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What if breast cancer treatment didn't have to mean invasive surgery, long recoveries, or losing part of yourself? In this episode I'm sitting down with Dr. Dennis Holmes, a world-renowned breast surgeon and pioneer in cryoablation, a groundbreaking, minimally invasive procedure that uses extreme cold to destroy cancer cells. Dr. Holmes explains how cryoablation works, why patients are demanding it as an alternative to traditional surgery, the pros and cons compared to traditional surgery, and how this therapy preserves the breast, while delivering comparable success rates to standard surgery. Empowered, patient-centered options is what this episode is all about. ...Listen in to learn more!
Superpowers for Good should not be considered investment advice. Seek counsel before making investment decisions. When you purchase an item, launch a campaign or create an investment account after clicking a link here, we may earn a fee. Engage to support our work.Watch the show on television by downloading the e360tv channel app to your Roku, LG or AmazonFireTV. You can also see it on YouTube.Devin: What is your superpower?Diana: Relentless passion.Breast cancer treatment is long overdue for a revolution. Diana Tucker, CEO of SenoGuard, is leading the charge with an innovative alternative to post-lumpectomy radiation. Using advanced cryoablation technology, SenoGuard freezes the cavity where a tumor is removed, eliminating residual cancer cells in one procedure.Radiation has been the standard of care for decades, but it comes with significant physical, emotional, and financial costs. Diana explained in today's episode, “Radiation is horrible both clinically and cosmetically. It changes the shape, size, and feel of the breast. Many women face long-term emotional and physical side effects.” She shared the tragic story of a young breast cancer survivor whose radiation treatment ultimately damaged her heart. “I am very passionate about eliminating radiation if at all possible,” she said.SenoGuard's approach simplifies treatment. “The patient goes in for her tumor excision, and immediately we freeze the cavity where the tumor has been removed,” Diana said. “It's one and done. The patient can go back to work the very next day.” This innovation not only reduces the physical toll on patients but also addresses significant disparities in access to care. Many women forego lumpectomies because daily radiation sessions are unaffordable or inaccessible, especially in rural areas. Diana noted, “Almost 30% of women who qualify for a lumpectomy choose mastectomy instead because they can't afford the time or cost of radiation.”To bring this groundbreaking technology to market, SenoGuard is raising capital through a regulated investment crowdfunding campaign on WeFunder. Diana emphasized the importance of public support, saying, “Everybody knows someone who has had breast cancer. By investing, people feel they are not just supporting a cause but making a difference for society.”SenoGuard's cryoablation technology has the potential to transform breast cancer treatment, making it less toxic, more accessible, and kinder to patients. By supporting their crowdfunding campaign, you could help bring this life-changing innovation to millions of women.tl;dr:Diana Tucker shared how SenoGuard's cryoablation technology eliminates the need for post-lumpectomy radiation.Radiation's side effects often force women to choose mastectomies, highlighting the need for better options.SenoGuard's innovation reduces treatment time, costs, and disparities in accessing breast cancer care.Diana described her relentless passion and how it drives her to overcome challenges in her work.SenoGuard is raising funds via a WeFunder campaign to bring this life-changing technology to market.How to Develop Relentless Passion As a SuperpowerDiana Tucker's superpower is her relentless passion for solving problems she truly believes in. As she explained in today's episode, “When I have a sincere understanding, I become very passionate, enthusiastic, and relentless to get that…across the finish line.” Her superpower drives her to tackle challenges with unwavering determination, especially when the stakes are high.Story Illustrating SuperpowerDiana shared a story from her early career, where she was tasked with bringing a French ophthalmology solution to the U.S. market. “The CEO told me, ‘If you can figure out how to bring this over to America, you have a job. If you can't, you're fired.'” Fueled by determination, she successfully introduced the technology, which became the standard of care. Years later, an ophthalmologist recognized her contribution with heartfelt gratitude, highlighting the profound and lasting impact of her work.Tips for Developing the SuperpowerFind Your Passion: Identify problems that deeply resonate with you to fuel your enthusiasm and drive.Share Your Vision: Build a team by inspiring others with your passion and clear vision.Never Give Up: When faced with roadblocks, find creative workarounds to keep moving forward.Believe in Yourself: Confidence in your abilities is key to overcoming challenges and achieving your goals.By following Diana's example and advice, you can make relentless passion a skill. With practice and effort, you could make it a superpower that enables you to do more good in the world.Remember, however, that research into success suggests that building on your own superpowers is more important than creating new ones or overcoming weaknesses. You do you!Guest ProfileDiana Tucker (she/her):CEO, SenoGuardAbout SenoGuard: SenoGuard is pioneering a transformative approach to breast cancer treatment by offering a radiation-free alternative following lumpectomy. Our innovative technology uses advanced cryoablation--freezing residual cancer cells during surgery--to eliminate the need for weeks of post-op radiation.This method significantly reduces patient burden, especially for the 28% who face barriers like distance, cost, or time constraints.Supported by National Science Foundation grants, SenoGuard's solution is designed to be accessible in community hospitals, expanding treatment options globally. Led by a seasoned team with over a century of combined experience in women's healthcare, SenoGuard is committed to enhancing patient outcomes and accessibility.Website: SenoGuard.comCompany Facebook Page: facebook.com/senoguardOther URL: wefunder.com/senoguardincBiographical Information: Diana Tucker is a strategic marketing executive with a distinguished track record in launching and growing innovative, paradigm-shifting medical technologies. With deep expertise in market analysis and opportunity identification, she has led high-impact global marketing initiatives across diagnostics, medical devices, and oncology. Known for her ability to anticipate market trends and apply creative strategies that drive adoption of innovative products, Diana has held leadership roles at companies such as Agendia, AMO, and J&J; as well as being a contributing editor for Thompson Reuters Biomedical Business International newsletter covering financial impacts of emerging technologies across all surgical specialties worldwide. Diana has continually demonstrated her talent for turning unmet clinical needs into successful business opportunities. Diana holds a B.S. in Molecular & Cellular Biology from UC Irvine and an MBA in Marketing from Pepperdine University.Personal Facebook Profile: facebook.com/dianatuckerLinkedin: linkedin.com/in/dianaltuckerSupport Our SponsorsOur generous sponsors make our work possible, serving impact investors, social entrepreneurs, community builders and diverse founders. Today's advertisers include FundingHope, Rancho Affordable Housing (Proactive), and Dopple. Learn more about advertising with us here.Max-Impact MembersThe following Max-Impact Members provide valuable financial support:Carol Fineagan, Independent Consultant | Hiten Sonpal, RISE Robotics | Lory Moore, Lory Moore Law | Marcia Brinton, High Desert Gear | Matthew Mead, Hempitecture | Michael Pratt, Qnetic | Dr. Nicole Paulk, Siren Biotechnology | Paul Lovejoy, Stakeholder Enterprise | Pearl Wright, Global Changemaker | Ralf Mandt, Next Pitch | Scott Thorpe, Philanthropist | Sharon Samjitsingh, Health Care Originals | Add Your Name HereUpcoming SuperCrowd Event CalendarIf a location is not noted, the events below are virtual.Impact Cherub Club Meeting hosted by The Super Crowd, Inc., a public benefit corporation, on August 19, 2025, at 1:30 PM Eastern. Each month, the Club meets to review new offerings for investment consideration and to conduct due diligence on previously screened deals. To join the Impact Cherub Club, become an Impact Member of the SuperCrowd.SuperCrowdHour, August 20, 2025, at 12:00 PM Eastern. Devin Thorpe, CEO and Founder of The Super Crowd, Inc., will lead a session on "Your Portal, Your Future: How to Choose the Right Reg CF Platform." With so many investment crowdfunding portals available today, selecting the right one can be overwhelming for both founders and investors. In this session, Devin will break down the critical factors to consider—such as platform fees, audience demographics, compliance support, industry focus, and overall user experience. Whether you're a founder planning a raise or an investor exploring where to put your dollars to work, you'll walk away with a clearer understanding of how to evaluate and choose the platform that best aligns with your goals. Don't miss this practical, insight-packed hour designed to help you take your next step in the Reg CF ecosystem with confidence.SuperCrowd25, August 21st and 22nd: This two-day virtual event is an annual tradition but with big upgrades for 2025! We'll be streaming live across the web and on TV via e360tv. Apply for the Live Pitch here. VIPs get access to our better-than-in-person networking, including backstage passes, VIP networking and an exclusive VIP webinar! Get your VIP access for just $25. A select group of affordable sponsorship opportunities