1978 studio album by Laura Nyro
POPULARITY
It's a week of surprises as we update our running list of the year's best music, with a mix of songs that refuse to be any one thing. Plus, singer Brandi Carlile drops a stunning, stadium-sized rock anthem.NPR Music editor Sheldon Pearce joins host Robin Hilton.Featured artists and songs:1. Brandi Carlile: “Church & State,” from ‘Returning to Myself'2. Hannah Frances: “The Space Between (feat. Daniel Rossen),” from ‘Nested in Tangles'3. Kelly Moran: “Don't Trust Mirrors,” from ‘Don't Trust Mirrors'4. Blood Orange: “The Last of England,” from ‘Essex Honey'5. Magdalena Bay: “Second Sleep” (single)Weekly reset: A family of bears rummage through a forest on an autumn afternoon.Enjoy the show? Share it with a friend and leave us a review on Apple, Spotify, or wherever you listen to podcasts. Questions, comments, suggestions or feedback of any kind always welcome: allsongs@npr.orgLearn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Lords: * Elena * Joël Topics: * The Luck Factor: * http://www.richardwiseman.com/resources/TheLuckFactor.pdf * Dual pilgrim certificate * The return of PicoSteveMo * https://itch.io/jam/picostevemo-3 * Every poem, by every human * https://www.tumblr.com/nextworldover/793694487879827456/animatedamerican-atamascolily Microtopics: * Packing cubes. * The Rolling Method. * Modular backpacks. * Camera people: a different type of people. * Nested zippered envelopes labeled one through five. * Why does your purse say "three" on it?? * Tool user opinions. * Getting ready for fiction to incorporate our new conception of what AI is. * Running experiments on people who self-identify as lucky or unlucky. * Gladstone Gander. * Paying your put-upon nephew a dime to accompany you on a trip to Zazu-Zazu. * Stan Connery's terrible taste in roles. * Natalie Portman's Tom Scott number. * Systems that are gamable but not trivially gamable. * Rick Rubin numbers vs. Sabbath Numbers. * The Kumano Kodo Trail's trail adjudicators ringing a bell and giving you a certificate to certify that you've walked their trail. * A terrible time of year to hike the Camino de Santiago. * Taking a wrong turn while hiking the Camino de Santiago and ending up on France. * All the school children running over to high five the pilgrims. * Feral Eucalyptus plantation. * Peeking into all the ancient mills. * Shrine tossing tricks. * Passing bones from chopstick to chopstick. * The three major sources of ritual pollution. * Getting sick of climbing the hill all the time so you write a poem explaining that the gods don't want the shrine to be at the top of the hill any more. * Harassment prevention for non-supervisors. * Printing and framing the certificate you got after taking the class on filling out your timecard. * The uncle so otherwise never contacts you sending you a happy birthday message on LinkedIn every year. * Endorsing your friend on LinkedIn for being a git. * Balloons in the sewer. * Sokoban mechanics that could apply Stephen King's It. * A tricycle kart racer set in the Overlook hotel. * NanoSteveMo. * The scruffy guy the hotel manager doesn't want around. * Singlehandedly supplying the fanbase for this Mo. * Hoarding Pico-8 cartridges on you desktop. * The Spore creature creator exporting your creature as a PNG. * A topic for another Topic Lords. * Concatenating a zip file to the end of a different file. * Here's this artifact. Please try it out. * Saving PNGs to Starlings. * Storing your Pico-8 game in a bird. * Shamir's Secret Sharing Scheme. * Pirating software on Usenet. * Catching 50 out of 100 birds to extract the Pico-8 game from them. * Realizing that it's a plums in a refrigerator thing and moving on. * Helping a stranger grieve using your well-honed crossword skills. * Approaching classical literature as a collection of in-jokes and wanting to be in on the joke. * A book with a serrated edge. * How to read a book vs. how to read a poem.
Digging into history. And a few eggshells. As we continue our 31 days of Odd News stories, we the podcast travel to Spain. Well, not actually, but we'll talk about people who did. And that's what really matters. Because they find some nested treasur. We'll also bring you a classic clip that may be more relevant now than it was in 2015. Let's dive into things a bit deeper, shall we? First up, we'll have a look at researchers in Spain who have gone to great lengths, and heights, to do some archeological research. But these investigators aren't chipping away at rocks or digging into sand while some guy wearing a fedora just looks on. No. Too bad, because that would be odd, too. These researchers are taking advantage of the traits of some winged creatures and their habits. You'll have to tune in to hear exactly what these feathered hoarders managed to get their beaks on! In addition as we continue to celebrate 20 years of comedy4cast, our so-called Platinum Anniversary of comedy4cast (PAC), we're taking you back to 2015 for a clip that you might call "The Land Before ChatGPT." How close did we come to foreseeing the future? You be the judge. (But not a real one. It takes so long to go through the process, you might forget what the episode was about.) Just listen and hear what we did and have fun with it. So, are you ready to hear a strange tale of nested treasure and revisit 2015? It's all waiting for you. Just play the episode! Don't forget, you can also support comedy4cast and get episodes before everyone else for as little as $2 a month. >> You can also support comedy4cast by becoming a patron on Patreon>> Or you can get Clinton a Dunkin' card or a cup of coffee via Ko-Fi>> Follow comedy4cast on BlueSky, Instagram, Facebook, MeWe, and Mastodon >> Give us a call via the Super Secret Phone Line (213) 290-4451>> Also check out Clinton's other podcast, The Topic is Trek>> Certain sounds effects heard on comedy4cast are courtesy of freeSFX and FreeSound.org Click here for a transcript of this episode.
On today's episode, I talk to musician Hannah Frances. Growing up just outside of Philly, Hannah was doing all kinds of creative work from a young age, from singing to poetry to composing. In 2018, she made her first album White Buffalo, and since then has recorded four other albums. Her fourth album Keeper of the Shepherd garnered a great deal of acclaim leading Fire Talk Records to reissue it earlier this year, as well as release her new album Nested in Tangles, which is out next week, and it is fantastic! This is the website for Beginnings, subscribe on Apple Podcasts, follow me on Twitter. Check out my free philosophy Substack where I write essays every couple months here and my old casiopop band's lost album here! And the comedy podcast I do with my wife Naomi Couples Therapy can be found here! Theme song by the fantastic Savoir Adore! Second theme by the brilliant Mike Pace! Closing theme by the delightful Gregory Brothers! Podcast art by the inimitable Beano Gee!
