Podcasts about Helical

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Best podcasts about Helical

Latest podcast episodes about Helical

People Property Place
#125 Sue Clayton - Senior Independent Advisor & Non Exec

People Property Place

Play Episode Listen Later May 15, 2025 64:46


Sue Clayton - Senior Independent Advisor & Non Exec How do you stay at the top of your game across four decades in commercial real estate? In this episode, I sit down with Sue Clayton, former Managing Director of Capital Markets at CBRE, board member, investor, adviser, and Co-Founder of Real Estate Balance - to break down a career built on trust, consistency, and integrity. We cover how Sue rose through the ranks in a male-dominated industry, her approach to building long-term client relationships, and how she transitioned into a successful portfolio career after leaving CBRE. Sue shares what it was like advising on billions of pounds of transactions, her board experience with companies like SEGRO, Blue Coast Capital and Helical, and why she's passionate about driving greater inclusion across the industry. If you care about leadership, longevity, and building trust this episode is for you. Key Topics Covered In This Episode: * A 40-Year Career In Commercial Real Estate – From graduate at Richard Ellis to international CBRE board member. * Building Trust in Brokerage – How she built a reputation through discretion, detail, and doing the right thing. * Building CBRE Capital Markets – What it took to lead during mergers, acquisitions, and global expansion. * Leadership Lessons – How to manage people, politics, and priorities Why saying “no” to a deal can build more credibility than chasing fees. * Transitioning to Board Roles – The skills and mindset shift needed to go from operator to advisor. * What makes an effective Non-Exec in today's market. * Supporting the Next Generation – The story behind Real Estate Balance and Pathways to Property. Oh, and one last thing… In every episode, I ask each guest: Who are the People, what Property, and which Place they would invest in if they had £500m at their disposal? Don't miss Sue's answer - especially if you're interested in long-term value and social impact. Got any thoughts or questions about this podcast? Drop them in the comments, I'd love to hear from you. And if you're enjoying the show, hit subscribe and turn on notifications so you never miss an episode. The People Property Place Podcast is powered by Rockbourne – Recruiting Leadership & Future Leadership hires for Real Estate Funds, Owners, Investors & Developers. #realestate #property #nonexec #advisory

Composites Weekly
Wichita State Research Team Advances Composites with Helical CNTs – Interview with Dr. Davood Askari

Composites Weekly

Play Episode Listen Later Apr 30, 2025 22:28


On this episode, Dr. Davood Askari joins the podcast to discuss their latest research work. Davood, an Associate Professor of Mechanical Engineering at Wichita State University, leads a research team that has created a breakthrough nanocomposite material. Engineered to significantly enhance the strength, durability, multifunctionality, and performance of lightweight structures, this innovation has broad applications across industries. […] The post Wichita State Research Team Advances Composites with Helical CNTs – Interview with Dr. Davood Askari first appeared on Composites Weekly. The post Wichita State Research Team Advances Composites with Helical CNTs – Interview with Dr. Davood Askari appeared first on Composites Weekly.

NatWest Corporates and Institutions
Property Perspectives: The retrofit experience

NatWest Corporates and Institutions

Play Episode Listen Later Apr 1, 2025 17:47


The latest trends and sustainability innovations in the world of commercial real estate.In this episode, our host Ashley Toy sits down with Laura Beaumont, Head of Sustainability at Helical PLC, a leading office developer in central London. Together, they dive into the challenges of retrofitting large commercial properties and the strategies shaping their approach – with a  particular focus on Helical's 100 New Bridge Street, London development.NB. This was recorded on 13 February 2025.Get more tips, tools, and strategies to help navigate your sustainability journey today:Unlocking value in commercial real estate: strategies to decarbonise for growthCase Study: How Robertson Group is seizing new opportunities through retrofittingCase Study: How Barwood Capital is leveraging sustainability for long-term successCarbon Planner: sign up to measure your carbon footprint and explore how your business could potentially reduce emissionsRetrofit training progress: support to help you make your premises more energy efficient

Atcha Will Drive Podcast
A Helical Groove Episode - AWWD292 - djset - techno - deep - electronic music

Atcha Will Drive Podcast

Play Episode Listen Later Jan 19, 2025 72:03


Don't forget to share the good vibes by smashing that like button! Tracklist (Time – Title – Artist – Label): 00:00:00 – Andon 2 – Troy – Dynamic Reflection 00:06:11 – Crash – BLNDR – Granulart Recordings 00:09:22 – Helical Structure – Kessell – Granulart Recordings 00:13:53 – Claim – Kxel – Naked Lunch 00:20:30 – Phobia – Floorplan – M-Plant (USA) 00:26:10 – El Recorrido – Acid Mondays – Deep Vibes 00:33:53 – La Plainte d'Aurore – Tour-Maubourg –...Lire la suite Lire la suite

BH Sales Kennel Kelp CTFO Changing The Future Outcome
Unscrewing Tyranny: Resisting Global Authoritarian Trends"

BH Sales Kennel Kelp CTFO Changing The Future Outcome

Play Episode Listen Later Oct 3, 2024 17:03


Screw big guv Grandpa Bill's Grunts & Groanshelical or advancing spiral threads  THIS IS A PLAY ON WORDS TO THIS THEME! Helical vs. Advancing Spiral Threads: A ClarificationHelical threads and advancing spiral threads are often used interchangeably, as they describe a similar type of thread pattern. However, there are subtle nuances that differentiate them.THIS IS THE THEME!!! Screw big guv.com- Resisting Global Authoritarian Trends like social media censorship mandates-etc."Turning the Screws" in a Global Context- "Turning the Screws: Global Regimes Tightening Their Grip" "Screwed In: The Rise of Authoritarianism Worldwide" "Unscrewing Tyranny: Resisting Global Authoritarian Trends" "Turning the Screws on Freedom: The Erosion of Human Rights" "Screwing Down Dissent: Crackdowns on Opposition Movements" "Unscrewing Censorship: Fighting for a Free Press" "Turning the Screws in Asia: The Growing Influence of Authoritarian Regimes" "Screwed In Europe: The Backlash Against Democracy" "Unscrewing the Middle East: Struggles for Freedom and Democracy" #globalpolitics,#authoritarianism,#humanrights,#democracy,#freedom#oppression,#censorship,#activism,#resistance,#dictatorship,#totalitarianism,#surveillance,#repression,#protests,#revolution,#civildisobedience,#socialjustice,#internationalrelations,#asia,#europe,#middleeast,#africa,#latinamerica,#china,#russia,#iran,#egypt,#arabspring,#hongkongprotests,OK Playing Chess-boring!The BH Sales Kennel Kelp Holistic Healing Hour ExperienceWebsite: https://www.7kmetals.com/grandpabillYouTube: Bill Holt@billholt8792Social Media: https://www.facebook.com/bill.sales.524Social Media:https://www.instagram.com/bradybrodyboy12/Email Message Board: https://podcasters.spotify.com/pod/show/bhsalesJOIN US EVERY TUESDAY AT 6PM. EST. Seth Leaf Pruzansky Freedom Snap-⁠https://freedomsnap.org/Seth/⁠https://www.imawakenowwhat.com/BH Sales Kennel Kelp Holistic Virtual MallPatriot Supply Link: ⁠⁠⁠https://mypatriotsupply.com/?rfsn=5615494.137cb6⁠⁠⁠Health Ranger Link:⁠⁠⁠https://www.healthrangerstore.com/?⁠⁠rfsn=301296.96452b2&utm_source=HR_Affiliate&utm_campaign=14708&utm_affiliate=301296⁠⁠⁠⁠⁠⁠⁠Healer.com⁠⁠⁠⁠: ⁠⁠⁠⁠⁠https://www.HealerCBD.com/?ref=11⁠⁠Sharon Little-https://newvibeholistichealing.myshopify.com Tam Veilleux-#HealingSpa, #HolisticHealing, #Wellness, #SelfCare, #BrunswickMaine,Tim Doyle Path to Oneness-https://thepathtooneness.com/ Byron Athene -https://byronathene.com/Isabella Thor,NLP-https://isabellathor.com/Seth Leaf Pruzansky Freedom Snap-⁠https://freedomsnap.org/Seth/⁠https://www.imawakenowwhat.com/Holistic Actions-https://www.holisticactions.comDr.Anthony Metivier -https://www.magneticmemorymethod.com/Raquel Spring-https://www.raquelspring.com/Dr. Christiane Northrup-https://open.substack.com/pub/truenorthdr/p/dr-northrups-daily-dose-of-health-987?r=och94&utm_campaign=post&utm_medium=email Creative Solutions for Holistic Healthcare

Structure Talk
Foundation Repair Options (with Michael from Standard Water)

Structure Talk

Play Episode Listen Later Sep 9, 2024 33:03 Transcription Available


In this episode, Reuben Saltzman and Tessa Murry interview Michael from Standard Water about helical piers. They discuss the process of stabilizing homes using helical piers, the different applications for helical piers, and the cost associated with the installation. They also touch on the benefits of helical piers for decks and the limitations of helical piers for foundation walls with significant bowing or horizontal cracks. In this conversation, Stephen from Standard Water explains different methods for stabilizing foundation walls. He discusses using fortress carbon fiber straps, power braces, and earth plates. He also mentions push piers as a solution for foundation settlement. The cost of these systems ranges from $1,000 to $1,450. Stephen emphasizes the importance of addressing foundation issues early and provides tips for homeowners to monitor cracks and movement. He also mentions the use of benchmarks and laser measurements for long-term monitoring.TakeawaysHelical piers are a popular method for stabilizing homes and structures.Helical piers are like giant corkscrews that are driven into the ground using hydraulic pressure.The length of the helical piers depends on the depth required to reach a load-bearing strata.Helical piers can be used to stabilize various structures, including front porches, garages, and decks.The cost of helical piers varies depending on the size and complexity of the project.Helical piers are not suitable for foundation walls with significant bowing or horizontal cracks. Fortress carbon fiber straps are recommended for stage one or stage two foundation issues, as long as lateral movement is under two inches.Power braces and earth plates are alternative options for stabilizing foundation walls when movement exceeds two inches.Push piers lift settled foundations and can be a non-invasive solution.The cost of stabilization systems ranges from $1,000 to $1,450.Homeowners should monitor cracks and movement in their foundation walls and seek professional help if they worsen.Benchmarks and laser measurements can be used for long-term monitoring of foundation stability.Chapters00:00 Introduction and Background01:39 What is a Helical Pier?06:35 Applications of Helical Piers12:23 Cost of Helical Piers13:18 Helical Piers for Decks17:12 Limitations of Helical Piers for Foundation Walls18:23 Methods for Stabilizing Foundation Walls20:48 Fortress Carbon Fiber Straps: A Solution for Stage One and Stage Two21:36 Power Braces and Earth Plates: Alternative Options for Foundation Stabilization23:50 Cost of Foundation Stabilization Systems28:02 Monitoring Foundation Cracks and Movement29:12 Long-Term Monitoring with Benchmarks and Laser Measurements

Sportsmen's Nation - Whitetail Hunting
Hunting Gear Podcast - Bowhunting Setups For 2024

Sportsmen's Nation - Whitetail Hunting

Play Episode Listen Later Sep 6, 2024 61:19


In this episode of the Hunting Gear podcast, Dan Johnson and Ricky Brule discuss their bow setups, arrow choices, and fletching preferences. They also touch on the importance of quality components and the impact of technology on the price of hunting gear. The conversation highlights the significance of customer service and how companies handle product issues. They also explore the benefits of helical fletching and the stability it provides during arrow flight. Overall, the discussion emphasizes the importance of confidence in one's gear choices and the need for personal experimentation to find the right setup. In this conversation, Dan Johnson and Ricky Brule discuss their preferences and experiences with different archery gear. They cover topics such as arrow weight, FOC (front of center), kinetic energy, broadheads, and arrow rests. They also touch on the advantages and disadvantages of single-pin sights versus multi-pin sights. Overall, the conversation provides insights into the factors that archers consider when choosing their gear and the importance of finding what works best for individual preferences and hunting situations. Takeaways: The choice of bow setup, arrow, and fletching is a personal preference that should instill confidence in the hunter. Quality components, such as inserts and broadheads, are crucial for optimal performance and accuracy. Companies that prioritize customer service and take responsibility for product issues earn customer loyalty. Helical fletching can provide stability and improve downrange accuracy, especially at longer distances. Experimentation and personal experience are key to finding the right gear setup for each individual hunter. Consider arrow weight and FOC for optimal performance and penetration Kinetic energy is important for determining arrow penetration Fixed blade broadheads may provide better penetration than mechanical broadheads Arrow rests should be simple and reliable Single-pin sights offer simplicity and focus, while multi-pin sights provide versatility Choose gear that suits your hunting style and preferences Learn more about your ad choices. Visit megaphone.fm/adchoices

Sportsmen's Nation - Big Game | Western Hunting
Hunting Gear Podcast - Bowhunting Setups For 2024

Sportsmen's Nation - Big Game | Western Hunting

Play Episode Listen Later Sep 6, 2024 54:19


In this episode of the Hunting Gear podcast, Dan Johnson and Ricky Brule discuss their bow setups, arrow choices, and fletching preferences. They also touch on the importance of quality components and the impact of technology on the price of hunting gear. The conversation highlights the significance of customer service and how companies handle product issues. They also explore the benefits of helical fletching and the stability it provides during arrow flight. Overall, the discussion emphasizes the importance of confidence in one's gear choices and the need for personal experimentation to find the right setup. In this conversation, Dan Johnson and Ricky Brule discuss their preferences and experiences with different archery gear. They cover topics such as arrow weight, FOC (front of center), kinetic energy, broadheads, and arrow rests. They also touch on the advantages and disadvantages of single-pin sights versus multi-pin sights. Overall, the conversation provides insights into the factors that archers consider when choosing their gear and the importance of finding what works best for individual preferences and hunting situations.Takeaways:The choice of bow setup, arrow, and fletching is a personal preference that should instill confidence in the hunter.Quality components, such as inserts and broadheads, are crucial for optimal performance and accuracy.Companies that prioritize customer service and take responsibility for product issues earn customer loyalty.Helical fletching can provide stability and improve downrange accuracy, especially at longer distances.Experimentation and personal experience are key to finding the right gear setup for each individual hunter. Consider arrow weight and FOC for optimal performance and penetrationKinetic energy is important for determining arrow penetrationFixed blade broadheads may provide better penetration than mechanical broadheadsArrow rests should be simple and reliableSingle-pin sights offer simplicity and focus, while multi-pin sights provide versatilityChoose gear that suits your hunting style and preferences  

Hunting Gear Podcast
Bowhunting Setups For 2024

Hunting Gear Podcast

Play Episode Listen Later Sep 6, 2024 61:19


In this episode of the Hunting Gear podcast, Dan Johnson and Ricky Brule discuss their bow setups, arrow choices, and fletching preferences. They also touch on the importance of quality components and the impact of technology on the price of hunting gear. The conversation highlights the significance of customer service and how companies handle product issues. They also explore the benefits of helical fletching and the stability it provides during arrow flight. Overall, the discussion emphasizes the importance of confidence in one's gear choices and the need for personal experimentation to find the right setup. In this conversation, Dan Johnson and Ricky Brule discuss their preferences and experiences with different archery gear. They cover topics such as arrow weight, FOC (front of center), kinetic energy, broadheads, and arrow rests. They also touch on the advantages and disadvantages of single-pin sights versus multi-pin sights. Overall, the conversation provides insights into the factors that archers consider when choosing their gear and the importance of finding what works best for individual preferences and hunting situations. Takeaways: The choice of bow setup, arrow, and fletching is a personal preference that should instill confidence in the hunter. Quality components, such as inserts and broadheads, are crucial for optimal performance and accuracy. Companies that prioritize customer service and take responsibility for product issues earn customer loyalty. Helical fletching can provide stability and improve downrange accuracy, especially at longer distances. Experimentation and personal experience are key to finding the right gear setup for each individual hunter. Consider arrow weight and FOC for optimal performance and penetration Kinetic energy is important for determining arrow penetration Fixed blade broadheads may provide better penetration than mechanical broadheads Arrow rests should be simple and reliable Single-pin sights offer simplicity and focus, while multi-pin sights provide versatility Choose gear that suits your hunting style and preferences Learn more about your ad choices. Visit megaphone.fm/adchoices

Structure Talk
Basement water problems and solutions (with Steve Grohn)

Structure Talk

Play Episode Listen Later Aug 26, 2024 49:12


In this episode, Reuben and Tessa are joined by Steve Grohn, owner of Standard Water, who shares his expertise on basement waterproofing and other related services and they discuss basement water issues and the importance of proper drainage. They also address common misconceptions and scams in the industry, emphasizing the importance of providing accurate solutions to homeowners. Steve highlights the comprehensive approach his company takes, considering factors such as gutters, downspouts, and grading before recommending drain tile installation. He also discusses the measures his company takes to minimize dust and ensure a clean work environment. In this conversation, Steve Grohn discusses various aspects of basement waterproofing and foundation repair. He explains the process of installing drain tile systems, the challenges of removing concrete during basement waterproofing, and the importance of proper waterproofing to prevent water intrusion. Steve also touches on the topic of radon mitigation and the benefits of using drain tile systems in conjunction with radon mitigation systems. Additionally, he briefly mentions the use of helical piers and push piers for foundation repair.TakeawaysProper drainage is crucial for preventing basement water issues.It is important to address the root cause of water intrusion rather than just installing drain tile as a quick fix.Some companies use fear tactics and misinformation to sell unnecessary services.Standard Water takes a comprehensive approach, considering factors such as gutters, downspouts, and grading before recommending drain tile installation.Dust control measures, such as negative air pressure and HEPA filters, are essential during basement waterproofing projects. Basement waterproofing involves the installation of drain tile systems to prevent water intrusion.Removing concrete during basement waterproofing can be a labor-intensive process.Proper waterproofing is essential to prevent water damage and mold growth in basements.Drain tile systems can be used in conjunction with radon mitigation systems to remove radon gas from basements.Helical piers and push piers are used for foundation repair to stabilize and lift sinking or settling foundations.Chapters00:00 Introduction and Water Heater Failure01:55 Sponsor Shoutout and Minnesota's Best Award03:34 Guest Introduction and Overview of Steve's Companies05:36 Differentiating Standard Water from Competitors11:44 Scams and Misinformation in the Waterproofing Industry18:25 Considering the Big Picture and Multiple Solutions22:31 Dust Control Measures During Basement Waterproofing25:00 Basement Waterproofing and Drain Tile Systems29:16 The Challenges of Concrete Removal in Basement Waterproofing38:47 The Importance of Proper Waterproofing45:14 Combining Drain Tile Systems with Radon Mitigation

MTD Audiobook
Helical Motion

MTD Audiobook

Play Episode Listen Later Jul 18, 2024 7:52


The introduction of the ISCAR HELIMILL in the 1990s marked a significant milestone in milling tools. It changed the design of milling tools with indexable inserts, establishing a new approach that would help to shape the industry. The breakthrough was achieved using a parallelogram-shaped carbide insert, featuring a helical cutting edge formed by the intersection of the insert's helical side and shaped top surfaces (Fig. 1). The HELIMILL concept offers several advantages. Firstly, the consistency of the rake and relief angles along the insert's cutting edge, when mounted on a tool reduces cutting force variations and ensures a smooth cutting action. Secondly, the uniformity of the insert's cutting wedge enhances its strength. Lastly, the helical cutting edge's proximity to the imaginary cylinder generated by a rotating tool improves accuracy compared to the straight edge found in previous-generation milling inserts. These advancements have elevated milling performance. Over the years, continuous improvement has led to significant changes in the HELIMILL inserts. The helix of the cutting edge has become more aggressive, and the top surface topology has become more intricate. Combined with advanced carbide grades, these new designs have ushered in a new level of performance. However, the parallelogram insert shape limits the number of indexable cutting edges to two. To maximise the efficiency of cemented carbides, a new round of insert development was initiated. The successful adaptation of the helical cutting edge to triangular inserts addressed this limitation. The triangular insert concept not only provides three cutting edges but also offers additional benefits. When compared to other shapes with equal cutting-edge lengths, the triangular shape provides a wider central area. This allows for an increase in the central bore size, enabling the use of a clamping screw with a larger thread. As a result, the insert securing is strengthened, contributing to the overall durability of the milling tool assembly. Additionally, the triangular shape enhances the ramping-down cutting capability. Overall, the introduction of the ISCAR HELIMILL and its subsequent advancements have revolutionised the milling tool industry. The use of helical cutting edges and triangular inserts has significantly improved performance, accuracy and durability, pushing milling capabilities to new levels. A proximate successor to the HELIMILL is the HELI-3-MILL, a family of milling tools introduced by ISCAR that features triangular indexable inserts (Fig. 2). The advantages of the ‘helical triangle' highlight why this family has gained popularity in the market. However, it is important to note that this does not mean the triangle shape will completely replace the traditional parallelogram contour with helical cutting edges soon. The parallelogram shape still possesses a competitive edge. Paradoxically, the narrow width of the parallelogram-shaped insert, which is considered a drawback when compared to the triangular shape, also offers certain advantages. Firstly, a narrower insert allows for an indexable design suitable for smaller tool diameters. Secondly, this insert geometry reduces the depth of the chip gullet, strengthening the cross-section of the tool body. This feature is particularly important for extended flute cutter designs where higher strength and rigidity of the body are crucial. The parallelogram insert structure also permits increased corner radii. Additionally, the classical shape is well-suited for high feed milling (HFM) inserts, which can be mounted in existing pockets, effectively transforming a 90-degree tool into an efficient HFM cutter. Moreover, the ‘helical parallelogram' has a smaller overall length compared to the ‘helical triangle' for the same cutting length. Therefore, it would be premature and incorrect to dismiss classical parallelogram inserts. As a result, the development of 90-degree indexable milling cutters harmoniously combines both approaches, utilising both triangular and parallelogram-shaped inserts. While the triangular insert concept dominates modern designs, the parallelogram insert principle remains relevant. The HELIMILL platform continues to be updated with new advantageous products. ISCAR's recently developed products relating to milling cutters with parallelogram-shaped inserts demonstrate that the traditional design approach remains effective and capable of meeting the demands of modern manufacturing. Milling high-temperature superalloys and titanium (ISO S group of applications), as well as difficult-to-cut austenitic and duplex stainless steel (ISO M group), presents challenges. Effective coolant supply, particularly pinpointed high-pressure cooling (HPC), can significantly reduce the heat load on the cutting edge, enhancing lubrication and chip removal. This leads to higher cutting data and enables larger radial engagements, resulting in a higher metal removal rate (MRR). Moreover, HPC facilitates the production of tighter and curled chips, allowing for tool designs with smaller chip gullets and higher tooth density. Taking these factors into consideration, ISCAR has expanded its HELI2000 family (the latest version of the HELIMILL) by introducing new tools that incorporate an HPC option within the tool body. The design of these tools has been optimised using computational fluid dynamics (CFD). They are available in both integral-body configurations and as relatively small-sized exchangeable heads with indexable inserts, which are compatible with ISCAR's modular systems MULTI-MASTER and FLEXFIT (Fig. 3). HELI2000 integrates the HELIMILL and HELIPLUS families, combining their latest developments into a single portfolio. This includes the introduction of two new highly efficient carbide grades: IC5600, designed for machining steel (ISO P group), and IC716, specifically tailored for cutting titanium. Additionally, the insert range has been expanded with new cutting geometries. This includes inserts with a high positive chipformer for milling titanium, chip-splitting cutting edges for productive roughing, and other designs. Furthermore, the range now includes inserts with reinforced cutting edges for high feed milling of hard materials up to HRc 60 hardness (ISO H group, Fig. 4). These new products are also part of ISCAR's HELIALU family, which consists of milling tools with parallelogram-shaped inserts for machining aluminium alloys (ISO N group). The expansion of this family includes indexable endmill heads with threaded adaptations for both MULTI-MASTER and FLEXFIT systems, providing the option for high-pressure cooling (HPC). The screw-in design configuration of the heads significantly enhances the customisation capabilities of HELIALU tools, allowing for a wide range of MULTI-MASTER and FLEXFIT shanks, adaptors, extensions, and reducers to be utilised. Therefore, the development of the ‘helical parallelogram' has not ceased, and the traditional HELIMILL continues to gain momentum. This development follows a gradual upward helix, revisiting past turns but at a more advanced stage.

