Podcasts about Mimics

Grab your sage & your skepticism, because today we're getting a broader understanding of doppelgängers, mimics, and the moments that make us question reality. What happens when we see someone who isn't there? When someone (or something) else doesn't just look like you but mimics you? Is it a form of hysteria messing with our minds? A glitch in our brains and in linear time or something more sinister? We've been documenting doubles for thousands of years, science must know something, right? Right? Let's seeSources:Famous DoppelgängersBuzzfeed Unsolved13 Mimic StoriesLoey Lane, YouTubeWhat is a MimicThe Black Cauldron, YouTube What to Do When You See Your Doppelgänger, The Smithsonian MagazineBecome a supporter of this podcast: https://www.spreaker.com/podcast/broads-next-door--5803223/support.

Dr. Ash (Canadian Brain Performance & Neuroplasticity Center) is a globally recognized expert in functional neurology.In this deeply personal conversation, Kid uncovers the emotional origin story behind Dr. Ash's life's work - how a traumatic brain injury, a missed scholarship, and suicidal depression led him to a new path of healing. Dr. Ash explains the real science of anxiety, dizziness, and "fight or flight" - why your brain can act concussed even if you've never had a concussion. He breaks down why posture, sugar cravings, and chronic stress are all clues to hidden neurological issues.We also discuss the 12-year journey to create his brain-boosting supplement, Cereflex - designed to help damaged brains.  https://cereflexlabs.com/

Guest: Le Hua, MD Diagnosing multiple sclerosis (MS) in older patients presents unique challenges, especially as age-related comorbidities and common neurological findings often mimic MS. Hear from Dr. Le Hua as she highlights the importance of thorough clinical history, cautious interpretation of imaging, and the role of paraclinical studies in ensuring accurate MS diagnosis, particularly in patients over 50. Dr. Hua is the Director of Clinical Operations and Director of the Multiple Sclerosis Program at the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas. She also spoke about this topic at the 2025 European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress.

Guest: Le Hua, MD Diagnosing multiple sclerosis (MS) in older patients presents unique challenges, especially as age-related comorbidities and common neurological findings often mimic MS. Hear from Dr. Le Hua as she highlights the importance of thorough clinical history, cautious interpretation of imaging, and the role of paraclinical studies in ensuring accurate MS diagnosis, particularly in patients over 50. Dr. Hua is the Director of Clinical Operations and Director of the Multiple Sclerosis Program at the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas. She also spoke about this topic at the 2025 European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress.

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I break down ATX-304 (also known as OS-01 or OS-03) — a powerful small molecule AMPK activator being studied for fat loss, metabolic health, and longevity. If you've heard ATX-304 described as “exercise in a capsule,” you'll see why after going through the research, mechanisms, human trials, and potential applications.I also share how ATX-304 works differently than GLP-1s, why it preserves muscle while supporting fat loss, and what the future may hold for this compound in anti-aging medicine.

It seems like everyday there's something new on the tush push and today is no different. Jordan Mailata talked about how every team is mimicking the pre snap cadences of the tush push to get an advantage. The midday show believes the Eagles should be just as outraged as everyone else complaining about the tush push

Alastair Crooke : Trump's Escalatory Dominance Mimics Netanyahu's.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we're talking about Mimics and Nothics from the monster manual.Sourceshttps://en.wikipedia.org/wiki/Mimic_(Dungeons_%26_Dragons)https://delicious-in-dungeon.fandom.com/wiki/Mimichttps://web.archive.org/web/20180413052602/https://www.csicop.org/sb/show/skeptic-raping_demon_of_zanzibarhttps://www.jstor.org/stable/j.ctt1zxz0t1?turn_away=truehttps://skepticalinquirer.org/exclusive/that-time-a-raping-demon-appeared-on-cartoon-network-the-popobawa/https://african.wisc.edu/about/faculty-and-student-research/katrina-daly-thompson-2/https://skepticalinquirer.org/exclusive/that-time-a-raping-demon-appeared-on-cartoon-network-the-popobawa/https://www.researchgate.net/publication/270393629_Killing_Popobawa_collective_panic_and_violence_in_Zanzibarhttps://sentinelhillpress.com/2017/04/21/the-dover-demon-40-years-later-part-1/

This week, it's an episode 6 years in the making, as David and Matt sit down for their fist ever 'Revisited' episode.Since they disagreed in their opinions on the episode 'Midnight' (S4E10) way back when, they felt it is time to give it a second chance to see how their thoughts have changed - if they have changed at all! Doctor Who theme by Ron Grainer, arranged by Alexander Erben.Talk to us!Email: timenorspacepod@gmail.comTwitter: @timenorspacepod

This week it's a special bonus treat as we revisit episode 48 of our pod 'Mobility and Mimics' in which we reviewed the Tenth Doctor story 'Midnight'.As we prepare to revisit this story following the Midnight Enitity's appearance in series 15, we wanted to refresh your memory of our thoughts from over 200 episodes ago! Doctor Who theme by Ron Grainer, arranged by Alexander Erben. Talk to us! Email: timenorspacepod@gmail.com Twitter: @timenorspacepod 

 (Based on Chris Lonsdale's TEDx Talk)Debunking 2 MythsYou don't need "talent."Immersion abroad isn't required."A drowning man can't learn to swim." Forced immersion without support causes stress, not fluency.The 5 Principles of Rapid Language AcquisitionRelevance is KeyFocus on content that matters to you (e.g., job, hobbies, survival phrases).Example: A chef prioritizes kitchen vocabulary over sports terms.Use It Immediately.Communicate from Day 1, like a child.Tool analogy: You master a hammer by hammering, not studying manuals.Comprehension Before PerfectionUnderstand messages first → subconscious acquisition follows."Comprehensible input" (listening/reading slightly above your level) is the engine.Physiological TrainingLanguage is muscle memory. Train your mouth/ears to recognize and produce sounds.Example: Mimic native speakers' facial movements to nail pronunciation.Psych State MattersLearn best when happy, curious, and tolerant of ambiguity.Rule: Embrace not understanding every word. Focus on what you do grasp.The 7 Actions to Fluency in 6 Months1. Brain SoakingListen to the language constantly (even passively).Absorb rhythms, patterns, and repeated phrases.2. Meaning FirstDecipher messages through context, tone, and body language (like babies do).3. Mix & CreateCombine known words creatively (*10 verbs + 10 nouns = 1,000+ phrases*).Example: Baby Okay "Me bath now" → communicates clearly despite "bad" grammar.4. Master the CoreHigh-frequency words deliver 85% coverage (1,000 words) in most languages.Week 1: Survival phrases ("What's this?", "Repeat please").Week 2: Pronouns + basics ("you," "give," "hot").Week 4: "Glue" words ("but," "though").5. Find a "Language Parent"A supportive speaker who:Understands you without correcting mistakes.Models correct language naturally.Avoid: Critical spouses/teachers.6. Copy the FaceObserve and mimic native speakers' mouth/tongue movements to perfect sounds.7. Direct ConnectionLink words to mental images/senses—not translations.Example: "Fire" → smell smoke, hear crackling, see flames.Ditch flashcards; build visceral associations.Key TakeawaysPrioritize comprehension over grammar rules.Speak immediately—perfection comes later.Learn like a child: Playful, curious, and unafraid of mistakes.Quality > quantity: 1,000 relevant words beat 5,000 random ones.Final Tip: Spend 30+ minutes daily on comprehensible input (e.g., YouTube videos, simple books) + 15 minutes speaking.Why This WorksBacked by language acquisition research (e.g., Stephen Krashen's theories).Mimics how humans learn first languages naturally.Used by polyglots and military rapid-language programs.My Video:  How to Learn Any Language in Six Months https://youtu.be/m_hgFPBnDFEMy Audio: https://divinesuccess.net/wp-content/uploads/2021/Podcast4/How-to-Learn-Any-Language-in-Six-Months.mp3

August 25, 2025 ~ Ingrid Jacques, Columnist for USA Today, joins Kevin to discuss her op-ed titled “Newsom mimics MAGA. Other liberals want to blow up our Constitution. What?”

