Podcasts about chitosan

Wanna know how the mountains of shrimp shells polluting our landfills could actually clean our water? Listen to this!More #water insights? Connect with me on Linkedin: https://www.linkedin.com/in/antoinewalter1/A big thanks to my sponsor, SimpleLab! https://gosimplelab.com/In short: CrustaTec is transforming shrimp shell waste into sustainable water treatment solutions. Using chitosan, a polymer extracted from shrimp shells, they've developed both a filter for textile dye removal and a natural flocculant for wastewater treatment that offers an eco-friendly alternative to traditional chemical treatments.#️⃣ All the Links Mentioned in this Episode #️⃣Crustatec's website: http://crustatec.com/Maria's LinkedIn: https://www.linkedin.com/in/amorinmariaisabel/The World Bank's Water Youth Innovation Challenge: https://blogs.worldbank.org/en/jobs/calling-youth-aquapreneurs-water-your-innovations-climate-crisisThe EAWAG's website: https://www.eawag.ch/en/

Federico y Teresa de la Cierva hablan con María Roberts, embajadora de Dyson en España por su línea Chitosan.

On this special edition episode, Amy Niver from Rosen's joins us to discuss Chitosan, a new biological addition to our Starting Line Soybean Seed Treatment.Watch the video version here: https://youtu.be/ao4bLCNp0VUFlip through the Merschman Seeds 2025 Product Guide to check out our Starting Line Soybean Seed Treatment, Enlist E3® Soybeans and PowerCore® Enlist® Corn hybrids and more: https://merschmanseeds.com/product-guideCheck out all of our social media links, website and more:https://linktr.ee/merschmanseeds

Watch the video version here: https://youtu.be/5G9P-DgBUJkOn this episode:

In this episode of The Common Sense MD, Dr. Rogers talks with Steve Nice, who is one of the masterminds behind DigestShield, about Chitosan and why it might just be the next big thing in health and wellness. From its origins to its many benefits, Steve shares his insights on how this powerhouse ingredient could be a game changer! This is a must listen! Check out our brand new online vitamin store: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/shop/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ What did you think of this episode of the podcast? Let us know by leaving a review! Connect with Performance Medicine! Sign up for our weekly newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/doctors-note-sign-up/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PMedicine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PerformancemedicineTN⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Performance Medicine⁠

In this week's episode we delve into the issues around filter and nozzle blockages. We pay particular attention to the problems that can arise when mixing various biological products and how to overcome them.   Fish-based organic fertiliser Most commonly extracted using phosphoric acid. Phosphorus often reacts with soluble calcium to form insoluble calcium phosphate. Once this forms, it isn't going anyway, no matter how much you rinse the system. So avoid calcium containing products when using fish-based fertiliser, or do a bucket test first. The other issue with many organic fertilisers, including those based on fish, is that they are commonly suspensions, not soluble concentrates. As such, if left for a long period of time in the spray tank they may settle out and form a layer along the bottom of the tank. Therefore, do not store diluted product overnight. Storing diluted biologicals is also never advised because it will stimulate microbial growth and the additional problems that come from that if not precisely controlled.   Molasses-based organic fertilisers When it comes to molasses it is the actual water you need to take care with. If you pour molasses quickly into very cold water it can sink to the bottom of the tank in one big solid lump! If that lump is sucked into a mixing pump it can cause a catastrophic failure. Therefore always add molasses slowly to any tank and agitate continuously. Alternatively, pre-dilute the molasses in some warm water before adding to the tank for further dilution to the spray concentration.    Seaweed extracts Confirm the pH first. Some are acidic, some neutral, but more commonly they are alkaline. If alkaline, avoid any product that will lower the pH and bring the carbohydrate (alginic acid etc) solids out of solution. Always avoid mixing with chitosan. As chitosan is acidic and cationic (seaweed extracts are anionic); any mix of these two will result in something with the appearance of vomit! If this doesn't happen, you are using poor quality seaweed extract and/or chitosan solution.   Humic and fulvic acid Humic acid solutions are very often moderately alkaline. So avoid any acidic product that will bring the pH down. If this happens you will get a thick tar coating your filters. We have seen a few cases recently of issues when tank mixing with citric acid. This has happened because farmers are now hearing that the efficacy of glyphosate (Roundup) can be increased by lowering the pH with citric acid. They are also hearing that the efficacy of glyphosate can be increased by the inclusion of humic or fulvic acids. So they have applied all three products to the spray tank and blockages have occurred.    Chitosan In addition to its use as a biostimulant and biofungicide, chitosan can also be used to remove contaminants from wastewater. Chitosan is used in waste water treatment because it binds to contaminants and takes them out of solution. So while removing bacteria, metal ions, and humic acid might be an advantage in that scenario, in a spray tank the opposite is true. Chitosan can be tank mixed with a variety of conventional agrochemicals and biologicals, but you need to do your homework first, and always conduct a bucket test with the dilution ratios and water you plan on using. If you need a small sample to do a tank mix with, then please get in touch. I always used to tell customers to never mix chitosan with silicon fertilisers, as these are alkaline and will also fall out of solution if mixed incorrectly. However, we have now developed a way of successfully tank mixing these products together by adjusting the pH of the solution after the addition of the silicon fertiliser. See our Fungicide Reduction Action Plan for more information.   Plant extracts It really depends on the type of extract, the pH and the purification as to how these will tank mix. A single chemical extract will stand a far greater chance of tank mixing than a crude extract (such as a cold-press ‘juice').   One example is yucca extract that contains natural soaps (saponins), these work best at pH above neutral. So if mixed with acidic co-applied products their efficacy may be diminished.  Amino acid biostimulants can also be derived from plant extracts (commonly from legumes). Other sources of amino acid biostimulants used in agriculture include fungal cultures, and the digestion of animal protein; particularly those sourced from pig's blood, bird feathers, and fish waste.  Amino acid biostimulants can have tank mixing issues with ALS inhibitor herbicides. This is because ALS inhibitor herbicides work by disrupting the synthesis of  amino acids in the weed. If you apply ample amino acids alongside the herbicide you could potentially negate the effect of the herbicide because the weed still has access to the amino acids that would otherwise be disrupted.   Nematodes Nematodes are notorious for blocking filters and spray nozzles. Nematodes are animals that are small enough to be delivered in water as a spray to the leaf surface. However, being animals, they are far larger than microbial biologicals, or suspension fertiliser particles and as such standard fitting filters and nozzles will block if nematodes are run through them. As such, research the filters and nozzles for optimum nematode deliver, and factor in the cost of these if you do not have them in stock at present. Nematodes are actually very close to being delivered by drone in the UK. The smaller volume applications or even dry applications that drones offer may suit nematode application better than conventional sprayers. Microbes When it comes to using microbial biologicals the first, and most obvious, tank mixing issue is that they should never be mixed with conventional chemical fungicides / bactericides. These pesticides act as biocides and will kill the beneficial microbes ithey are tank mixed with. In addition, many insecticides and herbicides might also have antimicrobial activity, so it is always best to check with the manufacturer before combining with microbials in the tank. Another consideration when using beneficial microbes is to the chlorine in tap water. While most farmers use water from tanks rather than tap water, a sizable proportion do use tap water; especially in periods of drought. If using tap water alongside microbials always add a dechlorinator first. Fungal biologicals Fungal biologicals include symbiotic mycorrhizae, free-living Trichoderma, and fungal biopesticides. Normally fungal biologicals are supplied from the manufacturers as either spores or ‘propagules'. Spores are usually

