Podcasts about st george

Murder doesn't often feature in swimming. In this podcast, two places are linked through this theme: Ballarat and St George's Lake, in Australia, with Wallingford and the River Thames in Oxfordshire, in the UK. Both places have factual andfictional claims to being ‘murder central' in their respective countries. Both have good swimming, and both have murder mysteries attached to their locale. In addition, Ballarat has seen several real-life, gruesome murders in recent years. It shouldn't put you off swimming in its nearby lakes though.

To Wah or not to Wah? Tonight Auckland city hosts international rugby union and a bit of Aussie club rugby league. On the face of it, and with that description, it should be a no-brainer around which fixture should command your attention. The All Blacks are number two in the world, taking on the number three ranked Irish in a game that defends the All Blacks' almost unbelievable unbeaten Eden Park record. 32 years, 52 games without tasting defeat. Impressive. The Warriors, near the top of the NRL ladder (3rd after last night's games) are hosting some roadkill at Mt Smart. The Dragons have all the fire of a cigarette butt at the bottom of a schooner, currently languishing in last place and lucky to be there. Plainly, fans of league will be front and centre with the NRL fixture, fans of union will be fully focused on the Nations Championship clash, but what about the undecided? The All Blacks are frontrunners as their game kicks off at 7:10, the Wahs beatdown commences at 7:35. A nose in front from the All Blacks – then the race tightens. Off the playing surface, Wahs fans are a much more exciting proposition than All Blacks fans. The fear of loss chokes the environment up; the tension crushes the joy of the experience, at the ground and on telly. Rugby fans find it hard to celebrate. League fans are triggered by anything, especially in a crowd, and there's no better crowd in NZ sport than the massive one at Mt Smart. This vibrancy smashes its way out of the telly and spills cheap beer on the floor. On the playing surface, if the Irish win and topple the All Blacks' tower of invincibility, that's not an upset at all. There is a sense that this new look All Blacks team should have enough to hold the Irish at arm's length, but we all know how frail the All Blacks' grasp on significant results have been over the last few years, so losing the Eden Park streak isn't at all out of the question. Do really want to watch that? Conversely, to beat down the emerald barbarians at the gate will bring enormous pride and a sense that Rennie might actually be on to something. Didn't work for Razor though, did it? His 2025 Eden Park South African defiance was remarkable, but the next week we saw possibly the worst performance in All Blacks living memory. As for the Wahs, there's not a comp in the world as close as the NRL. The Dragons are toilet this year, but as we saw on Thursday night when the Bronco whipping boys conjured up a win versus the table topping Panthers, upsets are commonplace. So the Wahs could lose, but they could also open up a can of whup-ass on St George. Still undecided? Try this... is a Warriors team on the way up a better experience than an All Blacks side still trying to find their lost mojo? The choice is yours, whatever you decide, turn off your phone so social media or your mates don't wreck the delayed experience for you.See omnystudio.com/listener for privacy information.

He wasn't an English knight, but actually a Roman soldier, and the dragon didn't appear until centuries later in the medieval period. So what is the origin of the Saint George and the Dragon myth? And why do so many countries - from England to Ethiopia - adopt him as their patron?To sort the fact from the fiction, Dan is joined by Jasmine Elmer, mythologist and author of 'Slay: Ancient legends of female slayers and the hidden mythology of dragons'. They explore the history of dragons from the chaos monsters of ancient Mesopotamia and Egypt to the serpents of Greek mythology, Christian saints' lives and East Asian folklore, as well as the stories of other little-known dragon slayers through history.Produced by Mariana Des Forges and edited by Dougal PatmoreWe need your help! Let us know what you want from Dan Snow's History Hit by filling in our anonymous survey here: https://forms.gle/PvgayWLkWGjYT4St6Dan Snow's History Hit is now available on YouTube! Check it out at: https://www.youtube.com/@DSHHPodcastSign up to History Hit for hundreds of hours of original documentaries, with a new release every week and ad-free podcasts. Sign up at https://www.historyhit.com/subscribe.You can also email the podcast directly at ds.hh@historyhit.com. Hosted on Acast. See acast.com/privacy for more information.

St Georges 4ps - Chat to The High Sheriff Nigel Hartley

St Georges School - Kirsten Absail Update

St Georges School - Dillon RAF Pilot

This week on Bad Dads Film Review, regular programming is temporarily suspended because the World Cup has taken over. No movie this time — instead, Sidey, Dan, Cris and Reegs look ahead to England v Argentina on Wednesday 15 July 2026, and ask the most important question in football: is it actually coming home?What we covered#ICH: the birth of “It's Coming Home” energy and why this World Cup feels different.England's long road from the lows of Euro 2008, Steve McClaren's brolly, Iceland, and the underachieving golden generation.Why the modern England setup has changed: St George's Park, elite player development, the under-21 pipeline, and a squad that actually seems to like each other.Gareth Southgate's legacy: restoring pride and culture, even if tactical caution may have cost England against Italy, Croatia and Spain.Thomas Tuchel's England: more intensity, better defensive structure, set pieces, positive substitutions, and a clearer tactical plan.England's tournament so far: not always dazzling, but resilient, adaptable and capable of raising the level when the opposition demands it.Hydration breaks: cynical advert break, useful tactical reset, and Dan's preferred toilet window.England's attacking identity: direct, vertical, fast and built around Kane's movement, Bellingham's late arrivals, and wide players who can stretch tired full-backs.The “starters and finishers” idea: Madueke as chaos engine, Saka as late-game punishment.Argentina's threat: shithousery, tempo control, physicality, Romero, and the small matter of Lionel Messi.Cris's theory that England win if they keep the tempo high and make Argentina run.Predictions: Cris 3–0 England, Reegs 3–2 England, Sidey/Dan closer to 1–0 or 2–1, possibly after extra time.Sidey's BetBuilder: Gordon to score, Romero booked, England to go through.Key moments / quotesDan opens with the unavoidable: “It's coming home.”Sidey describes it as “a change to regular programming” because the World Cup has taken over.The group revisits the old England problem: club rivalries, players sitting at separate tables, and a golden generation that never really became a team.Cris backs the development pathway argument, noting how promoting from within helped bypass old rivalries.Dan gives Southgate credit for putting pride back into the shirt, even if he was not always convinced by him as a manager.Reegs frames Tuchel's England as reflecting “some of the best things about English football”: intensity, defensive security and set pieces.Cris says England are not Spain, France or Brazil in terms of central artistry — they are more direct, more vertical, more “crash bang wallop”.The group agrees Messi is still the great unknown: maybe the old days are gone, but nobody wants to be the team that finds out they are not.Sidey's gambling-adjacent closing thought: Gordon goal, Romero yellow, England through.VerdictConfidence is high, but nobody is fully relaxed because England are England and Argentina are Argentina. The dads are backing England to go through, but with varying degrees of emotional self-protection.You can now text us anonymously to leave feedback, suggest future content or simply hurl abuse at us. We'll read out any texts we receive on the show. Click here to try it out!We love to hear from our listeners! By which I mean we tolerate it. If it hasn't been completely destroyed yet you can usually find us on twitter @dads_film, on Facebook Bad Dads Film Review, on email at baddadsjsy@gmail.com or on our website baddadsfilm.com. Until next time, we remain... Bad Dads

St Georges School - Callum's Dad

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St Georges School - Dillon the beatles Take2

