts - massive headcount reduction (3,600- then a reversal a few days later - Blue Checkmark warning - imposters will get banned for life ---- So fake news and hate is okay, but just don't pose as Elon? What a joke! - Musk wrote on Sunday that, moving forward, Twitter will now permanently suspend impersonators' accounts without warning if they are not clearly labeled as parody. - Advertisers pulling out "temporarily" - - Musk uses it as a great way to make excuse for layoffs - even though layoffs were happening before the advertiser embargo Crypto - And that was that - FTX has liquidity crunch after massive withdrawals - Sam Bankman Fried panics and sells all to Binance - Binance will back all transactions - Remember Fried stepped in on some of the "stablecoin" deals hoping that they could save them - Fried has been called the last resort for many crypto - the new JP Morgan -- - The FTX co-founder is on the brink of a 94% wealth wipeout - Major coins were getting crushed early in the day Tuesday on the liquidity scare - - > Rally with this news - - Seems that this whole industry has been build on hope and greed rather than any substantive math/finance Apple - Finally Succumbs - Taiwan's Foxconn, Apple Inc's biggest iPhone maker, said on Monday it was working to resume full production at a major plant in China's Zhengzhou as soon as possible that has been hit by COVID-19 curbs,

Climbing The Pocket
Vikings vs Commanders | The Final Score

Climbing The Pocket

Play Episode Listen Later Nov 6, 2022 61:23


The Minnesota Vikings vs Washing Commanders and it will be another test for this team. The question today is can the Vikings continue to improve their winning record on the road in Washington on one of the poorest fields in the NFL? They did. 7-1 Baby!!! Can the offense sustain and score early and often? No, but they did come back in the 4th quarter down 10 points to get the win. Can they break that 30 point mark again this week? They did not, but didn't need to. Can a defense hold up its end of the bargain and keep Washington from scoring lots of points? They held Taylor Heinicke and his favorite receiver, Terry McLaurin to just 17 points. We used to call that the Mendoza line. 17 points and below over 95% of the time leads to a Vikings win. It did again today. Is Justin Jefferson able to make his name known and resume leading the league once again? He had 115 receiving yards, another 10 on the ground, plus aa TD. Can the new guy, TJ Hockenson establish himself as a vital part of the Minnesota Vikings offense? He sure did! 9 catches, no drops for 70 yards. More importantly, can he establish that chemistry that we know Kirk Cousins loves to have between himself and his tight end? It sure looks that way! That should make us all happy. All these questions, and more as we react at the end of the game, in the final two minutes, with Climbing The Pocket's ‘The Final Score.' Join us and react to what you are watching in the final 2:00 of the game. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jayson, Matt, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/0-sHE0OqC_A At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com That's Bad Ass Wood Art - https://www.thatsbadasswoodart.com/ Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
Ducks Back in the Win Column, Drysdale Injured

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Nov 1, 2022 83:27


On this episode, we discuss the Ducks getting back to their winning ways with an exciting overtime win against Toronto, Jamie Drysdale being out for 4-6 months, Trevor Zegras's greatness, and much more!Support the show:Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpod Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Climbing The Pocket
Vikings vs Cardinals | The Final Score

Climbing The Pocket

Play Episode Listen Later Oct 30, 2022 52:37


The Minnesota Vikings vs Arizona Cardinals and it will be another test for this team. Can they continue to find a way to win? They did. Will they play a more complete game where the offense, defense, and special teams work hand in hand to compliment each other? They did. Can Kirk Cousins have a big day against a defense that is known to weak against the pass but strong against the run? He had a fair game 24/36 and 2 TDs in the air and 22 yards and a TD on the ground. We will have to wait until the Final Score to know for sure. Join us and react to what you are watching in the final 2:00 of the game. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jayson, Matt, and Dave will be here. Did you like what you saw? Fan with us!!! Guest Jonas Stärk @JonasStaerk. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew and @thatsbadassmn. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/AU9hUaZJZa8 At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

SWFL Business Podcast
32: Anthony Tumbarello from CTP

SWFL Business Podcast

Play Episode Listen Later Oct 27, 2022 39:25


"If you're looking to get in shape and do training the right way, CTP, that's where everybody's going." Welcome to the SWFL Business Podcast, where we interview business owners in the Southwest Florida area to learn about their business and where they're heading. Today's guest is Anthony Tumbarello from CTP. In this episode, Anthony walks us through how he got started as a personal trainer for LA Fitness, before transitioning to a sports performance facility. He talks about the first time he opened his own gym, the mistakes he made in the past, and how these mistakes serve as the guidelines for his business plans. I learned a lot from listening to Anthony talk about his mindset; pay attention and take note of his persistence. I hope you find this interview as informative as I did. Let me know what you think. Visit CTP's website: https://www.ctpswfl.com (https://www.ctpswfl.com) Show CTP some love on Instagram @ctpswfl Show us some love on Instagram @swflpodcasts Listen on Apple Podcasts: https://apple.co/3NYks1F (https://apple.co/3NYks1F) Listen on Spotify: https://spoti.fi/3x1rufI (https://spoti.fi/3x1rufI) Watch on YouTube: https://bit.ly/3j69E3g (https://bit.ly/3j69E3g) Want to be a guest on the show? Book an intro call here: https://calendly.com/cheineproductions/interview-intro (https://calendly.com/cheineproductions/interview-intro) Like what you hear? Want to have your own podcast produced in the Bonita Springs, FL area? Visit www.swflpodcasts.com to learn more.

