Podcasts about Akiko

In this episode, the host, Masako, is joined by Akiko Hoshihara—a gifted healer blending Reiki, hypnotherapy, and intuitive readings. Akiko shares her personal spiritual awakening journey and how life's challenges became gateways to deeper self-discovery and soul-aligned purpose.The conversation expands into the non-linear nature of awakening, the activation of intuitive gifts, connecting with the Higher Self, and the power of inner child and past life healing. Akiko also reminds us that even when the journey feels lonely, we are never truly alone—and our soul tribe will find us along the way.This is part one of the conversation—stay tuned for part two in the coming weeks!About Akiko:Website: Akiko HoshiharaResources discussed in this episode:What is Reiki?How to navigate your Saturn ReturnWhat is Yakudoshi?What are sacred geometries?The 8 Clair sensesWhat is Parts Work?10 ways to connect with your higher selfAge regression hypnotherapyWays to connect with Masako:Let's meditate together on InsightTimer!Why not meditate? FB Groupwhynotmeditate.podcast IGmasakozawa_coaching IGWebsiteSupport the show

On the latest episode of ‘New Classical Tracks,' Grammy-winning composer Michael Daugherty talks about his latest album, ‘Blue Electra,' which explores the triumphs and tragedies of flight, and features violinist Anne Akiko Meyers. Listen now with host Julie Amacher!

Comment on this episode by going to KDramaChat.comToday, we'll be discussing Episode 4 of When Life Gives You Tangerines, the hit K Drama on Netflix starring Park Bo-gum as Gwan-sik, Kim So-hyun as Ae-sun, and featuring a deeply emotional story about family, hardship, love, and resilience. We discuss:The song featured during the recap: "Name" by Kwak Jin-eon, a tender ballad reflecting the enduring love between Ae-sun and Gwan-sik.Joanna's magical trip to Japan, including cherry blossoms, sushi, Enoshima Island, and meeting the amazing Akiko in Shinjuku Gyoen.How the lyrics of "Name" perfectly capture the decades-long bond between Ae-sun and Gwan-sik.The brutal reality of Ae-sun's early married life, especially her abuse by her in-laws due to not producing a son.The significance of 108 prostrations in Korean Buddhism and the intense societal pressure on wives to bear sons.South Korea's declining fertility rate, from 6 children per woman in the 1960s to close to the lowest in the world today.The heartbreaking and symbolic moment when Ae-sun flips the table to prevent her daughter from becoming a haenyeo.The shocking revelation that Gwan-sik is being physically abused by his boss — the man Ae-sun almost married!Ae-sun's fierce loyalty and love for Gwan-sik, including confronting his abuser in front of the entire village.The evolving dynamic between Ae-sun and her daughter Geum Myeong in 1994, especially around class, shoes, and emotional validation.Gwan-sik and Ae-sun's intimate physical and emotional connection, even decades into their marriage.The symbolism of sugar, kimjang, and daily packed lunches in expressing affection, social rules, and hardship.The beautiful theme of quiet sacrifice — how both Ae-sun and Gwan-sik shield each other from their respective pains.The significance of the episode's title, “The Blazing Summer Sunshine,” as a metaphor for both oppressive hardship and the radiant love that sustained them.A spotlight on Park Bo-gum: his acting and musical background, clean-cut reputation, and his return to dramas after military service.Next week, we'll recap and analyze Episode 5 of When Life Gives You Tangerines, and talk about the real-life couple that inspired this drama — or so the internet says!ReferencesKorean Beliefs: 5 Foods Believed to Repel Evil Spirits – Seoulbox.Prostrating as a Part of Buddhist Practice - Buddhistdoor Global.Did South Korea's Population Policy Work Too Well? | PRBPark Bo-gum - WikipediaKwak Jin Eon on Spotify

Comment on this episode by going to KDramaChat.comToday, we'll be discussing Episode 3 of When Life Gives You Tangerines, the hit K Drama on Netflix starring IU as Ae Sun and Park Bo Gum as Gwan Sik. We discuss:The song featured during the recap: “Neoyeong Nayeong” by Ahn Eun Kyung and Eunyong Sim, a haunting blend of traditional and modern sound, sung in the Jeju dialect and about young love.How the show is beautifully infused with Jeju-specific language, culture, and music.Our heartfelt shoutouts to listeners, including Ellen's birthday and Joanna's meetup with Akiko in Tokyo.The folk tale of the honest woodcutter and its metaphorical significance for Ae Sun's comparison of Gwan Sik to a steel axe.The heartbreak of Ae Sun pushing Gwan Sik away—not out of lack of love, but to set him free.The injustice of Ae Sun's expulsion from school while Gwan Sik only gets suspended, a commentary on gender and social status.Gwan Sik melting down his doljanchi rings to make a ring for Ae Sun—rings full of cultural symbolism and maternal sentiment.The chilling portrayal of Ae Sun's potential suitor, a widower looking more for unpaid labor than a partner.Gwan Sik's dramatic decision to swim back to Ae Sun after hearing her cries at the harbor—an epic open water swim of love and determination.Our leads' emotional reunion, wedding, and the symbolism of Ae Sun's wide-brimmed hat and new ring.The support of the haenyeos and their reference to the Cowherd and Weaver Girl folktale, a beautiful metaphor for star-crossed love.The reveal that Ae Sun was pregnant from their night in Busan, explaining the early birth of their daughter and the "conception dream" of Gwan sik's grandmother.The bittersweet final scene, where Ae Sun and Gwan Sik acknowledge that while they gave up dreams of poetry and athletic stardom, they have no regrets about choosing each other.Our deep dive into IU's stellar career as a singer, actress, and philanthropist—highlighting why she's beloved by so many around the world.Next week, we'll recap and analyze Episode 4 of When Life Gives You Tangerines and talk about the handsome and talented Park Bo Gum!ReferencesKnown as the “Poet of Flag,” Yu Chi-hwanFolk songs of JejuThe Honest WoodcutterThe Weaver and the Cow Herdsman: A tale of two lovers whose deep affection triumphed over loneliness

リスナーアンケートをしています。ご協力お願いいします！We are conducting a listener survey. We appreciate your cooperation!https://jp.surveymonkey.com/r/FFRT7NN⁠無料のスクリプトThe script for free!⁠⁠⁠⁠⁠https://buymeacoffee.com/mikasensei/extras⁠⁠⁠⁠⁠気に入ったら応援してね⁠⁠⁠⁠⁠buymeacoffee.com/mikasensei⁠⁠⁠⁠⁠YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@Mikasensei17⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mikasensei17/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠4月にイベントをします！神戸のバーで８０年代アイドル中山美穂の音楽を流します。もしよかったら遊びに来てください！City popが好きな人は楽しめるかもしれません。I'm hosting an event in April!We'll be playing 80s idol Miho Nakayama's music at a bar in Kobe.If you'd like, please come and join us!People who like city pop might enjoy it.4月26日（土） 　Open | 3:00 pm Start | 7:00 pmPlace | Food BarENDSAdress | 〒650-0012神戸市中央区北長狭通2丁目10-1 天天ビル３FTEL | 09031194833https://maps.app.goo.gl/PNT5dFyWGWMewGAo8

Fluent Fiction - Japanese: Unveiling Secrets: The Bamboo Grove's Hidden Legacy Find the full episode transcript, vocabulary words, and more:fluentfiction.com/ja/episode/2025-03-21-22-34-02-ja Story Transcript:Ja: 春の訪れとともに、嵐山の竹林には穏やかな風が吹いていました。En: With the arrival of spring, a gentle breeze blew through the bamboo grove in Arashiyama.Ja: ここはカナが心の安らぎを求める場所です。En: This is the place where Kana seeks peace of mind.Ja: 竹の茎が太陽の光を受けて鮮やかに輝き、鳥たちのさえずりが静寂をやさしく破ります。En: The bamboo stalks shone brightly as they caught the sunlight, and the birds' chirping gently broke the silence.Ja: 春分の日。En: The vernal equinox day.Ja: 今日は特別な日でした。En: Today was a special day.Ja: カナはいつもの場所に座り、深呼吸をして心を落ち着けます。En: Kana sat in her usual spot, took a deep breath, and calmed her mind.Ja: しかし、そのとき、地面に何かが見えました。En: However, at that moment, she noticed something on the ground.Ja: 茶色い小さな封筒です。En: It was a small brown envelope.Ja: 封筒は少し古びていましたが、カナは興味をそそられてそれを手に取ります。En: The envelope was slightly old, but Kana was intrigued and picked it up.Ja: 封筒を開けると、中には短いメッセージが。En: When she opened the envelope, there was a short message inside.Ja: 「家族の過去と未来を知りたければ、竹林の秘密を探れ」と書かれていました。En: It read, "If you want to know the past and future of your family, seek the secret of the bamboo grove."Ja: 心がざわつきます。En: Her heart was stirred.Ja: カナはこのメッセージが何を意味するか知りたくなりました。En: Kana became curious about what this message could mean.Ja: それでカナは幼なじみのハルトを訪ねました。En: So Kana visited her childhood friend, Haruto.Ja: ハルトは好奇心旺盛な性格で、ことごとく新しい冒険を求める男の子です。En: Haruto is a boy with a curious personality, always seeking new adventures.Ja: 「ねえ、ハルト。この手紙、どう思う？」カナはハルトに封筒を差し出しながら言いました。En: "Hey, Haruto. What do you think of this letter?" Kana asked as she handed him the envelope.Ja: ハルトはそれをじっくり読み、「これは冒険の始まりかもね。まず、この秘密を探ろう」と言いました。En: Haruto read it carefully and said, "This might be the start of an adventure. Let's first uncover this secret."Ja: それで二人は竹林をもっと調べることにしました。En: With that, the two decided to investigate the bamboo grove further.Ja: 調査を進めるうちに、竹の茂みの中に古い日記を見つけます。En: As they continued their investigation, they found an old diary among the bamboo thickets.Ja: 日記はカナの家族について詳しく書かれていました。En: The diary contained detailed information about Kana's family.Ja: 長い間隠されていた家宝が、アキコという近所の芸術家の家に関係していることがわかります。En: It turned out that a long-hidden family heirloom was connected to the house of a nearby artist named Akiko.Ja: アキコは秘密主義で有名ですが、絵を通した独特の表現力を持っています。En: Akiko is known for being secretive but possesses a unique form of expression through her paintings.Ja: 彼女の助けを借りて、カナは日記の謎を解く手がかりを得ることができました。En: With her help, Kana was able to find clues to solve the mystery of the diary.Ja: アキコは冷静に言いました。「心を閉ざさずに、過去を受け入れることが大切よ。」En: Akiko calmly said, "It's important to keep your heart open and accept the past."Ja: カナは両親と向き合い、日記のことを話す決心をしました。En: Kana resolved to face her parents and discuss the diary.Ja: 思いもよらないことに、両親は心を開き、家族の歴史について初めて話しました。En: To her surprise, her parents opened up and spoke about their family's history for the first time.Ja: 「家宝はただの美しいものではない。絆を描いた私たちの歴史なのだ」と。En: "The heirloom is not just a beautiful object. It's the history of our bonds," they said.Ja: その日、カナは自分の過去を受け入れ、家族と再び絆を深めることができました。En: That day, Kana was able to accept her past and strengthen her bonds with her family once again.Ja: 自信を持つ彼女は、未来をしっかりと見据えて歩き始めました。En: With newfound confidence, she began to walk forward, firmly looking towards the future.Ja: 竹が春風に揺れるように、カナの心もまた新しい一歩を踏み出しました。En: Just as the bamboo sways in the spring breeze, Kana's heart took a new step forward. Vocabulary Words:arrival: 訪れgrove: 竹林gentle: 穏やかなbreeze: 風whispered: ささやいたchirping: さえずりequivalent: 対等のintrigued: 興味をそそられるenvelope: 封筒stirred: ざわつくadventure: 冒険investigate: 調べるdiary: 日記heirloom: 家宝expression: 表現clue: 手がかりmystery: 謎resolved: 決心をしましたbonds: 絆confidence: 自信purpose: 目的confidence: 自信strengthen: 強化するpossession: 所持calmly: 冷静にaccept: 受け入れるhistory: 歴史silence: 静寂curious: 好奇心旺盛なuncover: 探る

Fluent Fiction - Japanese: Blossoming Memories: A Springtime Tribute in Kyoto Find the full episode transcript, vocabulary words, and more:fluentfiction.com/ja/episode/2025-03-12-22-34-00-ja Story Transcript:Ja: 春の朝でした。En: It was a spring morning.Ja: 京都の小さなゲートコミュニティには、美しい桜が咲き誇り、街道を静かに彩りました。En: In a small geeto komyuniti in Kyoto, beautiful sakura bloomed in full glory, quietly coloring the streets.Ja: しかし、春の喜びの中に、ハルトとアキコの心には陰りがありました。En: However, amidst the joys of spring, there was a shadow in the hearts of Haruto and Akiko.Ja: 二人は、愛する祖母の亡くなったことをまだ受け入れられずにいました。En: They still couldn't accept the passing of their beloved grandmother.Ja: ハルトは実用的な兄でしたが、祖母の思い出を大切にしたいと考えていました。En: Haruto, the practical-minded brother, wanted to cherish their grandmother's memories.Ja: 一方で、妹のアキコは物を捨てることを恐れ、全てを残しておきたいと思っていました。En: On the other hand, his sister Akiko was afraid of throwing things away, wanting to keep everything.Ja: 「アキコ、もっと現実的に考えよう。祖母の思い出を大切にするためのスペースが欲しい。」ハルトが言いました。En: "Akiko, let's think more realistically. I want space to properly cherish grandma's memories," Haruto said.Ja: 「でも、私にとって全てが大切なの。物を手放すと、祖母のことを忘れてしまいそうで怖い。」アキコは泣きそうになりました。En: "But everything is precious to me. I'm scared that if I let go of things, I'll forget about grandma," Akiko nearly cried.Ja: その頃、コミュニティの人々はハナミのお祝いの準備を進めていました。En: Meanwhile, people in the community were preparing for a hanami celebration.Ja: 二人も参加するようにと勧められ、さらに心が乱れました。En: They were encouraged to participate and felt even more conflicted.Ja: ハナミの日、二人は祖母の写真と大切な品を持って庭に出ました。En: On the day of hanami, the two brought their grandmother's photo and cherished items into the garden.Ja: 桜の花びらが舞う中で、ハルトはアキコに言いました。「大事なのは、心の中にある思い出だよ。En: Among the fluttering sakura petals, Haruto said to Akiko, "What's important are the memories in our hearts.Ja: 物はその心を支えるものでしかない。」En: The items merely support that heart."Ja: アキコはしばらく言葉が出ませんでしたが、やがて小さくうなずきました。En: Akiko was speechless for a moment but then nodded slightly.Ja: 「そうね、ハルト。ありがとう。祖母がそばにいてくれるって思うために、少しでも共有できる場所を作ろう。」En: "Yes, Haruto. Thank you. To feel grandma is with us, let's create even a small shared space."Ja: 二人は祖母の小さなメモリアルスペースを庭に作り、祖母の好きだった花や、いつも使っていた茶碗をそこに置きました。En: The two created a small memorial space for their grandmother in the garden, placing her favorite flowers and the teacup she used often there.Ja: これが新しい伝統になると分かり、心に温かさが広がりました。En: Understanding that this would become a new tradition, warmth spread in their hearts.Ja: 桜の下で二人は肩を並べて座りました。En: Under the sakura tree, they sat shoulder to shoulder.Ja: 「桜の花びらを見上げると、まるで祖母が微笑んでいるようだね。」とハルトが言いました。En: "Looking up at the sakura petals, it's like grandma is smiling at us," Haruto said.Ja: 「うん、これから毎年、この場所で祖母と過ごすのね。」アキコも微笑みました。En: "Yes, from now on, we'll spend this time with grandma every year in this place," Akiko smiled too.Ja: 二人は静かに、しかし確実に、互いの心をつなぎ、そして祖母を偲びました。En: Quietly, yet surely, they connected their hearts and remembered their grandmother.Ja: ハナミの明るさと共に、彼らは前向きに未来へ進む力を感じていました。En: Along with the brightness of hanami, they felt the strength to move forward positively toward the future.Ja: 春風が彼らの涙をそっと吹き飛ばし、彼らは新しい伝統を胸に刻みました。En: The spring breeze gently blew away their tears, and they engraved the new tradition in their hearts. Vocabulary Words:spring: 春community: コミュニティbloomed: 咲き誇りglory: 栄光amidst: 中にcherish: 大切にrealistically: 現実的にscared: 怖いencouraged: 勧められconflicted: 葛藤したfluttering: 舞うmerely: でしかないspeechless: 言葉が出ませんshared: 共有memorial: メモリアルtradition: 伝統warmth: 温かさblossoms: 花びらengraved: 刻みましたpositively: 前向きにfluttered: 舞うbeloved: 愛するhearts: 心properly: 適切にafraid: 怖いitems: 品slightly: 小さくspace: スペースsmiling: 微笑んでfuture: 未来

Our guest is Alexander Nicolau who is the founder of Mandaracha https://www.mandaracha.com/ in Kyoto, which opened in 2019.  Originally from France, Alex fell in love with Japanese tea while he was working in the fields of food technology and open innovation.Mandaracha is a very special place where you can find a variety of Japanese tea, which Alex selected by visiting and meeting with each producer.  You can also enjoy a tea ceremony and have other cultural experiences, such as a Shamisen guitar performance and a Rakugo comedy show.In this episode, we will discuss how Alex got into Japanese tea, why he loves Japanese tea so much, the classic and new types of Japanese tea Alex recommends, the rapidly changing tea market, the future of the Japanese tea industry and much, much more!!!Social Handles: IG  kyoto_mandarachahttps://www.facebook.com/MANDARACHAhttps://www.linkedin.com/company/mandaracha/

