Podcasts about Ovarian cancer

Cancer originating in or on the ovary

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Best podcasts about Ovarian cancer

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Latest podcast episodes about Ovarian cancer

Best Of The Bay
iHeart Radio Communities June 28

Best Of The Bay

Play Episode Listen Later Jun 27, 2025 30:01 Transcription Available


Ovarian Cancer Awareness Month isn't until September, but on June 28th Gild Radner would've turned 79. Gilda's Clubs nationwide are using the date to bring national attention to a disease that affects over 19,000 women every year in our country. Kristian White, Vice President of Gilda's Club South Florida. The saying is ‘It's a Man's World' - but glass ceilings have been being shattered for generations, by groundbreaking women. Kelly Ramsey - author of: Wildfire Days: A Woman, a Hotshot Crew, and the Burning American West.

Best Of The Bay
Ovarian Cancer Awareness and Fighting Wildfires

Best Of The Bay

Play Episode Listen Later Jun 27, 2025 30:01 Transcription Available


Ovarian Cancer Awareness Month isn't until September, but on June 28th Gild Radner would've turned 79. Gilda's Clubs nationwide are using the date to bring national attention to a disease that affects over 19,000 women every year in our country. Kristian White, Vice President of Gilda's Club South Florida. The saying is ‘It's a Man's World' - but glass ceilings have been being shattered for generations, by groundbreaking women. Kelly Ramsey - author of: Wildfire Days: A Woman, a Hotshot Crew, and the Burning American West.

pharmaphorum Podcast
IMUNON at ASCO 2025: Changing the micro-tumour environment in advanced ovarian cancer

pharmaphorum Podcast

Play Episode Listen Later Jun 17, 2025 14:14


Onsite at ASCO 2025 in Chicago, web editor Nicole Raleigh sat down with Dr Stacy Lindborg, CEO of IMUNON, to discuss the company's oral presentation at the Congress from the Phase 2 OVATION 2 study of IMNN-001, an IL-12 immunotherapy, in women with newly diagnosed advanced ovarian cancer – since published in the peer-reviewed journal Gynecologic Oncology today. Dr Lindborg shares her journey to her present role, the true potential shown in this new data for addressing unmet needs in advanced ovarian cancer, and the oncological space – and ASCO 2025 itself – more generally. You can also listen to episode 185a of the pharmaphorum podcast in the player below, download the episode to your computer, or find it - and subscribe to the rest of the series – on Apple Podcasts, Spotify, Overcast, Pocket Casts, Podbean, and pretty much wherever else you download your other podcasts from.

Two Onc Docs
Ovarian Cancer 2025 UPDATE

Two Onc Docs

Play Episode Listen Later Jun 16, 2025 12:58


This week's episode will be focusing on Ovarian Cancer with 2025 updates since we last covered this topic in 2022. We will go over all important details on the risk factors, presentation, diagnosis, staging & treatment options for both localized and metastatic disease. 

Johns Hopkins Kimmel Cancer Center Podcasts
Cancer Matters with Dr Bill Nelson - Biomolecular Engineering Research

Johns Hopkins Kimmel Cancer Center Podcasts

Play Episode Listen Later Jun 12, 2025 14:30


Dr Bill Nelson talks with Dr Denis Wirtz about his research using CODA, an artificial intelligence platform, to identify and analyze pre-cancerous lesions previously undetected in the pancreas and along the fallopian tubes.

Help and Hope Happen Here
Jennifer Vertentes started her HERO PACKAGE FOUNDATION after being inspired by meeting 3 year old Emerson Lucier at Hasbro Children's Hospital where she was being treated for Acute Myeloid Leukemia.

Help and Hope Happen Here

Play Episode Listen Later Jun 9, 2025 55:07


Jennifer Vertentes was a police officer in Providence Rhode Island when she decided to go to Hasbro Children's Hospital on Thanksgiving Day of 2018 to meet kids who had to spend their Thanksgiving being treated for different reasons, including being treated for Pediatric Cancer. While she was there she met 3 year old Emerson Lucier who was going through her 3rd battle with Acute Myeloid Leukemia . This meeting inspired Jennifer to start her HERO PACKAGE FOUNDATION to help put a smile on the faces of these kids who were battling these difficult diseases. Jennifer, who in 2023 had to retire from the Police Department after suffering an injury while trying to save a person who was drowning, was also diagnosed with Ovarian Cancer that year. Fortunately for the Pediatric Cancer community, she continues to help these kids as she deals with her disease, that fortunately was diagnosed at a very early stage. 

Cancer Freedom Podcast
Episode 132: Ovarian Cancer to Cancer Free (w Special Guest Ana Arias)

Cancer Freedom Podcast

Play Episode Listen Later Jun 3, 2025 35:45


Get the same amazing support that Ana received!  Apply to join the Cancer Freedom Program Click HERE: www.cancerfreedomprogram.com ‘When I walked out of chemo I was totally terrified.  Was this it?” That's a quote from stage 3 ovarian cancer survivor, Ana Arias.  After being diagnosed at the age of 35, Ana knew that chemotherapy and surgery were going to be difficult but manageable.  As she went through chemo, she began to feel secure in having an ongoing defence against cancer. But when those chemo cycles came to an end - the uncertainty and fear started creeping in.  In this episode of the Cancer Freedom Podcast, Ana, shares how she navigated her cancer recovery and what allowed her to be on a path to being the healthiest she has ever been.   PS - Whenever you are ready, here the 2 best ways I can help you -  1) “Your A-Z Guide to Staying Cancer Free” **FREE** Click here: https://dramycancer.com/azcancerfree 2)Join the Cancer Freedom Program  Click HERE: www.cancerfreedomprogram.com   ***Let's Connect: Website: www.cancerfreedomprogram.com YouTube: https://www.youtube.com/channel/UCUt9...  

Oncotarget
Blocking PRDX1 Protein May Improve Chemotherapy Response in Ovarian Cancer

