Podcasts about Translocation

In this episode, we discuss the relationship between the intestinal mucus layer and secretory immunoglobulin A (sIgA), highlighting both as key components of the gut's first line of defense against pathogens, toxins, and environmental stressors. We detail how dysbiosis and microbial overgrowths can impact sIgA levels and can disrupt mucus integrity and function, contributing to increased intestinal permeability and inflammation. We then examine several additional factors influencing sIgA production. Topics: 1. Introduction: Importance of Secretory IgA and Intestinal Mucus     - Intestinal epithelial lining and its protective mucus layer     - Focus on intestinal dysbiosis and sIgA   2. Anatomy of the Gastrointestinal Lining     - Intestinal lumen, microbiome, mucus layer, epithelial cells, tight junctions, lamina propria, and smooth muscle     - Role of goblet cells in mucus secretion and epithelial integrity    3. Role of the Protective Mucus Layer     - Dual function of the mucus layer as a physical and biochemical barrier     - Composition of mucus: mucins, antimicrobial peptides, immunoglobulins    4. Goblet Cells and Mucin Production     - Mechanisms of mucin secretion and hydration     - Variability in goblet cell density across the intestinal tract     - Dysfunctions linked to conditions like IBD and IBS    5. Microbial Interactions with Mucins     - Glycan structures in mucins    - Roles of commensal and pathogenic bacteria in mucin degradation and mucus turnover     - Importance of regulated mucus production for gut homeostasis    6. Dysbiosis and Mucus Degradation     - Excessive mucin degradation leading to thinning of the mucus layer     - Consequences of increased intestinal permeability and inflammation     - Role of dysbiosis in disrupting the mucus layer    7. Overview of Secretory IgA     - Introduction to secretory IgA (sIgA) and its role in mucosal immunity    - Mechanisms of immune exclusion and pathogen neutralization    8. Production and Function of Secretory IgA     - sIgA production by plasma cells in the lamina propria     - Translocation of IgA through epithelial cells into the gut lumen     - sIgA binding to mucins and its immunological role in the mucus layer    9. Factors Affecting Secretory IgA Levels     - Possible contributing factors to low sIgA levels    - Implications of low and high sIgA levels for immune defense and intestinal health    10. Interactions Between Secretory IgA and Dysbiosis     - Cyclical relationship between low sIgA, dysbiosis, and infections     - Examples of overgrowths, like candida, disrupting sIgA     - Importance of addressing immune dysregulation to break the cycle    11. Bioindividual Root Cause Approach  - Factors to consider Thank you to our episode sponsors: 1. Shop ⁠⁠Fresh Press Farms⁠⁠' Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection ⁠⁠here⁠⁠. 2. Check out ⁠Spectrum Sciences⁠' Serums and The Vitamin B12 Protocol ⁠here⁠, and use code CHLOE15 for 15% off. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

What is the root cause of your addiction? After two years of not touching alcohol, Danny shares his recent experiments with introducing the occasional alcoholic beverage back into his life. This podcast focuses on how we can often translocate energies from one addiction to another as we heal and make different life choices.  The Masters of Self University PODCAST is your highest source of Sacred Truth and Universal Wisdom, offered by Rachel Fiori, mystical teacher, psycho-energetic healer, & CEO. Join our journey of soul transformation with hosts Ellie Lee, Danny Morley, and the rest of our amazing Certified Mystical Life Coaches. Student Enrollment:   https://www.mastersofselfuniversity.com/university-enrollment Rachel's Book on Amazon:   ⁠https://shorturl.at/hkyLR Join Our Free Discord Community:   https://www.mastersofselfuniversity.com/resources#discord Masters of Self University:   ⁠⁠⁠⁠⁠https://mastersofselfuniversity.com/ Ellie's Social Media:   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@ellieyjlee⁠⁠⁠⁠   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/ellieyjlee⁠⁠⁠⁠ Danny's Social Media:   ⁠⁠⁠⁠https://www.instagram.com/dannyfmorley   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@dannyfmorley   www.youtube.com/@DannyfMorley NEW EPISODES EVERY MONDAY AND THURSDAY!

I've spent some time reflecting back on all my years practicing in hospitals, often not sleeping for extended periods, sometimes days, covering hospitals floors and ICUs, resuscitating people who experienced cardiac arrests, taking them to the cath lab to open arteries, but also witnessing people with all sorts of other health conditions: cancers, wound infections, sepsis, delirium, the various stages of dementia, and hundreds of other debilitating disease. I now recognize that, looking back, so many health conditions can be better understood in light of the contribution of the microbiome, i.e., the trillions of microbes occupying the gastrointestinal tract from mouth to anus, the nasal sinuses, the airways, the brain, the prostate, the vagina and uterus, the skin—virtually every part of the human body. We all know about acute bacterial infections. But I'm talking about something different. While microbes exert effects via a number of different routes—think the gut-brain axis, the gut-skin axis, the gut-muscle axis, effects exerted via hormones, inflammatory mediating proteins, and bacterial breakdown products. But beyond this, there is a curious phenomenon in which bacteria and fungi themselves, by a number of means, travel through the body to take up residence and cause trouble. But the “trouble” is not an infection in the conventional sense, but something different, less acute, less urgent, less dramatic, but nonetheless playing a big role in your health. This is the fascinating and scary phenomenon called “translocation,” the topic for this episode of the Defiant Health podcast. _______________________________________________________________________________For BiotiQuest probiotics including Sugar Shift, go here.A 15% discount is available for Defiant Health podcast listeners by entering discount code UNDOC15 (case-sensitive) at checkout.*_________________________________________________________________________________Get your 15% Paleovalley discount on fermented grass-fed beef sticks, Bone Broth Collagen, low-carb snack bars and other high-quality organic foods here.* For 12% off every order of grass-fed and pasture-raised meats from Wild Pastures, go here._____________________________________________________________________________MyReuteri and Gut to Glow can be found here: oxiceutics.comSupport the showBooks: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed

In July 2023 four male kākāpō were released into the fenced Sanctuary Mountain Maungatautari – part of a new habitat trial to investigate suitable locations for the growing kākāpō population. But after a further six were introduced, the kākāpō began to wander – beyond the fence. A year on, and several escapes later, what's been learned? And what's next for kākāpō in Maungatautari?  

Following the botched relocation of 263 elephants in Malawi, 10 people have died. Damages to small scale farming communities estimate in the region of $3 million. Ed Stoddard weighs in. See omnystudio.com/listener for privacy information.

In this final episode of the series, presenter Gordon Buchanan heads home to Scotland to see the work that the Beaver Trust is leading to “regenerate the beaver species to regenerate the landscape”.The Beaver Trust is a charity working to restore animals to habitats where they thrived in the past, building climate resilient landscapes across the UK and we speak to Elliot McCandless from the charity. We also chat to Tom, a fifth-generation farmer on the land but with a very different role to his predecessors.Our conversations take place, thousands of miles away from the baobab – but with similar ambitions, challenges and conflicts to navigate.We spoke to both Elliot and Tom alongside the mud banks of a beaver lake, home to the second family of beavers that were brought to Tom's land in February 2022. Translocation and reintroduction of the species in Scotland brings its own controversies with conservationists, farmers, government and local people holding different perspectives on the beaver population as we'll explore in this episode.Whilst this is the last episode of series 2, we will be publishing a special bonus edition of Beneath The Baobab in the coming weeks, bringing together all the key points and fascinating conversations from the last 9 programmes.So please follow, like or subscribe to make sure you don't miss it – and leave a written review if you've enjoyed the series; it'll help more people join us in our global conversation, beneath the baobab.Visit the website https://jammainternational.com to explore more international projects.The video of this episode can be seen here: https://youtu.be/5FOfzoGgy48https://beavertrust.orghttps://beavertrust.org/nature-boost-in-perthshire-as-second-group-of-beavers-moved-to-argaty/https://www.nature.scot Hosted on Acast. See acast.com/privacy for more information.

Just as Montana, Idaho and Wyoming politicians prepared to sign a three-state agreement on grizzly bear management, grizzly protection advocates sent a warning they plan to sue over a crucial part of the states’ plan. They don’t like the idea of trucking grizzlies from one recovery area to another as a solution to the bears’ genetic diversity. Grizzly bears remain a threatened species under federal Endangered Species Act protection. State wildlife officials say the bears are recovered and should be turned over to local state management. Grizzly defenders counter that will open the door for trophy hunting and unsustainable predator shooting. It would also put grizzlies in conflict with a different kind of advocate – black bear hunters. On this episode, Rob Chaney, Lee Montana's statewide enterprise editor and author of 'Grizzly in the Driveway' makes sense of recent grizzly bear related headlines.

As the climate changes, many species may have to relocate to survive - including the Pygmy Blue-Tongue Lizard which is receiving some assistance from scientists in South Australia.

This is the first installment of a miniseries about amphibian conservation and determination. We're calling the miniseries For the Frogs. In each episode, we will meet to one native amphibian that can be found in California's national forests. These creatures are important to ecological health, and once we get to know them, they can deepen our connections with public lands. But each of these species is in a state of decline due to overlapping threats, including pathogens, introduced predators, habitat loss, drought and wildfire. Fortunately, there is a village of specialists devoted to conserving these species despite the colossal challenge of the threat supergroup. The stories of their resolute conservation efforts, pursued through obstacles and setbacks, provides portraits of determination that we can pocket and apply to our own personal experiences with adversity. For a transcript, click here.

On this episode of Say Something Interesting Brent and Megan discuss last weekend's talk at EastLake. Other topics include @scotthepainter, whole person ministry, and cancelled flights.

The most important Gift I can give you this Christmas Season is Expectation: the strong belief that a Miracle WILL Happen. Merry Christmas!A personal collection of stories. You will laugh (Spiritual Woo Woo) cry (Kleenex Box Episode), and witness the wonder and awe of God.  Baptism of Holy Spirit Prayer Language  & Healing Fear of man, Fear of God Standing in the Glory of God Translocation and Bi-location Spiritual Vehicle and Spiritual DNA electrostatic attraction Special Song at the End Colossians 1:20 He initiated the reconciliation of all things to himself. Through the blood of the cross, God restored the original harmony. His reign of peace now extends to every visible thing upon the earth as well as those invisible things which are in heavenly realm. “Not only that but all the broken and dislocated pieces of the universe, people and things, animals and atoms, get properly fixed and fit together in vibrant harmonies, all because of his death.” — The Message.)INTENTIONAL NOW SHOW NOTES 2024 INP LISTENER SURVEY AND RAFFLE (ENTER TO WIN)INTENTIONAL NOW FB COMMUNITY   Connect with Kristen onInstagram #intentionalnowpodcast. Twitter Linkedin Patreon thank you for your support of this Podcast Website KristenWambach.comBest Resource: Kristen's #1 Money and Time-Saving ToolThank you for spending this time with me, I am honored. See you next week Kristen Music Credits  by Stockaudios from Pixabay  