In this Fuck Yeah Friday episode, Lesley shares an inspiring story about Japan's Café of Mistaken Orders, a big win from a member's Pilates business, and how she turned a long layover into an exciting adventure. Tune in for a dose of motivation and a reminder to ask yourself: Why not?If you have any questions about this episode or want to get some of the resources we mentioned, head over to LesleyLogan.co/podcast. If you have any comments or questions about the Be It pod shoot us a message at beit@lesleylogan.co. And as always, if you're enjoying the show please share it with someone who you think would enjoy it as well. It is your continued support that will help us continue to help others. Thank you so much! Never miss another show by subscribing at LesleyLogan.co/subscribe.In this episode you will learn about:How one woman's vision is reshaping dementia care in JapanA Pilates instructor's win that proves consistency pays offHow Lesley turned an inconvenient layover into an exciting adventureA simple but powerful mindset shift: Why not?Episode References/Links:Cafe of Mistaken Orders - https://www.instagram.com/aijamayrock/reel/DBEII-6POmL/ If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser or Castbox. DEALS! DEALS! DEALS! DEALS!Check out all our Preferred Vendors & Special Deals from Clair Sparrow, Sensate, Lyfefuel BeeKeeper's Naturals, Sauna Space, HigherDose, AG1 and ToeSox Be in the know with all the workshops at OPCBe It Till You See It Podcast SurveyBe a part of Lesley's Pilates MentorshipFREE Ditching Busy Webinar Resources:Watch the Be It Till You See It podcast on YouTube!Lesley Logan websiteBe It Till You See It PodcastOnline Pilates Classes by Lesley LoganOnline Pilates Classes by Lesley Logan on YouTubeProfitable Pilates Follow Us on Social Media:InstagramThe Be It Till You See It Podcast YouTube channelFacebookLinkedInThe OPC YouTube Channel Episode Transcript:Lesley Logan 0:00  It's Fuck Yeah Friday.Brad Crowell 0:01  Fuck yeah. Lesley Logan 0:05  Welcome to the Be It Till You See It podcast where we talk about taking messy action, knowing that perfect is boring. I'm Lesley Logan, Pilates instructor and fitness business coach. I've trained thousands of people around the world and the number one thing I see stopping people from achieving anything is self-doubt. My friends, action brings clarity and it's the antidote to fear. Each week, my guest will bring bold, executable, intrinsic and targeted steps that you can use to put yourself first and Be It Till You See It. It's a practice, not a perfect. Let's get started.Lesley Logan 0:48  Hello. Be It babe. Oh my goodness. Hi. It is your FYF. It is time for us to celebrate some wins and be inspired by people's wins and what is possible in this world and with each other. And I'm just so excited to share with you what I've just discovered. So there's this place in Japan, and it's called the Cafe of Mistaken Orders. Okay, have you heard of this? So, a woman named Akiko created a cafe where her father, with his dementia, could work. And so the place has people who have dementia. You have to have dementia to work there, and then there's some volunteers, and you work two hours a day, and you maybe bring the correct order to someone, maybe you never bring an order, maybe you sit down and talk to people instead. But at any rate, the goal of the cafe is to help people with dementia stay connected to society, which has proven to slow down dementia. And because Japan is this aging country like they have a lot of elderly people, they've been spending a lot of time trying to figure out how to keep the people with dementia connected. They have a lot of dementia cases, and now they have 8000 dementia cafes in Japan. So there's 8000 places where people with dementia are working, and it's just really freaking cool. So, thank you. Asia may rock on Instagram for highlighting Akiko and the Mistaken Order cafe and what this is doing, because I really like it. And I don't know if you've heard, but one in six Americans will have dementia, and if you're a woman, your rates go up, I guess, estrogen stuff, blah, blah, blah. At any rate, I think this is really amazing, and I'm really impressed with people on the things that they can do on this planet with not a lot. What a great idea. You know, sometimes we're like, how do I change the world? Well, how do you change a person's life that you know, and you'd be surprised how that's a domino effect of changing the world, like she's changing a country with this. I'm obsessed. Thank you so much. Lesley Logan 2:36  Okay, so now a win. We gotta celebrate more wins. So Akiko is winning in Japan with that. Kelly Nyhan out of Chicago, who actually, I have, the reason I picked her win is because I'm actually about to see her in a couple of days in Cambodia. So here it is. After two years of working with two different clients, they have finally decided to commit to a permanent day and time per week with the expectation to reschedule when they miss. I highly encourage versus enforced, but I think that my elevated teaching of the work and my intention at around working with them, perhaps has made the difference. I also am a high touch type of communicator, educating, motivating and celebrating along the way in the studio, but also through email, PocketSuite, her scheduling tool, and on social media. So yay. I'm feeling really great about it, and now I can count on the income each week. I also have a boundary, mostly in my head, that I don't work with people unless their intention is to commit to one time per week, no here and there, two times per month, et cetera. Just no. That sounds like a better fit for class for them. Kelly, I love your win. I love that it's kind of a unspoken rule. I love that you have these people who, now, after listening to you all this time, finally feel the importance. You did that. And also, you didn't stop reminding them of this possibility, right? Like you just kept doing it. You've just kept putting yourself out there. You kept being yourself more importantly, and that is so beautiful. So thank you so much for sharing that with us, and what an amazing win. And yes, now you can count on that income, and I'm so excited to celebrate in Cambodia with you. Lesley Logan 4:01  So, my win. Well, Brad and my win. So, okay. Traveling to Cambodia is not always the easiest thing. There's not always a lot of options for us. And I have some airlines I love and some airlines I refuse to fly on. So at any rate, we had the option of having like, six hour layovers in the middle of the night in Singapore. So shorter travel, but like, $300 more a person, okay? Or we could take this really weird flight option, which would have given us 13 hours overnight in Singapore each way. And I decided, not only does that, not to save the money, but I did like the price. I was like, yes, finally, we're under $1,000 to fly to Cambodia, yes. But really, I've always wanted to see the Singapore skyline. I've just always wanted to see it. Just so excited to see it. And so I chose that one because now both Brad and I have an evening to go on a date in Singapore on the way to Cambodia and all the way home. And I share that with you because I think sometimes we don't travel or we don't do things. We're like, oh the time commitment, oh the thing. But what if you could find a silver lining in what is going on with that oh-thing and take advantage of it. So I am totally taking advantage of these ridiculous layovers where I get to leave the airport and see Singapore. I get to see it. I'm so, so excited. So it's just gonna be it's gonna be beautiful. I'm gonna post pictures. I'm calling this a win. 13-hour layover. That's a win. It's not funny. So maybe you can also have a 13-hour layover. Where would you lay over for 13 hours? I want to know. Lesley Logan 5:38  All right, your mantra. Why not? Why not? How timely I just threw this from. How timely. Why not? 13 hours in Singapore. Why not? Why not? Why not start a book club? Why not go to dinner by yourself? Why not? Why not? What is your why not that you're going to use this mantra on this weekend. I want to know. Please share your wins with me. I love sharing them in. Send your questions into the Be It Pod, we answer them on the recap episodes. Share our interviews or our recap episodes, or this with a friend who needs it, needs inspiration. Now also, by the way, I've got to figure out how to go to Japan, because I do want to go to the dementia cafe. I mean, I looked at the menu. I can't have anything on it, but the tea. And I really love tea, but, you know, they probably won't even bring it to me anyway, so it doesn't really matter. I just want to experience what this cafe, the Cafe of Mistaken Orders. Like, how perfectly imperfect is that? Beautiful. All right, loves, take care of yourself out there. Okay? You are the only person who could do it to do the way that you do it. You're it. And you're probably working yourself really, really hard. So what breaks can you take? What things can you do to support yourself? Yeah, and ask yourself, why not? All right, until next time loves, Be It Till You See It. Lesley Logan 6:51  That's all I got for this episode of the Be It Till You See It Podcast. One thing that would help both myself and future listeners is for you to rate the show and leave a review and follow or subscribe for free wherever you listen to your podcast. Also, make sure to introduce yourself over at the Be It Pod on Instagram. I would love to know more about you. Share this episode with whoever you think needs to hear it. Help us and others Be It Till You See It. Have an awesome day. Be It Till You See It is a production of The Bloom Podcast Network. If you want to leave us a message or a question that we might read on another episode, you can text us at +1-310-905-5534 or send a DM on Instagram @BeItPod.Brad Crowell 7:21  It's written, filmed, and recorded by your host, Lesley Logan, and me, Brad Crowell.Lesley Logan 7:27  It is transcribed, produced and edited by the epic team at Disenyo.co.Brad Crowell 7:31  Our theme music is by Ali at Apex Production Music and our branding by designer and artist, Gianfranco Cioffi.Lesley Logan 7:38  Special thanks to Melissa Solomon for creating our visuals.Brad Crowell 7:43  Also to Angelina Herico for adding all of our content to our website. And finally to Meridith Root for keeping us all on point and on time.Support this podcast at — https://redcircle.com/be-it-till-you-see-it/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Comment on this episode by going to KDramaChat.comToday, we'll be discussing Episode 11 of See You In My 19th Life, the hit K Drama on Netflix starring Shin Hye-sun as Ban Ji-eum, Ahn Bo-hyun as Moon Seo-ha, Ha Yoon-kyung as Yoon Cho-won, Ahn Dong-goo as Ha Do-yoon, and Cha Chung Hwa as Kim Ae-gyeong. We discuss:The songs featured during the recap: Shaman by HEO, What by Sol Han, and I'll Embrace Your Past by Ahn Bo-hyun. Shaman is eerie and haunting, while What adds a frantic, comic energy. I'll Embrace Your Past is especially meaningful as Seo-ha accepts Ji-eum's past lives and vows to stay by her side.How Ji-eum finally discovers the truth about her first life—it wasn't Seo-ha's past self, Master Han Ya, who killed her sister Seol, but Master Cheon Un, Kang Min Gi's past self.The heartbreaking revelation that Ji-eum herself placed the curse to remember her past lives, fueled by rage and grief after Seol's death.Kang Min Gi's role as a guide for those trapped in the cycle of reincarnation. He helps others find peace, yet remains stuck himself, as he hasn't encountered the person who triggered his own memories.The historical context of untouchable classes—the Baekjeong in Korea, Burakumin in Japan, and Dalits in IndiaThe cultural significance of shaman bells in Korean rituals, symbolizing the "opening of the gate of words" to invite spirits into the ritual space.Ji-eum's emotional turmoil upon realizing that Seo-ha didn't betray her in her 1st life. Instead, Master Han Ya tried to protect her, and Ji-eum's misunderstanding led her to attack Seo-ha in this life.The complicated dynamic between Kang Min Gi and Ji-eum. He wants her to become "normal" by fully remembering her first life, but his own cycle remains unbroken.The unraveling of the cover-up around the car accident that killed Yoon Ju-won. Chairman Moon, Seo-ha's father, hid the truth to protect Seo-ha and avoid scandal, while Director Lee, Seo-ha's uncle, lived for 24 years under the weight of his guilt.Ha Do Yoon's emotional struggle over his feelings for Yoon Cho-won. Encouraged by both Ji-eum and Seo-ha, he's urged to follow his heart despite the social barriers.The touching parallel between Seo-ha's note to Ji-eum—"In bad times, remember the happy moments. I'm by your side"—and Ji-eum's earlier words under the cherry blossoms.The geographic lesson of the week—Kottayam, India—a city known as the "city of letters" for its publishing industry.Fun listener interactions: Tina's blog comment listing Ji-eum's known past lives, Akiko and Joanna planning a cherry blossom meet-up in Shinjuku Gyoen Park, and new listeners like Irma finding the podcast after Queen of Tears.A special announcement: After the final episode, Joanna and Sung Hee will do a one-off episode discussing When The Phone Rings, joined by Ernabel Demillo. They'll dive into the drama's wild plot twists and controversial ending.Tease for Season 11—a new show has almost been decided, but listeners still have time to sway the choice by commenting on the blog or Instagram.Next week, we'll recap and analyze Episode 12 of See You In My 19th Life and officially announce our pick for Season 11!ReferencesIn South Korea, shamans are shunned — and reveredDalits in India

And my guest today is Toshio Shinko who is the fifth-generation owner of Marushin Honke in Wakayama Prefecture, Japan.  The company was founded in 1881 and since then, it has produced high-quality traditional Japanese food products, such as miso and soy sauce.  In 2002, in addition to managing Marushin Honke, Toshio founded the new company Yuasa Shoyu, or Yuasa Soy Sauce https://www.yuasasyouyu.co.jp/yuasa_gb_front.html in English to pursue the highest quality of soy sauce that reflects the family tradition.Preserving tradition is hard and even harder is to keep it fresh in response to the fast-changing environments.  Toshio has been very successful in doing so and a great example is his innovative idea of making soy sauce in Bordeaux, France https://www.yuasasyouyu.co.jp/yuasa_gb.html in collaboration with the well-established Grand Cru winery Chateau Coutet in Saint Emilion.In this episode, we will discuss how Toshio's company produces premium soy sauce with wood barrels, which is rare these days, how he came up with the idea of making soy sauce in the French wine country, why the French winery wants to make soy sauce with Toshio, how his Bordeaux-made soy sauce is different, why French chefs love using it and much, much more!!!Here is a fabulous YouTube video, that captures how Toshio makes soy sauce with the French partner Adrien David Beaulieu, the owner of Chateau Coutet and his team.  https://www.marushinhonke.com/f/marushin(Scroll further down and click on “We want to spread Yuasa soy sauce to France!”)Here are some of the restaurants that uses Toshi's Bordeaux-made soy sauce:·       Maison nouvelle, Etchebest　https://maison-nouvelle.fr/　·       Lalique, Lafaurie Peyraguey Schilling　　https://www.lafauriepeyragueylalique.com/en/michelin-starred-chef-jerome-schilling-unveils-his-autumn-menu/　·       Skiff Club, Stéphane Carrade　　https://haaitza.com/les-restaurants-cafe-bar-brasserie-restaurant-etoile-arcachon/　·       Le Prince Noir, Vivien Durand　　https://leprincenoir-restaurant.fr/　·       L opidom etoilé Fondette　　https://www.lopidom.fr/fr/　

Kindermann, Kim www.deutschlandfunkkultur.de, Lesart

Kindermann, Kim www.deutschlandfunkkultur.de, Lesart

Kindermann, Kim www.deutschlandfunkkultur.de, Lesart

Our guest is Emily Yuen who is the executive chef at Lingo https://www.lingobk.com/, a unique Japanese American restaurant in Brooklyn, New York.Emily has an impressive culinary background.  She worked at top French restaurants in the world, including Le Gavroche in London, DB Bistro in Singapore and Boulud Sud in New York. She also studied Japanese cuisine at the legendary Shojin restaurant Kajitsu and served as the executive chef at Bessou in New York.At Lingo, with her global knowledge and experience, Emily offers original dishes, such as Hokkaido-style braised beef curry pie and Donabe hotpot with wild mushroom and koji butter.In this episode, we will discuss how Emily's culinary focus shifted from French to Japanese, the essence of Japanese cuisine that she wants to share with her guests, how she naturally merges French techniques and Japanese flavors, the importance of Japanese home cooking in her menu development and much, much more!!!

Fluent Fiction - Japanese: Love in Kyoto: A Startup Story Amidst Falling Snow Find the full episode transcript, vocabulary words, and more:fluentfiction.com/ja/episode/2025-02-11-23-34-02-ja Story Transcript:Ja: 真冬の京都の街は、雪が静かに降り積もる朝でした。En: The streets of Kyoto on a midwinter morning were covered in quietly falling snow.Ja: あたりは白く染まり、空気は冷たく澄んでいました。En: The surroundings were painted white, and the air was cold and crisp.Ja: しかし、その寒さを打ち破るように、起業家たちの活気に満ちた建物がありました。En: However, standing in defiance of the chill was a building bustling with the energy of entrepreneurs.Ja: それが、スタートアップインキュベーターです。En: It was a startup incubator.Ja: ヒロシは熱心な起業家で、毎日ここで新しい技術のアイデアを磨いていました。En: Hiroshi was a passionate entrepreneur who polished his ideas for new technology here every day.Ja: 彼は内向的な性格ですが、成功への強い情熱を持っていました。En: He had an introverted personality but possessed a strong drive for success.Ja: 少し人と距離を置くことが多かったのです。En: He often kept a bit of distance from people.Ja: 一方、アキコは創造的でマーケティングの才能を持つ明るい女性でした。En: On the other hand, Akiko was a bright woman with creative and marketing talents.Ja: 彼女は人とのつながりを大切にし、新しい友人を作ることが好きでした。En: She valued connections with others and enjoyed making new friends.Ja: 彼らはこのインキュベーターで初めて出会いました。En: They met for the first time at this incubator.Ja: アキコのおおらかさとユーモアに、ヒロシは少しずつ心を開いていきました。En: Hiroshi gradually began to open up to Akiko's easygoing nature and humor.Ja: そして、冬のある日、ヒロシは勇気を出してアキコとのプロジェクトのために協力しようと決めました。En: Then, one winter day, Hiroshi mustered the courage to propose collaborating on a project with Akiko.Ja: 「アキコ、一緒にプロジェクトをしませんか？」と、彼は言いました。En: "Akiko, would you like to do a project together?" he asked.Ja: アキコはうれしそうに微笑み、こう答えました。「もちろん、楽しみだね！」En: Akiko smiled happily and replied, "Of course, I'm looking forward to it!"Ja: 彼らは一緒に新しいテクノロジーとデザインのアイデアを結びつけて、革新的なビジネスプランを作り始めました。En: Together, they started connecting new technology and design ideas to create an innovative business plan.Ja: 時間が経つにつれて、ヒロシは彼女の存在がどれほど彼にとって大切かを感じ始めました。En: As time passed, Hiroshi began to realize how important her presence was to him.Ja: しかし、ヒロシの頭の中には一つの不安がありました。En: However, he had one concern on his mind.Ja: 「仕事と恋愛、両立できるのだろうか？」En: "Can I balance work and romance?"Ja: バレンタインデーが近づく頃、インキュベーターで大きなピッチコンペティションが行われることになりました。En: As Valentine's Day approached, a major pitch competition was scheduled to take place at the incubator.Ja: ヒロシとアキコは、彼らのアイデアを披露する準備を始めました。En: Hiroshi and Akiko began preparing to showcase their ideas.Ja: その日、彼らは精一杯のプレゼンテーションを行いました。En: On that day, they gave their best presentation.Ja: ヒロシはアキコを見ると、彼女の勇気と洞察力に深く感謝し、同時に彼女への感情を再確認しました。En: Looking at Akiko, Hiroshi deeply appreciated her courage and insight and, at the same time, reaffirmed his feelings for her.Ja: 結果は予想以上に良く、彼らのチームは勝利を手にしました。En: The results were better than expected, and their team claimed victory.Ja: 緊張感から解放され、二人は喜びを分かち合い、外の雪が降りしきる中で暖かなカフェに入りました。En: Released from the tension, the two shared their joy and entered a warm café as the snow continued to fall outside.Ja: そこでヒロシは、やっと自分の心の中を明かしました。En: It was there that Hiroshi finally revealed his feelings.Ja: 「アキコ、君と一緒にいると、本当に楽しい。En: "Akiko, being with you is really fun.Ja: これからはもっと、一緒に色々なことを経験したい。」En: From now on, I want to experience many things together."Ja: アキコは驚いた表情から微笑みへと変わり、静かに言いました。「私も同じ気持ちだよ。En: Akiko's surprised expression turned into a smile, and she quietly said, "I feel the same way.Ja: このまま一緒に、仕事も楽しみも、すべて分かち合おう。」En: Let's continue to share everything, both work and enjoyment, together."Ja: こうして、冷たい冬に包まれた京都の街で、ヒロシとアキコは新しいスタートを切りました。En: Thus, Hiroshi and Akiko embarked on a new journey in the snow-covered streets of Kyoto.Ja: 彼らは共に成長し、仕事と個人のバランスを見つける旅を始めました。En: They began a journey to grow together and find a balance between work and personal life.Ja: その先には、まだ見ぬ未来が待っていましたが、その一歩を共に踏み出す決意を固めたのです。En: Though an unpredictable future awaited them, they were determined to take that step forward together.Ja: 彼らを包むインキュベーターの温かい明かりは、静かに二人を見守っていました。En: The warm light of the incubator enveloped them, watching over them quietly. Vocabulary Words:midwinter: 真冬surroundings: あたりdefiance: 打ち破るbustling: 活気に満ちたincubator: インキュベーターentrepreneur: 起業家introverted: 内向的drive: 情熱distance: 距離creative: 創造的talents: 才能connections: つながりeasygoing: おおらかさmustered: 勇気を出してcollaborating: 協力innovative: 革新的realize: 感じ始めましたconcern: 不安balance: 両立pitch: ピッチscheduled: 行われるshowcase: 披露するappreciated: 感謝しinsight: 洞察力reaffirmed: 再確認しましたvictory: 勝利tension: 緊張感revealed: 明かしましたembarked: 新しいスタートを切りましたunpredictable: まだ見ぬ

Our guest is Kakuho Aoe https://www.instagram.com/kakuhoaoe_nakamichi0316/ who is the chief Buddhist priest of the Ryokusenji Temple in Asakusa, Tokyo.Kakuho Aoe joins me to discuss why food is important in the Buddhist practice and beyond, why the Buddhist diet called Shojin Ryori is great diet for vegan, vegetarian and sustainable-minded people regardless of their religion, the eye-opening dinner events “Kuayami Gohan” (Dining in the Dark) and much, much more!!!