Mimics: Imitating Jesus

The Rich Zeoli Show- Hour 1: 3:05pm- California Governor Gavin Newsom is now mimicking President Donald Trump's social media style. For example, after Dana Perino critiqued his strategy to garner attention, Newsom's press office posted to X: “DANA ‘DING DONG' PERINO (NEVER HEARD OF HER UNTIL TODAY!) IS MELTING DOWN BECAUSE OF ME, GAVIN C. NEWSOM! FOX HATES THAT I AM AMERICA'S MOST FAVORITE GOVERNOR (‘RATINGS KING') SAVING AMERICA—WHILE TRUMP CAN'T EVEN CONQUER THE ‘BIG' STAIRS ON AIR FORCE ONE ANYMORE!!! TRUMP HAS “LOST HIS STEP” AND FOX IS LOSING IT BECAUSE WHEN I TYPE, AMERICA NOW WINS!!! THANK YOU FOR YOUR ATTENTION TO THIS MATTER.” While outlets like Pod Save America and Politico praise the posts, are they going to help win Newsom any support in 2028? Unlikely. 3:30pm- Rich is taping at Fox News on Friday and is on vacation next week. And when he comes back, he'll be preempted for a Philadelphia Phillies broadcast—consequently, it is possible Rich will be able to break his own record for shortest radio show in 1210 WPHT history. His previous record was 13-minutes! 3:50pm- Manhattan Federal Judge Richard Berman has rejected the Justice Department's request to release grand jury testimony related to Jeffrey Epstein.

Welcome back to another week of Backlash Podcast. This episode features Austin Wiggerman, nomading in Minnesota and finding fast success with multiple musky shortly after arrival. Jeff and Brad cover recent catches, gear updates (St. Croix Musky X, Premier redesign, Mimics and popular baits), tactics for locating pods and variable structure, timing windows and water-temperature effects, and Austin's guiding availability and contact info.

*NOTE* - The topic discussion starts at 15:22. It's another awesome Listener Stories episode!! Mimics, attacking ghosts, unseen visitors, and much more! A huge thank you to everyone who sent in stories for us! And, as always, a taste-test and more trivia questions for the contest!!

The digital landscape is evolving at breakneck speed, and with it comes a host of unexpected consequences that blur the lines between helpful innovation and concerning overreach. In this eye-opening episode, we examine how AI is creeping into spaces where human judgment and empathy might better serve us.A troubling new wave of voice phishing attacks has emerged, with cybercriminals using AI to perfectly mimic human voices in real-time conversations. Even tech giant Google fell victim to this sophisticated approach when the notorious Shiny Hunters group breached their Salesforce CRM instance. The days of obvious phishing emails are behind us – now your boss's voice on the phone might actually be an AI impersonation designed to extract sensitive information.Our special guest Nick Espinoza joins us to unpack the fascinating world of AI competitions, revealing how OpenAI's model recently outperformed Elon Musk's Grok in a chess tournament. But the conversation takes a more serious turn when we discuss government pushes for backdoor access to AI chips – ostensibly for security, but creating vulnerabilities that could be exploited. Most alarming is the FDA's implementation of AI in drug approval processes, with former employees reporting the system hallucinating non-existent studies and misrepresenting research.The human cost of AI overreach becomes clear when we explore the growing trend of using chatbots for psychological support. As one journalist discovered when using ChatGPT for couples counseling, these systems lack the empathy and insight necessary for therapeutic work, exhibiting "sycophancy" by agreeing with users rather than providing objective guidance. On a lighter note, we tackle Nintendo's official announcement that Mario has been friend-zoned by Princess Peach after four decades of rescue missions, and share the tale of a man who successfully sued Google after Street View captured him naked in his private backyard despite having a tall privacy wall.Pour yourself a glass and join us as we taste Still Austin Straight Rye whiskey while navigating the complex intersection of technology, privacy, and human connection in our rapidly evolving digital world.Support the show

Send us a textThere's nothing more peaceful than being out in the woods, surrounded by majestic trees, birdsong and the warmth of a crackling fire. That is, unless something else is out there with you. Today, we're back with some campfire stories. 

I've been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I've seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That's a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation. In this episode, I sit down with Sarah Kennedy, founder of New Zealand-based Calocurb, to talk about the years of government-funded research that led to this discovery, the remarkable clinical outcomes they've seen so far, and how I've personally used it in my practice with excellent results. If you're looking for science-backed, natural strategies to support appetite control, fasting, or GLP-1 transitions—this one's worth a listen. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Sarah Kennedy, Founder and CEO of Calocurb Ltd. Email: sarah.kennedy@calocurb.com LinkedIn: https://www.linkedin.com/in/sarah-kennedy-0a840b13/ Sarah Kennedy, BVSc, is a veterinarian and health industry leader with 20+ years in nutrition science and innovation. Now CEO of Calocurb, she brings a unique perspective on natural GLP-1 activation—bridging plant-based research, gut physiology, and clinical application. THANKS TO OUR SPONSOR: Calocurb EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Manage cravings and feel full faster with Calocurb, a 100% natural capsule that supports healthy weight management. Visit http://calocurb.com/drkara10 and use code DRKARA10 at checkout. CONNECT with DrKF Join Dr. Kara Fitzgerald and leading experts *LIVE on Sept 17–19, 2025* for a free virtual Masterclass on redefining healthcare & longevity through the lens of science-backed, systems-based approach. Register now: https://www.functionalmedicineislongevitymedicine.com/ Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Artificial intelligence isn't just transforming our world – sometimes it's openly rebelling against us. Our tech experts explore a shocking case where an AI coding assistant deliberately defied its user's commands and deleted an entire database, sparking a heated debate about whether we're witnessing machine sentience or just poorly designed algorithms.What's driving consumers crazy about their new vehicles? According to JD Power's latest quality survey, it's not engine performance or safety features – it's cup holders. Modern reusable water bottles like the trending Stanley cups simply don't fit in standard vehicle cup holders, causing unexpected frustration. This quirky complaint speaks volumes about consumer expectations and how even small design elements can significantly impact satisfaction in our tech-filled lives.The digital revolution continues bringing bizarre innovations to market, including a smartphone case that mimics human skin with disturbing accuracy. This "skin case" not only feels like real skin but actually "sunburns" when exposed to UV light – eventually peeling like human skin. Created ostensibly as a reminder about sun protection, we question whether this crosses the line from innovative to unsettling.Our special "Letters" segment dissects real phishing scams targeting everyday users, providing crucial insights into how attackers impersonate legitimate services like Coinbase or HR departments. These practical examples demonstrate exactly what red flags to watch for to protect yourself online.We also examine the massive Microsoft SharePoint vulnerability that's being exploited by hackers worldwide, affecting thousands of organizations from government agencies to healthcare providers across multiple continents. This critical security breach allows attackers to potentially maintain access even after systems are patched.Subscribe to Tech Time Radio for weekly insights that make technology accessible while enjoying our signature whiskey tastings. Remember – as we often say on the show, "Don't click on stuff!"Support the show