is still available. Learn more here.Community Event CalendarSuccessful Funding with Karl Dakin, Tuesdays at 10:00 AM ET - Click on Events.Devin Thorpe is featured in a free virtual masterclass series hosted by Irina Portnova titled Break Free, Elevate Your Money Mindset & Call In Overflow, focused on transforming your relationship with money through personal stories and practical insights. June 8-21, 2025.Join Dorian Dickinson, founder & CEO of FundingHope, for Startup.com's monthly crowdfunding workshop, where he'll dive into strategies for successfully raising capital through investment crowdfunding. June 24 at noon Eastern.Future Forward Summit: San Francisco, Wednesday, June 25 · 3:30 - 8:30 pm PDT.Regulated Investment Crowdfunding Summit 2025, Crowdfunding Professional Association, Washington DC, October 21-22, 2025.Impact Accelerator Summit is a live in-person event taking place in Austin, Texas, from October 23–25, 2025. This exclusive gathering brings together 100 heart-centered, conscious entrepreneurs generating $1M+ in revenue with 20–30 family offices and venture funds actively seeking to invest in world-changing businesses. Referred by Michael Dash, participants can expect an inspiring, high-impact experience focused on capital connection, growth, and global impact.Call for community action:Please show your support for a tax credit for investments made via Regulation Crowdfunding, benefiting both the investors and the small businesses that receive the investments. Learn more here.If you would like to submit an event for us to share with the 9,000+ changemakers, investors and entrepreneurs who are members of the SuperCrowd, click here.We use AI to help us write compelling recaps of each episode. Get full access to Superpowers for Good at www.superpowers4good.com/subscribe
In this episode, CancerNetwork® spoke with breast oncologists Heather McArthur, MD; Erika Hamilton, MD; Hope Rugo, MD; and Paolo Tarantino, MD, PhD, about advances in breast cancer. These developments included recent drug approvals and ongoing research for therapeutic approaches, particularly in the areas of antibody-drug conjugates (ADCs) and CDK4/6 inhibitors, based on presentations they gave at the 25th Annual International Congress on the Future of Breast Cancer (IBC) East in New York City. Initially, McArthur, Komen Distinguished Chair in Clinical Breast Cancer Research at the Harold C. Simmons Comprehensive Cancer Center, discussed immunotherapy use in high-risk triple-negative and HER2-positive disease, the evolving role of adjuvant CDK4/6 inhibition in HER2-negative breast cancer, and potentially transformative advancements in early breast cancer treatment. She highlighted the FDA approval for pembrolizumab (Keytruda) in early-stage triple-negative breast cancer, promising clinical trials in estrogen receptor (ER)–positive high-risk early-stage breast cancer, and data from an investigator-initiated trial to treat HER2-positive disease. Additionally, she highlighted an 8.5% improvement in pathological complete response with pembrolizumab added to immunotherapy in the phase 3 KEYNOTE-756 trial (NCT03725059), adding that a further event-free survival benefit may complicate the landscape for CDK4/6 inhibition based on lung and liver toxicities associated with the coadministration of these inhibitors with immunotherapy.1 McArthur expressed further excitement for ADC-based combinations for triple-negative disease, as well as in the high-risk residual disease setting. In addition, she highlighted potential advancements in de-escalation strategies and further considerations for ADCs in the HER2-positive and hormone receptor (HR)–positive spaces. Then, Hamilton, director of Breast Cancer and Gynecologic Cancer Research at the Sarah Cannon Research Institute, highlighted emerging therapies for early breast cancer, as well as her use of datopotamab deruxtecan-dlnk (dato-DXd; Datroway) and fam-trastuzumab deruxtecan-nxki (T-DXd; Enhertu) given their recent approvals in various breast cancer subtypes. She also touched upon challenges with respect to the implementation of new therapies for early breast cancer into clinical practice. She initially highlighted new data from the phase 3 VERITAC-2 trial (NCT05654623) presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.2 Specifically, findings showed that vepdegestrant, an oral proteolysis-targeting chimera (PROTAC), exhibited an efficacy advantage over fulvestrant (Faslodex) in patients with ESR1-mutant ER-positive, HER2-negative advanced or metastatic disease. Moreover, she highlighted data from the phase 3 DESTINY-Breast09 (NCT04784715) of T-DXd in various combinations for patients with HER2-positive metastatic breast cancer.3 Hamilton further highlighted her implementation of T-DXd into clinical practice, citing her use of the agent in patients with metastatic disease, including those with HER2-low and HER2-ultralow breast cancer. She further differentiated dato-DXd from T-DXd, suggesting that they were different classes of drugs due to their different targets: TROP2 vs HER2. She concluded by highlighting an unmet need regarding sustained benefit from endocrine therapy in HR-positive disease, as well as for ADC sequencing and mechanisms of resistance. Afterward, Rugo, division chief of Breast Medical Oncology, Women's Cancer Program Director, and professor in the Department of Medical Oncology and Therapeutics Research at City of Hope, discussed efficacy and safety considerations for CDK4/6 inhibitors in early breast cancer treatment. Specifically, she highlighted their high tolerability despite adverse effects and costs associated with their use. Rugo further touched upon a reduction of recurrence rates associated with CDK4/6 inhibition, although longer-term follow-up data were warranted to optimize the duration of therapy and elucidate survival outcomes. Finally, Tarantino, a research fellow at the Dana-Farber Institute, concluded by discussing sequencing strategies for ADCs, as well as which breast cancer settings or patient populations will experience the greatest impact with this treatment modality. Tarantino discussed his use of the “sandwich strategy,” where he switches the mechanism of action of treatment after using a TOPO1 ADC. Furthermore, Tarantino highlighted data from the DESTINY-Breast09 and phase 3 ASCENT-04 (NCT06100874) trials, which displayed the enhanced efficacy of 2 ADC combination therapies.4 He concluded by discussing future considerations for combining multiple ADCs. References 1. Cardoso F, O'Shaughnessy J, Liu Z, et al. Pembrolizumab and chemotherapy in high-risk, early-stage, ER+/HER2- breast cancer: a randomized phase 3 trial. Nat Med. 2025;31(2):442-448. doi:10.1038/s41591-024-03415-7 2. Hamilton E, De Laurentiis M, Jhaveri K, et al. Vepdegestrant, a PROTAC estrogen receptor (ER) degrader, vs fulvestrant in ER-positive/human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer: results of the global, randomized, phase 3 VERITAC-2 study. J Clin Oncol. 2025;43(suppl 17):LBA1000. doi:10.1200/JCO.2025.43.17_suppl.LBA1000 3. Tolaney S, Jiang Z, Zhang Q, et al. Trastuzumab deruxtecan (T-DXd) + pertuzumab (P) vs taxane + trastuzumab + pertuzumab (THP) for first-line (1L) treatment of patients (pts) with human epidermal growth factor receptor 2–positive (HER2+) advanced/metastatic breast cancer (a/mBC): interim results from DESTINY-Breast09. J Clin Oncol. 2025;43(suppl 17):LBA1008. 4. Tolaney SM, de Azambuja E, Kalinsky K, et al. Sacituzumab govitecan (SG) + pembrolizumab (pembro) vs chemotherapy (chemo) + pembro in previously untreated PD-L1–positive advanced triple-negative breast cancer (TNBC): Primary results from the randomized phase 3 ASCENT-04/KEYNOTE-D19 study. J Clin Oncol. 2025;43(suppl 17):LBA109. doi:10.1200/JCO.2025.43.17_suppl.LBA109
What if you've been told you need both radiation and anti-estrogen therapy after breast cancer surgery, but the evidence suggests one treatment might be enough?Many women over 60 with early-stage, estrogen-positive breast cancer find themselves navigating a confusing treatment landscape. Different specialists may recommend different therapies without clearly explaining whether all of them are necessary. Dr. Katie Deming draws on her 20 years as a board-certified radiation oncologist to break down decades of research that challenge the idea that more treatment is always better.Now practicing integrative oncology, she understands the science behind standard treatment protocols and also recognizes how these decisions affect real life. Her experience inside the conventional medical system gives her the insight to question current practices while still honoring the research that supports more personalized approaches.Dr. Katie addresses a critical issue many women face: being prescribed multiple treatments without knowing if both are needed. She walks you through key studies like CALGB 9343 and PRIME II in simple terms. She explains what recurrence rate may be acceptable for some women, especially when compared to the long-term side effects of hormone therapy. She also explores how radiation, while more intensive in the short term, might be a better option for those who prefer a time-limited treatment.Listen, learn, and you understand your options so you can make choices that align with your values and quality of life.Download - Navigating Breast Cancer After 60 guide: https://www.katiedeming.com/breast-cancer-guide/Save your spot for the next LIVE fasting call here: https://www.katiedeming.com/the-healing-power-of-fasting/ Don't Face Cancer Alone"The 6 Pillars of Healing Cancer" workshop series provides you valuable insights and strategies to support your healing journey - Click Here to Enroll MORE FROM KATIE DEMING M.D. Save your spot for the next LIVE fasting call here: https://www.katiedeming.com/the-healing-power-of-fasting/ Work with Dr. Katie: www.katiedeming.comEmail: INFO@KATIEDEMING.COM 6 Pillars of Healing Cancer Workshop Series - Click Here to Enroll Follow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.