「More Clients More Authenticity」私の新しいマスタークラスで、 理想のお客様が自然と集まるビジネス基盤を一緒に作りませんか？ 無料登録はこちら ✨ このマスタークラスで学べること✨ このマスタークラスでは、あなたの価値を目に見える形で届け、理想のクライアントと深い信頼関係を築くための「7つのレッスン」をご紹介します。 オーセンティックなブランドの土台づくり – あなたらしさが反映されたブランドで、理想のクライアントを自然に引き寄せます。 心に響くメッセージ作り – 個性＆専門性を自然に伝える、共感を呼ぶメッセージの作成方法。 持続可能なクライアント集客の戦略 – プレッシャーを感じさせず、安心して信頼関係を育む集客方法。 自信と自己価値の強化 – 自分の価値をしっかり認識し、安定した土台からプロとしての在り方を磨きます。 セールスの失敗回避法 – よくある失敗を避け、クライアントに安心してもらえるセールスプロセスを学びます。 Chat GPT+ヒューマンデザインがどのように可能性を広げるか – あなたの個性や強みを最大限に引き出し、ビジネスに自然に活かし、効果的に実績を伸ばしていく方法を学びます。 2025年のオンラインビジネス＋コーチング業界のアップデート – 次の時代に向けて、あなたのビジネスを進化させるための最新トレンドと戦略を理解し、未来の市場に合わせたアプローチを学びます。 「気づかれない存在から、求められる存在へ」。このクラスを通して、あなたが堂々と専門性を発信し、理想のクライアントとつながり続ける力を手に入れてください。   今すぐ「迷い」を手放し、成長の一歩を踏み出す時です！

YOUTUBE video link of this live broadcast is HERE: https://www.youtube.com/watch?v=CG6WGVWKHS4 Here are lost scenes never heard in English performed LIVE for the first time. A Japanese-American named Akiko translated these scenes for me in 2018. In this first installment, key scenes from episode #15 (of 52) will be performed live including the resolution of a major cliffhanger as well as the cliffhanger for the following episode #16. I'll do the best that I can! Plus: a movie review of "Nosferatu" & a hot tip for fans of classic "Star Trek" concerning LOST FOOTAGE RESURFACING! #thespacegiants #ambassadormagma #live #translation #live #liveperformance #acting #youtubelive #japanesemonsters #japanesetv #japanese #english #history #popculture #fun #nostalgia #goldar #1966 #1966年生 #magma #silvar #mol #gam #gammo #rodak #goa #lugomen #lostepisode #thenostalgicpodblast The Nostalgic Podblast

Fluent Fiction - Japanese: New Year, New Bonds: Haruto's Heartwarming Tokyo Tale Find the full episode transcript, vocabulary words, and more:fluentfiction.com/ja/episode/2024-12-27-23-34-02-ja Story Transcript:Ja: 東京タワーは、新年のカウントダウンイベントで活気づいていました。En: Tokyo Tower was bustling with activity during the countdown event for the New Year.Ja: 冬の冷たい空気がほっぺたを刺し、ライトアップされた東京タワーは冬の夜空を照らしていました。En: The cold winter air bit at their cheeks, and the illuminated Tokyo Tower lit up the winter night sky.Ja: 人々は、新年を迎える瞬間を心待ちにしながら塔の周囲に集まっていました。En: People gathered around the tower, eagerly awaiting the moment to welcome the New Year.Ja: ハルトは、いとこのタロウと一緒に東京に来ました。En: Haruto came to Tokyo with his cousin Taro.Ja: 大学を卒業したばかりのハルトは、自分の未来について迷っています。En: Having just graduated from college, Haruto was unsure about his future.Ja: しかし、心の中では、東京で幼なじみのアキコと再会したいと思っていました。アキコは、東京で元気に働いています。En: However, deep down, he wanted to reunite with his childhood friend Akiko, who was happily working in Tokyo.Ja: ハルトの心は複雑でした。En: Haruto's heart was conflicted.Ja: アキコは賑やかな東京で輝いて見え、自分とは違う世界にいるように感じました。En: Akiko seemed to shine in the lively city of Tokyo, and he felt as if she were in a different world from his own.Ja: 「彼女にどうやって気持ちを伝えればいいのか？」ハルトは自信がありませんでした。En: "How should I express my feelings to her?" Haruto was uncertain.Ja: しかし、タロウはいつもハルトにリスクを取ることを勧めていました。En: However, Taro always encouraged Haruto to take risks.Ja: いよいよ年越しの夜です。En: Finally, it was New Year's Eve.Ja: タロウはどこかに行ってしまい、アキコと二人きりになりました。En: Taro went off somewhere, leaving Akiko and Haruto alone together.Ja: 塔の下で、彼女の笑顔は輝いていました。En: Beneath the tower, her smile was radiant.Ja: ハルトの心臓はドキドキしていましたが、彼は心を決めました。En: Haruto's heart was racing, but he made up his mind.Ja: 「アキコ、ちょっと聞いてほしい。」ハルトは勇気を振り絞りました。En: "Akiko, can I talk to you for a moment?" Haruto mustered the courage.Ja: 「俺、自分の未来がわからなくて不安だけど、君ともう一度友達になりたい。君と一緒だと、もっと頑張れる気がする。」En: "I'm anxious because I'm not sure about my future, but I want to be friends with you again. Being with you makes me feel like I can try harder."Ja: そのとき、カウントダウンが始まりました。En: At that moment, the countdown began.Ja: 「3、2、1、新年おめでとう！」人々の歓声と共に、ハルトの心も一つの決心を迎えました。En: "3, 2, 1, Happy New Year!" As the crowd cheered, Haruto reached a decision.Ja: アキコは目を輝かせ、ハルトを見つめました。En: Akiko looked at Haruto with shining eyes.Ja: 「ハルト、一緒に進んでいこうよ。新しい年の始まりだし、何でも挑戦できるよ。」En: "Haruto, let's move forward together. It's the beginning of a new year, and we can take on anything."Ja: ハルトの心は温かくなり笑顔を見せました。En: Haruto's heart warmed, and he smiled.Ja: 新しい年の東京タワーの光が、二人の未来を照らしていました。En: The new year's lights of Tokyo Tower illuminated their future.Ja: ハルトは自信が生まれ、アキコとの絆を再び感じ始めていました。En: Haruto felt a newfound confidence and began to sense the bond with Akiko once again.Ja: 新しい一年が、二人にとってどれほど素敵なものになるか、期待でいっぱいでした。En: They were filled with anticipation about how wonderful the new year would be for both of them. Vocabulary Words:bustling: 活気づくcountdown: カウントダウンilluminated: ライトアップされたawaiting: 心待ちにするreunite: 再会するconflicted: 複雑express: 伝えるcourage: 勇気anxious: 不安mustered: 振り絞るbeginning: 始まりshine: 輝くeagerly: 熱心にmoment: 瞬間lively: 賑やかrisks: リスクradiant: 輝くcheered: 歓声を上げるshining: 目を輝かせるwarm: 温かいfuture: 未来bond: 絆anticipation: 期待wonderful: 素敵なgraduated: 卒業するchildhood: 幼なじみconfident: 自信crowd: 人々decision: 決心encouraged: 勧める

During TIFF24, I met with stage and screen actress and writer Akiko Iwase to chat about the challenges of adapting her stage play A MATTER OF SHARING for the 2023 feature film directed by Shinji Kuma. We spoke of her path to becoming an actress, writer, and working in Japan and North American film industries.#CarolynTalks #TIFF24 #JapaneseFilm #JapaneseActress#AMatterOfSharing was produced by Bion Entertainment Inc., and distributed by Flower Communications Inc.Find me on Twitter and Instagram @CarrieCNH12Buy me a coffee or pizza at https://buymeacoffee.com/carolynhinds?status=1paypal.com/paypalme/carolynhinds0525Visit Authory.com/CarolynHinds to find links to all of my published film festival coverage, writing, YouTube and other podcasts So Here's What Happened!, and Beyond The Romance.My Social Media hashtags are: #CarolynTalks #DramasWithCarrie #SaturdayNightSciFi #SHWH #KCrush Hosted on Acast. See acast.com/privacy for more information.

Du bist noch auf der Suche nach einem passenden Geschenk für deine Lieben oder möchtest dir selbst eine Auszeit gönnen über die Feiertage? Mit ihren 10 Buchempfehlungen setzen Karla und Günter dieser unruhigen Zeit etwas Entspannung entgegen. Folgende 10 Bücher machen Mut und gute Laune: Ronja von Wurmb-Seibel „Zusammen“ (Kösel): Jeder dritte Deutsche fühlt sich heute einsam. Wie wir wieder mehr in Verbindung treten und Mut fürs Miteinander finden, verrät dieser Ratgeber mit vielen Lösungen und Übungen. Britta Teckentrup „Mutig” (Prestel): Das außergewöhnlich schön illustrierte Kinderbuch erzählt davon, dass Angst und Mut zusammengehören. Ein Mädchen fürchtet sich vor einem Bären. Doch als es sich ihm nähert, wird der Bär sein Begleiter und schließlich sein Freund. Melanie Raabe „Der längste Schlaf“ (btb): Wissenschaftlerin Mara forscht über den Schlaf und hat selbst quälende Träume. Überraschend erbt sie ein Herrenhaus, das auf seltsame Weise mit ihren Träumen in Verbindung steht. Hoher Mystik-Grusel-Faktor! Curtis Sittenfeld „Romantic Comedy“ (Dumont): Comedy-Autorin Sally macht sich in ihren Sketches über Machtdynamiken in Beziehungen lustig. Bis Popstar Noah in ihr Leben tritt. Eine funkelnde Mediensatire und köstliche Romantic Comedy, die einfach gute Laune bringt. Juan Gómez-Jurado und Bárbara Montes „Amanda Black“ (cbj): Die 12-jährige Amanda erfährt, dass sie das letzte Mitglied eines Geheimbundes und einer Schatzjäger-Familie ist. Ihre Mission: Die Menschheit vor gefährlicher Magie beschützen. Klischeefrei, cool und spannend für Kinder ab 9 Jahren. Jan-Philipp Sendker „Akikos stilles Glück“ (Blessing): Die 29-jährige Akiko lebt als Single in Tokio. Eines Abends trifft sie ihre erste Liebe wieder. Kento lebt zurückgezogen als Hikikomori, trotzdem hilft er ihr, mit der Tragik ihres Lebens umzugehen. Andrea Wulf „Fabelhafte Rebellen“ (C.Bertelsmann): Nach der französischen Revolution ist der Absolutismus wieder zurück. Ein turbulenter Freundeskreis rund um Goethe, Schiller, Schelling und Hegel wagt es dennoch, radikale Ideen zu verfechten. Inspirierende und unterhaltsame deutsche Geistesgeschichte. Rosalind Brown „Übung“ (Blessing): Oxford-Studentin Annabell arbeitet einen Tag lang an einem Essay über Shakespeares Sonette, schweift jedoch immer wieder ab. Das Buch gewährt à la Virginia Woolf einen präzisen Einblick in ihr Innenleben. Alexandra Schlüter „Winterreise“ (Prestel): Eine wunderschön bebilderte Reise durch das winterliche Deutschland. Mit vielen Rezepten, Literaturtipps, Anekdoten und einem liebevollen Blick auf Menschen und Traditionen. Sara Klatt „Das Land, das ich dir zeigen will“ (Penguin): Eine junge Frau trampt durch Israel und begegnet auf ihrer Reise Menschen, die so vielschichtig sind wie das Land selbst. Ein verblüffender Roman über das moderne und das vergangene Israel, der für Frieden und Verständigung wirbt. +++ Viel Spaß mit dieser Folge. Wir freuen uns auf euer Feedback an podcast@penguinrandomhouse.de! +++ Unsere allgemeinen Datenschutzrichtlinien finden Sie unter https://art19.com/privacy. Die Datenschutzrichtlinien für Kalifornien sind unter https://art19.com/privacy#do-not-sell-my-info abrufbar.