the UI at https://nothing.tech/products/phone-3 renders a list of "widgets". I would like each of these widgets to have their own loaders to maximise page speed, furthermore I'd be able to "deeplink" a user straight into a widget. But how do I do that when a route can only have one Outlet? Here's an example with Promise.all. Before: // routes/dashboard.tsx export async function loader() { const user = await fetch('/api/user').then(r => r.json()) const projects = await fetch(`/api/projects?userId=${user.id}`).then(r => r.json()) const notifications = await fetch(`/api/notifications?userId=${user.id}`).then(r => r.json()) return { user, projects, notifications } } After: export async function loader() { const userPromise = fetch('/api/user').then(r => r.json()) const projectsPromise = userPromise.then(user => fetch(`/api/projects?userId=${user.id}`).then(r => r.json()) ) const notificationsPromise = userPromise.then(user => fetch(`/api/notifications?userId=${user.id}`).then(r => r.json()) ) const [user, projects, notifications] = await Promise.all([ userPromise, projectsPromise, notificationsPromise, ]) return { user, projects, notifications } } Kent's notes: I forgot that defer is now unnecessary, simply return an object from your loader and any properties on that object that are promises will be sent along as deferred data automatically. Learn more from the links below. Full Stack Components Streaming with Suspense React Router and React Server Components: The Path Forward promiseHash from remix-utils How far can nested UI loaders go for UIs with list of components
Kia ora,Welcome to Monday's Economy Watch where we follow the economic events and trends that affect Aotearoa/New Zealand.I'm David Chaston and this is the international edition from Interest.co.nz.And today we lead with news there was an unexpected turn in the US tariff situation late last week.In a dramatic ruling, most of Trump's global tariffs were declared illegal by a US appeals court that found he exceeded his authority in imposing them. He will almost certainly appeal to his Supreme Court.Then, over the weekend we got the official Chinese PMIs for August and they extended the sluggish environment their manufacturing sector finds itself in. Despite the 90 'extension' before punitive tariffs kick in with the US, orders contracted for a fifth consecutive month. On the services side however, they maintained their small expansion in August, albeit marginally better.But early data suggests their housing slump is not ending, maybe even getting worse. Sale volumes in August are likely to be more than -17% lower than a year ago.Although it is a shortened week in the US, it ends with the August jobs data. Markets expect another weak result (just +78,000). You will recall the weak data last month saw Trump fire the agency head who compiled it. So there will be special attention this time on its believability under the BLS agency's deputy. Before that we will get lead-up jobs data, the ISM PMIs for the US.Canada will also release labour market data. The EU inflation data, and others will release GDP data for Q2-2025, including from Australia on Wednesday.At the end of last week, July data out in the US shows that disposable personal income was up +2.0% from a year ago, personal consumption expenditure was up +2.1% on the same basis. On a month-on-month basis, the income was up +0.4% and expenditure up +0.5%. These elements are not major but they do indicate a tightening in household financial budgets.Nested deep within this release was that core PCE index rose 2.9% year-on-year in July, its largest rise since February and above the Fed's target and comfort zone. Tariff costs are getting the blame. Financial markets noticed.And that is the same sort of tightening indicated by the widely-watched University of Michigan sentiment survey. Its final August version fell back markedly from its initial readings, a clear indication households are finding it tougher. It is now -14% lower than a year ago. The Biden boom is now just a memory.On the factory floor, the latest indicators are shifting down too. The August Chicago PMI headed south quite sharply to be -10% below year-ago levels.And the US seems to be losing the tariff war it started - and Americans are paying the tariff-taxes. The latest trade data for July shows that the US merchandise trade deficit jumped to -US$104 billion in the month, exactly the same as July a year ago, and far above expectations of -US$90 bln deficit. It is their largest in four months. Imports jumped +7.1% from a month earlier, led by industrial supplies, capital goods, food, and consumer goods. Meanwhile, exports slipped -0.1%.Certainly, American farmers are not happy. And they have a President who probably doesn't even know where Pakistan is, let alone most other simple facts.In Canada, they got a sharp dose of shock in their Q2-2025 GDP result from the sharp turn on them from their southern neighbour. Their GDP fell -0.4% in the quarter and cancelling out the +0.5% gain in their first quarter. Year-on-year their GDP is still up +0.9% however.Across the Pacific the economic data is generally much more positive. South Korea's retail sales surged +2.5% in July from June, a big jump from a revised +0.7% increase in June and marking the fastest growth in over two years. From a year ago it is up +2.4% and that too is the most since January 2022.South Korean industrial production grew solidly in July as well, up +5.0% from a year ago.After a good gain in June, Japan's industrial production fell -1.6% in July, reversing a +2.1% June gain and much more than the -1.0% decline anticipated.Japanese retail sales only rose by +0.3% in July from a year ago, slowing sharply from a downwardly revised +1.9% gain in June and falling well short of market expectations for a +1.8% increase.But Japanese consumer confidence actually rose in August to its best level of the year with gains across all surveyed questions.We should also note that protests in Jakarta on Friday that turned deadly have put Indonesia on edge. They have spread over the weekend. Canberra will be watching nervously.In Europe, the ECB's survey found that consumer inflation expectations were stable ("well anchored") in July at 2.6% for the year ahead.Globally, air passenger demand was up +4.0% in July, driven by the Asia/Pacific +5.7% rise and held back by the North American +1.9% rise. Most of this is due to international travel. Meanwhile, air cargo traffic was even stronger in July, up +5.5% from a year ago, up +6.0% for international trade. Asia/Pacific was the strongest region here too, up +11.0% for international cargoes. But North American international cargo volumes only rose +1.5%, the weakest global region.The UST 10yr yield is now at 4.23%, unchanged from Saturday, but down -3 bps from a week ago. The price of gold will start today at US$3,447/oz, up another +US$5 from Saturday, and close to a new record high, but basically a measure of the USD markdown. A week ago it was at US$3,371/oz so a net +US$76 gainAmerican oil prices are again little-changed at US$64/bbl with the international Brent price holding just under US$67.50/bbl.The Kiwi dollar is at just under 59 USc and unchanged from Saturday at this time, up +30 bps for the week. Against the Aussie we are holding at 90.1 AUc. Against the euro we are unchanged as well at 50.5 euro cents. That all means our TWI-5 starts today at just under 66.5, and unchanged from Saturday, up +20 bps for the week.The bitcoin price starts today at US$109,022 and up +0.5% from this time Saturday. But is down -6.7% for the week. Volatility over the past 24 hours has been low at just on +/- 0.5%.You can get more news affecting the economy in New Zealand from interest.co.nz.Kia ora. I'm David Chaston. And we will do this again tomorrow.
Topic I: Empathy & Upholding Dignity in Today's Society Topic II: Math Marvels: Numerate by Nature; Nested in Nature…Counting on the Creator Introduction and NEWS Presenter(s): Qayyum Rashid Imam Touqeer Khan Guest(s): Imam Sabahuddin Ahmedi Prof. David Howe Fowzia Shah Rev. Prof. Wilkinson Prof. Victoria Simms Prof. Yang-Hui He Producer(s): Maleeha Mahmood & Salman Khokhar Researcher(s): Maimuna Hydra & Tooba Daud
Our heroes scale a mountain and disturb some birds... Gameplay @ 4:59 Thanks to Max @ MTM Printworks for the PC minis! Visit https://www.mtmprintworks.ca/ Thanks to Bookwyrm Games for the aforementioned coin... we love physical props! Visit https://bookwyrmgames.com/ Using Daggerheart by Darrington Press and Critical Role! #daggerheart #darringtonpress #criticalrole Visit our Patreon ~ patreon.com/TheatreoftheMindFlayer Due to the improv nature of RPG content, some themes and situations that occur in-game may be difficult for some. If certain episodes or scenes become uncomfortable or traumatic, we strongly suggest taking a break or skipping the episode. Always look to a professional if concerned about your mental health. Follow us on Instagram: @theatreofthemindflayer And Bluesky: @mindflayerpod.bsky.social Contact us at: theatreofthemindflayer@gmail.com Jacob Machin is our DM: @jacob.ryan.machin Peg Leg Pete is played by Danielle Butlin: @danielle.butlin Anna Lou is played by Hercules Mayes: @theballadofherculesmayes Lucky is played by Brandon McEwan: @ brandonmcewaan
In this episode, we're tackling one of the most fascinating storytelling techniques in tabletop gaming—and no, we're not talking about "flashback mechanics" or "framing devices." The hosts explore the art and craft of nested narratives, diving into why stories within stories aren't just narrative flourish but rather a powerful tool for creating immersive, multi-layered gaming experiences.Whether you're a seasoned GM who's experimented with tales-within-tales or a newer Game Master wondering how to weave multiple narrative threads without losing your players, this episode delivers practical insights with the kind of hard-won wisdom that only comes from years of spinning interconnected stories around the table.We dive deep into the world of layered storytelling and explore how nested narratives, character backstories, and multi-level plot structures can enhance rather than complicate the gaming experience.Topics Covered:The psychology of stories within stories: how layered tales create depth and engagementCharacter-driven nesting: when PC backstories become adventures themselvesSystems that support nested storytelling: Blades in the Dark, Burning Wheel, and Chronicles of DarknessManaging complexity: keeping multiple narrative threads coherent and compellingThe social contract of nested stories: when to embrace or simplify your narrative approachHow constraints and structure in nested stories fuel creativity rather than confuse itPlayer agency in nested narratives: maintaining choice across multiple story layersSo grab your dice, your favorite beverage, and maybe dust off that campaign notebook with all those interconnected plot threads—we're diving into every reason why stories within stories deserve more love at your gaming table!Join host Nick Perron as he draws from his expertise in the TTRPG space to explore the cutting edge of game design with creators who are pushing boundaries and making magic happen one dice roll at a time.→ Tabletopped's Stuff:→ Tabletopped's website→ Patreon→ Instagram→ TwitterCheck us out on Patreon! We have a new monthly pod as well as behind the scenes clips that you can get on a secret Spotify feed! We will also be dropping some more treats from time to time!Theme music by Mitch Poulin