St Georges School - Jack Phineas And Ferb

Join The Revd Canon Dr Alison Joyce, Rector of St Bride's, and St Bride's Choir for this week's reflection in words and music. The English composer William Henry Harris was organist at St George's Chapel, Windsor for over thirty years and was appointed Knight Commander of the Royal Victorian Order for his service. Whilst there, he wrote two orchestral works which were premiered at The Proms and conducted at two coronations. However, he is best-known for his choral music and this week's reflection opens with the anthem "Behold, the tabernacle of God" which was written for the opening of the Royal School of Church Music at Addington Palace, Croydon in 1954. This week's reading is the famous and much-loved parable of the sower from St Matthew's Gospel. Alison reflects that the parable is neither about the sower or indeed the seed but about the soil. We close with the hymn "Come down, O Love Divine" by the 15th century Jesuit poet Bianco da Siena sung to the tune Down Ampney, which was the birth place of its composer, Ralph Vaughan Williams. Information about our weekly Sunday services in St Bride's of Choral Eucharist at 11am (www.stbrides.com/worship-music/wo…horal-eucharist/) and Choral Evensong at 5:30pm (www.stbrides.com/worship-music/wo…choral-evensong/) can be found on the website. Find out what's happening at St Bride's at www.stbrides.com/whats-on If you enjoy listening, please leave a comment below or subscribe to our channel. It is great to get your feedback. SUPPORT ST BRIDE'S ================== We are hugely grateful for people's generosity which we wholly rely on to continue our work, maintain our wonderful architectural heritage and support world-class music-making. People are often surprised to learn that St Bride's receives no external funding. If you would like to make a donation, you can do so at www.justgiving.com/stbrideschurchfleetstreet

It's been another busy week in S6 as the squad continues to take shape ahead of the new League One campaign.We look at the departures of Svante Ingelsson and Olaf Kobacki, the arrival of highly-rated Aston Villa defender Sil Swinkels, and the growing speculation surrounding Pierce Charles' reported move to Manchester City. There's also plenty to discuss on the rumoured arrivals front, with Harry Gray seemingly on his way from Leeds United and fresh reports linking the Owls with a permanent move for Louie Barry.Elsewhere, Barry Bannan has sent the fanbase into meltdown after appearing in training gear at St George's Park, while Joe Crann suggests both Bannan and Harry Gray deals are nearing completion.Off the pitch, we discuss Sheffield Wednesday's return to Umbro, the changes taking place at the Megastore, the removal of the old club crest from the South Stand, and what it all says about the club's new direction. We also take a look at the latest fixture changes that have left some supporters less than impressed.As always, we'll be giving our thoughts on the biggest talking points from another eventful week in the world of Sheffield Wednesday. Hosted on Acast. See acast.com/privacy for more information.

St Georges School - Kirsten Canada Part8

St Georges School - Kirsten Canada Part9

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St Georges School - Kirsten Canada Part6

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Southold Town historian, Amy Folk, and Darren St. George of Southold Historical Museum join Heart of The East End Gianna Volpe on WLIW-FM ahead of Folks' July 10 lecture, “Run-up to the Revolution” and the July 11 “Living History Encampment” event celebrating the country's 250th birthday on SHM's Maple Lane complex.Listen to the playlist on Apple MusicWatch the interview on WLIW-FM YouTube

St Georges School - Kirsten Canada p2

St Georges School - Jack's Smash Bros Ultimate

St Georges School - Callum prom

St Georges School - Kirsten Canada p1

St George Mining Ltd executive chairman John Prineas talked with Proactive about the company's latest progress at the 100%-owned Araxá Rare Earths and Niobium Project in Minas Gerais, Brazil, following a A$60 million capital raise and the release of its thickest mineralised intercept to date. Prineas said the funding was raised to top up cash reserves and accelerate development workstreams, with Hancock Prospecting contributing a further A$20 million and increasing its stake in St George Mining Ltd from 6% to 10%. He described the investment as “quite a strong validation” of the company's potential, noting Hancock's exposure to major rare earths producers outside China. The interview also covered the latest drilling result from the main deposit, where St George Mining Ltd reported 199.5 metres of high-grade mineralisation continuous from surface. Prineas said this was “a real point of difference” for the deposit, highlighting that the mineralisation starts at surface and continues down to around 200 metres. Prineas said St George is now moving toward development studies, supported by strong metallurgical test results and the appointment of Worley as feasibility technical manager. He said investors could expect further news flow over the next six months, including a scoping study, final metallurgical results and a potential final investment decision within 12 to 18 months. Visit Proactive's YouTube channel for more videos, and don't forget to like this video, subscribe to the channel and enable notifications for future content. #StGeorgeMining #SGQ #SGQMF #AraxáProject #RareEarths #Niobium #CriticalMinerals #BrazilMining #MiningNews #ASXStocks #OTCStocks #HancockProspecting #MineralExploration #InvestorNews #ProactiveInvestors

On this episode of Bad Dads Film Review, the team reviews This Is England (2006), Shane Meadows' raw, semi-autobiographical coming-of-age drama starring Thomas Turgoose, Stephen Graham, Vicky McClure, Joe Gilgun, Andrew Shim, Rosamund Hanson, and Jack O'Connell.In this episodeRecording outside the man cave in brutal heat, with England playing later and possible background birdsReturning to Shane Meadows after the dads' love for Dead Man's ShoesMeadows writing from lived experience and Shaun Field as a loose version of the young Shane MeadowsThe film's 1983 setting: Falklands aftermath, Thatcher-era mood, working-class Midlands anonymity, and immaculate period detailShaun's grief over his father's death and the brutal school bullying around his clothesThe infamous Mini joke, the playground fight, and Reegs' detour into the real-world Mini passenger recordWoody's gang as surrogate family: underpass tea, derelict-house “hunting”, haircuts, boots, braces, and the gifted Ben ShermanSkinhead culture before the racist takeover: ska, soul, punk, clothes, belonging, and styleSmell, the shed snog, New Romantic fashion, and the very awkward age-gap discussionCombo's entrance from prison and the immediate tonal shift from funny coming-of-age story to something threateningStephen Graham's performance as Combo: vulnerable, pathetic, charismatic, manipulative, racist, and terrifyingCombo gaslighting Woody, exploiting Shaun's Falklands grief, and splitting the gangThe National Front meeting: respectable presentation, simple blame politics, Frank Harper's speaker, and Gadget's “NASHNIL” spellingShaun's corruption under Combo: racist intimidation, the corner-shop robbery, and the stolen language of national prideLol rejecting Combo and the emotional humiliation that turns outward into violenceMilky and Combo bonding over music and roots before Combo's jealousy eruptsThe brutal beating of Milky, Shaun being forced to watch, and Combo's immediate collapse into remorseShaun throwing the St George's flag into the sea as a rejection of the racist version of EnglandThe continuing relevance of the film's politics from 1983 to 2006 to nowStrong recommendations for the follow-up series: This Is England '86, '88, and '90Bad Dads consensusSidey: Strong recommend — sees it as at least a 9/10 and reads the final flag moment as Shaun rejecting the National Front's corrupted version of England.Pete: Strong recommend — praises the film's lived-in authenticity, performances, and the follow-up series; still holds Dead Man's Shoes as a 10/10 comparison point.Reegs: Strongly positive — highlights the bleakness, the current relevance of the racist rhetoric, and Stephen Graham's frighteningly layered work.Cris: Engaged with the period detail, humour, and discomfort of the film's tonal shift, particularly once Combo arrives.Final takeThis Is England begins as a warm, funny, scruffy story about a lonely boy finding friends, then slowly reveals how easily grief and poverty can be weaponised by people offering simple enemies and ugly certainty. It is beautifully observed, brilliantly acted, deeply uncomfortable, and still horribly relevant.You can now text us anonymously to leave feedback, suggest future content or simply hurl abuse at us. We'll read out any texts we receive on the show. Click here to try it out!We love to hear from our listeners! By which I mean we tolerate it. If it hasn't been completely destroyed yet you can usually find us on twitter @dads_film, on Facebook Bad Dads Film Review, on email at baddadsjsy@gmail.com or on our website baddadsfilm.com. Until next time, we remain... Bad Dads