PropCast
#197: City grandee Gerald Kaye looks back at his career as he retires as CEO from Helical

PropCast

Play Episode Listen Later Jul 11, 2024 28:56


Andrew Teacher talks to the outgoing CEO of Helical, Gerald Kaye, on a life spent in property, the challenges facing the London real estate market, and what he plans to do post-Helical.

When the Curves Line Up
2024, May 25: Capella at Helical Rising

When the Curves Line Up

Play Episode Listen Later May 22, 2024 3:54


May 25, 2024:  The bright star Capella rises before sunrise, making its first morning appearance of the year.  Mars and Saturn are in the eastern sky during twilight. See the accompanying article - 2024, May 25: Capella at Helical Rising --- Send in a voice message: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/message Support this podcast: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/support

Kanazawa University NanoLSI Podcast
Kanazawa University NanoLSI Podcast: Researchers fix the chirality of helical proteins

Kanazawa University NanoLSI Podcast

Play Episode Listen Later Feb 22, 2024 5:34


Researchers fix the chirality of helical proteinsHello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Naoki Ousaka, Mark J. MacLachlan and Shigehisa Akine at the Kanazawa University NanoLSI.The research described in this podcast was published in Nature Communications in October 2023 Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Researchers fix the chirality of helical proteinsResearchers at Kanazawa University report in Nature Communications how they can control chirality inversion in α helical peptides.The function of a protein is determined by its structure – prompting great interest in how to manipulate these structures. The structure is defined not just by the sequence of amino acids that make it, but the shape these acids make – the secondary structure – as well as how that shape is then folded. The most common secondary protein structure is the α-helix, which can coil to the right or left. This coiling direction in turn determines how it engages with other chiral structures, which may be the form of a light beam or another molecule. Although molecular components and environmental factors can favor a particular coiling direction over the other, helical molecules tend to flip between the two coil directions. Now Naoki Ousaka, Mark J. MacLachlan and Shigehisa Akine at Kanazawa University in Japan have shown how they can control and fix the coil direction.Helical proteins are chiral molecules, which means that the molecule's shape cannot be fitted into its mirror image. In nature helical proteins often have other chiral components, such as sugars or amino acids, and these will determine which way the protein coils. However, there is a lot of interest in synthesizing artificial helical proteins that have different chemical components and hence functions not found in nature, and these may not have other chiral components. Nonetheless having both types or “enantiomers” of the chiral molecule can be hazardous because of the significant differences in behavior between the two chiral forms, one of which may be benign or even therapeutic while the other is toxic. Hence, there is demand for other ways of selecting and fixing the chirality.So how did they go about this?Ousaka, MacLachlan and Akine synthesized α helical molecules solely from achiral components. They included bulky segments so that the molecule tended towards the larger rings of the α helical structure, as well as side chains of piperidine – molecular components that are common in pharmaceuticals. These side chains can be cross linked to “staple” the molecule into either the righthanded or lefthanded coil, inhibiting flipping between the two – chiral inversion. Finally they added another molecular component, known as an ester  – the L-Val-OH residue. This would switch the direction of the coil in response to acidic or basic environments due to preferences in the interaction between oxygen atoms in the ester and the amino acid backbone.The researchers used a range of chiral characterization methods including circular dichroism, nuclear magnetic resonance and liquid chromatography. They found that with the molecule stapled just once, it would slow down the flipping between enantiomers by a factor of 106, although this still occurred over minutes. Changing the solution to acid or alkali also successfully determined which enantiomer was favoured. However, stapling the molecule twice slowed down the chirality inversion by a factor of 1012, so that the molecular chirality was stable for years. This increased energy barrier to chirality inversion could then be overcome by heating the sample to very high temperatures to switch betNanoLSI Podcast website

Book 101 Review
Natural Philosophy by Helical

Book 101 Review

Play Episode Listen Later Dec 28, 2023 23:29


Available on Amazon and leading online bookstores worldwide. https://www.idevaffiliate.com/32863/idevaffiliate.php?id=1364&url=1038 --- Send in a voice message: https://podcasters.spotify.com/pod/show/daniel-lucas66/message

The OTA Podcast
OTA 2023 Annual Meeting Selected Paper: A Comparison of Helical Blade and Lag Screw Fixation in the Treatment of Intertrochanteric Hip Fractures with Cephalomedullary Nails

The OTA Podcast

Play Episode Listen Later Nov 7, 2023 11:12


Host Dr. Michael Blankstein interviews paper author Dr. Garrett Cavanaugh. This paper was presented at the 2023 OTA Annual Meeting. To see the abstract while you listen, download the free ConveyMED App: Apple Store click here Google Play click here  For additional educational resources visit https://ota.org/ Thank you to Stryker for sponsoring this episode.  For more information on the Stryker Alliance program visit https://alliancecanhelp.com.   To listen to the podcast: "Help Them Help You: Creating Orthopaedic Trauma Value Through a Hospital Alliance," download the ConveyMED app for free and listen: https://share.conveymd.com/b1ro86mQDnqBBkA28 .  To listen on Apple podcasts: https://podcasts.apple.com/us/podcast/help-them-help-you-creating-orthopaedic-trauma-value/id1505387332?i=1000621492861 , or on Spotify: https://podcasts.apple.com/us/podcast/help-them-help-you-creating-orthopaedic-trauma-value/id1505387332?i=1000621492861 

Podcast Business News Network Platinum
8936 Steve Harper Interviews Michael Barry Founder of Helical

Podcast Business News Network Platinum

Play Episode Listen Later Sep 27, 2023 26:30


Steve Harper Interviews Michael Barry Founder of Helical -- chiraltechnology.comhttps://onlineradiobox.com/search?cs=us.pbnnetwork1&q=podcast%20business%20news%20network&c=ushttps://mytuner-radio.com/search/?q=business+news+networkhttps://streema.com/radios/search/?q=podcast+business+news+network

Podcast Business News Network Platinum
8876 Steve Harper Interviews Michael Barry Founder of Helical

Podcast Business News Network Platinum

Play Episode Listen Later Sep 20, 2023 18:34


Steve Harper Interviews Michael Barry Founder of Helical -- chiraltechnology.comhttps://onlineradiobox.com/search?cs=us.pbnnetwork1&q=podcast%20business%20news%20network&c=ushttps://mytuner-radio.com/search/?q=business+news+networkhttps://streema.com/radios/search/?q=podcast+business+news+network

Podcast Business News Network Platinum
8678 Steve Harper Interviews Michael Barry Founder of Helical

Podcast Business News Network Platinum

Play Episode Listen Later Sep 1, 2023 27:14


Steve Harper Interviews Michael Barry Founder of Helical -- chiraltechnology.comhttps://onlineradiobox.com/search?cs=us.pbnnetwork1&q=podcast%20business%20news%20network&c=ushttps://mytuner-radio.com/search/?q=business+news+networkhttps://streema.com/radios/search/?q=podcast+business+news+network

Down Cellar Studio Podcast
Episode 261: 10th Annual Pigskin Party

Down Cellar Studio Podcast

Play Episode Listen Later Aug 31, 2023 49:49


  Thank you for tuning in to Episode 261 of the Down Cellar Studio Podcast. Full show notes with photos can be found on my website.    This week's segments included:   Off the Needles, Hook or Bobbins On the Needles, Hook or Bobbins Brainstorming From the Armchair Knitting in Passing KAL News On a Happy Note Quote of the Week   Thank you to this episode's sponsors:     Off the Needles, Hook or Bobbins   Sweet Liberty  Socks Yarn: Hypnotic Yarn Plush Sock in the Sweet Liberty Colorway (July 2023 Yarnable Colorway) Needles: US 1.5 (2.5 mm) Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Ravelry Project Page Check out my July 2023 Yarnable Unboxing Video Get $5 off with coupon code BOSTONJEN using my Affiliate Link 272 meters for Stash Dash   Summer Scrappy Helical Socks Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Yarn: sock yarn minis and scraps Ravelry Project Page (started in May, finished in August) In this project, I used Helical knitting using Video Tutorial from Knitty Natty & Cate's Clasp Weft join- check out my YouTube Tutorial  by clicking here. 272 meters for Stash Dash   Liz's Water Bottle Holder Yarn: Loops & Threads Capri Eco Cotton (85% Cotton, 15% Polyester) Hook: F (3.75 mm) Pattern: None Ravelry Project Page From Amazon, I ordered Black Buckles to allow for adjusting the length of the strap. My friend Liz was walking around sightseeing on a recent trip to St. Louis and mentioned she may need a water bottle holder like the one I made for Hattie (Ravelry Project Page). 169.2 meters for Stash Dash   Mini Skein Hexagon Blanket Pattern: Basic Crochet Hexagon Pattern & Tips from Make Do and Crew Website & YouTube Tutorial Hook: F (3.75 mm) Yarn: Mini skeins from 2022 agirlandherwool Advent Calendar, 24 Days of Cheer Swap minis + other scraps/swap yarn Ravelry Project Page I've been closing the end of each hexagon with this join- link to Instagram post 4 rounds per hexagon. 3.75 inches each. Learned double magic circle from this YouTube video. The trick is to know how to pull both loops to tighten the loop. Final blanket- 15x22 hexagons with 5 rounds of single crochet for the border. 62x80 inches (twin size- 60x80 inches) Finished blanket- 11,392 meters   Stash Dash total on the morning of 8/31/23= 21,064 meters (before counting my last spinning project).   On the Needles, Hook or Bobbins   Wild Air Farm Spinning I am spinning a 4 oz braid of Polwarth/Silk (85/15) from Jakira Farms to ply with Wild Air Farm Shetland & Pygora- Melody & Cadence (dyed in blues and greens) Twist direction: singles = Z plied = S This means when I'm spinning, my wheel is spinning clockwise and when plying my wheel is moving counter-clockwise. Ravelry Project Page Progress: morning of 8/31- spinning is complete. Plying will be done this afternoon, but I can't measure the finished yarn until it is washed and dried.   My Little Unicorn Socks Yarn: Andre Sue Knits Sock Blank in the My Little Unicorn colorway Needles: US 1.5 (2.5 mm) Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Ravelry Project Page Gray background with white and pink unicorns that look like My Little Pony. My inner 80's child loved this one. Progress: Past the heel of the second sock   Petrichor Socks Yarn: Oink Pigments Targhee Sock in the Petrichor Colorway (90% Targhee, 10% Nylon) Needles: US 1.5 (2.5 mm) Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Ravelry Project Page Progress: Past the heel of the second sock   Brainstorming   Mom's Rhinebeck Sweater. Yarn from Sweitzer's Fiber Mill from Maryland Sheep & Wool 2023. My gauge swatch in progress. I started with US 8s, then did a purl bump row and switched to US 9s. Please send your suggestions of relatively simple cardigan pattern for worsted/aran weight yarn. Socks with Pigskin Sponsor Yarn   From the Armchair   True Love Experiment by Christina Lauren. Bookshop Affiliate Link. Amazon Affiliate Link. And Then She Kissed Me by Harper Bliss. Bookshop Affiliate Link. Amazon Affiliate Link. Tom Lake by Ann Patchett. Bookshop Affiliate Link. Amazon Affiliate Link.   Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases.   Knitting in Passing   Liz, Riley and I went to the Marshfield Fair. We spent a good bit of time inside the exhibition building looking at flower arrangements, plants and other crafty items that were given awards. Lots of knitting and crochet projects as well as quilts. While the plants and things were really accessible on tables, it was nice to see that the fiber crafts were behind a low railing so you couldn't touch anything.   KAL News   Pigskin Party '23 #DCSPigskinParty23 Official Rules Find everything you need on my website or in the Start Here Thread in the Ravelry Group Register using this Google Form (you must be Registered to be eligible for prizes) Enter your projects using the Point Tally Form Find the full list of Sponsors in this Google Doc. Coupon Codes are listed in this Google Doc & in this Ravelry Thread Exclusive Items from our Pro Shop Sponsors are listed in this Ravelry Thread Questions-  ask them in this Ravelry Thread or email Jen at downcellarstudio @ gmail.com Teams will be announced on 9/1. Stay tuned to the Ravelry group and look for the "find your teams" thread. Tailgate Talk Challenge (September 7-21. Enter for points by September 30). Check out the details in this Google Doc or in this Ravelry Thread. Virtual Kick Off Weekend Thursday night for Patrons only. Patrons of every level will be invited to join. For the rest of the seaon, only those at the $5/month level and up are invited to our monthly hangouts. Friday September 8 &  Saturday September 9th, events will be open to ALL. Check out the full schedule here. Crowd Sourcing: Do you have ideas for challenges or events for this season? Share your ideas in this Ravelry Thread. Does anyone want to be a correspondent and report in before each episode with some key stats or highlights from the games, interesting post or projects?  Email me or DM me on Instagram if you're interested.   On a Happy Note Beach walk and dinner w/ Megg & Kris. Breakfast with Mom & two of her Infusion nurses we've known for years. Marshfield Fair with Liz and Riley. We watched part of the demolition derby, played some games and listened to music. Dan and I went Kayaking with Megg, Oisin, Hattie and Will, then got food from the Hingham Lobster Pound and chilled at the Rowan's. We celebrated my grandmother's 89th birthday with a fun brunch at The Friendly Toast I went to see Oppenheimer at the movies with Liz.  Then to see Barbie (for the second time) with Liz and our Mom's who hadn't seen it yet. We met early for a drink, all wearing our pink. They loved the movie. Dinner the night before Eme left for school then Megg and I brought them out to Simon's Rock for their 3rd year. It was a long day- 6 hours of driving + unpacking, organizing, a late lunch and snacks in the car singing all the way home. Riley found "Make Dolly Proud" tees while shopping w/ a friend and I sent her money to get them for us. She's making WWDD bracelets for us too! 5 of the nieces and nephews started school + Gabriella started pre-school so far. FaceTimed with Riley and Gabriella & Zach    Quote of the Week   "Most people fail in life not because they aim too high and miss, but because they aim too low and hit." ― Les Brown   ------   Thank you for tuning in!   Contact Information: Check out the Down Cellar Studio Patreon! Ravelry: BostonJen & Down Cellar Studio Podcast Ravelry Group Instagram: BostonJen1 YouTube: Down Cellar Studio Facebook: https://www.facebook.com/downcellarstudio Sign up for my email newsletter to get the latest on everything happening in the Down Cellar Studio Check out my Down Cellar Studio YouTube Channel Knit Picks Affiliate Link Bookshop Affiliate Link Yarnable Subscription Box Affiliate Link Music -"Soft Orange Glow" by Josh Woodward. Free download: http://joshwoodward.com/ Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases.    

UBC News World
Concrete Foundation Repair & Synchronized Helical Pier Lifting Services In Tulsa

UBC News World

Play Episode Listen Later Aug 17, 2023 2:36


Helical pier lifting is an industry-tested solution to major foundation problems. Call Powerlift Foundation Repair on 1-800-562-5438 for an estimate. Visit https://www.powerliftfoundationrepair.com/locations/oklahoma/tulsa/ today! Powerlift Foundation Repair City: Broken Arrow Address: 3217 S 211th E Ave #5142 Website https://www.powerliftfoundationrepair.com/ Phone +1-918-587-5438 Email astormin05@gmail.com

RackAddicts After Hours
185: Episode: 185 Helical 16-voice polyphonic Autoregressive Algorithmic Synthesizer

RackAddicts After Hours

Play Episode Listen Later Aug 5, 2023 30:30


PaperPlayer biorxiv cell biology
Helical motors and formins synergize to compact chiral filopodial bundles: a theoretical perspective.

PaperPlayer biorxiv cell biology

Play Episode Listen Later Jul 24, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.24.550422v1?rss=1 Authors: Maxian, O., Mogilner, A. Abstract: Chiral actin bundles have been shown to play an important role in cell dynamics, but our understanding of the molecular mechanisms which combine to generate chirality remains incomplete. We numerically simulate a crosslinked filopodial bundle under the actions of helical myosin motors and/or formins and examine the collective buckling and twisting of the actin bundle. We find that the myosin spinning action effectively braids the bundle, compacting it, generating buckling, and enhancing crosslinking. Stochastic fluctuations of actin polymerization rates also contribute to filament buckling and bending of the bundle. Faster turnover of transient crosslinks attenuates the buckling and enhances coiling and compaction of the bundle. Formin twisting action by itself is not effective in inducing filopodial coiling and compaction, but co-rotating formins synergize with helical motors to coil and compact the actin bundle. We discuss implications of our findings for mechanisms of cytoskeletal chirality. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

PaperPlayer biorxiv neuroscience
SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jul 18, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.18.549510v1?rss=1 Authors: Fletcher-Jones, A., Spackman, E., Craig, T. J., Nakamura, Y., Wilkinson, K. A., Henley, J. M. Abstract: Endocannabinoid signalling mediated by cannabinoid type 1 receptors (CB1Rs) is critical for homeostatic neuromodulation of both excitatory and inhibitory synapses. This requires highly polarised axonal surface expression of CB1R, but how this is achieved remains unclear. We previously reported that the H9 domain in the intracellular C-terminus of CB1R contributes to polarised surface expression by an unknown mechanism. Here we show the H9 domain binds to the endocytic adaptor protein SGIP1 to promote CB1R expression in the axonal membrane. Overexpression of SGIP1 increases CB1R axonal surface localisation but has no effect on CB1R lacking the H9 domain (CB1R{Delta}H9). Conversely, SGIP1 knockdown reduces axonal surface expression of CB1R but does not affect CB1R{Delta}H9. Furthermore, SGIP1 knockdown diminishes CB1R-mediated inhibition of presynaptic Ca2+ influx in response to neuronal activity. Together, these data advance mechanistic understanding of endocannabinoid signalling by demonstrating that SGIP1 interaction with H9 underpins axonal CB1R surface expression to regulate presynaptic responsiveness. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Multiverse 5D
DjSadhu: The helical model - our solar system is a vortex

Multiverse 5D

Play Episode Listen Later Jul 11, 2023 3:20


DjSadhu: The helical model - our solar system is a vortex

When the Curves Line Up
2023: Helical Rising of Sirius

When the Curves Line Up

Play Episode Listen Later Jul 2, 2023 8:27


2023:  The night's brightest star makes its first appearance, heliacal rising, before sunrise in the east-southeast.  The dates of first appearance depend on latitude and local weather. See the accompanying article 2023: Helical Rising of Sirius --- Send in a voice message: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/message Support this podcast: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/support