UK PROPERTY MARKET WEEKLY UPDATE — Week 28, 2025 Welcome to the 28th UK Property Market Stats Show of 2025 — your go-to weekly YouTube ‘TV Show' on the UK property market. This week, I'm joined by Alice Bullard, boss lady of Nested, as we unpack the key headlines from the 28th week of 2025, ending Saturday 20th July 2025 ▶️ Watch on YouTube: https://youtu.be/_THPOlLtKaE
I have to admit, even I got stuck...Recently, I was working on the onboarding journey for my Circle community.What started as a flexible journey inside a Miro board very quickly became a complex map that became impossible to use. With every new insight we wanted to add came questions about where it should go and how it should be defined. Due to these meta-level questions, we lost momentum, and the entire process slowed to a halt. Unintentionally, I had created a journey structure that was simply too complex to be useful in practice.Finding the right balance between structure and flexibility, as well as richness and overview, in your journeys is a challenge many of us face. That's why it's the next big problem we tackle in our Journey Management Playbook series.In the past episodes, we've used AI to generate a journey and then verified it to build trust. Now, we need to make it truly manageable.The core issue is that we often treat journey maps as containers for all information, when their true power lies in driving action. So, as we've said often, we need to shift our mindset from "journey mapping" to "journey management".The key is a simple yet powerful framework for structuring your journey. * What if the most effective journey had a specific, limited number of lanes?* What if there was a rule for how many steps you should have (maximum)?* What if there was a simple way to handle complexity without cluttering your main map?In this episode, Tingting reveals the proven framework that helps you answer these questions.With this framework, you'll be able to transform your map from a static document into a practical tool that teams can use to make informed decisions.Heads-up, this is another deep-dive where we get into the nitty-gritty details. We spend a lot of time sharing our screen, so if you're listening to the audio-only version, I highly recommend opening the accompanying slides to follow along visually. We've also included timestamps in the description, so you can easily jump back to a specific topic later on.Be well, ~ Marc--- [ 1. LINKS ] --- Playbook Slides - https://go.servicedesignshow.com/08gplSign up for TheyDo - https://go.servicedesignshow.com/scjwb--- [ 2. GUIDE ] --- 00:00 Welcome to Episode 503:00 Meet Tingting: Journey Coach05:00 Short articles at the end06:00 Series Recap07:00 Next Steps: Filling Your Journey10:00 Action-Biased Journeys15:30 Simplifying your journey17:30 Workflow First: Not Just Visuals19:55 Journey Map Evolution (V1 vs V2)27:00 Why Fewer Lanes Work29:10 Triple Diamond Workflow33:40 Framework Over Flexibility38:30 Nested journeys41:20 Lane Owners & Stakeholders45:30 Offboarding Journey Example49:00 Automatic Data Roll-Up50:00 Actionable Insights > Stories54:15 As-Is vs. To-Be Approaches1:00:30 Key Takeaways: Structure Tips1:04:00 Next Episode Preview1:04:50 Connect With TheyDo --- [ 3. FIND THE SHOW ON ] --- YouTube ~ https://go.servicedesignshow.com/journey-management-playbook-05-youtube Spotify ~ https://go.servicedesignshow.com/journey-management-playbook-05-spotifyApple ~ https://go.servicedesignshow.com/journey-management-playbook-05-appleSnipd ~ https://go.servicedesignshow.com/journey-management-playbook-05-snipd
Fractal Nested Parallel Universes part 1 ~ Cannabis Talk x Nugget of Zen Episode 187 - 000 ADZ ~ The (Almost)Daily ZenCast
‘I thought, okay, well it worked for Lady Godiva, didn't it? This whole naked stuff? So let me give that a try. I felt like it was the only option.'Just as it worked for Lady Godiva, so it has for Hannah Bourne-Taylor, the campaigner, naturalist and writer who has spent years fighting for change to help Britain's bird population — and particularly the swift.• Listen to Country Life podcast on Apple Podcasts• Listen to Country Life podcast on Spotify• Listen to Country Life podcast on Audible After spending years overseas in places where she was surrounded by birds and nature, Hannah was dismayed on her return to see how little is being done to help preserve wildlife — and particularly with regard to her favourite bird, the swift. And after deciding to do something about it, she launched the campaign which has now taken years of her life — and which, as she tells James Fisher on the Country Life Podcast, has seen her enjoy a blaze of publicity by marching up and down Whitehall without a stitch on, in a desperate, yet wildly successful, publicity stunt.She tells James about the swift, their plight, and how the simple introduction of one or two ‘swift bricks' added to each new build house could have an enormous impact at negligible cost, by providing safe nesting for birds whose former favourite spots have increasingly disappeared due to modern construction techniques.Hannah also talks about her love of nature in general and the struggles she's faced, from battling apathy and indifference to hastily adjusting a stick-on G-string in the House of Lords toilets. She also tells a tale from an earlier time in her life, when a tiny lost fledgling nested in her hair as it recuperated before rejoining its family.It's a fascinating glimpse in to the mind of a woman who is in equal measure strong, brave, eccentric and passionate. Once you've listened, we'd highly recommend Hannah's books for more: her latest, Nature Needs You, about her battle to save the swift, and Fledgling, her story that rewrites ‘the conventional boundaries of the relationships people have with animals'.Episode creditsHost: James FisherGuest: Hannah Bourne-TaylorEditor and producer: Toby KeelMusic: JuliusH via Pixabay Hosted on Acast. See acast.com/privacy for more information.
FREE ACCESS to Introduction to Group and Team Coaching: https://www.igcompany.co.uk/gtcnow Why is team coaching often messier, harder and more rewarding than we expect? In this episode, we dive into one of the most nuanced areas of our work: team coaching. If you've ever been asked to work with a team after coaching an individual, perhaps a senior leader, you may have felt that wave of uncertainty: Can I do this? What do I need to know? Am I ready? We've been there too. Team coaching is richly rewarding, but it's also layered, unpredictable, and deeply human. Through this conversation, we unpack many of the real-world complexities you'll encounter when stepping into this space to show you just how powerful and transformative this work can be. We talk about: Team coaching starts early: success depends on pre-contracting, stakeholder conversations, and clear groundwork before any workshops begin. The team leader's presence is complex: they may influence or disrupt dynamics; sometimes they lead, other times they step back too far. Nested systems within teams matter: old rivalries, power imbalances, and “ghosts of past managers” can quietly shape the group dynamic. Emotional realities are unavoidable: burnout, reluctance, and anxiety about visibility are common and need sensitive handling. The coach must stay present and neutral: it's easy to be pulled into the team's dynamics, but observation without judgement is key. Beware the pull of belonging: coaches can be tempted to become “one of the team,” especially if they miss team environments from past roles, but boundaries are crucial. We wrap up by reminding ourselves (and you) that team coaching is perfectly messy. There's no tidy formula, but with curiosity, courage, and structure, it becomes one of the most impactful forms of coaching there is. If you're curious about stepping into this work, we invite you to access our free introduction to group and team coaching course. Whether you're a coach, a team leader, or someone wanting to navigate team dynamics with more skill and confidence, this is a great place to begin. Key Lessons Learnt: Team coaching starts before the coaching begins. Pre-contracting and alignment conversations are critical. Nested systems matter. Power dynamics, past relationships, and unspoken tensions affect everything. Psychological safety isn't guaranteed. It must be created, respected, and nurtured. You are not a team member. As a coach, your role is to observe the system without being absorbed into it. It's okay to feel uncertain. Team coaching is messy by nature, embrace the ambiguity. Timestamps: 00:30 – The reality of being asked to coach a team 01:56 – When the team leader is part of the coaching 03:22 – Nested relationships and power dynamics 05:16 – Creating psychological safety and trust 06:40 – Contracting with the whole team vs. individuals 08:09 – When team members aren't fully invested 10:19 – Blurred team boundaries and who should be in the room 11:45 – The “ghosts” of past leaders and emotional baggage 13:37 – What to do when someone questions your method 14:35 – Anxiety, exposure, and resistance in team coaching 16:29 – Managing your own bias as the coach 17:53 – The danger of “falling in love” with the team 19:28 – Supervision and support in navigating complexity 20:54 – There's no one way: team coaching is perfectly messy 21:24 – Free access to the introductory module Keywords: team coaching, complexities of team coaching, coaching team dynamics, psychological safety in teams, coaching resistant teams, coaching team leaders, nested systems in teams, coaching in matrix organisations, team coaching training, group coaching for leaders, how to coach a team, free team coaching course, Links: Free Intro Course: https://www.igcompany.co.uk/gtcnow Main Website: https://www.igcompany.co.uk
In this episode, Jake and Michael discuss using interfaces as a dictionary of constants, working with and testing inputs passed down multiple layers of the application, and refactoring legacy code with PHP's ArrayAccess interface.