Autoimmun-Probleme? Entzündungs- oder Hormon-Troubles? Das (und leider vieles andere) kann an den heimtückischen PFAs liegen, „perfluorierten Alkylsubstanzen“. Das Zeug ist überall, in Lebensmitteln, Trinkwasser, Kleidung, Möbeln. Was du tun kannst, um dir zu helfen? Zuerst mal diesen Podcast hören.Eine vernünftige preisgünstige Edelstahltrinkflasche ist zum Beispiel diese.    Mariendistel kriegt man zum Beispiel hier. Bernd Stösslein und sein Kaffeeeinlauf: hier und hier.  Mehr zum auf Entgiftung spezialisierten Dr. Joachim Mutter hier.  Sein Buch „Lass dich nicht vergiften“ gibt es hier. Chitosan gibt es hier.   Akazienfaser gibt es hier. Den Lipo Glutathion Booster von Mitocare gibt es hier.   Niacin mit Flush gibt es hier. Zum Niacin-Entgiftungsprotokoll von Ron Hubbard (richtig, dem Scientology-Gründer, aber hat nix damit zu tun) geht es hier. Weil Andreas und Stefan so häufig gefragt werden, welche Produkte sie selbst verwenden, haben sie gemeinsam mit Julia Tulipan eine Seite eingerichtet, auf der sie ihre persönlichen Lieblingsprodukte (und aktuelle Rabattcodes) sammeln.Das Buch „Ab jetzt Biohacking“ von Andreas Breitfeld und Stefan Wagner erschien am 17. Mai beim Ecowing-Verlag. Bestellen kann man es hier.Das Buch „Viel Erfolg beim Misserfolg“ ist der Biohacking-Business-Ratgeber von Stefan Wagner, erschienen im Seifert Verlag, erhältlich hier.Andreas Breitfelds Website.Das ausführliche Porträt über Andreas Breitfeld in The Red Bulletin (Autor, übrigens: Stefan Wagner).Das Biohacking-Special, das Andreas Breitfeld und Stefan Wagner gemeinsam für The Red Bulletin INNOVATOR produziert haben.Stefan Wagners Biohacking-Kolumne im „carpe diem“.

Powdery mildew affects every type of crop on the farm (except Christmas TREES!). However, the type of mildew that affects each species is different. That means you cannot get cross-infection between crops or weeds. Mildew thrives in warm humid conditions, but actually doesn't like being sprayed with water!   We talk about how to prevent powdery mildew and control methods for when you have a crop that is starting to become infected. If you are currently suffering from powdery mildew, check out Eutrema's bio-fungicide Chitosan.

Puccinia, or to me and you, RUST! A serious problem for arable farmers, especially if it hits early in the growing season. We discuss the very unusual biology of the many species of rust that infect cereal crops. Plus we discuss some very novel methods of control. Not least Eutrema's CHITOSAN bio-fungicide. For more information on one of these, please visit: https://eutrema.co.uk/shop/pesticides-organic/chitosan/  

The Maltento insect farm started as a small, test-scale operation in a home bathroom in Craighall Park, Johannesburg. Almost seven years later, founder and CEO Dean Smorenburg has seen the operation evolve into a fully-fledged business based in Epping, Cape Town. Smorenburg says his decision to pivot from management consulting to insect farming stems from his interest in sustainability. Insect farming, and to be more specific, fly farming, is no longer new or novel, with this biotech sector rapidly gaining traction globally. Smorenburg's take on the industry is to not call Maltento a waste management company, as some fly farmers tend to do. This means he doesn't want to use the legions of black soldier flies (BSFs) at Maltento to feed on unwanted waste, such as abattoir leftovers. Instead, his goal is to create a consistently high-quality product, which means Maltento's livestock must have a consistently high-quality diet. "We have a PhD looking after the diet of the insects to make sure we produce good-quality products throughout," says Smorenburg. This philosophy sees Maltento's livestock flourish on a diet which includes spent grains from breweries, as well as ground-up rusks. Larvae are typically harvested at day 11 or 12. The Epping facility - which started out at 1 600 m2 and has since expanded to 5 500 m2 - produces whole dried fly larvae for the backyard chicken and wild-bird markets, mainly in the US. It also produces a product called Digest or Palate+ from dehydrated larvae, which is a high-protein flavourant or palatant used to coat dry pet kibble to enhance the overall feed experience. "In taste tests, dogs choose our product over other products," says Smorenburg. "Of course, we also have to make sure that their human owners like the smell." Digest is sold mainly in South Africa, but trials are ongoing in the US and Europe to expand Maltento's market. A second focus for the company is the aquaculture market, with trials currently on the go in various African markets, as well as the US. Here the Digest product is added to fish feed, especially on trout farms. "With a 3% inclusion of our product we have seen the fish gain weight, while there is also a drop in the mortality rate," says Smorenburg. "Aquaculture is definitely a big opportunity for us going forward." Another opportunity on the horizon is the production of chitosan, although this may take longer to develop. Chitosan is a sugar that comes from the outer skeleton of shellfish, including crab, lobster and shrimp - as well as fly larvae. It's used in a number of industries, from the pharmaceutical sector to cosmetic production. Here, Maltento will target the cosmetics industry first, says Smorenburg. "Our long-term view is to unlock the BSF's value in its totality." In order to accommodate Maltento's plans, the Epping facility will have to expand yet again, this time to around to 7 000 m2. The urban farm has two arms - the production of sellable product, as well as the breeding of new livestock. Maltento currently rolls out 75 t of product a month, and aims to double that to 150 t a month next year. "We are currently in the early commercialisation phase," notes Smorenburg. "Ultimately, we want to have multiple plants, near large feed sources, which will reduce our carbon footprint and our input costs." This could mean an expansion to Gauteng, for example, as well as the rest of Africa. Maltento employs 65 people.