A daily low dose of aspirin could significantly reduce the risk of bowel cancer in people with Lynch syndrome, an inherited condition that increases the likelihood of developing certain cancers.   In this episode, we explore the findings from the landmark CaPP3 trial, hear from a participant living with Lynch syndrome, and discuss how genomics could help shift healthcare from treatment to prevention.  Our host, Sharon Jones is joined by:  Dr Katie Snape, Principal Clinician for Population Health at Genomics England  Professor Sir John Burn, Professor of Clinical Genetics at Newcastle University  Drew Hyde, participant in the Cancer Prevention Programme (CaPP3)  Links:  Listen to: How can genomics help us understand cancer?  "I think knowing is always a good thing. And obviously, I wish I'd known earlier, and then, I could have taken more measures earlier on. So I think knowledge is definitely a good thing. And it would be great if more people could be tested or could find out if they were carriers at an early age, I think."  You can download the transcript or read it below. [00:00:00] Sharon: Welcome to Behind the Genes. In today's episode, we'll explore the research which shows how a low dose of aspirin can halve the risk of bowel cancer in people with Lynch syndrome. We'll hear about the real-life impact of living with the condition, and look at how genomics can help shape a more preventative approach to care in the future. [00:00:20] I'm Sharon Jones, and to help us unpack all of that, I'm joined by our guests, Dr. Katie Snape, principal clinician for population health at Genomics England; Sir John Burn, professor of clinical genetics at Newcastle University; and Drew Hyde, a participant in the Cancer Prevention Programme, which is also known as the CaPP3 trial. [00:00:42] So to start with the basics, Katie, can you walk us through what cancer is in simple terms? [00:00:50] Katie: Sure, Sharon. So, our body is made up of cells. Those are the building blocks that, that make us as humans and other creatures and plants. And our cells need to keep dividing throughout our lifetime as our bodies are growing and working normally. [00:01:06] And so we need to have processes in place in our body where our cells can divide, but then also stop dividing when we don't need them to carry on dividing. What happens in a cancer cell is basically that cell becomes abnormal, and it doesn't follow the normal checks and balances and rules of cell division. [00:01:23] So it starts to divide and grow uncontrollably, and it can start to invade other tissues and obviously, that can cause serious consequences. [00:01:33] Sharon: We'll hear a lot more from Dr. Katie Snape in this episode. But before we move on, I just wanted to flag that there was an episode of our Genomics 101 explainer series with Katie dedicated to helping us get to grips with how genomics can help us understand and diagnose cancer. [00:01:47] Do go and check that out. We'll put a link to that in the episode description. [00:01:54] So the World Health Organization estimates between 30 to 50% of all cancers are preventable. So, Katie, when we talk about cancer being preventable, what does that actually mean? And what's an example of cancer prevention that people might already know? [00:02:11] Katie: Yeah. So some cancers are due to chance or just mistakes happening as our cells copy. [00:02:19] Other cancers are because there has been damage to the genetic information within the cell that can be caused by certain things that can cause damage to DNA. So for example, a sort of obvious answer would be skin cancer. Skin cancers can be caused by sunlight, the, the UV light in the sun, and particularly if we burn our skin or, or get sun damage to our skin, increases the chance of us developing a skin cancer. [00:02:44] So you can think of lots of other examples such as cigarette smoking and lung cancer, and so we know that there are a number of different risk factors that increase the chance of our cells developing damage and becoming abnormal cells and growing uncontrollably. So when we talk about prevention, we might think, well, could we reduce some of those risk factors and therefore reduce the chance of those cells getting damaged and becoming cancer cells? [00:03:10] So I gave the example of skin cancer. We might put sun cream on if we're going out in the midday sun, for example. That reduces the damage of the UV light onto our skin cells. Or we might help people to go into a smoking prevention programme or, you know, other risk factors, such as we know that being very overweight can increase the chance of cancer. [00:03:31] We might help people get into more exercise regimes or improve people's diets. So those are the sorts of things that we might do sort of for environmental risk factors. But we also know, particularly in this context, that sometimes people are born, they carry genetic changes within their cells that they're born with, that are inherited, that run through families, and those can also increase the chance of some cancers developing. [00:03:56] And for those people at higher genetic risk, then we might look to other ways that we might reduce that risk. We can't change the genetic changes in their cells, but we might be able to put things in place to reduce the risk for those individuals, and that might be medication, it might be surgery, or there could be other things that we might be able to offer. [00:04:15] Sharon: Yeah, and with that in mind, is there anything more, you know, that you can share about some of those risk factors that someone is more likely to develop cancer? [00:04:25] Katie: Yeah. So actually, the, the biggest risk factor for developing cancer is age. The older we get, the more times our cells have divided, the more chance there is of a copying mistake that, that, that can cause that cell to become abnormal and start growing uncontrollably. [00:04:41] And that's why cancer becomes more common the older we get. We obviously can't change our aging process. Then, as I've said, sometimes we're born with certain specific inherited factors that increase the risk. That might be one big high-risk genetic factor, such as having a cancer gene that's important for, for that process of cell division that isn't working properly. [00:05:04] Or it could be that we have multiple lower genetic risk factors that can kind of add up together to increase the risk. And those often interplay with some of those environmental factors that we've talked about, like smoking, for example, or weight, or alcohol or other things like that. So most cancers are due to aging, and then there's a sort of interplay of genetic factors, but environmental factors as well. [00:05:30] Sharon: That's really interesting to understand. And the focus of this podcast is sort of looking at kind of Lynch syndrome and what findings have come out around aspirin and having a low dose of aspirin. So I want to kind of explore what Lynch syndrome is and, and then bring in Drew to talk about his experience of having Lynch syndrome and how he got involved in the trials themselves. [00:05:49] So from what I understand, Lynch syndrome is a genetic condition that can make some people more likely to have the chances of developing into bowel cancer. And Drew, this is your opportunity to sort of talk about what that's been like living with Lynch syndrome. And, you know, I'd like to understand more about your story and how it came about that you discovered that you had Lynch syndrome, and to share with our listeners your journey. [00:06:13] Drew: Yep. So in my case, I discovered I had the colon cancer before I discovered I was a Lynch syndrome carrier Basically, at the age of 50, I noticed some change in my health. You know, I was becoming a little bit more tired. My bowel movements had changed or whatever. So, I went to the GP and the GP basically said, "Well, you're probably too young for cancer, so let's look at other alternatives." [00:06:37] And I had blood tests and I had low iron, so I was on iron tablets for three months and whatever. Then eventually I went back and finally the GP said, "Well, let's try a colonoscopy." And the colonoscopy revealed that I did actually have colon cancer. And then very quickly I had surgery and, uh, then following that, I kind of asked the question, "Well, why me?" [00:06:59] You know, I'm only 50, 51. Yeah. You know, why me? [00:07:02] Drew: And basically, I was told, "Well, it's probably genetics." And then I was referred to, you know, St George's and Katie and I had the test and discovered that I was actually a Lynch syndrome carrier, and that's why, you know, I'd got the colon cancer at the age of 50, so. [00:07:17] Sharon: I mean, that's quite a journey. I mean, how did you feel when you're already on one pathway and then having to kind of find out more, you know, what was your experiences? What was the impact on your life? How did you, how did you feel? [00:07:27] Drew: I think I was lucky in that I had a very good surgeon. I had surgery very quickly, so that was the first hurdle. [00:07:32] Then I had to go on to chemotherapy, and the chemotherapy obviously is far worse than any surgery or anything else that comes before or after. But having got through that, then I went through the St George's onto the Lynch syndrome system. So, the most important thing then really was to basically identify what that meant for me, but also because it was an inherited characteristic, what it meant for my family. [00:07:57] One thing that was interesting, and I say, you know, the, the GP was saying, "Well, you're too young to have cancer," is that there wasn't any history of cancer in my family, you know, looking at older relatives. So, you know, to be fair to the GP, that wasn't an obvious marker. So basically, yeah, it was let's, you know, find out what it means now going forward. [00:08:21] Sharon: So, can you just take us back to when you were diagnosed with Lynch syndrome? What sort of guidance were you given at the time about managing your cancer risk? [00:08:30] Drew: Well, following the surgery, I was given various statistics which were fairly grim on what your percentage survival rate were in three years, five years, 10 years based on the surgery, whatever. [00:08:39] And that was kind of a bit harrowing. But, you know, assuming I'd get through five years, I felt it was, my chances were quite good. As for myself living with, living with Lynch syndrome, that, you know, I was aware that having had the colon cancer, I then had increased risk of other cancers. So since then, I've been on a screening programme, and I have colonoscopies or gastroscopies every year or two years. [00:09:04] So that's been very good. So, I believe now that if any other cancers were to appear, I would probably know very early on because they would be detected through a screening process before they got to a point where they would be, you know, maybe too difficult to resolve, so. So that's-- I think the screening programme, has been very, very good. [00:09:23] The main issue for me was what it meant for my family, being a genetic thing. So very quickly, my children, who were teenagers at the time, were both tested, and they went through some counselling with Katie beforehand, you know, about what it would mean for them to get a positive or negative result. [00:09:42] Unfortunately, my daughter was tested as negative, but my son was tested as positive, so he's now on the same cancer screening programme, and has colonoscopies every two years. So yeah. The mystery really, though, is where I inherited it from because my father died when I was very young. My mother was in a care home at the time, and I wanted to get her tested. [00:10:07] And at the time, her GP wouldn't test her on the basis that she was unable to give consent. But fortunately, I had power of attorney, and we could persuade him to do the test. But she tested negative. So I'm assuming I inherited it from my father's side. But most of my grandparents on that side of the family lived into their nineties without any apparent cancers. [00:10:32] So it's still a bit of a mystery how I inherited it, but what was important for me was to know which side of the family I'd inherited it from because obviously with cousins and whatever on different sides of the family, I wanted to be able to tell them what the situation was. My brother also tested negative, which was a positive. [00:10:54] So at the moment, it's just my son and I that have the defective gene. [00:10:59] Sharon: I'm sorry to hear that about your son, but does it- [00:11:01] Drew: Well, well, I mean, he, you know, he has to go through a colonoscopy every couple of years, which, you know, obviously is not a pleasant experience. But at least he knows that, you know, the first sign of any problem, the medics will be aware of it, and he'll be able to react. [00:11:16] Sharon: Has it changed your outlook on life, having this window in possibly knowing stuff or not knowing stuff? How has that affected you and, and your son as well? [00:11:25] Drew: I think knowing is always a good thing. And obviously, I wish I'd known earlier, and then, I could have taken more measures earlier on. So, I think knowledge is definitely a good thing. And it would be great if more people could be tested or could find out if they were carriers at an early age, I think. [00:11:42] Sharon: Yeah. That is really important. And moving into about the trial more broadly, scientists have known that there's been a link between cancer and aspirin for some time, with fewer cancers observed in people who take aspirin. So coming to you, John, could you