Okamoto, Akiko www.deutschlandfunkkultur.de, Fazit

Above is a brief video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to audio and external citationsEric Topol (00:06):Well, hello it's Eric Topol with Ground Truths, and I'm really delighted to welcome Dr. Rachael Bedard, who is a physician geriatrician in New York City, and is actually much more multidimensional, if you will. She's a writer. We're going to go over some of her recent writings. She's actually quite prolific. She writes in the New Yorker, New York Magazine, New York Times, New York Review of Books. If it has New York in front of it, she's probably writing there. She's a teacher. She works on human rights, civil rights, criminal justice in the prison system. She's just done so much that makes her truly unique. That's why I really wanted a chance to meet her and talk with her today. So welcome, Rachael.Rachael Bedard (00:52):Thank you, Dr. Topol. It's an honor to be here.Eric Topol (00:55):Well, please call me Eric and it's such a joy to have a chance to get acquainted with you as a person who is into so many different things and doing all of them so well. So maybe we'd start off with, because you're the first geriatrician we've had on this podcast.Practicing Geriatrics and Internal MedicineEric Topol (01:16):And it's especially apropos now. I wanted maybe to talk about your practice, how you got into geriatrics, and then we'll talk about the piece you had earlier this summer on aging.Rachael Bedard (01:32):Sure. I went into medicine to do social justice work and I was always on a funny interdisciplinary track. I got into the Mount Sinai School of Medicine through what was then called the Humanities and Medicine program, which was an early acceptance program for people who were humanities focused undergrads, but wanted to go into medicine. So I always was doing a mix of politics and activist focused work, humanities and writing, that was always interested in being a doctor. And then I did my residency at the Cambridge Health Alliance, which is a social medicine program in Cambridge, Massachusetts, and my chief residency there.(02:23):I loved being an internist, but I especially loved taking care of complex illness and I especially loved taking care of complex illness in situations where the decision making, there was no sort of algorithmic decision-making, where you were doing incredibly sort of complex patient-centered shared decision making around how to come up with treatment plans, what the goals of care were. I liked taking care of patients where the whole family system was sort of part of the care team and part of the patient constellation. I loved running family meetings. I was incredibly lucky when I was senior resident and chief resident. I was very close with Andy Billings, who was one of the founders of palliative care and in the field, but also very much started a program at MGH and he had come to work at Cambridge Hospital in his sort of semi-retirement and we got close and he was a very influential figure for me. So all of those things conspired to make me want to go back to New York to go to the Sinai has an integrated geriatrics and palliative care fellowship where you do both fellowships simultaneously. So I came to do that and just really loved that work and loved that medicine so much. There was a second part to your question.Eric Topol (03:52):Is that where you practice geriatrics now?Rachael Bedard (03:55):No, now I have ever since finishing fellowship had very unusual practice settings for a geriatrician. So right out of fellowship, I went to work on Rikers Island and then New York City jail system, and I was the first jail based geriatrician in the country, which is a sort of uncomfortable distinction because people don't really like to think about there being a substantial geriatric population in jails. But there is, and I was incredibly lucky when I was finishing fellowship, there was a lot of energy around jail healthcare in New York City and I wrote the guy who was then the CMO and said, do you think you have an aging problem? And he said, I'm not sure, but if you want to come find out, we'll make you a job to come find out. And so, that was an incredible opportunity for someone right out of fellowship.(04:55):It meant stepping off the sort of academic track. But I went and worked in jail for six years and took care of older folks and people with serious illness in jail and then left Rikers in 2022. And now I work in a safety net clinic in Brooklyn that takes care of homeless people or people who have serious sort of housing instability. And that is attached to Woodhull Hospital, which is one of the public hospitals in New York City. And there I do a mix of regular internal medicine primary care, but I preferentially see the older folks who come through, which is a really interesting, painful, complicated patient population because I see a fair amount of cognitive impairment in folks who are living in the shelter system. And that's a really hard problem to address.Frailty, The Aged, and LongevityEric Topol (05:54):Well, there's a theme across your medical efforts. It seems to me that you look after the neglected folks, the prisoners, the old folks, the homeless people. I mean that's kind of you. It's pretty impressive. And there's not enough of people like you in the medical field. Now, no less do you do that, but of course you are a very impressive author, writer, and of many topics I want to get into with you, these are some recent essays you've written. The one that piqued my interest to start to understand who you were and kind of discover this body of work was the one that you wrote related to aging and President Biden. And that was in New York Times. And I do want to put in a quote because as you know very well, there's so much interest in longevity now.Eric Topol (06:51):Interrupting the aging process, and this one really stuck with me from that op-ed, “Time marches forward, bodies decline, and the growing expectation that we might all live in perfect health until our 100th birthdays reflects a culture that overprizes longevity to the point of delusion.” So maybe if you could tell us, that was a rich piece, you got into frailty, you related it to the issues that were surrounding President Biden who at that time had not withdrawn from the race. But what were you thinking and what are your thoughts about the ability to change the aging process?Rachael Bedard (07:36):I am very interested in, I mean, I'm incredibly interested in the science of it. And so, I guess I think that there are a few things.(07:49):One thing is that the framework that, the part that gives me pause the most is this framework that anything less than perfect health is not a life worth living. So if you're going to have a long life, life should not just be long and sort of healthy in relative terms to your age cohort, but healthy that when you're 80 you should feel like you have the health of a 45-year-old is my understanding of the culture of longevity science. And while I understand why that's aspirational and everybody worry about my body's decline, I think it's a really problematic thing to say that sick bodies are bodies that have disability or people who have cognitive difference are somehow leading lesser lives or lives that are not meaningful or not worth living. I think it's a very, very slippery slope. It puts you in a place where it sort of comes up against another trend or another emerging cultural trend, which is really thinking a lot about physician-assisted suicide and end of life choices.(09:04):And that in some ways that conversation can also be very focused on this idea that there's just no way that it's worth living if you're sick. And that's just not true, I think, and that's not been true for many, many, many of my patients, some of whom have lived with enormous disability and incredible burden of illness, people who are chronically seriously ill and are still leading lives that for them and for the people who love them are filled with meaning. So that's my concern about the longevity stuff. I'm interested in the science around the longevity stuff for sure. I'm interested in, I think we're living in this really interesting moment where there's so much happening across so many of the chronic disease fields where the things that I think have been leading to body decay over the last several decades for the majority of the population, we're sort of seeing a lot of breakthroughs in multiple fronts all at once. And that's really exciting. I mean, that's really exciting. And so, certainly if it's possible to make it to 100 in wonderful health, that's what I'd wish for all of us. But to hold it up as the standard that we have to achieve, I think is both unrealistic and a little myopic.Eric Topol (10:28):Yeah. Well, I certainly agreed with that and I think that that particular essay resonated so well and you really got into frailty and the idea about how it can be potentially prevented or markedly delayed. And I think before we move on to one of those breakthroughs that you were alluding to, any comments about the inevitability of frailty in people who are older, who at some point start to get the dwindles, if you will, what do you have to say about that?Rachael Bedard (11:11):Well, from a clinical standpoint, I guess the caveat versus that not everybody becomes frail and dwindles exactly. Some people are in really strong health up until sort of their final years of life or year of life and then something happens, they dwindle quickly and that's how they die. Or some people die of acute events, but the vast majority of us are going to become more frail in our final decades than we are in our middle decades. And that is the normal sort of pattern of wear and tear on the body. And it is an extraordinary framework, I think frailty because the idea of this sort of syndrome of things where it's really not a disease framework, it is a syndrome framework and it's a framework that says many, many small injuries or stressors add up to create a lot of stress and change in a body and trauma for our body. And once you are sort of past a tipping point of an amount of stress, it's very hard to undo those things because you are not sort of addressing one pathologic process. You're addressing, you're trying to mitigate many processes all at once.(12:31):When I wrote that piece, it was inspired by the conversation surrounding President Biden's health. And I was particularly struck by, there was a huge amount of clinical speculation about what was going on with him, right? I'm sure you remember there were people, there was all of this talk about whether he had Parkinson's and what his cognitive status was. And it felt to me like there was an opportunity to do some public education around the idea that you need not have one single sort of smoking gun illness to explain decline. What happens to most of us is that we're going to decline in many small ways sort of simultaneously, and it's going to impact function when it tips over a little bit. And that pattern of decline is not going to be steady day over day worsening. It's going to be up and down. And if you slept better the night before, you might have a better day the next day. And if you slept badly, you might have a worse day. And without knowing anything specific about his clinical situation, it felt like a framework that could explain so much of what we were seeing in public. And it was important also, I think to say that nothing was necessarily being hidden from anybody and that this is the kind of thing that, this has accumulated stress over time that then presents suddenly all at once after having been submerged.Eric Topol (14:01):Yeah, you reviewed that so well about the wear and tear and everything related to that. And before I move on to the second topic, I want to just circle back to something you alluded to, which is when Peter Attia wrote about this medicine 3.0 and how you would be compressed and you'd have no comorbidities, you'd have no other illnesses and just fall off the cliff. As a geriatrician, do you think that that is even conceivable?Rachael Bedard (14:35):No. Do you think it is?Eric Topol (14:37):No, but I just wanted to check the reality. I did challenge on an earlier podcast and he came up with his pat answer. But no, there's no evidence of that, that maybe you can delay if there ever was a way to do that. But I think there's this kind of natural phenomena that you just described, and I'll refer people also to that excellent piece that you get into it more.Rachael Bedard (15:06):Peter Attia, I mean, he is certainly the sort of standard bearer in my mind of that movement and that science or that framework of thinking about science. And there's stuff in there that's really valuable. The idea of thinking about lifestyle in your middle decades is having meaningful impact on how you will age, what your final years will look like. That seems intuitively true, I think. And so, thinking about his emphasis on exercise, I mean, his emphasis on exercise is particularly intense and not super achievable for the average person, but the idea that you should sort of be thinking about keeping your body strong because it will decline eventually. And so, you want to do that from a higher peak. That makes a lot of sense to me. The idea that where we sort of draw pathologic disease cutoffs is obviously a little bit arbitrary. And so, wanting to think about optimizing pre-disease states and doing prevention, that's obviously, I think pretty appealing and interesting. It's just really in an evidence free zone.Ozempic for the IndigentEric Topol (16:18):Yeah, that's what I confronted him with, of course, he had a different perspective, but you summed that up really well. Now let's switch to a piece you had in New York magazine. It was entitled, What If Ozempic Is Just a Good Thing? And the reason, of course, this ties into the first thing we're discussing. There's even talk now, the whole GLP-1 family of drugs with the dual triple receptors, pills to come that we're going to be able to interrupt a path towards Alzheimer's and Parkinson's. Obviously you've already seen impact in heart disease, liver disease, kidney disease way before that, diabetes and obesity. So what are your thoughts? Because you wrote a very interesting, you provided a very interesting perspective when you wrote that one.Rachael Bedard (17:11):So that piece I wrote because I have this unbelievably privileged, interesting clinical practice. In New York City, there is public health insurance basically available to anybody here, including folks who are undocumented. And the public hospital system has pharmacies that are outpatient pharmacies that have, and New York Medicaid is very generous and they arranged through some kind of brilliant negotiating. I don't quite know how to make Ozempic to make semaglutide available to people who met criteria which meant diabetes plus obesity, but that we could prescribe it even for our very, very poor patients and that they would be able to get it reliably, that we would have it in stock. And I don't know how many other practices in the country are able to reliably provide GLP-1s to marginalized folks like that. I think it feels like a really rare opportunity and a very distinct perspective.(18:23):And it has just been the most amazing thing, I think to have this class of drugs come along that, as you say, addresses so many problems all at once with at least in my prescribing experience, a relatively mild tolerable side effect profile. I have not had patients who have become incredibly sick with it. And for folks where making that kind of impact on their chronic illness is so critical to not just their longevity, but their disease status interacts so much with their social burden. And so, it's a very meaningful intervention I think around poverty actually.(19:17):I really feel that almost all of the popular press about it has focused very much on use amongst the wealthy and who's getting it off label and how are they getting it and which celebrities are taking it, and what are the implications for eating and diet culture and for people who have eating disorders. And that's a set of questions that's obviously sort of interesting, but it's really interesting in a very rarefied space. There's an unbelievable diabetes epidemic in this country, and the majority of people who have diabetes are not the people who are getting written about over and over again in those pieces. It's the patients that I take care of, and those people are at risk of ending up on dialysis or getting amputations. And so, having a tool this effective is really miraculous feeling to me.Eric Topol (20:10):Well, it really gives me some hope because I don't know any program like that one, which is the people who need it the most. It's getting provided for them. And we have been talking about a drug that costs a thousand dollars a month. It may get down to $500 a month, but that's still a huge cost. And of course, there's not much governmental coverage at this point. There might be some more for Medicare, Medicaid, whatever in the future, but it's really the original criteria of diabetes, and it took almost 20 years to get to where we are right now. So what's so refreshing here is to know that there's at least one program that is helping to bridge the inequities and to not make it as was projected, which was, as you say, for celebrities and wealthy people more exclusively, so that's great. And we still don't know about the diverse breadth of these effects, but as you well know, there's trials in Alzheimer's. I spoke to Steve Horvath recently on the podcast and he talked about how it's reset the epigenetic clock, GLP-1.Rachael Bedard (21:24):Does he think so?Eric Topol (21:26):Whoa. Yeah, there was evidence that was just presented about that. I said, well, if that does correspond to aging, the thing that we spoke about first, that would be very exciting.Rachael Bedard (21:37):It's so wild. I mean, it's so exciting. It's so exciting to me on so many levels. And one of them is it's just exploding my mental model of disease pathogenesis, and it's making me think, oh my goodness, I have zero idea actually how metabolism and the brain and sort of cardiovascular disease, all of those things are obviously, what is happening in the interplay between all of those different systems. It's really so much more complicated and so much more interdependent than I understood it to be. I am really optimistic about the Alzheimer's trial. I am excited for those results, and I think we're going to keep seeing that it prevents different types of tumors.Eric Topol (22:33):Yeah, no, and that's been shown at least certainly in obese people, that there's cancers that gets way reduced, but we never had a potent anti-inflammatory that works at the brain and systemically like this before anyone loses the weight, you already see evidence.Long Covid and ME/CFS(22:50):It is pretty striking. Now, this goes back to the theme that was introduced earlier about looking after people who are neglected, who aren't respected or generally cared for. And I wanted to now get into Long Covid and the piece you wrote in the New Yorker about listening to patients, called “what would it mean for scientists to listen to patients?” And maybe you can talk about myalgic encephalitis/chronic fatigue (ME/CFS), and of course Long Covid because that's the one that is so pervasive right now as to the fact that these people don't get respect from physicians. They don't want to listen to their ailments. There's no blood tests, so there's no way to objectively make a diagnosis supposedly. And they're basically often dismissed, or their suffering is discounted. Maybe you can tell us again what you wrote about earlier this year and any updated thoughts.Rachael Bedard (24:01):Have you had my friend Harlan Krumholz on the show to talk about the LISTEN study?Eric Topol (24:04):Not yet. I know Harlan very well. Yes.Eric Topol (24:11):I know Akiko Iwasaki very well too. They're very, very close.Rachael Bedard (24:14):So, Akiko Iwasaki and Harlan Krumholz at Yale have been running this research effort called the LISTEN study. And I first learned about it sometime in maybe late 2021. And I had been really interested in the emerging discourse around chronic illness in Long Covid in the 2021. So when we were past the most acute phase of the pandemic, and we were seeing this long tail of sequelae in patients, and the conversation had really shifted to one that was about sort of trying to define this new syndrome, trying to understand it, trying to figure out how you could diagnose it, what were we seeing sort of emerge, how are we going to draw boxes around it? And I was so interested in the way that this syndrome was really patient created. It came out of patients identifying their own symptoms and then banning together much, much faster than any kind of institutional science can ever work, getting into message boards together or whatever, and doing their own survey work and then coming up with their own descriptive techniques about what they were experiencing.(25:44):And then beyond that, looking into the literature and thinking about the treatments that they wanted to try for themselves. Patients were sort of at the forefront of every step of recognizing, defining, describing this illness presentation and then thinking about what they wanted to be able to do for themselves to address it. And that was really interesting to me. That was incredibly interesting to me. And it was also really interesting because by, I don't know exactly when 2021 or 2022, it was already a really tense landscape where it felt like there were real factions of folks who were in conflict about what was real and what wasn't real, how things ought to be studied, who ought to be studying them, what would count as evidence in this realm. And all of those questions were just really interesting to me. And the LISTEN study was approaching them in this really thoughtful way, which was Harlan and Akiko sort of partnering really closely with patients who enrolled.(26:57):And it's a decentralized study and people could enroll from all over the world. There's a portion of patients who do have their blood work evaluated, but you can also just complete surveys and have that data count towards, and those folks would be from anywhere in the world. Harlan did this amazing, amazing work to figure out how to collect blood samples from all over the country that would be drawn at home for people. So they were doing this decentralized study where people from their homes, from within the sort of circumstances of their lives around their chronic illness could participate, which that was really amazing to me. And then they were partnering really thoughtfully with these patients just to figure out what questions they wanted to ask, how they wanted to ask them, and to try to capture a lot of multimodal data all at once.(27:47):Survey data, journaling so people could write about their own experience in a freeform journal. They were collecting blood samples, and they were holding these town halls. And the town halls were on a regular basis, Harlan and Akiko, and anybody who was in the study could come on, could log onto a Zoom or whatever, and Harlan and Akiko and their research staff would talk about how things were going, what they were working on, what questions they had, what the roadblocks were, and then they would answer questions from their participants as the study was ongoing. And I didn't think that I had ever heard of something quite like that before. Have you ever heard of anything?Eric Topol (28:32):No. I mean, I think this is important to underscore, this was the first condition that was ever patient led, patient named, and basically the whole path was laid by the patient. So yes, and everything you summarize is so well as to the progress that's been made. Certainly, Harlan and Akiko are some of the people that have really helped lead the way to do this properly as opposed to, unfortunately one and a half billion dollars that have been put to the NIH for the RECOVER efforts that haven't yet led to even a significant clinical trial, no less a validated treatment. But I did think it was great that you spotlighted that just because again, it's thematic. And that gets me to the fourth dimension, which is you're the first prison doctor I've ever spoken to. And you also wrote a piece about that called, “the disillusionment of a Rikers Island Doctor” in the New Yorker, I think it was. And I wonder if you could tell us, firstly, now we're four years into Covid, you were for a good part of that at Rikers Island, I guess.The Rikers Island Prison Doctor During CovidRachael Bedard (30:00):I was, yeah.Eric Topol (30:00):Yeah. And what could be a more worrisome spot to be looking after people with Covid in a prison? So maybe you could just give us some insight about all that.Rachael Bedard (30:17):Yeah, it was really, I mean, it was the wildest time, certainly in my career probably that I'll ever have. In the end of February and beginning of March of 2020, it became very apparent to my colleagues and I that it was inevitable that this virus that was in Wuhan and in Italy was coming to the US. And jails are, we sort of jokingly described them as the worst cruise ships in the world. They are closed systems where everybody is eating, sleeping, going to the bathroom, everything on top of each other. There's an incredible amount of excess human contact in jails and prisons because people don't have freedom of movement and they don't get to do things for themselves. So every single, somebody brings you your mail, somebody brings you your meals, somebody brings you your medications. If you're going to move from point A to point B, an officer has to walk you there. So for a virus that was going to spread through what we initially thought was droplets and then found out was not just droplets but airborne, it was an unbelievably high-risk setting. It's also a setting where folks tend to be sicker than average for their age, that people bring in a lot of comorbidity to the setting.(31:55):And it's not a setting that does well under stress. I mean, jails and prisons are places that are sort of constitutionally violent, and they're not systems that adapt easily to emergency conditions. And the way that they do adapt tends to be through repressive measures, which tends to be violence producing rather than violence quelling. And so, it was just an incredibly scary situation. And in mid-March, Rikers Island, the island itself had the highest Covid prevalence of anywhere in the country because New York City was the epicenter, and Rikers was really the epicenter within New York. It was a wild, wild time. Our first seriously ill patient who ended up getting hospitalized. That was at that time when people were, we really didn't understand very much about what Covid looked like. And there was this guy sitting on the floor and he said, I don't know. I can't really get up.(32:59):I don't feel well. And he had an O2 stat of 75 or something. He was just incredibly hypoxic. It's a very scary setting for that kind of thing, right? It's not a hospital, it's not a place where you can't deliver ICU level care in a place like that. So we were also really worried about the fact that we were going to be transferring all of these patients to the city hospitals, which creates a huge amount of extra burden on them because an incarcerated patient is not just the incarcerated patients, the officers who are with that person, and there are special rules around them. They have to be in special rooms and all of these things. So it was just a huge systems crisis and really painful. And we, early on, our system made a bunch of good guesses, and one of our good guesses was that we should just, or one of our good calls that I entirely credit my bosses with is that they understood that we should advocate really hard to get as many people out as we could get out. Because trying to just manage the population internally by moving people around was not going to be effective enough, that we really need to decant the setting.(34:18):And I had done all of this work, this compassionate release work, which is work to get people who are sick out of jail so that they can get treatment and potentially die in a free setting. And so, I was sort of involved in trying to architect getting folks who were sort of low enough security risks out of jail for this period of time because we thought that they would be safer, and 1500 people left Rikers in the matter of about six weeks.Rachael Bedard (34:50):Which was a wild, wild thing. And it was just a very crazy time.Eric Topol (34:56):Yeah. Well, the word compassion and you go together exceptionally well. I think if we learn about you through your writings, that really shines through and what you've devoted your care for people in these different domains. This is just a sampling of your writings, but I think it gives a good cross section. What makes you write about a particular thing? I mean, obviously the Rikers Island, you had personal experience, but why would you pick Ozempic or why would you pick other things? What stimulates you to go after a topic?Rachael Bedard (35:42):Sometimes a lot of what I write about relates to my personal practice experience in some way, either to geriatrics or death and dying or to the criminal justice system. I've written about people in death row. I've written about geriatrics and palliative care in sort of a bunch of different ways. I am interested in topics in medicine where things are not yet settled, and it feels very of the moment. I'm interested in what the discourse is around medicine and healthcare. And I am interested in places where I think the discourse, not just that I'm taking a side in that discourse, but where I think the framework of the discourse is a little bit wrong. And I certainly feel that way about the Ozempic discourse. And I felt that way about the discourse around President Biden, that we're having not just a conversation that I have a strong opinion about, but a conversation that I think is a little bit askew from the way that we ought to be thinking about it.Eric Topol (36:53):And what I love about each of these is that you bring all that in. You have many different points of view and objective support and they're balanced. They're not just trying to be persuasive about one thing. So, as far as I know, you're extraordinarily unique. I mean, we are all unique, but you are huge standard deviations, Rachael. You cover bases that are, as I mentioned, that are new to me in terms of certainly this podcast just going on for now a couple of years, that is covering a field of both geriatrics and having been on the corrections board and in prison, particularly at the most scary time ever to be working in prison as a physician. And I guess the other thing about you is this drive, this humanitarian theme. I take it you came from Canada.Rachael Bedard (37:59):I did.Eric Topol (37:59):You migrated to a country that has no universal health.Rachael Bedard (38:03):That's right.Eric Topol (38:03):Do you ever think about the fact that this is a pretty pathetic situation here?Rachael Bedard (38:08):I do. I do think about it all the time.Eric Topol (38:10):In our lifetime, we'll probably never see universal healthcare. And then if you just go a few miles up north, you pretty much have that.Rachael Bedard (38:18):Yeah, if you've lived in a place that has universal healthcare and you come here, it's really sort of hard to ever get your mind around. And it has been an absolute possessing obsession of my entire experience in the US. I've now been here for over 20 years and still think it is an unbelievably, especially I think if you work with marginalized patients and how much their lack of access compounds the difficulty of their lives and their inability to sort of stabilize and feel well and take care of themselves, it's really frustrating.Advice for Bringing Humanities to Medicine in a CareerEric Topol (39:14):Yeah, yeah. Well, I guess my last question to you, is you have weaved together a career that brings humanities to medicine, that doesn't happen that often. What's your advice to some of the younger folks in healthcare as to how to pull that off? Because you were able to do it and it's not easy.Rachael Bedard (39:39):My main advice when people ask me about this, especially to students and to residents who are often the people who are asking is to write when you can or pursue your humanities interests, your critical interests, whatever it is that you're doing. Do it when you can, but trust that your career is long and that you have a lot of time. Because the thing that I would say is I didn't start publishing until I was in fellowship and before that I was busy because I was learning to become a doctor. And I think it's really important that my concern about being a doctor who's a hybrid, which so many of us are now. A doctor or something else is you really do want to be a good doctor. And becoming a good doctor is really hard. And it's okay if the thing that is preoccupying you for the first 10 years of your training is becoming a great clinician. I think that's a really, really important thing to do. And so, for my first 10 years for med school and residency and chief residency and fellowship, I would write privately on the side a fair amount, but not try to publish it, not polish that work, not be thinking in sort of a careerist way about how I was going to become a doctor writer because I was becoming a doctor. And that was really preoccupying.(41:08):And then later on, I both sort of had more time and mental space to work on writing. But also, I had the maturity, I think, of being a person who was comfortable in my clinical identity to have real ideas and insights about medicine that felt different and unique to me as opposed to, I barely understand what's going on around me and I'm trying to pull it together. And that's how I would've been if I had done it more, I think when I was younger. Some people are real prodigies and can do it right out the gate, but I wasn't like that.Eric Topol (41:42):No, no, I think that's really sound advice because that's kind of the whole foundation for everything else. Is there a book in the works or will there be one someday?Rachael Bedard (41:53):There may be one someday. There is not one now. I think about it all the time. And that same advice applies, which is I believe in being a late bloomer and taking your time and figuring out what it is you really want to do.Eric Topol (42:10):Yeah. Well, that's great. Have I missed anything? And obviously we only can get to know you in what, 40 minutes to some extent, but have I not touched on something that you want to bring up?Rachael Bedard (42:23):No, I don't think so. Thank you for this conversation. It's been lovely.Eric Topol (42:28):No, I really enjoyed it. I'll be following your career. It's extraordinary already and you've got decades ahead to make an impact and obviously thinking of all these patients that you look after and have in the past, it's just extraordinary. So what a joy to talk with you, Rachael, and I hope we'll have a chance to do that again in the times ahead.Rachael Bedard (42:51):Me as well. Thank you so much for inviting me.**********************************************Thank you for listening, reading or watching!The Ground Truths newsletters and podcasts are all free, open-access, without ads.Please share this post/podcast with your friends and network if you found it informative!Voluntary paid subscriptions all go to support Scripps Research. Many thanks for that—they greatly help fund our education and summer internship programs.Thanks to my producer Jessica Nguyen and Sinjun Balabanoff for audio and video support at Scripps Research.Note: you can select preferences to receive emails about newsletters, podcasts, or all I don't want to bother you with an email for content that you're not interested in. Get full access to Ground Truths at erictopol.substack.com/subscribe

Episode 2: Sign - Between Fact and Distortion A look into Chae-ok's past after she receives the Najin. Ho-jae invites Chae-ok to partner up. Ho-jae asks Yong-gil who Jang Tae-sang was. Seung-jo fights Chae-ok and gets in trouble. Ho-jae tries to learn more about Silverbill after she disappears from the hospital. The Chairman of Jeongseung reminds "Scary Dude" that he is replaceable. Chae-ok agrees to work with Ho-jae. Seung-jo pulls out a picture of a familiar person, Myeong-jo aka Akiko. Find us on YouTube and Apple Podcasts Follow us on Instagram @thekdramashow https://www.instagram.com/thekdramashow/  Email : the kdramashowashandkim@gmail.com Thanks for listening!!