Oncotarget

Play Episode Listen Later Jun 3, 2025 4:10


BUFFALO, NY - June 3, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on May 19, 2025, titled “PRDX1 protects ATM from arsenite-induced proteotoxicity and maintains its stability during DNA damage signaling." In this study, led by first author Reem Ali and corresponding author Dindial Ramotar from Hamad Bin Khalifa University in Qatar, researchers discovered that a protein called PRDX1 helps maintain the stability of ATM, a key protein involved in repairing damaged DNA, especially when cells are under stress from arsenite exposure. The study found that without PRDX1, cells lose their ability to repair DNA and become more sensitive to chemotherapy. This finding suggests that targeting PRDX1 could improve the success of some cancer treatments. PRDX1 is already known for its role in protecting cells from oxidative damage, but this study shows it also plays a role in the DNA repair process. ATM is an essential protein that detects breaks in DNA and starts the repair process. When PRDX1 is missing, ATM is rapidly lost, especially when cells are exposed to arsenite, a toxic substance found in the environment. Without ATM, the DNA repair system fails, leaving cells more vulnerable to damage. By using both human cell lines and clinical samples from ovarian cancer patients, the team showed that high levels of PRDX1, along with ATM and MRE11 (another DNA repair protein), were linked to tumors' aggressive features and lower patient survival rates. This pattern suggests that tumors with high PRDX1 may resist chemotherapy by increasing their DNA repair capacity. On the other hand, removing PRDX1 weakened the repair system and made cancer cells more responsive to DNA-damaging platinum drugs. The study also showed that combining low doses of arsenite with drugs that either block ATM or damage DNA caused a much higher rate of cancer cell death in cells that lacked PRDX1. These results suggest a new treatment approach: lowering PRDX1 levels to make cancer cells more sensitive to DNA-damaging platinum therapies already in use. This highlights PRDX1 not only as a protector of cell function but also as a potential weak point in cancer cells. “As such, we propose that small molecule inhibitors of PRDX1, or single nucleotide polymorphisms that compromise PRDX1 function, in combination with low doses of arsenite can be exploited to treat chemo-resistant tumours.” These findings open the door for the use of PRDX1 as a biomarker to predict treatment response and as a promising target for new combination therapies. For patients with ovarian cancer and potentially other tumors, adjusting PRDX1 levels may help overcome drug resistance and improve outcomes. DOI - https://doi.org/10.18632/oncotarget.28720 Correspondence to: Dindial Ramotar - dramotar@hbku.edu.qa Video short - https://www.youtube.com/watch?v=suOhF7mPlNQ Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28720 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, redox signaling, homologous recombination, protein interaction, cell cycle, protein modification To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Grief Out Loud
When Death Is Scheduled – Mark Chesnut On Grieving His Sister

Grief Out Loud

Play Episode Listen Later Jun 2, 2025 39:30


In this deeply personal episode, Mark Chesnut returns to Grief Out Loud to share his experience of losing his sister Glynn to ovarian cancer. Glynn chose medical aid in dying after nearly four years of treatment, giving Mark and his family the unusual experience of knowing when death would occur. This conversation explores the complexity of "scheduled death," the challenges of finding appropriate language to discuss medical aid in dying, and how knowing the date changed their family's grieving process. Mark Chesnut is a journalist, editor, public speaker, and the author of: Prepare for Departure.  Mark previously appeared on Grief Out Loud in October 2022, discussing caring for his mother at the end of her life. Mark lives in New York City with his husband Angel and recently wrote an article about his sister's experience with medical aid in dying.  This episode is the second in our 2025 three-part series highlighting the voices of communities who have historically been underrepresented in the grief world. The series is part of an ongoing collaboration between Dougy Center and The New York Life Foundation. We are deeply grateful for New York Life Foundation's tireless support and advocacy for children and teens who are grieving. Grief Out Loud is a production of Dougy Center, the National Grief Center for Children and Families in Portland, Oregon.

Oncology Peer Review On-The-Go
S1 Ep163: Spotlighting Key Upcoming Presentations Across Oncology at ASCO 2025

Oncology Peer Review On-The-Go

Play Episode Listen Later May 26, 2025 10:42


Ahead of the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, CancerNetwork® spoke with a variety of oncology experts about the late-breaking abstracts, plenary sessions, and other key presentations that may shift the paradigm across different cancer care fields. They highlighted anticipated clinical trial results that may transform the standard of care for gynecologic malignancies, lung cancer, and other disease types. Rachel N. Grisham, MD, section head of Ovarian Cancer and director of Gynecologic Medical Oncology at MSK Westchester of Memorial Sloan Kettering Cancer Center, shared her anticipation of findings from the phase 3 ROSELLA trial (NCT05257408) assessing relacorilant plus nab-paclitaxel in patients with platinum-resistant ovarian cancer. She stated she was excited to see if the data may represent a new opportunity for this patient population. Next, MinhTri Nguyen, MD, a medical oncologist and hematologist at Stanford Health Care, highlighted a few breast cancer presentations to look out for. These topics included a plenary session on data from the phase 3 SERENA-6 study (NCT04964934) evaluating camizestrant in combination with CDK4/6 inhibitors for those with hormone receptor–positive, HER2-negative advanced breast cancer harboring emergent ESR1 mutations. Additionally, Eric K. Singhi, MD, assistant professor in the Department of General Oncology in the Division of Cancer Medicine, and assistant professor in the Department of Thoracic/Head and Neck Medical Oncology at The University of Texas MD Anderson Cancer Center, spoke about a range of potentially practice-changing results in the lung cancer field. For example, he described a session focused on primary results of the phase 3 IMforte trial (NCT05091567) assessing lurbinectedin (Zepzelca) plus atezolizumab (Tecentriq) for those with extensive-stage small cell lung cancer (ES-SCLC). According to Singhi, data from IMforte may shift the paradigm of maintenance therapy for this SCLC population. In the world of head and neck cancer, Douglas R. Adkins, MD, associate professor of Internal Medicine, Division of Oncology, Section of Medical Oncology at Washington University School of Medicine in St. Louis, Missouri, highlighted the session on the phase 3 NIVOPOSTOP GORTEC 2018-01 trial (NCT03576417). Investigators of this study evaluated nivolumab (Opdivo) in combination with chemoradiotherapy for those with resected head and neck squamous cell carcinoma. Adkins noted his excitement to see how these data may impact the standard of care, particularly for patients in Europe, where investigators conducted the study. As part of an Oncology Decoded discussion, Benjamin Garmezy, MD, the associate director of genitourinary research and executive cochair of the Genitourinary Cancer Research Executive Committee at Sarah Cannon Research Institute (SCRI) and medical oncologist at SCRI Oncology Partners specializing in genitourinary cancers, discussed key abstracts in bladder cancer. One specific presentation included additional findings from the phase 3 NIAGARA trial (NCT03732677), which may show how circulating tumor DNA can influence treatment decision-making regarding perioperative durvalumab (Imfinzi) for patients with muscle-invasive bladder cancer.

BioCentury This Week
Ep. 296 - Trends in Obesity, Vinay Prasad at FDA, Ovarian Cancer Insights

BioCentury This Week

Play Episode Listen Later May 13, 2025 33:10


Biopharmas developing therapies for obesity are looking to a future where the quality of weight loss matters as much as the quantity — what targets and programs could help realize that vision? On the latest BioCentury This Week podcast, BioCentury's editors discuss the signaling pathways that may exclusively target fat mass while preserving, or even increasing, lean mass — and which companies are playing in the space.The editors also assess what Vinay Prasad's past comments say about how he might lead FDA's Center for Biologics Evaluation and Research (CBER) — and examine how investors are evaluating the possibility that he might move the bar for regulatory approvals. The team then introduces the first in a new BioCentury series, with a look at a Literature Dive into ovarian cancer “atlases” — large-scale molecular profiling studies that point to predictive signatures and patient stratification strategies. This episode was sponsored by Jeito Capital.View full story: https://www.biocentury.com/article/655898#biotech #biopharma #pharma #obesity #FDA #CBER #LifeScience #OvarianCancer00:01 - Sponsor Message: Jeito Capital03:22 - Obesity: Quality over Quantity15:47 - Prasad at FDA27:58 - Ovarian Cancer AtlasesTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text