share a bit more about the history of inherited cancer research and how the focus of Lynch Syndrome came about? [00:12:02] Because this isn't new, is it? [00:12:06] John: No, absolutely, Sharon. And in fact, this story, my story in this space begins 40 years ago when I was one of the geneticists who set out to try and find the genes that we've just been talking about. At that time, the group of patients who were the most obvious to begin with were young people with a condition called familial adenomatous polyposis, or FAP for short. [00:12:26] And they'd get thousands of polyps in their bowel, and the only way to treat that was to actually remove the whole bowel when they reached adulthood, which is a fairly extreme intervention. And I was running, I was setting up a registry. We were trying to find the gene at that time, and we'd just found it, in fact, but we also were trying to find all the families. [00:12:44] And I'd taken over responsibility for all the genetic services in the north of England, in the North East and Cumbria. And we'd, I'd started identifying families with FAP, and we went to visit one of those families, and this was the kind of light bulb moment for me because I walked into the room and mum had had her colon removed, and her son, Jonathan, had just had his first colonoscopy at the age of 12, and it was clear. [00:13:07] And I was about to give them the good news, but as I walked in, I noticed that he had little bumps on his forehead called osteomas, little bony bumps. His mother had them just the same, and it was one of the features of this condition. So I knew he had the gene even though he hadn't yet got the polyps. [00:13:21] Sharon: Wow. [00:13:22] John: And it made me think, wouldn't it be nice if we could do something to prevent these things happening rather than just waiting for an operation? And as it happened at the time, I was leading the English end of a big study, which you'll probably be aware of, which we're, we're, we were doing the vitamin study on women with spina bifida babies, and we were just about to identify folic acid as a way of preventing spina bifida in pregnant women. [00:13:45] So I had these two thoughts in my head. Maybe we could set up a trial like this folic acid trial, and then one of my friends in Edinburgh said, 'Have you seen this paper from Melbourne?' Gabriel Kuhn had just done a big study looking at people with colon cancer. It seemed that people who took a lot of aspirin didn't seem to get as much bowel cancer in Melbourne as those who didn't. So that was the design set up. [00:14:08] We were applying to Europe for a concerted action, so we had to think of an acronym that began with CA. So I, I came up with Concerted Action Polyp Prevention. But then in 1993, just as we started that trial, we were involved in finding the first of the genes for Lynch syndrome. We had a big family in Northumberland where there were lots of people like Drew's family, and there were three generations of cancer in the family. [00:14:31] So CaPP2 was immediately born in my head. In 1999, we had our first recruit, and we recruited until 2005. We found, in total, 1,000 people in 16 countries to join in, and we gave them two aspirins a day or two dummy tablets. Two aspirins is quite a big dose, but back in my day when I was a junior doctor, we used to give many more tablets of aspirin to people with arthritis. [00:14:57] So two tablets wasn't such a big deal. Nowadays, it's seen as a very high dose. And it worked. Basically, to cut to the chase, when we looked in 2010, the people who were getting the aspirin were getting less bowel cancers. In fact, it was a 50% reduction. So the people who took two aspirins had half as many bowel cancers and fewer cancers of other types as well. [00:15:19] We realised, although, at this point, immediately we saw that it was working, we knew we'd need to do another trial to see whether a smaller dose of aspirin would be just as effective. So CaPP3 began, and the great news is that what we'll be reporting in the journals in the next few days when it gets published, is that the people who were taking  CaPP3 aspirin in any dose were tracking exactly the same as the 600-milligram group in CaPP2. [00:15:46] So we're pretty sure that it works. We're pretty sure that the small dose is just as good. And the great news was that we had fewer side effects in that group. And so in fact, no one had to go to hospital for a transfusion or anything, you know, like that. Whereas in the 600-milligram group, we had a few people who needed treatment because, as you know, and everyone knows, if you take aspirin, there's a higher chance of having an ulcer that causes a bleed. [00:16:10] And that was always the anxiety. But people like Drew were courageous enough to take the chance because they knew we needed to know the answer to this. And of course, when you compare it to the risk of getting cancer, taking an aspirin is a relatively small risk. [00:16:26] Sharon: So, what were your kind of considerations when you were designing the trial, having that knowledge? [00:16:32] John: Well, the first thing is it has to be fully informed consent, which means that you have to explain to people what that risk is. The important thing about aspirin is that doctors have a much worse opinion of it than it deserves because if you work in a hospital, you'll often see people coming in who've had a bleed. [00:16:48] It's not always caused by the aspirin. The thing is, if you're coming with a bleed and you're on aspirin, everyone blames the aspirin. Right. About half of them would've happened anyway. In fact, the, the irritation of the stomach is much more of a problem in older people So in fact, the average age of the people in CaPP2 and CaPP3 was about 45, 46 when they started. [00:17:08] Drew was a little bit older, but, but people in that sort of middle age group are much, much less likely to get into trouble than people in their 70s and 80s. And it's people also who've had a history of ulcers that have a bigger problem. We also knew that if you had a stomach infection called H. Pylori, which is itself a risk factor for cancer, and about one in six people carry that bug, and we knew that if we fixed that with antibiotics, that would significantly reduce the risk of bleeding as well. [00:17:37] So it was a manageable risk. It was something we could share with people. They knew they were taking a bit of a chance. But actually a good way of putting it in terms of the risk, for people in middle age, the risk of a low dose of aspirin is about the same as the risk of having a colonoscopy, which is very small, but it isn't completely without risk. [00:17:56] Sharon: Yeah, and Drew, kind of like hearing this sort of incredible, like, backstory about how we've got to these trials and where we are today What was your experience like as a kind of participant of this trial? [00:18:08] Drew: I understood I was going to be on 100, 300, or 600, but wouldn't know for at least three years, or was it five years? I can't remember. [00:18:15] And then sometime later in the post we got these packs, and it was ... I remember at the time thinking it was like a rather dull advent calendar - ... in that you'd have the days of the week- ... with the little, with the little windows, and you'd, you'd pop the tablets out three times a day and take them. [00:18:31] So I did that. I think, you know, I, I don't think I ever missed a day or whatever. Initially, I thought I must be on a really low dose, because I didn't actually notice any side effects. You know, I remember saying to my wife, I said, "Oh, I think I must be on the lowest dose, because I don't see any side effects." [00:18:46] It was a surprise years later when I was told actually I'd been taking 600, so. [00:18:51] Sharon: Wow. [00:18:52] Drew: It was quite an easy experience really. [00:18:54] John: We had a lot of problems. We had to pack the aspirin in six-month packs, because it was very expensive to pack this stuff up. It cost... We got the aspirin free from the Bayer company, but it cost us more than a million pounds to actually put it in, in the packs to satisfy the regulations. [00:19:10] Uh, and a lot of people complained that the packs were a bit big and awkward, but that was just, you know, a constraint. But it was not that big a deal once people got into it. But we did get a lot of complaints about the size of the packets, which we couldn't do anything about that. [00:19:24] Drew: They came regularly through the post, and, you know, so every three months or whatever I got another supply, and I just carried on taking them. [00:19:30] Yeah, so. [00:19:31] Sharon: What was going through your mind when you were kind of waiting for this potential outcome, Drew? Because you, like you say, it was, you know, it was a long time taking part. What was... Especially as you were opening your, you know, your package a day, knowing exactly what you were going to get. [00:19:44] Drew: Well, I, I kind of knew it would be a long-term thing. [00:19:47] I think I was committed for five years initially. But I carried on taking the aspirin for another probably five years after that. So yeah, I was just sort of happy to take the aspirin and then sort of wait to see what the results would be. As I say, that I didn't really notice any side effects, so I wasn't really worried that it was having any detrimental effect on me. [00:20:09] So I was curious to see what the, what the results would be. [00:20:12] Sharon: Yeah. John, the trial has provided like the evidence that, you know, low-dose aspirin can prevent bowel cancer. But are there any challenges that still exist with translating this research into clinic and ultimately patient care? [00:20:26] John: Well, yes, and I'm going to hand back to Katie, who's actually leading the charge on, on getting it into practice as well. [00:20:32] But just to say that I, I'm actually now literally on my other computer finalising my bid to go back to Cancer Research UK because we want to go for three more years. Wow. We said that we would follow people for 10 years after they'd finished their ... or after they'd started, so, you know, for at least 10 years. [00:20:50] So the last person to join didn't finish until 2024, so we won't get to that person. It's Robin and one of my patients. We won't get to Robin's 10-year anniversary until 2029. Oh, yeah. By which time, obviously, Drew will be even further on. But that will give us at least 10 years of follow-up because we know that there is this delayed effect, and that was seen right back at the beginning when people looked, for example, the nurses study in America, where they followed 86,000 nurses and just asked them if they took aspirin. [00:21:18] And nothing happened for 10 years, but those who were taking aspirin for more than 10 years saw a benefit. So in the general population, it probably takes that long to kick in. And so we need to keep going for just a while longer. It's not as expensive now because we're not giving people aspirin anymore. [00:21:33] Sharon: Yeah. [00:21:34] John: But one of the reasons we g- we made Drew's dose blind was because we wanted to know what the side effects would be when you didn't know how much you were getting There's a danger if you're getting a higher dose, you're more likely to complain. And actually, it did work out that the people on the lowest dose had the fewest side effects, even slight side effects. [00:21:51] The only thing we can't escape from is if you're taking aspirin, you get bruising more easily because it blocks the platelets, which are the little tiny blood cells which plug up little holes in your blood vessels when they leak. The good news is we now know that platelets turn out to be right, a major factor in triggering cancer. [00:22:09] And so the aspirin, by blocking the platelets, is actually reducing the risk of cancer, but also reducing the risk of cancer spreading in the body. So this is new research, and we've got another big research project in collaboration with a team in Cambridge who are, uh, pursuing this. Also, the other exciting news is that my other partner, Ruth Langley, is running a big trial of people with cancer, and those who are given aspirin as part of their treatment have less likelihood of getting spreading cancer later on. [00:22:39] So the aspirin is clearly doing something good at many levels in the system. Surprisingly, and we think it might be partly, partly because we used to have a lot of salicylate in our diet, which is what aspirin's made from. And we think that maybe we're putting back something that the body actually was used to having. [00:22:57] Yeah. But modern diets don't contain any, any salicylate because of the way we prepare our food. So it may well be that a little bit of aspirin's a good thing for everybody, but obviously, that's a choice that each person will have to make. [00:23:09] Sharon: Yeah. I mean, it's a real powerhouse of a, of a drug essentially, which you're finding out more about its benefits as, uh, as research goes on. [00:23:18] So Katie, can you just give us a bit of a broad overview of Genomics England's new adults program, which is kind of looking at this sort of area of work and, and what, how can it benefit people? [00:23:29] Katie: Yeah. Thank you, Sharon. So, the adults programme at Genomics England is being funded by government, and the government wrote about it in the 10-year NHS Health Plan, the Life Science Sector Plan to run a large-scale genomics population study. [00:23:44] So looking at how we can obtain genetic information from people in the population and look at more proactive