Explore the fascinating world of Military Medicine research and ethics with our special guest, retired Army Nurse Corps Colonel Dr. Laura Brosch. As the Assistant Vice President of Research Initiatives and Compliance at the Uniformed Services University of the Health Sciences, Dr. Brosch shares her journey into Military Medicine and experiences developing ethical protocols for conducting research in combat theaters. From the development of Theater Clinical Practice Guidelines to the introduction of novel treatment modalities for combat casualty care, you'll gain incredible insight into the challenges and advancements in Military Medicine. Discover how the Special Medical Augmentation Response Team (SMART) and the military's use of Investigational New Drugs (INDs) are crucial in modern Military Medicine. Dr. Brosch discusses the importance of regulatory compliance when administering these drugs and highlights the advancements in surgical products like combat gauze, Chitosan powder, and much more. Learn how these products were safely fielded in high OP TEMPO environments and understand the unique challenges faced when setting up a research capability in theater. Join us as we delve into the Joint Trauma System and the Theater Clinical Practice Guidelines developed under Colonel Paul Cordts' guidance. Dr. Brosch shares the ethical considerations taken into account when deciding which protocols to implement, such as DVT prophylaxis, tourniquet use, hypothermia prevention, and concussion awareness. Hear about the challenges of collecting data in the chaos of combat and the processes used to obtain DOD-required waivers and approvals for hospital trauma research. This conversation offers a unique perspective on the complex ethical considerations of conducting medical research in the military. Don't miss this enlightening discussion! Chapters: (0:00:00) - Military Medicine Research and Ethics (0:10:11) - Medical Research in Theater (0:26:40) - Trauma Research Guidelines and Waivers (0:41:14) - Military Medical Research and Ethics   Chapter Summaries: (0:00:00) - Military Medicine Research and Ethics (10 Minutes) We speak with Dr. Laura Brosch, a retired Army Nurse Corps Colonel and Assistant Vice President of Research Initiatives and Compliance at the Uniformed Services University of the Health Sciences. We discuss her pathway into Military Medicine and how she became the nursing research consultant to the Surgeon General. She shares how the Medical Research And Material Command played an early role in OAF and OEF, and how a plan was developed to ethically conduct research in combat theaters. Laura also explains how Theater Clinical Practice Guidelines were developed and how they've evolved over the past 20 years, and how the military brings novel treatment modalities for combat casualty care to the battlefield.   (0:10:11) - Medical Research in Theater (16 Minutes) Dr Laura Brosch and I discussed the Special Medical Augmentation Response Team (SMART) and the military's use of Investigational New Drugs (INDs). We explored the responsibility of SMART and the importance of regulatory compliance when administering these drugs. We also examined the advancements made in surgical products like combat gauze, Chitosan powder, and other products, and how they were safely fielded in a high OP TEMPO environment. Lastly, we talked about the need to set up a research capability in theater and the unique challenges this presented.   (0:26:40) - Trauma Research Guidelines and Waivers (15 Minutes) We discuss the Joint Trauma System and the Theater Clinical Practice Guidelines they developed, Colonel Paul Cordts' involvement in bringing these guidelines to life, and the ethical considerations taken into account when deciding which protocols to implement. Specific protocols such as DVT prophylaxis, tourniquet use, hypothermia prevention, and concussion awareness are discussed. The challenges of collecting data in the chaos of combat and the processes used to obtain DOD-required waivers and approvals for hospital trauma research are also discussed.   (0:41:14) - Military Medical Research and Ethics (7 Minutes) We talk with Dr Laura Brosch about the complex ethical considerations of conducting medical research. We explore the protocol she developed to allow the use of investigational products in the event of combat casualties. We discuss the regulation changes and how our research community has become more sophisticated. We also discuss the special rules for military service regarding research protections, and Laura shares her experiences as Assistant Vice President of Research Initiatives and Compliance at the Uniformed Services University of the Health Sciences. Finally, we reflect on her contributions to Military Medicine and the importance of ethical conduct in research.   Episode Keywords: Military Medicine, Research Ethics, Army Nurse Corps, Uniformed Services University, SMART, Investigational New Drugs, Combat Gauze, Chitosan Powder, Joint Trauma System, Theater Clinical Practice Guidelines, DVT Prophylaxis, Tourniquet Use, Hypothermia Prevention, Concussion Awareness, Regulatory Compliance, Research Capability, DOD Waivers, Research Protections Hashtags: #wardocs #military #medicine #podcast #MilitaryMedicine #CombatCasualtyCare #ResearchEthics #SMARTteam #InvestigationalNewDrugs #SurgicalAdvancements #JointTraumaSystem #CombatMedicine #Research   Honoring the Legacy and Preserving the History of Military Medicine   The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation.   Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/episodes   Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all Military Medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield, demonstrating dedication to the medical care of fellow comrades in arms.     Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast

This is a MUST listen show where Doug and Kevin have the privilege to speak with Mark Nichols from Organisan Corporation. Mark discusses and explains his all natural product O2-YS. This is a natural surfactant made from Chitosan and Yucca that has amazing benefits to not only turf but all botanical species. Mark's knowledge and vast experience is infectious and our conversation will pump you up for the 2023 season! Instagram turf_nutrition_mangmt_podcast⁠ Doug Gray: Instagram @turf_trade dgray@theturftrade.com www.theturftrade.com Kevin Salters: Instagram @rootdevelopmentllc Facebook Root Development LLC Mark Nichols www.02yscorp.com http://www.organisancorp.com markn@organisancorp.com Spraye.io CRM systems for the turf manager of any size https://spraye.io The Landscaping Bookkeeper- https://www.gulfcoastbk.com Sheila Chaplin, CFP® Reliable Tax & Business Services-screliabletax@gmail.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/rootdevelopmentllc/message

Wie Chitosangewinnung auf biotechnologischem Weg ökologisch und nachhaltig gelingt. Chitosan ist eine wertvolle Substanz mit vielen guten Eigenschaften, zb wirkt sie antibakteriell und fungizid. Das macht sie interessant für verschiedenste Bereiche, etwa wird sie in der Trinkwasseraufbereitung verwendet oder in der Produktion von Kosmetika und Medizinprodukten. Chitosan hilft, eingearbeitet in Lebensmittelverpackungen, Foodwaste vorzubeugen, da das Biopolymer die Haltbarkeit der Lebensmittel verlängert. Und auch im Pflanzenschutz kann Chitosan gegen bestimmte Pilze und Bakterien wirken - als biologischer Schädlingsbekämpfer. Der große Wermutstropfen an Chitosan: Der übliche Gewinnungsprozess ist ressourcenaufwändig, wenig ökologisch und Schalentiere müssen dabei sterben. Molekularbiologin Sabine Gruber vom Studiengang Bioengineering an der FH Campus Wien hat in mehreren von der FFG geförderten Forschungsprojekten mit Pilzen als Basis von Chitosan große Erfolge erzielt. Im aktuellen Forschungsprojekt stehen Insekten als Grundlage im Fokus. 

Schüttelinkubator, Electrospinning, Autoklav und Sterilbank - Mit seinen besonderen Apparaturen hebt sich das BioLab der Burg von den restlichen Werkstätten wie Holz, Metall und Keramik ab. In Folge 59 des Hurra Hurra Podcast sprechen die beiden Mitarbeiter des Labs, Johann Bauerfeind und Dr. Falko Matthes, mit Christian Zöllner darüber, welche Möglichkeiten Studierenden dort offenstehen. Außerdem geben sie Einblicke in ihre eigene Forschung zur Verarbeitung von Chitosan, zur Verbindung lebendiger Prozesse und Organismen mit industriellen Fertigungstechniken und berichten über die Vernetzungsarbeit des Labs über die Grenzen der Hochschule hinaus.

Researchers Otago University may have found us an option for food packaging that doesn't involve harmful plastics. It's called Chitosan, and it's a material derived from the outer shells of crustaceans. Combined with essential oils it's proven to be durable and safe, and can even protect perishable food from light, temperature and water vapour. University of Otago Associate Professor Azam Ali talks to Jesse about their work so far.

ChitogenX Inc (CSE:CHGX) CEO Philippe Deschamps joined Proactive's Stephen Gunnion with details of the company's plans to pursue sales of medical-grade chitosan as a new near-term commercial revenue initiative following the completion of an internal commercial and regulatory readiness process. Deschamps telling Proactive that the company has a low-cost optimized GMP manufacturing process for the chitosan portion of its ORTHO-R product at its disposal and is ready to pursue additional commercial initiatives such as the sale of medical-grade chitosan. #ProactiveInvestors #ChitogenX #chitosan #ORTHO-R #CSE

I speak with Craig Kasberg of Tidal Vision and Tony Sun of GC Ventures about biopolymers, applications chitosan, building and investing in science-based startups. (0:47) Biopolymers (1:37) Chitosan (3:05) Tidal Vision's manufacturing (4:46) Applications and markets – water treatment, textiles, agriculture (8:29) Tidal Vision's progress as a company (9:55) Challenges while building a company (12:20) Future of Tidal Vision (13:53) GC Ventures and why Tony invested in Tidal Vision (15:19) Investment criteria and decision making (17:25) Duration of due diligence (18:00) Investing in deep tech during economic downturns