The most important Gift I can give you this Christmas Season is Expectation: the strong belief that a Miracle WILL Happen. Merry Christmas!A personal collection of stories. You will laugh (Spiritual Woo Woo) cry (Kleenex Box Episode), and witness the wonder and awe of God.  Baptism of Holy Spirit Prayer Language  & Healing Fear of man, Fear of God Standing in the Glory of God Translocation and Bi-location Spiritual Vehicle and Spiritual DNA electrostatic attraction Special Song at the End Colossians 1:20 He initiated the reconciliation of all things to himself. Through the blood of the cross, God restored the original harmony. His reign of peace now extends to every visible thing upon the earth as well as those invisible things which are in heavenly realm. “Not only that but all the broken and dislocated pieces of the universe, people and things, animals and atoms, get properly fixed and fit together in vibrant harmonies, all because of his death.” — The Message.)INTENTIONAL NOW SHOW NOTES 2024 INP LISTENER SURVEY AND RAFFLE (ENTER TO WIN)INTENTIONAL NOW FB COMMUNITY   Connect with Kristen onInstagram #intentionalnowpodcast. Twitter Linkedin Patreon thank you for your support of this Podcast Website KristenWambach.comBest Resource: Kristen's #1 Money and Time-Saving ToolThank you for spending this time with me, I am honored. See you next week Kristen Music Credits  by Stockaudios from Pixabay  

Have you ever wondered what would happen if we could use natural teeth instead of implants? Like, could we gently extract a 3rd molar and move it up in place of an extracted 1st molar? Listen to this fascinating Fast Fact with Katrina Sanders! Resources:More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/ Katrina Sanders Website: https://www.katrinasanders.com  Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/  Pini Prato, G., Franceschi, D., Pace, R., & Di Gianfilippo, R. Translational approach to tooth autotransplantation: A 27‐year case study. Clinical Advances in Periodontics.

Have you ever wondered what would happen if we could use natural teeth instead of implants? Like, could we gently extract a 3rd molar and move it up in place of an extracted 1st molar? Listen to this fascinating Fast Fact with Katrina Sanders! Resources:More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/ Katrina Sanders Website: https://www.katrinasanders.com  Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/  Pini Prato, G., Franceschi, D., Pace, R., & Di Gianfilippo, R. Translational approach to tooth autotransplantation: A 27‐year case study. Clinical Advances in Periodontics.

In this episode, we discuss the consequences of moving problem critters around on the landscape, and reasons why wildlife biologists do not recommend translocation of wildlife as a humane option when removal is needed.

In this episode, we discuss the consequences of moving problem critters around on the landscape, and reasons why wildlife biologists do not recommend translocation of wildlife as a humane option when removal is needed.  

This Part 4 Listening is all about moving elephants. In the lesson you'll learn about: using word prompts to keep your place using intonation and sentence stress to identify answers using spelling patterns and plurals to get the right answers The full transcript is available in the Bronze Membership on my website. https://ieltsetc.com/2023/10/ielts-listening-part-4-keeping-up-with-the-speaker/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/ieltsetc/message

References Molecular Neurobiology 2022. volume 59, pages 4223–4241 Hum Genet. 1994 Jan;93(1):67-73 Mol Cell Biol. 2012 Jan;32(1):126-38 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

It's been around 2 months since the first translocation of kākāpō to mainland Aotearoa. To check in on how these taonga are going in Te Ika a Māui, we're joined by Ngai Tahu kākāpō recovery group representative, Tāne Davis. 

References Journal of Immunology Research Article ID 8263829 JAMA. 2021 Jun 15; 325(23): 2392–2393. Thyroid. 2014 Feb 1; 24(2): 371–382. Pol Arch Intern Med. 2022 Mar 30; 132(3): 16222. FEBS Letters.1997. (414): 258-262 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Cleveland native Justin Telep loves to fish. It makes sense then that he loves his job as a Field Biologist at the Sewer District. Justin and his team study the health of aquatic organisms in area streams to determine water quality. He talks about a NEORSD project to re-introduce native fish into a once-polluted Plum Creek. We also discuss fishing opportunities on Lake Erie ("the walleye capital of the world") and Justin shares an easy recipe for crispy fish tacos.Some acronyms used in this episode:IBI: Index of Biotic Integrity, an indicator of the health of a fish communityMIwb: Modified Index of Well-Being, another method of determining the health of the fish communityICI: Invertebrate Community Index, which measures the health of bugs in the stream