Down Cellar Studio Podcast
Episode 257: Fiber in Phoenix

Down Cellar Studio Podcast

Play Episode Listen Later Jun 30, 2023 42:48


Thank you for tuning in to Episode 257 of the Down Cellar Studio Podcast. This week's segments included: Off the Needles, Hook or Bobbins On the Needles, Hook or Bobbins From the Armchair Some Years Later In my Travels KAL News Events Life in Focus On a Happy Note Quote of the Week Thank you to this episode's sponsors: Sunsoaked Yarns, Bella Fio, Woolen Women Thanks to Mom for joining me for part of this episode! Off the Needles, Hook or Bobbins Cushion Bags Pattern: none Yarn: Lion Brand Re-Up & Other Dish Cloth Cotton Hook: F (3.75 mm) I made 2 cushion covers for Mom because the bags for her inflatable seat cushions were too small to easily fit back into. Ravelry Project Page- Cushion 1: green and aqua Ravelry Project Page- Cushion 2 : black and aqua 155 meters for Stash Dash (in the 2 projects) 2021 Scrappy Socks Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Yarn: sock yarn minis and scraps Ravelry Project Page (started in April 2021. Picked back up in September 2022) In this project, I used Helical knitting using Video Tutorial from Knitty Natty & Cate's Clasp Weft join- check out my YouTube Tutorial  by clicking here. 228 meters for Stash Dash In a Fog Mittens Pattern: In a Fog by Allison O'Mahony ($5.50 US knitting pattern available on Ravelry & the designer's website) Needles: US 4 (3.5mm) & US 6 (4.0mm) Yarn: MC: Spun Right Round (multi color) CC: Fibre Seed Costa Laurel worsted yarn in Colorway CL014 (gray) Size: Medium (3 sizes available) Ravelry Project Page 161 meters for Stash Dash Curiouser & Curiouser Socks Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Yarn:  Legacy Fiber Artz Steel Toes in the Curiouser & Curiouser Colorway Needles: US 1.5 (2.5 mm) Ravelry Project Page These count for the #legacyfiberartzknityourstashMal Will weigh these socks when I get home from Phoenix On the Needles, Hook or Bobbins Summer Rainbow Socks Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Yarn:  Desert Vista Dyeworks Viso base in the Summer Rainbow Colorway Needles: US 1.5 (2.5 mm) Ravelry Project Page Progress: Almost to the heel of sock #2 Zebra Stripes Socks Pattern: OMG Heel Socks by Megan Williams ($5 knitting pattern available on Ravelry ) Yarn: Patons Kroy in the Zebra Stripes Colorway Needles: US 1.5 (2.5 mm) Ravelry Project Page About the colorway: Progress: Finished most of the first sock Chevron Scrap Blanket Pattern: Chevron Scrap Blanket by Maria's Blue Crayon (free crochet pattern) available on Ravelry & the Maria's Blue Crayon Website. This pattern presumes you already know the c2c crochet technique. Yarn: Knit Picks Brava Worsted in White & Tranquil (light green), Lion Brand Pound of Love in Pastel Pink and Loops & Threads Snuggly Wuggly Big! in colorway Soft Lilac Hook: J (6.0 mm) Ravelry Project Page (I crocheted one of these in summer 2020- click here for that Ravelry Project Page) For help learning the Corner to Corner Crochet method you could check out this free Ravelry Download from Lauri Bolland or this video tutorial from Lion Brand on YouTube. Each section is 11 squares tall. Green, white, pink, white, purple, white. Progress: 5 strips finished. 1 more started. Once finished, I need to seam them together & debating a border. From the Armchair Demon Copperhead by Barbara Kingsolver. Bookshop Affiliate Link. Amazon Affiliate Link. The Writing Retreat by Julia Bartz. Bookshop Affiliate Link. Amazon Affiliate Link Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases. Some Years Later Cozy Classic Raglan Pattern: Cozy Classic Raglan by Jessie Maed Designs Needles: US 3 for Ribbing. US 7 for body Yarn: Rowan Cashsoft DK in color 547 Sunny Knitting Size Medium.  Finished in May 2020 I never loved the way it fits me. Riley recently wore it during sleepover, so I let her take it home. She sent me a fit check wearing it with white jean cut offs, a slick hairdo and some poppin lips! Looking gorgeous. Makes me even happier than the meters that helped me kick Jasmin's butt in 2020! In My Travels Mom and I are recording from Phoenix, Arizona at the List Perfectly Camp Listing Party Event. Mom & I gave a presentation on the Fearless Living Fund where we've already raised over $1600!  You can donate to the Fearless Living Fund to benefit the Blind Center of Nevada on Venmo. KAL News Splash Pad Party 23: May 26-July 31, 2023 Sign up using this Google Form. To confirm you're signed up, check the Stats/Registration Spreadsheet here. Click here for the full list of Sponsors with all the links you need to their websites & social media. Many of our Sponsors are offering coupon codes. Find them here- Google Doc or Ravelry Thread. Events Stash Dash, hosted by Leslie & Laura of the Knit Girllls Video Podcast starts May 26th and runs through August 31, 2023. Check out details in the knit girllls discord My total as of this episode: 1,619 meters (plus socks I haven't been able to weigh) You can check out my Stash Dash 2023 Progress on this Google Sheet. Legacy Fiber Artz Knit Your Stash MAL- check out the details on the Treehouse Fiber Arts website Runs May 29- September 4, 2023 #legacyfiberartzknityourstashMal and #flashyourstash Crafty Bingo- Craft Cook Read Repeat Podcast May 26-September 4, 2023 Grab the Bingo card over on their Instagram feed The Grocery Girls are hosting Hot Granny Square Summer MAL. Check out details in their Ravelry Group & in Episode 183 on their YouTube Channel. Summer Sock Camp hosted in the Crazy Sock Lady Ravelry Group 5/26- 8/31/2023 Maine Fiber Frolic: June 3-4th at the Windsor Fairgrounds Vermont Sheep & Wool: Sept 30 & Oct 1 at the Tunbridge Fairgrounds Check out some West Coast (US) Events on the Seattle Knitters Guild site (thanks Kristen- kips206) Life in Focus It's been a tough couple weeks with Mom having a bad reaction to her normal infusion, then Dan's mother, Marilyn passed away on June 25th. On a Happy Note Our nephew Oisin turned 15 and we enjoyed his taco truck birthday party. That same weekend, we had 3 kiddos in a dance recital, and our niece Aila was in Beauty & the Beast as Maurice that night. Mom, Riley, Millie and I grabbed dinner (and for the adults a cold beer) in between! We enjoyed Father's Day with my dad and gave him custom corn hole boards and bags! Mom, Riley and I got VIP tickets to Kane Brown at Fenway Park. We wore matching tees Mom bought for us. Not one but 2 bucks in our driveway at the same time. Stayed long enough for me to bring Dan back. Fireflies are out! I got to show our friend Liz when she came for dinner. I got to go into the ORs for the first time, after working at MGH for nearly 21 years. Quote of the Week One's life begins on so many occasions, constructing itself out of accident derived from coincidence compounded by character.–DONALD HALL —— Thank you for tuning in! Contact Information: Check out the Down Cellar Studio Patreon! Ravelry: BostonJen & Down Cellar Studio Podcast Ravelry Group Instagram: BostonJen1 YouTube: Down Cellar Studio Facebook: https://www.facebook.com/downcellarstudio Sign up for my email newsletter to get the latest on everything happening in the Down Cellar Studio Check out my Down Cellar Studio YouTube Channel Knit Picks Affiliate Link Bookshop Affiliate Link Yarnable Subscription Box Affiliate Link Music -“Soft Orange Glow” by Josh Woodward. Free download: http://joshwoodward.com/ Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases.

When the Curves Line Up
2023, May 12: Morning Moon, Saturn, Evening Helical Settings

When the Curves Line Up

Play Episode Listen Later Apr 18, 2023 4:26


May 12, 2023: The moon is near Saturn in the southeast before sunrise.  Sirius and Aldebaran are at their heliacal settings, their final appearances in the western sky after nightfall. This episode is also available as a blog post: 2023, May 12: Morning Moon, Saturn, Evening Helical Settings --- Send in a voice message: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/message Support this podcast: https://podcasters.spotify.com/pod/show/jeffrey-l-hunt/support

The Blockchain Socialist
Overthrowing The Network State: Untangling Balaji's Helical Theory of History

The Blockchain Socialist

Play Episode Listen Later Feb 26, 2023 66:46


For this episode, I'm joined by Kelsie Nabben from Blockchaingov to speak to Quinn DuPont (@quinndupont), a historian of technology who recently gave a talk about his criticisms of TNS at the Commons Stack Unconference. He also recently published an article titled A Progressive Web3: From Social Coproduction to Digital Polycentric Governance. During the episode we interrogate Balaji's misunderstandings of history and proposing the commons as an alternative framework for what is already happening in some parts of web3.Overthrowing the Network State (OTNS) is a series in collaboration with Blockchaingov where we critique The Network State  by Balaji Srinivasan while also pulling out the salvageable parts and concepts in discussion with a variety of guests. We are overall critical of Balaji's specific ideas in the book, but we want to discuss it with intellectual honesty and highlight the larger concepts around how these technologies are and could subvert state structures. You can find the first episode of OTNS where we give our initial criticisms and  alternatives here.Blockchaingov is a 5-year long, transdisciplinary research effort aimed at restoring trust in institutions at the community and global levels, by promoting better on chain and off chain distributed governance practices. Throughout the series, each discussion will include me and a member of Blockchaingov with either a new guest each episode or just a discussion between us to tackle various topics from the book.If you liked the podcast be sure to give it a review on your preferred podcast platform. If you find content like this important consider donating to my Patreon starting at just $3 per month. It takes quite a lot of my time and resources so any amount helps. Follow me on Twitter (@TBSocialist) or Mastodon (@theblockchainsocialist@social.coop) and join the r/CryptoLeftists subreddit and Discord to join the discussion.Support the show

3D Hangouts
3D Hangouts – Feather TFT, Floppy PyPortal and Helical Heart

3D Hangouts

Play Episode Listen Later Feb 15, 2023 64:47


This week @adafruit we're making a stand for the Feather ESP32-S2 Reverse TFT. Prototyping a snap fit case for the PyPortal in the shape of a floppy disk. Timelapse this week features a helical heart designed by DaveMakesStuff. YouTube Video - https://youtu.be/GLrySwYEgkA Learn Guide https://learn.adafruit.com/stand-for-feather-esp32-with-reverse-tft/ Feather ESP32-S2 Reverse TFT https://www.adafruit.com/product/5345 USB A Cable with Magnetic Tips https://www.adafruit.com/product/5652 M2.5 Hardware Kit https://www.adafruit.com/product/3299 Magnetic USB Tips Holder https://www.printables.com/model/387044-magnetic-usb-tips-holder 3D Parts Library on GitHub - https://github.com/adafruit/Adafruit_CAD_Parts Timelapse Tuesday Helical Heart By DaveMakesStuff https://social.thangs.com/m/690383 https://youtu.be/g9IfsVS6H8Y Community Makes: This Week Coming Up https://www.printables.com/model/7269-kingdom-key-yet-another-keyblade/comments/661386 https://www.printables.com/model/37200-perma-proto-feather-case/comments/661465 https://www.printables.com/model/7243-iot-gmailbox/comments/661580 https://twitter.com/shanselman/status/1625366634616737792 darksaber https://www.printables.com/model/153698-led-emeralds/comments/655982 https://www.printables.com/model/7268-prop-maker-keyblade/comments https://www.printables.com/model/208428-airpods-max-headbands-and-ears-covers/comments/630655 https://www.printables.com/model/83538-tva-time-stick-from-loki/comments/629720 https://www.printables.com/model/7281-neotrellis-sound-board/comments/628685 https://www.thingiverse.com/make:1084485 TVA Baton https://www.printables.com/model/348322-odette-the-owl/comments/627941 https://www.printables.com/model/7271-heat-set-insert-press/comments/622723 https://www.printables.com/model/7271-heat-set-insert-press/comments/643578 https://www.printables.com/model/32382-mini-usb-fume-extractor/comments/641603 https://www.printables.com/model/7163-dodecahedron/comments/639570 https://www.printables.com/model/7262-pyportal-case/comments/638626 https://www.printables.com/model/7172-pokemon-potion-usb-battery/comments/636354 https://www.printables.com/model/113360-elf-earbud-holders/comments/631012

Adafruit Industries
Helical Heart timelapse 3dprinting

Adafruit Industries

Play Episode Listen Later Feb 14, 2023 0:52


Every week we'll 3D print designs from the community and showcase slicer settings, use cases and of course, Time-lapses! This Week: Helical Heart By DaveMakesStuff https://social.thangs.com/m/690383 CR10S Pro V2 Pink Blue PLA 4hr 26mins X:242 Y:180 Z:65mm .1mm layer / .4mm nozzle 6% Infill / 1mm retract 190C / 60C 40g 60mm/s ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Adafruit on Instagram: https://www.instagram.com/adafruit Shop for parts to build your own DIY projects http://adafru.it/3dprinting 3D Printing Projects Playlist: https://www.youtube.com/playlist?list=PLjF7R1fz_OOWD2dJNRIN46uhMCWvNOlbG 3D Hangout Show Playlist: https://www.youtube.com/playlist?list=PLjF7R1fz_OOVgpmWevin2slopw_A3-A8Y Layer by Layer CAD Tutorials Playlist: https://www.youtube.com/playlist?list=PLjF7R1fz_OOVsMp6nKnpjsXSQ45nxfORb Timelapse Tuesday Playlist: https://www.youtube.com/playlist?list=PLjF7R1fz_OOVagy3CktXsAAs4b153xpp_ Connect with Noe and Pedro on Social Media: Noe's Twitter / Instagram: @ecken Pedro's Twitter / Instagram: @videopixil ----------------------------------------- Visit the Adafruit shop online - http://www.adafruit.com/?utm_source=youtube&utm_medium=videodescrip&utm_campaign=3dprinting Subscribe to Adafruit on YouTube: http://adafru.it/subscribe Adafruit Monthly Deals & FREE Specials https://www.adafruit.com/free?utm_source=youtube&utm_medium=videodescrip&utm_campaign=3dprinting Join our weekly Show & Tell on G+ Hangouts On Air: http://adafru.it/showtell Watch our latest project videos: http://adafru.it/latest?utm_source=youtube&utm_medium=videodescrip&utm_campaign=3dprinting 3DThursday Posts: https://blog.adafruit.com/category/3d-printing?utm_source=youtube&utm_medium=videodescrip&utm_campaign=3dprinting New tutorials on the Adafruit Learning System: http://learn.adafruit.com/?utm_source=youtube&utm_medium=videodescrip&utm_campaign=3dprinting Music by Bartlebeats https://soundcloud.com/adafruit -----------------------------------------

time 3d diy 3d printing timelapse infill adafruit helical g hangouts on air adafruit learning system bartlebeats layer cad tutorials playlist
PaperPlayer biorxiv neuroscience
Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Jan 9, 2023


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.09.523314v1?rss=1 Authors: Hoq, M. R., Bharath, S., Hallinan, G., Fernandez, A., Vago, F., Ozcan, K., Li, D., Garringer, H., Vidal, R., Ghetti, B., Jiang, W. Abstract: Background: The Microtubule-Associated Protein Tau (MAPT) is one of the proteins that are central to neurodegenerative diseases. The nature of intracellular tau aggregates is determined by the cell types whether neuronal or glial, the participating tau isoforms, and the structure of the amyloid filament. The transmembrane protein 106B (TMEM106B) has recently emerged as another significant player in neurodegeneration and aging. In the central nervous system, the composition of the gray and white matter differs considerably. The gray matter consists of nerve cell bodies, dendrites, unmyelinated axons, synaptic terminals, astrocytes, oligodendrocytes (satellite cells) and microglia. The white matter differs from the gray for the presence of axonal tracts as the only neuronal component and for the absence of nerve cell bodies, dendrites and synaptic terminals. Cryogenic electron microscopy (cryo-EM) studies have unveiled the structure of tau and TMEM106B, from the cerebral cortex, in several neurodegenerative diseases; however, whether tau and TMEM106B filaments from the gray and white matter share a common fold requires additional investigation. Methods: We isolated tau and TMEM106B from the cerebral cortex and white matter of the frontal lobes of two individuals affected by multiple system tauopathy with presenile dementia (MSTD), a disease caused by the MAPT intron 10 mutation +3. We used immunostaining, biochemical, genetics and cryo-EM methods to characterize tau and TMEM106B. Results: We determined that tau filaments in the gray and the white matter of MSTD individuals can induce tau aggregation and have identical AGD type 2 folds. TMEM106B amyloid filaments were also found in the gray and white matter of MSTD; the filament folds were identical in the two anatomical regions. Conclusions: Our findings show for the first time that in MSTD two types of amyloid filaments extracted from the gray matter have identical folds to those extracted from the white matter. Whether in this genetic disorder there is a relationship in the pathogenesis of the tau and TMEM106B filaments, remains to be determined. Furthermore, additional studies are needed for other proteins and other neurodegenerative diseases to establish whether filaments extracted from the gray and white matter would have identical folds. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Down Cellar Studio Podcast
Episode 242: Travels, Trials, Tales & Treats

Down Cellar Studio Podcast

Play Episode Listen Later Oct 31, 2022 65:31


Thank you for tuning in to Episode 242 of the Down Cellar Studio Podcast. For Full Show Notes with Photos, check out my website.   This week's segments included:   Off the Needles, Hook or Bobbins On the Needles, Hook or Bobbins Brainstorming From the Armchair Knitting in Passing In my Travels KAL News Life in Focus On a Happy Note Quote of the Week Thank you to this episode's sponsors: Star Knits, Adore Knit, Lolo Did It  Off the Needles, Hook or Bobbins Woolens & Nosh Sprout Socks   Yarn:  Woolens and Nosh 90% SW Targhee, 10% Nylon 3 Ply Yarn (411 yards / 100 grams) in the Sprout Colorway Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Sprout- 10 stripe- Light yellow, peach, ballet pink, maroon, dusty blue, kelly green, tapue, lighter grass green, cream, pale green. Yarn from Woolens & Nosh-  Pigskin Party Pro Shop Sponsor Project Bag- Pigskin '22 Exclusive from Anne Beady Designs  Repaired the cuff on Mom's Deja Blue Knit Picks Felici Socks from 2019.   Click here for my Ravelry Project Page.  I knit cuff down, so it was a bit of project to cut off the top of the sock, unravel back to the stockinette. Worked back up and used Jeny's surprisingly stretchy bind off to finish them.  Check out this page on Knitty for the details on this Bind Off. On the Needles, Hook or Bobbins Musselburgh Pattern: Musselburgh by Ysolda Teague (6 GBP pattern available on Ravelry & Ysolda's website) Needles: US 2 (2.75 mm) Yarn: Malabrigo Sock in Colorway 195 Black  Cast on using crochet magic circle to create number of CO sts called for in the pattern. Chose that because you can pull it tight. I then picked up and knit into those stitches. Colin & Nora's Christmas Stockings Pattern: Christmas Stockings to Knit and Crochet from Family Circle Magazine. Available in this web archive link. I've also saved it to my podcast Gmail Google Drive in case it disappears!  web.archive.org-Christmas Stockings to Knit and Crochet from Our Archives.pdf Yarn: Red Heart Super Saver in Cherry Red, Hunter Green and White Hook: G (4.00 mm) Both stockings are joined & I'm working on the cuffs.  Mermazing Socks Yarn: Hypnotic Yarn Plush Sock in the Mermazing Colorway (April 2022 Subscription Box) & mini skeins from Legacy Fiber Artz. Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Check out my  Blues and greens and purples.  Contrasting heel with LFA mini from my 2021 Advent Calendar Yarn from Pigskin Party Sponsors Hypnotic Yarn/Yarnable Box & Legacy Fiber Artz- both Snack Shack Sponsors Project Bag from Anne Beady Designs (Pro Shop Sponsor) Progress- 1st sock finished. 2nd cuff finished. Portal Socks Yarn: Legacy Fiber Artz Steel Toes Base in the Portal Colorway Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Yarn from Legacy Fiber Artz- Pigskin Party Snack Shack Sponsor Yarn- speckles. Mostly reads pink/maroons. so many tiny specks of color. taupe, green, blue, purple, gray/brown.  Progress- 1st sock finished. 2nd sock has several inches done on the leg 2021 Scrappy Socks Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Yarn: sock yarn minis and scraps Ravelry Project Page (started in April 2021. Picked back up in September 2022) In this project, I used Helical knitting using Video Tutorial from Knitty Natty & Cate's Clasp Weft join- check out my YouTube Tutorial  by clicking here. Progress- 1st sock finished. 2nd cuff finished + an inch or so of the leg. Helical knitting made these so much more interesting to me. Game changer. First Point of Libra Cowl Pattern: First Point of Libra Cowl by Laura Aylor  Needles: US 3 (3.25 mm) Yarn: Barnyard Knits, Fuse Fiber Studio, One Twisted Tree (shop formerly own Prairie Girl Danie) + other leftover sock yarn  Ravelry Project Page Yarn purchased at Vogue Knitting Live January 2020 with Lauren. Planned to make a 2 color shawl. Cast on My Cryptonite by Melanie Berg and never got more than a couple inches in. Here's the Ravelry Project Page for the shawl that's now frogged.  Inspiration color= Barnyard Knits- Pricky Pear (multi- has grays, greens and pinks). Matches new long, green, quilted coat from J. Jill.  Plus Fuse Merino Sock in Mercury Glass (gray) & Fuse in Radical Acceptance (pink) I think this project would be great for small scraps because even though each section calls for X number of rows, you could easily modify it and have wider or thinner stripes in each direction.  Spinning 4oz of 100% Natural Cotswold purchased from Long Island Livestock Company at Rhinebeck for $20. Beautiful tan color.  No real plan or prep. Just enjoying the process. Brainstorming I'd like to make a fingering weight hat using yarns from the First Point of Libra Cowl to bring to the UK in November.  Found yarn for Megg's next Nanaimo Cardigan for Christmas- Lion Brand Wool Ease Thick & Quick in the Abalone Colorway. Ordered from Joann.com From the Armchair On a Quiet Street by Seraphina Nova Glass. Bookshop Affiliate Link. Amazon Affiliate Link.Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases. Knitting in Passing I shared stories about a women who took my knitting from me on the train and started knitting it herself, about how Hattie thought my Mom's cowl was the funniest beard she ever saw, how I was recognized by a local knitting in the lobby of a theater during intermission and about a chat with lovely woman at my local nail salon. In My Travels Rhinebeck 2022: Mom, Ryan, Nicki & I had a whirlwind weekend at CAKEPalooza and Rhinebeck- the NY Sheep & Wool Festival. Come along and enjoy the sights and sounds of the trip in this video on the  https://youtu.be/JmmjF1VcIGU In this episode I shared just a few highlights. Some key links: Shameka‘s cupcakes that we bought at CAKEpalooza Rhinebeck sweaters- Mom and I each wore our Wave of Change Jackets. Click here for the Ravelry Project Page for Jen's Sweater & the Ravelry Page for Mom's sweater. On Sunday, I wore my Boxing Day Bonus Shawl. Mom wore her new Shift Cowl- click here for the Ravelry Project Page.  Mom got to share her Scrapbox Challenge project with Crispina who hosted this challenge in March 2020 Ross Farm Fiber Tour 2022 Shirts In November I'm going to the UK. I'll be visiting Manchester, Newbury & London, England & Cardiff, Wales. Do you have any tips or suggestions for me? Restaurants, shops, best ways to get theater tickets etc.  KAL News Pigskin Party'22: The Official Hashtag is #DCSPigskinParty22   Pigskin Landing Page on the Down Cellar Studio Website. Start Here Thread in the Ravelry Group Link to the Official Rules Player Registration- Google Form Check out our amazing Sponsors! Click here for the Google doc with their websites and Instagram profiles.  Check out the list of available Coupons from our amazing sponsors- Ravelry Link. Google Doc. Check out the Pigskin Exclusive Items in this Ravelry Thread Important Updates in this Episode First of the Pigskin Participation Prizes. The 10 Grand Prizes will be shared soon! Check out November's Woolen Cafe Interception Challenge hosted by Woolen Women Fibers. You can find the details in the Ravelry Group or in this  November- Woolen Cafe Interception: Woolen Women Fibers The October Interception Winner will be shared in early November in the Ravelry Group & in the next episode. Thanks again to Sunsoaked Yarns for hosting! Rule update: you need to have a Unique URL for each submission. Check out this Ravelry Post for details. I've also updated the Official Rules.  This year we'll have 10 grand prizes! Will share details in the group soon! Life in Focus Quick health update on Mom who was diagnosed with Stage 4 Lung Cancer on December 1, 2021. Her October scans showed new tumors in the pleura (lining) of her lungs which aren't responding to her Tagrisso gene therapy medicine. They'll be doing a biopsy to see if they can tell why it is resistant and perhaps there is another drug they can try. Since that will take about a month before we have results, she'll be starting chemotherapy in the meantime. 1st infusion on November 4th. Send out all those good wishes.  You can check out the video we recorded together if you want to hear more. The first 40 minutes are really just a recap of our spring, summer and fall fun- complete with photos and videos.  https://youtu.be/AGyUgXLHXGo On a Happy Note Rhinebeck! Sharon of Knit Style Yarns just released her first pattern- Celtic Christmas Cowl ($5 knitting pattern available on Ravelry) & kindly gifted me a copy. Thank you Sharon & congrats! I went to see Sweeney Todd at Company Theater with Mom, Terri & Emelyn. My cousin Colleen got married last weekend! She looked beautiful. The wedding was perfect. They had cider donuts instead of wedding cake! Mom & my 94 year old Aunt Florence who also has cancer, set Colleen's wedding as their goal and they were both there with big smiles and so much energy. Dancing and laughing. We are all so grateful for that. Colin and Nora whooping it up on the dance floor. Colleen & her Dad dancing in the trolley all the way back to the hotel with Dan and my cousin Joanie's husband using their phone flashlights to create a strobe effect! Oisin and Dan working to cut and stack wood. Made Oisin a batch of applesauce even though I haven't had time to teach him how to make it yet.  My cousins sent me a beautiful bouquet of flowers. Total surprise. 20 years at my day job. Dinner celebration postponed but Dan and I look forward to going to that in early 2023. I got to pick out a gift from an online catalog. I picked an Air Fryer so hit me with your best vegetarian air fryer recipes! Our contractor starting putting new railings on our deck. We attended my cousins (Pat & Kevin's) joint Surprise Costume Birthday Party. Mom, Dad, Dan and I dressed up in a Little Mermaid Theme!  We saw a local production of Guys & Dolls. Megg is a Hot Box Dancer. Oisin was a Gambler. They were both great! Quote of the Week There is the touch of November in the air, chill enough to have a slight tang, like properly aged cider. Not air that caresses, nor yet air that nips.  Air that makes one breathe deeply and think of spring water and walk briskly.   -Hal Borland   Contact Information:   Check out the Down Cellar Studio Patreon! Ravelry: BostonJen & Down Cellar Studio Podcast Ravelry Group Instagram: BostonJen1 YouTube: Down Cellar Studio Facebook: https://www.facebook.com/downcellarstudio Sign up for my email newsletter to get the latest on everything happening in the Down Cellar Studio Check out my Down Cellar Studio YouTube Channel Knit Picks Affiliate Link Bookshop Affiliate Link Yarnable Subscription Box Affiliate Link Music -“Soft Orange Glow” by Josh Woodward. Free download: http://joshwoodward.com/ Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases.