Research To Practice | Oncology Videos
Gynecologic Cancers — Fourth Annual National General Medical Oncology Summit

Research To Practice | Oncology Videos

Play Episode Listen Later May 11, 2025 48:42


Featuring perspectives from Dr David M O'Malley and Dr Brian M Slomovitz, including the following topics: Ovarian Cancer; HER2-Directed Therapy for Advanced Gynecologic Cancers — Dr O'Malley (0:00) Endometrial Cancer and Cervical Cancer — Dr Slomovitz (23:38) CME information and select publications

What Your Therapist Is Reading ®
Unlucky Lori: A Raw and Unfiltered Look at One Woman's Battle with Ovarian Cancer and How HOPE Wins

What Your Therapist Is Reading ®

Play Episode Listen Later May 7, 2025 31:20


Trigger Warning for todays episode as we are discussing cancer diagnosis, treatments, and the potential impact of these experiences on individuals and families. After today's episode, head on over to @therapybookspodcast to learn about our latest giveaway. *Information shared on this podcast is for information and eductional purposes only. In this weeks episode, Jessica Fowler speaks with Lori Elliot Sacks about her book Unlucky Lori: A Raw and Unfiltered Look at One Woman's Battle with Ovarian Cancer and How HOPE Wins.  In this book, Lori shares her journal of over almost a decade about her experience of going through treatment for Ovarian Cancer and then also being diagnosed with Parkinson's Disease. In this episode, listen is as Lori shares about the difficult times and how she has coped to continue to live a life she wants. She shares examples of ways she could take control in times that it could be difficult.  Lori shares her excitement for life and love of her family, while managing her own struggles through her illness.  Take a listen as Lori shares the insights that have helped her along the way.  About the author: Lori Elliot Sacks: Trouble free and flying high- was Lucky Lori!  I have been a Hospice Nurse, a Therapist, and a Psychiatric Nurse Practitioner. However, the role of patient and ovarian warrior continues to challenge me daily . It demands patience and positivity. This memoir is intense-BEWARE.. but full of HOPE and GRATITUDE.    

Bench to Bedside
Cracking the Code: Research Sheds New Light on Ovarian Cancer Biomarker

Bench to Bedside

Play Episode Listen Later May 7, 2025 18:08


In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with Dr. Rebecca Whelan, an associate professor of chemistry at the University of Kansas and member of KU Cancer Center's Cancer Biology research program. The discussion focuses on the limitations of the CA125 blood test for ovarian cancer detection and Dr. Whelan's groundbreaking research, which reveals new insights into the structure of the CA125 protein. Dr. Whelan explains how new DNA sequencing technologies and artificial intelligence, specifically the Alpha Fold program, have helped her team improve the understanding and detection of ovarian cancer. Additionally, Dr. Whelan talks about collaborative efforts to identify new biomarkers for early diagnosis of ovarian cancer and shares advice for young scientists interested in making a difference in medicine through chemistry. Do you have questions about cancer? Call our Bench to Bedside Hotline at (913) 588-3880 or email us at benchtobedside@kumc.edu, and your comment or question may be shared on an upcoming episode! If you appreciated this episode, please share, rate, subscribe and leave a review. To ensure you get our latest updates, For the latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. Links from this Episode: Learn more about Dr. Whelan's research into CA125 Learn more about ovarian cancer  Read about ovarian cancer screening and diagnosis at KU Cancer Center Learn more about Dr. Rebecca Whelan

Born to Heal Podcast with Dr. Katie Deming
How a Cancer Patient's 30 Day Water Fast Led to a Spiritual Awakening with Donna DiPane and Oncologist Dr. Jason Konner | EP 93

Born to Heal Podcast with Dr. Katie Deming

Play Episode Listen Later May 6, 2025 64:26 Transcription Available


Download Your Free Webinar & Ultimate Guide to Water Fasting to Heal Cancer and Chronic Illness https://www.katiedeming.com/prolonged-water-fasting/How would your life transform during a 30-day water fast?Dr. Katie Deming is joined by her client Donna DiPane and medical oncologist Dr. Jason Konner from Memorial Sloan Kettering Cancer Center to share an extraordinary healing journey. Donna recently completed a 30-day supervised water-only fast as part of her holistic approach to healing from ovarian cancer. What makes this story especially powerful is the collaborative relationship between conventional and holistic medicine.Chapters:00:17:00 – The fear wasn't just about cancer00:22:00 – I unzipped from my body00:31:00 – A message from God at 3 am00:38:00 – When the shell started to crack00:52:00 – Strip it all down to healThey explore how fasting goes far beyond physical detoxification. Donna shares the profound spiritual awakening she experienced, including receiving powerful messages during the night, connecting with her "light body," and finding a deep release from the fear that had dominated much of her life. Dr. Konner offers his perspective as a conventional oncologist, describing his initial concerns about safety and his surprise at witnessing Donna's transformation throughout the process - not just physically, but emotionally and spiritually.Listen and learn about what happens during a fast, from the physical challenges of the first week to the emotional and spiritual openings that can occur as the body and mind clear.Disclaimer: Never attempt prolonged fasting without proper medical oversight as it can be dangerous. Send us a text with your question (include your phone number)Join Dr. Katie at CANCER: FROM FEAR TO HOPE on May 8, 2025https://heal.regfox.com/heal-from-fear-to-hopeCode: KATIERESILIENCE10 Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatie MORE FROM KATIE DEMING M.D. Download Your Free Webinar & Ultimate Guide to Water Fasting to Heal Cancer and Chronic Illness https://www.katiedeming.com/prolonged-water-fasting/6 Pillars of Healing Cancer Workshop Series - Click Here to EnrollWork with Dr. Katie: www.katiedeming.comFollow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Take a Deeper Dive into Your Healing Journey: Dr. Katie Deming's Linkedin Here Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER:The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose...

Dear Infertility: Finding Calm When Trying Is Trying
Ectopic Pregnancy, Egg Quality After 35, & an Ovarian Cancer Breakthrough

Dear Infertility: Finding Calm When Trying Is Trying

Play Episode Listen Later May 6, 2025 38:55


In this episode of From First Period to Last Period, Sarah bravely recounts her ectopic pregnancy — a harrowing experience that included a ruptured fallopian tube and uterus — and how it ultimately inspired her to pursue a career in nursing. Kristyn and ⁠Dr. Jenna Kahn⁠ answer some of your most pressing fertility questions: I'm in my late 30s — how can I improve my egg quality for IVF or natural conception? And what's the real deal with fertility supplements — are they worth it, or just wishful thinking?In breakthrough news, we discuss a promising new blood test for early detection of ovarian cancer — a disease that's often caught too late. Could this innovation change the game for survival rates?Plus, a quick but essential guide to cancer screenings: how to recognize early signs of ovarian cancer, when to get a mammogram, and the latest pap smear guidelines you should know.Hit play now on ⁠Spotify⁠, ⁠Apple Podcasts⁠, ⁠YouTube⁠, or wherever you listen!