What methods could be employed after a massive mule deer population die-off?     Below are some options biologists generally turn to try and help any population: Habitat Restoration, Disease Monitoring and Control, Wildlife Population Monitoring, Conservation Breeding and Translocation, Public Awareness, and Education, Collaboration, and Partnerships.   Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.05.547674v1?rss=1 Authors: Demirbas, B., Filina, O., Louisse, T., Goos, Y., Sanchez-Romero, M. A., Olmedo, M., van Zon, J. Abstract: FOXO transcription factors are highly conserved effectors of insulin and insulin-like growth factor signaling, that are crucial for mounting responses to a broad range of stresses. Key signaling step is the stress-induced translocation of FOXO proteins to the nucleus, where they induce expression of stress response genes. Insulin signaling and FOXO proteins often control responses that impact the entire organism, such as growth or starvation-induced developmental arrest, but how body-wide coordination is achieved is poorly understood. Here, we leverage the small size of the nematode C. elegans, to quantify translocation dynamics of DAF-16, the sole C. elegans FOXO transcription factor, with single-cell resolution, yet in a body-wide manner. Surprisingly, when we exposed individual animals to constant levels of stress that cause larval developmental arrest, DAF-16/FOXO translocated between the nucleus and cytoplasm in stochastic pulses. Even though the occurrence of translocation pulses was random, they nevertheless exhibited striking synchronization between cells throughout the body. DAF-16/FOXO pulse dynamics were strongly linked to body-wide growth, with isolated translocation pulses causing transient reduction of growth and full growth arrest observed only when pulses were of sufficiently high frequency or duration. Finally, we observed translocation pulses of FOXO3A in mammalian cells under nutrient stress. The link between DAF-16/FOXO pulses and growth provides a rationale for their synchrony, as uniform proportions are only maintained when growth and, hence, pulse dynamics are tightly coordinated between all cells. Long-range synchronization of FOXO translocation dynamics might therefore be integral also to growth control in more complex animals. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

India's ambitious cheetah relocation project got a shot in the arm when one of the translocated females gave birth to four cubs in March. These were the first cheetah cubs to be born in India since the species went extinct in the country 70 years ago. But in an unfortunate turn of events, three out of the four cubs have died, and the fourth one, also reported to be very weak, is under close medical monitoring. The Environment Ministry in a press release has claimed that the survival rate of cheetah cubs is only 10%. Does that mean that the deaths of the three cheetah cubs were along expected lines? Shouldn't the survival rate be higher in the absence of predators? What are the various factors that could have a bearing on the survival of cheetah cubs? 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.03.535309v1?rss=1 Authors: Peh, A., Dinakis, E., Nakai, M., Muralitharan, R. R., Rupasinghe, S., Wilson, J. L., Wong, C. H. Y., Jama, H., Barker, C. M. O., Modarresi, M., Kemp-Harper, B. K., Zheng, T., Marques, F. Z., Broughton, B. R. S. Abstract: We provide evidence that stroke-induced gut breakdown results in bacteria translocation to the ischaemic mouse brain. Inhibition of sympathetic tone reduced bacterial load in the post-stroke brain and reduced functional deficits without altering cerebral apoptosis, neuroinflammation or infarct volume. These findings indicate that the activation of the sympathetic nervous system after stroke promotes gut-derived bacteria to enter to the brain, and this process worsens motor function in mice. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.27.530219v1?rss=1 Authors: Calabrese, C., Nolte, H., Pitman, M. R., Ganesan, R., Lampe, P., Laboy, R., Ripa, R., Fischer, J., Chipurupalli, S., Gutierrez, S., Polara, R., Thomas, D., Pitson, S. M., Antebi, A., Robinson, N. Abstract: TFEB is a master regulator of autophagy, lysosome biogenesis and mitochondrial metabolism that works, and immunity, primarily through transcription controlled by cytosol-to-nuclear translocation. Emerging data indicate additional regulatory interactions at the surface of organelles such as lysosomes. Here we show that TFEB has a non-transcriptional role in mitochondria, regulating the electron transport chain complex I to down-modulate inflammation. Proteomic analysis revealed extensive TFEB co-precipitation with several mitochondrial proteins, whose interactions are disrupted upon infection with S. Typhimurium. Localization of TFEB in the mitochondrial matrix was confirmed by high resolution confocal microscopy and biochemistry with translocation dependent on a conserved N-terminal TOMM20-binding motif enhanced by mTOR inhibition. Within the mitochondria, TFEB and protease LONP1 antagonistically co-regulate complex I, reactive oxygen species and the inflammatory response. Consequently, during infection, lack of TFEB specifically in the mitochondria exacerbates the expression of pro-inflammatory cytokines, contributing to innate immune pathogenesis. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

In a meta-analysis of six eligible studies, results validated that periodontitis was significantly associated with IBD, but the mechanism was still undetermined. by Anne O. Rice, BS, RDH, CDP, FAAOSH   Read Article Here: https://www.rdhmag.com/patient-care/patient-education/article/14284883/the-translocation-of-bacteria-inflammatory-bowel-disease 