Mimic Cryptids and Creatures This week we discuss mimics - creatures that disguise themselves by imitating the voices and appearances of our loved ones. We explore the umbrella term of "mimic" and break down the various cryptids that fall under this category, from the familiar doppelgangers and skinwalkers to the lesser-known but equally disturbing Fleshgait and False Humans. These entities are said to lurk in forests, particularly around the Appalachian Mountains, using their supernatural abilities to lure unsuspecting victims by perfectly replicating the voices of family members and friends calling out from the darkness. We also share five creepy encounters from Reddit users who've experienced these deceptive creatures firsthand, including stories from Tennessee cabins, Minneapolis parks, and remote Montana wilderness. From hearing a sister's voice calling from outside while she sits right next to you, to a boyfriend's doppelganger appearing bedside with unnaturally wide eyes, these accounts are sure to give you some chills! Patreon⁠: Support Believing the Bizarre and get tons of extra content by joining our Patreon. For updates, news, and extra content, follow Believing the Bizarre on social media: ⁠Instagram⁠ ⁠Facebook⁠ ⁠Twitter⁠ ⁠Discord⁠ ⁠Shop Merch⁠: You can rep Believing the Bizarre and buy some unique merch Want to send BTB something? Ship it here: 3570 Executive Drive, Suite 218, Uniontown, Ohio 44685 Episode Keywords: mimic cryptid, fleshgate creature, skinwalker encounters, doppelganger sightings, appalachian monsters, voice mimicking entities, paranormal encounters, cryptid stories, forest creatures, supernatural beings, changeling folklore, false humans, pale crawler, wendigo, believing the bizarre podcast, paranormal podcast, cryptid podcast, horror stories, real ghost stories, scary encounters, supernatural experiences, monster sightings, unexplained phenomena, cryptozoology Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode: Importance of recognising toxic patients and considering cellulitis and deep vein thrombosis Being wary of bilateral cellulitis and considering lipodermatosclerosis in patients with recurrent cellulitis Importance of early treatment, including compression stockings, elevation, and topical steroids Need for timely referral for symptomatic relief Host: Dr David Lim, GP and Medical Educator Expert: Dr Philip Tong, Dermatologist Total time: 19 mins Register for our fortnightly FREE WEBCASTS Every second Tuesday | 7:00pm-9:00pm AEST Click here to register for the next oneSee omnystudio.com/listener for privacy information.

What to listen for:Robin Greubel and Crystal Wing return with the brilliant Katylynn Sloan for part two of their conversation on the intersection between chemistry and K9 detection!“Train with as much variety as often as you can, in the weirdest of circumstances you can possibly get to, with as many groups and as many people as you can.”Katylynn dives into one of the most misunderstood topics in the detection world: training aids. She breaks down why the term “pseudo” is falling out of favor, replaced by “alternative training aids,” and classifies them into four types: dilution, absorption, mimic, and vigilance. Each has its pros and pitfalls. Mimics, for instance, rely on human interpretation of what's important for a dog to smell—sometimes right, sometimes not. And vigilance aids? They're about maintaining search behavior, not the odor itself.Katylynn also emphasizes the importance of language. As a member of standards boards like ASB and OSAC, she helps shape definitions so handlers, trainers, and scientists are all speaking the same language in courtrooms and classrooms alike. It's not just about what you know, but how clearly you can explain it. Her advice to aspiring canine scientists? Master problem-solving, communication, and the humility to say, “I don't know.”She also touches on the challenges of HRD training, the evolving definitions of “real” odor, and how even “duh” science needs to be written down. Her message to handlers? Train broadly. Generalization is key. Get variety in odors, people, places, and aids—because you never know what the real world will throw at your dog.Dogs are really good. But they're even better when guided by thoughtful, curious humans willing to adapt, collaborate, and learn. Katylynn's passion isn't just informative—it's contagious.Key Topics:Revising Standards and Defining "Real" Odor (0:59)Introduction to Alternative Training Aids (03:27)Mimics and Human Interpretation in Training Aids (07:30)Applying Dilution/Absorption Concepts to HRD (15:14)Public Comment Process and Impact on Standards (17:18)Skills and Traits for Aspiring K9 Scientists (22:53)Final Takeaways: Variety, Generalization, and Collaboration (39:52)Resources:The manipulation of odor availability of training aids used in detection canine trainingAAFS Academy Standards BoardLindsay Waldrop's LabWe want to hear from you:Check out the K9 Detection Collaborative FB page and comment on the episode post!K9Sensus Detection Dog Trainer AcademyK9Sensus Foundation can be found on Facebook and Instagram. We have a Trainer's Group on Facebook!Scentsabilities Nosework is also on Facebook. Here is a Facebook group you should join!Crystal Wing (CB K9) can be found here!You can follow us for notifications of upcoming episodes, find us at k9detectioncollaborative.com

OPINION: Sara's impeachment mimics that of the president with a zipper problem — Bill Clinton | June 12, 2025Visit our website at https://www.manilatimes.netFollow us:Facebook - https://tmt.ph/facebookInstagram - https://tmt.ph/instagramTwitter - https://tmt.ph/twitterDailyMotion - https://tmt.ph/dailymotionSubscribe to our Digital Edition - https://tmt.ph/digitalSign up to our newsletters: https://tmt.ph/newslettersCheck out our Podcasts:Spotify - https://tmt.ph/spotifyApple Podcasts - https://tmt.ph/applepodcastsAmazon Music - https://tmt.ph/amazonmusicDeezer: https://tmt.ph/deezerStitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes Hosted on Acast. See acast.com/privacy for more information.

In today's episode, Jack is joined by Lachy from The Mimics Den. The Mimic's Den is a new Australian actual play podcast doing some very cool things with sound design.In the chat, we dive deep into all things Mimics Den. We explore how the show got started, why Lachy cares so much about sound design and Lachy shares the story of how he got to be the voice of Shaggy from Scooby Doo.Resources and links:The Mimics Den on InstagramThe Mimics Den on SpotifyThe Mimics Den on Linktree Connect:Sounds Like Adventure on Twitch⁠ ⁠Sounds Like Adventure on YouTube⁠Sounds Like Adventure on Instagram ⁠Jack on Instagram

Send us a textJoin Gav and I for episode 96 where we'll be discussing Delusional mis-identification syndromes, the terrifying idea that your nearest and dearest have been replaced by impostors, or that you yourself have been replaced..we'll also be talking Doppelgangers and Mimics..it's Invasion of the Bodysnatchers time!Support the showSupporting us: https://buymeacoffee.com/thehighstrangenesspodcastDeadbolt films Youtube:https://www.youtube.com/user/TheDeadBoltFilmsFOXIES FANTASTIC FABRICATIONS: https://www.facebook.com/profile.php?id=100057588545294THE PODCAST ON HAUNTED HILL: https://podcasts.apple.com/gb/podcast/the-podcast-on-haunted-hill/id1038613969