This week, I'm talking about nested groups in Windows Active Directory and the security risks they pose. Active Directory allows administrators to attach one group to another—often called nesting. While nesting can simplify account administration and permission management, it can also create real opportunities for attackers if...
INT. SUBCONSCIOUS MIND – NIGHT.A man stares into a spiral.A voice enters the room.The loop begins.What starts as a podcast quickly becomes a paradox:Are you listening… or are you being rewritten?In this psychological-thriller-meets-transformational-masterclass, Greg invites Adam Cox—Harley Street hypnotherapist and host of The Hypnotist podcast—into the Open Loops mind-lab to detonate the outdated constructs of traditional therapy.Together, they explore:
Home Lab is back, with Advantage licenses deploying next week, and many people installing VCF on home NUCs, there is plenty of momentum around things to learn and play with ! Marc Crawford talks about his learnings!
Chelsea Barbine, a Postpartum Health Coach, challenges the way we think about motherhood saying we are forever postpartum.After witnessing the stark contrast between the abundant resources available for newborns and the limited support for new mothers, Chelsea founded Core Care Cultivate. Her mission is to ensure that mothers receive the care and attention they deserve throughout their entire motherhood journey. If you're interested in joining Chelsea's community, you can find her podcast "Postpartum Better" on all major platforms, join The Cultivate Crew online, or explore her pre-birth course "Nested and Nourish" and follow her on social media @chelsea.barbine. Her Story is hosted by Kathy Romano and airs Sunday mornings at 7am on 93.3 WMMR-FM in Philadelphia. Follow Her Story on Instagram for a first look at each week’s guest.
Text us your sleep questions.Welcome to Season 2 of Creating Well-Rested Families! In this kickoff episode, I'm catching you up on what's been happening behind the scenes, sharing some heartfelt reminders for moms in the thick of it, and, of course, giving you some helpful baby and toddler sleep tips. Plus, I'm unveiling some exciting changes coming to Nested to Rested Sleep!✨ Here's what you'll hear in this episode:✅ Life and business updates (hello, new season!)✅ Encouragement for moms navigating sleepless nights✅ Practical sleep tips to help your little one rest better✅ A sneak peek at what's new with Nested to Rested SleepSponsor Spotlight: This episode is brought to you by Hungryroot! If meal planning, prepping, and grocery shopping feel overwhelming, Hungryroot makes it easy. Get delicious, healthy meals customized to your needs and spend more time with your family. Grab 40% off your first order at https://www.nestedtorestedsleep.com/hungryrootOther links mentioned: FREE WEBINAR: 6 Steps to End Your Baby's Night Wakings: https://www.nestedtorestedsleep.com/night-wakings-webinarBLOGS: Toddler Bedtime Routine to Help Your Child Sleep Through the NightHow To Keep Things Spicy And Strong With Your Partner After Having A Baby
In this episode, we are joined by my colleague, Dr. Robin Neuhaus, to discuss recent research of ours on Perinatal Mood Disorders (PMADs) and parenting supports. We highlight the stigma associated with PMADs, leading to underreporting and inadequate support. We emphasize the need for improved screening methods, increased awareness among healthcare providers, and accessible resources for parents. The conversation also touches on the impact of parental leave policies and the importance of support networks. We conclude by advocating for greater inclusivity in research and resources, recognizing the diverse experiences of caregivers. For information on the study featured and this episode please visit Nested and @nested.institute on instagram.
UK PROPERTY MARKET WEEKLY UPDATE Welcome to the third UK Property Market Stats Show of 2025, your go to weekly one hour documentary of the UK Property Market on YouTube This week, I'm joined by the awesome Alice Bullard, CEO of Nested, to delve into the key property market headlines for Week 3 of 2025. The YouTube Show - https://youtu.be/04SXtSzeZvo . ✴️ UK Property Market Highlights this week . ✅ Listings (New Properties on the Market) 34.9k new listings this week (last week 33.7k) That's 17% higher than Week 3 of 2024 YTD and 14% higher YTD compared to 2017/18/19. ✅ Price Reductions (% of Resi Stock) 19.9k Price Reductions this week - meaning approx. 14.8% of Resi sales stock this month has been reduced. To compare, 7.8% of residential sales stock reduced in December (always a lower % in Dec). For comparison, 11.1% od stoics reduced in November and 11.9% average in 2024, though the long-term 5-year average is 10.6%. December traditionally sees a dip in this metric. ✅ Total Gross Sales (Agreed Sales) 25.7k UK homes sold STC this week, up from 23.8k last week in Week 2 That's 35% higher YTD compared to 2024 and 43% higher than 2017/18/19 YTD levels. ✅ Sale-Through Rate (Monthly in Arrears) Approx. Run rate of 14.2% of Resi stock sold stc in Jan. For comparison, 10.61% of residential sales stock sold in December 2024, compared to 8.79% in December 2023. 2024 monthly average: 15.3%. Long-term 7-year average: 17.9%. ✅ Sale Fall-Throughs 23.3% of gross sales fell through this week – ad top from last week at 25.4%. Slightly below the 7-year average of 24.2%, but well below the 40%+ levels post-Truss Budget (Autumn 2022). On a monthly basis, approximately 5.4% of sales in the UK agents pipelines have fallen thru in Jan 25. For comparison, 3.8% of the December 2024 sales pipeline fell through (Dec is always lower) (2024 average: 5.36%). ✅ Net Sales (Gross sales for the week less Sale Fall Thrus for the week) 19.7k net sales this week, compared to a typical week 3 average of 18.1k. Last week (Week 2 2025) - 17.7k. 2025 YTD is 38% higher than compared to 2024 YTD and 39.7% higher than YTD 2017/18/19. ✅ Residential Sales Stock on the Market 605k properties on the market at the end of December 2024 (down from 677k in November). Historical comparison for end of December: * 2023: 560k * 2022: 481k * 2021: 342k * 2020: 543k * 2019: 545k. ✅ Residential Sales Sold STC Pipeline 441k sales agreed but not yet completed at the end of December 2024. Historical comparison for December : * 2023: 359k * 2022: 373k * 2021: 468k * 2020: 548k * 2019: 310k. ✅ UK House Prices (£/sq.ft) As always, the £/sq.ft metric predicts Land Registry figures 5 months in advance with 92% accuracy (the orange line of the graph). December's final figure: £339/sq.ft. * November: £342/sq.ft * August: £334/sq.ft * December 2023: £322/sq.ft This means house prices have risen 5.28% in the last 12 months. Local Focus this week - Wembley
☕The member version of this episode has an extra TEN MINUTES of pre-show conversation. To hear the whole convo you can back on Kofi for just $5/month!☕Today we're talking about Nested by Ortiel! A game about opening menus and finding God. This game was suggest be Amet! Thank you Amet!Play Nested in your browser! Keep up with Ortiel on their website!---Discussed in the episodeCookie Clicker'Eggman Game' Full Sketch | I Think You Should Leave with Tim Robinson on YouTubePowers of Ten™ (1977) by Eames Office LLC on YouTube---Visit our website!Support the show on Kofi!Follow us on Twitch!Follow the show on Bluesky!Check out The Worst Garbage Online!---Art by Tara CrawfordMusic by _amaranthineAdditional sounds by BoqehProduced and edited by AJ Fillari---Timecodes:(00:00) - Stray Kids and local holidays (01:55) - To learn more about the mummer's day parade join our Kofi! (or search it up I guess) (03:10) - Yaaaaaay... (03:51) - What is Nested? (05:25) - Shoutout to Amet! (06:30) - Have we all played Cookie Clicker? (08:22) - Nested. (13:07) - Time to get existential (21:13) - Who are WE? (24:36) - Zooming out (26:15) - Time for Controversy (32:05) - You gotta shift focus to see the beauty of the universe. Wow. (33:52) - A shipment of Big Takeaways is arriving (34:30) - AJ's Big Takeaway (35:04) - Chase's Big Takeaway (37:41) - Kim's Big Takeaway (39:47) - Thank you Amet!! (39:56) - Cookie Clicker check-in (41:09) - Thank you for listening!