Brought to you by Community-Minded Alpine Toyota   In the episode Mark and Curtis talk turkey with Matt Besko, Director of Wildlife and Licensing for the province of Alberta. The topics they cover include the moving wild turkey from BC to Alberta, the difference in attitudes towards managing wild turkey in BC versus Alberta, the philosophy of non native wild turkeys in an altered landscape, valuing wild turkeys, wild turkey-human conflict, myths about wild turkey, adaptive management, Alberta's wild turkey Minister tags, hunting wild turkey, iconic hunting cocktails to represent the regions of Canada and gator tails.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.31.526442v1?rss=1 Authors: Marchesan, E., Nardin, A., Mauri, S., Di Paola, S., Chinellato, M., von Stockum, S., Chakraborty, J., Herkenne, S., Basso, V., Schrepfer, E., Marin, O., Cendron, L., Medina, D. L., Scorrano, L., Ziviani, E. Abstract: Selective removal of dysfunctional mitochondria via autophagy is crucial for the maintenance of cellular homeostasis. This event is initiated by the translocation of the E3 ubiquitin ligase Parkin to damaged mitochondria, and it requires the Serine/Threonine-protein kinase PINK1. In a coordinated set of events, PINK1 operates upstream of Parkin in a linear pathway that leads to the phosphorylation of Parkin, Ubiquitin, and Parkin mitochondrial substrates, to promote ubiquitination of outer mitochondrial membrane proteins. Ubiquitin decorated mitochondria are selectively recruiting autophagy receptors,which are required to terminate the organelle via autophagy. In this work we show a previously uncharacterized molecular pathway that correlates the activation of the Ca2+-dependent phosphatase Calcineurin to Parkin-dependent mitophagy. Calcineurin downregulation or genetic inhibition prevents Parkin translocation to CCCP-treated mitochondria, and impairs stress-induced mitophagy, whereas Calcineurin activation promotes Parkin mitochondrial recruitment and basal mitophagy. Calcineurin interacts with Parkin, and promotes Parkin translocation in the absence of PINK1, but requires PINK1 expression to execute mitophagy in MEF cells. Genetic activation of Calcineurin in vivo boosts basal mitophagy in neurons, and corrects locomotor dysfunction and mitochondrial respiratory defects of a Drosophila model of impaired mitochondrial functions. Our study identifies Calcineurin as a novel key player in the regulation of Parkin translocation and mitophagy. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.30.522351v1?rss=1 Authors: Ma, Q., Yao, C., Wu, Y., Wang, H., Fan, Q., Yang, Q., Xu, J., Dai, H., Zhang, Y., Xu, F., Lu, T., Wang, C. Abstract: Neurological disorders after severe acute pneumonia have been attacked much attention in recent years. However, the underline mechanisms remain not very clear. Here we show that these neurological syndromes after severe acute pneumonia are partly attributed to the translocation of bacteria from the lung to the brain during acute pneumonia. We detected an emerging and increased bacteria in the brain tissue of mice with lipopolysaccharide-induced experimental severe pneumonia. Interestingly, using 16S rDNA amplification sequencing, similarities were found between the brain's flora species and those of the lungs, indicating the bacteria in the brain may come from the lung. We also observed the impairment of the lung-blood barrier and brain-blood barrier, simultaneously, allowing lung bacteria invade the brain during pneumonia. An elevated microglia and astrocytes activation markers signature though bacterial infection-related pathways are observed by single-cell RNA sequencing, indicating a bacteria-induced disruption of brain homeostasis. Rapamycin delivered by platelet-derived extracellular vesicles provides an effective strategy to rescue the brain microenvironment and neurological disorders. Collectively, we identify lung bacteria that play a role in altering brain homeostasis, which provides new insight into the mechanism of neurological syndromes after severe pneumonia. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.29.522198v1?rss=1 Authors: Wang, D., Zheng, X., Chai, L., Zhao, J., Zhu, J., Li, Y., Yang, P., Mao, Q., Xia, H. Abstract: FAM76B has been reported to be a nuclear speckle localized protein with unknown function. In this study, FAM76B was first demonstrated to inhibit the NF-{kappa}B-mediated inflammatory pathway by affecting the translocation of hnRNPA2B1 in vitro. We further showed that FAM76B suppressed inflammation by regulating the NF-{kappa}B pathway in vivo using a traumatic brain injury (TBI) model in FAM76B knockout mice. Lastly, FAM76B was shown to interact with hnRNPA2B1 in human tissues taken from patients with acute, organizing, and chronic TBI, and with different neurodegenerative diseases. The results suggested that FAM76B mediates neuroinflammation by influencing the translocation of hnRNPA2B1 in vivo during TBI repair and neurodegenerative diseases. In summary, we for the first time demonstrated the role of FAM76B in regulating inflammation and further showed that FAM76B could regulate the NF-{kappa}B-mediated inflammatory pathway by affecting hnRNPA2B1 translocation, which provides new information for studying the mechanism of inflammation regulation. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Translocation and the reintroduction of beavers are valuable resources in restoring areas that have experienced drought or abuse. Another option is beavery mimicry, using beaver tactics through a series of small rock dams, sod mats, and woven willows to mimic a beaver dam. There are pros and cons to these solutions: Translocating beaver are a lot cheaper than beaver mimicry but beaver tend to build wherever they want.   Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL

Reference Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

In this episode, Prof. Van de Heyning shares 3 harmful results which could occur when an electrode is inserted into the cochlea and how we can prevent it. He also discusses why straight electrodes are a suitable and preferable choice for robotic and CI surgery.

The differences between the two main types of cochlear implant electrode arrays are explained in this episode by Dr. Hans Thomeer. Specifically, how these two electrode designs and surgical approaches can affect translocation after the electrode insertion, and what might be a better option.