Fluent Fiction - Japanese: Hiroshi's Whirlwind Halloween: A Tradition in the Making Find the full episode transcript, vocabulary words, and more:fluentfiction.org/hiroshis-whirlwind-halloween-a-tradition-in-the-making Story Transcript:Ja: 秋の日差しが柔らかく窓から差し込む中、精神病棟は静かだった。En: In the gentle autumn sunlight streaming through the windows, the psychiatric ward was quiet.Ja: 壁にはパステルカラーの絵が描かれ、穏やかな光が差し込んでいる。En: The walls were adorned with pastel-colored drawings, and peaceful light filled the space.Ja: その中で、ヒロシは興奮していた。En: Amidst this tranquility, Hiroshi was excited.Ja: 彼の心には一つの考えが浮かんでいた。「ハロウィンだ！」と思ったのだ。En: A thought had popped into his mind: "It's Halloween!"Ja: ヒロシは休日を愛する患者だ。En: Hiroshi is a patient who loves holidays.Ja: 彼は病棟に小さな変化を起こしたかった。En: He wanted to make a small change in the ward.Ja: そこで、かぼちゃの飾りと蜘蛛の巣を用意した。彼は、みんなを驚かせようと決心していた。En: So, he prepared pumpkin decorations and spider webs, determined to surprise everyone.Ja: アキコ看護師は、ヒロシの情熱を知っていた。En: Nurse Akiko was aware of Hiroshi's enthusiasm.Ja: 彼女もまた、彼のポジティブなエネルギーを大切にしていた。En: She also valued his positive energy.Ja: しかし、規則は規則だ。飾りを許可することはできなかった。En: However, rules were rules, and she couldn't allow decorations.Ja: 「ヒロシさん、これを片付けましょう」とアキコは優しく言った。En: "Hiroshi, let's put these away," Akiko said gently.Ja: 「でも、ハロウィンじゃない？」ヒロシは困惑した。En: "But isn't it Halloween?" Hiroshi asked, puzzled.Ja: 「それは来月です。でも、いい考えがあります」と彼女は微笑んだ。En: "That's next month, but I have an idea," she replied with a smile.Ja: ヒロシは、他の計画を考え始めた。En: Hiroshi began to think of other plans.Ja: しかし、彼の心には直ぐに別の考えが浮かんだ。「やっぱり、今がチャンスだ」と。En: Yet another thought quickly emerged in his mind: "This is the chance!"Ja: ある日、ヒロシは病棟の隅で大きな蜘蛛の飾りをこっそり準備していた。En: One day, Hiroshi was secretly preparing a large spider decoration in the corner of the ward.Ja: その光景を見たアキコは微笑んだ。En: Seeing this, Akiko smiled.Ja: 「ヒロシさん、ちょっとお話できますか？」優しい声で呼び止めた。En: "Hiroshi, can we have a chat?" she called out in a kind voice.Ja: 「ヒロシさん、来月のハロウィンに向けて準備を始めましょう。En: "Hiroshi, why don't we start preparing for next month's Halloween?Ja: もっと大きなパーティを開くのはどうですか？」アキコは提案した。En: How about organizing a bigger party?" Akiko suggested.Ja: ヒロシは考え込み、やがて笑顔になった。En: Hiroshi thought it over and then broke into a smile.Ja: 「それはすごくいいアイデアだ！もっと楽しいね！」En: "That's a great idea! It'll be even more fun!"Ja: その日から、ヒロシは秋の長い時間を使って計画を始めた。En: From that day on, Hiroshi began to use the long autumn days to start planning.Ja: アキコと一緒に材料を集め、他の患者たちとも相談した。En: Together with Akiko, they gathered materials and consulted with the other patients.Ja: 皆の目には、期待の光が輝き始めた。En: A light of anticipation began to shine in everyone's eyes.Ja: 最終的に、ハロウィンのパーティは大成功だった。En: In the end, the Halloween party was a big success.Ja: ヒロシは、自分のエネルギーを上手に使うことを学んだ。En: Hiroshi learned how to channel his energy effectively.Ja: 未来のイベントを楽しみに待ちながら、彼は微笑んでいた。En: Looking forward to future events, he smiled.Ja: いまや、ヒロシは計画の達人だった。En: Now, Hiroshi had become a master planner.Ja: アキコ看護師も、彼の成長を誇らしく思っていた。En: Nurse Akiko felt proud of his growth.Ja: そして、病棟には新たな伝統が生まれた。En: And so, a new tradition was born in the ward.Ja: 秋になると、患者たちは新しいハロウィンのアイデアを考え始めた。En: As autumn approached, patients started coming up with new Halloween ideas.Ja: ヒロシの情熱は、他の人たちの心も動かしていたのだった。En: Hiroshi's enthusiasm had touched the hearts of others as well. Vocabulary Words:gentle: 柔らかくpsychiatric ward: 精神病棟adorned: 描かれtranquility: 穏やかなenthusiasm: 情熱puzzled: 困惑emerged: 浮かんだconsulted: 相談したanticipation: 期待channel: 使うmaster planner: 計画の達人valued: 大切にしていたsmiled: 微笑んだproposed: 提案したdecorate: 飾るdetermined: 決心していたrules: 規則perhaps: やっぱりsecretly: こっそりgathered: 集めprepare: 準備success: 大成功tradition: 伝統materials: 材料approached: なるとpatient: 患者positive energy: ポジティブなエネルギーspider webs: 蜘蛛の巣pastel-colored: パステルカラーkind voice: 優しい声

SURPRISE!! We are dropping our FULL REVIEW of GyeongSeong Creature for your listening pleasure! We are so excited about the release of GSC Season 2 - exclusively on Netflix!! *Disclaimer* This show is intense with gore, violence, torture and experimentation. If this is something that would be too much, we advise that you skip this season and check out some of our other content and come back to us with our other seasons!! Introduction: A story is told through a set of stills. Focusing on a girl who falls in water. Little creatures are in the water. She is able to get out. Wherever she goes she is followed by carnage. She is caged but turns into something scary. Episode 1: Najin - Between Good and Evil March 1945, under the Japanese occupation, we meet Jang Tae-sang. He is the Master of the House of Golden Treasure. He is known as the "King of Information". If you want to find items, people or want information, Jang Tae-sang is your man. He is told that he must find a woman named Myeon-ja a.k.a Akiko, by Commissioner Ishikawa. Yoon Chae-ok and her father Jung-won are sleuths, who make a living finding those who are lost. The duo is searching for a man, Sachimoto. They go to HGT in hopes that information can be found. In cells, people are being held. Two women are selected and are now being part of an experiment. Lt. Kato is determined to use a little creature called a Najin in his experiments. An introduction is made between Tae-sang and Chae-ok and her father to see if a partnership can be made. "I can change my principals to suit my needs." A creature has been created. Keep an eye out, because Season 3 AND 4 of the KDrama Show will be releasing simultaneously!! Find us on YouTube and Apple Podcasts Follow us on Instagram @thekdramashow Email : the kdramashowashandkim@gmail.com Thanks for listening!!

Fluent Fiction - Japanese: Mystical Moments: Creativity Rekindled in Bamboo Grove Find the full episode transcript, vocabulary words, and more:fluentfiction.org/mystical-moments-creativity-rekindled-in-bamboo-grove Story Transcript:Ja: 秋の晴れた朝、嵐山竹林は静かに光を浴びていました。En: On a clear autumn morning, the Arashiyama Bamboo Grove quietly basked in the light.Ja: 長い竹のトンネルが風にそよぎ、美しい緑の世界が広がっています。En: A long tunnel of bamboo swayed in the wind, spreading out a beautiful green world.Ja: ヒロシとアキコは、この神秘的な場所で旅行ドキュメンタリーを制作していました。En: Hiroshi and Akiko were working on a travel documentary in this mysterious place.Ja: ヒロシは完璧を求める映画監督です。En: Hiroshi is a director seeking perfection.Ja: 彼のカメラは、日本の景色の本質を捉えます。En: His camera captures the essence of the Japanese landscape.Ja: でも、最近は創造性を失うことが怖いです。En: However, lately, he fears losing his creativity.Ja: アキコは情熱的な作家で、心に響く物語を書きたいと思っています。En: Akiko, a passionate writer, wants to craft stories that resonate deeply.Ja: 彼女もまた、大きな作品を求めています。En: She, too, is in search of a significant project.Ja: その日は秋分の日。特別な一日でした。En: That day was the autumnal equinox, a special day.Ja: ヒロシとアキコは、竹林の美しさを映像にしたいと思っていました。En: Hiroshi and Akiko wanted to capture the beauty of the bamboo grove on film.Ja: しかし、突然の雨が計画を狂わせました。En: However, a sudden downpour disrupted their plans.Ja: ヒロシはイライラしています。「完璧なシーンが、これでは撮れない」と思うからです。En: Hiroshi was frustrated, thinking, "I can't capture the perfect scene like this."Ja: 「気にしないで」とアキコが言います。En: "Don't worry," Akiko said.Ja: 「雨には雨の良さがあるわ。」En: "Rain has its own beauty."Ja: 彼女の言葉は、ヒロシを驚かせました。En: Her words surprised Hiroshi.Ja: アキコの即興的なアプローチが、彼の計画を変えます。En: Akiko's spontaneous approach altered his plan.Ja: 雨はやがて止みました。そして、竹林に美しい霧が漂いました。En: The rain eventually ceased, and a beautiful mist lingered in the bamboo grove.Ja: ヒロシとアキコは、その神秘的な瞬間を一緒に捉えます。En: Hiroshi and Akiko captured this mystical moment together.Ja: 彼らのコラボレーションは、予想以上の成果を生みました。En: Their collaboration yielded results beyond expectations.Ja: 夕方、二人は満足感に包まれていました。En: In the evening, they were enveloped in a sense of satisfaction.Ja: 「あなたのアイデアが良かったよ」とヒロシ。En: "Your idea was great," said Hiroshi.Ja: 「技術だけでは、得られないものがあるんだね。」En: "There are things that can't be achieved with technique alone."Ja: 「ヒロシさんのおかげで、私は更にいい物語を書けたわ」とアキコは微笑みました。En: "Thanks to you, Hiroshi, I was able to write an even better story," Akiko smiled.Ja: 二人は互いの才能に新しい敬意を持ち、一緒に仕事をしたことを喜びました。En: They both held a newfound respect for each other's talents and rejoiced in their joint efforts.Ja: こうして、ヒロシは柔軟性の大切さを学び、アキコは自信を得ました。En: In this way, Hiroshi learned the importance of flexibility, and Akiko gained confidence.Ja: 二人の作品は、竹林の魅力を見事に伝え、しばらくの間、彼らをこの穏やかな場所に結びつけていました。En: Their work beautifully conveyed the charm of the bamboo grove, tying them to this tranquil place for some time. Vocabulary Words:grove: 竹林basked: 浴びていましたswayed: そよぎessence: 本質resonate: 響くequinox: 秋分の日downpour: 突然の雨spontaneous: 即興的なceased: 止みましたmystical: 神秘的なyielded: 生みましたenveloped: 包まれていましたsatisfaction: 満足感flexibility: 柔軟性tranquil: 穏やかなbamboo: 竹documentary: ドキュメンタリーdirector: 映画監督capture: 捉えますcreativity: 創造性significant: 大きなfrustrated: イライラしていますapproach: アプローチcollaboration: コラボレーションyielded: 生みましたtechnique: 技術talents: 才能charm: 魅力craft: 書きたいjoint: 一緒に

Akiko lebt in Tokio in selbst gewählter Einsamkeit bis sie ihrer ersten Liebe aus Schulzeiten wiederbegegnet. Plötzlich ist die Welt eine andere, plötzlich türmen sich die Fragezeichen ihrer Biografie. Jan-Philipp Sendker war viele Jahre Korrespondent in den USA und in Asien. Immer wieder spielt Asien in seinen Romanen eine Rolle. Seine Roman-Trilogie über Burma hat er 2021 mit "Die Rebellin und der Dieb" abgeschlossen und erfreute sich internationalem Erfolg. Mit "Akikos stilles Glück" wechselt er den Schauplatz nach Tokio. Über das Schreiben, seine persönlichen Erfolge und Leidenschaften spricht Jan-Philipp Sendker mit Annemarie Stoltenberg in "NDR Kultur à la carte".

Japāniete Akiko Mizoguči Kobi pilsētā atvērusi latviešu amatniecības priekšmetu veikalu, uzrakstījusi un izdevusi jau piecas grāmatas par Latviju, māca kokles spēli, nodibinājusi latviešu tautas mūzikas grupu ar skanīgu nosaukumu “Uzmanību”.  Raidījumā tiekamies ar Latvijas fani Akiko Mizoguči, mūziķi Uldi Cīruli jeb DJ Monsta, kā arī adītāju Sandru Lismani. 

Fluent Fiction - Japanese: Mystical Lights of Arashiyama: A Night of Discovery Find the full episode transcript, vocabulary words, and more:fluentfiction.org/mystical-lights-of-arashiyama-a-night-of-discovery Story Transcript:Ja: 夏の夜、嵐山の竹林は静かで神秘的でした。En: On a summer night, the bamboo grove in Arashiyama was quiet and mysterious.Ja: 竹の間から月の光が差し込み、影が踊るように揺れています。En: Moonlight filtered through the bamboo, casting shadows that swayed as if dancing.Ja: 周囲の寺院から漂う線香の香りが、空気を満たしていました。En: The scent of incense drifted in the air from the surrounding temples.Ja: ちょうどお盆の時期、人々はご先祖様を迎える準備で忙しい中、不思議な光が毎年現れるという噂が広がっていました。En: It was the Obon season, and people were busy preparing to welcome their ancestors, while rumors spread of a mysterious light that appeared every year.Ja: 大学生のヒロシは、この光の正体を探ることに夢中でした。En: Hiroshi, a college student, was fascinated by the mystery of this light.Ja: 彼は民話に興味があり、科学的な説明を見つけようとしていました。En: He had an interest in folklore and was eager to find a scientific explanation.Ja: しかし、幼馴染のアキコはその話に懐疑的でした。En: However, his childhood friend Akiko was skeptical of the story.Ja: 「あれはただの噂だよ、ヒロシ。信じるのは馬鹿らしい」と言います。En: "It's just a rumor, Hiroshi. It's ridiculous to believe it," she said.Ja: 一方、地元のツアーガイドのユミは、昔から語り継がれるこの地の霊的な話を密かに信じていました。En: Meanwhile, Yumi, a local tour guide, secretly believed in the spiritual stories handed down through generations in the area.Ja: ヒロシは結局、竹林に歩を進めることにしました。En: Ultimately, Hiroshi decided to venture into the bamboo grove.Ja: 「君たち、僕と一緒に来ない？」と二人に声をかけます。En: "Won't you two come with me?” he asked them.Ja: ユミは一瞬迷いましたが、「実は私も行ってみたい。ガイドとして、ちゃんと説明できることを確認したいの」と決心します。En: Yumi hesitated for a moment but then made up her mind, saying, "Actually, I'd like to go, too. As a guide, I want to confirm that I can explain it properly."Ja: アキコも、「一人で行かせるわけにはいかない」という言葉を添えて同行を決めました。En: Akiko also decided to join them, adding, "I can't let you go alone."Ja: 三人は暗い竹林を進んでいきました。En: The three of them advanced through the dark bamboo grove.Ja: ヒロシは興奮しながら、「必ず何かわかるはずだ」と自信を持っていました。En: Hiroshi, filled with excitement, confidently stated, "We're bound to discover something."Ja: やがて、不思議な光が現れました。En: Eventually, the mysterious light appeared.Ja: それはふわりと揺れ、彼らの方へと近づいてきたのです。En: It floated and swayed, moving closer to them.Ja: 「何だろう…？」とアキコは少し恐れながらも好奇心でいっぱいになりました。En: "What could it be...?" Akiko said, filled with curiosity despite a hint of fear.Ja: ヒロシは心臓を高鳴らせつつも慎重に観察し、あっと驚きました。「これは珍しい蛍の一種だ！」と叫びます。En: Hiroshi, with his heart pounding, observed carefully and exclaimed in surprise, "It's a rare type of firefly!"Ja: その光る虫たちは、毎年お盆の時期にしか現れない特別な種類だったのです。En: The glowing insects were a special species that only appeared during the Obon season each year.Ja: ヒロシはその発見に満足し、アキコは自然の不思議を少し信じるようになりました。En: Satisfied with his discovery, Hiroshi had found an explanation, and Akiko began to believe a bit in the wonders of nature.Ja: ユミは人々を驚かせることなく、静かに自分の信仰を続けることができました。En: Yumi could quietly continue her beliefs without surprising others.Ja: 竹林の冒険を終え、人々はそれぞれ変わって帰りました。En: After their adventure in the bamboo grove, the three returned home, each changed in some way.Ja: ヒロシは好奇心と科学のバランスを学び、アキコには伝統やミステリーの価値が伝わりました。ユミは自分の役割により自信を持ち、また新しい伝説を生み出しました。En: Hiroshi learned the balance between curiosity and science, Akiko appreciated the value of tradition and mystery, and Yumi gained more confidence in her role and created a new legend.Ja: 風が竹を揺らし、彼らの影を月の光の下に映しながら、夜がまた静かに包み込みました。En: The wind rustled the bamboo, casting their shadows under the moonlight, as the night once again gently enveloped them. Vocabulary Words:grove: 竹林mysterious: 神秘的incense: 線香ancestors: ご先祖様rumors: 噂ridiculous: 馬鹿らしいskeptical: 懐疑的venture: 歩を進めるhesitated: 迷いましたconfirm: 確認したいadvancing: 進んでいきましたexcitement: 興奮curiosity: 好奇心observed: 観察しrare: 珍しいspecies: 種satisfied: 満足しdiscovery: 発見appreciated: 価値が伝わりましたtradition: 伝統confidence: 自信role: 役割rustled: 揺らしshadows: 影enveloped: 包み込みましたscientific explanation: 科学的な説明folklore: 民話spiritual: 霊的なbalancing: バランス