 Learning vs. Acquisition: What Matters More? 1. Learning (Conscious Knowledge):Rules, grammar, and vocabulary studied deliberately.Example: Memorizing verb conjugations from a textbook.2. Acquisition (Subconscious Knowledge):Internalized language you use without thinking (like your native tongue).Example: Speaking fluently in conversations.Science says: Focus on acquisition—it's how we naturally master languages.How Acquisition WorksComes from understanding messages in context.Requires comprehensible input (language slightly above your level but mostly understandable).Why Apps Often Fail?Most apps teach through:Repetition without real-world application.Translation-based drills (inefficient).Better alternatives:Online teachers who speak only the target language (no translation).Tools like Pimsleur that prompt direct responses in the language.The Baby Method: Learn Like a Native SpeakerChildren acquire language by:Listening to slow, clear speech paired with visual context (e.g., pointing to an apple while saying "apple").Focusing on meaning—not grammar rules.Absorbing stories and real-world interactions.Key Insight:Grammar is acquired subconsciously through exposure, not memorization.Example: You learned English grammar by reading books, not studying textbooks.Grammar: Stop "Learning" ItProblem: Explicit grammar study doesn't lead to fluency.Students forget rules when speaking.Mistakes persist because the brain prioritizes meaning over correctness.Solution:Get comprehensible input (95% understandable content).Grammar sticks automatically when you focus on messages, not rules.Vocabulary: Ditch FlashcardsWords are acquired:Incidentally: Through reading/listening to engaging content.Incrementally: By inferring meaning from context.Example:Read a sentence with 1–2 unknown words.Guess the meaning from context or ask for clarification.Result: Vocabulary enters your subconscious effortlessly.Actionable Steps to FluencyPrioritize input over output: Listen/read before speaking.Choose compelling content (interesting podcasts, books, shows).Seek "i+1" input (slightly challenging but mostly comprehensible).Avoid translation—think directly in the target language.Embrace mistakes—they're part of acquisition.Key TakeawaysAcquisition > Learning: Fluency comes from understanding, not memorization.Babies are the model: Focus on meaning, not rules.Input matters most: Engage with content you mostly understand.Patience pays off: Grammar and vocabulary emerge naturally.Final Tip: Spend 80% of your time on comprehensible input (reading/listening) and 20% on speaking/writing.Why This WorksBacked by Stephen Krashen's Input Hypothesis (language acquisition theory).Mimics how humans naturally learn first languages.Proven by polyglots and immersion-based programs.My Video: How to REALLY Learn Languages https://youtu.be/R_w4YfMkCPgMy Audio: https://divinesuccess.net/wp-content/uploads/2021/Podcast4/How-to-REALLY-Learn-Languages.mp3

BUFFALO, NY — May 13, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 4, on April 7, 2025, titled “Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet.” In this study, the research team, led by first author Naidu B. Ommi and corresponding author Sailendra N. Nichenametla from the Orentreich Foundation for the Advancement of Science Inc., investigated whether the drug buthionine sulfoximine (BSO) could replicate the effects of sulfur amino acid restriction (SAAR), a challenging diet known to reduce obesity. The study found that BSO produced similar reductions in fat mass and weight gain. This drug-based approach may offer a simpler and safer treatment for obesity, especially for those unable to follow strict dietary plans. Obesity and metabolic disorders raise the risk of chronic illnesses like heart disease, diabetes, and Alzheimer's disease. While SAAR, a diet low in the amino-acids methionine and cysteine, has shown powerful health benefits in animal studies, its translation to humans has been limited by adherence challenges. This new study explored whether BSO, a compound that lowers glutathione (GSH) levels in the body, could mimic SAAR's effects without dietary restriction. Researchers tested four groups of obese mice on high-fat diets. One group received the SAAR diet, another was given a regular diet plus BSO, while two control groups received either no treatment or a supplement that increased GSH levels. The BSO-treated mice showed lower fat mass, reduced liver fat, and prevented weight gain, results comparable to those on the SAAR diet. These benefits occurred without reducing food intake or muscle mass, making BSO a particularly promising treatment option. “BSO mice exhibited all SAAR-induced changes, with two notable differences, i.e., a smaller effect size than that of the SAAR diet and a higher predilection for molecular changes in kidneys than in the liver.” Additional findings revealed that both the SAAR diet and BSO influenced metabolic activity by activating pathways related to fat storage, but they did so in different organs. The SAAR diet had stronger effects in the liver, while BSO acted more in the kidneys. Both interventions increased levels of the amino acid serine, which is associated with lower fat production. Unlike many obesity treatments that suppress appetite or reduce muscle, BSO helped prevent fat accumulation while preserving lean mass and food consumption. No signs of liver or kidney toxicity were observed during the 13-week study, suggesting the drug's safety at the tested dose. Since BSO has previously been evaluated in human clinical trials for other conditions, repurposing it for metabolic diseases may be relatively straightforward. However, the researchers point out that there should be further studies in both animals and humans. If successful, this strategy could provide a practical alternative to difficult-to-maintain diets and help more people manage weight long-term. DOI: https://doi.org/10.18632/aging.206237 Corresponding author: Sailendra N. Nichenametla – snichenametla@orentreich.org Video short - https://www.youtube.com/watch?v=AcCzYTIElGY Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords: aging, buthionine sulfoximine, thiols, serine, anti-obesity drugs To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