Today I am joined by Christina as she shares her story with miscarriages, genetic testing, IVF, and more. Christina has been so strong and has handled her struggles with complete grace. I'm sure that this episode will help someone out there who has gone through or is currently experiencing a similar situation. Please remember that neither of us are doctors or medical specialists. Please consult your doctor your individual health. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

This is perhaps the most important podcast I've recorded so far, because it deals with a topic that is becoming increasingly relevant with the growing popularity of psychedelics, occult practices and technology.On this episode I speak with Norwegian healer and author Are Thoresen about his 2020 book Demons and Healing: The Reality of the Demonic Threat and the Doppelgänger in the Light of Anthroposophy: Demonology, Christology and Medicine.Are Thoresen was born in Norway in 1952. A doctor of veterinary medicine, he has also studied anthroposophic medicine, homeopathy, acupuncture, osteopathy and agriculture. Since 1981 he has run a private holistic practice in Sandefjord, Norway, for the healing of small animals and horses, as well as people. He has lectured widely, specializing in veterinary acupuncture, and has published dozens of scholarly articles. In 1984 he started to treat cancer patients, both human and animals, and this work has been the focus of much of his recent research. He is the author of Demons and Healing and several other books on complementary medicine.In our conversation Are and I discuss many aspects of demonic entities and possession — how they are created, how they cause physical and mental disease, and how we can transform them and protect ourselves from them. In his books Are writes in great detail about these entities, and trust me, it can begin to feel pretty complex and overwhelming. In an attempt to keep this conversation grounded and relatable, I thought it would be helpful if I shared my personal experience with a demonic entity that I encountered while experimenting with astral projection as a teenager, and how I dealt with it 20 years later in the Santo Daime ayahuasca church. This experience is something that I've only talked about with 2 or 3 people over the years, and while I'm a little reluctant to share it publicly, I feel that it could actually save someone's life. It's that important.•••Timestamps4:20 Introduction8:22 Early spiritual life (Anthroposophy, spirits, Christianity)13:10 Demons, entities, psychedelics & disease16:35 Possession & translocation of entities20:40 Guarding against opening portals21:40 My experience with a demonic entity28:50 Are diagnoses my opening29:57 Closing portals32:00 Types of entities & disease38:49 Different types of attacks40:25 Ayahuasca and opening portals42:20 Protecting yourself in ceremony45:00 Translocation vs. Transformation of entities46:10 Strengthening the “I”53:16 The protective power of music 53:56 The dangers of technology57:30 Memory of water & homeopathy58:49 What psychedelic “therapy” is getting wrong1:02:15 “Opening the middle” in electronic devices and in healing work1:13:40 What changed after Christ 1:16:36 The need for spiritual warriors and spiritual healing•••Support the Podcast!If you'd like to join the conversation and help support the podcast, please considering becoming a member of the growing Medicine Path tribe at patreon.com/medicinepath. You can also follow me on Instagram @revealingthesoul. I love hearing from listeners, so please feel free to reach out on social media or email me at hello@brianjames.ca•••Links:Donate: http://ko-fi.com/brianjames / http://paypal.me/medicinepathyogaPatreon: http://patreon.com/medicinepath Coaching & Books: http://brianjames.ca Yoga Courses: http://medicinepathyoga.comMusic: Royal Fern by Green House (https://green-house.bandcamp.com) See acast.com/privacy for privacy and opt-out information.

This week, Nathan talks about some great plants are blooming in his landscape this week! You might be seeing some plants, particularly gardenias, revealing some yellow foliage. Most folks think that yellowing leaves means the plant is dying, but Nathan says it's quite the opposite. Certain yellow leaves means that the plant is actually growing! Lastly, if you have some overgrown shrubs or trees, Nathan explains how you can rejuvenate them and "start them over."

Adolescent and Young Adult (AYA) Oncology Focusing on Translocation RCC Co-Host: Nick G. Cost, MD Outline: Topic 1: Adolescents with cancer are different from both children and older adults with cancer Topic 2: Differences in biology Topic 3: Differences in clinical behavior Topic 4: Specific clinical trial options Topic 5: Summary – “Now what? What should I do the next time I see an AYA with kidney cancer?”

In this week's episode we chat to Fiona. She found out she had inherited a Robertsonian Translocation from her father and suffered 3 miscarriages. She was in the process of starting IVF when she found out she was pregnant with her now 10 month old daughter.  --------------------------------Thanks for listening to the podcast. Please don't forget to subscribe, rate, review and share.Visit our website where you can find out a bit about us, read the blog and even 'purch our merch' via the online shop!Find out more about our courses including  THE PATHWAY TO RECOVERY which is designed to support, nuture and empower you following the loss of a baby. Our September course is now sold out but keep you eyes peeled for details about the October PTR as well as the new Pregnancy After Loss and Trying To Conceive courses.Contact us via social media platforms or email info@theworstgirlgangever.co.ukYou'll find us on...FacebookInstagramTwitteror you can join the TWGGE Facebook Support GroupIt's time to break the silence and open up the dialogue around the topics of miscarriage and pregnancy loss. No more shame, no more taboo, lets ditch it for our children; the ones that will come, the ones that are and the ones that never came to be.--------------------------------