In this episode, Jake goes through some of the newer features of the View Transition API, along with some vaguer ideas that are planned for the future. Resources General view transitions docs Custom entry and exit transitions hasUAVisualTransition so you know when the UA has done its own transition view-transition-class view-transition-types Cross-document view transitions to wait for a particular element The blocking attribute to wait for a particular resource The pageswap and pagereveal events Nested view transitions The match-element vs auto discussion Scoped view transitions attr() in Chrome Safari just went and released view-transition-name: auto
Today's episode opens with a Planner Peace segment from Sarah's friend and coworker Kathleen who uses a medium-sized At-A-Glance Weekly and Monthly (available here: https://a.co/d/5tnHJZ5). This planner may appear basic but it packs a punch in terms of features (and the paper is nice, too!). Then, Sarah provides a review of the Just Scribble Plans Vertical Weekly A5 Planner (available here for preorder: https://www.shopjustscribble.com/products/plans-vertical). It's a 2-volume set and a LOT of planning real estate. Sarah then shares some ideas of things she wants to do differently with her own planning in 2025, followed by a listener question asking for an example of how "Plan a Neighborhood Party" would make its way through the Nested Goals system. Info on BLP at Home Planning 2025: theshubox.com/courses Episode Sponsors: Jenni Kayne: Check out their amazing gifts, from candles to their iconic sweaters . Visit jennikayne.com; listeners get 15% off your first order when you use code PLANS at checkout. PrepDish: Visit PrepDish.com/plans for your first 2 weeks, FREE. Learn more about your ad choices. Visit megaphone.fm/adchoices
In the blistering heat of Western Australia, a small group of weary soldiers faced an unexpected enemy. Armed with 10,000 rounds each and every ounce of determination they could muster, they were tasked with taking down an invasion force of 20,000. But their adversaries weren't elite special forces—they were emus. Yes, emus. In this episode, we dive into the tale of the Great Emu War of 1932, an infamous campaign where Australian troops found themselves outwitted and outmaneuvered by a flock of massive, flightless birds. The operation became a public embarrassment, exposing critical flaws in strategy, communication, and clarity. Using this surreal story as a springboard, we explore how lack of clear goals, vision, and alignment can doom even the most well-equipped efforts. Just like these soldiers found themselves lost and overwhelmed, many entrepreneurs struggle to set meaningful goals and find direction in their work. But it doesn't have to be that way. Tune in to learn how setting clear, purposeful goals can transform your business and life, saving you from your own version of the “Great Emu War.” And don't miss the chance to read more on this at TomFoxley.me/blog, where you'll find practical tips to align your goals, avoid wasted effort, and create the success you're looking for. ---- Blog link: https://www.tomfoxley.me/post/nested-goals
Pox, the quintessential Chiapas spirit, is probably the most mysterious Mexican drink that I've encountered in my life. It was a big part of my early 20's, but I never truly understood its technicalities or cultural relevance. Happily, thanks to Javier Oroz, who I just interviewed a few weeks ago (go check the Bacanora episode), I got to meet Zury Guindi.Zury started bottling bottling Pox back in 2011 under the umbrella of "Siglo Cero". When even mezcal was just starting to happen, he decided to dedicate his life to corn, panela and wheat instead of worshipping agave. In this episode we try to cover as much as we can about this fascinating and delicious drink. Hope you enjoy it!This episode was recorded at Som, Zury's bar in Mexico City. Nested in the heart of Condesa I can't emphasize enough how fun is to go through all their menu. You'll get to try Pox, rum, raicilla, mezcal, tequila and many other bizarre and lovely Mexican spirits.
In this week's ‘UK Property Market Stats Show' on YouTube for week ending Sunday, 22nd September 2024, Chris ‘Stato' Watkin with this week's special guest, Alice Bullard (boss lady of Nested), discuss the property market headlines for Week 38 of 2024. · Listings (New properties coming on to the market) - 37.4k UK listings this week (week 38), 38k the week before. 7.7% higher 2024 YTD than 2017/18/19 YTD average. 14.5% higher than Week 38 of 2023. · Total Gross Sales - 26.4k UK homes sold stc this week (Week 38), which 25.2% higher than the same week (week 38) in 2023. · Net Sales - 19.7k this week (19.3k last week). 32% higher than the same week in 2023 & still 16.2% higher YTD in 2024 compared to YTD 2023. · % of Homes exchanging vs homes unsold - Of the 1,091,884 UK homes that left UK Estate Agents books since the 1st Jan 2024, 582,642 of them (53.36%) exchanged & completed contracts (meaning the homeowner moved and the estate agent got paid). The remaining 509,242 (46.64%) were withdrawn off the market, unsold. In essence you a flip of the coin chance of actually selling, homeowners moving and the estate agent getting paid. · UK House Prices - Mid / Late September figures suggest a slight jump in this important metric to £343/sq.ft. For comparison - August's Figures for the Sale Agreed £/sq.ft was at £338/sq.ft, and July at £341/sq.ft. This means house prices are rising, albeit slowly. · Sale fall-throughs - Sale Fall Thrus (as a % of Gross sales Agreed) dropped to 25.1% this week. The 7 year Long Term Average is 24.2% and it was 40%+ in the two months following the Truss Budget in the Autumn of 2022.
Text us your sleep questions.Bringing you back to when I first kicked off Nested to Rested Sleep Consulting and held group sleep coaching. In this episode, I am sharing a coaching call I had with a mom who was part of the group sleep coaching. We chat about her 4.5-month-old dealing with night wakings, false starts, short naps, and their readiness to drop some night feeds and start sleep training. An important thing to remember is that things suggested to her were part of her sleep plan given their expectations and sleep goals. Keep in mind that these suggestions vary per family and can be personalized. Want a coaching call for yourself? >>>Join the Well-Rested Families Membership to make sleepless nights a thing of the past!Want a free sample baby sleep schedule?
Text us your sleep questions.Welcome to Episode 4 where we chat all about when and how to drop your baby's night feeds. Now keep in mind that this is something your baby does naturally on their own or may need a little help from you when and if you and baby are ready. This may also improve sleep for you and your family to help get you on step closer to becoming a well-rested family. In this episode we will cover: What is night weaningWhen to know if you and your baby are ready to drop some or all night feedsHelpful tips to make dropping night feeds a little easierHacks for both bottle-feeding or breastfeeding familiesCommon concerns that come with night weaningAs your certified pediatric sleep consultant and sleep bestie, I share the best methods for weaning in a responsive, gradual way. Our mission at Nested to Rested Sleep consulting is to empower, support and educate you on how to get your whole family to become well-rested. Please subscribe, review, and share with all your friends who deserve a good night's sleep as well. Relevant Blogs: Soothing LadderWhen and How to Start Night WeaningReferences: SEE SHOW NOTESWant a free sample baby sleep schedule?
EASY LISTENING DEP'T.
I have a special guest for you!!! Chelsea Barbine!! Her unpopular opinion, we are forever postpartum was inspired by her own journey of becoming a mama! She is the Founder of Core Care Cultivate, Chelsea Barbine, is on a mission to help women embrace motherhood without sacrificing their sleep, sanity, or self-identity. Listen to this fun conversation that we have about post postpartum, and yes of course even MANIFESTING! Contact for Chelsea Barbine Chelsea@corecarecultivate.com Website: corecarecultivate.comPodcast: Cultivate with Chelsea IG: @chelsea.barbine A Note from Chelsea: May is #maternalmentalhealthawarenessmonth and in addition to a special series being released on the Cultivate with Chelsea podcast, I'm showing monetary support by donating a percentage of all Core Care Cultivate sales from the month of May with two charities. As a firm believer in education and preparation to support the transition to life after birth, and as a proud consumer of Perelel Health for almost 3 years now, I'm honored to support their pledge to raising $10million towards closing the research gap on women's health as an official #PerelelAdvocate by supporting their #FundWomensHealthCampaign. In honor of my desire to support the fellow mamas in the trenches with me, I will also be supporting the Postpartum Support International's The Climb fundraiser again this year provide support and resources to women and their families who have been affected by postpartum mood disorders. So yes, whether you purchase the Nested & Nourished: 4-Steps to Approach Postpartum with Ease course or join the June 4th cohort of The Cultivate Crew to receive daily coaching support while navigating life after birth, you will not only be supporting yourself but you'll be joining me in the mission to rewrite the postpartum narrative for the collective.