00:00 - Intro00:27 - What is a clarifier?01:28 - What is chitosan?04:38 - What does CE-Clarifier do?06:08 - How to use CE-Clarifier09:23 - Frequently asked questions11:49 - Summary. Thanks for listening! ------------------------------------Connect with Orenda TechnologiesWebsite: https://www.orendatech.comBlog: https://blog.orendatech.comYouTube: https://www.youtube.com/user/OrendaTechnologiesFacebook: https://www.facebook.com/orendatech/Instagram: https://www.instagram.com/orendatechnologies/Swim Across America | Team Orenda: https://www.swimacrossamerica.org/goto/orenda

I have been experimenting with Chitosan, which is one of the more unique supplements out there Along with weight loss, it may also help with sleep, mold detoxification, and blood sugar regulation If you have never looked into Chitosan, this episode is worth listening through Notes: Chitosan Self Hacked: https://selfhacked.com/blog/chitosan/ Chitogauze: https://www.amazon.com/HemCon-ChitoGauze-Bleeding-Bandage-Dressing/dp/B07TN2Q89X/ref=sr_1_7?dchild=1&keywords=chitosan+bandage&qid=1620075220&sr=8-7#customerReviews Effect of chitosan on renal function in patients with chronic renal failure: https://pubmed.ncbi.nlm.nih.gov/9255718/ Chitosan and Vitamin A: https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.12831 Study in Rats against BPA: http://impactfactor.org/PDF/IJPCR/6/IJPCR,Vol6,Issue4,Article4.pdf Chitosan For Diabetes: https://www.sciencedirect.com/science/article/abs/pii/S0144861720307682 Chitin Wiki: https://en.wikipedia.org/wiki/Chitin Chitosan Wiki: https://en.wikipedia.org/wiki/Chitosan Chinese Medicine Kidney Health: https://rootsofhealthsc.com/traditional-chinese-medicine-and-kidney-health/ Rats Given Rheumatoid Arthritis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665683/ Products: Powdered Chitosan: https://amzn.to/33wdCtS Liposan Ultra Chitosan: https://amzn.to/3haB48j QUAX WEBSITE: http://www.quaxpodcast.com QUAX YOUTUBE: https://www.youtube.com/channel/UCtXpRH1DhwWwxoIivprk7ww TWITTER: https://twitter.com/QuaxPod FACEBOOK: https://www.facebook.com/Quax-Podcast-105724194245591 Music by Jenny Jahlee from Live at KBOO

Ehab takes us on a journey through organic products for making pesticides and herbicides and how the Government is mandating farms to go organic, providing a big scaling opportunity for Chitosan. He also talks about the power of great leadership and the right team, enjoy!

One thing that you may not know is that Natural Chemistry and SeaKlear now have the same parent company. Since SeaKlear is the premiere clarifier it makes sense to highlight this product of the NC brand clarifier. I go over when to use a clarifier with Alicia Stevens who the education and training manager at Natural Chemistry. Part 1: Overview of Enzymes, Phosphate Removers and Clarifiers:  https://www.buzzsprout.com/110832/8053638Part 2: Pool Perfect Max with Alicia Stevens of Natural Chemistry: https://www.buzzsprout.com/110832/8053687Part 3: Phosfree Max & Phosfree with Alicia Stevens of Natural Chemistry: https://www.buzzsprout.com/110832/8053752Part 4: Water clarifier-SeaKlear Chitosan Clarifier with Alicia Stevens of Natural Chemistry: https://www.buzzsprout.com/110832/8053887Part 5: Natural Chemistry Trade Grade Products with Sales Director Chris Marcano: https://www.buzzsprout.com/110832/8053931Leslie's Pro: Pool Service Pro, open a Wholesale account today! Customer referrals, free cleaner repairs, free water testing, open 7-days a week. It is fast and easy to become a Leslie's Preferred Pool Care Provider. https://lesliespool.com/commercial-services.html/?utm_medium=referral&utm_source=spll&utm_campaign=spll

Allison London Brown, CEO of UVision360, Inc. in North Carolina, discusses the Luminelle DTx Hysteroscopy System. Traditionally, these procedures are conducted in a hospital or ambulatory setting. But the Luminelle system is compact and designed to be used in the doctor's office, and the company is expected to file an application with the FDA that will allow doctors to conduct the first visual hysteroscope biopsy outside a hospital setting. This technology will help to fill an unmet medical need brought on by the COVID pandemic. Allison London Brown has 20+ years of diverse medical device, consumer and pharmaceutical experience in Healthcare. During her career, she has launched over 90 products/services, and has served as an advisor to CEOs, Corporate Boards, NGO’s, non-profits, and government organizations. She has led product pipeline, strategy, and fundraising initiatives for these organizations. Ms. London Brown leads UVision 360, Inc., focused on development of the LUMINELLE DTx Hysteroscopy System, a new all-in-one, office-based hysteroscopy system. She also serves as a Senior Advisor/Board Member for several early and later stage start-ups in the Research Triangle Park, NC. Previously, she co-founded Aegis Women’s Health Technologies, focused on prevention of Urinary Tract Infection, an early-stage medical device start-up in RTP. And most recently served as Global Vice President of Marketing, Medical Education and Training for Bioventus, a global leader in Orthobiologics. She was employed by Johnson & Johnson for 10 yrs. in R&D, operations, strategic marketing, and sales leadership roles within multiple divisions. She served as General Manager of the Maternal Fetal Care Division of GE Healthcare, VP of Corporate Strategy & Communications at Healthways, and Chief Operating/Commercial Officer of Stanley Healthcare Solutions, a healthcare technology company and division of Stanley/Black & Decker, facilitating and implementing a $274MM HC technology acquisition. Ms. London Brown graduated from Auburn University in Textile Sciences, concentrating in Medical Textiles. She earned her Master of Science Degree at North Carolina State University, in Polymer Chemistry, where she extensively researched the healing properties of Chitosan. In addition, Ms. London Brown earned an MBA from Temple University, Fox School of Business. She is the author of three publications, co-inventor of six issued patents, and speak

Eduardo Longoria (@Portunus17) is the Co-Founder of Portunus Biotechnologies. He graduated from UT Austin Eduardo and has taken part in the building of a non-profit laboratory; Prophase Biostudios. Having an interest in Biomaterials, Eduardo conducted the research that led to the first product of Portunus Biotechnologies; Chitosan for green crop protection. Eduardo continues to research biomaterials as part of his master’s degree at the Federal University of Parana (UFPR). Part of this research is the development of a chitosan hydrogel mask that acts as a detection tool for COVID19. Now with Portunus Biotechnologies securely installed in the Toledo Biopark; Eduardo and his partners are endeavoring to bring their Chitosan to market and continue developing novel and green solutions to agricultural problems.