Fluent Fiction - Japanese: Braving the Arctic: Students Unveil Climate Secrets Find the full episode transcript, vocabulary words, and more:fluentfiction.org/braving-the-arctic-students-unveil-climate-secrets Story Transcript:Ja: 北極ツンドラは広大で氷のような風景が広がっていました。En: The Arctic tundra stretched vast and icy, with a landscape that seemed endless.Ja: 草木は低く、地平線は永遠に続くように見えます。En: The vegetation was low, and the horizon appeared to go on forever.Ja: 夏の終わりには、日光がいつまでも続きますが、冷たい風が季節の厳しさを思い出させます。En: At the end of summer, the sunlight lingered, but the cold winds reminded everyone of the harshness of the season.Ja: 弘は環境に熱心な高校生です。En: Hiro is a high school student passionate about the environment.Ja: 彼は北極ツンドラでのフィールドトリップに参加しました。気候変動についての科学プロジェクトのためです。En: He participated in a field trip to the Arctic tundra for a science project on climate change.Ja: 彼のクラスメート、秋子は冷静で分析力があります。しかし、自分の意見を言うのを恐れていました。En: His classmate Akiko is calm and analytical but was afraid to voice her opinions.Ja: 先生のレンは、ユニークな環境で教えることが好きです。しかし、生徒たちの世話に少し圧倒されています。En: Their teacher, Ren, enjoys teaching in unique environments, but he feels a bit overwhelmed taking care of the students.Ja: 弘は十分なデータを集めたいと思っています。しかし、寒さには弱く、集中力を保つのが難しいと感じていました。En: Hiro wanted to gather sufficient data but struggled to maintain concentration due to his susceptibility to the cold.Ja: 一方、秋子は自分の考えを言うことを恐れていました。En: Meanwhile, Akiko feared expressing her thoughts.Ja: 彼女のアイデアはプロジェクトに役立ちますが、伝えられずにいました。En: Her ideas were valuable to the project but remained unspoken.Ja: ある日、彼らは地球温暖化についてのデータを集め始めました。En: One day, they began collecting data on global warming.Ja: 弘は寒さに震えながら、仲間をまとめる決意をしました。En: Shivering from the cold, Hiro resolved to rally his peers.Ja: 「みんな、大丈夫？協力して頑張りましょう！」と彼は声をかけました。En: "Is everyone okay? Let's work together and do our best!" he called out.Ja: 秋子は初めて自分の考えを共有することに決めました。En: For the first time, Akiko decided to share her thoughts.Ja: 「この方法でデータを効率的に集められるかも」と彼女は小さな声で言いました。En: "This method might help us gather data more efficiently," she said in a small voice.Ja: 突然、強い雪嵐が彼らを襲いました。En: Suddenly, a fierce snowstorm struck them.Ja: 彼らはキャンプにこもらなければなりませんでした。En: They had to take shelter in their camp.Ja: しかし、それは気候変動の影響を直接観察するチャンスでもありました。En: However, it also turned out to be a chance to directly observe the effects of climate change.Ja: 弘と秋子は状況をうまく乗り切り、予想しなかったデータを集めることができました。En: Hiro and Akiko managed to navigate the situation skillfully and collected unexpected data.Ja: チームはデータを豊富に集め、説得力のある分析を完成させました。En: The team gathered ample data and completed a compelling analysis.Ja: レン先生からもクラスメートからも高評価を得ました。En: They received high praise from both Mr. Ren and their classmates.Ja: 秋子の貢献は際立ち、彼女の自信を大きく後押ししました。En: Akiko's contributions stood out, greatly boosting her confidence.Ja: 弘は、苦境を乗り切るたくましさとチームワークの重要性を学びました。En: Hiro learned about resilience in adversity and the importance of teamwork.Ja: 秋子は自分の声とアイデアの力を知り、自分の能力に自信を持つようになりました。En: Akiko discovered the power of her voice and ideas, gaining confidence in her abilities.Ja: この経験は彼らを成長させ、次のステップへと導いたのです。En: This experience helped them grow and led them to their next steps. Vocabulary Words:tundra: ツンドラvegetation: 草木horizon: 地平線linger: 続くsusceptibility: 弱さresilience: たくましさadversity: 苦境endless: 永遠に続くcompelling: 説得力のあるanalysis: 分析navigate: 乗り切るfierce: 強いshelter: こもるboosting: 後押しするconfidence: 自信harshness: 厳しさfield trip: フィールドトリップanalytical: 分析力があるoverwhelmed: 圧倒されるconcentration: 集中力rally: まとめるpeers: 仲間unexpected: 予想しなかったample: 豊富なvoice her opinions: 意見を言うmethod: 方法storm: 雪嵐directly observe: 直接観察するsufficient: 十分なstep: ステップ

This episode we're discussing the romance(?) genre(s?) of Yaoi, Danmei, and BL. We talk about tropes, themes, shelving, not understanding fiction from other cultures, and more! Plus: We probably make a bunch of mistakes. You can download the podcast directly, find it on Libsyn, or get it through Apple Podcasts or your favourite podcast delivery system. In this episode Anna Ferri | Meghan Whyte | Matthew Murray

Chase & Timothy talk with Akiko Kurematsu about home cooking, family recipes, and seasonality.  Follow Akiko: https://akikokurematsu.com/ @mothertonguebook on Instagram Follow: Customer Service Podcast on Instagram @customerservicepod  Canoe Club on Instagram & YouTube @shopcanoeclub  ⁠www.shopcanoeclub.com

Feel free to send us a message! What did you think of this movie? Of this episode? Andrew and Scotty get their kaiju on as they discuss "Godzilla Minus One". Scotty is a pretty big Godzilla fan, and Andrew hasn't watched a lot of Japanese Godzilla movies, so this was an interesting discussion. They also read a new review on Apple Podcasts, some answers on Spotify, and welcome a new Patron With Horror from their Patreon! And stay tuned until the end of the episode to find out what Andrew has chosen for their next movie!"Godzilla Minus One" is the 37th film on the Godzilla franchise! It was directed by Takashi Yamazaki and stars Ryunosuke Kamiki as Koichi Shikishima, a kamikaze pilot who backs away from his mission only to come face to face with a giant reptilian creature on a small island. He makes his way back to Tokyo after surviving the attack and deals with his PTSD and survivor's guilt while also caring for a young woman named Noriko and an orphaned baby named Akiko. Soon, a larger, mutated Godzilla makes his way to Tokyo...Support us on Patreon! - https://www.patreon.com/FunWithHorrorPodcastFollow us on social media:Facebook - https://www.facebook.com/groups/396586601815924Twitter - https://twitter.com/funwhorrorInstagram - https://www.instagram.com/fun_with_horror_podcast/FWH + Fangoria collab:For 20% off at the Fango Shop, just enter FUN_WITH_HORROR_PODCAST at checkout!

Morgana is back but sick. Still, it doesn't stop us from returning to Paru Itagaki's unhinged animal kingdom with Beast Complex 2 + 3! We also talk about hot lettuce, Tougen Anki: Legend of the Cursed Blood, Ramen Akaneko, Maru Sankaku Shikaku, and more!!! Send us emails! mangamachinations@gmail.com  Follow us on Twitter! @mangamacpodcast Check out our website! https://mangamachinations.com Check out our YouTube channel! https://www.youtube.com/mangamactv Check out our new commentary channel! https://www.youtube.com/@MangaMacWatches Timestamps: Intro - 00:00:00 American Library Association Conference - 00:08:58 Tougen Anki: Legend of the Cursed Blood - 00:11:24 The Guy She Was Interested In Wasn't a Guy at All - 00:15:37 Unico: Awakening - 00:16:40 The Wicked City - 00:20:05 Ramen Akaneko - 00:28:53 Maru Sankaku Shikaku - 00:31:00 Next Episode Preview - 00:47:54 Beast Complex 2 + 3 - 00:48:43 Outro - 01:16:15 Songs Credits: “Galaxy Groove” by Yarin Primak “Slappy” by Ido Maimon “Whipped Cream” by Steven Beddall “Psychedelic Funkadelic” by Evert Z

Akiko Iwasaki, Ph.D., is a Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University, and an Investigator of the Howard Hughes Medical Institute. She received her Ph.D. from the University of Toronto in Canada and her postdoctoral training from the National Institutes of Health. Her research focuses on the mechanisms of immune defense against viruses at the mucosal surfaces, and the development of mucosal vaccine strategies. She is the co-Lead Investigator of the Yale COVID-19 Recovery Study, which aims to determine the changes in the immune response of people with long COVID after vaccination. Dr. Iwasaki also leads multiple other studies to interrogate the pathobiology of long COVID, both in patients, and through developing animal models of long COVID. Dr. Iwasaki was elected to the National Academy of Sciences in 2018, to the National Academy of Medicine in 2019, to the European Molecular Biology Organization in 2021, and to the American Academy of Arts and Sciences in 2021.