Jake and Michael discuss some of the gotchas upgrading from a previous version of Laravel to 11.x, integrating a React frontend built in parallel to its backend, nested validation, and the simplicity of using a batteries-included framework like Laravel.Show linksLaravel BootcampLaracastsLaravel Up and RunningOnramp to LaravelLaravel Shift
Both Jonathan Geltner (Absolute Music) and Gregorio Montejo (In a Green Tree) return as guests to discuss the 2019 book, Beneath the Silent Heavens, by Brian Christopher Moore. Nested in the discussion of the book, we also discussed typology vs allegory, Noe's Ark, Medieval Mystery Plays, the Welsh poet David Jones, the French poet Charles Péguy, the American tale tellers R. A. Lafferty, Gene Wolfe and Tim Powers, and what makes good fantasy. What does make good fantasy anyway? Seriously, we covered a lot in this one, so don't miss it! Brian Moore's Links: Beneath the Silent Heavens Angelico Press Christ the Symphonic Adventure Substack ************************************************************************************************************* Follow me on Twitter @AaronIrber Donate to my Patreon - I Might Believe in Faeries https://www.patreon.com/imightbelieveinfaeries Like my Facebook page - I Might Believe in Faeries Battle Of The Creek by Alexander Nakarada | https://www.serpentsoundstudios.com Music promoted by https://www.free-stock-music.com Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/ Logo Art by Linnea Kisby *************************************************************************************************************
@JordanBPeterson Exploring the Philosophical and Scientific | Dr. Daniel Dennett | EP 438 https://youtu.be/VWpm2NOF2Zw?si=6YS2G0xqn9-b_HCS The whole conversation is here in "no wait no ads" https://youtu.be/6zrawpzwRf0 Paul Vander Klay clips channel https://www.youtube.com/channel/UCX0jIcadtoxELSwehCh5QTg Bridges of Meaning Discord https://discord.gg/J6BqymNg https://www.meetup.com/sacramento-estuary/ My Substack https://paulvanderklay.substack.com/ Estuary Hub Link https://www.estuaryhub.com/ If you want to schedule a one-on-one conversation check here. https://calendly.com/paulvanderklay/one2one There is a video version of this podcast on YouTube at http://www.youtube.com/paulvanderklay To listen to this on ITunes https://itunes.apple.com/us/podcast/paul-vanderklays-podcast/id1394314333 If you need the RSS feed for your podcast player https://paulvanderklay.podbean.com/feed/ All Amazon links here are part of the Amazon Affiliate Program. Amazon pays me a small commission at no additional cost to you if you buy through one of the product links here. This is is one (free to you) way to support my videos. https://paypal.me/paulvanderklay Blockchain backup on Lbry https://odysee.com/@paulvanderklay https://www.patreon.com/paulvanderklay Paul's Church Content at Living Stones Channel https://www.youtube.com/channel/UCh7bdktIALZ9Nq41oVCvW-A To support Paul's work by supporting his church give here. https://tithe.ly/give?c=2160640
———An Infinite Path podcast official URL http://www.aninfinitepath.comSpotify | iTunes | YouTube | Overcast FM | Stitcher | Player FM
In this JCO Precision Oncology Article Insights episode, Mitchell Elliot provides a summary on "Prediction of Benefit From Adjuvant Pertuzumab by 80-Gene Signature in the APHINITY (BIG 4-11) Trial," by Krop, et al published on January 18th, 2024. TRANSCRIPT Mitchell Elliott: Hello and welcome to JCO Precision Oncology Article Insights. I'm your host, Mitchell Elliott, an ASCO Journal Editorial Fellow. Today, I will be providing a summary of the article titled "Prediction of Benefit from Adjuvant Pertuzumab by 80-Gene Signature in the APHINITY (BIG 4-11) Trial" by Dr. Ian Krop on behalf of the APHINITY Steering Committee and Investigators. HER2 epidermal growth factor receptor 2 positive, or HER2 positive breast cancer is characterized by overexpression of the HER2 protein. HER2 is an extracellular receptor that binds with itself and other proteins on the cell surface to facilitate rapid growth and division of cancer cells. Historically, HER2 positive breast cancer carried a worse prognosis than other subtypes. Anti-HER2 therapy with the monoclonal antibody trastuzumab in combination with chemotherapy has been shown to significantly improve clinical outcomes. Pertuzumab, another anti-HER2 monoclonal antibody, binds to a different site on the HER2 protein and has been shown to further disrupt HER2 signaling and improve clinical outcomes. Primary results from the APHINITY trial, this trial, served as the basis for dual HER2 blockade, combining trastuzumab and pertuzumab with chemotherapy in the adjuvant setting. This data helped establish dual HER2 blockade as the standard of care in many jurisdictions around the world. Understanding patients who do not derive benefit from the additional anti-HER2 therapy is paramount for delivering personalized and effective care while minimizing treatment-related side effects. Understanding the underlying biology of patients who do not drive a response may provide insight into areas of future drug development and integration of novel therapies into future clinical trials. The clinical definition of HER2 positivity encompasses those that are most likely to have HER2-driven tumors, but previous work has demonstrated that this clinical-pathologic definition does not accurately reflect the molecular heterogeneity of this subtype. These authors completed a translational secondary analysis of the phase III APHINITY trial using nested case-control methods with RNA-seq data derived from primary tumors of patients enrolled in this trial. Both the MammaPrint and Blueprint classifiers are commercially available assays run on microarray data using previously published and validated gene sets. MammaPrint classifies tumors as high or low risk, while Blueprint classifies tumors into luminal, basal-like, or HER2 subtypes. Luminal A tumors are MammaPrint low risk luminal classification, while luminal B tumors are classified as MammaPrint high risk with conventional luminal classification. In order to facilitate these analyses, RNA-seq data was converted into pseudo microarray-based sequencing using a bridge study from an independent cohort of 75 patients. Conventional Blueprint scores for luminal type, HER2 type, or basal type were calculated for each sample. The subtype with the highest score of the three was the conventional subtype reported for the tumor. The Blueprint subtype was further sub-stratified as a single-activated or dual-activated subtype. Single-activated samples represented the dominant enriched pathway in each tumor, while dual-activated subtypes were assigned if there was no statistical difference between the two dominant pathways. The primary endpoint was invasive disease-free survival, IDFS, and was stratified by genomic subtype and treatment arm. IDFS was defined as the time from treatment random assignment until the date of first recurrence of ipsilateral invasive breast tumor, recurrence of ipsilateral local-regional invasive disease, distant disease recurrence, contralateral invasive breast cancer, or death from any cause. Patients without an event at the last follow-up date were censored. The median follow-up time was 45.4 months. 964 patients were evaluated for MammaPrint and Blueprint subtypes. One patient was excluded as they were low risk by MammaPrint. The final cohort included 963 patients in this nested case-control study with IHC/FISH-defined HER2 positive tumors. Two-thirds of the patients were hormone receptor positive. Most patients were over the age of 35, 83% had lymph node involvement, and 83% of patients received anthracycline-containing chemotherapy. Blueprint classified 50% of patients as luminal B type, 28% as HER2 positive, and 22% as basal type. Most of the luminal B tumors were single-pathway activated, while only around 50% of HER2 type and basal type tumors had single-activated pathways. Similar clinical and treatment characteristics were observed between the conventional Blueprint subtypes as well as the single and dual-activated subtypes. Nested case-control inverse probability-weighted corrected multivariate Cox regression analysis revealed no significant difference in IDFS among the different conventional Blueprint subtypes. Conventional Blueprint subtypes were also not prognostic of benefit from the addition of pertuzumab. The authors then investigated whether there was a significant difference in IDFS in patients with only single gene pathway activation. Interestingly, patients classified as Blueprint basal single-activated subtypes were more likely to have an IDFS event, with a hazard ratio of 1.69 and a 95% confidence interval of 1.12 to 2.54. This captures the worst prognosis of molecularly defined basal-like tumors, remembering that all of the patients included in this cohort were, by ASCO-CAP guidelines, HER2 positive. In comparing the benefit from the addition of pertuzumab amongst the patients with single-activated subtype, there was no significant improvement in IDFS events with the addition of pertuzumab. There was a non-significant numerical benefit with the addition of pertuzumab in HER2 single subtype, suggesting that patients with dominant HER2-related signaling may derive more benefit from this combination therapy. To help account for confounding variables, multivariate analyses were pursued to correct for routine clinical factors such as age, nodal status, hormone receptor status, as well as the use of anthracycline in addition to the conventional and single-activated pathway subtypes. Of all the clinical factors included in these analyses, only nodal status was significantly associated with IDFS in all of the conventional and single-activated subtypes. This reflects the important consideration of both clinical and genomic risk in patient assessment, as both have strong implications on treatment outcomes. In summary, Blueprint HER2 tumors, which consist of both single and dual pathway-activated tumors, did not clearly distinguish those who derived pertuzumab benefit. There was a further non-significant benefit noted in HER2 single pathway-activated tumors. This suggests that tumors with multiple mitogenic pathways may have an inferior response to HER2 targeted therapy compared to single-activated tumors. Overall, this article presents further insight into the molecular heterogeneity within the clinical-pathologic defined HER2 positive breast cancer subtype. The use of a commercially available gene signature assay was able to distinguish a subset of patients with a worse overall clinical outcome regardless of treatment received. Further analyses are required to validate and assess the utility in deploying this strategy in the treatment of patients with early HER2 positive breast cancer, but there is a suggestion that the 80-gene signature may refine patient selection, optimize treatment planning, and improve long-term outcomes for this patient population. Thank you for listening to JCO Precision Oncology Article Insights, and please tune in for the next topic. Don't forget to give us a rating and review and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts. The purpose of this podcast is to educate and inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
In this episode, we unravel nested tag structures. Chad and Dax break down lists, TOC, footnotes, and tables. Learn what the most basic way to create a list structure is and how Dax had to hit the books once again to make sure he wasn't telling tales. Chad talks about footnotes and references and why you might hear "Link Link" in your TOC elements. If you struggle to understand which tags get nested inside others, then you definitely want to listen to this episode!