The Gary Null Show is here to inform you on the best news in health, healing, the environment.   How adding green tea extract to prepared foods may reduce the risk for norovirus In study, edible coating made with tea extract killed the virus and bacteria Ohio State University, July 22, 2020   Infusing prepared foods with an edible coating that contains green tea extract may lower consumers' chances of catching the highly contagious norovirus by eating contaminated food, new research suggests. Norovirus, which causes vomiting and diarrhea, sickens an estimated 48 million people in the United States every year and causes about 3,000 deaths. It's transmitted from person to person and through consumption of contaminated water and food. Lots of things we consume contain what are known in the industry as edible films: They can enhance appearance, like wax that makes apples shiny; hold contents together, like plastic drug capsules; and prevent contents from seeping together by, for example, being placed between a prepared pie crust and the filling. "In many cases, an edible film is in a product, but you are not aware of it," said Melvin Pascall, professor of food science and technology at The Ohio State University and senior study author. "We don't have to put that on the label since the material is edible. That's another way in which we use packaging - and the consumer doesn't have to know." Some edible films are also enriched with antimicrobial agents that can kill or slow the growth of organisms that cause illness, such as E. coli and mold. In this new study led by Pascall, adding green tea extract to a film-forming substance created a safe-to-eat barrier that killed norovirus as well as two types of bacteria. While most antimicrobial packaging advances to date have emphasized fighting bacteria, this finding holds promise for a newer area of research into the concept of using edible film to kill a virus, Pascall said. "Norovirus is a tough virus to work with - it is a non-enveloped virus, which is the type more resistant to sanitizers and antimicrobial agents," he said. "However, because it has public health concerns and has been implicated in a number of foodborne outbreaks, we wanted to look at the effects of green tea extract on norovirus." The study is published in the International Journal of Food Science. Pascall and his team created the films with a base substance called chitosan, a sugar found in the exoskeleton of shellfish. Chitosan is marketed as a weight-loss supplement and used in agricultural and medicinal applications, and has been studied extensively as a safe and readily available compound for edible film development. Previous studies have suggested that chitosan has antimicrobial properties. But norovirus might exceed its bug-fighting abilities: In this study, the researchers found that chitosan by itself did not kill the virus. To test the effects of green tea extract, the researchers dissolved it alone in water and added it to a chitosan-based liquid solution and dried film. Several different concentrations of the extract showed effectiveness against norovirus cells, with the highest level tested in this study killing them all in a day. "We had tested the chitosan by itself and it didn't show much antimicrobial activity against the virus," Pascall said. "But when we added the green tea extract to chitosan, we saw that the film had antiviral properties - so we concluded the antiviral properties were coming from the green tea extract." The scientists introduced at least 1 million virus cells to the solution and dried films. Those containing green tea extract lowered the presence of virus cells within three hours. The films with the highest concentration of green tea extract reduced norovirus to undetectable levels by 24 hours after the exposure. Though norovirus was the focus of this work, the researchers also found that green tea extract lowered E. coli K12 and listeria innocua, surrogates for bacteria that also cause foodborne illness, to undetectable levels within 24 hours. This study didn't identify how the killing happens - typically an antimicrobial agent disables organisms in ways that cause them to die or render them unable to reproduce. The researchers used mouse norovirus cells because human norovirus cells don't grow well in a lab setting. There is still a lot of work to do before green tea extract-infused films are ready to enter the market. A tricky part of adding natural substances to edible packaging is ensuring that enough is used to deliver the microbe-killing effect without changing the taste or smell of the food. "A higher concentration of a natural antimicrobial might cause a large drop in the target organism, but at the same time it defeats the purpose of the food by adding an objectionable taste or odor," Pascall said. "There is also the impact of the natural compound on the material itself - it may cause the film to become too brittle or sticky. These are things food scientists have to consider when using antimicrobial agents, especially those from natural sources." It's also too soon to tell which kinds of food would be the best candidates for antiviral edible films made with green tea extract. It depends on whether the food would be exposed to heat, moisture or acidic conditions, for example. There is also a chance another natural substance could do an even better job - Pascall is conducting similar studies with other extracts.       The brain-boosting potential of tart cherry juice University of Delaware, July 21, 2020   A recent study by scientists from the University of Delaware (UD) has found that drinking cherry juice has beneficial effects on memory. Published in the journal Food & Nutrition, it demonstrated that drinking Montmorency tart cherry juice every day for 12 weeks improved cognitive function in adults aged 65 to 80. Tart cherry juice supplementation can improve cognitive performance in older adults Lead author Chai Sheau Ching and colleagues had previously observed the beneficial effects of tart cherry antioxidants, such as melanin, melatonin and anthocyanin, on high blood pressure and cholesterol. In particular, the team found that drinking juice made from Montmorency tart cherries, the most common cherries in the U.S., helped reduce systolic blood pressure, fight inflammation and neutralize the harmful effects of oxidative stress. Based on these earlier findings, the team speculated that the antioxidants in tart cherries could also exert neuroprotective effects on the brain and improve cognitive abilities in older adults. To test their hypothesis, the team asked 37 adults, aged between 65 and 80, to drink either 16 ounces of Montmorency tart cherry juice or a placebo drink of the same amount every day – one in the morning and one in the evening – for 12 weeks. The team also asked the participants to maintain their diet and record their food consumption for the duration of the trial. None of the participants had prior diagnoses of medical conditions like diabetes, heart disease, stroke, cancer and neurological disorders at the time of the trial. Neither were they taking medications that might affect their cognitive abilities. To see whether or not the cherry juice had any effect on the participant's cognitive abilities, the team had each participant answer a series of questionnaires and tests before and after the trial period. At the end of the experiment, the researchers found that the participants in the tart cherry group scored higher in the tests that measured subjective memory, episodic visual memory and spatial memory than the participants in the placebo group. Compared with their pre-trial test results, the tart cherry group also experienced a four percent reduction in their movement time – the time it takes to complete a task – in the post-trial cognitive tests. In addition, the tart cherry group had a 23 percent reduction in errors in episodic visual memory. In both the pre- and post-trial cognitive tests, the participants in the tart cherry group scored significantly higher than those in the placebo group. These findings suggest that the antioxidants in tart cherries are behind the juice's beneficial effects on cognition. Chai hopes that future studies can shed more light on the molecular mechanisms underlying the cognitive-enhancing effects of Montmorency tart cherries. Cognitive health and aging Commenting on their findings, Chai noted that cognitive health plays a key role in determining the quality of life of older adults. According to recent reports by the World Health Organization, about 50 million people around the globe suffer from some form of dementia. And every year, 10 million cases are added to this figure. (Related: Adding more dietary choline can cut back the risk of dementia.) Dementia is a major cause of disability and dependency among older adults. Despite the fact that dementia is not a natural part of aging, its symptoms, including forgetfulness and difficulty communicating, are usually felt later in life. Fortunately, an emerging body of evidence suggests that proper diet and nutrition can reduce the risk of dementia and neurodegenerative diseases in old age. For instance, people can incorporate Montmorency tart cherry juice into a well-balanced diet to enhance their brain performance.     Study suggests benefit for vitamin C in endometriosis Zhejiang University (China), July 20, 2020   According to news reporting originating in Hangzhou, People's Republic of China, research stated, “Endometriosis is a common disease in females that seriously affects quality of life. The principal pathological process of endometriosis is pelvic inflammation, and local and peripheral fibrosis.” The news reporters obtained a quote from the research from Zhejiang University, “Treatment of endometriosis requires both pharmacological and surgical approaches. Vitamin C can scavenge oxygen free radicals and thus accelerate repair of damaged endometrium. This aim of this study was to investigate whether vitamin C can reduce fibrosis in endometriotic lesions. After establishing a rat model of endometriosis, vitamin C solution (vitamin C group) or physiological saline solution (control group) was injected into the abdominal cavity. We compared the indices of fibrotic endometriotic lesions between the two groups. The volume of endometriotic lesions and degree of fibrosis observed in rats within the vitamin C group was significantly reduced compared with those observed in the control group. Immunohistochemistry showed that transforming growth factor-beta 1 (TGF-beta 1), connective tissue growth factor (CTGF), alpha-SMA, and collagen type I staining in lesions of the vitamin C group was significantly less than that observed in lesions from the control group (P < 0.05). Quantitative, real-time PCR (RT-PCR) determined that relative mRNA expression levels of TGF-beta 1, CTGF, alpha-SMA, and collagen type I in lesions obtained from the vitamin C group were significantly lower than levels measured in lesions obtained from animals in the control group. Vitamin C can reduce the volume of endometriotic lesions and inhibit fibrosis of lesions in rats.” According to the news reporters, the research concluded: “This study supports the use of vitamin C in the treatment of endometriosis.”     