If there's one person you'd want to talk to about immunology, the immune system and Covid, holes in our knowledge base about the complex immune system, and where the field is headed, it would be Professor Iwasaki. And add to that the topic of Women in Science. Here's our wide-ranging conversation.A snippet of the video, Full length Ground Truths videos are posted here and you can subscribe. Ground Truths is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.Transcript with many external link and links to the audio, recorded 30 April 2024 Eric Topol (00:06):Hello, it's Eric Topol and I'm really thrilled to have my friend Akiko Iwasaki from Yale, and before I start talking with Akiko, I just want to mention there aren't too many silver linings of the pandemic, but one for me was getting to know Professor Iwasaki. She is my go-to immunologist. I've learned so much from her over the last four years and she's amazing. She just, as you may know, she was just recently named one of the most influential people in the world by TIME100. [and also recognized this week in TIME 100 Health]. And besides that, she's been elected to the National Academy of Medicine, National Academy of Sciences. She's the president of the American Association of Immunologists and she's a Howard Hughes principal investigator. So Akiko, it's wonderful to have you to join into an extended discussion of things that we have of mutual interest.Akiko Iwasaki (01:04):Thank you so much, Eric, for having me. I equally appreciate all of what you do, and I follow your blog and tweets and everything. So thank you Eric.Eric Topol (01:14):Well, you are a phenom. I mean just, that's all I can say because I think it was so appropriate that TIME recognize your contributions, not just over the pandemic, but of course throughout your career, a brilliant career in immunology. I thought we'd start out with our topic of great interest on Long Covid. You've done seminal work here and this is an evolving topic obviously. I wonder what your latest thoughts are on the pathogenesis and where things are headed.Long CovidAkiko Iwasaki (01:55):Yeah, so as I have been saying throughout the pandemic, I think that Long Covid is not one disease. It's a collection of multiple diseases and that are sort of ending up in similar sets of symptoms. Obviously, there are over 200 symptoms and not everyone has the same set of symptoms, but what we are going for is trying to understand the disease drivers, so persistent viral infection is one of them. There are overwhelming evidence for that theory now, all the way from autopsy and biopsy studies to looking at peripheral blood RNA signatures as well as circulating spike protein and nucleocapsid proteins that are detected in people with Long Covid. Now whether that persistent virus or remnants of virus is driving the disease itself is unclear still. And that's why trials like the one that we are engaging with Harlan Krumholz on Paxlovid should tell us what percentage of the people are suffering from that type of driver and whether antivirals like Paxlovid might be able to mitigate those. If I may, I'd like to talk about three other hypotheses.Eric Topol (03:15):Yeah, I'd love for you to do that.Akiko Iwasaki (03:18):Okay, great. So the second hypothesis that we've been working on is autoimmune disease. And so, this is clearly happening in a subset of people, again, it's a heterogeneous disease, but we can actually not only look at reactogenicity of antibodies from people with Long Covid where we can transfer IgG from patients with Long Covid into an animal, a healthy animal, and really measure outcomes of a pathogenesis. So that's a functional evidence that antibodies in some people with Long Covid is really actually causing some of the damages that are occurring in vivo. And the third hypothesis is the reactivation of herpes viruses. So many of us adults have multiple latent herpes virus family members that are just dormant and are not really causing any pathologies. But in people with Long Covid, we're seeing elevated reactivation of viruses like Epstein-Barr virus (EBV) or Varicella-zoster virus (VZV) and that may again be just a signature of Long Covid, but it may also be driving some of the symptoms that people are suffering from.(04:32):So that's again, we see the signature over and over, not just our group, but multiple other groups, Michael Peluso's group, Jim Heath, and many others. So that's also an emerging evidence from multiple groups showing that. And finally, we think that inflammation that occurs during the acute phase can sort of chronically change some tissue tone. For instance, in the brain with Michelle Monje's team, we developed a sort of localized mild Covid model of infection and showed that changes in microglia can be seen seven weeks post infection even though the virus is completely gone. So that means that inflammation that's established as a result of this initial infection can have prolonged sequence and sequela within the person and that may also be driving disease. And Eric, the reason we need to understand these diseases separately is because not only for diagnostic purposes, but for therapeutic purposes because to target a persistent virus is very different approach from targeting autoantibodies, for example.Eric Topol (05:49):Well, that's great. There's a lot to unpack there as you laid out four distinct paths that could result in the clinical syndrome and sequelae. I think you know I had the chance to have a really fun conversation with Michelle about their joint work that you've done, and she reminded me how she made a cold call to you to start as a collaboration, which I thought was fantastic. Look what that yielded. But yeah, this is fascinating because as I think you're getting at is that it may not be the same pathogenesis in any given individual so that all these, and even others might be operative. I guess maybe I first delve into the antibody story as you're well aware, we see after people get Covid a higher rate of autoimmune diseases crop up, which is really interesting because it seems to rev up self-directed immune response. And this I think many people haven't really noted yet, although obviously you're well aware of this, it's across all the different autoimmune diseases, connective tissue disease, not just one in particular. And it's, as you say, the idea that you could take the blood from a person suffering from Long Covid and give it to an experimental animal model and be able to recapitulate some of the abnormalities, it's really pretty striking. So the question I guess is if you were to do plasmapheresis and try to basically expunge these autoantibodies, wouldn't you expect people to have some symptomatic benefit pretty rapidly or is it just that the process is already far from the initiating step?Akiko Iwasaki (07:54):That's a great question. Plasmapheresis may be able to transiently improve the person if they're suffering from these autoantibody mediated diseases. People have reported, for example, IVIG treatment has dramatically improved their symptoms, but not in everybody. So it's really critical to understand who's suffering from this particular driver and appropriately treat those people. And there are many other very effective therapies in autoimmune disease field that can be repurposed for treating these patients as well.Eric Topol (08:34):The only clinical trial that has clicked so far, interestingly, came out of Hong Kong with different types of ways to manipulate the gut microbiome, which again, you know better than me is a major modulator of our immune system response. What are your thoughts about taking advantage of that way to somehow modulate this untoward immune response in people with this condition?Akiko Iwasaki (09:07):Yeah, so that is an exciting sort of development, and I don't mean to discount the importance of microbiome at all. It's just the drivers that are mentioning are something that can be directly linked to disease, but certainly dysbiosis and translocation of metabolites and microbiome itself could trigger Long Covid as well. So it's something that we're definitely keeping our eyes on. And as you say, Eric, the immune system is in intimate contact with the gut microbiome and also the gut is intimate contact with the brain. So there's a lot of connections that we really need to be paying attention to. So yeah, absolutely. This is a very exciting development.Eric Topol (09:57):And it is intriguing of course, the reactivation of viruses. I mean, we've learned in recent years how important EBV is in multiple sclerosis (MS). The question I have for you on that pathway, is this just an epiphenomena or do you actually think that could be a driving force in some people?Akiko Iwasaki (10:19):Yeah, so that's really hard to untangle in people. I mean, David Putrino and my team we're planning a clinical trial using Truvada. Truvada obviously is an HIV drug, but it has reported antiviral activity to Epstein-Barr virus (EBV) and others. So potentially we can try to interrogate that in people, but we're also developing mouse models that can sort of recapitulate EBV like viral reactivation and to see whether there's any sort of causal link between the reactivation and disease process.Eric Topol (10:57):Right now, recently there's been a bunch of anecdotes of people who get the glucagon-like peptide one (GLP-1) drugs which have a potent anti-inflammatory, both systemic and in the brain. I'd love to test these drugs, but of course these companies that make them or have other interests outside of Long Covid, do you think there's potential for a drug like that?Akiko Iwasaki (11:23):Yeah, so those drugs seem to have a lot of miraculous effects on every disease. So obviously it has to be used carefully because many people with Long Covid have issues with liver functions and other existing conditions that may or may not be conducive to taking those types of GLP-1 agonists. But in subset of people, maybe this can be tried, especially due to the anti-inflammatory properties, it may benefit again, a subset of people. I don't expect a single drug to cure everyone. That would be pretty amazing, but unlikely.Eric Topol (12:09):Absolutely. And it's unfortunate we are not further along in this whole story of clinical trials, testing treatments and applauding your efforts with my friend Harlan there to get into the testing which we had hoped RECOVER was going to do with their more than billion dollars or allocation, which didn't get us too far in that. Now before we leave Long Covid, which we could speak about for hours, I mean it's so darn important because so many people are really out there disabled or suffering on a daily basis or periodically they get better and then get worse again. There's been this whole idea that, oh, it's going away and that reinfections don't pose a threat. Maybe you could straighten that story out because I think there seems to be some miscues about the risk of Long Covid even as we go along with the continued circulating virus.Akiko Iwasaki (13:11):Right, so when you look at the epidemiological evidence of Long Covid, clearly in the beginning when we had no vaccines, no antivirals, no real good measure against Covid, the incident of developing Long Covid per infection was higher than a current date where we do have vaccines and Omicron may have changed its property significantly. So if you compare, let's say the Delta period versus Omicron period, there seems to be a reduced risk per infection of Long Covid. However, Omicron is super infectious. It's infected millions of people, and if you look at the total number of people suffering from Long Covid, we're not seeing a huge decline there at all because of the transmissibility of Omicron. So I think it's too early for us to say, okay, the rates are declining, we don't need to worry about it. Not at all, I think we still have to be vigilant.(14:14):We need to be up to date on vaccines and boosters because those seem to reduce the risk for Long Covid and whether Paxlovid can reduce the rate of Long Covid at the acute phase for the high risk individual, it seems to be yes, but for people who are not at high risk may or may not be very effective. So again, we just need to be very cautious. It's difficult obviously, to be completely avoiding virus at this time point, but I think masking and anything you can do, vaccination boosters is going to be helpful. And a reinfection does carry risk for developing Long Covid. So that prior infection is not going to prevent Long Covid altogether, even though the risk may be slightly reduced in the first infection. So when you think about these risks, again we need to be cognizant that reinfection and some people have multiple infections and then eventually get Long Covid, so we're just not safe from Long Covid yet.Nasal Vaccines and Mucosal ImmunityEric Topol (15:24):Right. No, I think that's the problem is that people have not acknowledged that there's an ongoing risk and that we should continue to keep our guard up. I want to applaud you and your colleagues. You recently put out [Yale School of Public Health] this multi-panel about Covid, which we'll post with this podcast that gave a lot of the facts straight and simple diagrams, and I think this is what you need is this is kind of like all your threads on Twitter. . They're always such great educational ways to get across important information. So now let's go onto a second topic of great mutual interest where you've also been a leader and that's in the mucosal nasal vaccine story. I had the privilege of writing with you a nice article in Science Immunology back in 2022 about Operation Nasal Vaccine, and unfortunately we don't have a nasal vaccine. We need a nasal vaccine against Covid. Where do we stand with this now?Akiko Iwasaki (16:31):Yeah, so you're right. I mean nasal vaccines, I don't really know what the barrier is because I think the preclinical models all support the effectiveness against transmission and infection and obviously disease. And there is a White House initiative to support rapid development of next generation vaccine, which includes mucosal vaccine, so perhaps that's sort of pushing some of these vaccine candidates forward. You're probably more familiar than me about those kinds of events that are happening. But yeah, it's unfortunate that we don't have an approved mucosal booster vaccine yet, and our research has shown that as simple as a spray of recombinant spike protein without any adjuvants are able to restimulate immune response and then establish mucosal immunity in the nasal cavity, which goes a long way in preventing infection as well as transmission. So yeah, I mean I'm equally frustrated that things like that don't exist yet.The Neomycin and Neosporin SurpriseEric Topol (17:52):Well, I mean the work that you and many other groups around the world have published on this is so compelling and this is the main thing that we don't have now, which is a way to prevent infection. And I think most of us would be very happy to have a spray that every three or four months and gave us much higher levels of protection than we're ever going to get from shots. And your whole concept of prime and spike, I mean this is something that we could have had years ago if there was a priority, and unfortunately there never has been. Now, the other day you came with a surprise in a paper on Neomycin as an alternate or Neosporin ointment. Can you tell us about that? Because that one wasn't expected. This was to use an antibiotic in a way to reduce Covid and other respiratory virus.Akiko Iwasaki (18:50):Right. So yeah, that's a little known fact. I mean, of course widespread use of antibiotics has caused some significant issues with resistance and so on. However, when you look at the literature of different types of antibiotics, we have reported in 2018 that certain types of antibiotics known as aminoglycoside, which includes Neosporin or neomycin, has this sort of unintended antiviral property by triggering Toll-like receptor 3 in specialized cell types known as conventional dendritic cell type 1. And we published that for a genital herpes model that we were working on at the time. But because it's acting on the host, the Toll-like receptor 3 on the host cell to induce interferon and interferon stimulated genes to prevent the replication of the virus, we knew that it could be pan-viral. It doesn't really matter what the virus is. So we basically leverage that discovery that was made by a postdoc Smita Gopinath when she was in the lab to see if we can use that in the nasal cavity.(20:07):And that's what Tianyang Mao, a former graduate student did, in fact. And yeah, little spray of neomycin in the nose of the mice reduce this infection as well as disease and can even be used to treat shortly after the infection disease progress and using hamster models we also showed that hamsters that are pretreated with neomycin when they were caged with infected hamsters, the transmission rate was much reduced. And we also did with Dr. Charles Dela Cruz, a small clinical trial, randomized though into placebo and Neosporin arms of healthy volunteers. We asked them to put in a pea size amount of Neosporin on a cotton swab into the nose, and they were doing that twice a day for seven days. We measured the RNA from the nose of these people and indeed see that more than half the participants in the Neosporin group had elevated interferon stimulated genes, whereas the control group, which were given Vaseline had no response. So this sort of shows the promise of using something as generic and cheap as Neosporin to trigger antiviral state in the nose. Now it does require a much larger trial making sure that the safety profiles there and effectiveness against viral infection, but it's just a beginning of a story that could develop into something useful.New Frontiers in Immunology and Tx CellsEric Topol (21:51):Yeah, I thought it was fascinating, and it does bring up, which I think has also been underdeveloped, is our approaches for interferon a frontline defense where augmenting that, just getting that exploiting the nasal mucosa, the entry site, whether it be through that means or of course through even more potent a nasal vaccine, it's like a missing, it's a hole in our whole defense of against this virus that's led to millions of people not just dying, but of course also sick and also with Long Covid around the world. So I hope that we'll see some progress, but I thought that was a really fascinating hint of something to come that could be very helpful in the meantime while we're waiting for specific nasal vaccines. Now added to all these things recently, like last week you published a paper in Cell with your husband who's in the same department, I think at Yale. Is that right? Can you tell us about that and this paper about the whole new perspectives in immunology?Akiko Iwasaki (23:05):Yeah, so my husband Ruslan Medzhitov is a very famous immunologist who's in the same department, and we've written four or five review and opinion pieces together over the years. This new one is in Cell and it's really exploring new perspectives in immunology. We were asked by the editors to celebrate the 50th anniversary of the Cell journal with a perspective on the immune system. And the immune response is just a beautiful system that is triggered in response to specific pathogens and can really provide long-term or even sometimes lifelong immunity and resistance against pathogens and it really saves our lives. Much has been learned throughout the last 20, 30 years about the innate and adaptive immune system and how they're linked. In this new perspective, we are trying to raise some issues that the current paradigm cannot explain properly, some of the mysteries that are still remaining in the immune system.(24:22):And we try to come up with new concepts about even the role of the immune system in general. For instance, is the immune system only good for fighting pathogens or can it be repurposed for conducting normal physiology in the host? And we came up with a new subset of T-cells known as, or we call it Tx cells, which basically is an interoceptive type of T-cells that monitor homeostasis in different tissues and are helping with the normal process of biology as opposed to fighting viruses or bacteria or fungi. But these cells, when they are not appropriately regulated, they are also the source of autoimmune diseases because they are by design reactive against auto antigens. And so, this is a whole new framework to think about, a different arm of the immune function, which is really looking inside of our body and not really fighting against pathogens, but we believe these cells exist, and we know that the counterpart of Tx cells, which is the T regulatory cells, are indeed well known for its physiological functions. So we're hoping that this new perspective will trigger a new set of approaches in the field to try to understand this interceptive property of T-cells.Eric Topol (25:59):Yeah, well, I thought it was fascinating, of course, and I wanted to get into that more because I think what we're learning is this immune system not only obviously is for cancer whole. We're only starting to get warmed up with immunotherapy where checkpoint inhibitors were just the beginning and now obviously with vaccines and all these different ways that we can take the CAR-T cells, engineered T-cells, take the immune system to fight cancer and potentially to even use it as a way to prevent cancer. If you have these, whether it's Tx or Tregs or whatever T-cells can do this. But even bigger than that is the idea that it's tied in with the aging process. So as you know, again, much more than I do, our senescent immune cells are not good for us. And the whole idea is that we could build immune resilience if we could somehow figure out these mysteries that you're getting at, whereby we get vulnerable just as we were with Covid. And as we get older, we get vulnerable to not just infections, but everything going wrong, whether it's the walls of our arteries or whether it's the cancer or the immunity that's going on in our brain for Alzheimer's and neurodegenerative diseases. How can we fix the immune system so that we age more healthilyThe Immune System and Healthy Aging Akiko Iwasaki (27:37):Oh yeah. A lot of billionaires are also interested in that question and are pouring money into this question. It's interesting, but when you think about the sort of evolutionary perspective, we humans are only living so long. In the very recent decades, our life expectancy used to be much shorter and all we had to survive was to reproduce and generate the next progeny. But nowadays, because of this amazing wealth and health interventions and food and everything else, we're just living so much longer than even our grandparents. The immune system didn't evolve to deal with such one to begin with. So we were doing fine living up to 30 years of age or whatever. But now that we're living up to a hundred years, the immune system isn't really designed to keep up with this kind of stressors. But I think you're getting at a very important kind of more engineering questions of how do we manipulate the immune system or rejuvenate it so that we can remain healthy into the later decades? And it is well known that the immune system itself ages and that our ability to produce new lymphocytes, for example, decline over time and thymus that is important for T-cell development shrinks over time. And so anatomically it's impossible to help stop that process. However, is there a way of, for example, transferring some factors or engineering the immune cells to remain healthy and even like hematopoiesis itself can be manipulated to perhaps rejuvenate the whole immune system in their recent papers showing that. So this is a new frontier.Eric Topol (29:50):Do you think that some point in the future, we'll ex vivo inject Yamanaka factors into these cell lines and instead of this idea that you know get young plasma to old folks, and I mean since we don't know what's in there and it doesn't specifically have an effect on immune cells, who knows how it's working, but do you foresee that that might be a potential avenue going forward or even an in vivo delivery of this?Akiko Iwasaki (30:22):Yeah, it's not impossible, right? There are really rapidly evolving technologies and gene therapies that are becoming online. So it's not impossible to think about engineering in situ as you're suggesting, but we also have to be certain that we are living longer, but also healthy. So we do have to not only just deal with the aging immune system, but preventing neurodegenerative diseases and so on. And the immune system may have a role to play there as well. So there's a lot of, I mean, I can't think of a non-genetically mediated disease that doesn't involve the immune system.Eric Topol (31:03):Sure. No, I mean, it's just, when I think about this, people keep talking about the digital era of digital biology, but I actually think of it more as digital immunobiology, which is driving this because it's center stage and in more and more over time. And the idea that I'm concerned about is that we could rejuvenate the relevant immune cells or the whole immune response, but then it's such a delicate balance that we could actually wind up with untoward, whether it's autoimmune or overly stimulated immune system. It's not such a simple matter, as I'm sure you would agree. Now, this gets me to a broader thing which you've done, which is a profound contribution in life science and medicine, which is being an advocate for women in science. And I wonder if you could speak to that because you have been such a phenomenal force propelling the importance of women in science and not just doing that passively, but also standing up for women, which is being an activist is how you get things to change. So can you tell us about your thoughts there?An Activist for Women in ScienceAkiko Iwasaki (32:22):Yeah, so I grew up in Japan, and part of the reason I left Japan at the age of 16 was that I felt very stifled because of the societal norm and expectation of what a woman should be. And I felt like I didn't have the opportunity to develop my skills as a scientist remaining in Japan. And maybe things have changed over the years, but at the time when I was growing up, that's how I felt. And so, I was very cognizant of biases in society. And so, in the US and in Canada where I also trained, there's a lot less barrier to success, and we are able to do pretty much anything we want, which is wonderful, and that's why I think I'm here. But at the same time, the inequity still exists, even in pay gaps and things like that that are easy to fix but are still kind of insidious and it's there.(33:32):And Yale School of Medicine has done a great job partly because of the efforts of women who spoke up and who actually started to collect evidence for pay gap. And now there's very little pay gap because there's active sort of involvement of the dean and everyone else to ensure equity in the medical school. But it's just a small segment of the society. We really need to expand this to other schools and making sure that women are getting paid equally as men in the same ranks. And also, I see still some sexual harassment or more just toxic environment for people in general in academia. Some PIs get away with a lot of behavior that's not conducive to a healthy environment, so I have written about that as well and how we can have antidotes for such toxic environments. And it really does require the whole village to act on it. It's not just one person speaking up. And there should be measures placed to make sure that those people who does have this tendency of abusive behavior that they can get training and just being aware of these situations and corrective behavior. So I think there's still a lot of work left in academia, but things have obviously improved dramatically over the last few decades, and we are in a very, very good place, but we just have to keep working to achieve true equity.Why Don't We Have Immunome Check-Ups?Eric Topol (35:25):Well applauding your efforts for that, and I'm still in touch with that. We got a ways to go, and I hope that we'll see steady and even more accelerated and improvement to get to parity, which is what it should be. And I really think you've been a model for doing this. It isn't like you aren't busy with everything else, so to fit that in is wonderful. In closing up, one of the things that I wonder about is our ability to assess back to the immune system for a moment isn't what it should be. That is we do a CBC and we have how many lymphocytes, how many this, why don't we have an immunome, why doesn't everybody serially have an immune system checkup? Because that would tell us if we're starting to go haywire and then maybe hunt for reactivated viruses or what's going on. Do you foresee that we could ever get to a practical immunome as we go forward? Because it seems like it's a big missing link right now.Akiko Iwasaki (36:33):Yeah, I think that's a great idea. I mean, I'll be the first one to sign up for the immunome.Eric Topol (36:40):But I'm depending on you to make it happen.Akiko Iwasaki (36:44):Well, interestingly, Eric, there are lots of amazing technologies that are developed even during the pandemic, which is monitoring everything from antibody reactivity to reactivated viruses to the cytokines to every cell marker you can imagine. So the technologies out there, it's just I think a matter of having the right set of panels that are relatively affordable because some of these things are thousands of dollars per sample to analyze, and then of course clinical validation, something that's CLIA approved, and then we can start to, I guess the insurance company needs to also cover this, right? So we need to demonstrate the benefit to health in the long run to be able to afford this kind of immunome analysis. But I think that very wealthy people can already get this done.Eric Topol (37:43):Yeah, well, we want to make it so it's a health equity story, not of course, only for the crazy ones that are out there that are taking 112 supplements a day and whatnot. But it's intriguing because I think we might be able to get ahead of things if we had such an easy means. And as you said during the pandemic, for example, my friends here in La Jolla at La Jolla Immunology did all kinds of T-cell studies that were really insightful and of course done with you and others around the country and elsewhere to give us insights that you didn't get just from neutralizing antibodies. But it isn't something that you can get done easily. Now, I think this immunome hopefully will get us to another level in the future. One of the most striking things I've seen in our space clinically before wrapping up is to take the CD19 CAR T therapies to deplete the B cells of people with lupus, systemic sclerosis and other conditions, and completely stop their autoimmune condition. And when the B cells come back, they're not fighting themselves. They're not self-directed anymore. Would you have predicted this? This seems really striking and it may be a clue to the kind of mastering approaches to autoimmune diseases in the future.Akiko Iwasaki (39:19):Yeah, absolutely. So for multiple sclerosis, for example, where B cells weren't thought to be a key player by doing anti-CD20 depletion, there's this remarkable clinical effects. So I think we can only find the answer experimentally in people when they do these clinical trials and show this remarkable effects. That's when we say, aha, we don't really understand immunology. You know what I mean? That's when we have to be humble about what we think we understand. We really don't know until we try it. So that's a really good lesson learned. And these may be also applicable to people with autoimmune phenotype in Long Covid, right? We may be able to benefit from similar kinds of depletion therapy. So I think we have a lot to learn still.Eric Topol (40:14):Yeah, that's why, again, going back to the paper you just had in Cell about the mysteries and about some new ideas and challenging the dogma is so important. I still consider the immune system most complex one in the body by far, and I'm depending on you Akiko to unravel it, not to put any weight on your shoulders. Anyway, this has been so much fun. You are such a gem and always learning from you, and I can't thank you enough for all the work. And the fact is that you've got decades ahead of you to keep building on this. You've already done enough for many people, many scientists in your career, and I know you'll keep going. So we're all going to be following you with great interest in learning from you on a frequent basis. And I hope we'll build on some of the things we've talked about like a Long Covid treatment, treatments that are effective nasal vaccines, maybe even some dab of Neosporin, and keep on the momentum we've had with the understanding of the immune system, and finally, someday achieving the true parity of gender and science. And so, thank you for all that you do.Akiko Iwasaki (41:35):Thank you so much, Eric.************************CreditsHeadshot photo credits by Robert Lisak, Yale School of MedicineMy producer for Ground Truths is Jessica Nguyen, Scripps Research and our technical support for audio/video is by SInjun Balabanoff at Scripps Research.I hope you found the spot informative. Please share itThe Ground Truths newsletters and podcasts are all free, open-access, without ads.Voluntary paid subscriptions all go to support Scripps Research. Many thanks for that—they greatly helped fund our summer internship programs for 2023 and 2024.Note: you can select preferences to receive emails about newsletters, podcasts, or all I don't want to bother you with an email for content that you're not interested in.Comments are welcome from all subscribers. Get full access to Ground Truths at erictopol.substack.com/subscribe

En este episodio nos acompaña Akiko, una intérprete que vive en Japón. Después de pasar un tiempo en España y enamorarse del idioma, Akiko ahora utiliza el español diariamente en su trabajo, traduciendo para los acusados hispanohablantes en las cárceles japonesas. Acompáñanos para conocer más sobre su experiencia y cómo el español se ha convertido en una parte esencial de su vida profesional. Como siempre vas a escuchar muchas expresiones nuevas que vas a poder aprender gracias a la guía de vocabulario y las flashcards. ¡Aprende mucho y disfruta de la conversación!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Mis cursos online: ⁠⁠⁠⁠⁠⁠⁠⁠Español PRO - Advanced Spanish⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Español Ágil - Intermediate Spanish⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Español Claro - Upper-beginner Spanish⁠⁠⁠⁠⁠⁠⁠ Te recomiendo usar la guía de vocabulario antes de escuchar el episodio, y si lo necesitas también tienes disponibles la transcripción gratuita y las flashcards de vocabulario. Advanced Spanish Podcast with Free Transcript & Vocabulary Flashcards⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠www.spanishlanguagecoach.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - Aprende español escuchando contenido natural con conversaciones para estudiantes de español de nivel avanzado con transcripción. Presentado por Spanish Language Coach (César). ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram Spanish Language Coach⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube Channel⁠⁠⁠⁠⁠⁠⁠ --- Send in a voice message: https://podcasters.spotify.com/pod/show/advanced-spanish-podcast/message