and preventative healthcare, and can we generate evidence on where, how, and why the NHS should start applying genomics into kind of more population health measures. So, there's sort of two sides to this. [00:24:05] So the first is thinking about pharmacogenomics, which is basically about how genetic factors influence how we respond to drugs. So lots of people have had experiences of having side effects from drugs, we've just been talking about that with aspirin, or for drugs not working so well for them. And we know that there are certain drugs that genetic factors can influence whether you should take the drug at all, or if you do, what dose you should take, whether it's going to work for you or not, whether you might be more likely to get side effects or adverse reactions. [00:24:34] So part of the programme's looking at that. And then the other half of the programme will be looking at sort of is, are the genetic factors relevant for sort of serious and high-risk conditions in the adult population? So we could take bowel cancer as an example of that, a common condition, breast cancer, you know, common cancers or cardiovascular disease. [00:24:58] We know there are certain genetic factors for some people that have significantly increased their chance of developing those serious adult onset conditions. Can we find those people in the population and then put measures in place to prevent that? So, you know, even just thinking about Drew's story, he didn't have a family history of cancer. [00:25:16] The first time that he knew he had Lynch syndrome, he'd already developed bowel cancer. And we know that many people that have Lynch syndrome or other high-risk cancer genes are unaware of their status in the population, and so, um, the idea of this program is to really look at, well, if we were to, to look for some of these very high-risk genes in the general population, could we then put measures in place to reduce the chance of them developing the serious condition as a consequence? [00:25:44] So instead of Drew presenting with his bowel cancer, we'd actually already picked it up, despite the fact he doesn't have a family history, and we'd offered him, let's say, aspirin if we'd known the information at the time, and we could maybe have prevented him from developing bowel cancer. [00:25:58] So it's really exploring looking at that a little bit more. [00:26:02] Where can we get genetic information in the population? Where might there be a really well-evidenced, like all the work John's done over 40 years, is really well-evidenced now. Yeah. Yeah. Where are there these opportunities for us to turn the dial on some of these common adult onset conditions? [00:26:20] Sharon: What other challenges do you think with getting this out there do you see? [00:26:25] Katie: Uh, I think there's, there's lots of challenges. I think it's a really com- ... complex programme of work. The first thing is that the risks might be different for people in a population than have a family history. So where I've worked for, for years, and John as well in, in clinical genetics, we've seen the highest risk people, the people with lots and lots of cancer in their family because they're the people that are presented to healthcare services. So we've worked out the risks based on that population. It will be really different when we move to the population setting. We'll find fewer people, and the risks might be lower because there might be other factors that are giving them a lower risk. But that's not to say the risk is zero. [00:27:05] It's probably still raised. So then what we need to do is we need to consider, okay, well, what can we do to intervene, taking into account this change of context from people that we found through clinical services to people that we see in the population. And aspirin is a great example of this. [00:27:22] So, you know, if we find that someone has a Lynch syndrome gene, then taking aspirin, unless there's a really good reason for them not to take aspirin, is almost certainly going to be low cost to the NHS and really significantly reduce the chance of them developing bowel cancer with a low risk profile. So where are those opportunities? [00:27:41] And that isn't clear cut, and that's why we need a large scale research programme that can try to help the NHS answer some of those questions, so it can decide how best to spend its money in, in the people that are most likely to benefit from it with the least amount of risk or harm to them. [00:27:58] Sharon: That makes sense. And, and so, you know, going to you, Drew, what are your kind of thoughts on some of the challenges that Katie's highlighted? And is there anything else that you think needs to be improved in better supporting people living with inherited risk of cancer in the future? [00:28:14] Drew: In the brief sort of 10, 15 years or whatever since I've been s- suffering, awareness has increased greatly. [00:28:21] I mean, for example, my GP now knows about Lynch syndrome, whereas I don't think she did when I was first diagnosed, and I think there is a little bit more awareness out there, but I still think it's a lot less than there would be for, say, for breast cancer. So for example, when a high-profile personality reveals they've got breast cancer, you often get information about inherited risks. [00:28:44] You don't seem to get that with colon cancer. You know, when it's announced that so-and-so has died or is whatever, you don't get that same, you know, it, it might be a genetic thing. I mean, when I was first told people that I had bowel cancer, the response I got usually was, "Oh, poor diet, was it?" [00:29:04] And I always felt a bit upset, that, you know, actually my diet was fairly healthy. And that was the assumption that people had. So I think anything that gets the message out there that there is a risk, an inherited risk, I'm not sure what the statistics are now, Katie, is it one in 400 people might be a Lynch syndrome carrier or something like that? [00:29:24] You know, it's relatively high for something that is, if you know in advance you're at risk, you can do something about it. But like me, you know, I waited until it was too late, because I didn't know, and then had to have the surgery, so anything that promotes the message that there is a risk. I know some people don't want to know about their genetic makeup. Obviously, that's a choice. But I think to give people, as many people as possible, the choice must be a good thing. [00:29:54] Sharon: Yeah, absolutely. And I think one thing I've noticed through this thread is the sort of theme of funding and what gets funding and the amount of time it takes to, to kind of get that funding. [00:30:05] Is there anything you wanted to add around the kind of funding model, around why some things get funded, you know, uh, more prominent, like Drew's point, obviously, talks about if someone high profile kind of comes forward and says XYZ, that gets the spotlight shone on it, and there might be research going that direction compared to s- to, to other cancers. [00:30:23] John: So maybe I could speak at that. So partly because of my experience, I've now been made chairman of the grant committee at Cancer Research UK for prevention and population research. And there is a real drive to push more resource into prevention for the obvious reasons. [00:30:39] Katie: Yeah. [00:30:39] John: And also, it's got to be remembered, it's very difficult for the drug companies to fund this because it takes such a long time that the drug's- Mm [00:30:46] out of its patent before they actually get to use it. So, it's very difficult from a business point of view to fund research into prevention. But they are keen to help us, uh, but we really need sort of central government and the charities to focus on prevention if it's going to make a difference. [00:31:02] And just on Drew's point on diet, I mean, diet is still important even if you have Lynch syndrome. In our CaPP2 trial, the people who were overweight were more than double the risk of cancer. So it's not like an either/or. If you've got a higher genetic risk and you have a bad diet, then that's, you know, is going to contribute. [00:31:21] But the other exciting thing is, of course, we now have medical ways of treating obesity in, in people. So, one of the interesting areas is whether we should be, in the same way as we are for other high-risk populations with overweight, we should be giving overweight people with Lynch syndrome, help to lose weight because that will also reduce their risk. [00:31:41] It's also worth just dropping in at the last moment here is that this is also a good news story in terms of treatment and further prevention. We now have a new class of drugs called immune checkpoint inhibitors, which specifically target the types of cancer that Drew had and are much more effective in curing them And also, we've just been given funding to do a project called LynchVax, which I'll be helping with, but it's led by David Church in Oxford. [00:32:05] And this is developing a vaccine against cancers in people with Lynch syndrome. The great news is it'll probably work alongside aspirin because we know the aspirin is enhancing the immune response. So the two together may make this a curable condition. [00:32:18] Sharon: That's actually incredible. I mean, that, it gives so much hope for people. [00:32:23] And I just wanted to find out if you had any more kind of reflections as we close, because we're going to come to the end of our podcast today. If there's anything more that you wanted to share, anything that has been missed, or anything that you want our listeners to know, and I think I'm gonna come to you, Drew, first, because you're the person who's had to sort of live through this and, and go through this journey along the way. [00:32:41] Drew: I think just basically, if you're not sure, get tested. Obviously, there are financial constraints. I'm sure that running a DNA test is quite an expensive business. But I think if you've got any history of bowel cancer in the family, you've got any concerns about your health, speak to a GP and see if you can get tested as quickly as possible. [00:33:00] And then, to get a better message out there that there are risks of inherited colon and other similar cancers, so. [00:33:11] Sharon: Yeah, so it's getting that, messaging out, um, for people to understand more and make those informed choices. And Katie? [00:33:18] Katie: I mean, I would say that the power of, of our, you know, NHS and our academia and, and our healthcare system has been collaboration. [00:33:26] Sharon: Yeah. [00:33:27] Katie: There's so many moving parts. There's commissioners, there's funding, there's the evidence, there's research, there's healthcare implementation. The UK's a really amazing place to work in genomic medicine, and I think that's partly because of the amazing collaborations that we have, and the way that we can translate research into healthcare as John's team have done with this amazing study. [00:33:48] So let's all keep working together, please. [00:33:52] Sharon: Absolutely. And John, it feels like this is your lifetime's work. [00:33:58] John: Well, I've become aspirin man, it wasn't intended. But Katie's done fantastic work in her role as chair of the Cancer Genetics Group in the UK, so we've now implemented a, [00:34:06] we're the first in the world to really make this an absolute directive to the GPs and all, to all doctors to say, "People with Lynch syndrome need to be offered aspirin." And so that's a great step forward. But we also need to get it into the British National Formulary, and I'm working with their team so that the GPs are empowered to do this. [00:34:24] It's actually part of their care package. But I would just say we've still got a long way to go. We've now got a national list of all the people with Lynch syndrome, like Drew, to make sure we offer them all a colonoscopy, but there are only 14,000 people after several years of really pushing. [00:34:40] Sharon: Right. [00:34:40] John: We think in the national population in all ages, it's about 1 in 300. That's a lot of people. That means there's about 150,000 people like Drew in the country, and we've only found 10% of them. So we can't just rely on family history for all the reasons Drew explained. You know, I mean, Drew's dad probably died of Lynch syndrome, but we don't know because we've lost that record. [00:35:02] So now we're checking every bowel cancer to see if it might be caused by Lynch, and that programme is now kicking in, and we're picking up a lot more gene carriers as a result of that. But there's still a long way to go to get co- get people aware of Lynch syndrome, to think of it when someone presents with a cancer, not just of the bowel, but in the womb, in the kidney, in other parts of the body. [00:35:23] It's not just the bowel, but that's the most important group. [00:35:26] Sharon: Yeah. [00:35:26] John: So there's still a long way to go. [00:35:28] Sharon: Where you've come to now is still an incredible achievement, even though we've still got a long way to go, and I don't think we should ever lose sight of that. So we're going to wrap it up there. Thank you to our guests, Katie Snape, Professor Sir John Burn, and Drew Hyde, for joining me today as we discuss cancer prevention. [00:35:48] If you'd like to hear more like this, please subscribe to Behind the Genes on your favourite podcast app, and thank you for listening. I've been your host, Sharon Jones, and Behind the Genes is produced by Deanna Barac, Florence Cornish, Sophie McLachlan, and Dave Howard at Bespoken Media.  