Amanda Amin, MD, Janice Lyons, MD and Alberto Montero, MD, explore the evolution of breast cancer treatment. The discussion highlights how personalized care, clinical innovation and compassionate teamwork are transforming patient outcomes. Learn more about Amanda Amin, MD Learn more about Janice Lyons, MD Learn more about Alberto Montero, MD Learn more about the University Hospitals Research & Education Institute Follow Us on Social:
In this edition of The Naked Scientists: New DNA evidence helps free a British man after 38 years in prison. Also, Cambridge scientists push up breast cancer survival rates and cut side effects with a new treatment regimen. And, why the near and the far side of the Moon are world's apart in appearance: it's all down to temperature differences inside, scientists say... Like this podcast? Please help us by supporting the Naked Scientists
Dr. Anita Srinivasan, a surgical oncologist, discusses her journey in oncology, the challenges faced in safety net hospitals, and the importance of patient-centered care in surgical oncology. The discussion covers the pain comparison between mammograms and cosmetic treatments, the impact of fear on surgical choices, and the significance of advanced care planning and patient education in making informed decisions about breast cancer treatment.About Our Guest:Surgeon, Health Executive, Healthcare Operational Excellence and Profitability Leader | 20+ years as a surgeon, health executive, thought leader, innovator, and advocate for health equity and accessResources & Links:This episode was supported by the Patient Centered Outcomes Research Institute (PCORI) and features the PCORI research study here: https://pubmed.ncbi.nlm.nih.gov/30964385/ ‘Integrating Advance Care Planning Videos into Surgical Oncologic Care: A Randomized Clinical Trial'Chapter Codes00:00 The Pain of Mammograms vs. Cosmetic Treatments02:55 Dr. Anita Srinivasan's Journey in Oncology05:51 Understanding Safety Net Hospitals09:08 Challenges in Treating Advanced Breast Cancer12:02 Surgical Oncology: Approaches and Techniques15:08 The Importance of Patient-Centered Care17:56 Advanced Care Planning in Surgical Oncology21:07 The Role of Patient Education in Decision Making24:01 The Impact of Fear on Surgical Choices26:53 Future Directions in Surgical OncologyConnect with Us:Enjoyed this episode? Make sure to subscribe, rate, and review! Follow us on Instagram, Facebook, or Linkedin @mantacares and visit our website at mantacares.com for more episodes and updates.Listen Elsewhere: Website: https://mantacares.com/pages/podcast?srsltid=AfmBOopEP5GJ-Wd2nL-HYAInrwerIVhyJw67salKT-r9Qb_gadBvbHie YouTube: https://youtu.be/2SxvTqJht34?si=2U_98RfJJeWkTaT3 Spotify: https://open.spotify.com/episode/3TR1lFLtf6em5YyKtlWy2L?si=6ma-9g_wTIWTCLmHiHF_Aw Apple: https://podcasts.apple.com/us/podcast/navigating-cervical-cancer-screening-surgery-and/id1622669098?i=1000706666920 Disclaimer:All content and information provided in connection with Manta Cares is solely intended for informational and educational purposes only. This content and information is not intended to be a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.This episode was supported by an award from the Patient-Centered Outcomes Research Institute. Tags & Keywords:oncology, breast cancer, surgical oncology, patient care, mammograms, safety net hospitals, advanced care planning, patient education, mastectomy, lumpectomy
- Overview of Metastatic Breast Cancer - Current Standard of Care - New Treatment Approaches - Updates on Clinical Trials - How Clinical Research Increases Your Treatment Options - Biomarkers, Diagnostic Testing & Technologies: Why They Are Important in Informing Treatment Decisions for Metastatic Breast Cancer - Preventing & Managing Treatment Side Effects, Symptom, Discomfort & Pain - Communicating with Your Health Care Team about Quality-of-Life Concerns - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions & Discussion of OpenNotes - Quality of Life Concerns - Questions for Our Panel of Experts
Metastatic Breast Cancer CancerCare Connect Education Workshops
- Overview of Metastatic Breast Cancer - Current Standard of Care - New Treatment Approaches - Updates on Clinical Trials - How Clinical Research Increases Your Treatment Options - Biomarkers, Diagnostic Testing & Technologies: Why They Are Important in Informing Treatment Decisions for Metastatic Breast Cancer - Preventing & Managing Treatment Side Effects, Symptom, Discomfort & Pain - Communicating with Your Health Care Team about Quality-of-Life Concerns - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions & Discussion of OpenNotes - Quality of Life Concerns - Questions for Our Panel of Experts
- Overview of Metastatic Breast Cancer - Current Standard of Care - New Treatment Approaches - Updates on Clinical Trials - How Clinical Research Increases Your Treatment Options - Biomarkers, Diagnostic Testing & Technologies: Why They Are Important in Informing Treatment Decisions for Metastatic Breast Cancer - Preventing & Managing Treatment Side Effects, Symptom, Discomfort & Pain - Communicating with Your Health Care Team about Quality-of-Life Concerns - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions & Discussion of OpenNotes - Quality of Life Concerns - Questions for Our Panel of Experts
Breast cancer survivors are living longer than ever, thanks to research and medical advances, but new studies suggest that some treatments may come with a hidden cost: accelerated aging. A recent study, titled “Accelerated aging associated with cancer characteristics and treatments among breast cancer survivors,” published in Aging (Aging-US), reveals that breast cancer and its treatments may speed up biological aging, with effects lasting up to a decade post-diagnosis. Breast Cancer and Aging Breast cancer is one of the most common cancers among women worldwide. Medical advancements have dramatically improved survival rates, making it one of the most treatable forms of cancer. Yet, many survivors report lasting symptoms like fatigue, memory issues, and reduced vitality that resemble accelerated aging. This pattern has led scientists to investigate whether treatments for breast cancer might be contributing to biological age acceleration. Full blog - https://aging-us.org/2025/04/breast-cancer-treatments-hidden-impact-accelerated-aging-among-survivors/ Paper DOI - https://doi.org/10.18632/aging.206218 Corresponding author - Xiao-Ou Shu - xiao-ou.shu@vumc.org Video short - https://www.youtube.com/watch?v=cfuyzVyDeHY Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206218 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, accelerated aging, PhenoAge, breast cancer, survivors Visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
- Overview of the Diagnosis & Treatment of Breast Cancer in Men - Detection of Breast Cancer in Men – Mammogram, Ultrasound, Biopsy - Grading & Staging of Breast Cancer - Understanding the Treatment of Breast Cancer in Men – Surgery, Radiation, Immunotherapy, Targeted Treatments - Definition of Genetics & Genomics of Breast Cancer in Men - Tools that Help Predict the Risk of Breast Cancer Recurrence in Men - How Genomic Testing Informs Breast Cancer Treatment Planning for Men with Breast Cancer - Critical Role of Genetic & Genomic Testing Throughout All Stages of Breast Cancer in Men - The Value of Early Testing to Inform Treatment Choices - Their Role in Selecting Your Best Cancer Treatment - The Role of the Pathologist - The Difference Between Inherited & Acquired or Sporadic Gene Mutations - Understanding the Types of Gene Mutations - Genetic Testing, Including Testing for BRCA Mutations - Preventing & Managing Treatment Side Effects & Long Term Effects of Breast Cancer Treatment in Men - Follow-Up Care - Survivorship Care Plan - Nutrition & Hydration Concerns & Tips - Support for Men Living With & Surviving Breast Cancer - Questions for Our Panel of Experts
- Overview of the Diagnosis & Treatment of Breast Cancer in Men - Detection of Breast Cancer in Men – Mammogram, Ultrasound, Biopsy - Grading & Staging of Breast Cancer - Understanding the Treatment of Breast Cancer in Men – Surgery, Radiation, Immunotherapy, Targeted Treatments - Definition of Genetics & Genomics of Breast Cancer in Men - Tools that Help Predict the Risk of Breast Cancer Recurrence in Men - How Genomic Testing Informs Breast Cancer Treatment Planning for Men with Breast Cancer - Critical Role of Genetic & Genomic Testing Throughout All Stages of Breast Cancer in Men - The Value of Early Testing to Inform Treatment Choices - Their Role in Selecting Your Best Cancer Treatment - The Role of the Pathologist - The Difference Between Inherited & Acquired or Sporadic Gene Mutations - Understanding the Types of Gene Mutations - Genetic Testing, Including Testing for BRCA Mutations - Preventing & Managing Treatment Side Effects & Long Term Effects of Breast Cancer Treatment in Men - Follow-Up Care - Survivorship Care Plan - Nutrition & Hydration Concerns & Tips - Support for Men Living With & Surviving Breast Cancer - Questions for Our Panel of Experts
Dr Kaklamani discusses the mechanism of action of inavolisib, the importance of the addition of this agent to the HR-positive metastatic breast cancer treatment paradigm, and considerations for early biomarker testing in patients with breast cancer.