In today's episode, Sarah shares how her year is shaping up so far, including a report on her planner choices for the year. Then, the episode is devoted to a deep dive into Nested Goal Setting - her method for setting goals and identifying tasks based on time horizon from daily to yearly. She reviews her methodology in detail and answers common questions from "wait, isn't that a LOT of time spent planning?" to those about which tools she uses and when to refer to each list. Learn more about your ad choices. Visit megaphone.fm/adchoices
CSS :has() is out in all browsers and Wes and Scott have got the top 10 reasons you should start using :has() now. Show Notes 00:25 Welcome 02:28 Syntax Brought to you by Sentry 03:02 Overview of :has 07:09 The anywhere selector 09:41 Previous element 12:59 Layout targetting 15:45 Form validation styling 17:51 All siblings 21:07 Quantity queries 24:19 Empty children 24:56 Nested dropdown navs 26:36 Attribute matching Hit us up on Socials! Syntax: X Instagram Tiktok LinkedIn Threads Wes: X Instagram Tiktok LinkedIn Threads Scott: X Instagram Tiktok LinkedIn Threads
Welcome to The SaaS CFO Podcast! In this episode, we dive into the world of Financial Planning and Analysis (FP&A) with Taimur Abdaal, the founder and CEO of Causal. Taimur shares his background in mathematics and programming, and how that led him to start Causal, a number crunching tool that simplifies financial modeling and planning. He talks about the journey of building Causal, from its early days to raising funding and scaling the business. Taimur also discusses the company's approach to go-to-market strategy, product development, and the key metrics they focus on. If you're interested in the intersection of tech, finance, and entrepreneurship, this episode is a must-listen. Stay tuned to gain valuable insights into the world of SaaS and FPA! Show Notes: 00:00 Data scientist at Nested worked on automating financial models, prompted the idea for a better number-crunching tool. Spreadsheets have not evolved much in 40 years. 04:38 Felt right to quit job, started project, gained interest. 07:11 Product focuses on easy initial use, scalable complexity, self-serve flow, and product-led growth strategy. 25% revenue from self-serve, majority from higher touch motion. 10:43 Early investors were found through connections, securing $1 million. 14:32 Access to networks and warm introductions important for fundraising. Pre-seed and seed stages focus on market size, team strength, and initial traction. Series A requires high growth rate. 17:29 Next focus is out-of-the-box reporting, easily linked with CRM. Links: SaaS Fundraising Stories: https://www.thesaasnews.com/news/casual-secures-15-million-in-series-a Taimur Abdaal's LinkedIn: https://www.linkedin.com/in/taimurabdaal/ Causal's LinkedIn: https://www.linkedin.com/company/causalhq/ To know more about Ben check out the links below: Subscribe to Ben's daily metrics newsletter: https://saasmetricsschool.beehiiv.com/subscribe Subscribe to Ben's SaaS newsletter: https://mailchi.mp/df1db6bf8bca/the-saas-cfo-sign-up-landing-page SaaS Metrics courses here: https://www.thesaasacademy.com/ Join Ben's SaaS community here: https://www.thesaasacademy.com/offers/ivNjwYDx/checkout Follow Ben on LinkedIn: https://www.linkedin.com/in/benrmurray
2:26:33 – Frank in New Jersey, plus the Other Side. Topics include: Nested artificial worlds, Sunoco, Times Square, rainy night, The Exit Ramp, Laurie Anderson – Sharkey’s Day, David Letterman, Dope Lemon, The Field Mice, Boston Trip, Cool Beans Outcast, trucking, TV in the 20th Century, NYC flooding, whatever happened to the metaverse, and much more… […]
In this episode, John interviews Taune Lyons, a licensed marriage family therapist, about attachment styles and how they impact our relationships of all kinds - not just romantic. They also start processing what was happening in real time during the interview, unintentionally demonstrating what happens in therapy rooms. And finally, John hears the term "big dick energy" for the first time. You can find Taune on Instagram @taunelyons or her website: www.Taunelyons.com Roughly ten minutes of self help in a shot glass. If you're looking for a wine glass, you've come to the wrong place. Marriage family therapist and best-selling author, John Kim, shares his life and love revelations as well as insights from his sessions. He pulls the curtain back and documents his journey as a therapist but more importantly, as a human being. Meet him at -> https://www.theangrytherapist.com Join his private communities -> https://theangrytherapist.circle.so/home Get his daily texts here -> https://www.theangrytherapist.com/text
You've no doubt heard about VMware Cloud Foundation (VCF), VMware's full-stack SDDC solution for implementing a modern private cloud. With the VCF Holodeck Toolkit toolkit, customers can quickly get fully functional nested VCF lab up and running and start getting hands-on with all aspects of the VMware Software-Defined Data Center (SDDC). Watch the video of this episode Watch all VMware Explore Recap episodes
Array Cast - September 1, 2023 Show NotesThanks to Bob Therriault, Lynn Sutherland and Adám Brudzewsky for gathering these links:[01] 00:01:34 2023 APL Problem Solving Results https://www.dyalog.com/news/156/420/2023-APL-Problem-Solving-Competition-Winners.htm Dyalog System Admin/Enterprise Architect opening https://www.dyalog.com/careers.htm#sysadmin[02] 00:02:18 BQN Licensing change to MPL https://github.com/dzaima/CBQN/tree/master#licensing[03] 00:03:11 Contact Stephen about q tutorials sjt AT 5jt DOT com[04] 00:04:51 Nial Programming Language https://aplwiki.com/wiki/Nial APL Farm discord https://aplwiki.com/wiki/APL_Farm Alberta Research Council/Alberta Innovates https://albertainnovates.ca/ National Resource Council https://nrc.canada.ca/en/corporate/about-nrc MaRS Institute https://www.marsdd.com/[05] 00:11:12 Queens University https://www.queensu.ca/ Mike Jenkins https://www.cs.queensu.ca/people/Mike/Jenkins https://www.linkedin.com/in/michael-jenkins-1ba84915/ Trenchard More https://en.wikipedia.org/wiki/Trenchard_More[06] 00:14:10 Procedural Programming Language https://en.wikipedia.org/wiki/Procedural_programming VAX https://en.wikipedia.org/wiki/VAX IBM PC XT https://en.wikipedia.org/wiki/IBM_PC_XT[07] 00:17:20 Nested Array Theory https://aplwiki.com/wiki/Array_model#Nested_array_theory[08] 00:18:43 Jim Brown https://aplwiki.com/wiki/Jim_Brown[09] 00:25:14 Computer Language Magazine https://archive.org/details/computerlanguage Carl McCrosky https://www.linkedin.com/in/carl-mccrosky-b936051/ Intel AVX512 https://en.wikipedia.org/wiki/AVX-512[10] 00:27:21 OpenAI https://en.wikipedia.org/wiki/OpenAI Triton OpenAI https://openai.com/research/triton[11] 00:29:31 APL 84 Helsinki https://aplwiki.com/wiki/APL_conference#1984[12] 00:31:15 Dyalog https://aplwiki.com/wiki/Dyalog_APL KX https://kx.com/ Julia Programming Language https://julialang.org/ Clojure Programming Language https://clojure.org/ Unix Operating System https://en.wikipedia.org/wiki/Unix Red Hat https://en.wikipedia.org/wiki/Red_Hat Sun Microsystems https://en.wikipedia.org/wiki/Sun_microsystems[13] 00:34:15 Matlab https://en.wikipedia.org/wiki/Matlab[14] 00:38:09 Java Programming Language