Rogue Ways
Double Helical - The DNA Enigma

Rogue Ways

Play Episode Listen Later Oct 7, 2022 15:06


DNA is the code of creation, holofractally reflected across every aspect of the Universe. Come dive in. LINKTREE: https://linktr.ee/LindseyScharmyn NEW AUDIOBOOK: https://adbl.co/3ay4dti AUDIO EXCLUSIVES on Apple Podcasts: https://apple.co/3z4ogsy NEW BOOK! The Key of Transformational Healing: https://bit.ly/3P6XuFD NEW Tees & Merch: https://bit.ly/3uIPR00 NEW COURSES to unlock your spiritual potential: http://www.rogueways.thinkific.com Musical and artistic genius of Rogue Ways: https://linktr.ee/johnnylarson

Down Cellar Studio Podcast
Episode 240: Mojo

Down Cellar Studio Podcast

Play Episode Listen Later Sep 30, 2022 45:48


Thank you for tuning in to Episode 240 of the Down Cellar Studio Podcast. Full show notes with photos can be found on my website.  This week's segments included: Off the Needles, Hook or Bobbins On the Needles, Hook or Bobbins Brainstorming From the Armchair Knitting in Passing KAL News Events Life in Focus On a Happy Note Quote of the Week Off the Needles, Hook or Bobbins Stormy Nanaimo Pattern: Nanaimo Cardigan by Tara-Lynn Morrison ($6.50 Knitting Pattern available on Ravelry or in kits on this website) Yarn: Wool Ease Thick & Quick in the Storm Front colorway Needles: US 13 (9.0 mm), US 15 (10.0 mm), US 19 (15.0 mm) Ravelry Project Page  4.15 skeins (705 grams) Started collar in September 2021. Then put it aside and didn't pick up until Friday 9/23/22 Realized I forgot decrease round before ribbing on the sleeves and had to rip those back to fix them. On the Needles, Hook or Bobbins Mermazing Socks Yarn: Hypnotic Yarn Plush Sock in the Mermazing Colorway (April 2022 Subscription Box) & mini skeins from Legacy Fiber Artz. Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Check out my Unboxing Video Here Yarn from Pigskin Party Sponsors Hypnotic Yarn/Yarnable Box & Legacy Fiber Artz- both Snack Shack Sponsors Project Bag from Anne Beady Designs (Pro Shop Sponsor) The Shift Pattern: The Shift by Andrea Mowry ($7 Knitting Pattern available on Ravelry & her website) Yarn: 3 Skeins of my Handspun Needles: US 3 (3.25 mm) Ravelry Project Page I messed up on a slipped stitch section in the decrease side, so I am going to continue it a few more times so it looks intentional, though you can hardly tell with the handspun. Portal Socks Yarn: Legacy Fiber Artz Steel Toes Base in the Portal Colorway Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Yarn from Legacy Fiber Artz- Pigskin Party Snack Shack Sponsor Woolens & Nosh Socks Yarn:  Woolens and Nosh 90% SW Targhee, 10% Nylon 3 Ply Yarn (411 yards / 100 grams) in the Sprout Colorway Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Ravelry Project Page Sprout- 10 stripe- Light yellow, peach, ballet pink, maroon, dusty blue, kelly green, tapue, lighter grass green, cream, pale green. Mini for cuffs and heels- brown with cream speckles.  Yarn from Woolens & Nosh-  Pigskin Party Pro Shop Sponsor Project Bag- Pigskin '22 Exclusive from Anne Beady Designs  Sagamore Flyover Cowl  Ravelry Project Page A take-off on my Sagamore Flyover Hat available on Ravelry & LoveCrafts.  2021 Scrappy Socks Pattern: OMG Heel by Megan Williams ($5 Knitting Pattern available on Ravelry) Needles: US 1.5 (2.5 mm) Yarn: sock yarn minis and scraps Ravelry Project Page (started in April 2021. Picked back up in September 2022) In this project, I used Helical knitting using Video Tutorial from Knitty Natty & Cate's Clasp Weft join- check out my YouTube Tutorial  by clicking here. Brainstorming Fidget Toys from Shanalines Designs-  Ravelry Link & Payhip I want to cast on all the things! Should I cast on a Wave of Change Jacket by Denise Bayron to match Mom's at Rhinebeck? $10 Knitting Pattern available on Ravelry  Top down open front cardigan mostly stockinette w/ periodic purl ridges.  Mom's is tunic length. I think I'd make my cropped to wear as a layering piece. Thinking mustard.  This blog post by Susanna Winter has a great formula to help you figure out holding strands of various weights of yarn together to equal a different weight of yarn. Beth sent me Instagram stories from FashionSchoolDropOut who made one with worsted and 2 strands of sock. Changed colors after each purl bump.  Thanks to AJ for recommending Fundamentals of Caring with Paul Rudd (2016 movie). Available on Netflix. I'm planning to watch it soon. From the Armchair The Soulmate Equation by Christina Lauren. Bookshop Affiliate Link. Amazon Affiliate Link. Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases. Knitting in Passing Take Back Bags from For Days does accept yarn. Thanks Rachel Kashani. Cost $20. They mail you a bag (takes 3 weeks to ship) The Large Bag measures 24 in x 24 in and fits 15 lbs Mail back with USPS. You will get a $20 credit to spend with them KAL News Pigskin Party'22: The Official Hashtag is #DCSPigskinParty22 Pigskin Landing Page on the Down Cellar Studio Website. Start Here Thread in the Ravelry Group Link to the Official Rules Player Registration- Google Form Check out our amazing Sponsors! Click here for the Google doc with their websites and Instagram profiles.  Check out the list of available Coupons from our amazing sponsors- Ravelry Link. Google Doc. Check out the Pigskin Exclusive Items in this Ravelry Thread Important Updates in this Episode Thanks to everyone who participated in our Kick Off Events. Beth joined us from the hospital. AJ, from South Africa, and EJ from South Korea joined us from all sorts of crazy time zones! So great to see so many familiar faces in long time friends and to also get to know some of the newbies a little better.  Tailgate Talk -ended 9/23 but you can enter for your points through 9/30 on the Points Tally Form.  Fistbumps & Fives: Send some positivity to one of your Teammates, Opponents or Commissioners. Complete this challenge anytime between 9/20-9/30 and enter on the Points Tally Form to earn 100 bonus points. You'll need a link to your Ravelry or Instagram Post for validation. Enter your points by 9/30. Check out the details in the Ravelry Group or in this Google Doc. Check out October's Coin Toss Interception hosted by Sunsoaked Yarns. Click here for the Ravelry Thread or here for the Google Doc with all the details you need. Events Cape & South Shore Yarn Haul- Thursday 9/29 through Sunday 10/2. Check out their Event Website for details.Facebook Page available here. Greater Boston Yarn Crawl– Thursday 9/29 through Sunday 10/2 Rhinebeck – NY Sheep and Wool Festival. October 15 & 16. Wool & Folk Event– October 14th from 12p until 7p in Kingston, NY.  Tickets still available. $45. 25 vendors. Podcaster Patio. 5 podcasts represented Outdoors. Food trucks and music.  CAKEpalooza: October 14 from 10 a.m. – 5:30 p.m. with ticketed & timed slots in Saugerties, NY EarthTonesGirl Falling Leaves Sock KAL runs 9/15 through 11/15 Check out this Instagram Post for details. The official hashtag is #fallingleavessockkal2022 Life in Focus Tune in to hear an update on my 22 for 2022 list.  Go Skiing 1/18/22 Loon mountain + 2 days in February Knit a garment out of handspun (from 2021)- Cowl in progress Spend at least two hours learning something new (on my own, in a class, YouTube videos etc) IDEAS FOR ME? Read 22 novels – 15 as of September Go to an art museum (travel in November- should be able to do this) Buy something a little extravagant – new skiis & bindings 1/17/22 Meet with financial planner about new investments. Emailed 9/27 Do at least 1 yoga video per month Jan, Feb, March, April  May, June, July, Sept (no August)  Kayak at one new place- NOPE Create the collage wall in my studio- purchased several items. Need to just pull the trigger. Visit Eme at school (April 2022) Try out the new trail on Grove Street -Sunday May 13, 2022 2nd Annual Nora Ephron Movies Day Laura visit in October. Maybe she wants to do this with me?  Purge & declutter the secretary Plan and go on at least 1 date with Dan that involves going at least 1 place we don't “normally” go IDEAS FOR ME? Take a vacation/staycation before August  (planned Saco trip & Northampton Concert trip for August) Buy a fabulous new dress to wear to weddings- April & September Have my car's backup camera checked out & ideally fixed- scheduled 10/12 Hire a professional photographer for family photos- emailed in Sept. Spend a weekend with Laura (in NY or MA) Go Apple Picking (on the calendar) Hang a calendar in the dining room- done in February On a Happy Note Conor's wedding (blog post available over on Patreon) Decorating for Fall Our friend Liz slept over so Dan could drive her to the airport very early the next morning. Long morning walks on the weekend. Quote of the Week A library is a medicine cabinet. What can heal one person may not work at all for somebody else. –SANDRA CISNEROS Contact Information: Check out the Down Cellar Studio Patreon! Ravelry: BostonJen & Down Cellar Studio Podcast Ravelry Group Instagram: BostonJen1 YouTube: Down Cellar Studio Facebook: https://www.facebook.com/downcellarstudio Sign up for my email newsletter to get the latest on everything happening in the Down Cellar Studio Check out my Down Cellar Studio YouTube Channel Knit Picks Affiliate Link Bookshop Affiliate Link Yarnable Subscription Box Affiliate Link Music -“Soft Orange Glow” by Josh Woodward. Free download: http://joshwoodward.com/ Note: Some links are listed as Amazon Affiliate Links. If you click those, please know that I am an Amazon Associate and I earn money from qualifying purchases.  

The Deer Gear Podcast
#28 - Helical Vanes and Arrow Wraps for Bowhunting - Does it REALLY Make a difference?

The Deer Gear Podcast

Play Episode Listen Later Apr 8, 2022 53:04


In this week's episode of The Deer Gear Podcast I am joined by Dorge Huang from Firenock and Dave Murray from Vital Limits to discuss helical vanes, offset, and arrow wraps. Do they help? Do they Hurt? Do they make any difference? Stay Tuned to find out! Connect with Dave: Website: https://bit.ly/VitalLimits YouTube: https://bit.ly/VitalLimitsYT Connect with Dorge: Email: dorgeh@firenock.com Website: https://bit.ly/3Firenock YouTube: https://bit.ly/FirenockTV_YouTube CONNECT WITH US: https://linktr.ee/TheDeerGearPodcast https://linktr.ee/exodustrailcameras http://linktr.ee/TheLandPodcast

When the Curves Line Up
2021, July 19: Helical Rising of Betelgeuse

When the Curves Line Up

Play Episode Listen Later Jul 13, 2021 5:48


July 19, 2021: Betelgeuse is making its first morning appearance or heliacal rising in the eastern sky. This episode is also available as a blog post: https://whenthecurveslineup.com/2021/07/13/2021-july-19-helical-rising-of-betelgeuse/ --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/jeffrey-l-hunt/support

Best Home-Tutors
HELICAL SPRING AND SIMPLE PENDULUM. (SIMPLE HARMONIC MOTION). FORMULA. www.besthometutors.com.ng

Best Home-Tutors

Play Episode Listen Later May 27, 2021 3:14


Thank you so much for listening to today's PODCAST EPISODE

It's Acadiana: Out to Lunch
You Are What You Eat

It's Acadiana: Out to Lunch

Play Episode Listen Later May 11, 2021 33:50


In theory, plants are a pretty simple product. The general principle of it is straightforward. You put something in the ground. Add some water, some nutrients. You wait, you harvest, you eat. Or maybe you stuff it in a wicker basket and sell it at the farmer's market.  But it's really not that simple if you want to take something homegrown and market it. We run across products all the time that — in theory — you could make yourself. But maybe you couldn't make it quite as well or as consistently or cheaply.  That's the hump to get over in taking backyard commerce to the marketplace. And it applies to folks selling produce like hydroponic lettuce or what business school types call “value added products” like an herbal tea.  Or how about manglier tea? If you grew up in a Creole or Cajun household, you know what I'm talking about. If you didn't, manglier tea is a French Louisiana cure-all made from a shrubby bush you probably have in your backyard. Traiteurs — faith healers — use it to treat all kinds of maladies. Your grandmother might have made it for you when you got a cold. It works. And like any medicine that works, it usually tastes awful. Rayvin Silas-Chevalier has figured out how to make it more than a little palatable. Her company Blackbird Botanica brews manglier tea with honey, lemon orange and cinnamon. Her recipe is so good at helping the medicine go down, she can hardly keep up with the demand on shelves at local shops around Lafayette. Rayvin comes from a long line of healers. And it was her work as doula that first got her interested in herbal brewing. Her flagship product is Brave's Brewed Manglier Tea — a Creole Immune Boosting Elixir. Homebrewing and home growing can be rewarding, especially when it's healing. But what if you want to scale up and bring that nutrition to a wider audience.  That's actually pretty tricky. Selling even lettuce on grocery store shelves takes an act of Congress — more specifically meeting USDA standards. But that's what it takes if you want to do local — bigger. And that's Kohlie Frantzen  is trying to do with his hydroponic farming concept — Helical Farms. Hydroponic farming was an “a-ha” moment for Kohlie. The set-up, the machinery, the possibilities all seemed like a perfect fit for the skilled trades in Louisiana's oil patch. Helical's top seller is lettuce, which they supply to several local restaurants. And the operation has partnered with food banks to stock pantries during the pandemic.  This show was recorded live over lunch at The French Press in Lafayette. You can find photos from the show by Kieran McIntosh at our website. Check out more lunchtime conversation about local health alternatives and healthy local food farming here. See omnystudio.com/listener for privacy information.