Jeremy Kyle unpacks the latest as Oxfordshire's bid to ban roadside Union and St George's flags has reignited arguments over patriotism, safety and council priorities. The High Court challenge comes during England's World Cup campaign, prompting Conservatives and Reform to accuse Liberal Democrats of overreach. Meanwhile, revelations that pro-migration campaigners coached refugees for Question Time have intensified scrutiny of BBC impartiality on immigration.Wake up with Talk Breakfast in full on YouTube, DAB+ radio, Samsung TV Plus or the Talk App on your TV from 6am every morning. Hosted on Acast. See acast.com/privacy for more information.

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The video uses the burial of Henry VIII in St. George's Chapel as a meditation on the universal realities of death—its humility, finality, and the eternal destinies it determines. It emphasizes that no amount of power, wealth, or fame can escape the dignity of death, which levels all people before God. Drawing from Scripture, it highlights Christ's authority over death and Hades, underscoring the critical choice between two eternal outcomes. The sermon then turns to the theme of legacy, challenging listeners to reflect on how they will be remembered and whether their lives reflect a faithful stewardship of God's grace. Ultimately, it calls for daily living in light of eternity, knowing that on the day of judgment, one's true self will be revealed before Christ.

The video uses the burial of Henry VIII in St. George's Chapel as a meditation on the universal realities of death—its humility, finality, and the eternal destinies it determines. It emphasizes that no amount of power, wealth, or fame can escape the dignity of death, which levels all people before God. Drawing from Scripture, it highlights Christ's authority over death and Hades, underscoring the critical choice between two eternal outcomes. The sermon then turns to the theme of legacy, challenging listeners to reflect on how they will be remembered and whether their lives reflect a faithful stewardship of God's grace. Ultimately, it calls for daily living in light of eternity, knowing that on the day of judgment, one's true self will be revealed before Christ.