https://en.wikipedia.org/wiki/Java_programming BQN Programming Language Modifiers https://mlochbaum.github.io/BQN/doc/ops.html#modifiers J Programming Language Gerunds https://code.jsoftware.com/wiki/Vocabulary/GerundsAndAtomicRepresentation[15] 00:40:39 Nial tutorial https://www.nial-array-language.org/ndocs/intro/[16] 00:42:25 Strand Notation https://aplwiki.com/wiki/Strand_notation Combinators https://en.wikipedia.org/wiki/Combinatory_logic Nial Atlas https://www.nial-array-language.org/ndocs/NialDict2.html#atlas Point free programming https://en.wikipedia.org/wiki/Tacit_programming[17] 00:44:43 eachboth https://www.nial-array-language.org/ndocs/dict/#eachboth[18] 00:46:56 q Programming Language https://code.kx.com/q/learn/startingkdb/language/ peach https://code.kx.com/q/basics/peach/ J threads https://code.jsoftware.com/wiki/Vocabulary/tcapdot#dyadic[19] 00:51:25 Nial website https://www.nial-array-language.org/[20] 00:52:37 Order of Operations https://en.wikipedia.org/wiki/Order_of_operations[21] 00:55:00 Javascript Programming Language https://en.wikipedia.org/wiki/Javascript Unary Functions https://en.wikipedia.org/wiki/Unary_functions Smalltalk Programming Language https://en.wikipedia.org/wiki/Smalltalk[22] 01:02:50 TIO Nial Examples https://tio.run/##y8tMzPn/P7EstSgxPVUhs1hBP7q4NFdHoSQxJ6cy1pqrvCizJFUBJm@oYKRgrGDy/z8A https://tio.run/##y8tMzPn/v7wosyRVQVtBS0HD0EDByEATSCsYaf7/DwA https://tio.run/##y8tMzPn/v7wosyRVQVvB0EDByEBBS8FQwej/fwA https://tio.run/##y8tMzPn/v7wosyRVQUNbwdBAwchAQUvBUMFI8/9/AA https://tio.run/##y8tMzPn/v7wosyRVQVtBw9BAwchAU0ELyFIw0vz/HwA https://tio.run/##y8tMzPn/v7wosyRVQcPQQEFDK1pXRztWU8FI8/9/AAOnline Nial Interpreter https://niallang.github.io/NIAL_WASM/[23] 01:17:48 Contact AT ArrayCast DOT Com
As the tech giant approaches its 25-year anniversary, there are questions of just how much more it can possibly grow. Investors are used to stratospheric returns. Is it time to manage expectations? Nested behind the appearance of social discontent in France is an economy that is actually thriving (10:51). And, a tribute to a true man of the woods (19:02). For full access to print, digital and audio editions of The Economist, try a free 30-day digital subscription by going to www.economist.com/intelligenceoffer Hosted on Acast. See acast.com/privacy for more information.
As the tech giant approaches its 25-year anniversary, there are questions of just how much more it can possibly grow. Investors are used to stratospheric returns. Is it time to manage expectations? Nested behind the appearance of social discontent in France is an economy that is actually thriving (10:51). And, a tribute to a true man of the woods (19:02). For full access to print, digital and audio editions of The Economist, try a free 30-day digital subscription by going to www.economist.com/intelligenceoffer Hosted on Acast. See acast.com/privacy for more information.
Lenny Levi Video https://youtu.be/XZldBiVZLFw @BrendanGrahamDempsey Metamodernism 101: What Does 'Metamodern' Mean? https://youtu.be/9BzD3wUEMaQ @crcna Synod 2022 Zachary King Interview https://youtu.be/w_AHK3v42P0 @VideoAdvice The 4th Turning https://youtu.be/JB9Up1eeHgE July Washington DC Event with Michael Martin and Spencer Klavan https://www.eventbrite.com/e/christ-and-community-in-the-modern-age-tickets-608591853617 Breakwater Festival Mannheim Germany October 27-29 2023 Event Details and Tickets: https://buytickets.at/breakwater/935800 T-shirts: https://buytickets.at/breakwater/store Discord: tinyurl.com/BreakwaterDiscord Festival Email: contact.breakwater@gmail.com Flyer https://bit.ly/breakwaterfestival2023 Join this channel to get access to perks: https://www.youtube.com/channel/UCGsDIP_K6J6VSTqlq-9IPlg/join Paul Vander Klay clips channel https://www.youtube.com/channel/UCX0jIcadtoxELSwehCh5QTg Bridges of Meaning Discord https://discord.gg/EcW3VmqP https://www.meetup.com/sacramento-estuary/ My Substack https://paulvanderklay.substack.com/ Estuary Hub Link https://www.estuaryhub.com/ If you want to schedule a one-on-one conversation check here. https://paulvanderklay.me/2019/08/06/converzations-with-pvk/ There is a video version of this podcast on YouTube at http://www.youtube.com/paulvanderklay To listen to this on ITunes https://itunes.apple.com/us/podcast/paul-vanderklays-podcast/id1394314333 If you need the RSS feed for your podcast player https://paulvanderklay.podbean.com/feed/ All Amazon links here are part of the Amazon Affiliate Program. Amazon pays me a small commission at no additional cost to you if you buy through one of the product links here. This is is one (free to you) way to support my videos. https://paypal.me/paulvanderklay Blockchain backup on Lbry https://odysee.com/@paulvanderklay https://www.patreon.com/paulvanderklay Paul's Church Content at Living Stones Channel https://www.youtube.com/channel/UCh7bdktIALZ9Nq41oVCvW-A To support Paul's work by supporting his church give here. https://tithe.ly/give?c=2160640
The Banner Synod Incomplete and Broken https://www.thebanner.org/news/2023/06/synod-2023-incomplete-and-broken @randosunited https://www.youtube.com/live/-tjNg3x-sL4?feature=share @JonathanPageau Universal History: The Symbolism of Nationalism - with Richard Rohlin https://youtu.be/XlG3QVlFpWc
Calling all pregnant mamas and moms with newborns! We've teamed up with certified pediatric sleep consultant Unnati Patel to do a series on sleep tips and hacks for newborns to toddlers!This episode is packed with so many things a new mama needs to know to help her newborn baby sleep, so SHE can sleep. Listen to Unnati describe the wake window as well as research-backed evidence that helps babies fall asleep. Then, keep an eye out for future episodes where Unnati shares similar suggestions for different age groups. This is a must-have tool for every parent!Learn more about Unnati and her business, Nested to Rested.https://www.nestedtorestedsleep.com/free-baby-sleep-resourceshttps://www.nestedtorestedsleep.com/serviceshttps://www.nestedtorestedsleep.com/newborn-baby-sleep-courseUse PAP10 for 10% off your next purchase at https://www.nestedtorestedsleep.com/.About Unnati Patel:I am a certified pediatric sleep consultant and I educate, empower, and support exhausted families to get the sleep they need and deserve. By using a customized holistic and evidence-based sleep approach to help establish healthy sleep habits in children 0-5 years of age, I help families get well-rested and able to thrive.My background is in research and public health. I worked in clinical research for over 8 years for government agencies such as the VA and CDC, and used my education to help me prepare for motherhood. Reality soon hit after I became a mom and experienced first-hand how sleep deprivation feels. So I did all the research on pediatric sleep to help sleep train my daughter around 4-5 months. From the lessons learned from her, I was able to sleep train my son at 2 months. I want to use what I have learned and been trained in to help as many families as possible go from overtired to well-rested and thriving!Follow Previa Alliance!Previa Alliance (@previa.alliance) • Instagram photos and videosPrevia Alliance Podcast (@previapodcast) • Instagram photos and videosKeep the questions coming by sending them to info@previaalliance.com or DM us on Instagram!