Traci McCombs is a seasoned analyst at the NIH and an active-duty Army Spouse. After back-to-back miscarriages and the discovery of balanced Robertsonian translocation and cancer, she naturally conceived and gave birth to a daughter and later a son. Buy Traci's book "My Miscarriage" HERE Follow Traci: @tracidmccombs Follow Arden: @ardenmcartrette Follow TMD: @themiscarriagedoula` Interested in sharing your story? CLICK HERE The miscarriage doula is a service and resource for women and couples who are going through miscarriage or navigating life afterward. My approach is to help you identify healthy coping strategies, be a safe place for you to discuss what you've been through, and provide resources and education to help you as you move forward in your journey. Learn more HERE --- Send in a voice message: https://anchor.fm/arden-cartrette/message Support this podcast: https://anchor.fm/arden-cartrette/support

In this weeks episode Martin and Paul cover the translocation of large groups of people from big government states like California and New York to smaller government states like Texas and Florida. They cover what they suspect is the reason for the migration and what needs to happen so that new new digs don't turn…

In this episode we discuss basic information about being a Balanced Translation carrier and share our experience about our journey so far. We talk about our discovery of unbalanced translocation chromosomes on our miscarriage tissue and where that has lead us to now. Trigger warnings: miscarriages mentioned. Email us comments at: balancedtranslocationpodcast@gmail.com

Arden chats with her friend Steffi about recurrent pregnancy loss, when miscarriage is the reason for an infertility diagnosis, and how OCD (obsessive-compulsive disorder) can be triggered during a fertility journey and then motherhood after. In this episode, we hear Steffi's story through two miscarriages, a balanced translocation diagnosis (and what that means), having to do IVF to make a baby, and then her. scary first trimester with her double rainbow, Junie. *Support The Miscarriage Doula Podcast for as low as $0.99/month! Click here to learn more. Follow Arden: @ardenmcartrette Follow TMD: @themiscarriagedoula Visit themiscarriagedoula.co for information on private and group support services if you're going through loss or struggling with grief. --- Send in a voice message: https://anchor.fm/arden-cartrette/message Support this podcast: https://anchor.fm/arden-cartrette/support

What's the science behind beaver translocation? And why should it form part of an positive management strategy? As part of our content to celebrate British Science Week and International Women's Day, we talk to top beaver ecologist Dr Roisin Campbell-Palmer. With an impressive career and background in animal management and welfare, field operations and beaver/human conflict management, Roisin imparts heaps of knowledge and wisdom when it comes to bringing these mammals back to British rivers safely, and responsibly.  Coming up: Eva hits Sophie with an epic #FactOff, and brains are teased in another quiz! For more information on eco anxiety and professional advice, please click here. Are you a beaver believer? We want to hear from you: Beaver Trust.  Want more beaver? Please leave us a lovely little review, so we can bring the joy of beavers to more ears!  Hosted by Sophie Pavelle and Eva Bishop.  Produced and edited by Emma Brisdion.