Overlooked: A podcast about ovarian cancer
What is cancer survivorship, with Teresa Arthur

Overlooked: A podcast about ovarian cancer

Play Episode Listen Later May 6, 2025 24:24


What does it mean to survive a diagnosis, and live with cancer? For this episode, we return to the subject that launched the very first season of Overlooked: ovarian cancer, with Teresa Arthur - aka Golda's Mom. Teresa was diagnosed in 2018 and has been living with recurring ovarian cancer for the last seven years, spending almost half of every year in chemotherapy treatment. She talks candidly with Golda about her health challenges and quality of life in survivorship. Take a listen to Teresa's story with ovarian cancer, which we told in our very first season here: https://overlooked.simplecast.com/episodes/fluid-puppySubscribe to the newsletter for more background on this episode: https://overlookedpodcast.kit.com/e4b85028b6If you're in New York City, come to our first listener ‘Meet & Greet' at 787 Coffee in Manhattan on May 31st. Tickets are free but limited - register here.  https://www.eventbrite.ca/e/overlooked-podcast-meet-greet-tickets-1352683656229?aff=oddtdtcreator LIKE WHAT YOU HEAR? Support the show by:- Leaving a review on Apple, Spotify, or wherever you're listening.- Becoming a Patron - Overlooked is on Patreon, where you can and get rewards like merch, the ability to send in questions for expert guests, and a 'backstage pass' to the show. New to Overlooked? Welcome. Overlooked was launched in 2023 to tell the story of ovarian cancer through one woman's story. In 2024 the show started to cover other overlooked topics in women's health - and there are many. The show is hosted by Golda Arthur, an audio journalist and producer. EMAIL US: hello@overlookedpod.com FOLLOW US:Instagram https://www.instagram.com/overlookedpod/LinkedIn https://www.linkedin.com/company/105541285/admin/dashboard/ LEARN MORE: https://overlookedpod.com/ DISCLAIMER What you hear and read on ‘Overlooked' is for general information purposes only and represents the opinions of the host and guests. The content on the podcast and website should not be taken as medical advice. Every person's body is unique, so please consult your healthcare professional for any medical questions that may arise.

Research To Practice | Oncology Videos
For Oncology Nurses: Ovarian Cancer — Proceedings from the 2025 Annual ONS Congress

Research To Practice | Oncology Videos

Play Episode Listen Later May 1, 2025 91:27


Featuring perspectives from Ms Courtney Arn, Ms Jennifer Filipi, Dr David M O'Malley and Dr Shannon N Westin, including the following topics: Introduction: Overview of Ovarian Cancer (OC) Management (0:00) Genetic Testing for Newly Diagnosed Advanced OC (14:31) Role of PARP Inhibitor Maintenance in Newly Diagnosed Advanced OC (22:46) Other Available and Investigational Novel Strategies for OC (43:56) Current and Future Role of Mirvetuximab Soravtansine in OC Treatment (1:19:24) NCPD information and select publications

Chrissie, Sam & Browny
Brissie Pool Bandit Reveals Bizarre Reason Behind Dips

Chrissie, Sam & Browny

Play Episode Listen Later May 1, 2025 36:21 Transcription Available


Plus! Chrissie's back with more sweeping statements and Julia Busuttil joins us for a chat about Witchery's Ovarian Cancer campaign.See omnystudio.com/listener for privacy information.

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Oncology & Hematology CME/CNE/CPE Video Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Oncology & Hematology CME/CNE/CPE Video Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Internal Medicine CME/CNE/CPE Video Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Internal Medicine CME/CNE/CPE Video Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Internal Medicine CME/CNE/CPE Audio Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Internal Medicine CME/CNE/CPE Audio Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Oncology & Hematology CME/CNE/CPE Audio Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Oncology & Hematology CME/CNE/CPE Audio Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast
Kathleen N. Moore, MD, MS - A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast

Play Episode Listen Later Apr 24, 2025 64:16


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UYH865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Foundation for Women's Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Merck & Co., Inc., Rahway, NJ, USA, and Sutro Biopharma, Inc.Disclosure information is available at the beginning of the video presentation.

Cannabis Health Radio Podcast
Episode 446: No Evidence of Disease: Beating Ovarian Cancer With Cannabis Oil

Cannabis Health Radio Podcast

Play Episode Listen Later Apr 23, 2025 35:52


In this episode, our guest Sharon, from Scotland, shares her powerful journey of overcoming stage 3 ovarian cancer. After a difficult experience with chemotherapy, Sharon turned to cannabis oil—and believes it played a key role in her survival. Now cancer-free and devoted to helping others, she opens up about the stigma, the scams, the healing, and the deeper personal transformation that followed.This is a story of fierce determination, intuitive self-advocacy, and the healing potential of plant medicine.00:38 – Introduction: Ovarian cancer stats and global impact01:52 – Sharon's first symptoms and long path to diagnosis03:02 – The moment she was told she had cancer04:46 – Mental health, grief, and personal transformation06:56 – Relationships lost and reshaped after diagnosis07:10 – Chemotherapy: side effects and regret08:39 – Finding cannabis oil and getting scammed10:29 – The importance of trusted sources and education11:12 – Taking oil before, during, and after chemo13:40 – “I'd be dead without it”—how cannabis helped her survive17:39 – Continued use of oil and current regimen19:31 – Managing chemo-induced neuropathy21:40 – Family dynamics and their view of cannabis23:12 – Survivor's guilt and a desire to help others28:01 – Nutrition, self-care, and guiding others toward options30:57 – Her advice to women newly diagnosed with ovarian cancer34:39 – Final thoughts and gratitude Visit our website: CannabisHealthRadio.comDiscover products and get expert advice from Swan ApothecaryFollow us on Facebook.Follow us on Instagram.Find us on Rumble.Keep your privacy! Buy NixT420 Odor Remover

PeerVoice Oncology & Haematology Video
Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

PeerVoice Oncology & Haematology Video

Play Episode Listen Later Apr 21, 2025 61:37


Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

PeerVoice Oncology & Haematology Audio
Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

PeerVoice Oncology & Haematology Audio

Play Episode Listen Later Apr 21, 2025 61:37


Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

PeerVoice Internal Medicine Audio
Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

PeerVoice Internal Medicine Audio

Play Episode Listen Later Apr 21, 2025 61:37


Diana N. Ionescu, MD - To Target We Need to Test: Why and How to Identify Folate Receptor Alpha-Positive Ovarian Cancer

Research To Practice | Oncology Videos
Ovarian Cancer — Proceedings from a Session Held During the 2025 SGO Annual Meeting on Women's Cancer®

Research To Practice | Oncology Videos

Play Episode Listen Later Apr 17, 2025 89:33


Featuring perspectives from Dr Kathleen N Moore, Dr Ritu Salani, Dr Angeles Alvarez Secord and Dr Shannon N Westin, moderated by Dr Secord, including the following topics: Introduction (0:00) Up-Front Treatment for Advanced Ovarian Cancer (OC) — Dr Westin (2:42) Management of Relapsed/Refractory OC — Dr Secord (23:06) Novel Investigational Therapies for Advanced OC — Dr Moore (46:55) Diagnosis and Management of Adverse Events Associated with Commonly Employed Therapies for Advanced OC — Dr Salani (1:08:34) CME information and select publications

Gynecologic Oncology Update
Ovarian Cancer — Proceedings from a Session Held During the 2025 Society of Gynecologic Oncology Annual Meeting on Women's Cancer®️

Gynecologic Oncology Update

Play Episode Listen Later Apr 17, 2025 89:33


Dr Kathleen Moore, Dr Ritu Salani, Dr Shannon Westin and moderator Dr Angeles Alvarez Secord share their perspectives and summarize recently presented data from the SGO 2025 annual meeting guiding the management of ovarian cancer. CME information and select publications here.