Cannabis Appears Safe And Effective At Treating Chronic Pain, New Clinical Trial Shows University of California Irvine, July 21, 2020   Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. Donald Abrams of UC San Francisco. The findings appear in JAMA Network Open. “These trial results show that vaporized cannabis appears to be generally safe,” said Gupta, a professor of medicine on the faculty of UCI's Center for the Study of Cannabis. “They also suggest that sickle cell patients may be able to mitigate their pain with cannabis – and that cannabis might help society address the public health crisis related to opioids. Of course, we still need larger studies with more participants to give us a better picture of how cannabis could benefit people with chronic pain.” Opioids are currently the primary treatment for the chronic and acute pain caused by sickle cell disease. But the rise in opioid-associated deaths has prompted physicians to prescribe them less frequently, leaving sickle cell patients with fewer options. The double-blind, placebo-controlled, randomized trial was the first to employ such gold-standard methods to assess cannabis's potential for pain alleviation in people with sickle cell disease. The cannabis used in the trial was obtained from the National Institute on Drug Abuse – part of the National Institutes of Health – and contained equal parts of THC and CBD. “Pain causes many people to turn to cannabis and is, in fact, the top reason that people cite for seeking cannabis from dispensaries,” Gupta said. “We don't know if all forms of cannabis products will have a similar effect on chronic pain. Vaporized cannabis, which we employed, may be safer than other forms because lower amounts reach the body's circulation. This trial opens the door for testing different forms of medical cannabis to treat chronic pain.”   Twenty-three patients with sickle cell disease-related pain completed the trial, inhaling vaporized cannabis or a vaporized placebo during two five-day inpatient sessions that were separated by at least 30 days. This allowed them to act as their own control group. Researchers assessed participants' pain levels throughout the treatment period and found that the effectiveness of cannabis appeared to increase over time. As the five-day study period progressed, subjects reported that pain interfered less and less with activities, including walking and sleeping, and there was a statistically significant drop in how much pain affected their mood. Although pain levels were generally lower in patients given cannabis than in those given the placebo, the difference was not statistically significant.     Bad eating habits may cause blindness, warn researchers University of Bristol (UK), July 20, 2020   There's no denying that eating junk food is bad for your health, as it's linked to obesity and an increased risk of various health problems. A report in the Annals of Internal Medicine even found that a diet full of junk food could eventually cause vision loss. Researchers from the University of Bristol in the U.K. looked at a particular case involving a teenager who was a “fussy eater” and didn't eat anything except junk food. Several years of following an unhealthy diet eventually made him lose his eyesight. This unusual and shocking case highlights the dangers of an unhealthy diet. It can cause obesity and increase your risk of developing heart disease and cancer. The report also found that consuming junk food may “permanently damage the nervous system, particularly vision.” The adverse effects of poor eating habits The teen first experienced problems when he was 14, and he consulted a doctor due to symptoms like tiredness. His blood tests then revealed that he had anemia. Since the teenager had B12 deficiency, he was also treated with injections of the vitamin. His physician then told him to improve his eating habits. When the teenager turned 15, he reported more issues like hearing loss and vision problems. His physicians were baffled because the results from an MRI and eye exam were all normal. (Related: Cut the junk: Eating junk food can give you food allergies.) After two years, the teenager's vision worsened. At 17, an eye test revealed that his vision was 20/200 in both eyes: The threshold for being considered “legally blind” in America. Results from other tests revealed that the teenager also suffered damage to his optic nerve, the bundle of nerve fibers that connects the back of the eye to the brain. Despite being told to improve his eating habits when he was 14, the teenager still had a vitamin B12 deficiency. Worse, he also had low levels of copper, selenium and vitamin D. The physicians were alarmed at these deficiencies. After questioning the teenager, they found out that he didn't like eating “certain textures of food.” Since elementary school, the patient followed a limited diet that consisted only of foods such as: Chips Fries Processed ham slices Sausage White bread Once the doctors ruled out other possible causes for his vision loss, the patient was diagnosed with nutritional optic neuropathy or damage to the optic nerve because of nutritional deficiencies. The researchers noted that “[purely] dietary causes are rare in developed countries.” Most of the time, nutritional optic neuropathy is caused by alcohol abuse, drugs, poor diet or the malabsorption of food. Early detection can potentially reverse vision loss due to nutritional optic neuropathy. But unfortunately for the teenager, by the time his condition was diagnosed, his vision loss was permanent. Dr. Denize Atan, a senior lecturer in ophthalmology at Bristol Medical School and a co-author of the study, explained that eyeglasses wouldn't help the patient's vision since any damage to the optic nerve can't be addressed with lenses. To prevent his vision loss from worsening, physicians prescribed the teenager nutritional supplements. Avoidant-restrictive food intake disorder and mental health The doctors involved in the patient's case also referred him to mental health services for an eating disorder because there seemed to be more to his unusual diet. Unlike kids who were simply picky eaters, the teenager's diet “was very restrictive and caused multiple nutritional deficiencies.” They believe that the teenager might have a condition called “avoidant-restrictive food intake disorder” (ARFID). This relatively new diagnosis, previously called “selective eating disorder,” may cause a lack of interest in food or avoidance of foods with certain colors, textures or other factors without links to the patient's body weight or shape. Other symptoms of ARFID include: Abdominal pain, cold intolerance, constipation, lethargy or excess energy Dramatic restriction in amount or types of food eaten Dramatic weight loss Eating only certain textures of food Eating a limited range of preferred foods that becomes narrower over time or picky eating that worsens with time Fears of choking or vomiting Inconsistent and vague gastrointestinal issues, like an upset stomach, around mealtimes with no known cause No body image disturbance or fear of weight gain ARFID often manifests in childhood, and patients tend to have a normal body mass index (BMI) like the teenaged boy, concluded the study authors.   Chronic inflammation alters the evolution of cells in the colon, study finds Researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers Cambridge University and Wellcome Sanger Institute, July 21, 2020   In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level. Researchers from the Wellcome Sanger Institute and Cambridge University Hospitals found that the rate of DNA change within colon cells affected by IBD was more than double that in healthy colon, increasing the likelihood of these cells gaining DNA changes that could lead to cancer. The study, published today (21 July) in Cell, also found that chronic inflammation associated with IBD disrupts the tissue structure of the colon, allowing cells to expand over an abnormally wide area. The results provide valuable insights into evolution within the body, and the development of IBD and colorectal cancers. IBD primarily refers to ulcerative colitis and Crohn's disease, chronic illnesses characterised by inflammation of the digestive system that can be highly disruptive to a patient's quality of life. Between 1990 and 2017, the number of IBD cases worldwide rose from 3.7 million to 6.8 million*. The causes of the disease remain unknown, though it is thought that inflammation occurs as a result of an inappropriate immune response to gut microbes. People suffering from IBD are at an increased risk of developing gastrointestinal cancers compared to the general population. Patients will undergo regular surveillance for this and may, in some cases, opt to undergo surgery to remove their entire colon in order to mitigate this risk. In this new study, clinicians at Addenbrooke's Hospital, Cambridge provided colon tissue samples donated by 46 IBD patients, along with anonymised information about their medical history and treatment. Researchers at the Wellcome Sanger Institute then used laser-capture microdissection to cut out 446 individual crypts, the tiny cavities that make up colon tissue, so they could be whole-genome sequenced. These sequences were analysed to discover the mutation rate in the tissue, the genetic relationship between crypts and any genes that were more mutated than normal. They were then compared to sequences from 412 crypts from 41 individuals without IBD, so that the effects of chronic inflammation