This episode of the Ground Shots Podcast is a conversation between Kelly Moody and Gabe Crawford.   We haven't done an episode together since we were on the Colorado Trail this past summer. So, we wanted to talk about the research we have been doing since we got off of the trail, and while hermiting a bit in our bell tent camp along a riparian corridor, outside of Durango, Colorado. We've been thinking a lot about what land tending means, and definitions of ‘wildness,' and ‘wilderness' since hiking the trail, and wanted to spend some time looking into the literature out there on conservation, ecology and agriculture. We've only touched the surface with our research, but wanted to talk about it on air with ya'll here, and connect some distant tendrils of what we're finding through conversation. Above all, our goal has been to try to understand why anthropogenic (human tended and co-created) landscapes are ignored in scientific literature, hence why ‘wild-tending' seems far-fetched to some folks. And, we want to understand the deeper origins of the invasion biology field of conversation and how it may be connected to ethnocentrism, racism, unexamined colonialist assumptions in the fields of history and science, and more. Since this episode was recorded and edited, we have migrated to where my family is in southern Virginia for the rest of the winter and are trying to adjust to a different culture, climate and navigating the pandemic without public land.   In this episode of the podcast, we talk about:   the oppressive colonizing force of the Christian church institution in Europe and how this influenced the suppression of land based spirituality some etymology of ‘heretic,' ‘heathen,' ‘villan,' and ‘pagan' how the disregard for historic anthropogenic landscapes is connected to the obsession with ‘pristine' ecology and ‘wilderness' notions how Eurocentric ideas about agriculture influenced what colonists saw as ‘uncivilized' or ‘cultivated' on turtle island and how these ethnocentric biases ignored anthropogenic landscapes the white supremacy inherent in the western scientific interpretation of human cultivation, land management and indigenous influence on ecology biases in the historical accounts of indigenous cultures and the landscapes of Turtle Island, South America, etc. by European explorers yet many of these accounts are used to determine ecological baselines in conservation goals some of the origins of emotive, moral and value based language in invasive biology and conservation fields the roots of why conservationism is wary to include indigenous peoples in its preservation of ‘pristine wilderness' and how the creation of baselines that doesn't include indigenous land management practices, even though the ecological baselines that might be their goals were anthropogenic landscapes the history of national parks extirpating natives off of their land in order to ‘preserve' an idea of ‘wilderness' and how they continue to ignore how the humans there were a part of creating and managing the landscapes the affluence associated with conservation culture and the western ideas of the museumification of ‘pristine land' the misinformation in the academic literature of invasion biology created through confirmation biases and disproven theories continuing to be referenced as facts   Links: A slew of resources related to what we chatted about on the podcast can be found below. Subscribe to our email newsletter, found at the bottom of this link section, for updates on when we will be offering some classes related to these topics. “Rambunctious Garden : Saving Nature in a Post-Wild World” by Emma Marris “Beyond the War on Invasive Species” by Tao Orion “Keeping it Living: : Traditions of Plant Use and Cultivation on the Northwest Coast of North America” by Nancy Turner “The Burning Times” by Jeanne Kalogridis Southwest Colorado Wildflowers entry on Triteleia grandiflora (Wild Hyacinth, Large-flowered Onion), where the botanists mention the likelihood that the Utes brought it through trade from the Pacific Northwest and planted it to eat, given it is a very disjunct species from where it is normally found “The Ecology of Invasions by Animals and Plants” by Charles Elton “Charles S. Elton and the Dissociation of Invasion Ecology from the Rest of Ecology” by Mark Davis “Don't Judge Species on Their Origins” by Mark Davis and Matthew K. Chew “1491": New Revelations of the Americas before Columbus” by Charles Mann ECOLOGISTS, ENVIRONMENTALISTS, EXPERTS, AND THE INVASION OF THE ‘SECOND GREATEST THREAT' by Matthew K. Chew “The rise and fall of biotic nativeness: a historical perspective” by Matthew K. Chew “Invasions: the trail behind, the path ahead, and a test of a disturbing idea” by Angela Moles "Is rapid evolution common in introduced plant species?” by Angela Moles Torreya Guardians website: “Assisted Migration (Assisted Colonization, Managed Relocation, Translocation) and Rewilding of Plants and Animals in an Era of Rapid Climate Change” “Quantifying Threats to Imperiled Species in the United States: Assessing the relative importance of habitat destruction, alien species, pollution, overexploitation, and disease” by David Wilcove (this article is routinely cited as the reference for invasive species being the second greatest threat to biodiversity when it doesn't even say that, alongside Edward O. Wilson's 1992 book, “The Diversity of Life”) “Invasion Biology : Critique of a Pseudoscience” by David Theodoropoulos “Environmental determinism”: This is a wikipedia article on the history of environmental determinism in the contest of western colonialism and how this philosophy was used to justify abuses to human rights. “How conservation became colonialism” BY ALEXANDER ZAITCHIK “Forgotten Fires : Native Americans and the Transient Wilderness” by Omer C. Stewart   Call the podcast and leave us a message (you give us permission to potentially air it on the podcast): 1-434-233-0097   Support the podcast on Patreon to contribute monthly to our grassroots self-funding of this project  For one time donations to support this work: Paypal : paypal.me/petitfawn VENMO: @kelly-moody-6 Cashapp: cash.app/$groundshotsproject     Our website with an archive of podcast episodes, educational resources, past travelogues and more: http://www.ofsedgeandsalt.com  Our Instagram pages: @goldenberries / @groundshotspodcast Join the Ground Shots Podcast Facebook Group to discuss the episodes Subscribe to our newsletter for updates on the Ground Shots Project Theme music: 'Sweat and Splinters' by Mother Marrow Interstitial Music: “Big Ivy” by the Resonant Rouges Hosted by: Kelly Moody Produced by: Kelly Moody and Gabe Crawford

Resistance Recovery Founder Piers Kaniuka and healer and author Are Thoresen discuss Illness, Translocation, and the Christ. Recorded on December 2, 2020.To learn more about Are's publications visit https://www.rudolfsteinerbookcentre.c....Resistance Recovery (RR) is reimagining addiction, recovery, and community in the 21st century. Piers Kaniuka, MTS, MS has worked with thousands of addicts and alcoholics in his 25+ years in the field. Discover RR's new paradigm of addiction recovery by visiting http://resistancerecovery.com.Visit the RR YouTube channel: https://www.youtube.com/c/RESISTANCERECOVERYSign-up for Long Threads and get Resistance Recovery news: https://mailchi.mp/ddc8023bec67/welcometoresistancerecoverySupport this podcast at — https://redcircle.com/resistance-recovery/donations

Bridgette and Madison were best friends. Then sisters-in-law. One conceived. The other didn't. Both were in for surprises. This is their story. -- For more about Sarah's Laughter, please visit our website at sarahs-laughter.com. Our podcast-only site is podcast.sarahs-laughter.com. You can follow us on social media linked here: Sarah's Laughter on Facebook & Instagram, and @sarahs_laughter & @jasonforbus on Twitter. Sarah's Laughter also holds the Baby Steps Fun Run, where we give away a $10,000 grant for expenses related to either adoption or fertility treatment. We also partner with local SART-listed fertility clinics to give away IVFs at the event. Check babystepsfunrun.com for details and schedule. *** Sarah's Laughter is a 501(c)(3) nonprofit public charity. If you'd like to help support what we do, including this podcast, please visit sarahs-laughter.com/give. Thank you. -- Want to share your infertility story on this podcast? Email us at podcast@sarahs-laughter.com