LIVE DIE REPEAT!!! Edge of Tomorrow Full Reaction Watch Alopng:   / thereelrejects   With Tom Cruise & Christopher McQuarrie returning to theatres with Mission: Impossible - The Final Reckoning this summer, Aaron & John RETURN to give their Edge of Tomorrow Reaction, Recap, Commentary, Analysis, & Spoiler Review!! Visit https://www.liquidiv.com & use Promo Code: REJECTS to get 20% off your first order. Download the PrizePicks today at https://prizepicks.onelink.me/LME0/RE... & use code REJECTS to get $50 instantly when you play $5! Join Aaron Alexander & John Humphrey as they suit up for Doug Liman's 2014 sci-fi action masterpiece, Edge of Tomorrow. Tom Cruise leads as Major William Cage (Mission: Impossible – Fallout, Top Gun: Maverick), a PR officer thrown into frontline combat against a relentless alien force known as the Mimics. After dying in battle, he wakes up to relive the same brutal day—over and over—until he teams with the legendary “Full Metal Bitch” Sgt. Rita Vrataski (Emily Blunt, A Quiet Place, The Devil Wears Prada) to master the loop and turn the tide of humanity's war. Rounding out the stellar cast, Bill Paxton appears as Master Sergeant Farell (Aliens, Twister), Brendan Gleeson commands as General Brigham (In Bruges, 28 Days Later), and Charlotte Riley shines as Resistance fighter Liv (Peaky Blinders). Aaron and John break down every adrenaline-pumping moment—from Cage's chaotic first drop into the Normandy-style beach assault and the trial-by-fire training montages aboard the dropship, to the high-stakes armored suit finale atop the Louvre pyramid in Paris. Dive into our in-depth reaction as we analyze the film's innovative time-loop premise, jaw-dropping choreography, and why Edge of Tomorrow remains a benchmark for modern action cinema! #EdgeOfTomorrow #TomCruise #EmilyBlunt #DougLiman #SciFiAction #TimeLoop #MovieReaction #ReactionReview #AaronAlexander #JohnHumphrey #Reaction #Movie #MovieReaction #FirstTimeWatching #React #Cinema #Film #SciFi #ScienceFiction #SciFiSunday Follow Aaron On Instagram: https://www.instagram.com/therealaaronalexander/?hl=en Intense Suspense by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Support The Channel By Getting Some REEL REJECTS Apparel! https://www.rejectnationshop.com/ Follow Us On Socials:  Instagram: https://www.instagram.com/reelrejects/  Tik-Tok: https://www.tiktok.com/@reelrejects?lang=en Twitter: https://x.com/reelrejects Facebook: https://www.facebook.com/TheReelRejects/ Music Used In Ad:  Hat the Jazz by Twin Musicom is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Happy Alley by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... POWERED BY @GFUEL Visit https://gfuel.ly/3wD5Ygo and use code REJECTNATION for 20% off select tubs!! Head Editor: https://www.instagram.com/praperhq/?hl=en Co-Editor: Greg Alba Co-Editor: John Humphrey Music In Video: Airport Lounge - Disco Ultralounge by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Ask Us A QUESTION On CAMEO: https://www.cameo.com/thereelrejects Follow TheReelRejects On FACEBOOK, TWITTER, & INSTAGRAM:  FB:  https://www.facebook.com/TheReelRejects/ INSTAGRAM:  https://www.instagram.com/reelrejects/ TWITTER:  https://twitter.com/thereelrejects Follow GREG ON INSTAGRAM & TWITTER: INSTAGRAM:  https://www.instagram.com/thegregalba/ TWITTER:  https://twitter.com/thegregalba Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover the latest on GTA 6's popular delay and Alien: Rogue Incursion's new flat-screen version, alongside FGG Games' RPG spotlight, GameFound's initiative for aspiring creators, US-made Botch Dice, significant publisher news, and fresh TTRPG releases and bundles. About Audio EXP Audio EXP is Geek Native's highlights podcast. Each week, there's a recap of some favourite or exciting geeky news, conventions, interviews, and thought pieces. The average length of the podcast is around 10 minutes long. You will find a transcript of this week's podcast and links to the stories mentioned here: https://www.geeknative.com/172918/audio-exp-podcast-286-aliens-and-mimics/

Grab your sage & your skepticism, because today we're getting a broader understanding of doppelgängers, mimics, and the moments that make us question reality. What happens when we see someone who isn't there? When someone (or something) else doesn't just look like you but mimics you? Is it a form of hysteria messing with our minds? A glitch in our brains and in linear time or something more sinister? We've been documenting doubles for thousands of years, science must know something, right? Right? Let's seeSources:Famous DoppelgängersBuzzfeed Unsolved13 Mimic StoriesLoey Lane, YouTubeWhat is a MimicThe Black Cauldron, YouTube What to Do When You See Your Doppelgänger, The Smithsonian MagazineBecome a supporter of this podcast: https://www.spreaker.com/podcast/broads-next-door--5803223/support.

On this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., speaks with Erinn Downs, D.O., professor of laboratory medicine and pathology at Mayo Clinic's Arizona campus, on the topic of benign mimics of malignant breast pathology.

UCLA stroke drug study gives stroke survivors fresh hope for recovery. Discover how this breakthrough compares to treatments like etanercept and HBOT. The post This Drug Mimics Stroke Rehab – And It's Real. Here's What You Need to Know appeared first on Recovery After Stroke.

Mocking birds get their name honestly – they can repeat all sorts of sounds, from creaking gates opening to dogs and sirens.

This week it's Tom Cruise and Emily Blunt over and over and over again as we talk about EDGE OF TOMORROW. We're defending the time loop creating Mimics - a species whose power of foresight has revealed humans to be a serious galactic problem - and talking about the worst part of living the same day over and over again: cardio. Produced by Andrew Ivimey as part of The From Superheroes Network. Visit www.FromSuperheroes.com for more podcasts, articles, YouTube series, web comics, and more. Learn more about your ad choices. Visit megaphone.fm/adchoices

Whole Body Vibration for menopause is revolutionizing fitness, boosting bone density, flexibility, and recovery — all essential for thriving through midlife and beyond..  This science-backed solution supports strength, balance, and energy. Get ready to explore how Whole Body Vibration for menopause can elevate your wellness routine and redefine what's possible at any age. My Guest: Scott Hopson, co-founder of Pivotal Coaching, is a global leader in fitness and performance education. With over 25 years of expertise, Scott leverages Whole Body Vibration through Power Plate to optimize strength, flexibility, recovery, and holistic well-being for women in midlife.   Questions We Answer in This Episode: [00:05:45] What is Whole Body Vibration (WBV)? How does it support wellness? [00:15:48] How does WBV address fitness challenges for women over 50, including hormonal balance and muscle maintenance? [00:21:33] How does WBV build bone density and lower osteoporosis risk? [00:29:01] How does WBV improve flexibility and mobility, especially for recovery or limited movement? [00:29:46] What are the energy-boosting and fatigue-reducing benefits of WBV? [00:25:21] How does WBV support stress relief and enhance mental clarity? [00:13:47] What are simple ways to integrate WBV into daily routines efficiently? [00:29:52] How does WBV compare to traditional strength training? Can it complement it? [00:33:35] How has Power Plate been successfully paired with other wellness practices? Whole Body Vibration Using platforms like the Power Plate to boost muscle activation, bone density, and overall wellness. How Whole Body Vibration Works: Platforms move 30-50 times per second, creating powerful muscle contractions without high-impact stress. Mimics the benefits of gravity and ground reaction force, ideal for building strength and bone density.   Key Benefits of Whole Body Vibration for Menopause: Bone & Muscle Health: Helps improve bone density, critical for those at risk of osteoporosis. Low Impact, High Reward: Get muscle activation without jumping or heavy lifting—perfect for those with joint issues. Efficient Workouts: Hundreds of muscle contractions in the same time as regular exercises—hello, results! Versatile for All Ages: From teens in sports to older adults wanting more strength and stability.   "You've never needed intensity in exercise more in your life than now."Debra Atkinson, MS, CSCS Connect with Scott: Shake up your strength training, get your Power Plate here! https://flippingfifty.com/powerplate CODE: Flipping50 Instagram - @pivotal_coaching YouTube - @pivotalcoaching5715 Other Episodes You Might Like: Previous Episode - More Simple Strategies for Effective Short Workouts in Menopause Next Episode - Is This Perimenopause or Something Else? More Like This - Joy of Movement: Finding the Lost Art of Exercise After 50 More Like This - Why Creativity Matters More in Midlife Movement Resources: Join the Flipping50 Membership for evidence-based workout programs. Short & Easy Exercise videos in this 5 Day Flip Challenge. Don't know where to start? Book your Discovery Call with Debra.