About 10% to 15% of breast cancers are triple-negative. This means they don't have receptors for the hormones estrogen or progesterone, and don't have too many HER2 proteins. So, hormonal therapy medicines and medicines that target the HER2 protein aren't effective against triple-negative breast cancer. Chemotherapy and immunotherapy are commonly used to treat triple-negative disease. But scientists are working diligently to develop new treatments that are more precise and targeted. Triple-negative breast cancer expert Dr. Lisa Carey explains the latest research. Listen to the episode to hear Dr. Carey discuss: the two main areas of research on triple-negative breast cancer what antibody-drug conjugates are and their potential for treating triple-negative disease the benefits of combining antibody-drug conjugates with immunotherapy the features of triple-negative breast cancer that make researchers think a vaccine for it is possible
“This is what totally drives the treatment decisions, and that's why having that pathology report when the nurse is educating the patient is so important, because you can say, well, you have this kind of breast cancer, and this kind of breast cancer is generally treated this way,” Suzanne Mahon, DNS, RN, AOCN®, AGN-BC, FAAN, professor emeritus at Saint Louis University in Missouri, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about what oncology nurses need to know about breast cancer treatment. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 1.0 contact hours (including 15 minutes of pharmacotherapeutic content) of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by February 14, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to breast cancer treatment considerations. Episode Notes Complete this evaluation for free NCPD. Previous ONS Podcast™ site-specific episodes: ONS Voice articles: Episode 348: Breast Cancer Diagnostic Considerations for Nurses Episode 345: Breast Cancer Screening, Detection, and Disparities ONS Voice articles: An Oncology Nurse's Guide to Cascade Testing Breast Cancer Prevention, Screening, Diagnosis, Treatment, Side Effect, and Survivorship Considerations Learn How to Read a Germline Genomic Testing Report Learn How to Read a Somatic Biomarker Testing Report Sexual Considerations for Patients With Cancer ONS books: Breast Care Certification Review (second edition) Guide to Breast Care for Oncology Nurses ONS courses: Breast Cancer Bundle Breast Cancer: Treatment and Symptom Management ONS Biomarker Database results for breast cancer ONS Next-Generation Sequencing Sample Report ONS Learning Libraries: Breast Cancer Genomics and Precision Oncology American Cancer Society: Breast Cancer Facts and Figures Your Breast Pathology Report: Breast Cancer National Comprehensive Cancer Network National Cancer Institute Breast Cancer—Patient Version To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “Local treatment is typically going to consider some kind of surgery with or without radiation, depending on the surgery and the extent of the breast cancer. All women are going to have, and today when you use the word women, individuals assigned female at birth, they are the vast majority of individuals being treated for breast cancer, but for individuals assigned male at birth, there's not near as much research, but generally their treatment is very similar. So that's something to kind of keep in the back of your mind.” TS 2:39 “This is very confusing for patients because they're like, ‘Well, my friend at church had this and why am I getting this and why are they getting something different?' And that is because of the pathology report. So taking that time to explain that with a pathology, I think is really important.” TS 8:31 “When they see the breast surgeon, all individuals are going to have some kind of axillary evaluation. Now, hopefully it's going to be a sentinel lymph node. So they're going to, at the time of surgery, put a tracer and, you know, they're going to take out maybe one, two, three lymph nodes and hopefully, you know, there is not a lot of disease there. And if that's the case, they're kind of done with that. So the sentinel lymph node evaluation, it's really more to stage and provide that information, but it kind of sets the stage a lot of times for the other treatments selections. And I think people need to realize that this is important. This is a very important procedure.” TS 15:31 “Years ago, when women had a breast mass, they went to the OR and it was biopsied in a frozen section and if it was positive, they had a mastectomy. So women would wake up and they'd be feeling their chest because they're like, ‘What happened here?' And that is not great care. It doesn't give that woman any autonomy, but it was the best that could be done at that point. Now, with the diagnostic where we can do a needle biopsy, they can kind of stop and take a timeout and we can kind of clinically stage that.” TS 17:04 “For women that really desire breast-conserving therapy, they can anticipate that postoperatively at some point, they're going to have treatment to the entire breast, we typically call whole breast radiation, and then they may have a boost. Now, in many, many probably cases, that's going to be over five to six weeks, Monday through Friday. So the treatment itself doesn't take but a couple of minutes, but you have to get to the facility. And even though we streamline check-in processes and whatnot, you have to get undressed, you have to get positioned on the table. So it is a commitment, and it can be disruptive.” TS 24:49 “The hormone-blocking agents are going to be the cornerstone of all those treatments for anyone who has hormone receptor–positive breast cancer. So they are going to take these agents and as you said, they're probably going to take them for 5–10 years. It's quite the journey.” TS 32:33 “I think you need to be mindful that if someone has had germline testing and they've tested positive, they are not only worried about themselves, and they are worried about the rest of their family. That is a big deal. And even though I'll hear mothers say, ‘I feel so guilty, now my daughter has this,' now, I've never heard a daughter come and say, ‘Gosh, I wish my mom hadn't had me because of this.' There's a lot of feeling and emotion that goes on with that, and realize that those individuals are probably going to have fairly complicated management that goes over and above their breast cancer.” TS 41:50
The imPROVE study aims to bridge the gap in patient-reported outcomes (PRO) data for Black women with breast cancer by enhancing engagement with tailored electronic PROs (ePROs) and partnering with community leaders to address barriers and ensure accessibility and relevance in community cancer care settings. In this episode, CANCER BUZZ speaks with Manraj Kaur, PhD, investigator and lead faculty for research and innovation at Patient-Reported Outcomes, Value, and Experience (PROVE) center at Mass General Brigham and Andrea Pusic, MD, chief of division of plastic and reconstructive surgery, director of PROVE center at Mass General Brigham, and professor of surgery at Harvard Medical School about the imPROVE study's efforts to enhance Black women's engagement in ePROs in breast cancer treatment. Dr. Kaur sheds light on strategies to improve technology accessibility for Black women in their cancer care center by providing iPads and refined usability features on the imPROVE app. Dr. Pusic highlights imPROVE implementation results at five community cancer centers, including utilizing local champions and equitable access to resources. “When we make sure Black women are included, we gain a more accurate picture of health, we can design better care, and then we take a real step towards closing the health equity gap.” – Manraj Kaur “The imPROVE study is all about increasing accessibility of patient-reported outcome measurements to Black breast cancer patients receiving care in community cancer centers.” – Andrea Pusic Manraj Kaur, PhD Investigator, Lead Faculty for Research and Innovation Patient-Reported Outcomes Value Experience (PROVE) Center Brigham and Women's Hospital Boston, MA Andrea Pusic, MD Chief of Division of Plastic and Reconstructive Surgery Director, PROVE Center Brigham and Women's Hospital Professor of Surgery Harvard Medical School Boston, MA Resources: ACCC imPROVE Study Blog - https://www.accc-cancer.org/acccbuzz/blog-post-template/accc-buzz/2024/06/18/the-power-of-patient-reported-outcome-measures-to-community-cancer-centers? Harvard/BWH PROVE Center - https://prove.bwh.harvard.edu/current_project/improve-breast-cancer-care/
This week on The Genetics Podcast, Patrick is joined by Versha Pleasant, Clinical Assistant Professor in the Department of Obstetrics and Gynecology, University of Michigan and Director of the Cancer Genetics and Breast Health Clinic at Von Voigtlander Women's Hospital. They discuss ongoing disparities in healthcare, in particular why black women in the US have a 40% higher chance of dying from breast cancer than white women, the impact of the US Educate Act on equality, diversity and inclusion education, and much more. 00:00:00 – Intro to The Genetics Podcast 00:01:52 – Welcome to Versha 00:03:22 – How black women have a 40% higher chance of mortality from breast cancer than white women, and the biggest drivers of this disparity 00:07:09 – Multifaceted approaches to addressing disparities 00:09:10 – Racial health duplicity and increasing access to genetic testing and mammography for black women 00:13:51 – The challenges of using precision medicine to stratify risk in black communities and historical harms in US medical research 00:14:29 – How to design for inclusive studies that effectively represent communities of colour 00:16:13 – Considering universal genetic testing and counseling for black women 00:21:24 – The logistics of making universal testing a reality, and the importance of community education and trust building 00:27:18 – What Versha is focused on next and the big topics she wants to tackle 00:33:24 – The role of community education and diversifying modes of communication for knowledge sharing 00:34:36 – Versha's perspectives on the US Educate Act and the impact it could have on what doctors of the future are taught 00:40:52 – Versha's advice to people who would like to pursue a similar career in medicine 00:43:28 – Where Patrick sees genetics evolving in the next ten years and his vision for the future of The Genetics Podcast 00:47:39 – Closing remarks Find out more Universal Genetic Counseling and Testing for Black Women: A Risk-Stratified Approach to Addressing Breast Cancer Disparities: https://www.clinical-breast-cancer.com/article/S1526-8209(24)00338-0/fulltext Please consider rating and reviewing us on your chosen podcast listening platform! https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