Dive into the inspiring journey of Akiko Kawaguchi, a true pioneer in the Japanese legal world. Akiko shares her groundbreaking path of becoming the first Japanese qualified lawyer at Mitsubishi Corporation. In this episode, Akiko reflects on the historical events that shaped her pursuit of justice and logic, her courageous leap into the blue ocean of in-house counsel, and her belief in the transformative power of young minds. Tune in to discover how Akiko's passion for curiosity, continuous learning and embracing new challenges is shaping the future of law. If you enjoyed this episode and it inspired you in some way, we'd love to hear about it and know your biggest takeaway. Head over to Apple Podcasts to leave a review and we'd love it if you would leave us a message here! In this episode you'll hear: How Akiko became the first ever Japanese lawyer at a Japanese trading company The way Akiko took charge of her career for the benefit of Mitsubishi by leaving for another position Bringing about change in Chiyoda Corporation  Starting the organisations and networks she needed, many of which you may have heard of!  Her favourite book and other fun facts  About Akiko Akiko Kawaguchi is Assistant Division Director, Legal & Corporate Affairs Division for Chiyoda Corporation, a global engineering company headquartered in Yokohama, Japan. Akiko holds an LL.B. from Hitotsubashi University (1996) and an LL.M. from Columbia Law School (2005), with Harlan Fiske Stone Scholars. She is a licensed attorney admitted to practice in Japan (since 1999) and in New York, USA (since 2006). Akiko began her professional career in 1999 as the first Japanese qualified in-house counsel at Mitsubishi Corporation, so-called sogo shosha, unique corporate model in Japan to cover broader business “from ramen to rocket,” where she supported local and international business transactions and disputes. In 2019 while working at Mitsubishi Corporation, Akiko was heavily involved in negotiation and implementation of Chiyoda Corporation's revival plan and then she was seconded to Chiyoda Corporation to directly support them. While the work is tough, she enjoys new challenge covering legal, compliance, corporate governance, IR, PR and sustainability, among others. Akiko has been actively involved in the Japan Legal community and has engaged in numerous activities to develop the capabilities of those who have legal background for them to break the silo to fly to higher sky. As one of the first penguins as Japanese in-house counsel, she was the founding member of the Japan In-house Lawyers Association (JILA). In 2021, she co-launched the Japanese Legal Operations Study Group to release legal operations framework “CORE8.” She is also the founding member of CLOC Japan Shared Interest Group. In 2023, she co-launched the Strategic Legal Governance Study Group with reputable Japanese companies' GCs and chairs its subcommittee to explore the corporate function necessary to operate the company in the view of the management and to take necessary action.  Outside of work, Akiko enjoys visiting various libraries and bookstores, strolling around the neighborhood (“wonder wander” according to Stanford school) and listening to rock music.  Connect with Akiko LinkedIn: https://www.linkedin.com/in/akiko-kawaguchi-b24b8b100/  Links Bar Jiro: https://r.gnavi.co.jp/7fa704yu0000/  JILA: https://jila.jp/eng/  CLOC Japan interest group https://cloc.org/  Kim Jiyoung, Born 1982 https://www.amazon.co.jp/-/en/Cho-Nam-Joo/dp/1471184285  Connect with Catherine  Linked In https://www.linkedin.com/in/oconnellcatherine/ Instagram: https://www.instagram.com/lawyeronair YouTube: https://youtube.com/@lawyeronair 

What causes long COVID? Is long COVID dangerous? Who is most likely to get long COVID? Any pediatric long COVID news? What can be done for long term COVID? Our guest is Akiko Iwasaki, PhD, Sterling Professor of Immunobiology at Yale University. American Medical Association CXO Todd Unger hosts.

This week we talk about SPY X FAMILY CODE: WHITE, She Likes Gays, but Not Me, Parasyte: The Grey, and more! Then, we examine three episodes of Manben to see how Kazuhiro Fujita, Akiko Higashimura, and Shin'ichi Sakamoto create manga!!! We're doing a manga giveaway for our upcoming 500th episode! You can win a bundel of Panorama of Hell, Invisible Parade, From This Flame, and Children of Mu-Town! To enter, write a review for Manga Machinations, then email us (mangamachinations@gmail.com) with the subject title "500 giveaway" and tell us where the review is! Send us emails! mangamachinations@gmail.com  Follow us on Twitter! @mangamacpodcast Check out our website! https://mangamachinations.com Check out our YouTube channel! https://www.youtube.com/mangamactv Check out our new commentary channel! https://www.youtube.com/@MangaMacWatches Timestamps: Intro, Episode 500 Giveaway - 00:00:00 SPY X FAMILY CODE: WHITE - 00:07:11 She Likes Gays, but Not Me - 00:15:32 Delicious in Dungeon - 00:25:59 Parasyte: The Grey - 00:29:14 *SPOILERS* Parasyte: The Grey - 00:32:08 En mo Yukari mo - 00:39:53 Next Episode Preview - 00:45:18 Akiko Higashimura - 00:48:19 Kazuhiro Fujita - 01:06:54 Shin'ichi Sakamoto - 01:22:55 Final thoughts - 01:43:13 Outro - 01:48:54 Songs Credits: “Galaxy Groove” by Yarin Primak “Slappy” by Ido Maimon “Whipped Cream” by Steven Beddall “Psychedelic Funkadelic” by Evert Z

Welcome to episode 106 of Holly Jolly X'masu! In this episode, I talk about Akiko's 2017 album, “Have Yourself A Merry Little Christmas.” I hope you enjoyed this second episode about Akiko. “Have Yourself A Merry Little Christmas” has really grown on me since getting it, and while working on this episode. It's a fine album with some great performances, and one I'll be listening to more in the future. Join me back here next week for my special April 1st episode. I'll be talking about the 2008 album, “Whistle Christmas!” by Whistle Man. It's a unique album you're sure to enjoy. Then join me on April 6th for my Pro Wrestling Spectacular. This year is Wrestlemania LV. It's the biggest wrestling event of the year and in conjunction with that, I'll be covering the Christmas albums from the Destroyer and Thunder Sugiyama. I have a poll running, so click here to listen to samples from each of the albums and vote on which wrestler you feel deserves to be crowned the Christmas Heavyweight Champion. This listen in to hear the results. As always, any feedback on this episode would be appreciated. If have any suggestions, or if you'd like to recommend a song or album for a future episode, drop me a line and let me know. Remember, I've added a button to my Ko-fi page. If you'd like to support me one cup of coffee at a time, a donation is only $3. I've also opened a Redbubble store. I only have a couple designs up, but keep an eye on it as I'll be trying to add more. Half of any proceeds or donations received will be donated to support the people of Ukraine, while the rest will be used to purchase new Japanese Christmas music to review for future episodes. You can also find me on Facebook, Instagram and Twitter. And if you get a chance, leave me a review on iTunes. Thanks!

In this captivating episode of the Wine Crush Podcast Season 7, Episode 2, host Heidi Moore whisks us away on a global journey that highlights the diverse and rich tapestry of winemaking. Through engaging conversations with winemakers from the Willamette Valley and beyond, this episode delves deep into not just the intricacies of crafting wine, but also the personal narratives that define the essence of each vineyard.We begin with Mark from Domain 524, whose fascinating story traverses continents, from the lush vineyards of France to the flourishing wine country of Oregon. Mark's winemaking voyage is a testament to the profound influence of cultural heritage and personal experiences on the craft of winemaking. Growing up with summers in France and later embarking on winemaking in Oregon, Mark's narrative beautifully encapsulates how the diversity of experiences and the richness of tradition interlace to create exceptional wines. Through engaging tales of selecting grape clones, adapting to Oregon's climate, and the inspiration behind his wine labels, Mark's journey offers a deep dive into the heart and soul behind Domain 524.In the heart of the episode, we transition to a delightful wine tasting session. This interlude not only serves as a sensory exploration of Oregon's wine diversity but also beautifully bridges the stories of our guests, underscoring the shared passion and distinctive philosophies that shape their winemaking practices.The episode culminates with Akiko and Chris from Shiba Wichern Cellars, whose remarkable journey from Germany, with stops in Japan and Virginia, eventually led them to Oregon. This duo's story is a harmonious blend of love, adventure, and the pursuit of winemaking excellence across borders. With backgrounds that span from beer to wine and continents from Asia to North America and Europe, Akiko and Chris's adventures underscore the universal appeal of winemaking and the unique paths that lead to the vineyard. Their thoughtful approach to embracing Oregon's terroir, coupled with their innovative spirit and dedication to producing distinct blends, reveals the depth of their commitment to contributing to Oregon's wine legacy.This episode of the Wine Crush Podcast transcends the traditional discussions of winemaking by weaving a narrative that celebrates the human element behind every bottle. From Mark's intimate connection to his French heritage and Oregon's land to Akiko and Chris's cross-continental love story underscored by their shared passion for winemaking, listeners are taken on an immersive journey that explores the profound connections between culture, personal journey, and the art of wine.Pour yourself a glass, and let's celebrate the stories of winemakers who remind us that behind every bottle lies a world of stories, waiting to be uncorked.

Welcome to episode 105 of Holly Jolly X'masu! In this episode, I talk about Akiko's 2007 album, “A White Album.” I hope you enjoyed “A White Album.” Japanese Jazz from the 1960s was one of the main reasons I started collecting, but a lot of fantastic Christmas Jazz albums have come out of Japan over the past twenty years as well. It's always fun discovering something new. Join me back here on the 25th for Akiko's second Christmas album, “Have Yourself A Merry Little Christmas.” It features more stripped-down arrangements and puts a lot more focus on Akiko's vocals. It's another great album you're sure to enjoy. As always, any feedback on this episode would be appreciated. If have any suggestions, or if you'd like to recommend a song or album for a future episode, drop me a line and let me know. Remember, I've added a button to my Ko-fi page. If you'd like to support me one cup of coffee at a time, a donation is only $3. I've also opened a Redbubble store. I only have a couple designs up, but keep an eye on it as I'll be trying to add more. Half of any proceeds or donations received will be donated to support the people of Ukraine, while the rest will be used to purchase new Japanese Christmas music to review for future episodes. You can also find me on Facebook, Instagram and Twitter. And if you get a chance, leave me a review on iTunes. Thanks!

Discover how Joshua Jones (CEO and Founder of QuantHub and TedX speaker) started and sold several companies, when he realized that "culture eats strategy for breakfast", and what he shares about the state of Alabama's approach to micro-learning! (16 minute episode). ============================================= CEO Blindspots® Podcast Guest: Joshua Jones ⁠ Joshua Jones is the CEO of QuantHub, a global data literacy and upskilling software company. QuantHub works with individuals and Fortune 500 companies alike to train tomorrow's workforce with data and AI skills.  Prior to his role at QuantHub, Jones was founder and CEO of StrategyWise, an award-winning data science and AI consulting firm. StrategyWise provided data science strategy to global firms ranging from Samsung and Toshiba to Southern Company and Chick-Fil-A. StrategyWise was recognized as one of America's fastest-growing companies three years in a row on the Inc 5000.  A lifelong entrepreneur, Jones's career experience has spanned 6 startups, 40 countries and 7 languages. He has been quoted by Forbes, CIO.com, the Atlanta Business Chronicle, and Entrepreneur Magazine, and is a TEDx alum and regular speaker and lecturer in universities and conferences across the US.    He received his Master of Business Administration at Emory University's Goizueta Business School and his Bachelor of Science in Business Administration from the University of Alabama. He and his wife, Akiko, live with their 3 girls in the United States. For more information about QuantHub; https://www.quanthub.com/ To receive a free data skills assessment; https://www.quanthub.com/data-skills-test/ ======================================== CEO Blindspots® Podcast Host: Birgit Kamps. Birgit's professional experience includes starting and selling an “Inc. 500 Fastest Growing Private Company” and a “Best Company to Work for in Texas”, and serving as a Board Member with various companies. She is able to help investors and executives quickly discover blind spots holding their organization back, and accelerate leadership effectiveness. In addition, Birgit is the host of the CEO Blindspots® Podcast which was recognized for having the “biggest listener growth” in the USA by 733%, and most recently for having the "top 1.5% global podcast" ranking in its category; ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.ceoblindspots.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ To ask questions about this or one of the 200+ other CEO Blindspots® Podcast episodes, send an email to⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠birgit@ceoblindspots.com⁠

Kicking off Season 5 with a deep dive into the King of Monsters.  Godzilla expert & author of "Godzilla On My Mind" Dr. William (Bill) Tsutsui joins the Krewe to discuss the Godzilla franchise, its roots, its impact in Japan, & how it became the global phenomenon it is today. Get in touch with your inner kaiju and learn more about your favorite giant reptilian monster!------ About the Krewe ------The Krewe of Japan Podcast is a weekly episodic podcast sponsored by the Japan Society of New Orleans. Check them out every Friday afternoon around noon CST on Apple, Google, Spotify, Amazon, Stitcher, or wherever you get your podcasts.  Want to share your experiences with the Krewe? Or perhaps you have ideas for episodes, feedback, comments, or questions? Let the Krewe know by e-mail at kreweofjapanpodcast@gmail.com or on social media (Twitter: @kreweofjapan, Instagram: @kreweofjapanpodcast, Facebook: Krewe of Japan Podcast Page, TikTok: @kreweofjapanpodcast, LinkedIn: Krewe of Japan LinkedIn Page, Blue Sky Social: @kreweofjapan.bsky.social, & the Krewe of Japan Youtube Channel). Until next time, enjoy!------ Support the Krewe! Offer Links for Affiliates ------Use the referral links below & our promo code from the episode (timestamps [hh:mm:ss] where you can find the code)!Liquid IV Offer Link  to save 20% Off your Entire Order! (00:01:06)Zencastr Offer Link - Use my special link to save 30% off your 1st month of any Zencastr paid plan!  (52:26:00)------ Bill Tsutsui Links ------Bill Tsutsui's WebsiteGodzilla On My Mind on AmazonBill Tsutsui x Godzilla Music Video------ JSNO Upcoming Events ------JSNO Event Calendar2024 Matsue-New Orleans Sister City Exchange Program Application

Today, we'll be discussing Episode 8 of Gyeongseong Creature, the hit K Drama on Netflix starring Park Seo-joon as Jang Tae-sang, Han So-hee as Yoon Chae-ok, Wi Ha-hun as Kwon Jun-taek, Kim Soo-hyun as Lady Maeda, Ji Woo as Myeong-ja, Jo Han-chul as Yoon Joon-won, and Kim Hae-sook as Nawol daek. We discuss:How Jang Tae-sang was able to escape from Ongseong Hospital by getting the better of the Japanese soldier and holding up Lady Maeda to let him leave with her out of the hospital.Lady Maeda's motivations for nursing Jang Tae-sang back to health.Lady Maeda calling Seishin, the creature, sensei or teacher.Commissioner Ishikawa confronting his wife about what is happening at Ongseong Hospital and what she did to Akiko.How we're learning that Lady Maeda is the silent power behind what happens in Gyeongseong.How Jang Tae-sang negotiated with Ishikawa for the release of the Bonjeong merchants.How Mr. Gu was tortured and now we understand Mrs. Nawol's warning about betraying your loved ones with faced with torture.How Jang  Tae-sang and Yoon Chae-ok are reunited and their hug said so much.How Jang Tae-sang and Yoon Chae-ok are able to steal a moment of happiness together while buying dumplings but it doesn't last long.How Myeong-ja has been on a killing spree through Gyeongseong and now Ishikawa knows she's the murderer responsible for killing people and eating their brains.How Yoon Joong-won, Yoon Chae-ok's father, now knows what happened to his wife.The K Drama elements in this episode, including: crying, lots of triangles involving Lady Maeda, Jang Tae-sang's confession to Yoon Chae-ok, umbrella scene, and JTS pulling YCO out of the way of a speeding car when they're chasing Myeong-ja.What we think of the title of the episode: Awakening, between Justification and Excuse.What happened to Unit 731 after the war.The shows we're watching now and the shows we're considering for Season 7 of K Drama Chat!ReferencesThe Na peopleWhat happened to Unit 731?Does Torture Work?Unit 731 on WikipediaJapan discloses details of notorious chemical warfare divisionhttps://unit731.orgDetails of the atrocities committed by the Japanese

Da Kagawa a Piacenza: Il viaggio di Akiko tra amore, italiano e multiculturalità in Italia.Sono tantissimi gli studenti della Scuola Leonardo da Vinci che, per un motivo o per l'altro, scelgono di cambiare completamente la loro vita trasferendosi in Italia. Oggi conosciamo Akiko, una ragazza giapponese che ha studiato nella scuola di Milano diversi mesi tra il 2019 e il 2021, e che si è trasferita in Italia per seguire il cuore. Infatti, ormai vive a Piacenza da 4 anni insieme al suo compagno italiano.In questa puntata ascolteremo la sua storia, alcuni aneddoti sul suo percorso italiano e cosa ama di più dell'Italia.A lei è dedicata anche l'intervista che potete leggere sul nostro blog:https://blog.scuolaleonardo.com/it/2024/02/21/da-kagawa-a-piacenza-il-viaggio-di-akiko-tra-amore-italiano-e-multiculturalita-in-italia/Per informazioni sui corsi della Scuola Leonardo da Vinci:  www.scuolaleonardo.comSe vuoi contattarci o proporre qualche tema da affrontare nei prossimi episodi scrivi a podcast@scuolaleonardo.com----------- ENGLISH ------------From Kagawa to Piacenza: Akiko's Journey of Love, Learning, and Cultural Blends in ItalyThere are so many students at Scuola Leonardo da Vinci who, for one reason or another, choose to completely change their lives by moving to Italy. Today we meet Akiko, a Japanese girl who studied with us for several months between 2019 and 2021 and moved to Italy to follow her heart. She has lived in Piacenza for four years with her Italian partner.In this episode, we will listen to her story, some anecdotes about her Italian journey, and what she loves most about Italy.You can also read her interview on our blog: https://blog.scuolaleonardo.com/2024/02/21/from-kagawa-to-piacenza-akikos-journey-of-love-learning-and-cultural-blends-in-italy/For information on the Scuola Leonardo da Vinci courses:  www.scuolaleonardo.comTo contact us or to propose some topics, write to podcast@scuolaleonardo.com

In recent years there have been a handful of new Godzilla movies produced in America. But Godzilla Minus One was made in Japan, where the franchise started, and its story brings audiences back to the genesis of the monster: the aftermath of World War II. Godzilla Minus One focuses on Koichi Shikishima, a kamikaze pilot who, after opting not to fulfill his military responsibility, returns to his home in Tokyo. After learning his parents died in the bombing of Tokyo, Koichi meets Noriko, a young woman who is taking care of an orphan child named Akiko. Together they try to start a new life and leave the life of war behind them. That is, until Godzilla emerges and threatens the lives of the Japanese people. ATMI producers Isaiah Hernandez, Logan Ehrhart, and Ormund Alaois sat down to talk about this new Godzilla film, its unique focus on its human characters, how it compares to other Godzilla movies, and much more. Hosted by Jordan Kehl.  Music by Kendrick Whiteman. Many thanks to supporters of our podcast, including the Alaska State Council on the Arts. The views expressed in this program do not necessarily represent the views of our sponsors. Alaska Teen Media Institute is based in Anchorage, Alaska. We would like to acknowledge the Dena'ina people, whose land we work on.