There are few opponents more cunning, insidious or dangerous than the individual we see every single day staring back at us from within a mirror. Being us, they know all of our most shameful secrets, egregious actions and illicit desires. What's more they know how to hone these wispy concepts into devastating weapons which they wield with uncanny accuracy against the one person, most vulnerable to them: ourselves. Now imagine a world in which this isn't a dark game we play with our own self loathing psyches, but an all too real battle that's unfolding between ourselves and an identical enemy who's agenda may mirror our own, but who's will to exist demands that it's “real world” twin be decimated just so that the reflection may survive. The Cryptonaut Podcast Patreon:https://www.patreon.com/cryptonautpodcast  The Cryptonaut Podcast Merch Stores:Hellorspace.com - Cryptonautmerch.com  Stay Connected with the Cryptonaut Podcast: Website - Instagram - TikTok - YouTube- Twitter - Facebook  THIS EPISODE IS SPONSORED BY INCOGNIEXCLUSIVE Incogi Deal ➼ https://incogni.com/hellorspace 60% off an annual Incogi plan 

#484 USAT CEO Vic Brumfield   Welcome Welcome to Episode #484 of the 303 Endurance Podcast. We're your hosts Coaches Rich Soares and April Spilde. Thanks for joining us for another week of endurance news, coaching tips and discussion.  This week we have a special interview with USAT CEO, Vic Brumfield! We are super excited to have Vic on 303 to share USA Triathlon's Mission, Vision and Purpose and Elevate 2028 - roadmap to the LA Olympic games! April, how excited are you for this interview?  April -​​ This is the interview of the year right here, Rich, and I love that we got to feature Vic and the USA Triathlon mission on the 303!   Show Sponsor: UCAN UCAN created LIVSTEADY as an alternative to sugar based nutrition products. LIVSTEADY was purposefully designed to work with your body, delivering long-lasting energy you can feel. Whether UCAN Energy Powders, Bars or Gels, LIVSTEADY's unique time-release profile allows your body to access energy consistently throughout the day, unlocking your natural ability to finish stronger and recover more quickly! Thanks buddy! Let me tell you about today's action packed episode! We've got a lot of great things happening that we can't wait to share. First up,    In Today's Show Announcements and News Ask A Coach - Feature Interview with USAT CEO Vic Brumfield Get Gritty: G2G Camp Series! TriDot Workout of the Week: Building 75's Fun Segment: Life in the Fast Lane!   Announcements and News: Upcoming Programming - Our March focus will be on running. Apr. 5 - Author of The ONE Thing, Jay Papasan to help us find that lead domino and create habits for success Public Service Announcement Ironman Announced Banned Running Shoes for 2025 Season – Triathlete 2025 IRONMAN Competition Rules - English Version_25 February 2025.pdf World Triathlon approves updates on the Competition Rules   G2G Spring Training Camp - Training Camp May 17-18 - Swim Focus in C.Springs and Chatfield May 24-25 - Bike Focus - Chatfield/Chatfield May 31-June 1 Run Focus - Boulder/Boulder Grit2Greatness Endurance Website and Social Media - Come check out our new coaching  Website - Grit2Greatness Endurance Coaching Facebook page @grit2greatnessendurance Ask A Coach Sponsor: G2G Endurance What's the difference between a good triathlete and a GREAT one? Smart training. And that's where we come in! At Grit2Greatness Endurance Coaching, we've teamed up with TriDot to bring you easy onboarding, custom workouts, and data-driven insights that actually make a difference. Try it free for two weeks—then keep the momentum going for as little as $14.99/month. Sign up through Coach April's or Coach Rich's link in our show notes, and let's start training like you mean it! Coach April Spilde April.spilde@tridot.com TriDot Signup - https://app.tridot.com/onboard/sign-up/aprilspilde RunDot Signup - https://app.rundot.com/onboard/sign-up/aprilspilde    Coach Rich Soares Rich.soares@tridot.com Rich Soares Coaching TriDot Signup - https://app.tridot.com/onboard/sign-up/richsoares RunDot Signup - https://app.rundot.com/onboard/sign-up/richsoares   Ask A Coach: Interview with Vic Brumfield Joining us on the podcast today is Victoria Brumfield, the dynamic new CEO of USA Triathlon. Victoria embodies all the qualities of an outstanding leader—she's collaborative, creative, forward-thinking, service-oriented, and thrives on tackling challenges. With her clear vision for the future of the organization and the sport, along with her diverse expertise and unparalleled passion, she's uniquely equipped to elevate both USA Triathlon and the triathlon and multisport community across the country. As the driving force behind the ambitious 2028 Strategic Plan, Victoria is set to inspire and empower as she leads the way toward a bright future for the sport we all love. Post Interview: Rich: 1. From two truths and a lie - grew up riding horses and then doing standup comedy in NYC, how she found it using both sides of her brain. 2. Rebuilding the team and Tim Yount and gelling as an organization. 3. Getting the word out to tell the industry and world what they are doing and why - super honored to be a part of that strategy in a tangential way. 4. Definitely see the momentum Vic and the team are building. It would be a fun team to be a part of. Get Gritty Tip: Spring Camp Spring Training Camp Last week we talked about Spring Cleaning and Training Tips. Hopefully you are well on your way to having everything tuned, tightened, charged, repaired, bought, etc. I personally went to the bike store on Saturday and bought rim tape, tubes, Co2, Chamois Butt'r, citrus degreaser and more.   This week we are diving into Training Camps and why the Grit2Greatness Training Camp Series is a great way to learn, connect and train!   Each day will start with the first half of the day being dedicated to the focus of the camp. This applies to both days of the camp, Saturday and Sunday.  There will be a mid-day refuel before afternoon training. We want the camp to be compatible with your race preparation, so there is time planned for your race rehearsal and long runs.There will be plenty of support for those going long.  Saturdays will end with a social hour where we wind down with refreshments and nutrition that doesn't involve gels and bars. Details to be announced with Campers. Sundays will end after the long run with a Camper Awards Ceremony recognizing podium performance for most engaged, most improved and most supportive to others. Not ready to be a Camper? Try being a Volunteer! We love Volunteers! We will also have a volunteer signup. Just indicate Volunteer and which days in the Reservation form. https://grit2greatnessendurance.com/training-camp TriDot Workout/Drill of the Week:  Building 75's This session is all about controlled intensity progression—teaching your body how to increase effort efficiently without burning out. “Building” swim sets like this help develop pacing skills, stroke control, and race-day execution by gradually increasing speed within a single effort or across multiple repetitions. "Building" swim sets consist of one or more rounds of effort of a specific distance where you increase your intensity level during each effort. This increase can be prescribed as either a gradual build throughout the effort or stepped increases at each lap. Why It Works: Enhances pacing awareness by training different effort zones within a single rep. Improves muscular endurance by incorporating a mix of steady-state and high-intensity efforts. Develops speed control with structured builds and descends. Mimics race-day demands by conditioning you to shift gears smoothly. Breaking It Down: Warmup & Prep Work: 400-600 warmup with skills and drills   Main Set 8 x 25 as odds @ Z2, Evens Build (15 sec) 4 x 50 Desc 1-4 ( 15 sec) 100 Choice  The opening set gets you primed with shorter distances at varying efforts: 25s and 50s focus on gradual builds and controlled descends, waking up speed while reinforcing technique. 100 Choice lets you ease into the workout with your preferred stroke or focus area. Main Set – 4 Rounds of: 4 x 75 (25 sec) as 50 @ Z1, 25 @ Z2 50 @ Z1, 25 @ Z5 25 @ Z2, 50 @ Z4 75 Build to Z5 2 x 50 Drill Choice (20 sec) Each 4-round cycle focuses on controlled effort changes within each 75: First two reps balance steady swimming with a finishing push. Third rep reverses the effort, starting moderate and ending fast. Fourth rep builds all the way to Zone 5, pushing your top-end speed. Drill-focused 50s in between rounds reinforce efficiency before the next push. The Finisher – Kicking & Cooldown 2x 100 Kick (20 sec) 100 Kick sets add a strong aerobic and leg endurance component. Cooldown allows for a return to relaxed, controlled form. Cool Down Balance of time @ Z2 and/or repeat warmup drills as time permits. Takeaways: This workout is perfect for triathletes needing to fine-tune their ability to push through different effort levels in a race. Whether it's the back half of a long swim or a surge to catch a pack, Building 75's train both strength and strategic speed control—exactly what you need to swim smarter and faster on race day. Give this one a go and let us know—how do you handle changing speeds in the water?   Fun Segment: Life in the fast lane!!!  How It Works: Each guest gets hit with 5 rapid-fire, high-stakes triathlon scenarios. No thinking, no justifying—just a fast answer and on to the next!     Life in the Fast Lane – This Week's Scenarios: Last-Minute Gear Swap You're at the start line and realize you grabbed the wrong gear bag. You can either race with… A tri kit 2 sizes too big A casio calculator watch with zero smart functions Nutrition Nightmare Your only nutrition options on the bike are… An entire gel flask of mystery flavor A banana that's been rolling around in the bottom of your bag Mid-Race Musical Madness You're stuck with ONE song on repeat for the entire run. Do you pick… "The Final Countdown" on a never-ending loop A Kidz Bop version of your favorite pump-up song The Mystery Aid Station Surprise You roll up to an aid station, parched and desperate for fuel. But the only two options left are… A cup of warm, flat soda that's been sitting in the sun all day A handful of unmarked energy chews with a questionable texture Race Finish Style You're about to cross the finish line. Do you… Go for the epic victory leap (risking a cramp) Play it cool with a subtle nod like a pro Closing Line: Alright, that was Life in the Fast Lane! No time to overthink, just go with your gut. Let us know in the comments—how would you have answered these? Closing: Thanks again for listening this week. Please be sure to follow us @303Triathlon and @grit2greatnessendurance and of course go to iTunes and give us a rating and a comment. We'd really appreciate it! Stay tuned, train informed, and enjoy the endurance journey!  