Two Ewes Fiber Adventures
Ep 157: It Ends in a Fit of Laughter

Two Ewes Fiber Adventures

Play Episode Listen Later Mar 10, 2021 59:38


More discussion about shots (not from a glass) and needles (not for knitting). Sorry! We finally get down to knitting, bored dogs, and new projects. We end by laughing at own ridiculousness when read in a transcript.  Show notes with full transcript, photos, and links can be found in the podcast section of our shop website: TwoEwesFiberAdventures.com. If you’d like to become a patron and support the show financially, visit our Patreon page.  Subscribe on Apple Podcasts or Subscribe on Android or Subscribe on Google Podcasts Marsha’s Projects I’m still working on the pair of socks for myself using Drops Fabel Print that I bought in San Luis Obispo. I’ve knit about 6” of my Walk Along tee by AnkeStrick and I’m using Little Fish Stitches fingering. Beginning to worry if I will have enough yarn. Spinning on and off with olive green merino roving. We had one beautiful sunny day this week that I could sit on the deck and spin. Heaven! I’m combining it with another merino I ordered from Paradise Fibers in Spokane, Washington in a dark brown called Bitter Chocolate. Making a 3 ply with two green and one brown single. I’ve spun two skeins. Swatching to make the Abington Mitts by Jennifer Lassonde as part of our Extremities Knit/Crochet Along. Using Dale Garn Helio that I got from Kim’s bag of yarn headed to the thrift store. Enough yarn for a brown and a burgundy pair. Kelly’s Projects  I finished the pair of socks for Robert!  And another Ice Time Hat! The Ice Time Hat is a pattern given to me by BostonJen of Down Cellar Studio podcast. I used two different yellow and purple variegated skeins.  Check out my project page.  Started the Iced Matcha Socks by Dots Dabbles. I’m using handspun wool mohair yarn that I spun from batts I carded. The wool is Charlotte (a gray sheep whose fleece I bought twice in the early 2000s). The mohair is a similar vintage mohair fleece that I bought and dyed.  Both of these patterns are from the designers who have donated prizes for the Extremities K/CAL.  I also started Frog and Toad from frogandcast.com.  I’ve finished Toad and now need to start Frog. Then there are clothes to make. Extremities Knit/Crochet Along This KAL/CAL was inspired by the generous donation of these patterns: Abington Mitts, Jennifer Lassonde, Down Cellar Studio Coffee Socks Collection, Dotsdabbles Designs, Deborah It ends on April 25, 2021. Knit anything for your extremities (hands, arms, legs, feet). Winter Weave Along Ends on March 31. We will have prizes, including a class generously donated by Erica at Weavolution. Ep 157 final Mon, 3/8 5:41PM • 59:38 SUMMARY KEYWORDS yarn, knit, socks, laughing, transcript, marsha, appointments, pattern, talking, extremities, vaccine, people, thought, podcast, weaving, hat, crochet, pair, fun, vaccinated SPEAKERS Kelly, Marsha   00:03 Hi, this is Marsha and this is Kelly.   Marsha 00:05 We are the Two Ewes of Two Ewes Fiber Adventures. Thanks for stopping by.   Kelly 00:10 You'll hear about knitting, spinning, dyeing, crocheting, and just about anything else we can think of as a way to play with string.   Marsha 00:17 We blog and post show notes at TwoEwesFiberAdventures.com.   Kelly 00:22 And we invite you to join our Two Ewes Fiber Adventures group on Ravelry. I'm 1hundredprojects,   Marsha 00:29 and I am betterinmotion.   Kelly 00:31 We are both on Instagram and Ravelry. And we look forward to meeting you there.   00:36 Enjoy the episode.   Marsha 00:43 Good morning, Kelly.   Kelly 00:44 Good morning, Marsha. It's Friday. Yeah. I'm not sure Friday means much to to a lot of people during a pandemic, but it means a lot to me.   Marsha 01:01 Yeah, it doesn't really mean... it doesn't mean... Friday, in fact, well, yeah. Friday doesn't mean that much to me anymore. But yeah, if you're retired, yeah. And you know, Ben does his own school thing. Idon't... I'm not involved in that. And and   Kelly 01:14 I hope I should hope not.   Marsha 01:16 I know at the age of 23. I should not be involved in it. I'm not. Such a relief.   Kelly 01:23 I have students whose children are involved in their college education, helping them but   Marsha 01:31 Oh, yeah, yeah,your children appearing in zoom meetings and stuff. Zoom.   Kelly 01:35 That too. Yeah. I have a couple of students that come to my office drop in hours, and their children are usually in the background, or you can hear you can hear the schooling going on in the background, while the children are on their own zoom, their own zoom meeting. So. So yeah, I have a class for kind of a beginning level math class, you know, basically no prerequisites. You know, anybody can take it. And some of those students have their kids helping them. "I got confused, and I watched your video, and then I got my kid to help me."   Marsha 02:14 So yeah, it's a family, a family affair. Sweet.   Kelly 02:20 When parents talk about, you know, having school and kids and all of that, I always, I always tell them how, how much I think it's great. Because it's such a role model for their children, you know, that you continue to learn, but it's rough. I can't imagine the students I have, who are, who are parents who are going back to school, who are working, who are helping their children do their school, I always admire, you know, the parents who are coming back to school and the amount of work that they have to do. But in this pandemic, it's just been, like magnified. Yeah, very impressive. Yeah. their commitment to education.   03:01 Oh, yeah.   Marsha 03:02 It's a struggle, but it'll be worth it in the end, you know?   Kelly 03:07 Yes. And some of us in the struggle, I'm not including myself in that us really, some people in the struggle will be able to talk about it in the same way that, you know, of the sacrifices that people made during war time. Or, and some people are not, are not stepping up in that way. I sort of wonder what it would be like if they were having to live through war time, or, you know, like, the Greatest Generation they talk about, that, you know, lived through World War Two and made all those sacrifices. And our society is not quite measuring up, I don't think, to that standard.   Marsha 03:47 Well, I don't know. I mean, well, you mean, in terms of wearing masks?   03:52 Willing make a..? Being willing to make a sacrifice?   Marsha 03:55 Oh,   Kelly 03:56 for the good ofeveryone.   Marsha 03:59 It may sort of depend on where you live.   Kelly 04:01 Yeah. Yeah.   Marsha 04:02 You know, because if you're talking like masking specifically, everybody masks up. In fact. I mean,here...   Kelly 04:10 what I'm specifically talking about here, I guess I should I should be clear. What was specifically talking about here in California, is all of the complaining about teachers not going back and the teachers unions not wanting to go back and parents can't get their kids back in school. And, like, I understand that, I understand that it's hard. But you don't get to have your same old life. Right? I mean, this is what I want to say to people, right? You don't. None of us gets to have the same life we had last February, none of us does.   Marsha 04:16 My mind was going... Well. And I say even with the vaccine, it sounds like we're not going to have our same lives, right?   Kelly 04:55 For a while at least.   Marsha 04:56 it's going to be a different version of our of our of our same You know, yeah, so,   Kelly 05:02 I think I talked about the whole, you know, push to get teachers vaccinated which is happening, and that's really good. But what was being said about what was happening and what was really happening were two different things. And so it makes it seem like, you know, well, all of you teachers are all vaccinated. So why aren't you wanting to come back? Well, we're not all vaccinated. I have my appointment, though.   Marsha 05:26 That's good.   Kelly 05:27 Yeah. Quick shift of the subject to be more positive. Okay. Just to be clear, I was finding myself going to an ranty place and I don't want to do that. So   Marsha 05:45 well, just before you shift, let me just say here, like, I think that where I live in Seattle, everybody's wearing a mask. And so like, it seems to everybody's very compliant. I'm not going to restaurants. Stores that I've gone to, I always go in and say like, you check, how do you want me to do this? Everybody seems very on board with this in my world. In fact, so much so like, when I take Enzo for a walk, I always bring a mask with me. Because even though I don't come in contact with anybody, everybody's masked up even walking through the neighborhood. Yeah. Which I don't even know how necessary that is. But I think it's sort of it's becoming kind of a sign of solidarity, you know, but anyway, yeah. Yeah. But yes, on to more positive things. You're getting your vaccine. Yay.   Kelly 06:27 Yeah, yeah. So my first dose is the 13th. And honestly, it felt like I was trying to get concert tickets. We had multiple alerts coming out on the faculty email at work, saying, Oh, I just checked the site, and they've got vaccine appointments, and then I go and no appointments. And when I got up in the morning, I get on the computer, I always check and I go through the whole thing. And the dumb thing is that you had to go through the whole process of putting in all this information. Not all of your information, but you had to click a whole bunch of places, just to be told that there were no appointments available. Like, okay, I'd rather on the very front page, right when I, you know, right, when I click on to the front page, you tell me there's no appointments available. But anyway, I do that every morning, and nothing would be available. And then the other morning, the other morning, I got on and I checked, and there was nothing. And all the dates were old. And I mentioned to Robert Oh, they haven't even updated this website yet. You know, they've still got all the old, all the old dates, they don't have the newest dates. And so then I went on to do my you know, play on the computer, read Ravelry, read my email, that kind of stuff. And I'm reading my email and one of my colleagues had emailed that there were now-- there was-- our county office of education was hosting a vaccine site. And so I went to that. So get this. She, she so it came on, it came on the screen, sometime in like a 10 minute timeframe of when I had looked and when I got the email that it was there. So I went there. It was I mean, at most 10 minutes after it had been live on this website. They had multiple appointments, like six to eight appointments every four minutes, from 10 until 4pm.   Marsha 08:32 Mm hmm.   Kelly 08:32 So that's a lot of appointments.   Marsha 08:34 Yeah.   Kelly 08:36 And I made mine. So I got it. I was like, Okay, I'm going to pick a time that has, you know, five appointments available as opposed to two because I don't want to be cart-jacked. You know, I don't want to get to the end and find out my appointment was already taken. So I do that. And then I texted some other people to let them know. And then I went back to look and they were all taken.   Marsha 09:01 And you were cart-jacke? I mean they took that one.   Kelly 09:05 Oh, no,no, no, I got mine. Okay. But I I texted and then I went back to check on it to see to see like, how many more appointments there still were, and nothing! Okay, so like within 15 minutes. All those appointments, you know, eight, five to eight appointments every four minutes, from 10am to 4pm. All of those appointments were taken within probably 15 minutes. Wow. It felt like I was... or like I was trying to get yarn from a super super popular dyer! Wake up in the middle of the night when the update happens and like in the early days, the Wollmeise I think was one of them. Yeah. You know, people used to get up in the middle of the night to try to get Wollmeise yarn. And anyway, I felt like that as I was trying to get my point. I've never been this excited for a shot in all my life, not even a shot of bourbon!   Marsha 10:07 So then, so you'll have, I'm assuming this is the two part vaccine.   Kelly 10:14 Yeah, yeah.   Marsha 10:15 So then how do you know when you get your second one?   Kelly 10:18 I don't know. Yeah.   Marsha 10:20 Okay, how that's gonna work?   Kelly 10:22 I'm not sure how that's gonna work. Yeah, I'm assuming that the same site will have the second round. And then all of us who got appointments for that first site will go to the second site, go to the second round at that same site, but I don't know for sure. I don't think we know for sure.   Marsha 10:41 I was gonna say the thing about the websites, too. So let me just say, you know, in the state of Washington, I don't know what this is, all states have this. But we have Find Your Phase where you can go and find out. And you know, I'm not...I'm not eligible yet. But I went back. They say, well, they will, they will email me when I'm eligible. And I've not received any notification. So I thought, well, I'll go back and to see where I am. Maybe there's more. Because it said, when I when I registered for it, they said they don't know when my category would be eligible. No information, check back. So I thought I'll go check back. You have to register again, there's no way to go in and just log back in and find your own status, even though I've registered. And so this is a long way of saying I think they've... they've thrown these websites together as quickly as they can. And they didn't have I think... Normally with websites don't they go through for companies, they go through testing, right? Everybody uses them to check them all out. I don't think they've had any time to do that. And so there's problems in the system. Yeah Because I have no idea. You can't... Right now, I'm sure if anybody lives in the state of Washington, any of our listeners, they can tell me what's really going on but I couldn't find my status in there. I just had to reregistered again. So and then just add to all of this hearsay, rumor, confusion. Um, my brother registered in Find Your Phase and never got notified. But he's he has medical insurance with Kaiser Permanente. And so he went to the website, and he just started poking around and, and he was able to make an appointment through their website to get the vaccine. And he's never been notified that he was eligible by the state of Washington. Yeah. So I don't know. And he said, also their website, too, again, I think that they are doing the best they can sort of getting something in place, right? But he said that there isn't, like, on the website, if you want a vaccine, click here and make your appointment. He said, You have to dig down through the site, you actually have to say that you want to make an appointment to get like a flu shot or any kind of shot. And then you have to go through the and then it gets you to the part where say what I want is the COVID-19 vaccine.   Kelly 12:33 Yeah, like they should have just a big button right on the front, a big button that you push to...Yeah, right. So I bet you're right. I mean, I'm complaining.   Marsha 13:08 No, I mean, I mean,   Kelly 13:10 it's something that had to be put together quickly.   Marsha 13:13 Well, and I should say cuz I'm not... I have no idea. Now. The President came out two or three days ago saying that pretty much everybody who wants a vaccine will have it by May. So I think I will get it soon. I mean, I just it's just a matter of being patient. But I will say again, rumor hearsay, guessing, all this. It is interesting like people posting on Facebook or Instagram that are getting the vaccine. There's somebody who posts on Facebook, I know who posted that she was getting the vaccine. And as far as I know, she doesn't meet any of the criteria-- multi generational household, age, underlying health, as far as I know. And so like, how did she get it? I don't know. It's like, you know, let it go. Just let that go.   Kelly 14:08 It's possible there's something you don't knowabout?   Marsha 14:10 It's possible there's something I don't know. Because like, it could be an underlying health condition that I don't know about. So. So it's not about-- you can't sit there going like, well, how come they got it? You know, but yeah, that's-- Yeah, we're human. And that's where our mind goes, right? But it really, you know, vaccinate as many people as possible it doesn't really matter even.. you know?   Kelly 14:33 I'd be and in my thinking,...Gosh, we've been on this topic for a long time. Sorry, everyone.   Marsha 14:39 Yes, I know.   Kelly 14:40 But my thinking you know, at first was well, I'm not in contact with anyone. I'm not teaching face to face yet. I don't really need to get the vaccine. You know, I wasn't too worried about jumping.... I wasn't sitting on the computer like it was a rock concert that I wanted tickets to or you know, Hamilton or something big. Cuz I thought well I'm home, you know, I'm not teaching face to face, I'm not going to be teaching face to face in the fall. I don't have to rush. But what you want is everyone, everyone who can, to get it.   Marsha 15:13 Yeah,   Kelly 15:14 Everyone who can get who can't who can, by whatever means really should get it because that's how you get immunity in, you know, community wide, right. So in the mathematics, there's an interesting-- there was an interesting article about mathematical modeling. And the mathematical model was, what if we do it in phases versus what if we do it as whoever wants it, come and get it? And it actually was more effective in the mathematical modeling, to make it available, you know, to make whatever was available available to whoever wanted it.   Marsha 15:52 I know, that's what I was kind of wondering if that would actually make more sense.   Kelly 15:55 It was, mathematically, it was more effective. Yeah. But politically, you know, like, I'm getting the vaccine, even though I'm not going to be back in the classroom. Robert goes to work every day. He doesn't work directly with the public, but he goes to work every day, and he's not eligible yet. Yeah. But politically, I mean, they're not distinguishing between educators who are going back to the classroom and educators who are not, it's just easier not to do that. And they, you know, and the the political reality is they needed to make sure that educators got vaccinated because there's such a pressure for our schools to reopen the K 12 schools to reopen. So anyway, yeah, this is a long topic. We're probably, we're probably, we're probably treading on the boundaries of what our listeners are wiling to listen to   Marsha 16:46 people are gonna be listening to this walking the dog driving the car going. "Oh, for goodness sakes, stop talking!"   Kelly 16:53 Where's the knitting?   Marsha 16:54 Where's the knitting? Well, yes, while we wait... So anyway, patience is a virtue. I will get mine soon. I I'm looking forward to it. My vaccination. I'm excited. So anyway, and grateful that we have one. Yeah, pretty speedy the process.   Kelly 17:12 Yes,so...and apparently CVS, this part of the email I got this morning. The CVS website is already doing appointments for the Johnson and Johnson one shotvaccine. So all right. That was cool to see. Yeah. That's a lot of very fast science.   Marsha 17:30 Yes. Yeah. Okay. Ah, so we talk knitting?   Kelly 17:37 Yeah. That's what they're here for. Right?   Marsha 17:43 Yeah.Let's give...   Kelly 17:43 Sorry, you guys!   Marsha 17:44 Let's give them what they want!   Kelly 17:46 Yes.   Marsha 17:48 Okay, so how about you? Do you want to talk about your projects?   Kelly 17:51 Sure, yeah. Okay. So I finished Robert's socks. They turned out really nicely. I'm actually Oh, I'm calling them finished. And I'm actually weaving in ends right now. But, but they're finished. And I've marked them as finished in the project page. He hasn't worn them yet, because I haven't woven in ends. But he tried them on. I did end up making the toe of the first sock bigger than I had done before. The look so funny! I, I have a picture of them. And because of the toe is made from my hand spun it's thicker. It's a little-- it's not quite fingering weight. It's a little bit heavier than that. Plus, it's a, it's a denser yarn. They have the most bulbous toes, but they're not pointy. So he loves them. And I'm like, they look so big. And he said, No, no, they look perfect. So   Marsha 18:51 yeah. Are they comfortable? The   Kelly 18:52 Yeah, he likes them.   Marsha 18:53 The big poofy toes. Yes, he has room for his for his toes. So they're not   19:00 pointy, and they and they are big enough, but they do kind of bulge out while the sock is ribbed. So that's part of it, too. So the ribbing sucks in the foot of the sock. And then I added stitches when I made the toe because it was too dense and stiff and tight. So anyway, yeah, it's they're interesting looking.   Marsha 19:25 Well, you'll have to share a picture of them.   Kelly 19:27 So I will Yeah, the leading men fiber arts yarn is really nice. I'm gonna get myself some more of this. Maybe not this color. I don't know. I like this color! But it's just a really nice sock yarn. This is-- I think this one might be bfl sock, I can't remember now. But it just it feels nice. It was nice to knit with and the put up is very large. You get a lot of yarn in a skein of this.   Marsha 19:59 [Laughing] Okay. Sorry, I'm interrupting. I'm just looking at the   Kelly 20:04 you see what I'm talking about?   Marsha 20:05 Yes. Yeah.   Kelly 20:10 The toes are quite bulbous.   Marsha 20:11 Yeah, but they look comfortable.   Kelly 20:14 Yes. And they aren't--I mean, they aren't baggy when he wears them. They actually do fit it. Yeah, it's really more of a function of the, the ribbing on the foot, making the ribbing skinny   Marsha 20:25 It's when they're lying in repose. [Laughing]   Kelly 20:31 But they don't have pointy toes when you fold them top to bottom. [laughing]   Marsha 20:36 Yeah,   Kelly 20:37 Speaking of starting socks, I did start the Iced Matcha socks by Dots Dabbles. And the yarn I'm using is a handspun. It's a gray. It was... the sheep was Charlotte and I bought her fleece a couple of times. It's the same fleece that I used for the funky grandpa sweater.   Marsha 20:56 Okay.   Kelly 20:57 And I finally had used both. I bought two of her fleeces two different years back in the early 2000s, late 90s. And I finally spun up the end of it a couple of years ago with some mohair. So these are mohair wool. It's only a two ply. So I don't know how hard wearing they will be. But the mohair should help. It's probably a little bit thicker than a fingering weight. But not not, not so much bigger that I won't be able to use like a size one needle. And I usually use size zero, I'll probably use a size one. And anyway, I decided to make the iced matcha sock pattern. It's like ribbing, you know, has kind of a ribbing effect, which I like. And then it has a little bit of detail, but not so much detail that I won't be able to knit on them during school meetings and that kind of stuff. So and then I'm going to start another pair of of socks. I don't know which ones. I think maybe one of the cabled pairs from either from this collection, or maybe one of the Louise Tilbrook. I have quite a few of her patterns. And I have one pair of socks that I really like that was one of her patterns. So I might make one of hers. They're very involved. So, so the the Iced Matcha of socks will be sort of a medium-involved. Not not super involved, which will be good. So I'm enjoying, I just barely started those. So that's there's not much going on there. Except basically a cast on. I did also finish another Ice Time hat. The first one that I made I don't remember if when I talked about it last. But the first Ice Time hat that I made her pattern. This is from the pattern is by Jennifer Lassonde, Down Cellar studio, BostonJen. And she gave me as a gift, a copy of this pattern. And so I thought, oh, I'll try it. And I mean, I used two variegated yarns. And I looked on the pattern because it came out a little small, my gauge, you know, I usually knit pretty tightly. And so I thought, Oh, this is a little small. But then I looked on the pattern, and she has as the head circumference 18 inches, I think, which is smaller than what I normally do for a hat. Plus the cross stitches, I think have a tendency to make it tighter. Yeah. And plus, it's like a beanie.   Marsha 23:41 Yeah.   Kelly 23:42 And so, so I thought, Okay, well, this is good, because it's the size for a kid and that was my plan. But I want to make a bigger version. So first, I was gonna, I was gonna just add, you know, like, one pattern repeat or two pattern repeats. And, and then I thought, well, it's when -- when you do the decreases, you divide it into fou. Into four groups to do your decreases. And so like the decreases make an X on the top of the hat. And I thought, okay, that's going to make those four groups different sizes.   Marsha 24:18 Yeah.   Kelly 24:19 And I just thought, you know what, I'm just going to add four repeats, because 18 inches is small to me for hat circumference.   Marsha 24:26 Mm hmm.   Kelly 24:27 So that's what I did made it a lot easier to do the decreases and then made the slouchy version, which is more like the kind of hat--again, this is nota hat that I'm going to keep-- but more like the kind of hat that I wear. Doesn't smash your hair as much, you know, hat head. So anyway, I really like it. It came out really great. And so now I have a pair like a mother and daughter a pair of hats.   Marsha 24:57 Sweet   Kelly 24:58 Yeah, in purple. purple and yellow.   Marsha 25:02 So I don't they're not in your project page yet, though, right?   Kelly 25:06 Oh, you know, the first one I finished a long time ago. And I just put the second one in the same. So it's farther down on the project page. Oh, I'm, I'm suddenly distracted, because there's someone on the roof right outside.   Marsha 25:19 Oh, really?   Kelly 25:22 We had the roof put on. And then they had to replace some flashing and replaced--we have these like scupper boxes that the water goes down. They replaced those. And so apparently they're here to do something else with with the flashing. So I suddenly looked up, and there's a stranger on my roof. Right outside the window. Because the   Marsha 25:49 and he's wondering why you're talking to yourself?   Kelly 25:51 Yes. [laughing] Because the kitchen window or the kitchen roof is right outside the vanity area where I record so anyway. Life at the Locke household!   Marsha 26:03 Yes.   Kelly 26:05 So both of the designers, dots dabbles of the Iced Matcha socks and Jennifer Lassonde from this Ice Time hat have donated prizes for our extremities KAL that we'll talk about. So it's fun to be using. It's fun to be using their patterns. Although a hat does not count for the extremities KAL.   Marsha 26:25 Yes.   Kelly 26:27 I looked it up. It's not an extremity. several I looked actually I looked at several dictionaries. When you you know, I looked at I put in extremities and then I looked under several online dictionaries. And none of them included heads. So   Marsha 26:46 it's a headless knit along.   Kelly 26:50 Exactly! I started something really fun.   Marsha 26:54 Oh, yes.   Kelly 26:55 Yes. Frog and Toad. Oh my gosh. So cute. And you know, I was talking about socks. The socks being only medium-level involved. Then I started with toad. that's involved! Okay, that kind of knitting is involved, right? I mean, it's kind of sorta like your rabbit.   Marsha 27:20 Yeah, lots of increases, decreases. And it's just like a blob until you... it starts. And then they begin to take shape. But originally, initially, you don't really know what you're making,   Kelly 27:31 Right!   Marsha 27:31 you know, it's the legs but what?   Kelly 27:34 It's pretty much one piece, you do have to go and add the arms at the end. It's pretty much one piece. So that was good. You don't have a lot of sewing to do for the extremities. But you do have to do sewing for the eyes. Okay, and you do, you do like afterthought heels where you cut your knitting to make the holes for the eyeballs.   Marsha 27:58 Oh, Dear!   Kelly 28:00 Yeah, so it reminds me of... I looked at the pattern and it reminds me of when I did the afterthought buttonholes. Because it's a real small thing that you open up, you know, you cut open a piece of your knitting. And   Marsha 28:14 so this type of knitting I have to say I'm, I always think the same thing. The mind that can think this way. , To create these very--just adorable and just so creative. I mean, to think like, they can figure out you have to put your decreases here, your increase there and your short rows here and like how they can do all that? How many frogs did the designer make to get the final pattern? You know?   Kelly 28:45 Right.A lot of experimentation.   Marsha 28:47 Yeah.   Kelly 28:48 In the creation process. In fact, her website is frogandcast.com. So as of today, March, what is it March 5 2021. The front page of her website is this little bear and the whole article is about about how she, how her design process for this bear worked. So I highly recommend it as a very interesting read. And it's also a cute pattern. But I'm not going to make this bear I'm going to stick to my Frog and Toad. So I've made toad. And I'm going to.. I want to start on frog soon. I'm gonna wash him, the toad, because I'm using the Ruama. Now I can't remember how that is pronaunced. Finnulgarn   Marsha 29:42 Oh, right, right, right   Kelly 29:43 that we bought. So this is yarn that Marsha and I bought at stitches one year because we, I was taking the Argyle sock class and so at lunch during my class, during a break, and Marsha and I went down to the floor of the marketplace. And we just started putting color combinations together. And it's Ruama Finnulgarn is what I'm using. The frog is going to be our Toad is in a brown color. And then I have another one of these Ruama Finnulgarn that is alpaca and I have a green, like a limey, goldie... Lime is not the right word, kind of a goldy, green color, kind of an avocado. You know, like 1960s, avocado, refrigerator look or something. Anyway, it's kind of a goldy green that I'm going to use for Frog. And I have the books. And I've been getting the books out and comparing the pictures on the book to the My yarns and stuff to to try to get the right combination. So but this yarn is the the one I use for Toad that doesn't have the alpaca in it is a little bit. It's toothy. You know, it's a woolly wool. And so I know those soften up when you wash them, so I'm going to block him before I stuffed him. And also the yarn will kind of bloom and help keep the anything is stuffed, you know, help keep the stuffing from showing. So yeah, but I'm using size zero or size one needles. I think I'm using size zero and the let me just double check. Yes, it calls for size one. And I'm at I'm using a size zero needle because my yarn is a little thinner. The pattern calls for a DK yarn. And I'm using a thinner yarn its more like a sport.   Marsha 31:43 I'm sorry, it calls for DK and size zero needles?   Kelly 31:47 It calls for size one needles.   Marsha 31:50 Oh one, ok.   Kelly 31:50 and it has a I mean,   Marsha 31:52 that's still that's really small. Because it's you want to have a really dense, right?   Kelly 31:56 Right, , so the stuffing doesn't show. Yeah, so anyway, I went down to size zero. And actually it was worked out well, because the size zero needles that I have are short. And the size one needles were longer. And it's so tiny, that it's really nice having the I don't know, they're just like maybe four inch needles, double points. They're they're small. They're small double points. And, and I don't use them. I can use them on socks. Like I bought them for socks. And I use them for socks for me. They're not my favorite sock needles, because I like using the wooden ones. But I can use them for socks for me. But for socks for Robert. With 72 stitches. They're just too, they're too short. Yeah, but they're perfect for this. I think magic loop would work. You know, you just have to keep track of where where she says to place the markers. Yeah. So that you can make all the all the little adjustments. Yeah, but super fun. His little fingers! You do little you do on his on his on his hands. You do little PicoT bind off. So you get little fingers. It's so my gosh, so cute.   Marsha 33:20 Again, Igo back to what I said. It takes a certain kind of mind. Yes, like amazing mind. This kind of stuff   Kelly 33:27 His little knees. He has nice has a little frog legs have little knees. So very fun. Very fun. I can't wait to start Frog this weekend. I'm hoping I'm hoping maybe I can have I can have them done by Easter would be kind of a fun thing to do for to give to Faye for Easter. So yeah, that's kind of my that's kind of my plan. We'll see if I am able to do it. But but that's what I'm hoping. fiddley definitely worth it. So that's my, that's the extent of my projects Marsha.   Marsha 34:08 Well, and I just have to ask the the, the Afghan the Oh,   Kelly 34:14 I have been working on it. The last the last time we recorded I hadn't done any significant work on it at all. But I have been working on it. Now I've made probably maybe five of the squares. Not the big octagons. But the smaller, the smaller ones that can connect and kind of... I made about five of those. And then I made another I have I have done one of the octagons but then.. I was... One night I was just focusing on something simpler. And so it's basically just a granny square. And then it has an edge that has a little bit of detail something a little more complicated. So I was just doing the basic granny square part and I did about I did about five of them and then I started...Another day, I picked them back up and started doing the outer edge of each of the squares. So yeah, I made made some progress on that. So maybe sometime in the late spring, I'll be done. I'll be done with that one. But I'm not going to make any promises.   Marsha 35:15 Yeah. Yeah. Never make promises.   Kelly 35:20 So what about you?   Marsha 35:21 So my Walk Along Tee, I've knit about six inches of the body. And I love the technique that we have discussed the Helical, right, we discussed? It's, it's great. There's some times when I get to the... there's fake side seam on the sweater and where you do you hold the yarn in front, and then slip the stitch through the back loop. And sometimes if you have any details, something like that, that's just not straight stockinette then you have to do a little fiddling around. Yeah. So like, as I said, in previous episodes, you know, this would not work for cables, or Yeah, this technique, it just has to be stockinette. But so I'm, that's just sort of my knitting when I watch Netflix. I just go around and around and around and around on them. I think you do about... you start doing increases on the way down. And I think I talked about this before, I'm not sure if I'm gonna put all of them in it. It ends up being a total of 20 stitches, which is fair amount, so I may not put all those in. I'm also beginning to worry about if I'm going to have enough yarn.   Kelly 36:37 Oh. Another one of those   Marsha 36:41 I know. It could be just illusion.   Kelly 36:44 Yeah, yeah.   Marsha 36:46 Because I have now... I had three skeins which I divided into half, right. So I had six cakes. I've used up two cakes. And I am probably halfway through the second set of two cakes. And I'm six inches of the body. And then I also have to do sleeves. So I-- but I'm going down to-- we're going down to Seabrook. I think we leave the 13th. So and that's where I bought the yarn at the string theory yarns in Seabrook, Washington. So I'm, when I'm down there, I'm going to have a better idea and I can maybe pick up another skein. I'm hoping I don't have to, but we'll see. Anyway, so I'm making progress on that. And I've been spinning on and off on the olive green Merino roving that I have that I'm combining with the dark brown, that's called bitter chocolate. And I've I had made two skeins and now I'm just filling up the bobbins again, so I filled the two green and now I'm filling up the brown bobbin. So I had-- it was-- we had a couple of nice days this week. And so I think it was Wednesday. It was nice. And I just sat on the deck. My new deck.   Kelly 38:13 Yeah.   Marsha 38:15 And spun. By the way, thinking that I was sitting out there spinning, Did you see my Instagram post of Enzo, staring at the dog.   Kelly 38:26 Yes. Yes.   Marsha 38:27 Isn't that the funniest thing that was so cute. Anyway, if you don't know what I'm talking about, go to my Instagram. And you'll see the picture of Enzo looking at the neighbor's dog. But the neighbor's dog is in the window peering out and they stare at each other for a good 15 minutes. It was pretty funny.   Kelly 38:45 I feel bad for Bailey because I think she's, I mean, she spent a good a good part of her life before she came to live with us living at a dog boarding kennel right? Doggy daycare and boarding kennels. So, so she was around other dogs all the time. And now it's you know, it's just her. And we have neighbors and they have... one of our neighbors has dogs that they fence fight, which I don't like so I keep her away from that. But the other neighbor has a lab that sometimes I can't find her in the backyard and I go looking for her and she's down at the fence and they are just like nose to nose at the fence talking to each other. Like, you know, not barking. Just like somehow communing. They're like keeping company with each other next to the fence. I feel like ohhh.   Marsha 39:36 I was gonna ask that, put this question out to people and to our listeners later on in the podcast, but since we're on this topic, I'm just going to mention it. Because Enzo has been acting really weird recently. I've been doing long walks, I take him out and he just drags towards the end of his walk. I have to pull him along to get him home. And he's very lethargic. So I thought and I was like.. I wonder if I had to take him to the vet, you know, he's not it. Maybe there's something wrong with him. I finally thought, I think he's bored.   Kelly 40:08 Mm hmm.   Marsha 40:09 His life is basically sleeping around the house while I do things. One long walk during the day, and then back to sleeping around that house.   Kelly 40:16 Yeah, he doesn't want the walk to end.   Marsha 40:19 Yeah, that's what I'm kind of wondering. And so I, I'm varying the route. I also am playing with him every day because I realized I wasn't playing with him. And Ben doesn't live with me now who would have time playing with him. So I, every day I take, I either chase him around the house, chase him around in the backyard, which he loves. Or I, the other thing I do, which he loves is that down in the basement, I take the ball and he stands at the top of the stairs, I throw the ball up to him, and then he kicks it, he knocks he pushes it down the stairs. And then I throw it back until we do that for about 40 minutes, 45 minutes, depending on how long we want to do it. And then I also decided to get him back into agility. But I'm having a difficult time getting him into class because I think so many people have dogs now. I went like all of the... We've done all the obedience classes, but they're all full till April or May. And so I signed him up for agility, but I can't get in until I think the end of April. Yeah. So I'm going to put it out to listeners if you have any ideas what to do to keep him... because he does seem depressed, kind of or bored.   Kelly 41:30 I'm going to give a suggestion. I am interested to hear what people have to say, but I'm going to give a suggestion. tricks. Teach him tricks.   Marsha 41:40 Oh, yeah.   Kelly 41:41 Well, you took a class, right? You did a trick class.   Marsha 41:44 Yeah. But I can't get into it now. So. Oh, but I can just do it on my own.I don't need to go.   Kelly 41:51 Yeah. So I mean, yeah, you know how to, I mean, you have some ideas for how to teach some of this stuff. But it's kind of fun. Is it a little more entertaining? I'd do that, at least for me, it'd be a little more entertaining than throwing the ball up the stairs for 40 minutes. Yes, for the human part of the partnership, it's more interesting   Marsha 42:13 well and use his mind more you know, I because that also, you know, he just needs to use his mind. But like, my brother came by yesterday said what's wrong with the dog? And so like he saw I was like, okay, you're here. He's usually excited. He's super excited to see Mark. But he was excited and then like, laying on the sofa. And then Mark came back in the house and he didn't even get up off the sofa. I have a towel down on the basement sofa and doesn't even get up to the greet him. He's like, That's weird. I mean, cuz he usually... Like they say poodles are smart. I sometimes wonder because he's super excited to see you. You go out to the garage, you come back into the house, and he's like, Oh, you've been gone. He's so happy to see you. Like literally two minutes, but, okay. Yeah, so anyway, people, listeners, if you have suggestions for how to get my dog, I don't think he's really depressed. But I think he feels like he's depressed and bored. And like the rest of us in the pandemic, you know. But anyway, yeah, so I'll go back to projects. so I've been spinning and I'm enjoying that I just find the spinning so meditative. And just that one day where I was able to sit out there on the deck was so nice in the sun. It just sort of gives me hope that spring is on its way. And then I, as we're talking I am swatching to make the Abington Mitts by Jennifer Lassonde and as we talked in... that's our segue into our, the knit along. But I just tell you, the yarn I'm using is Dale Garn Helio.   Kelly 43:53 Is that like a Dale of Norway yarn?   Marsha 43:54 Oh, I'm sorry. It's it's a Heilo. It's H E I L O, and it's a, I believe it's DK weight, which is what is required for the mitts.   Kelly 44:04 Something from your stash. Okay. Your Spirit yarn.   Marsha 44:07 No, no, it's not from my stash. It's from Kim's stash. I went and had dinner with her one night and she had a bag of yarn that was going. She had gone through her stash and she had yarn that was going to the Goodwill. And I said do you happen to have anything that's this weight because I don't need a lot for the mitts and I don't really want to go out to a store so... and I didn't have... I have DK weight but I didn't have anything that was not painted. I want a solid or semi solid. I thought it would look better with this pattern. And so she had this yarn, a whole bag of this yarn in two colors. The one I'm going to use is kind of milk chocolate color, brown, like a natural color. And then also she has another color in here a kind of a burgundy. So I think there's another yarn I can make two pairs, one in each.   Kelly 44:59 Oh, that's fun!   Marsha 45:01 So anyway, I'm swatching for that. And so for our knitalong, so we should talk about the knitalong   Kelly 45:08 So we are having an extremities knit along, and it was inspired by two offers of prizes. One is the Coffee Socks Collection that I already talked about, by Dots Dabbles Designs, Deborah. And the other gift that we got-- offer of a prize--was the Abington Mitts that Marsha is making. And so with these prizes when they came at the same time, and one was for feet, and one was for hands, and so we just decided, oh, let's have an extremities knit along/crochet along so you can knit or crochet anything for your hands, arms, legs, feet.   Marsha 45:45 We've had lots of discussion about this, but it's not your head. Because Kelly did lots of research and your head apparently is not   Kelly 45:55 according to the authorities on the internet [laughing]   Marsha 45:58 Yes. According to the internet, your head is not an extremity!   Kelly 46:02 That's no no hats in this time. Yeah, but legs, feet, arms, hands, you know, there's lots of lots of possibilities there. Mitts, socks are the most...   Marsha 46:15 And even though we're saying it's called a knit/crochet along you can weave, you can macrame.   Kelly 46:24 Okay, I don't know macrame sock? That   Marsha 46:28 Yeah. Interested in any you know, like any? We were also talking in the last episode, what is it called the   Kelly 46:35 Nalbinding. Now, that's how you say it? That's a that's a close facsimile of how it's pronounced at least. Oh,   Marsha 46:45 you know what I think would be really cool. Do you know those lace the little lace gloves that Ruth Bader Ginsburg would wear?   Kelly 46:53 Yeah,   Marsha 46:55 That'd be really fun to make.   46:56 Oh, you know, as we're sitting here, I'm sitting in the vanity area of our spare bedroom. And at the vanity table normally... not right now because I move everything when I want to record. But at the vanity table, I have a little, one of those little vanity mirrors with perfume bottles. And then I have a pair of crochet gloves. Do you remember Marsha when I bought those at the antique store?   Marsha 47:24 Yeah,   Kelly 47:25 I have no idea how old they are. But they're teeny tiny still little crochet stitches. And they have the little buttons. They're long gloves though. They go up your arm and they have the little ...they have the little buttons and the buttons are crocheted. And the little button loops are all crocheted. The button holes don't go all the way up the gloves. Like the whole gauntlet part of the glove doesn't open up. There's just a section of buttonholes. Yeah, that would be fun. A knit or crocheted set of fancy, old fashioned.   Marsha 48:01 They were kind of like fishnet kinda.   Kelly 48:04 Yeah. Like afternoon tea gloves.   Marsha 48:06 Mm hmm. I'm as we're speaking, this is bad podcasting, but I'm just looking at online and there's like a, there's a crocheted pair. From J and P coats. It looks like it's very old because it's a black and white photo with an old car. Okay. I don't know if they're Yeah,   Kelly 48:25 that's a that's a company that makes like the crochet cotton. Yeah. Oh, that would be fun. Well, and you know, the other thing that I thought of is our we had bought the silk to make silk socks. Last year at Stitches. I haven't started those yet either. But I'm gonna-- I'm gonna stick to the socks that I have for right now. But yeah, the mesh gloves. There's there's a lot.   Marsha 48:50 We'll search, Yeah. And apparently you can buy this on on Amazon. It's not that old a book. It was published in 2009. I guess that is old. Well, no. That's right.   Kelly 49:03 I'm thinking of like, gloves from the 1950s or something.   Marsha 49:08 Yeah, that's what it kind of looks like but it's a it's like those lace gloves like she wore in that really fine cotton. And so and there's other patterns here too. So   Kelly 49:15 cool.   Marsha 49:16 Yeah, I don't know. Okay, well, we went we went down a rabbit hole on that. Okay.   Kelly 49:23 But you know, you can have a, you could have a nice pair of gloves for Easter. So lots of possibilities. Join us. There's a chat thread and there's a finished object thread. Quite a bit of chat going on about the projects that people are doing not very many finished objects yet but there are a few I noticed.   Marsha 49:42 So,   49:43 and then our Winter Weave Along, not much time left. I have hopes of getting at least something else started if not finished. But we'll see. The only reason I still have hope is because I have spring break. Coming the third week of March, so two weeks, two weeks from now I have spring break. Yay. So maybe I could do something during spring break in terms of the weaving, but otherwise, I'm almost, I'm almost sure that I don't I, I'm almost sure I won't get something finished. But I might get something else on the loom. Because it ends March 31. So another year of weaving coming to an end for us. But if you're in the Jane Stafford Guild, her year of weaving is just starting. So that's kind of fun.   Marsha 50:37 Okay, one ends and one begins so you get you get to truly a full year. Well, I guess it's been a full year.   Kelly 50:44 I haven't ever kept up with hers. And like woven the thing, the projects in the guild, at the time that everybody else, you know, at the time that the the videos come out? I wanted to do that this year, but I'm not sure. I don't know. This might not be the year teaching online. It's getting better. I have to I have to admit it is getting better. But well, you know. It's it's not my favorite thing.   Marsha 51:11 Well, we should not end the podcast on the same vein as it started. Listening to Kelly rant about stuff she doesn't like! Yes. So anyway, the winter weave along is, is ending March 31. So get your projects in, put them in the finished objects thread. Then we'll be doing a drawing and one of the things that we have as a prize is a class that was donated by Erika from Weavolution. So. And then the other thing that I just wanted to say, before we end is I wanted to thank our new patrons! We have three new patrons. Jane, Heddi, and Jan since the last time I mentioned new patrons. So if you'd like to be a patron, how you do that is you go to patreon.com/twoewes. And you'll see our... I guess it's a channel or a page. I don't know, our account. And then and you can you can become a patron and support the show. So really, thank you so much Jane and Heddi, and Jan for for contributing to the show. It allows us to provide, you know, the podcast hosting and prize mailing and all those kinds of things and something new, Marsha! Something really exciting that we're able to do because of the patrons. Transcripts. Oooh! Oh, yes.   Kelly 52:41 So we now have a transcript of our podcast. Having used the transcription service for my classes, I learned a little bit more about the company that's powering the transcriptions for our for work on our classes. It's otter.ai. And so I went to their website, and they have regular accounts for regular people. And not you know, not just education and and such. And so I found out a little bit more about it. And so we just when the when the podcast is done, you submit it, it creates a transcript. You have to edit it because it's not entirely... It's not entirely accurate. It doesn't always understand when Marsha and I talk over each other. So there is a little editing to do for that. But But now we have a transcript that is attached. It's in the show notes at the end. So we have our regular show notes posted on the blog. And then at the end of that show notes post is the transcript. Okay, I have to say it is almost as an nerving to read as my math. My teaching transcript. I don't know if you read if you had a chance to read?   Marsha 54:06 I didn't read it. And now actually as you were talking about all this I was sort of thinking to myself, I don't know that I want to read it because...Oh, here it is. Okay. Here. I'm sorry. I think this is what we say every every episode. Kelly: hi Marsha. Marsha: Hi, Kelly. Kelly: How's it going? Marsha: Pretty good. Kelly: Good.   Kelly 54:28 Yes. It doesn't... I have to say, yeah, it made me laugh to read how it sounds, but it makes it available to people that wouldn't be available to otherwise.   Marsha 54:41 So Kelly, we need to edit this. Because you say you know "good," and then I say "had pretty exciting weather here in Seattle. A little unusual for us that we had a huge snores" Oh! This is what I said "Excuse me, snore a huge snowstorm came through. [laughing} I did actually say that! Okay, [laughing]   Kelly 55:06 yeah.   Marsha 55:07 Okay, This is terrible. This is embarrassing. I'm gonna have to do a much better.   Kelly 55:14 So now remember when we talked about how I was like, Oh my god, how could I have been teaching this long and not make any sense?   Marsha 55:23 Yes. Well, what I'm just laughing about is is that it was not the episode where I'm trying to explain helical knitting. Yeah, and I'm waving my hands around in the air trying. Yeah, but so   Kelly 55:39 it's been an interesting process, we'll probably get better. The transcripts will probably get better as we go along. But, you know, I become more aware, it would never have occurred to me a year ago, two years ago, it would never have occurred to me that you would need a transcript for a podcast. My thinking would have been well, why would someone who can't hear even think to listen to a podcast? Right? And, and my, my eyes have been opened, you know, having to make my class accessible to my students. And then other things, you know, the conversations about racism and structural, structural racism. And all of those conversations have just kind of opened my eyes and made me think about things that, that I didn't think about before, I would not have thought about a reason for making a podcast, an audio experience, available to someone who couldn't hear.   Marsha 56:40 So I'm not.[laughing] I'm sorry, I am not laughing about what you're saying. Just so you know, I'm sort of chuckling because I'm listening to what you're saying. But I'm also kind of scanning the transcript. So I'm sorry, I am not laughing at all at what you're saying.   Kelly 56:52 What are you laughing about now?   Marsha 56:54 Okay, so um, so it was very pleasant to sit out there on a snowy day because you have heat but anyway, period. Then that night, it just started coming down and it snowed all day period. I mean, all Friday night, Friday morning, or excuse me, Saturday morning, all Saturday into Sunday. Just It never stops. And we have I mean, eight someplace about eight inches probably at my house. Snow, that's a lot of snow for us. We don't usually get that much. But of course then Sunday, late Sunday afternoon or evening. It just turned around. [laughing]   Kelly 57:36 Marsha, this is what we talk about.   Marsha 57:38 Oh my gosh. [laughing] And then it just became soup out there. You know? Kelly? We have to do a better job. This is terrible! So eye opening what sounds okay in normal conversation is not okay. The transcript it's unreadable. Pretty much. Oh, my gosh, it's too funny. [laughing] Well, anyway, I have work to do. On clarity,   Kelly 58:15 We both, we both do, I think, having having read through it last last time to do the editing. Yeah, we both do. So anyway, now we have transcripts. And I'm very happy that we're able to do that. And it's thanks to the contributions of our patrons. So thank you very much for contributing to the podcast.   Marsha 58:41 I'm still laughing I'm sorry. I will stop laughing.   Kelly 58:48 Okay, Marsha. [laughing] Are we done?   Marsha 58:54 This reminds me of those times over the course of our friendship where we'd have those laughing attacks.   Kelly 58:59 Yes.   Marsha 59:00 And have accidents. So I better get off the podcast. We better get off the phone before I have an accident.   Kelly 59:07 All right. Bye! [laughing]   Marsha 59:13 Okay, bye bye. [laughing]   Kelly 59:16 To subscribe to the podcast visit Two Ewes Fiber Adventures dot com.   Marsha 59:21 Join us on our adventures on Ravelry and Instagram. I am betterinmotion and Kelly is 1hundredprojects   59:29 until next time, we are the Two Ewes doing our part for a world fleece!  