on the DNA sequence could be observed. The team found that there were more than twice as many DNA changes in the diseased tissue than in normal, and the longer the duration of the disease, the greater this excess. The study also uncovered evidence of an evolutionary process whereby mutations in particular genes are under positive selection. Some of these positively-selected mutations were enriched in genes associated with colorectal cancers, shedding light on the link between IBD and certain cancers. The researchers also detected evidence of positive selection of mutations in genes associated with immune system regulation in the gut and the ability of the cells to fend off the bacteria resident in the colon. Sigurgeir Olafsson, first author of the study from the Wellcome Sanger Institute, said: "How our bodies continue to evolve during our lifetime is a fundamental part of our biology. It has been fascinating to study the effect of a chronic disease on this process and uncover evidence that changes in the genetic sequence of gut cells could have a direct role in the onset of inflammatory bowel disease." Dr Tim Raine, clinical lead for the inflammatory bowel disease (IBD) service at Addenbrooke's Hospital, Cambridge and Honorary Faculty member at the Wellcome Sanger Institute, said: "Colorectal cancer is one of the main clinical concerns when treating patients with IBD. In this study, we found that normal mutational processes that are operative in us all are accelerated in the IBD affected gut, leading to a more than two-fold increase in the rate at which some gut cells acquire mutations, and this underpins the increased cancer risk in IBD." Dr Peter Campbell, an author on the study from the Wellcome Sanger Institute, said: "The role of somatic mutations in cancer susceptibility has long been appreciated. It is exciting to see the methods that we and others have used to understand cancers now being applied to other common diseases. These approaches have given us unique insights into the effects of inflammatory bowel disease on the DNA sequence of the inflamed tissue." A previously unexplained observation in IBD is that repeated flares of inflammation tend to affect the same patch of tissue, suggesting some permanent alterations to the colon. These findings highlight genetic mutations as a possible explanation, with some positively-selected mutations in immune regulation genes occurring in the same regions of the bowel affected by chronic inflammation. Dr Carl Anderson, lead author of the study from the Wellcome Sanger Institute, said: "We know that DNA changes contribute to the development of cancer, but their role in common non-cancerous diseases like inflammatory bowel disease (IBD) has not been extensively studied. Our study revealed that somatic changes in the DNA sequence of the cells that line our gut may contribute to the development of IBD. I strongly believe that studying somatic mutations in all common diseases, not just IBD and cancers, has the potential to provide novel insights into disease biology and highlight potential drug targets."   Studies suggest a fasting diet could boost breast cancer therapy A USC-led team of international scientists found that a one-two punch of a fasting diet with hormone therapy may enhance the effects of breast cancer treatment  University of Southern California, July 22, 2020   A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans. In studies on mice and in two small breast cancer clinical trials, researchers at USC and the IFOM Cancer Institute in Milan -- in collaboration with the University of Genova -- found that the fasting-mimicking diet reduces blood insulin, insulin-like growth factor 1 (IGF1) and leptin. In mice, these effects appear to increase the power of the cancer hormone drugs tamoxifen and fulvestrant and delay any resistance to them. The results from 36 women treated with the hormone therapy and fasting-mimicking diet are promising, but researchers say it is still too early to determine whether the effects will be confirmed in large-scale clinical trials. The research was published in the journal Nature. "Our new study suggests that a fasting-mimicking diet together with endocrine therapy for breast cancer has the potential to not only shrink tumors but also reverse resistant tumors in mice," said Valter Longo, the study's co-senior author and the director of the Longevity Institute at the USC Leonard Davis School of Gerontology and professor of biological sciences at the USC Dornsife College of Letters, Arts and Sciences. "We have data that for the first time suggests that a fasting-mimicking diet works by changing at least three different factors: IGF1, leptin and insulin." The researchers say the two small clinical trials are feasibility studies that showed promising results, but they are in no way conclusive. They believe the results support further clinical studies of a fasting-mimicking diet used in combination with endocrine therapy in hormone-receptor-positive breast cancer. The scientists also contributed to a recent clinical study of 129 breast cancer patients conducted with the University of Leiden. The results, published last month in Nature Communications, appeared to show increased efficacy of chemotherapy in patients receiving a combination of chemotherapy and a fasting-mimicking diet. In the two new small clinical trials -- one of which was directed by the study co-corresponding author Alessio Nencioni -- patients with hormone-receptor-positive breast cancer receiving estrogen therapy along with cycles of a fasting-mimicking diet seemed to experience metabolic changes similar to those observed in mice. These changes included a reduction in insulin, leptin and IGF1 levels, with the last two remaining low for extended periods. In mice, these long-lasting effects are associated with long-term anti-cancer activity, so further studies in humans is needed. "Some patients followed monthly cycles of the fasting-mimicking diet for almost two years without any problems, suggesting that it is a well-tolerated intervention," Nencioni said. "We hope this means that this nutritional program that mimics fasting could one day represent a weapon to better fight cancer in patients receiving hormone therapy without serious side effects." "The results in mice are very promising. And the early clinical results show potential as well, but now we need to see it work in a 300- to 400-patient trial," Longo explained. The data also suggest that in mice, the fasting-mimicking diet appears to prevent tamoxifen-induced endometrial hyperplasia, a condition in which the endometrium (or the lining of the uterus) becomes abnormally thick. The study authors believe this potential use of the fasting diet should be explored further, given the prevalence of this side effect of tamoxifen and the limited options for preventing it. Approximately 80% of all breast cancers express estrogen and/or progesterone receptors. The most common forms of hormone therapy for these breast cancers work by blocking hormones from attaching to receptors on cancer cells or by decreasing the body's hormone production. Endocrine therapy is frequently effective in these hormone-receptor-positive tumors, but the long-term benefits are often hindered by treatment resistance. Several clinical trials, including one at USC on breast cancer and prostate patients, are now investigating the effects of the fasting-mimicking diets in combination with different cancer-fighting drugs. "I like to call it the nontoxic wildcard for cancer treatment," Longo said. "These clinical studies we have just published -- together with the many animal studies published in the past 12 years -- suggest that cycles of the fasting-mimicking diet has the potential to make standard therapy more effective against different cancers, each time by changing a different factor or nutrient important for cancer cell survival."   Scientists identify 10 risk factors for Alzheimer disease Fudan University (China), July 17, 2020   Alzheimer's disease may be preventable by keeping an eye on key factors including weight gain, blood pressure and avoiding stress, experts say. Researchers said many risk factors are modifiable in the fight to prevent dementia, which affects around 850,000 people in the UK, two-thirds of whom have Alzheimer's. Their review of existing studies found 10 risk factors had strong evidence of a link with Alzheimer's, and people could take action to avoid them. These included ensuring good education in early life, keeping the brain active through activities such as reading, and not being overweight or obese in later life. People should also avoid depression, stress, high blood pressure, head trauma and diabetes to reduce their risk, they said. Other factors had weaker links that could be adjusted, including not being obese in midlife, taking exercise, getting enough sleep, including vitamin C in the diet and not smoking. The study, published in the Journal of Neurology, Neurosurgery & Psychiatry, was led by Professor Jin-Tai Yu at Fudan University in China. The researchers gathered 395 studies and came up with a list of factors that could be used by doctors to try to prevent Alzheimer's disease. They said research into preventing dementia should continue but their report offered “clinicians and stakeholders an evidence-based guideline for Alzheimer's disease prevention”. Fiona Carragher, director of research and influencing at the Alzheimer's Society, said: “In recent years, research has suggested that nearly a third of dementia cases may be preventable and this review builds on this idea, specifically in relation to Alzheimer's disease and how certain risk factors, many of which are associated with cardiovascular health, may be within our control. “We need a deeper dive into each of these risk factors to understand how they work together on an individual level and how best to support people to manage them. “This review demonstrates that, while observational studies are useful to help identify potential risk factors, we need to see many more interventional trials to understand what the best approaches are to preventing Alzheimer's disease developing in the first place. “We don't have all the answers yet, but we do know that small steps to improving your physical and mental health can make a big difference, like walking to your local shop for milk instead of jumping in the car.”