Anaheim Calling: for Anaheim Ducks fans
Panic Button Time in Anaheim?

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Oct 25, 2022 88:41 Very Popular


On this episode, we discuss the Ducks early season struggles, what has gone wrong, what has gone well, and what changes the team can make to turn things around. Enjoy! Support the show:Get 10% OFF tickets with promo code "CTP" at 714tickets.comSubscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Anaheim Calling: for Anaheim Ducks fans
Ducks Early Season Breakdown

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Oct 19, 2022 88:34 Very Popular


On this episode, we discuss the Ducks' first 4 games of the season, looking at the success of the Zegras-Terry combo, Mason Mctavish's play, John Gibson's performance, and much more! Support the show:Get 25% OFF True Classic with promo code CTP at trueclassictees.com/CTP! Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Climbing The Pocket
Vikings vs Dolphins | The Final Score

Climbing The Pocket

Play Episode Listen Later Oct 16, 2022 40:13


Your Minnesota Vikings have traveled down to a hot and humid South Beach to play the Miami Dolphins. The Vikings are a slight favorite versus Skylar Thompson. Will he make them pay? The defense has opportunities to put pressure on the young QB. Will they? Will Kirktober continue? Kirk Cousins has been hot in October, but will the heat and humidity be too much? Justin Jefferson leads the league in receiving yards. Does he continue to widen his lead? Will Dalvin Cook have another great day in this stadium? He has a history of huge games here. All these questions and yours will be answered on Climbing The Pocket's "The Final Score" streaming live at the final 2-minute warning. 1) Highlights 2) Lowlights 3) Speed round and your questions 4) What's ahead The Final Score [the name for CTP's Postgame show] is here. There are 4 regulars and the occasional guest. The focus will be on you the fan, and how you felt the team did—hopefully racking up the wins in the regular season. Today, Jonas, Tyler, and Dave will be here. Did you like what you saw? #Vikings #TheFinalScore #ClimbingThePocket #VikingsvsDolphins #Dolphins #LakeMonsterBrew #DailyNorseman #SKOL Fan with us!!! Guest Jonas Stärk @JonasStaerk and Tyler Forness @TheRealForno. Regulars Jayson Brown @brownjayson, Flip Mazzi @Flipmazzi, Matt Anderson @MattAnderson_8, and Dave Stefano @Luft_Krigare producing this @Climb_ThePocket's & @DailyNorseman's production partnered with Lake Monster Brewing @LakeMonsterBrew. _____________________________________________________________________________________ Subscribe to us here! - https://www.youtube.com/climbingthepocket Watch the live show here: https://youtu.be/tZTEtcLe-3Y At Facebook: https://www.facebook.com/climbingthepocket/ https://www.facebook.com/thedailynorseman/ Partners: Lake Monster Brewing - https://www.lakemonsterbrewing.com Eastside Jiu-Jitsu Club - https://martialartsorleans.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Anaheim Calling: for Anaheim Ducks fans
Ducks Season Preview, Opening Night Roster Announced

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Oct 11, 2022 84:14 Very Popular


On this episode, we give you a full Ducks season preview and review the freshly announced opening night roster. Enjoy!Support the show:Get 25% OFF True Classic with promo code CTP at trueclassictees.com/CTP!Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpod Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Anaheim Calling: for Anaheim Ducks fans
Ducks Preseason Updates, Roster Cuts, Zegras/Vaakanainen Injuries

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Oct 4, 2022 76:11 Very Popular


On this episode, we discuss the latest updates from the Ducks preseason, how the roster is shaping up, injuries, and much more. Support the show:Get 25% OFF True Classic with promo code CTP at trueclassictees.com/CTP! Go to GreenChef.com/ctp135 and use code ctp135 to get $135 off across 5 boxes including free shipping! Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!

Anaheim Calling: for Anaheim Ducks fans
Ducks Roster Predictions, Captaincy, Preseason News

Anaheim Calling: for Anaheim Ducks fans

Play Episode Listen Later Sep 27, 2022 85:56 Very Popular


On this episode, we discuss Pat Verbeek's comments about the captaincy, what the Ducks forward and defense groups will look like, the latest preseason game, and much more!Support the show:Get 25% OFF True Classic with promo code CTP at trueclassictees.com/CTP!Get 20% OFF @manscaped + Free Shipping with promo code CTP at MANSCAPED.com! #ad #manscapedpod Subscribe to our live Twitch stream twitch.tv/crashthepond Become a Patreon patron: patreon.com/crashthepond Check out the video version of the podcast: youtube.com/crashthepond Or leave us a review on Apple Podcasts Thanks for listening!