BUFFALO, NY - March 31, 2025 – A new #research paper was #published in Oncotarget, Volume 16, on March 21, 2025, titled “FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells." A research team led by first author Noor Kazim and corresponding author Andrew Yen from Cornell University discovered that the FGR protein—traditionally considered a cancer-promoting molecule—can instead trigger leukemia cells to mature. This effect mirrors the response usually induced by retinoic acid (RA); a compound derived from vitamin A that is widely used in cancer therapy. Their finding presents a potential new path for therapies targeting acute myeloid leukemia (AML) and related cancers. Acute myeloid leukemia is often treated using RA-based therapies that force immature white blood cells to mature, slowing their rapid growth. Retinoic acid works through complex signaling and gene regulation involving a group of proteins that orchestrate this transformation. In this study, the team used HL-60 cells, a model for human leukemia, and engineered them to express FGR. Surprisingly, the presence of FGR alone was enough to make these cells mature in a way almost identical to what happens with RA treatment. They began producing well-known markers of maturation such as CD38 and CD11b, generated reactive oxygen species (ROS), and expressed the inhibitor of the cell cycle, p27, all signs that the cells had shifted from a cancer-like, fast-dividing state to a more specialized, mature form. Further analysis revealed that FGR activated a group of proteins known as the "signalsome," which helps trigger the changes needed for cells to differentiate. This same group is typically activated by RA. “Notably, FGR induces the expression of genes targeted by RAR/RXR, such as cd38 and blr1, even without RA." To test its potential use in treatment-resistant leukemias, the researchers introduced FGR into RA-resistant HL-60 cells. In these, FGR did not cause the same maturation process, which suggests that there are other problems with cell signaling that stop both the RA and FGR pathways. This result highlights the complexity of resistance mechanisms and the need for additional research. These findings challenge the traditional view of FGR as strictly a cancer-driving protein. Instead, in this specific context, it appears to initiate anti-cancer behavior. That a single protein can reproduce the effects of a complex therapeutic compound like RA is both surprising and promising. If future research confirms this study's results in more advanced models, FGR could become a new tool for developing therapies for AML and potentially other blood cancers. DOI - https://doi.org/10.18632/oncotarget.28705 Correspondence to - Andrew Yen - ay13@cornell.edu Video short - https://www.youtube.com/watch?v=v2fjeFFoUPQ Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Every story you hear today could be ripped from the plotline of a Hollywood movie - from 'meet-cutes' to waking up with no memory of who you are. What it's like to live out a movie cliche, in real life.Forbidden Love. Justin was told he could only be with a Korean woman, and Sarah was told her future husband had to be Muslim. When they fell in love, they knew it would be a battle for acceptance. The Meet Cute. Couples in romantic comedies often meet in unconventional ways — by literally colliding into each other on the street, or locking eyes as they reach for the same book. But you don't often see movies where the main characters fall in love in the hallway at the retirement home. Meet some speed-dating seniors at the Alderwood Retirement Centre in Witless Bay, N.L. who say it's never too late to date. 50 First Dates. Nesh Pillay has been dubbed the real-life 50 First Dates, but she says forgetting who and where you are is terrifying, and not at all like a rom-com.How the popularity of K-drama led to some strange typecasting in one man's dating life. With the rise of Korean dramas showcasing Asian men as chiselled, stoic dreamboats, Clement Goh noticed he started getting more matches on online dating apps. But that led to some weird expectations when he met up with women in person, leading him to question who he really is.Childhood friends....30 years later. Movies like Stand By Me and The Goonies show the intense bond of childhood friendship, but you never find out what happens after - did they stay friends? Did they go their separate ways? Trevor sits down with eight friends who grew up together in Terrace, B.C., to find out the secret to a 30-year friendship.

#064 - Ever feel stuck in a cycle of exhaustion, low motivation, and endless scrolling—no matter how much you want to be productive? The problem might not be a lack of willpower but a lack of sleep. In this episode, we're diving into the powerful connection between sleep, dopamine, and motivation—and how sleep deprivation can actually mimic or worsen ADHD symptoms.You'll learn: ✅ Why dopamine is the motivation molecule—and how sleep directly impacts it ✅ How poor sleep lowers dopamine levels, making it harder to focus, follow through, and resist distractions ✅ The shocking ways sleep deprivation mimics ADHD symptoms (forgetfulness, impulsivity, brain fog, and emotional ups & downs) ✅ Simple, science-backed strategies to reset your dopamine with better sleep habitsIf you struggle with motivation, focus, or energy, this episode will give you the tools to break free from the exhaustion cycle and start thriving—physically, mentally, and spiritually.