Today, we dive into a thought-provoking discussion with Dr. Jennifer Simmons, a breast cancer surgeon turned functional medicine oncologist, who is redefining breast cancer diagnosis, treatment, and screening. Use Jenn's code: Drjenn20 for 20% of the Auria test. What We Discuss: Critique of Mammograms and Below-Average Efficacy ... 03:15 Canadian Breast Cancer Screening Trial Findings ... 06:50 Concerns with Overdiagnosis in Mammograms ... 08:25 Consequences of Unnecessary Breast Cancer Treatments ... 11:40 Absence of Predictive Tests for Cancer Aggressiveness ... 15:10 Debunking the Myth of Early Detection's Efficacy ... 18:00 Dense Breast Tissue and Mammogram Limitations ... 21:30 Risks Associated with Mammogram Radiation ... 24:10 Importance of Lymphatic System Health ... 29:00 Alternative Approaches to Monitoring Breast Health ... 32:20 Holistic Benefits of Rebounding, Dry Skin Brushing ... 35:45 Criticism of Restrictive Bras and Advice on Usage ... 38:10 Bioidentical Hormone Replacement Therapy (HRT) Insights ... 41:20 Misconceptions About Estrogen and Breast Cancer ... 45:05 Introduction to the Mitolux Device ... 51:50 Dietary and Physical Recommendations for Optimal Health ... 54:20 History and Long-term Impact of Breast Health ... 1:09:05 Pharmaceutical Dependencies and Lifestyle Impact ... 1:12:20 Arguments Against Over-treatment of DCIS ... 1:15:30 Innovative Breast Cancer Screening Tests: AURIA and QT Scan ... 1:18:50 Challenges with Current Breast Cancer Treatments ... 1:22:10 Ethical Considerations in Breast Cancer Treatment ... 1:25:45 Made Possible By Our Amazing Sponsor: SiPhox - SiPhox Health offers at-home blood testing solutions, providing custom supplements based on your personalized blood work. Visit http://SiPhoxhealth.com/nat and use code LONGEVITY to save on your test. Manukora - Looking to boost your immunity and gut health with nature's finest? Manukora Honey, sourced from New Zealand, brings you high-quality honey rich in health benefits. Visit this link http://manukora.pxf.io/kO0rJN to enjoy a special discount with the code LONGEVITY. Wizard Sciences - Ready to upgrade your brain game? Unlock your cognitive potential with Neural Rx. Use code NAT15 at checkout to get 15% off your purchase. Don't wait—start the year with a sharper, more focused mind. Visit Wizardsciences.com Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
CME credits: 1.50 Valid until: 30-12-2025 Claim your CME credit at https://reachmd.com/programs/cme/expert-viewpoint-optimizing-breast-cancer-treatment/29832/ Treatment decision-making in breast cancer is complex and incorporates several factors including disease- and patient-related characteristics. The NCCN Clinical Practice Guidelines are regularly updated to provide the most accurate recommendations based on recent scientific evidence and drug approvals. This activity has been designed to review the current NCCN guidelines and the supporting data and explore best practices for selecting therapy based on these recommendations. Explore guideline-based strategies and clinical data to optimize guideline-adherent care for patients with CLL/SLL and MCL.
Can we prevent breast cancer before it even starts? While treatments have made great strides in curing and slowing cancer, researchers are now focusing on strengthening the immune system to stop cancer in its tracks. In this episode, Dr. Robert Vonderheide, director of the Abramson Cancer Center at the University of Pennsylvania, shares his groundbreaking work on how the immune system interacts with cancer. As a leader in cancer immunology, Dr. Vonderheide explores how boosting our body's natural defenses could lead to new ways to prevent, treat, and even cure breast cancer.
Solutions often begin with a conversation. When faced with the task of planning your surgery, it is the goal of the DiepCJourney podcast to provide a pathway to workable solutions for those affected by breast cancer. My guest is Dr. Andrew Elkwood, an international expert in advanced reconstruction and a highly skilled microsurgeon. Dr. Elkwood is the founder of The Plastic Surgery Center and Institute for Advanced Reconstruction (IFAR) in New Jersey. You can also visit www.advancedreconstruction.com or call 954-218-5137 to schedule a consultation with a surgeon on these advanced and specialty conditions. The surgeons in the IFAR network perform breast reconstruction surgery due to loss of breast after mastectomy from breast cancer. They also perform the following surgery addressing conditions that arise due to breast cancer treatment, many of which are nerve related. · Neuropathy · post mastectomy pain syndrome · lymphedema surgery · radiation-induced brachial plexopathy (numbness, tingling, weakness in the shoulder and/or arm Watch the interview on YouTube: Pathways to Care Due to Secondary Issues from Breast Cancer Treatment Follow IFAR on Social Media: Instagram Facebook YouTube
Each year about 300,000 women are diagnosed with breast cancer. Many of those will be put on a medication to suppress estrogen. While this is an important strategy for treating these cancers, most clinicians are not adequately protecting bones from the most dangerous side effect—osteoporosis and fractures. Key Takeaways To Tune In For: (00:25) - Importance of Bone Health in Breast Cancer Treatment (02:51) - Effects of Estrogen on Bone Health (03:37) - Bone Density Testing is Essential (05:55) - Medication and Natural Approaches to Combat Bone Loss (07:57) - Exercise and Lifestyle Changes to Prevent Fractures Resources talked about in this episode Book: Fracture-Proof Your Bones Products: NBI Bone Support Dietary Supplements Articles: Comprehensive List of Medications that Cause Osteoporosis 3-Steps to Eating Healthy for Life
In our exclusive interview, Dr Kalinsky discussed his top takeaways from the 2024 ASCO Annual Meeting and 2024 ESMO Congress, as well as where he sees the field of breast cancer headed in the future.
In this episode (part 2 of 2), Dr. Diane Reidy-Lagunes speaks with a team of MSK experts to explore the complexities of breast cancer treatment and life afterwards. Breast medical oncologist Dr. Julia Brockway-Marchello and nurse Jenna Galinsky explain chemotherapy and hormone therapy, their potential side effects, and ways they can be alleviated. Nurse Adriana Olivo discusses how survivors can cope with emotional challenges, like the fear cancer will come back. Breast cancer patients and survivors offer advice on asking for support while navigating life during and after cancer treatment. Listen to episode 52 "Breast Cancer Treatment Part 1: Surgery, Radiation and Reconstruction" Listen to episode 39 "How to Manage Side Effects During Cancer Treatment: Fatigue, Hair Loss, Skin Care and More" Listen to episode 12 "A Woman's Guide to Sex and Cancer" Episode Chapters:1:44 - Why use some treatments over others?2:55 - Types of breast cancers & their treatments4:50 - Patient testimonial on self-advocacy6:02 - Length of treatment & why it can change7:38 - Quality of life advice during treatment9:10 - Mitigating chemotherapy side effects9:57 - Maintaining sexual health during treatment10:46 - When is taking estrogen a bad idea?13:07 - Quality of life concerns & when to switch meds16:16 - Mitigating hormone therapy side effects17:32 - Patient testimonial on finishing treatment18:22 - Managing fear & life after treatment19:34 - Mitigating long-term side effects of treatment21:24 - Patient testimonial on fear of recurrence22:49 - Why scanning for recurrence isn't recommended26:25 - The reason for all this: live your life!See omnystudio.com/listener for privacy information.
How does a mother navigate a healthcare system that often fails to see her pain? Courtney Clark's struggle with medical dismissal and racial bias highlights a critical gap in healthcare. At 34, while nursing her daughter, she discovered a lump only to be dismissed by her doctor. Her story underscores the importance of advocating for oneself and seeking thorough medical attention. Key Questions Answered 1. What did Courtney feel was the doctor's reaction to her concerns about the lump? 2. How did Courtney feel about the care she received from the doctor based on her race? 3. What was Courtney's life situation when she first discovered the lump? 4. What type of cancer was Courtney eventually diagnosed with? 5. What was Courtney's experience with her healthcare during pregnancy related to her breast concerns? 6. What does Courtney believe doctors should do when patients express concerns about potential breast cancer symptoms? Timestamped Overview 00:00 Podcast on breast health from The Rose. 04:49 Finding a doctor who understands is crucial. 06:58 Trust intuition and seek multiple medical opinions. 09:51 Importance of support and definitive diagnosis in responsibility. Support The Rose HERE. Subscribe to Let's Talk About Your Breasts on Apple Podcasts, Spotify, iHeart, and wherever you get your podcasts.See omnystudio.com/listener for privacy information.