Westchester Talk Radio
Episode 173: Non-Profit Spotlight Support Connection - Hosted by Andrew Castellano featuring Violeta

Westchester Talk Radio

Play Episode Listen Later Apr 9, 2025 5:14


Each year, thousands of people come together to participate in the Support Connection's Annual Support-A-Walk for Breast & Ovarian Cancer, an uplifting community event dedicated to raising awareness and providing support for those living with breast, ovarian, or any gynecological cancer. Family members, friends, and supporters unite to celebrate, encourage, and remember their loved ones affected by these cancers. It's a powerful reminder that no one should face cancer alone, and the event serves as an opportunity for individuals, businesses, and organizations to express their compassion and support for those going through their cancer journeys. On October 6, 2024, Westchester Talk Radio's Andrew Castellano had the opportunity to speak with Violeta, a participant at the event.

Westchester Talk Radio
Episode 173: Non-Profit Spotlight Support Connection - Hosted by Andrew Castellano featuring Stacey Thompson

Westchester Talk Radio

Play Episode Listen Later Apr 9, 2025 5:49


The Support Connection's Annual Support-A-Walk for Breast & Ovarian Cancer held on October 6, 2024, was a powerful and inspiring community event that brought together thousands of participants united by a shared mission: to support individuals living with breast, ovarian, or any gynecological cancer. Held each year, the Support-A-Walk raises essential funds to provide free support services such as one-on-one peer counseling, support groups, educational and wellness programs, and social activities. These services have made a profound difference in the lives of those facing cancer, offering them hope, strength, and a sense of community. The event is not only about raising funds—it's about creating a space where people can feel supported and connected. Families and friends walked together, celebrating survivors, supporting those currently battling cancer, and remembering those who have been lost. The walk serves as a reminder that no one has to face cancer alone. Businesses, organizations, and individuals from the community came together, showing their encouragement and compassion through participation, sponsorship, and donations. During the event, Westchester Talk Radio's Andrew Castellano had the opportunity to speak with Stacey Thompson about the meaningful impact of Support Connection's work.

True Healing with Robert Morse ND
Dr. Morse Q&A - Transverse Myelitis - Muscle Development - Energy Levels - Stage 3C Ovarian Cancer #762

True Healing with Robert Morse ND

Play Episode Listen Later Apr 5, 2025 64:59


To have your question featured in a future video, please email: questions@morses.tv Please include at least: Age, Weight and as much history as possible.

Cannabis Health Radio Podcast
Episode 443: She Was Given Only Months To Live With Stage 4 Ovarian Cancer—11 Years Ago

Cannabis Health Radio Podcast

Play Episode Listen Later Apr 2, 2025 40:29


In 2014, at the age of 51, Diane was diagnosed with stage 4 ovarian cancer with a BRCA mutation. Doctors told her she had just months to live. In this episode, Diane Doyle shares how she took control of her own healing, the challenges she faced in navigating both conventional and alternative treatments, and why she believes cannabis was the key to her survival. Her story is a testament to the power of perseverance, self-education, and never giving up hope.01:13 – Diane's initial diagnosis and how it was discovered04:35 – Reaction to being told she had only months to live06:58 – How Diane approached her healing journey from the beginning10:42 – Why she chose to combine conventional and alternative treatments14:25 – Discovering cannabis and how she began using it18:09 – The reaction from her doctors20:55 – What Diane believes made the biggest difference in her outcome24:36 – Side effects, setbacks, and how she adjusted29:45 – The emotional and spiritual aspects of healing33:10 – Where she is today, 11 years later36:22 – Advice for others facing a similar diagnosis39:00 – Final thoughts and gratitude Visit our website: CannabisHealthRadio.comFollow us on Facebook.Follow us on Instagram.Find us on Rumble.Keep your privacy! Buy NixT420 Odor Remover

WWL First News with Tommy Tucker
A New Orleans biotech company is working on a test to detect ovarian cancer earlier

WWL First News with Tommy Tucker

Play Episode Listen Later Mar 21, 2025 8:25


A biotech start-up in New Orleans is working on a liquid biopsy test that could detect ovarian cancer much earlier and save lives. Tommy talks with Christopher Millan, Founder & CEO of Beken Bio

Public Health On Call
871 - A Potentially “Game-Changing” Approach to Preventing Ovarian Cancer

Public Health On Call

Play Episode Listen Later Mar 19, 2025 19:28


About this episode: For some people with a high risk of ovarian cancer, a standard approach has been full removal of the reproductive organs. But new research points to a far less invasive procedure called a salpingectomy, or removal of the fallopian tubes, as a potential “game changer” in ovarian cancer. In this episode: understanding high grade serous carcinoma—the most common type of ovarian cancer—the lack of screening tools, and why fallopian tube removal isn't yet available to more people. Guest: Dr. Rebecca Stone is an OBGYN, a professor in the Johns Hopkins Medicine Department of Gynecology and Obstetrics, and the director of The Kelly Gynecologic Oncology Service. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs, the largest center at the Johns Hopkins Bloomberg School of Public Health. Show links and related content: A Game-Changer for Ovarian Cancer—Johns Hopkins Medicine Salpingectomy for ectopic pregnancy reduces ovarian cancer risk—JNCI Cancer Spectrum Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review—NIH Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed

ASCO Daily News
The Evolving Role of Precision Surgery in Gynecologic Cancers

ASCO Daily News

Play Episode Listen Later Mar 13, 2025 25:50


Dr. Ebony Hoskins and Dr. Andreas Obermair discuss the surgical management of gynecologic cancers, including the role of minimally invasive surgery, approaches in fertility preservation, and the nuances of surgical debulking. TRANSCRIPT Dr. Ebony Hoskins: Hello and welcome to the ASCO Daily News Podcast, I'm Dr. Ebony Hoskins. I'm a gynecologic oncologist at MedStar Washington Hospital Center in Washington, DC, and your guest host of the ASCO Daily News Podcast. Today we'll be discussing the surgical management of gynecologic cancer, including the role of minimally invasive surgery (MIS), approaches in fertility preservation, and the nuances of surgical debulking, timing, and its impact on outcomes. I am delighted to welcome Dr. Andreas Obermair for today's discussion. Dr. Obermair is an internationally renowned gynecologic oncologist, a professor of gynecologic oncology at the University of Queensland, and the head of the Queensland Center for Gynecologic Cancer Research. Our full disclosures are available in the transcript of this episode. Dr. Obermair, it's great speaking with you today. Dr. Andreas Obermair: Thank you so much for inviting me to this podcast. Dr. Ebony Hoskins: I am very excited.  I looked at your paper and I thought, gosh, is everything surgical? This is everything that I deal with daily in terms of cancer in counseling patients. What prompted this review regarding GYN cancer management? Dr. Andreas Obermair: Yes, our article was published in the ASCO Educational Book; it is volume 44 in 2024. And this article covers some key aspects of targeted precision surgical management principles in endometrial cancer, cervical cancer, and ovarian cancer. While surgery is considered the cornerstone of gynecologic cancer treatment, sometimes research doesn't necessarily reflect that. And so I think ASCO asked us to; so it was not just me, there was a team of colleagues from different parts of the United States and Australia to reflect on surgical aspects of gynecologic cancer care and I feel super passionate about that because I do believe that surgery has a lot to offer. Surgical interventions need to be defined and overall, I see the research that I'm doing as part of my daily job to go towards precision surgery. And I think that is, well, that is something that I'm increasingly passionate for. Dr. Ebony Hoskins: Well, I think we should get into it. One thing that comes to mind is the innovation of minimally invasive surgery in endometrial cancer. I always reflect on when I started my fellowship, I guess it's been about 15 years ago, all of our endometrial cancer patients had a midline vertical incision, increased risk of abscess, infections and a long hospital stay. Do you mind commenting on how you see management of endometrial cancer today? Dr. Andreas Obermair: Thank you very much for giving the historical perspective because the generation of gynecologic oncologists today, they may not even know what we dealt with, what problems we had to solve. So like you, when I was a fellow in gynecologic oncology, we did midline or lower crosswise incisions, the length of stay was, five days, seven days, but we had patients in hospital because of complications for 28 days. We took them back to the operating theaters because those are patients with a BMI of 40 plus, 45, 50 and so forth. So we really needed to solve problems. And then I was exposed to a mentor who taught minimal invasive surgery. And in Australia he was one of the first ones who embarked on that. And I can remember, I was mesmerized by this operation, like not only how logical this procedure was, but also we did rounds afterwards. And I saw these women after surgery and I saw them sitting upright, lipstick on, having had a full meal at the end of the day. And I thought, wow, this is the most rewarding experience that I have to round these patients after surgery. And so I was thinking, how could I help to establish this operation as standard? Like a standard that other people would accept this is better. And so I thought we needed to do a trial on this. And then it took a long time. It took a long time to get the support for the [LACE - Laparoscopic Approach to Cancer of the Endometrium] trial. And in this context, I just also wanted to remind us all that there were concerns about minimal invasive surgery in endometrial cancer at the time. So for example, one of the concerns was when I submitted my grant funding applications, people said, “Well, even if we fund you, wouldn't be able to do this trial because there are actually no surgeons who actually do minimally invasive surgery.” And at the time, for example, in Australia, there were maybe five people, a handful of people who were able to do this operation, right? This was about 20 years ago. The other concern people had was they were saying, could minimally invasive surgery for endometrial cancer, could that cause port side metastasis because there were case reports. So there were a lot of things that we didn't know anyway. We did this trial and I'm super happy we did this trial. We started in 2005, and it took five years to enroll. At the same time, GOG LAP2 was ramping up and the LACE trial and GOG LAP2 then got published and provided the foundations for minimally invasive surgery in endometrial cancer. I'm super happy that we have randomized data about that because now when we go back and now when people have concerns about this, should we do minimally invasive surgery in P53 mutant tumors, I'm saying, well, we actually have data on that. We could go back, we could actually do more research on that if we wanted to, but our treatment recommendations are standing on solid feet. Dr. Ebony Hoskins: Well, my patients are thankful. I see patients all the time and they have high risk and morbidly obese, lots of medical issues and actually I send them home most the same day. And I think, you know, I'm very appreciative of that research, because we obviously practice evidence-based and it's certainly a game changer. Let's go along the lines of MIS and cervical cancer. And this is going back to the LACC [Laparoscopic Approach to Cervical Cancer] trial.  I remember, again, one of these early adopters of use of robotic surgery and laparoscopic surgery for radical hysterectomy and thought it was so cool. You know, we can see all the anatomy well and then have the data to show that we actually had a decreased survival. And I even see that most recent updated data just showing it still continued. Can you talk a little bit about why you think there is a difference? I know there's ongoing trials, but still interested in kind of why do you think there's a survival difference? Dr. Andreas Obermair:  So Ebony, I hope you don't mind me going back a step. So the LACC study was developed from the LACE trial. So we thought we wanted to reproduce the LACE data/LAP2 data. We wanted to reproduce that in cervix cancer. And people were saying, why do you do that? Like, why would that be different in any way? We recognize that minimally invasive radical hysterectomy is not a standard. We're not going to enroll patients in a randomized trial where we open and do a laparotomy on half the patients. So I think the lesson that really needs to be learned here is that any surgical intervention that we do, we should put on good evidence footing because otherwise we're really running the risk of jeopardizing patients' outcomes. So, that was number one and LACC started two years after LACE started. So LACC started in 2007, and I just wanted to acknowledge the LACC principal investigator, Dr. Pedro Ramirez, who at the time worked at MD Anderson. And we incidentally realized that we had a common interest. The findings came totally unexpected and came as an utter shock to both of us. We did not expect this. We expected to see very similar disease-free and overall survival data as we saw in the endometrial cancer cohort. Now LACC was not designed to check why there was a difference in disease-free survival. So this is very important to understand. We did not expect it. Like, so there was no point checking why that is the case. My personal idea, and I think it is fair enough if we share personal ideas, and this is not even a hypothesis I want to say, this is just a personal idea is that in endometrial cancer, we're dealing with a tumor where most of the time the cancer is surrounded by a myometrial shell. And most of the time the cancer would not get into outside contact with the peritoneal cavity. Whereas in cervix cancer, this is very different because in cervix cancer, we need to manipulate the cervix and the tumor is right at the outside there. So I personally don't use a uterine manipulator. I believe in the United States, uterine manipulators are used all the time. My experience is not in this area, so I can't comment on that. But I would think that the manipulation of the cervix and the contact of the cervix to the free peritoneal cavity could be one of the reasons. But again, this is simply a personal opinion. Dr. Ebony Hoskins: Well, I appreciate it. Dr. Andreas Obermair: Ebony at the end of the day, right, medicine is empirical science, and empirical science means that we just make observations, we make observations, we measure them, and we pass them on. And we made an observation. And, and while we're saying that, and yes, you're absolutely right, the final [LACC] reports were published in JCO recently. And I'm very grateful to the JCO editorial team that they accepted the paper, and they communicated the results because this is obviously very important. At the same time, I would like to say that there are now three or four RCTs that challenge the LACC data. These RCTs are ongoing, and a lot of people will be looking forward to having these results available. Dr. Ebony Hoskins: Very good. In early-stage cervical cancer, the SHAPE trial looked at simple versus radical hysterectomy in low-risk cervical cancer patients. And as well all know, simple hysterectomy was not inferior to radical hysterectomy with respect to the pelvic recurrence rate and any complications related to surgery such as urinary incontinence and retention. My question for you is have you changed your practice in early-stage cervical cancer, say a patient with stage 1B1 adenocarcinoma with a positive margin on conization, would you still offer this patient a radical hysterectomy or would you consider a simple hysterectomy? Dr. Andreas Obermair:  I think this is a very important topic, right? Because I think the challenge of SHAPE is to understand the inclusion criteria. That's the main challenge. And most people simplify it to 2 cm, which is one of the inclusion criteria but there are two others and that includes the depth of invasion. Dr. Marie Plante has been very clear. Marie Plante is the first author of the SHAPE trial that's been published in the New England Journal of Medicine only recently and Marie has been very clear upfront that we need to consider all three inclusion criteria and only then the inclusion criteria of SHAPE apply. So at the end of the day, I think what the SHAPE trial is telling us that small tumors that would strictly fulfill the criteria of a 1B or 1B1 cancer of the cervix can be considered for a standard type 1 or PIVA type 1 or whatever classification we're trying to use will be eligible. And that makes a lot of sense. I personally not only look at the size, I also look at the location of the tumor. I would be very keen