We Built A Thing
084 - Storage Racks, Plasti-Dip for Clamps & Helical Heads

We Built A Thing

Play Episode Listen Later Feb 25, 2021 63:39


In this episode, Mark gets his furnace to limp through the rest of this cold season while he installs a bunch more lumber storage in the shop. Drew has to move his tools around to mill the longer walnut lumber for his upcoming project. Bruce has been laser cutting acrylic templates and shipping them all over the place. Plus, he finally finished the video and plans for the CNC table (that could also be an assembly table...download the free plans from the video link below) Become a patron of the show to receive awesome rewards! http://patreon.com/webuiltathing Help us grow our audience by sharing the show on Instagram and tagging @webuiltathing OUR TOP PATREON SUPPORTERS: -YouCanMakeThisToo-JK Canvas-Jennie and Davis-Tom's Woodwork-Chiseled Woodworking-Tim Morrill-Brent Jarvis  -Dad It Yourself DIY-Broken Lead Woodworks-Chris Powell-Christopher Simonton-Maddux Woodworks -Ray Jolliff -Firewood Designs -Ryder Clark -James Attaway Lumber racks mentioned in the show: https://amzn.to/2ZMexoc We Built A Thing T-shirts! We have two designs to choose from! (You can get one of these as a reward at certain levels of support) https://amzn.to/2GP04jf  https://amzn.to/2TUrCr2 Bruce's most recent video: https://youtu.be/GNKQwikXCQA Drew's most recent video: https://youtu.be/jcJe6NFoY_0 Mark's most recent video: https://youtu.be/KrEnLvOIi1I We are all makers, full-time dads and all have YouTube channels we are trying to grow and share information with others. Throughout this podcast, we talk about making things, making videos to share on YouTube, Instagram, Facebook, etc...and all of the life that happens in between.  CONNECT WITH US: WE BUILT A THING: www.instagram.com/webuiltathingWE BUILT A THING EMAIL: webuiltathing@gmail.com FISHER'S SHOP: www.instagram.com/fishersshop/ BRUDADDY: www.instagram.com/brudaddy/ GUNFLINT DESIGNS: www.instagram.com/gunflint_designs/ Music by: Jay Fisher (Thanks, Jay!)

Two Ewes Fiber Adventures
Ep 155: Extremities Knit or Crochet Along

Two Ewes Fiber Adventures

Play Episode Listen Later Feb 14, 2021 52:07


Lots of tangents and a new KAL/CAL inspired by some new patterns for your hands and feet generously donated by the designers as prizes. Full show notes with photos and links can be found in the podcast section of our shop website: TwoEwesFiberAdventures.com. Subscribe on Apple Podcasts or Subscribe on Android or Subscribe on Google Podcasts Marsha’s Projects I’m still working on the pair of socks for myself using Drops Fabel Print that I bought in San Luis Obispo. I’m back to working on the Walk Along by AnkeStrick and I’m using Little Fish Stitches fingering. I was having problems where I was alternating skeins at the beginning of row which was at the back of the sweater. A huge thank you to MyBlueGirl and Sarahjhill for suggesting Helical knitting. This solves the problem of the messy looking change. I started a spinning project with olive green merino roving I bought at the Whidbey Island Weavers meet up in April 2019. Combining it with another merino I ordered from Paradise Fibers in Spokane, Washington in a dark brown called Bitter Chocolate. Making a 3 ply with two green and one brown single. Kelly’s Projects  Finished!  I hemmed the Christmas Candy dishtowels and put them away!  I also finished With Friends Pullover using the pattern Rachel by Josée Paquin.  It still needs ends woven in and blocking. I’m really happy with how it turned out and I’m looking forward to wearing it.  The Persian Tile Blanket is coming along, but I didn’t work on it as much in the last two weeks. Instead I started a pair of socks for Robert. I’m using leftovers of Leading Men Fiber Arts Show Stopper, Independent Will colorway. I had 90 grams left after using it for argyle socks for my brother-in-law. Not sure I’ll have enough but I’m planning to use toes and heels of a different yarn. Extremities Knit/Crochet Along This KAL/CAL was inspired by the generous donation of these patterns: Abington Mitts, Jennifer Lassonde, Down Cellar Studio Coffee Socks Collection, Dotsdabbles Designs, Deborah   It starts now (February 2021) and will end on April 25, 2021. Knit anything for your extremities (hands, arms, legs, feet). Some examples include socks, leg warmers, mitts,  mittens, gloves, and wristlets. There will be a giveaway thread in the Ravelry Group for you to post your FOs.  Winter Weave Along You can join in with your weaving projects anytime until March 31. We will have prizes, including a class generously donated by Erica at Weavolution. Check out this great website for weavers with projects, discussion, classes, and lots of resources. The website has a handy Weaving Calculator that you can use for project planning.

Ham Talk Live!
Episode 240 - New Helical Antennas

Ham Talk Live!

Play Episode Listen Later Dec 18, 2020 47:53


John Portune, W6NBC is back to talk about his latest creation featured in QST - a helical copper tape and PVC antenna that can be used similar to a J-pole, but can also work on the HF bands.Be sure to CALL in with your questions and comments by calling 859-982-7373 live during the call-in segment of the show. You can also tweet your questions before or during the show to @HamTalkLive.w6nbc.comProgramming note: Ham Talk Live! will not be on the air Christmas Eve and New Year's Eve. Join us next time on January 7, 2021.

Jean & Mike Do The New York Times Crossword

Today's crossword was ALITTLE easier than yesterday's epic. Jean's favorite clue was 79A, Nickname for baseball great Ernie Banks, MRCUB, Mike's was a tie between 44A, Brand that comes out a head?, PEZ, and 78D, Helical bit, AUGER. Both Jean and Mike were surprised to learn the existence of 104A, Peninsula shared by Italy, Slovenia and Croatia, ISTRIA, and wondered if the author might've had a few AYS about 105D, Exclamations of regret, AYS, in lieu of OYS.We just hit 5000 downloads, so thank you, our loyal listeners,  for all your support!