Interview with surgeon Scott Albert, MD
For Breast Cancer Awareness Month, we're joined by Dr. Patrick Borgen, Chair, Surgery and Director of the Breast Cancer Program at Maimonides Medical Center. After working at Memorial Sloan Kettering, Dr. Borgen came to Maimonides to work with patients from under-resourced communities. Maimonides Health is Brooklyn's largest healthcare system, serving over 320,000 patients each year through the system's three hospitals, with 7,000+ employees, 1,800+ physicians, and more than 80 community-based practices and outpatient centers. Patients with advanced breast cancer treated at Maimonides lived longer than the national average. For more, visit maimo.org.
Today's guest is Heather DeKeyser, LMFT, CST, a Licensed Marriage and Family Therapist and Certified Sex Therapist in Colorado with a passion for helping individuals and couples navigate the complexities of relationships and sexual health. She co-founded and is the Clinical Director of a group therapy practice called Dalliance Sexual Wellness Collective. She's also a survivor of triple negative breast cancer.In this episode we talk about navigating treatment, the emotional aftermath that happens after active treatment, how important therapy and mental health are during and after cancer, finding a new definition of sex and intimacy after breast cancer, and so much more!This is Part 1 of our series on sexual wellness. Today is Heather's personal story. We will have Part 2 next week with more of a deep dive into redefining sexual health and wellness. So stay tuned!Heather's website https://www.dalliancesexualwellness.com/. She offers a free 20 minute consultation. Her email is heather@dalliancesexualwellness.comYou can subscribe to Heather's free monthly newsletter at https://www.dalliancesexualwellness.com/pleasure-perspectives-newsletter-archiveShe's on Facebook at https://www.facebook.com/DallianceSWCIG https://www.instagram.com/dalliance_swc/Let me know your biggest takeaways! I want to hear from you! You can message me on Instagram at https://www.instagram.com/melissagrosboll/, email me at drmelissagrosboll@gmail.com, or text me at 720-201-4292
I'm thrilled to introduce Dr. Elizabeth Comen, a leading breast oncologist and USA Today bestselling author of “All In Her Head.” Dr. Comen is passionate about empowering patients to advocate for themselves throughout their breast cancer journey. In this episode, we discuss the complexities of breast cancer care, and how to talk to your doctor during breast cancer treatment to get the care you need and deserve. Join us as Dr. Comen shares valuable insights to help you navigate your experience and ensure the best possible outcomes for your health.
An assessment of progress with antibody-drug conjugates (ADCs) for the treatment of HER2-dependent metastatic breast cancer was given at the 2024 Chinese Society of Clinical Oncology (CSCO) Annual Meeting. The President-Elect of the European Society for Medical Oncology (ESMO), Giuseppe Curigliano, MD, PhD, Director of the Early Drug Development for Innovative Therapies Division at the European Institute of Oncology and the University of Milano in Italy, told Oncology Times reporter Peter Goodwin about the broadening scope of ADCs in breast cancer and his reasons for encouraging ESMO and CSCO to continue to expand their co-operation.
A number of breast cancer treatments, including chemotherapy and some targeted therapy medicines, like Herceptin (trastuzumab), can cause oral side effects, including mouth sores, dry mouth and infections. Dr. Sollecito explains why these side effects happen and how they're treated. Listen to the episode to hear Dr. Sollecito explain: why it's a good idea to see a dentist before starting chemotherapy the type of dental check-up schedule someone receiving breast cancer treatment should consider what to do if you develop a cavity or need a root canal during treatment
Your DNA plays a large part in how you react to medications and, ultimately, how your body reacts during treatment and beyond. Today, host Sarah talks with Samantha Socco, Medical Science Liaison at GeneSight, about pharmacogenomics - and what all breast cancer patients should know.
In this episode, we explore the fascinating world of deuterium with Dr. Petra, examining its role in our health. Dr. Petra shares her clinical experiences using deuterium depletion strategies to address cancer, autoimmune conditions, obesity, and metabolic disorders. We'll uncover practical, everyday tips for improving mitochondrial health and how simple changes in diet and lifestyle can make a significant difference. Tune in to discover how deuterium might impact your health and gain insights into actionable steps you can take today. no Timestamps: 03:49 - Petra's Background and Journey 05:16 - Deuterium's Role in Cancer Treatment 08:06 - Exploring NAD IV Therapy 09:52 - Strategies for Breast Cancer Treatment 11:32 - Therapeutic Ketosis Explained 12:27 - How Reducing Water Intake Affects Health 14:01 - Deuterium Levels and Related Health Issues 14:57 - Finding Your Optimal Deuterium Levels & Testing 17:17 - The Benefits of Sunlight Exposure 21:57 - Circadian Rhythms and Breathwork Techniques 24:06 - The Impact of Mouth Taping and Exercise 26:54 - Why Low-Carb Dieting Matters 30:15 - The Concept of Seasonal Eating 33:20 - Deuterium's Impact on Diabetes and Obesity 37:14 - Dining Out: Avoiding Seed Oils 39:45 - The Connection Between Glyphosate and Deuterium 41:35 - Insights from Hydration Studies 45:21 - Deuterium Depletion Programs: What You Need to Know 51:26 - How Deuterium Affects Fertility and Pregnancy Show Links: Sayan Chaga Breathe by James Nester Seed Oil Scout Sponsored By: Viva Rays Go to vivarays.com & use code: YOGI to save 15% Upgraded Formulas Use code YOGI for 10% off at www.upgradedformulas.com/ Check Out Dr. Petra: Website This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional! Click here to get all my free guides and product recommendations to get started on your journey! Check out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) Sign up for my newsletter to get special offers in the future!
What does it mean when two up and coming, globally successful business people face a life threatening diagnosis? Jeff and Janette Marx share their experience when Janette was diagnosed and treated for breast cancer. Jeff emphasizes the importance of positivity and being a strong pillar. He highlights collaboration with family and clear work communication. Janette discusses Jeff's balance of support and responsibilities. Both stress honest communication and personal boundaries. Cancer impacts the whole family and their candid stories convey the different dimensions and key elements needed to survive together. Please share this episode with family and friends, and consider making a donation at therose.org. It could save the life of an uninsured woman. Key Questions Answered 1.) What was Jeff's reaction to Janette's breast cancer diagnosis? 2.) How did Jeff support Janette throughout her breast cancer experience? 3.) How did Jeff battle his personal fears during Janette's breast cancer experience? 4.) How did Jeff balance being a caretaker and having a career? 5.) What's Jeff's message for anyone who's supporting their spouse through a cancer diagnosis? Timestamped Overview 00:00 Upon her return, I sensed trouble immediately. 04:30 Fear of losing her, but hopeful and supportive. 08:30 Fears and support during post-surgery recovery. 11:38 Maintain communication, share responsibilities, and offer support. 15:33 Caring for wife, adjusting work schedule. 18:07 Doctors provided vital support post-surgery. Partnered effectively. 20:18 "Be positive and bring strength to others."See omnystudio.com/listener for privacy information.
Mike is riding so others can live. Today Mike Hazelrigs and his fiancé Kathy Stevens share what it means to face metastatic breast cancer after years of treatment. Theirs is a true love story amid real-life adversity and hardships. Mike is taking their story to a new level as he rides in the historic Hoka Hey Motorcycle Challenge TM, a 10,000-mile trek, crisscrossing the United States and Canada, in honor of Kathy and to raise funds for the women of The Rose. Also, during this episode, Kathy talks about the hidden costs of cancer and how understanding one's insurance claims and explanation of benefits could reveal charges that simply aren't real. With the extraordinal costs of healthcare and particularly cancer treatment, additional, unjustifiable charges are one more issue a survivor shouldn't have to worry about but must. She offers valuable tips and ways to ensure every charge is correct. To easily support Mike, visit The Rose's website. Please share this episode with family and friends, and consider making a donation at therose.org. It could save the life of an uninsured woman. Key Questions Answered 1.) Why is Mike Hazelrigs riding 10,000 miles across the United States? 2.) What precautions should women take when undergoing radiation treatment for breast cancer? 3.) What practical tips are helpful during the recovery phase after breast cancer surgery? 4.) What kind of support can caregivers expect and what should they keep in mind? 5.). How can patients avoid unexpected out-of-network charges during their treatment? Timestamped Overview 00:00 Couple raising money for breast cancer awareness 05:08 Caregivers must prioritize self-care and support. 08:06 Delay invoice payments, verify charges on EOBs. 11:39 Support cancer patients and caregivers without hesitation. 13:12 Podcast on breast health and support organization.See omnystudio.com/listener for privacy information.