über einen möglichen Weg, Covid-19 zu bekämpfen. Mit einer vergleichsweise simplen Herangehensweise ist Joe Bender davon überzeugt, das Coronavirus weitgehend eindämmen zu können. Problem: Die Regierung ignoriert bislang den Projektentwurf, der letztendlich Leben retten kann.

Bueno bueno bueno, en esta ocasión comenzamos una nueva sección que titulamos ... Seguir leyendo88. Desmontando el chitosan La entrada 88. Desmontando el chitosan se publicó primero en Mykdiet.

Training: Insanity and Results!Motivation: Time Management and your success!Nutrition: Weight Loss Pill ingredients, helpful or harmful? QuickFit Club update, thanks for the great response, after last podcast! The free membership will be around at least another month (or two) so get going and do those workouts!  Please do the survey so I can know what you like and don't like and we can make changes before the official launch!MOTIVATIONHere are a few of the top time management tips you can put into practice.Tip #1 - Delegate Tasks - It's easy as a mom to take on every task yourself. This is only going to stress yourself. Take time to delegate some of those tasks to give yourself a break and free yourself to do more important things.Tip #2 - Create a To-do List - Every day, it's a good idea to create a to-do list for that day. This way you know what needs to be accomplished. Looking at the list will help you remember what you must do and as you check things off the list, it will keep you motivated to keep on going. Tip #3 - Plan for the Next Day - At the end of every day, it can be very helpful to plan for the next day. Figure out a schedule of tasks so you can put things to rest when you go to bed.Tip #4 - Organize Your Work Space - If you do any work at home, make sure that you are keeping your work space organized. If you keep things together and have a place for everything, you'll find it is easier to take care of business within your home. These are just a few of the top tips for those who need help with time management. Start implementing these tips into your life and you'll see a huge difference in the time you have available and all that you accomplish.NUTRITIONLooking for help with losing weight? Help that goes beyond the usual lifestyle changes, portion control advice and exercise routines? Weight-loss supplements touting names like "fat burner" and "thermo max" can be enticing. But do they work? And even more important, are they safe?Here's some info on a few of the most popular ingredients currently in supplements for weight loss.ChitosanMade from the shells of lobsters, shrimp and other shellfish, chitosan is an indigestible fiber. It is supposed to help weight loss by binding with the fat you eat, blocking its absorption. However, studies do not support this claim. Side effects include constipation and gas. People with shellfish allergies should beware.ChromiumMost often present as chromium picolinate, it has been promoted to boost lean mass and decrease body fat. Though study findings have been inconclusive, an analysis of several studies recently concluded that supplementing with 200 to 400 micrograms of chromium picolinate could result in about a 2.5-pound weight loss per week in some people. Other studies have found a loss of body fat and an increase in muscle tissue, with no change in weight. Still others have found no effect at all. Though some laboratory studies have raised safety issues, a large number of human studies suggest it is safe.Citrus Aurantium (Bitter Orange)This herbal extract is a natural source of synephrine (a compound similar to ephedrine) and the supplement industry's current answer to the ephedra ban. But there are no published studies to show it is an effective supplement for weight loss. And like ephedra, its side effects include an increase in blood pressure; Environmental Nutrition recommends avoiding it.Conjugated Linoleic Acid (CLA)Both animal and human research hints at a possible role for CLA in reducing body fat and increasing lean body mass, but it's not quite ready for prime time. None of the human studies have been long-term. CLA is currently being studied in combination with chromium picolinate. CLA is found naturally in dairy foods and beef and is generally considered safe.Garcinia CambogiaThe extract from Garcinia cambogia fruit rind contains hydroxycitric acid (HCA), which supposedly curbs food intake, weight gain and storage of excess calories as fat. However, studies have failed to prove G. cambogia is an effective weight-loss aid. The most common side effects are upper respiratory and gastrointestinal symptoms.GuaranaCaffeine is the effective ingredient in guarana plant seeds. Guarana may have a mild appetite suppressant effect over the short term. It was often used in combination with ephedra until ephedra was banned. The potential side effects are those of caffeine overdoseóinsomnia, restlessness, anxiety or panic.TRAININGThe Definition of Insanity is doing the same thing over and over and expecting different results. Is this true for you and your fitness program? “Making a mistake once is called learning. Making it twice means you’re not learning.”  Be prepared! Put spare gym clothes and old sneakers in the trunk just in case! Get all the most recent episodes on iTunes or download this episode here: Fit 215: Insanity and Results! Weight Loss Pill ingredients, helpful or harmful? Time Management and Your Success!

For this episode, join Caitlin Carmody and Meghan McGillin as these two friends summarize some of the most recent and fascinating literature in Food Microbiology.This month, for our 9th episode, our speakers walk us through the general outlines of these two new papers and also masterfully articulate the ways in which these findings connect to what currently is practiced within the field of Food Microbiology. Caitlin and Meghan look into the use of CRISPRSeroSeq as a method for Salmonella serotype identification. This method allows for rapid and specific identification of low abundance serovars within a sample, which could revolutionize the surveillance of foodborne pathogens. This technology has the potential to increase the response rate and traceback of foodborne outbreaks of the most common foodborne disease-causing pathogen in the United States. This month we even had the pleasure of interviewing Assistant Professor at Gettysburg College, Dr. Nikki Shariat, who is one of the authors of our first paper! Dr. Shariat has a strong background in Salmonella and is currently utilizing it to develop CRISPR-based molecular tools for Salmonella surveillance. Our second paper outlines the exciting new potential of incorporating bacteriophages into chitosan-based edible films as an alternative method for biocontrol in food packaging. The paired antimicrobial properties of bacteriophages and chitosan address the issues of plastic waste in the food industry without compromising on food safety! [[If you have a moment, be sure to rate us 5 stars. It might seem silly, but those ratings help our group to get more attention and to spread new literature to those of us too busy to sit down and comb through the primary literature. If you have any questions or comments, or if you have a suggestion on how we might make our podcast even better - feel free to leave a comment with your thoughts or email us at "foodmicrominutes@gmail.com".]] Here at F.M.M., we believe in open communication as a way of highlighting the massive benefits of collaboration between scientists. Thanks for listening!

Dave Arnold is back for a short show this week to answer listener questions including fungal Chitosan clarification, alcoholic Pacojet sorbets, and chopping candied rose petals. Later on Dave discusses the best techniques for searing with the Searzall (Searzall Searzall) and explains the science behind eutectic freezing. This program was brought to you by Fairway Market.

Mon, 13 Dec 2010 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/12475/ https://edoc.ub.uni-muenchen.de/12475/1/Neunhoeffer_Anna_Katharina.pdf Neunhoeffer, Anna Katharina ddc