that I avoid going through tumor tissue because for example, if you have a tumor that is, you know, located very much in one corner of the cervix and then you do a standard hysterectomy and then you have a positive tumor margin that would be obviously, most people would agree it would be an unwanted outcome. So I'd be very keen checking the location, the size of the tumor, the depths of invasion and maybe then if the tumor for example is on one side of the cervix you can do a standard approach on the contralateral side but maybe do a little bit more of a margin, a parametrial margin on the other side. Or if a tumor is maybe on the posterior cervical lip, then you don't need to worry so much about the anterior cervical margin, maybe take the rectum down and maybe try to get a little bit of a vaginal margin and the margin on the uterus saccals. Just really to make sure that you do have margins because typically if we get it right, survival outcomes of clinical stage 1 early cervix cancer 1B1 1B 2 are actually really good. It is a very important thing that we get the treatment right. In my practice, I use a software to record my treatment outcomes and my margins. And I would encourage all colleagues to be cognizant and to be responsible and accountable to introduce accountable clinical practice, to check on the margins and check on the number on the percentage of patients who require postoperative radiation treatment or chemo radiation. Dr. Ebony Hoskins: Very good. I have so many questions for you. I don't know the statistics in Australia, but here, there's increased rising of endometrial cancer and certainly we're seeing it in younger women. And fertility always comes up in terms of kind of what to do. And I look at the guidelines and, see if I can help some of the women if they have early-stage endometrial cancer. Your thoughts on what your practice is on use of someone who may meet criteria, if you will. The criteria I use is grade 1 endometrioid adenocarcinoma. No myometria invasion. I try to get MRI'd and make sure that there's no disease outside the endometrium. And then if they make criteria, I typically would do an IUD. Can you tell me what your practice is and where you've had success? Dr. Andreas Obermair: So, we initiated the feMMe clinical trial that was published in 2021 and it was presented in a Plenary at one of the SGO meetings. I think it was in 2021, and we've shown complete pathological response rates after levonorgestrel intrauterine device treatment. And so in brief, we enrolled patients with endometrial hyperplasia with atypia, but also patients with grade 1 endometrial adenocarcinoma. Patients with endometrial hyperplasia with atypia had, in our series, had an 85 % chance of developing a complete pathological response. And that was defined as the complete absence of any atypia or cancer. So endometrial hyperplasia with atypia responded in about 85%. In endometrial cancer, it was about half, it was about 45, 50%. In my clinical practice, like as you, I see patients, you know, five days a week. So I'm looking after many patients who are now five years down from conservative treatment of endometrial cancer. There are a lot of young women who want to get pregnant, and we had babies, and we celebrate the babies obviously because as gynecologist obstetricians it couldn't get better than that, right, if our cancer patients have babies afterwards. But we're also treating women who are really unfit for surgery and who are frail and where a laparoscopic hysterectomy would be unsafe. So this phase is concluded, and I think that was very successful. At least we're looking to validate our data. So we're having collaborations, we're having collaborations in the United States and outside the United States to validate these data. And the next phase is obviously to identify predictive factors, to identify predictors of response. Because as you can imagine, there is no point treating patients with a levonorgestrel intrauterine joint device where we know in advance that she's not going to respond. So this is a very, very fascinating story and we got our first set of data already, but now we just really need to validate this data. And then once the validation is done, my unit is keen to do a prospective validation trial. And that also needs to involve international collaborators. Dr. Ebony Hoskins: Very good. Moving on to ovarian cancer, we see patients with ovarian cancer with, say, at least stage 3C or higher who started neoadjuvant chemotherapy. Now, some of these patients are hearing different things from their medical oncologist versus their gynecologic oncologist regarding the number of cycles of neoadjuvant chemotherapy after getting diagnosed with ovarian cancer. I know that this can be confusing for our patients coming from a medical oncologist versus a gynecologic oncologist. What do you say to a patient who is asking about the ideal number of chemotherapy cycles prior to surgery? Dr. Andreas Obermair: So this is obviously a very, very important topic to talk about. We won't be able to provide a simple off the shelf answer for that, but I think data are emerging.  The ASCO guidelines should also be worthwhile considering because there are actually new ASCO Guidelines [on neoadjuvant chemotherapy for newly diagnosed, advanced ovarian cancer] that just came out a few weeks ago and they would suggest that we should be aiming for R0 in surgery. If we can maybe take that as the pivot point and then go back and say, okay, so what do need to do to get the patient to zero?  I'm not an ovarian cancer researcher; I'm obviously a practicing gynecologic oncologist. I think about things a lot and things like that. In my practice, I would want a patient to develop a response after neoadjuvant chemotherapy. So, if a patient doesn't have a response after two or three cycles, then I don't see the point for me to offer her an operation. In my circle with the medical oncologists that I work with, I have a very, very good understanding. So, they send the patient to me, I take them to the theater. I take a good chunk of tissue from the peritoneum. We have a histopathologic diagnosis, we have a genomic diagnosis, they go home the same day. So obviously there is no hospital stay involved with that. They can start the chemotherapy after a few days. There is no hold up because the chances of surgical complication in a setting like this is very, very low. So I use laparoscopy to determine whether the patient responds or not. And for many of my patients, it seems to work. It's obviously a bit of an effort and it takes operating time. But I think I'm increasing my chances to make the right decision. So, coming back to your question about whether we should give three or six cycles, I think the current recommendations are three cycles pending the patient's response to neoadjuvant chemotherapy because my aim is to get a patient to R0 or at least minimal residual disease. Surgery is really, in this case, I think surgery is the adjunct to systemic treatment. Dr. Ebony Hoskins: Definitely. I think you make a great point, and I think the guideline just came out, like you mentioned, regarding neoadjuvant. And I think the biggest thing that we need to come across is the involvement of a gynecologic oncologist in patients with ovarian cancer. And we know that that survival increases with that involvement. And I think the involvement is the surgery, right? So, maybe we've gotten away from the primary tumor debulking and now using more neoadjuvant, but surgery is still needed. And so, I definitely want to have a take home that GYN oncology is involved in the care of these patients upfront. Dr. Andreas Obermair: I totally support that. This is a very important statement. So when I'm saying surgery is the adjunct to medical treatment, I don't mean that surgery is not important. Surgery is very important. And the timing is important. And that means that the surgeons and the med oncs need to be pulling on the same string. The med oncs just want to get the cytotoxic into the patients, but that's not the point, right? We want to get the cytotoxic into the patients at the right time because if we are working under this precision surgery, precision treatment mantra, it's not only important what we do, but also doing it at the right time. And ideally, I I would like to give surgery after three cycles of neoadjuvant chemotherapy, if that makes sense. But sometimes for me as a surgeon, I talk to my med onc colleagues and I say, “Look, she doesn't have a good enough response to her treatment and I want her to receive six cycles and then we re-evaluate or change medical treatment,” because that's an alternative that we can swap out drugs and treat upfront with a different drug and then sometimes they do respond. Dr. Ebony Hoskins:  I have maybe one more topic. In the area I'm in, in the Washington D.C. area, we see lots of endometrial cancer and they're not grade 1, right? They're high-risk endometrial cancer and advanced. So a number of patients with stage 3 disease, some just kind of based off staging and then some who come in with disease based off of the CT scan, sometimes omental caking, ascites. And the real question is we have extrapolated the use of neoadjuvant chemotherapy to endometrial cancer. It's similar, but not the same. So my question is in an advanced endometrial cancer, do you think there's still a role, when I say advanced, I mean, maybe stage 4, a role for surgery? Dr. Andreas Obermair: Most definitely. But the question is when do you want to give this surgery? Similar to ovarian cancer, in my experience, I want to get to R0. What am I trying to achieve here? So, I reckon we should do a trial on this. And I reckon we have, as you say, the number of patients in this setting is increasing, we could do a trial. I think if we collaborate, we would have enough patients to do a proper trial. Obviously, we would start maybe with a feasibility trial and things like that. But I reckon a trial would be needed in this setting because I find that the incidence that you described, that other people would come across, they're becoming more and more common. I totally agree with you, and we have very little data on that. Dr. Ebony Hoskins: Very little and we're doing what we can. Dr. Obermair, thank you for sharing your fantastic insights with us today on the ASCO Daily News Podcast and for all the work you do to advance care for patients with gynecologic cancer. Dr. Andreas Obermair: Thank you, Dr. Hoskins, for hosting this and it's been an absolute pleasure speaking with you today. Dr. Ebony Hoskins: Definitely a pleasure and thank you to our listeners for your time today. Again, Dr. Obermair's article is titled, “Controversies in the Surgical Management of Gynecologic Cancer: Balancing the Decision to Operate or Hesitate,” and was published in the 2024 ASCO Educational Book. And you'll find a link to the article in the transcript of this episode. Finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Ebony Hoskins @drebonyhoskins Dr. Andreas Obermair @andreasobermair Follow ASCO on social media:       @ASCO on Twitter       ASCO on Bluesky   ASCO on Facebook       ASCO on LinkedIn       Disclosures:   Dr. Ebony Hoskins: No relationships to disclose. Dr. Andreas Obermair: Leadership: SurgicalPerformance Pty Ltd. Stock and Ownership Interests: SurgicalPerformance Pty Ltd. Honoraria: Baxter Healthcare Consulting or Advisory Role: Stryker/Novadaq Patents, Royalties, and Other Intellectual Property: Shares in SurgicalPerformance Pty Ltd. Travel, Accommodation, Expenses: Stryker    