It's been a disappointing season for the Red V to say the least, but signs are looking up after securing their first win of the season. The St George interim coach, Dean Young, joins Mark Levy, Mark Geyer, Darryl Brohman and Mark Riddell to discuss their recent victory, his intense training schedule, and why he's feeling positive about next season.See omnystudio.com/listener for privacy information.

This week, in St. George, Utah, when a woman's friend finds the woman's house empty, but with pools of blood on the carpet, and a bullet hole in the window, a massive search begins. It's a real mystery, with everyone wondering where the body could've been moved. A piece of a specific plant, stuck in the woman's tires, leads police to her body, and the horrible discovery of what happened to her, after she died. An unlikely suspect emerges, and he has an excuse that will make this case national news. He claims that the medicine Prozac made him a cold blooded killer... and worse!!   Along the way, we find out that dinosaurs are definitely extinct, that the 1980's was a good time to name your cat "Rambo", and that when you have 14 different drugs in your system, it's pretty difficult to blame one of them for your problems!!   New episodes, every Wednesday & Friday nights!! Check us out on VIDEO Wednesday and Friday evenings on Netflix! www.netflix.com/smalltownmurder Go to shutupandgivememurder.com for all things Small Town Murder, Crime In Sports & Your Stupid Opinions!   Follow us on... instagram.com/smalltownmurder facebook.com/smalltownpod   Also, check out James & Jimmie's other shows, Crime In Sports & Your Stupid Opinions on Apple Podcasts, Spotify, or wherever you listen to podcasts!!

On this episode of Distilling the West, Dan and Dave sit down with Dave Smith, Head Distiller and Co-Owner of St. George Spirits out of Alameda, California. This interview is an incredible conversation about how intention is behind everything that is done at St. George. Dave talks about how sense memories drive the development and production of their exceptionally made craft spirits at St George. Dave has some of the most descriptive storytelling we have heard on the show that will transport you, and we're here for it!Dave brings every story to life, from the people behind the spirits to the details of the distilling process. It was truly enjoyable to hear him share his experiences, his passion, and the deep and rich stories behind St. George Spirits.Throughout the episode, Dan and Dave taste through Pear Brandy, Valley Gin, and St. George American Single Malt Whiskey, Lot 25. Each pour leads to a deeper conversation about sense memories, complex yet intentional flavor, striving for perfection, and the unique approach that has made St. George Spirits such an important name in American craft distilling.Join us for this memorable episode with one of the best American craft spirit distilleries in the industry. Cheers to St. George!

Russell Myers and Jennifer Newton discuss the latest Royal news, including King Charles reflecting on his cancer journey at the opening of the Sir Robert Ogden Macmillan Cancer Centre this week. Prince William also paid a visit to St George's Park to meet Thomas Tuchel and the staff at the FA ahead of England's participation in the 2026 World Cup this summer. Learn more about your ad choices. Visit podcastchoices.com/adchoices

This book is a fucking delight.

It will be lights out for a top Hawkes Bay restaurant next week. But don't panic St George's restaurant is unplugging as part of World Environment Day. All non-essential electricity will be switched off; it will be candlelight all the way. But without an oven what's the plan for cooking the kai? St George's owner Frankie Godinho spoke to Lisa Owen.

It's YOUR time to #EdUp with Charles R. Modica, Chancellor, St. George's UniversityIn this episode, President Series #475, powered by ⁠⁠⁠Ellucian⁠⁠⁠, sponsored by EdUp Leadership, the ​HigherEd PodCon​ II happening July 16 & 17, & the 2026 AcOps Conference July 29-31 by CoursedogYOUR host is Dr. Joe SallustioHow does a self-appointed chancellor who founded a medical school in Grenada at 25 celebrate 50 years leading the same institution?Why did writing Harvard, Yale & Stanford for curriculum bulletins & inviting textbook authors as visiting professors build a world class faculty?What makes an idyllic island where the Jewish & Muslim Student Associations met together the night after 9/11 a model for international education?Listen in to #EdUpThank YOU so much for tuning in. Join us on the next episode for YOUR time to EdUp!Connect with YOUR EdUp Team - ⁠⁠⁠⁠⁠ ⁠⁠⁠⁠Elvin Freytes⁠⁠⁠⁠⁠⁠⁠⁠⁠ & ⁠⁠⁠⁠⁠⁠⁠⁠⁠ Dr. Joe Sallustio⁠⁠⁠⁠● Join YOUR EdUp community at The EdUp ExperienceWe make education YOUR business!P.S. Want to access to EdUp Leadership, the only intelligence platform built exclusively from presidential conversations in higher ed?

This Saturday, Louisiana voters will weigh in on whether to let the new city of St. George form its own school district. To do that, they have to amend the state's constitution.The Baton Rouge breakaway suburb has been trying to start its own school system for more than a decade. WRKF's Report for America corps member Alex Cox joins us with more.The Louisiana Association of Chamber of Commerce Executives and the Louisiana Policy Institute for Children have partnered to bring a recognition called “The Best Place for Working Parents” to Louisiana. The recognition acknowledges employers who self-assess to gauge how friendly their workplace is for workers with children. Taylor Henry, executive director of the Louisiana Association of Chamber of Commerce Executives, tells us more about improving working conditions for parents. Since the Make-A-Wish Organization was first founded, it's helped grant more than 12,000 wishes to children in Louisiana. In 2025, it granted 650 wishes across the Gulf Coast region, the highest total in the organization's history.May is a busy month for the Make-A-Wish Texas, Gulf Coast and Louisiana Chapter. After World Wish Month and World Wish Day, the organization has many local events hoping to raise money to support the mission. Wish Kid, Abron Fyre, his mother Misty Frye, and the organization's director of development, Tommy Fonseca, join us with more.—Today's episode of Louisiana Considered was hosted by Adam Vos. Our managing producer is Alana Schreiber. We get production support from Garrett Pittman and our assistant producer, Aubry Procell.You can listen to Louisiana Considered Monday through Friday at noon and 7 p.m. It's available on Spotify, the NPR App and wherever you get your podcasts. Louisiana Considered wants to hear from you!Please fill out our pitch line to let us know what kinds of story ideas you have for our show. And while you're at it, fill out our listener survey! We want to keep bringing you the kinds of conversations you'd like to listen to.Louisiana Considered is made possible with support from our listeners. Thank you!