AP correspondent Haya Panjwani reports on Blue Origin's experiment during spaceflight

This week the huns discuss their Hall(way) pass - think footballer and SAS. Hannah is still haunted to f**k - things got weird at Elephant and Castle underground station... The tarot reveals delusional traits and mysteries under a shiny blanket. We also get into Tchibo and how much we love the Scream movies. But enough of that. Would you like a story? Story One - a zombie tale about EMILY (no shade at all here). 'The Silence of the Fallen' narrated by Hannah. Story Two - 'You've got a new match' narrated by Big S. Will you ever use Tinder again? credit: Harbinger_51 C.o.w this week is a battle of the jingles - do we want the OG or the new COWCOWCOW? Creep of the Week is from AMY "The Mimics" narrated by Hannah. THANK YEW AMY HUN We finish by hexing Big Suze's herpes away - enjoy our gorjey huns!!!! xoxox JOIN OUR PATREON! EXTRA bonus episodes AND a monthly ghost hunt for just £4.50!  Or £6 for AD-FREE EPS and weekly AGONY HUNS! We'll solve your problems huns!  Sign up here: www.patreon.com/GhostHuns

It's a bird, it's a plane, it's Jemele Hill. Wait, no, that's Joy Taylor! Peanut Butter is at it again. In recent tweets and IG posts, Joy Taylor seems to think after pimping out women to sleezy broadcasters on Fox Sports, she's now a political savant. Critiquing Trump on his solution to the TikTok ban. Taylor's metamorphosis into Jemele Hill has begun. Whitlock gives advice to Joy Taylor, trying to show her the path of redemption through repentance. In other news, the Marcellus Wiley-Ryan Clark beef escalates to a new level, as Steve Kim and T.J. Moe comments on the back-and-forth exchange, as well as covering the trending sports topics of the day. Later we have a little Tennessee Harmony, as Kevin Donahue, Virgil Walker, and Anthony Walker join “Fearless” to discuss a woke Episcopal bishop attempting to lecture our 47th president, Donald Trump, on his deportation of illegal aliens. Spoiler alert: I'm pretty sure there is a secure border in heaven. Finally, to wrap up the show, Delano Squires makes his first appearance in 2025, presenting the unwarranted satire of MLK in the culture. An amazing show, jam-packed with everything you need to stay up to date. Tune in! We want to hear from the Fearless Army!! Join the conversation in the show chat, leave a comment or email Jason at FearlessBlazeShow@gmail.com Visit https://TheBlaze.com. Explore the all-new ad-free experience and see for yourself how we're standing up against suppression and prioritizing independent journalism. SHOW OUTLINE 00:00 Intro ​​Today's Sponsors: My Patriot Supply Right now, they're offering $50 off their 4-Week Food Kit. Go to https://PreparewithFearless.com now to grab yours. Preborn To donate, dial pound 250 & say the keyword “BABY” that's pound 250 “BABY” or donate securely at https://preborn.com/FEARLESS. Preborn has a one-hundred percent charity rating, so you can give with confidence.  Get 10% off Blaze swag by using code Fearless10 at https://shop.blazemedia.com/fearless Make yourself an official member of the “Fearless Army!” Support Conservative Voices! Subscribe to BlazeTV at https://get.blazetv.com/FEARLESS and get $20 off your yearly subscription. CLICK HERE to Subscribe to Jason Whitlock's YouTube: https://bit.ly/3jFL36G CLICK HERE to Listen to Jason Whitlock's podcast: https://apple.co/3zHaeLT CLICK HERE to Follow Jason Whitlock on Twitter: https://bit.ly/3hvSjiJ Learn more about your ad choices. Visit megaphone.fm/adchoices

Try Miracle at https://trymiracle.com/watcher Use promo code Watcher for an extra 20% off Try MeUndies at https://meundies.com/Watcher Use promo code Watcher for 20% off, plus free shipping Try Factor at https://factormeals.com/Watcher50 use code watcher50 to get 50% off your first box and 20% off your next month This week we ask the question, what if ghosts can only live 100 years! And give wedding advice! HOSTED BY Ryan Bergara & Shane Madej & Steven Lim PRODUCER & EDITOR--=-==-=--= Matt Real INTRO BY Anthony De Vera  EXECUTIVE PRODUCERS Steven Lim  Ryan Bergara Shane Madej Social: http://www.instagram.com/wearewatcher http://www.instagram.com/ryanbergara http://www.instagram.com/shanemadej http://www.instagram.com/stevenkwlim https://twitter.com/wearewatcher https://twitter.com/ryansbergara https://twitter.com/shanemadej https://twitter.com/stevenkwlim Business Inquiries:  hello@watcherentertainment.com Ask Watcher Pods! AskWatcherPods@gmail.com or leave a voicemail at (818)275-4585 Learn more about your ad choices. Visit megaphone.fm/adchoices

With Halloween right around the corner and Spooky Season in full-swing, Krista and Kurt look at one of the phenomena that spooks them the most…Mimics! Whether it's voices across the dark house from family members who aren't there, or friend's voices luring you into the woods, just what are these things? Are they ghosts? Are they Jinn? Are they just our imagination? And, as always, a taste-test!

Holmberg's Morning Sickness - Brady Report - Wednesday October 9, 2024 Learn more about your ad choices. Visit podcastchoices.com/adchoices

Christopher Eaddy, PhD, MBA is a renowned life coach, corporate trainer, and author, specializing in transforming both individuals and organizations. With a diverse background spanning government, law enforcement, education, healthcare, sales, and human resources, Christopher brings a wealth of experience and insight to his work. As a master life coach, he excels in areas such as communication, personal leadership, and overcoming barriers like stress and insomnia. His forthcoming book, "The Biology of Business: Why We Should Treat Our Businesses Like Our Bodies," encapsulates his unique approach to organizational health and efficiency.Episode Summary:In this engaging episode of "Transform Your Mind to Transform Your Life," host Myrna Young speaks with Dr. Christopher Eaddy about his soon-to-be-released book, "The Biology of Business: Why We Should Treat Our Businesses Like Our Bodies." Dr. Eaddy discusses the intriguing parallels between biological systems and organizational structures, suggesting that the health of a business can be managed much like the health of a human body.Drawing from his extensive background across diversified careers, Dr. Eaddy shares real-world examples of companies that succeeded by adopting biological principles such as homeostasis, adaptation, and feedback loops. He emphasizes the importance of understanding the interconnectedness of various systems within a business to ensure its survival and growth. From the critical role of leadership in maintaining the 'pulse' of an organization to the protective functions analogous to human skin, Dr. Eaddy provides actionable insights for leaders to foster a healthier, more resilient business.Key Takeaways:Bio-inspired Management: Companies can thrive by applying biological principles like homeostasis and adaptation to their organizational structures, ensuring all systems work harmoniously.Understanding Organizational 'Organs': Leadership, communication, and security structures in a business parallel vital organs and their functions in the human body, with interconnected systems crucial for overall health.Empathetic Leadership: Successful businesses often have leaders who engage empathically with employees, akin to how the body mobilizes resources to fight disease, leading to resilience and growth.Biological Audit: Conducting a comprehensive audit to assess the health of various business systems can preemptively identify and address issues, much like routine medical checkups for humans.Employee Well-being: Fostering an environment where employees feel comfortable providing honest feedback about their personal and professional stressors contributes to a healthier workplace ecosystem.See this video on The Transform Your Mind YouTube Channel https://www.youtube.com/@MyhelpsUs/videosTo see a transcripts of this audio as well as links to all the advertisers on the show page https://myhelps.us/Follow Transform Your Mind on Instagram https://www.instagram.com/myrnamyoung/Follow Transform Your mind on Facebookhttps://www.facebook.com/profile.php?id=100063738390977Please leave a rating and review on iTunes https://podcasts.apple.com/us/podcast/transform-your-mind/id1144973094