The Ultimate Deck Podcast
Helical Screw Piles... 5 Reasons to Use Them and 3 Reasons to Not // Episode 99

The Ultimate Deck Podcast

Play Episode Listen Later Oct 10, 2020 59:44


Helical screw piles are one of the best innovations to ever happen for deck builder.  We are BIG fans of helical screw piles, and so here are 5 reasons why they are so amazing!  But not so fast, they aren't ALWAYS great, so we have 3 reasons why you might not like them too.   Find more The Ultimate Deck Shop: https://www.youtube.com/theultimatedeckshop https://instagram.com/theultimatedeckshop https://www.facebook.com/theultimatedeckshop https://www.tiktok.com/@theultimatedeckshop https://twitter.com/theultdeckshop

PaperPlayer biorxiv biophysics
Control of helical navigation by three-dimensional flagellar beating

PaperPlayer biorxiv biophysics

Play Episode Listen Later Sep 27, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.27.315606v1?rss=1 Authors: Cortese, D., Wan, K. Y. Abstract: Helical swimming is a ubiquitous strategy for motile cells to generate self-gradients for environmental sensing. The model biflagellate Chlamydomonas reinhardtii rotates at a constant 1 - 2 Hz as it swims, but the mechanism is unclear. Here, we show unequivocally that the rolling motion derives from a persistent, non-planar flagellar beat pattern. This is revealed by high-speed imaging and micromanipulation of live cells. We construct a fully-3D model to relate flagellar beating directly to the free-swimming trajectories. For realistic geometries, the model reproduces both the sense and magnitude of the axial rotation of live cells. We show that helical swimming requires further symmetry-breaking between the two flagella. These functional differences underlie all tactic responses, particularly phototaxis. We propose a control strategy by which cells steer towards or away from light by modulating the sign of biflagellar dominance. Copy rights belong to original authors. Visit the link for more info

PaperPlayer biorxiv biophysics
Mechanistic Studies of the Stabilization of Insulin Helical Structure by Coomassie Brilliant Blue

PaperPlayer biorxiv biophysics

Play Episode Listen Later Aug 27, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.26.267799v1?rss=1 Authors: Bhunia, A., Maiti, N. C. Abstract: Human insulin (HI) is an essential protein hormone and its biological activity mostly depends on folded and active conformation in the monomeric state. The present investigation established that Coomassie Brilliant Blue G-250 (CBBG), a small multicyclic hydroxyl compound can reversibly bind to the hormonal protein dimer and maintained most of alpha-helical folds crucial for biological function of the enzyme. The solution-state 1D NMR and isothermal calorimetric analysis showed a sub-micromolar binding affinity of the molecule to HI. 2D NOESY NMR established that the HI dimer undergoes residue level local conformational change upon binding to CBBG. The chemical shift perturbation and the NOE parameters of active protons of amino acid residues throughout the polypeptides further suggested that CBBG upon binding the protein stabilize alpha-helixes of both the A and B subunits of the hormonal protein. The changes in Gibbs free energy of the binding was of ~-11.1 kcal/mol and suggested a thermodynamically favourable process. The changes in enthalpy and entropy term were -57.2 kcal/mol and 46.1 kcal/mol, respectively. The negative changes in entropy and the NOE transfer effectiveness of several residues in the presence of CBBG molecules indicated that the binding was an enthalpy driven favourable equilibrium process. The NMR-based atomic resolution data and molecular docking studies confirmed that the CBBG binds to HI at the dimeric stage and prevents the availability of the crucial residue segments that partake directly in further oligomerization and subsequent fibrillation. Extended computational analysis based on chemical shift perturbation of protons of active residues further established receptor-ligand based pharmacophore model comprised of 5 hydrophobic and a hydrogen bond acceptor features that can anchor the residues at the A and B chains of HI and inhibit the partial unfolding and hydrophobic collapse to nucleate the fibrillation. Taken together, the results demonstrated that CBBG and their close analogues might be useful to develop a formulation that will maintain the active and functional form of the hormonal protein for a significantly longer time. Copy rights belong to original authors. Visit the link for more info

PaperPlayer biorxiv biophysics
Photocatalytic plant LPOR forms helical lattices that shape membranes for chlorophyll synthesis

PaperPlayer biorxiv biophysics

Play Episode Listen Later Aug 20, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.19.257774v1?rss=1 Authors: Nguyen, H. C., Melo, A. A., Kruk, J., Frost, A., Gabruk, M. Abstract: Chlorophyll (Chl) biosynthesis, crucial to life on Earth, is tightly regulated because its precursors are phototoxic. In flowering plants, the enzyme Light-dependent Protochlorophyllide OxidoReductase (LPOR) captures photons to catalyze the penultimate reaction: the reduction of a double-bond within protochlorophyllide (Pchlide) to generate chlorophyllide (Chlide). In darkness, LPOR oligomerizes to facilitate photon energy transfer and catalysis. However, the complete 3D structure of LPOR, the higher-order architecture of LPOR oligomers, and the implications of these self-assembled states for catalysis, including how LPOR positions Pchlide and the cofactor NADPH, remain unknown. Here we report the atomic structure of LPOR assemblies by electron cryo-microscopy (cryoEM). LPOR polymerizes with its substrates into helical filaments around constricted lipid bilayer tubes. Portions of LPOR and Pchlide insert into the outer membrane leaflet, targeting the product, Chlide, to the membrane for the final reaction site of chlorophyll biosynthesis. In addition to its crucial photocatalytic role, we show that in darkness LPOR filaments directly shape membranes into high-curvature tubules with the spectral properties of the prolammelar body, whose light-triggered disassembly provides lipids for thylakoid assembly. Our structure of the catalytic site, moreover, challenges previously proposed reaction mechanisms. Together, our results reveal a new and unexpected synergy between photosynthetic membrane biogenesis and chlorophyll synthesis in plants orchestrated by LPOR. Copy rights belong to original authors. Visit the link for more info

PaperPlayer biorxiv biophysics
Mechanism of negative membrane curvature generation by the IRSP53 I-BAR domain

PaperPlayer biorxiv biophysics

Play Episode Listen Later Aug 19, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.19.256925v1?rss=1 Authors: Nepal, B., Sepehri, A., Lazaridis, T. Abstract: The membrane sculpting ability of BAR domains has been attributed to the intrinsic curvature of their banana-shaped dimeric structure. However, there is often a mismatch between this intrinsic curvature and the diameter of the membrane tubules generated. For example, I-BAR domains are almost flat but generate much higher membrane curvature. Furthermore, F-BAR and I-BAR domains are quite similar, but the former generates positive curvature and the latter negative curvature. Here, we use implicit-solvent computer modeling to show that the membrane bending of the IRSP53 I-BAR domain is dictated by its oligomeric structure, whose curvature is completely unrelated to the intrinsic curvature of the dimer. We find that I-BAR dimers undergo lateral and end-to-end interactions to form higher oligomers. The lateral interactions, which can occur with varying register, are stronger and give a curved shape that has the membrane binding interface on its convex surface. Two other I-BARs (MIM and I-BARa) gave similar results, whereas a flat F-BAR sheet curved to make its membrane binding interface concave, consistent with positive membrane curvature generation. Individual dimers orient parallel to the tube axis when the tube radius is small, whereas perpendicular orientation is preferred for larger diameter tubes. This orientational preference exists even in the higher oligomeric form. Helical spirals on tube interiors are stable at a density comparable to experimental measurements. The sorting ratio computed from our membrane binding energies is also consistent with experimental measurements. Copy rights belong to original authors. Visit the link for more info

PaperPlayer biorxiv biochemistry
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks

PaperPlayer biorxiv biochemistry

Play Episode Listen Later Jul 28, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.27.221333v1?rss=1 Authors: Hsia, Y., Mout, R., Sheffler, W., Edman, N. I., Vulovic, I., Park, Y.-J., Redler, R. L., Bick, M. J., Bera, A. K., Courbet, A., Kang, A., Brunette, T., Nattermann, U., Tsai, E., Saleem, A., Chow, C. M., Ekiert, D. C., Bhabha, G., Veesler, D., Baker, D. Abstract: A goal of de novo protein design is to develop a systematic and robust approach to generating complex nanomaterials from stable building blocks. Due to their structural regularity and simplicity, a wide range of monomeric repeat proteins and oligomeric helical bundle structures have been designed and characterized. Here we describe a stepwise hierarchical approach to building up multi-component symmetric protein assemblies using these structures. We first connect designed helical repeat proteins (DHRs) to designed helical bundle proteins (HBs) to generate a large library of heterodimeric and homooligomeric building blocks; the latter have cyclic symmetries ranging from C2 to C6. All of the building blocks have repeat proteins with accessible termini, which we take advantage of in a second round of architecture guided rigid helical fusion (WORMS) to generate larger symmetric assemblies including C3 and C5 cyclic and D2 dihedral rings, a tetrahedral cage, and a 120 subunit icosahedral cage. Characterization of the structures by small angle x-ray scattering, x-ray crystallography, and cryo-electron microscopy demonstrates that the hierarchical design approach can accurately and robustly generate a wide range of macromolecular assemblies; with a diameter of 43nm, the icosahedral nanocage is the largest structurally validated designed cage to date. The computational methods and building block sets described here provide a very general route to new de novo designed symmetric protein nanomaterials. Copy rights belong to original authors. Visit the link for more info

Another Woodshop Podcast
Episode 2: Helical Head Dado Stack

Another Woodshop Podcast

Play Episode Listen Later Mar 26, 2020 65:42


Hello and welcome to episode 2! This week we compare Woodworkers & Influencers, answer listener questions and bicker like children! We also go over which tools we'd want with us on a desert island! You can leave us a voice message at (754) 225-5297 or you can record your question or comment on your phones voice memo app and email it to anotherwoodshoppodcast@gmail.comYou can follow us all and the podcast on Instagram and YouTube!Podcast on Instagramhttps://www.instagram.com/anotherwoodshoppodcast/Dan on Instagramhttps://www.instagram.com/danieldunlap.woodworks/Mike on Instagramhttps://www.instagram.com/coffeycustombuilds/Pete in Instagramhttps://www.instagram.com/ptreesworkshop/Mike on YouTubehttps://www.youtube.com/coffeycustombuildsDan on YouTubehttps://www.youtube.com/danieldunlapSupport the show (http://www.patreon.com/anotherwoodshoppodcast)

Woodshop Life Podcast
Episode 36 - Veneer Glue, Capacity or Helical Cutter, Cheap Bits & MUCH More!

Woodshop Life Podcast

Play Episode Listen Later Jan 2, 2020 50:45


Support us on Patreon: https://www.patreon.com/woodshoplife   Guys Questions 1) Can you speak a little in general about expansion and contraction of wood with some basic Do Not vs. Do when it comes to glueing and allowing wood movement?  Thanks in advance, I am learning a ton! April 2) Hey Guys, I’ve got a question for the podcast that I’ve never heard anyone address. Is it worth it to invest in high-dollar drill bits?  As a hobbiest on a tight budget, I generally get new bits at the box store, but sometimes I can look at them while they are spinning, and tell that they are not spinning straight. They seem to do the job, but I always wondered if having better bits (or possibly a better drill, I guess) is worth the money? Thanks, and love the great show format. Sincerely, Scott A. Jackson, TN   Sean's Questions 1) Hello, I would like your opinion what would be the better upgrade option around the 300-400 dollar range. I currently have a 60's era Delta 6" jointer with a 1.5HP motor and am debating on whether I should upgrade to a carbide helical cutter head or should I upgrade my capacity with a used 8" jointer which I can usually find around here for about a hundred more. Thanks for the podcast, it's going great! - Travis 2) Love your podcast. Your show is amazing and I love all three of your social stuff. Guy, your YouTube page is amazingly helpful for me. I'm a hobbiest woodworker who sells pieces based upon commission only. I've been building out my shop via commissioned projects over the past 4 years. I started with all HD Ryobi stationary tools to learn on and now am upgrading to more professional tools. Here's what I have so far: Laguna F2 hybrid table saw, just got it and love it, it took some mods for dust collection but it's awesome. Wen drill press. Craftsman used lathe(got it for $100 from a neighbor) basically brand new. Rigid miter saw station. Porter and cable router on a homemade table. Dust collection system with a shop vac and dust deputy. 10 inch wen band saw. My question is what do I get next? Drum sander? Or planer/jointer combo? My budget is around $1200 and space is an issue. I work in a 1 car garage. I do have everything on wheels except the table saw. Hope I didn't ramble. Keep up the great work. Brad  Huy's Questions 1) What glue do you use for veneering? Are there any circumstances when you would change the glue your using, such as curved panels, color of veneer, or purchased vs shop sawn veneer?Douglas 2) I don’t think I have heard y’all talk about these before so here you go. Woodpecker tools. What do y’all think of them?  Are there better or cheaper tools out there that will work as good? I have a few Woodpecker tools and I really like them and find them very useful but just looking for other options out there. I also have bought a few of their one time tools and have been very pleased with them. Keep up the great work guys! - Troy   Thanks to Maverick Abrasives for sponsoring this episode!

Science Faction Podcast
Episode 270: Blue Light Special

Science Faction Podcast

Play Episode Listen Later Oct 23, 2019 74:43


This Episode Contains: It’s been a week, says Steven. Steven tells us about his life and Devon tells us about how much his mother-in-law hated Joker. Get Physical: NASA engineer's 'helical engine' may violate the laws of physics. Designed by David Burns at NASA’s Marshall Space Flight Center in Alabama, the “helical engine” exploits mass-altering effects known to occur at near-light speed. However, would also need to be big – some 200 meters long and 12 meters in diameter – and powerful, requiring 165 megawatts of power to generate just 1 newton of thrust. https://www.newscientist.com/article/2218685-nasa-engineers-helical-engine-may-violate-the-laws-of-physics/ Biological Imperative: Daily exposure to blue light may accelerate aging, even if it doesn't reach your eyes. Prolonged exposure to blue light, such as that which emanates from your phone, computer and household fixtures, could be affecting your longevity, even if it's not shining in your eyes. New research suggests that the blue wavelengths produced by light-emitting diodes damage cells in the brain as well as retinas, according to a new study in a model organism. https://www.sciencedaily.com/releases/2019/10/191017101253.htm Sci-Fi: Star Wars Jedi: Fallen Order has gotten good buzz. Steven finished Iron Gold (Red Rising) by Pierce Brown and is now reading the next book: Dark Age. Devon tells us about the podcasts he is listening to. We then play some of Devon’s new music and he discusses what he might want to do with music in the future. Steven still hasn’t seen season 2 of Star Trek: Discovery. Devon liked the new Picard trailer. We then guess actors ages. We also talk about Love, Death and Robots, and Bojack Horseman.  

Coffee Break: Señal y Ruido
Ep237: Insight, Higgs y Helical Engine; Carne Roja; Aharonov-Bohm e Invariancia Gauge; Radiotelescopio Arecibo

Coffee Break: Señal y Ruido

Play Episode Listen Later Oct 17, 2019 153:39


La tertulia semanal en la que repasamos las últimas noticias de la actualidad científica. En el episodio de hoy: Breves: Insight en Marte (min 5:00), Bosón de Higgs (8:00) y Helical engine (18:30); Carne roja y recomendaciones de salud (43:20); Efecto Aharonov-Bohm y la inariancia gauge en cuántica (1:20:40); Entrevista Ing. Francisco Córdova, director del Observatorio de Arecibo (1:54:30). En la foto, de arriba a abajo y de izquierda a derecha: Sara Robisco, Francis Villatoro, Carlos Westendorp, Héctor Socas. Todos los comentarios vertidos durante la tertulia representan únicamente la opinión de quien los hace… y a veces ni eso. CB:SyR es una colaboración del Museo de la Ciencia y el Cosmos de Tenerife con el Área de Investigación y la UC3 del Instituto de Astrofísica de Canarias.

Coffee Break: Señal y Ruido
Ep237: Insight, Higgs y Helical Engine; Carne Roja; Aharonov-Bohm e Invariancia Gauge; Radiotelescopio Arecibo

Coffee Break: Señal y Ruido

Play Episode Listen Later Oct 17, 2019 153:39


La tertulia semanal en la que repasamos las últimas noticias de la actualidad científica. En el episodio de hoy: Breves: Insight en Marte (min 5:00), Bosón de Higgs (8:00) y Helical engine (18:30); Carne roja y recomendaciones de salud (43:20); Efecto Aharonov-Bohm y la inariancia gauge en cuántica (1:20:40); Entrevista Ing. Francisco Córdova, director del Observatorio de Arecibo (1:54:30). En la foto, de arriba a abajo y de izquierda a derecha: Sara Robisco, Francis Villatoro, Carlos Westendorp, Héctor Socas. Todos los comentarios vertidos durante la tertulia representan únicamente la opinión de quien los hace… y a veces ni eso. CB:SyR es una colaboración del Museo de la Ciencia y el Cosmos de Tenerife con el Área de Investigación y la UC3 del Instituto de Astrofísica de Canarias.

Discover Lafayette
Kohlie Frantzen – Advocate for Sustainable Hydroponic Farming

Discover Lafayette

Play Episode Listen Later Aug 23, 2019 54:58


Imagine farming without needing hundreds of acres or having to get your hands dirty in the soil. How about saving up to 90% of the water needed in conventional agriculture to successfully produce a high-yield, high-margin crop, and possibly serving as a catalyst for our next generation to explore a career in sustainable farming? Our guest on this episode of Discover Lafayette, Kohlie Frantzen, founder and managing partner of Helical Outposts, discusses all of this, and much more. Kohlie Frantzen is a certified hydroponicist engaged in hydroponic farming, which is done in a controlled environment protected from the elements and doesn’t need soil to grow produce. You can grow the equivalent of 3 acres of crops in a space as small as 3000 square feet.  Picture a large storage container with a big greenhouse (pod) next to it that can fit in a small postage stamp of real estate. Kohlie Frantzen and his partner at Helical Outposts, Dylan RatiganStudents at John Paul the Great Academy engaged in hydroponic farming.Helical Outpost showing solar panels The son of the late Dan Frantzen, a co-founder of Stone Energy, Kohlie is an attorney who grew up believing he could chase his dreams just as successfully as his dad did as a wildcatter in the oil and gas industry. Kohlie has transitioned into the agriculture world and is now a proponent of the many benefits of hydroponic farming. Kohlie co-founded Helical Holding with Dylan Ratigan, a former MSNBC host. He was initially drawn to the concept of hydroponic farming as a way to assist returning veterans in finding sustainable employment, or as he stated, "to give them a vocational path rather than a benefits path. However, his wife's family are farmers in Crowley and he was extremely skeptical of the claims made about hydroponic farming. In order to understand the concept of farming without soil, he attended a six-week course in Southern California which taught him a lot about the technical end of hydroponics, but not much in the way of practical knowledge as to how to sustain the practice as a successful business model. Kohlie decided to use his oil and gas background and apply it to hydroponics. Utilizing standard operating practices in a similar manner to the oil and gas mentality of "quickly setting up, do what you have to do, and then pack up and move on to the next job," hydroponics gives farmers great flexibility in where their "farm" is set up and keeps costs down as compared to conventional farming which demands vast acreage and resources. The advantages of hydroponic farming are many. First of all, the weather is not an issue as the pod protects the plantings from the elements and can be moved when threats such as hurricanes or floods are on the horizon. The plants grow faster as they receive nutrients 24 hours a day, 7 days a week through recirculated water. Vegetables grow about 25 percent faster and produce 30 percent more in hydroponic systems Hydroponic farming systems use 90 percent less water, 90 percent less land, and produce the equivalent of as much as 3 acres of organic farm soil in as little as 5,000 square feet. It also has satellite internet access and a water filtration system. Each pod is a power station, communication hub, and a water purifier all in one. Interestingly, hydroponics has actually been around for thousands of years. Many of us are familiar with the Hanging Gardens of Babylon, one of the seven wonders of the world. Built along the Euphrates River around 600 B. C., the gardens were watered using a chain pull system. Later in the 10th and 11th Centuries, the Aztecs utilized hydroponics on Lake Tenochtitlan, and similar floating gardens are in use today in Myanmar. Hydroponic farming has great potential to provide healthy produce to food deserts in neighborhoods without easy access to food, especially fresh produce. One of Helical’s earliest clients was St. Joseph’s Diner in Lafayette,

Within Tolerance
Within Tolerance Episode 7 - Preventing Headbanging

Within Tolerance

Play Episode Listen Later Aug 15, 2019 49:50


Welcome to the Within Tolerance Podcast! This podcast is where Payton Dean (BrickTactical) and Dylan Jackson (Proteum Machining) talk shop! Today we talk about how Helical impressed Dylan on his large stainless steel part that he just finished up! While Dylan stays into 1 am in the morning to finish up some jobs, Payton's HAAS is hard at work cranking out more injection molds for BrickTactical. We also talk about how to get through stressful situations in the shop so you can prevent scraping more parts.

Business of Machining
Business of Machining - Episode 130

Business of Machining

Play Episode Listen Later Aug 8, 2019 39:00


Portland, Oregon. Autodesk Fusion 360 Academy Day 2. Sans the glitz, glam, and exuberance of Autodesk University Las Vegas, the close-nit vibe and Fusion focused course material makes for an amazing time. Saunders shares an AWESOME Fusion 360 hack from Rob Lockwood's 5-Axis Fixturing Course. IT'S A SMALL WORLD During the event, Saunders has dinner with Don Grant from Helical/HarveyTool, the same person Grimsmo met at Autodesk Toronto in July. Turns out, Don had a sweet solution for Grimsmo's 3/32 problem! TOOL MORTALITY...or IMMORTALITY (may be an exaggeration but...just go with it) During critical knife handle milling, 3/32 4-flute endmills were dying within 1 pallet, which means having to re-work each pallet (PAINFUL) BUT---the good news is the Helical 5-flute endmill coated for titanium has lasted through 17 PALLETS AND IS STILL GOING STRONG! NOT COOL, BRUH. AC gets repaired only to break down again two days later. Although the Nak LOVES the heat and is churning out uber-consistent parts...the lapping machine begs to differ! How's the TORNOS? An expensive coding mistake serves as reminder to quadruple check code AND make sure the post is smooth, refined, and operating without requiring manual manipulation. Home Sweet Home Grimsmo and FAM are moving into their first home! SHADOW PEOPLE The desire to see a day in the life of other shop owners has remained strong for Saunders, especially if he could do it in stealth mode. Everyone tends to change behavior slightly in the presence of company or a camera. Corncob, Triangles, & Toblerones The new tumbler that emerged from a trade deal has dividers. Erik tosses his SAGA into the corncob section to see how it holds up.