I've got a free place to stay in St. George

Kae Tempest is widely regarded as one of Britain's greatest wordsmiths. In a career of ferocious creativity, he has received multiple prizes and critical recognition across the many forms he works in. Beginning as a lyricist and songwriter in his teens, Tempest threw himself fully into whichever discipline he could find work in; gigging as a poet, writing for the theatre or busking with his band. A decade later, this obsessive compulsion to push his writing as far and as hard as he could, secured him a record deal with UK independent label Big Dada and a poetry publishing contract with Picador. Tempest's work has always sought to pull the focus between the global or national concerns of a character, and the private, very intimate experiences of their lives; the minuscule and the mundane peering out from behind the incomprehensibly large and overpowering. Whether it's austerity, addiction, communal disassociation, the planet in crises, or the death of our prevailing myths, the bigger picture is always made up of tiny parts. We were joined by Tempest live on stage at St George's, Bristol as he discussed his much anticipated return to fiction. His first novel in a decade, Having Spent Life Seeking is the story of Rothko Taylor, who returns to their hometown of Edgecliff, seeking a place to belong after fifteen years in the wilderness. It weaves together themes that have shaped Tempest's work to date: family and forgiveness; redemption and atonement; desire and abandon; selfhood and community. Themes that are dealt with in this new novel, with a deeper resolve and a new clarity of intent. ---  If you'd like to become a Member and get access to all our full ad free conversations, plus all of our Members-only content, just visit intelligencesquared.com/membership to find out more. For £4.99 per month you'll also receive: - Full-length and ad-free Intelligence Squared episodes, wherever you get your podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series - 15% discount on livestreams and in-person tickets for all Intelligence Squared events  ...  Or Subscribe on Apple for £4.99: - Full-length and ad-free Intelligence Squared podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series … Already a subscriber? Thank you for supporting our mission to foster honest debate and compelling conversations! Visit intelligencesquared.com to explore all your benefits including ad-free podcasts, exclusive bonus content and early access. … Subscribe to our newsletter here to hear about our latest events, discounts and much more. https://www.intelligencesquared.com/newsletter-signup/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Kae Tempest is widely regarded as one of Britain's greatest wordsmiths. In a career of ferocious creativity, he has received multiple prizes and critical recognition across the many forms he works in. Beginning as a lyricist and songwriter in his teens, Tempest threw himself fully into whichever discipline he could find work in; gigging as a poet, writing for the theatre or busking with his band. A decade later, this obsessive compulsion to push his writing as far and as hard as he could, secured him a record deal with UK independent label Big Dada and a poetry publishing contract with Picador. Tempest's work has always sought to pull the focus between the global or national concerns of a character, and the private, very intimate experiences of their lives; the minuscule and the mundane peering out from behind the incomprehensibly large and overpowering. Whether it's austerity, addiction, communal disassociation, the planet in crises, or the death of our prevailing myths, the bigger picture is always made up of tiny parts. We were joined by Tempest live on stage at St George's, Bristol as he discussed his much anticipated return to fiction. His first novel in a decade, Having Spent Life Seeking is the story of Rothko Taylor, who returns to their hometown of Edgecliff, seeking a place to belong after fifteen years in the wilderness. It weaves together themes that have shaped Tempest's work to date: family and forgiveness; redemption and atonement; desire and abandon; selfhood and community. Themes that are dealt with in this new novel, with a deeper resolve and a new clarity of intent. --- This is the first instalment of a two-part episode. If you'd like to become a Member and get access to all our full ad free conversations, plus all of our Members-only content, just visit intelligencesquared.com/membership to find out more. For £4.99 per month you'll also receive: - Full-length and ad-free Intelligence Squared episodes, wherever you get your podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series - 15% discount on livestreams and in-person tickets for all Intelligence Squared events  ...  Or Subscribe on Apple for £4.99: - Full-length and ad-free Intelligence Squared podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series … Already a subscriber? Thank you for supporting our mission to foster honest debate and compelling conversations! Visit intelligencesquared.com to explore all your benefits including ad-free podcasts, exclusive bonus content and early access. … Subscribe to our newsletter here to hear about our latest events, discounts and much more. https://www.intelligencesquared.com/newsletter-signup/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Gideon Levy, Haaretz columnist, talks about the current state of violence and settlements in the West Bank.Photo: US ambassador to Israel Mike Huckabee (C) and the Palestinian mayor of the village of Taybeh, Suleiman Khourieh (C-L), tour the fifth-century Church of St George in the Palestinian Christian village of Taybeh, northeast of Ramallah in the occupied West Bank, on July 19, 2025. In the villages and communities around Taybeh, Palestinian authorities have reported that settlers had killed three people and damaged or destroyed multiple water sources in the past two weeks alone. The July 7 arson attack on the remains of the Church of Saint George, which date back to the 5th century, was the last straw for many villagers, who blame Israeli settlers for a spate of recent attacks. (Photo by JAAFAR ASHTIYEH / AFP via Getty Images)

"George, this truly great and glorious Martyr of Christ, was born of a father from Cappadocia and a mother from Palestine. Being a military tribune, or chiliarch (that is, a commander of a thousand troops), he was illustrious in battle and highly honored for his courage. When he learned that the Emperor Diocletian was preparing a persecution of the Christians, Saint George presented himself publicly before the Emperor and denounced him. When threats and promises could not move him from his steadfast confession, he was put to unheard-of tortures, which he endured with great bravery, overcoming them by his faith and love towards Christ. By the wondrous signs that took place in his contest, he guided many to the knowledge of the truth, including Queen Alexandra, wife of Diocletion, and was finally beheaded in 296 in Nicomedia." (Great Horologion) The Empress Alexandra, along with a pagan priest who confessed Christ due to George's witness, were executed together with the Great Martyr. St Alexandra is commemorated on April 21/May 4.   Neither the Great Horologion nor the Prologue, nor the Church's services to St George, mention the most popular story of St George, his slaying of a dragon. Though many icons of the Saint show him mounted on horseback, slaying a dragon with a spear, the story is thought by many to be legendary, and the dragon in the icon symbolic.

This week James tells you all about the history of St George, the Patron Saint of England.   Talking Codswallop can be found on ALL social media: @CodswallopPod and we are on YOUTUBE too!!! :)  NOW ALSO ON TIKTOK. Talking Codswallop is NOW part of the UNFILTERED Studios. Find out more about them here: unfpod.com & help support INDIE podcasts. 

He was born in Sykeon in Galatia in Asia Minor. (The Great Horologion says that he was born out of wedlock; the Prologue that his mother, Maria, was a rich widow; in either case, he was reared by his mother alone). At the age of ten, Theodore took up a life of strict asceticism, devoting himself to prayer, fasting and vigils. His mother planned for him to enter the military; but St George appeared to her in a dream, telling her that Theodore was to serve the King of Heaven rather than any earthly king. After this, Saint George appeared to Theodore many times, sometimes instructing him, sometimes saving him from danger. After a trip to the Holy Land, Theodore became a monk in Galatia — we should say "officially became a monk," since he had been living as a monk from the age of ten. Once he had taken monastic vows, Theodore redoubled his ascetical labors, which exceeded those of any other monk of his time: for his asceticism, he was sometimes called the "Iron-eater." Around 584 was ordained Bishop of Anastasiopolis in Galatia, much against his will. He served his flock faithfully for ten years, then begged to be relieved of his episcopal duties so that he might return to his beloved monastic life. Even during his lifetime, he was famed for his miracles and his authority to cast out demons. He departed this life in peace in 613.

Few people know that outside the United States, the most popular saint in the world is St. George! Why? Was the story of him slaying a dragon real? Why is he honored in Islam? Hear Fr. Chris Alar tell this incredible story of the saint you need to know more about, because the rest of the world does.