Did you know 1 in 8 women will get breast cancer in their lifetime? Join Lauren Bright Pacheco for a special episode from the 2024 ASCO Annual Meeting in Chicago, where she dives into the best collaborative approach to breast cancer diagnoses and care. Medical oncologist, Dr. Nan Chen, and breast cancer surgeon, Dr. Sarah Shubeck share how their teamwork benefits breast cancer treatment.See omnystudio.com/listener for privacy information.
In this episode, host Kathe Kline and guest Barbara delve into crucial aspects of end-of-life planning and the importance of safety for older adults. They discuss bathroom accessibility improvements, emphasizing the need for thoughtful renovations to prevent falls. Barbara shares her personal journey as a breast cancer patient, highlighting her experiences with radiation therapy and the significance of humor during such challenges. They stress the necessity of legal preparations like wills, medical directives, and trusts to ease future burdens on loved ones, and offer practical advice on managing personal belongings and organizing essential information for emergencies. The conversation underscores the emotional and practical aspects of aging and the importance of embracing comprehensive planning for retirement and beyond.
Tushar Pandey is a distinguished expert in the Life Sciences industry, currently making significant strides at SimBioSys with his innovative approach to healthcare technology. His contributions have been pivotal in advancing medical solutions and improving patient outcomes. In this episode of the Life Science Success Podcast, host Don interviews Tushar Pandey, CEO and Co-founder of SymBioSys, an innovative company reshaping precision cancer care. Tushar shares his intriguing journey from Uganda to the United States, his transition from engineering to healthcare, and the personal experiences that sparked his passion for precision medicine. The discussion highlights SymBioSys' groundbreaking work in creating digital, cost-effective diagnostics to reduce uncertainty in cancer treatment. They explore the importance of addressing diversity in medical models, harnessing the power of AI, and solving challenges in drug development and patient care. Agendas like the company's comprehensive platform for early-stage breast cancer get a deep dive, showcasing how they bridge imaging, genomics, and patient-centered care for improved outcomes. This conversation is a rich mix of personal narrative, professional insights, and forward-thinking solutions in life sciences. 00:00 Introduction to Life Science Success Podcast 00:34 Sponsor Message from D3 Digital Media Marketing 01:25 Guest Introduction: Tushar Pandey 02:27 Tushar's Background and Journey 04:30 Early Career and Transition to Healthcare 06:01 Strata Decision Technology and Cost Optimization 07:57 Personal Impact of Cancer and Shift to Precision Medicine 08:54 Founding Symbiosis and Mission 11:04 Challenges and Innovations in Cancer Treatment 12:21 Symbiosis' Approach to Precision Medicine 14:04 Scientific and Emotional Theses 15:34 Digital Solutions and Global Scale 15:58 Breast Cancer Treatment and FDA Approval 18:05 Supporting Drug Developers and Dosing Regimens 19:30 Digital Orientation and Multi-Omics Data 20:24 Identifying Critical Data in Precision Medicine 20:50 Incorporating Diversity in Medical Models 23:49 Innovative Projects in Digital Health 25:07 The Role of Imaging in Precision Medicine 31:08 Challenges in Life Sciences and Overcoming Them 33:31 Leadership and Inspiration in Precision Medicine 37:28 Concerns and Future Directions in Healthcare 42:02 Conclusion and Final Thoughts
In this episode (part 1 of 2), Dr. Diane Reidy-Lagunes speaks with a team of MSK experts to demystify three breast cancer treatment options: surgery, radiation, and reconstruction. Breast surgeon Dr. Tracy-Ann Moo explains the difference between a lumpectomy and a mastectomy, and why one isn't always better than the other. Radiation oncologist Dr. Michael Bernstein discusses the role of radiation therapy in the treatment of breast cancer. Plastic and reconstructive surgeon Dr. Michelle Coriddi describes various breast reconstruction and preservation techniques, which can help patients maintain a positive body image after treatment. Subscribe to Cancer Straight Talk to be notified when Part 2 airs, covering chemotherapy, hormone therapy and survivorship for people with breast cancer. Episode Highlights:1:27 - Surgery7:36 - Radiation15:10 - Reconstruction See omnystudio.com/listener for privacy information.
When you emerge from breast cancer treatment, it's not uncommon to feel out of alignment with life. Something about facing our mortality causes us to reevaluate things. So how do you realign yourself? How do you take the steps towards the future version of your life? In this episode, I'll give you four simple, key steps to help you move your life into alignment with your desires. Check it out now and think about your next decision. Referred to in this episode: The Four Pillars of Breast Cancer Recovery Becoming You 2.0 Cancer Patients vs. Cancer Survivors – Jubilee Media Food Healed me Summit Follow me on Social Media: Facebook Instagram Pinterest YouTube
Last week, we saw some research regarding how a popular tool used to plan breast cancer treatment may be misguiding therapy for Black women, as well as an update on when we can expect to see a new cancer vaccine be readily available for patients. And on the FDA front, we'll discuss a priority review for Enhertu for patients with HER2-positive solid cancers, as well as a fast track designation for a new drug duo in the lung cancer space. Cancer Vaccine Likely ‘Several Years' Away From Wide Availability ELI-002 is a vaccine being investigated for the treatment of patients with KRAS-mutant pancreatic or colorectal cancers. While cancer vaccines have been in the headlines a lot in recent months, this one, at least, is still a ways away from being readily available for patients across the United States. Findings from a phase 1 trial showed that the vaccine could be beneficial for this patient population, and now, a phase 2 trial recently started that will evaluate the efficacy of an injection version of ELI-002, compared to observation. The first patient was dosed in the trial in January 2024, so it could still be several more years until the drug is available, Dr. Christopher Haqq, chief medical officer and vice president, head of research and development at Elicio Therapeutics, said in an interview with CURE®. “We'll be talking to the regulators like the US Food and Drug Administration and others around the world to align on the data that we'll need to provide for a marketing application. And so, we haven't had that input yet. So I can't give an exact answer for you (on when the vaccine will be commercially available). But we'll work as fast as possible. It's even possible that the type of evidence that we gather in this randomized study could serve that purpose. But we won't know until we have further discussion,” he said. Test May Be ‘Misguiding' Breast Cancer Treatment for Black Women A recent study showed that the 21-gene breast recurrence score may lead clinicians away from prescribing chemotherapy to Black women who may benefit from the treatment. The 21-gene breast recurrence score is the standard test to help guide treatment decisions for patients with estrogen receptor-positive (also known as ER-positive) disease. Most patients with ER-positive cancer undergo hormone therapy, but the outcomes for this test may help decide if a patient would benefit from additional chemotherapy, too. Now, findings from a recent study discovered that Black women — and younger Black women, in particular — may be missing out on chemotherapy that they could potentially benefit from. Now, this research team is conducting further research looking at potential molecular differences in breast cancer in Black women, as well as how other social disparities could be playing into an increased risk of breast cancer death in these women. FDA Grants Priority Review to Enhertu for HER2-Positive Solid Cancers The Food and Drug Administration granted a priority review for a supplemental biologics license to Enhertu for the treatment of patients with previously treated metastatic HER2-positive solid tumors that cannot be removed via surgery. Basically what that means is that the drug showed promise in a clinical trial, and now the FDA will work with the pharmaceutical company developing the drug to expedite the review and potential approval of the agent. The agency plans on making its decision on whether or not Enertu will be approved some time in the second quarter of this year. Enertu is an antibody drug conjugate, which is a type of drug that works by finding and binding to certain proteins found on cancer cells — in this case, the HER2 protein. The drug was previously approved for patients with lung cancer and metastatic breast cancer, and now, the phase 2 DESTINY-PanTumo02 trial will help determine if it will be approved for patients with endometrial, cervical, ovarian, bladder, biliary tract, pancreatic or other cancers that are HER2 positive. FDA Grants Fast Track Designation to Avutometinib-Lumakras Combo Also in the regulatory space, the FDA granted a fast track designation to a two drug combination consisting of Lumakras and the novel agent, avutometinib for patients with KRAS G12C-mutant metastatic non-small cell lung cancer. The intended patient population for the regimen is those who have been treated with at least one systemic therapy and have not received a KRAS G12C inhibitor. The regimen is being investigated in the ongoing phase 1/2 RAMP 203 trial, which will analyze the effectiveness of the drug, as well as the overall response rate — which is the percentage of patients whose cancer decreases from the drug — and safety. Findings from the second phase of the trial, which is specifically looking at patients who have not received or did not respond to a KRAS G12-inhibitor are expected to be published some time in the first half of 2024. For more news on cancer updates, research and education, don't forget to subscribe to CURE®'s newsletters here.