Outdoor Podcast Channel
Up North Journal - Arrow Tuning, Western Hunting Workshop

Outdoor Podcast Channel

Play Episode Listen Later Jul 1, 2019 87:54


Mike and Dan talk with Chris Schnur of Beyond The Ears about arrow tuning and custom tuned arrows. Mike had Chris set up a new dozen for his new PSE Shootdown Forgiveness in an arrow Arrow stiffness affects Front weight and how it affects the arrow Speed vs Kinetic Energy The bow vs the arrow, which part should you put the most thought into? Putting more thought process into the arrow choice Aluminum shafts Easton Gamegetter XX75 Carbon shafts Stainless steel cores Parallel shafts Tapered shafts What is spine? How an arrow is manufactured affects spine deviance How broadhead air foil affects fletchings Trend now is going back to 3 or 4 inch vanes Blazer vanes developed for whisker biscuits Helical vs offset vanes Arrow components are often overlooked New technology Grouping 20 yards in a 8 inch pie plate Why custom vs boxed arrows Crossbow bolts Western Hunting Clinics How they got started at the shop What type of gear are they offering Workshops that teach them the gear they should consider Helps to prepare them for the extreme conditions they will endure Western hunts vs Mid-west hunts The elk calling academy Mike drew a Michigan Elk Tag! The Hunt, Hike, Train Podcast

Up North Journal Podcast
Episode 524, Arrow Tuning, Western Hunting Workshop

Up North Journal Podcast

Play Episode Listen Later Jun 30, 2019 87:54


Mike and Dan talk with Chris Schnur of Beyond The Ears about arrow tuning and custom tuned arrows. Mike had Chris set up a new dozen for his new PSE Shootdown Forgiveness in an arrow Arrow stiffness affects Front weight and how it affects the arrow Speed vs Kinetic Energy The bow vs the arrow, which part should you put the most thought into? Putting more thought process into the arrow choice Aluminum shafts Easton Gamegetter XX75 Carbon shafts Stainless steel cores Parallel shafts Tapered shafts What is spine? How an arrow is manufactured affects spine deviance How broadhead air foil affects fletchings Trend now is going back to 3 or 4 inch vanes Blazer vanes developed for whisker biscuits Helical vs offset vanes Arrow components are often overlooked New technology Grouping 20 yards in a 8 inch pie plate Why custom vs boxed arrows Crossbow bolts Western Hunting Clinics How they got started at the shop What type of gear are they offering Workshops that teach them the gear they should consider Helps to prepare them for the extreme conditions they will endure Western hunts vs Mid-west hunts The elk calling academy Mike drew a Michigan Elk Tag! The Hunt, Hike, Train Podcast  

EG Property Podcasts
Future of Real Estate: 146 bedrooms for young people at risk of homelessness

EG Property Podcasts

Play Episode Listen Later May 23, 2019 24:52


LandAid House opens in Autumn 2019, providing 146 bedrooms for young people at risk of becoming homeless. It’s been made possible by a £1m donation from Mike Slade, president of the charity and the outgoing chairman of Helical. He explains to Damian Wild why he has made the donation and what he hopes it will deliver for the future.

Propertyshe Podcast
Episode 4: Mike Slade

Propertyshe Podcast

Play Episode Listen Later Jan 10, 2019 28:53


Michael Slade FRICS, is Chairman of Helical plc, a UK-listed property development and investment company, one of the best performing quoted property stocks in the UK.

FUTURE FOSSILS
"Future Fossils 101" with Michelle Shevin & Michaelangelo

FUTURE FOSSILS

Play Episode Listen Later Dec 11, 2018 90:27


This week's guests are two of the most limber and insightful minds I know, futurist Michelle Shevin and actor-artist "The Ungoogleable" Michaelangelo. Since this is episode one of a whole new hundred episodes – and since I'm a sucker for ceremony and round numbers – this week we're taking a whirlwind tour of this show's recurring themes: how life, mind, culture, psychology, art, and science all change in the Internet Age, and how to live the best lives that we can amidst these transformations...Support the show for exclusive episodes, music, a book club, and more:patreon.com/michaelgarfieldMichelle Shevinmedium.com/@micheboxMichaelangelovoidandimagination.comWe Discuss:• Kronos & Kairos, revisited• Re: JF Martel – Episodes 18 & 71 • The information science of innovation and why Terence McKenna’s Timewave Zero may not be TOTAL hogwash• Book: Geoff West - Scale• Re: “An Oral History of the End of ‘Reality’” – Episode 91 • IS our time unique at all?• WJT Mitchell paraphrase: “We’re all constantly feeling as though everything is about to happen, or perhaps it already has and we just haven’t noticed it”• #presentshock• Did we miss the singularity?• Trapped in the present• MA: “chronopractic adjustments” of pulling your past and future into alignment• MA: “I feel like all expression is a form of deception…I try to look to the deception closest to the truth.”• Plato: “Writing is a step backward from Truth.”• Biological evolution as machine learning and the domestication of humans by technology• MA: “I took a hit of GPS / got lost within the endlessness / gave up the compass in my chest / and oriented to the West”• Michaelangelo – Episode 37 • Evolution’s bias toward paedomorphy / neoteny• MS: “What happens when DNA becomes the substrate for all this information?”• Storing data in the organic cloud• The zone of proximal evolution and how “We can’t invent what we don’t have the parts lying around for”• Every new technology is a remix• David Krakauer – Episode 75 • Dennis McKenna - Episode 88 • Toxoplasmosis mind control and how nobody actually things if “my brain made me do it”• MS: “If we are midwives to new myths, then part of the project is to litter the landscape with the right raw material, so that in the future, the right raw material is just lying around for people to pick up and build the tools with.”• MA: “meme-ifying” (vs. “mummifying”)• Book: Sam Harris – Free Will• Film: Upstream Color• Film: Primer• Book: Peter Watts – Blindsight• Book: Peter Watts – Echopraxia• Re: The Teafaerie – Episode 100 • Re: Erik Davis – Episode 99 • Re: Doug Rushkoff – Episode 67 • Weird Studies Podcast is amazing, their Episode 32 on Eyes Wide Shut• MG: “At the dusk of civilization, our eyes are adjusting to the darkness.”• The digital dark age• Book: Stewart Brand – The Clock of the Long Now• Richard Doyle on Philip K. Dick and the evolutionary arms race of cameras and blind spots leading inexorably toward paranoia and then beyond into metanoia (see also, “The Evolution of Surveillance Part 3: Living in the Belly of the Beast”)• An entropy-driven metabolic arms race inevitab fractal Argus, coated in eyes• When it comes to living through a Dark Age, MA suggests, “I think it comes down to learning how to glow in the dark. The agents of deception are our greatest teachers, in that sense.”• MA: “Increased surveillance creates more performative personalities.”• Re: Mitch Mignano – Episodes 57 & 98 • Elon Musk on Joe Rogan (of course that guy believes in simulation theory)• Song: Yeasayer’s “Under The Glass of the Microscope”• Linear, Circular, Helical time• MS: “Planning often disguises itself as prediction”• What is causation, anyway?• Possibility as a fractal branching lightning bolt from potential to actual• MA: “Scrye-ogenic Future” in a crystalline model of time• MA: synchronicities vs. “synchroniceties”• Book: Julian Jaynes – The Bicameral Mind• Daniel Dennett’s “software archeology”• The origins of divination• Morsels of bicamerality reinstated by our digital ecology, with someone’s agenda in it• MS: “The arrogance is in thinking that it was only ever us.”• The Neurological Explanation for Imaginary Friends• The Microbiological Explanation for “Self-Transforming Machine Elves”• Swing Low, Eukaryote, coming for to carry me home• David Pearce – “The Antispeciesist Manifesto”• Are Laboratory Burgers Vegan?• Empathy is a human (but not uniquely human) super power• Rebranding the human species (eg, “Dog Friends,” “Cat Friends”)• Book: Alejandro Jodorowsky - Where The Bird Sings Best• Expertise is knowing the right search terms• DNA as a language; microbial ecology as a language• Introspection as an escape hatch from history and “profane time”• And more... See acast.com/privacy for privacy and opt-out information.

Business of Machining
Business of Machining - Episode 88

Business of Machining

Play Episode Listen Later Oct 11, 2018 42:03


:: Solving a toolpath mystery :: :: The John Saunders Turkey Machine :: :: Don't judge a fish by how it climbs trees :: DEFINING BUSINESS OBJECTIVES Saunders asks himself, "What the heck ARE we?" Does having multiple areas of specialty dilute the business? After some revelatory conversations, he's "zeroing" in on what it means to be SMW. "Daddy, I'm trying to find John Saunders Turkey Machine Shop." While enjoying the Canadian Thanksgiving festivities, Grimsmo's daughter, Claire, is on the hunt for a hilarious and totally under-rated video. Click The Image to Watch! MACHINE SHOP LINGUISTICS Often, words lose their meaning and need updated to accurately reflect our ever-changing world. By changing the suffix, the word "Marketing" gets new life. TOOLPATH MYSTERY SOLVED! The gradual arc on a GK knife handle goes from 1 line of G-code to 50, leaving behind noticeable facets that the guys have to buff out. Luckily, in this digital age, we can turn to the machining community to ask for help! Thanks to @laurenswijnschenk, the proverbial thorn in Grimsmo's side is gone. Check out his Instagram HERE! BUST OUT THE FUSION 360 First, pull over and open your laptop! Have you ever used the "View Toolpath" feature in Fusion? If you haven't, you aren't alone! IMTS 2018 - GET YOUR FIX The NYC CNC full length IMTS video hasn't been published yet but here are some shorter IMTS videos to tie you over! Grimsmo Knives IMTS 2018 Day 1 - Becoming Swissish Grimsmo Knives IMTS 2018 Day 2 - Small Booths IMTS 2018 Top 10 CNC Machines GRIMSMO KNIVES is HIRING Their "We're Hiring" video has been released to the interwebs but in order to be seriously considered, you MUST make a short video about yourself! A deep conversation ensues about the art of hiring employees that you don't want to miss! Click the Image to Watch! THERE MUST BE A FULL MOON Saunders is back in NYC, looking at a Mori Seiki SL-1A with FANUC control...but will the forklift have enough capacity to handle the instruction manuals? Finally Got Some Green Tops! Grimsmo gears up to try out Helical tools for the first time.

Ambient Soundbath Podcast
Ambient Soundbath Podcast #70 – Helical Drone

Ambient Soundbath Podcast

Play Episode Listen Later Jun 15, 2018


https://ia601303.us.archive.org/26/items/AmbientSoundbathPodcast/asb70.mp3   Ambient Soundbath #70 is another original work in the vein of Parallax Drone; a piece inspired by Philip Glass’ Early Works where I’ve experimented with some compositional devices called parallel and contrary motion that he worked with on that recording… You can hear it in the criss-crossing of the sounds as they move…Read more Ambient Soundbath Podcast #70 – Helical Drone

Dom B Podcast
Poison Marijuana, Stan Lee, Billy Mitchell, Helical Orbit – Dom B Podcast 42

Dom B Podcast

Play Episode Listen Later Apr 12, 2018 42:44


3 people in Illinois have died due to rat poison found in a synthetic blend of marijuana. This type of marijuana can be purchased at tobacco shops throughout a few states. Marijuana is still illegal at a federal level. However, we seem to be coming around with the legalization of marijuana.   Stan Lee was tweeted at by Kevin Smith. Stan Lee has been having some financial issues recently and people are pouring out the hearts to Stan Lee in solidarity. Stan Lee has denied some of the allegations but apparent close friends have reinforced the allegations of Stan Lee’s new “friends”. I truly hope Stan Lee is helped and can move past this storm if these allegations are true. Stan Lee is the GOAT!   Billy Mitchell… I’m not a fan and I explain why I do not like Billy Mitchell. Okay, I don’t explain why I hate Billy Mitchell but I do talk about him… and I do dislike Bill Mitchel. Let Billy Mitchell be my first public beef!   Have you heard of the Helical Orbit for our solar system? If not, I chat about the Helical Orbit and what it should mean to us. We live in a wonderful universe full of mysteries. Don’t let the Helical orbit model be one of those mysteries and watch this video for more explanation!   Helical Orbit Video https://www.youtube.com/watch?v=mvgaxQGPg7I  For more of my work please go to iTunes - https://itunes.apple.com/us/podcast/dom-b-podcast/id1313384769?mt=2 Dom B Website - http://www.dombphotography.com/ Dom B Instagram - @dombphotography Dom B Twitter - @dombpodcast Dom B Facebook (Business) - https://www.facebook.com/Dom-B-Photography-484353875094683/?ref=bookmarks Dom B Facebook Personal - https://www.facebook.com/profile.php?id=100010289703861  

QSO Today - The oral histories of amateur radio

Ron Gang, 4X1MK, had his early amateur radio beginnings in Canada, and later immigrated, as part of a group, to Israel in the 1970s where his amateur radio license, skills, and equipment were highly appreciated.  Always an active amateur radio operator, 4X1MK is willing to try every operating mode. Ron shares his amateur radio story and his perspective of amateur radio in Israel, past and present.

The Options Insider Radio Network
Options Insider Radio Interviews: Talking Taxes, Sustainability and Options with Dylan Ratigan

The Options Insider Radio Network

Play Episode Listen Later May 1, 2017 49:49


In this episode, Mark is joined by Dylan Ratigan. You may be familiar with Dylan from: Being Chief Skeptic at Tastytrade Bloomberg News where he is the global managing editor CNBC where he created many programs you're probably familiar with, including Fast Money MSNBC where he hosted the Dylan Rattigan Show (MSNBC's highest-rated program outside of prime time from 2009 - 2012) Co-founder of Helical Holdings Political commentary work with the Young Turks His book, Greedy Bastards: How We Can Stop Corporate Communists, Banksters, and Other Vampires from Sucking America Dry They discuss: Covering the 2008 financial crisis in real-time The role in financial media in the lead-up and aftermath of the financial crisis Who is responsible for the financial crisis? Resigning from Fast Money and going to MSNBC President Obama's missed opportunity His book, Greedy Bastards: How We Can Stop Corporate Communists, Banksters, and Other Vampires from Sucking America Dry Will he write another book? His thoughts on the Trump administration's tax policy What would he tax instead of income? Are we heading toward an American oligarchy? How does he feel about transaction taxes? What is Helical Holdings, and how did he become involved? How his travel for Helical has changed his worldview How can people get involved? (Visit the website) His role with Tastytrade Is he an options guy?

Options Insider Radio Interviews
Options Insider Radio Interviews: Talking Taxes, Sustainability and Options with Dylan Ratigan

Options Insider Radio Interviews

Play Episode Listen Later May 1, 2017 49:49


In this episode, Mark is joined by Dylan Ratigan. You may be familiar with Dylan from: Being Chief Skeptic at Tastytrade Bloomberg News where he is the global managing editor CNBC where he created many programs you're probably familiar with, including Fast Money MSNBC where he hosted the Dylan Rattigan Show (MSNBC's highest-rated program outside of prime time from 2009 - 2012) Co-founder of Helical Holdings Political commentary work with the Young Turks His book, Greedy Bastards: How We Can Stop Corporate Communists, Banksters, and Other Vampires from Sucking America Dry They discuss: Covering the 2008 financial crisis in real-time The role in financial media in the lead-up and aftermath of the financial crisis Who is responsible for the financial crisis? Resigning from Fast Money and going to MSNBC President Obama's missed opportunity His book, Greedy Bastards: How We Can Stop Corporate Communists, Banksters, and Other Vampires from Sucking America Dry Will he write another book? His thoughts on the Trump administration's tax policy What would he tax instead of income? Are we heading toward an American oligarchy? How does he feel about transaction taxes? What is Helical Holdings, and how did he become involved? How his travel for Helical has changed his worldview How can people get involved? (Visit the website) His role with Tastytrade Is he an options guy?

Decipher SciFi : the show about how and why
Passengers: helical ship designs, the real Arcturus star, and ethics w/ Adrian Falcone

Decipher SciFi : the show about how and why

Play Episode Listen Later Jan 10, 2017 48:52


Ship design Segmented helix. Simulated/artificial gravity. Fusion reactors and constant acceleration. 0.5c after 30 years. Arcturus A red dwarf, 37 lightyears away from earth. Could the ship have made is to that point with the time and speed given? (no) This is the meat right here. Meaningless slingshots. Red Dwarves. Physics! Stasis Generation ships vs stasis pods. Stasis as a resource-saving measure. IRL research in “stasis” and muscle-mass conservation. Acceptable levels of brain deterioration. “Minor” brain damage. Anti-collision measures Kinda like magic. Atomizing rocks in space at 0.5c. Gravity and the ceasing thereof How simulated gravity works on a giant spinning torus (or, in this case, a segmented helix). How it ceases, and the physics necessary in order to create the effect seen in the film. Swimming out of floating water. Seveneves: iTunesAmazon "How did the Avalon (seemingly) get to Arcturus so quickly if they are only traveling at .5 of lightspeed?": Scifi & Fantasy Stack Exchange Support the show!

This Week in Virology
TWiV 346: A double helical career

This Week in Virology

Play Episode Listen Later Jul 19, 2015 61:03


Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guest: Joan Steitz This episode was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation. Links for this episode ASV annual meeting, Western University Steitz Laboratory at Yale University Steitz Laboratory on Twitter Panoramic photo of ASV TWiV by Matt Evans Photos of ASV2015 (Facebook) Video of this episode - view at YouTube Weekly Science Picks Kathy - Charity HallRich - Ribosome binding sites of phage R17 mRNAVincent - Pluto flyby Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Fakultät für Physik - Digitale Hochschulschriften der LMU - Teil 05/05
Cosmic-ray propagation in simulations of cross-helical plasma turbulence

Fakultät für Physik - Digitale Hochschulschriften der LMU - Teil 05/05

Play Episode Listen Later Jul 9, 2015


Turbulence is a ubiquitous phenomenon in astrophysical plasmas. Most of these systems exhibit a property called cross helicity, a non-zero correlation between velocity fluctuations and magnetic-field fluctuations. In the presence of a magnetic mean-field, such as in the solar wind or in the interstellar medium, cross helicity is equivalent to an imbalance between Alfven waves co- and counter-propagating with respect to the mean-field direction. Although this imbalance can have a dramatic influence on the heating and scattering rate of charged particles which propagate through the plasma, it is often neglected in computational studies of turbulent particle transport. In an effort to remedy this situation, we present numerical simulations of magnetohydrodynamic turbulence in which we can control the energy and the cross helicity of the system, without injecting kinetic or magnetic helicity as an unwanted side effect. Varying the strength of a magnetic guide-field allows us to determine the degree of anisotropy that the system assumes as a steady-state configuration. Detailed analysis proves that these simulations conform to theoretical models of realistic turbulence. The diffusion of cosmic-ray particles in turbulent plasmas is often calculated using quasilinear theory and a simplified description of the electromagnetic-field spectra. By computing the trajectories of test-particles in dynamically evolving turbulence simulations with non-zero cross helicity, we study whether such quasilinear predictions of the heating rate of charged particles are valid under realistic conditions. Theory and numerical results agree well for particles propagating at the Alfven velocity, unless resistive effects play a dominant role. Furthermore, strongly anisotropic field configurations are used to compare quasilinear pitch-angle diffusion coefficients with measurements of test-particle scattering after one gyroperiod. In particular, we focus on the scaling of the scattering rate with cross helicity. We observe excellent agreement in simulations of both balanced and imbalanced turbulence and explain the role of the magnetic moment, an approximate invariant of charged-particle motion, for pitch-angle scattering on timescales of several gyroperiods.

Wood Talk | Woodworking
WT253 – Helical Head or Not

Wood Talk | Woodworking

Play Episode Listen Later Jun 26, 2015


Shop Talk Live - Fine Woodworking
STL 84: One Big Problem with Helical Cutterheads

Shop Talk Live - Fine Woodworking

Play Episode Listen Later May 8, 2015 52:12


Helical cutterheads are all the rage for jointers and planers, but is there a white elephant in the room? Plus, your questions on finishing, mortise-and-tenon joinery, and a whole lot more.

Shop Talk Live - Fine Woodworking
STL 84: One Big Problem with Helical Cutterheads

Shop Talk Live - Fine Woodworking

Play Episode Listen Later May 8, 2015 52:12


Helical cutterheads are all the rage for jointers and planers, but is there a white elephant in the room? Plus, your questions on finishing, mortise-and-tenon joinery, and a whole lot more.

Fakultät für Physik - Digitale Hochschulschriften der LMU - Teil 05/05
Focused optical beams for driving and sensing helical and biological microobjects

Fakultät für Physik - Digitale Hochschulschriften der LMU - Teil 05/05

Play Episode Listen Later May 6, 2015


A novel and interesting approach to detect microfluidic dynamics at a very small scale is given by optically trapped particles that are used as optofluidic sensors for microfluidic flows. These flows are generated by artificial as well as living microobjects, which possess their own dynamics at the nanoscale. Optical forces acting on a small particle in a laser beam can evoke a three dimensional trapping of the particle. This phenomenon is called optical tweezing and is a consequence of the momentum transfer from incident photons to the confined object. An optically confined particle shows Brownian motion in an optical tweezer, but is prevented from long term diffusion. A careful analysis of the motion of the confined particle allows a precise detection of microfluidic flows generated by an artificial or living source in the close vicinity of the particle. Thus, the particle can be used as a sensitive optofluidic detector. For this aim, several optical tweezers at different wavelengths are integrated into a dark-field microscope, combined with a high speed camera, to achieve a precise detection of the motion of the center-of-mass of the trapped particle. With this unique experimental system, a gold sphere is used as an optofluidic nanosensor to analyze for the first time the microfluidic oscillations generated by a biological sample. Here, a freely swimming larva of Copepods serves as the living source of flow. However, even if the trapping laser wavelength is off-resonant to the plasmon resonance of the flow detector, a finite heating of the gold nanoparticle occurs which reduces the sensitivity of detection. To increase the sensitivity of the optofluidic detection, a non-absorbing, dielectric microparticle is introduced as the optofluidic sensor for the microflows. It enables a quantitative, two dimensional mapping of the vectorial velocity field around a microscale oscillator in an aqueous environment. This paves the way for an alternative and sensitive detection approach for the microfluidic dynamics of artificial and living objects at a very small scale. To this aim and as a first step, an optically trapped microhelix serves as a model system for the mechanical and dynamical properties of a living microorganism. An optical tweezer is implemented for initiating a light-driven rotation of the chiral microobject in an aqueous environment and the optofluidic detection of its flow field is established. The method is then adopted for the measurement of the microfluidic flow generated by a biological system with similar dynamics, in this case a bacterium. The experimental approach is used to quantify the time-dependent changes of the flow generated by the flagella bundle rotation at a single cell level. This is achieved by observing the hydrodynamic interaction between a dielectric particle and a bacterium that are both trapped next to each other in a dual beam optical tweezer. This novel experimental technique allows the extraction of quantitative information on bacterial motility without the necessity of observing the bacterium directly. These findings can be of great relevance for an understanding of the response of different strains of bacteria to environmental changes and to discriminate between different states of bacterial activity.

5 live Science Podcast
Naked Sci 21 Jan 13: Norovirus and the helical roots of tunnels

5 live Science Podcast

Play Episode Listen Later Feb 13, 2013 23:39


This week Dr Chris and colleagues investigate the potentcy of norovirus and new research into the genes for sociability and tunnelling (in ants and mice.)

Fundación Juan March
New frontiers between Chemistry and Biology (II): Sequence Specific Recognition of Double Helical DNA and RNA

Fundación Juan March

Play Episode Listen Later Mar 13, 1995 63:00