It's the most common cancer in women. Chances are – you or someone you know has been personally affected by breast cancer. Research has shown -- the rate of cancer diagnosis rose in adults in their 30s from 2010 to 2019 But there is hope. Promising news on the medical front will hopefully wipeout this disease. We talk about prevention, treatment and the hope on the horizon in this episode.
It's the most common cancer in women. Chances are – you or someone you know has been personally affected by breast cancer. Research has shown -- the rate of cancer diagnosis rose in adults in their 30s from 2010 to 2019 But there is hope. Promising news on the medical front will hopefully wipeout this disease. We talk about prevention, treatment and the hope on the horizon in this episode.
This week's episode is from a recent summit, and we are talking to Dr. Donese Worden, a pioneer researcher taking personalized medicine to the nth degree taking very special care of her cancer patients. She started out in the pain management space, but kept seeing cancer everywhere. The minute they had a diagnosis, they were thrown into chemo, radiation, and surgery, all before they even knew the name of their condition. Donese started digging and found the metabolic theory of cancer and began working with those researchers.You will hear:What is the metabolic theory of cancerHow to work with conventional oncologists to meet the patient's needs and wishesFinding ways to treat patients without also harming themThe best way to personalize treatment (genetics + environment)The benefits of a ketogenic diet and hyperbaric oxygen therapyAnd more!More about Dr. Worden: Dr. Donese Worden is a Naturopathic Medical Doctor, an expert diagnostician, a global health educator whose training in both conventional and alternative medicine affords her the privilege of providing each of her patients with a specific treatment plan that addresses not just the symptoms but the whole person to get to the root of the problem.Connect with Dr. Worden:Website: www.Dr Worden.comFacebook: https://www.facebook.com/DrDoneseWordenNMDInstagram: https://www.instagram.com/DrDoneseWorden/YouTube: https://www.youtube.com/user/DrDoneseWordenTo talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
Today, I have two very special guests with me – Two survivors who are on a mission to build community and create a safe space where people can tell their stories and create a community. Amy Robinson and Maria Bachteal join me to share their journeys with breast cancer, what they are doing differently within the space and why community is crucial with a breast cancer diagnosis. You will hear: Amy and Maria's stories of receiving their diagnoses and looking for a path other than what conventional medicine had to offerThe importance of connecting with others in similar situations Why you need to change the environment you're in once you've received your diagnosisWhy taking a pause and a breath is so important when receiving or finishing a cancer treatmentThoughts on how and why conventional medicine is missing the mark when it comes to breast cancerAnd more!Connect with Amy & Maria:Radiant Healing Together Breast Cancer Learning & Healing Support Community Live events most days and 300+ recorded expert events, classes and meditations Learn more: RHT Free Trial and Free GroupLearn more: RHT-HER2+ Group Free Breast Cancer Meditation Bundle Story Medicine: Doses of Hope, Healing, and Wisdom from Women with Breast Cancer, Edition 1: Lisa's Light- was a no. 1 new breast cancer release on amazon (all proceeds support women with metastatic BC)Healing Nutrition of SonomaRHT website To talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
Content advisory: this podcast contains themes of mental health and suicide. Dr Louise is joined by her patient Trudie Jennings in this episode to talk about the complexities around HRT during and after treatment for breast cancer. Trudie describes how she started HRT to successfully manage crippling anxiety and other menopause symptoms and a few months later she was diagnosed with an aggressive breast cancer. NICE guidance states women should stop taking systemic HRT if they are diagnosed with breast cancer. However, after careful discussion with her cancer doctor and nurse, Trudie decided to continue with HRT during her treatment as, for her, the menopause symptoms were more challenging than her cancer treatment. Trudie and Dr Louise discuss shared decision making and informed consent, and how important it is for women with and after breast cancer to be fully informed about potential risks, benefits and uncertainties about HRT following a breast cancer diagnosis so they can make the best decision that is right for them. Trudie's three tips for women who have had breast cancer and are struggling with their menopause: Know that as a patient you do have choices about whether to start or continue HRT after breast cancer treatment. Speak to your doctors and nurses and be informed so that you can make the right, personalised, decision for yourself. Trudie has found her healthcare professionals in cancer care open and helpful when discussing her need for HRT. You know your own body best, so listen to your body to get the treatment that will be best support you. Contact the Samaritans for 24-hour, confidential support by calling 116 123 or email jo@samaritans.org Click here to find out more about Newson Health
In this compelling episode of "Let's Talk About Your Breasts," Dorothy welcomes Claudia Farinola. Claudia discusses the challenges and enduring effects stemming from her battle with breast cancer and how, despite her own struggles, she has helped the Emma Jacobs Breast Cancer Foundation raise thousands of dollars for The Rose. This heartfelt conversation sheds light on the long-term ramifications breast cancer survivors may face and highlights the profound impact of community support.See omnystudio.com/listener for privacy information.
Following a weekend of speculation, the most senior woman in government Suella Braverman has been sacked from her role as Home Secretary. To discuss Emma is joined by Lucy Fisher, the Whitehall Editor for the Financial Times; and Claire Pearsall, former Home Office special advisor under Amber Rudd and Sajid Javid. The gripping BBC One drama ‘Time' focuses on the stories of three women, and shows the stark differences for female and male prisoners. Emma is joined by Time's screenwriter, Helen Black, who has first-hand experience of the criminal justice system from her past career in the law, and Lady Unchained, who was sentenced to two and a half years in prison for grievous bodily harm following a fight in a club while trying to protect her sister. She is now a poet, performer and broadcaster. The actor Natalie Cassidy pays tribute to the late Anna Scher who taught children in North London to act for more than 50 years. How is our interaction with AI shifting our concepts of intimacy and sexuality as humans? Emma Barnett talks to the Kate Devlin Kate Devlin who's a Reader Artificial Intelligence & Society at King's College London and the author of Turned On: Science, Sex and Robots, and to Trudy Barber, Senior Lecturer at Portsmouth University in Media Studies. Tens of thousands of women in England could benefit from a drug that helps prevent breast cancer. Anastrozole, used for many years to treat the disease, has now been licensed as a preventative option, and almost 300 thousand women will be eligible to take it. But is it as big a step forwards as it seems? Former surgeon and breast cancer survivor Dr Liz O'Riordan joins Emma to discuss. Presenter: Emma Barnett Producer: Emma Pearce
More and more women are living and thriving far beyond breast cancer. The journey is difficult, but there are amazingly committed providers working to help us succeed. One of them just happens to be Dr. Reid's big sister. Join Jennifer Reid, MD as she interviews Jodi Brehm, MD, an award-winning breast surgeon and women's health advocate with Advocate Health Systems in Wisconsin. Dr. Brehm's professional goal has always been to help her patients through their breast cancer journey with empathy, support, and encouragement—there is life after breast cancer. We Discuss:1) Dr. Brehm's recommendation for mammograms: how often, what type?2) Risk factors for breast cancer and how to protect yourself.3) The treatment pathway after breast cancer diagnoses, and why outcomes are so much better in recent years.References from Episode:Susan B. Komen Organization https://www.komen.org/Dr. Jodi Brehm attended the University of North Dakota for her undergraduate and medical school degrees and completed her general surgery residency at Rush University, Medical Center. She is a Fellow of the American College of Surgeons and has been a practicing breast surgeon since 2008. She has also been awarded the Business Journal Women of Influence Award in the category of Innovation and has been elected a Castle Connolly Top Doctor since 2015, nominated by her fellow physicians for excellence in clinical care. When not at the hospital, her favorite things to do are spending time with her husband and three children, riding horse, and adding to her growing menagerie of pets. She thinks her kid sister is very cool. Dr. Brehm: https://care.aurorahealthcare.org/doctors/jodi-l-brehm-mount-pleasant-general-surgeryJennifer Reid, MD: thereflectivedoc.comSeeking a mental health provider? Try Psychology TodayNational Suicide Prevention Lifeline: 1-800-273-8255SAMHSA's National Helpline - 1-800-662-HELP (4357)Dial 988 for Mental Health EmergencyThoughts and opinions expressed on show are those of host and guests, and not associated with any academic institution.Disclaimer:The information and other content provided on this podcast or in any linked materials, are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment. All content, including text, graphics, images and information, contained on or available through this website is for general information purposes only.If you or any other person has a medical concern, you should consult with your health care provider or seek other professional medical treatment. Never disregard professional medical advice or delay in seeking it because of something that have read on this website, blog or in any linked The Reflective DocWebsite - Instagram - Facebook - Linked In - Twitter - Think Like a Shrink Blog on Psychology Today