Radical Remission Project ”Stories That Heal” Podcast
Sharon Dobbs-Richards: Metastatic Ovarian Cancer Thriver

Radical Remission Project ”Stories That Heal” Podcast

Play Episode Listen Later Mar 12, 2025 50:22


In 2017 Sharon was diagnosed with ovarian cancer. She underwent a radical surgery and chemotherapy. She had a recurrence in late 2019 and after more chemotherapy was told she had widespread bone metastacies. At that point, Sharon stopped all conventional treatment and opted for mistletoe and a functional medicine approach. She has been NED since late 2020 and continues with functional medicine and mistletoe. Today Sharon lives in London, is a clinical nurse and a trained functional medicine practitioner. She is passionate about raising awareness around ovarian cancer and functional medicine.  To learn more about Sharon and her healing journey visit - sharondobbs-richards.com or email her directly at sharon@sharondobbs-richards.com. You can purchase Sharon's novel called, How To Kill Your Gynecologist, on Amazon Follow Sharon on LinkedIn  To find your Functional Medicine practitioner visit www.ifm.org Learn more about Sharon's breathwork practitioner at sophietrew.com ________________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here.  To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook  Instagram YouTube ______________ Thank you to our friends from The Healing Oasis for sponsoring this episode of the podcast.  The Healing Oasis is a first of its kind in beautiful British Columbia, Canada where we encourage the body to heal from cancer using alternative therapies & cancer fighting meals at a wellness retreat center in nature. Our top naturopathic cancer doctor will prescribe a protocol tailored specifically for you. There's no place quite like it. Start your healing journey today! Learn More about The Healing Oasis by visiting these links: Website   Testimonials Video Overview  

SolFul Connections
Taylor Made: A Life of Strength, Grace, and Resilience

SolFul Connections

Play Episode Listen Later Mar 4, 2025 43:14


This special Encore Episode of the SolFul Connections podcast features Taylor O' Brien, who shares how her diagnosis farian Cancer in her twenties has shaped her perspective on healthcare, wellness, and life.Armed with knowledge and a mission, Taylor reveals some important insights and advice that could help all of us navigate our own wellness journey. The conversation with this young, beautiful, and brave woman is inspiring and thought-provoking. Friendship, advocacy, and who we are at our core are all topics addressed in this special discussion.For more on Cancer - and the low-grade Ovarian Cancer with which Taylor was diagnosed, visit www.cancer.orgHelp me to honor and applaud Taylor, who continues to spread her message and her powerful light.

Morning Medical Update
Morning Medical Update - Ovarian Cancer

Morning Medical Update

Play Episode Listen Later Mar 3, 2025 30:45


She spotted her own ovarian cancer. Now she's keeping it in check. Hear one woman's story regarding her diagnosis and survivorship.

PRS Journal Club
Episode 1, A Precision Medicine Approach for Advanced Ovarian Cancer

PRS Journal Club

Play Episode Listen Later Feb 26, 2025 16:40


In the first episode of A Deep Dive into HRD Testing in Ovarian Cancer, a three-part podcast series sponsored by AstraZeneca, we're speaking with Dr. Kathleen Moore about HRD testing in ovarian cancer and its clinical significance in helping aid precision medicine approaches.   Dr. Kathleen Moore is a Professor of Gynecologic Oncology at the University of Oklahoma Health Sciences Center, Associate Director of Clinical Research and Director of the Oklahoma TSET Phase I Program at the Stephenson Cancer Center. A graduate of the University of Washington School of Medicine, WA, Dr. Moore completed her residency in gynecology at the University Health Center of Pittsburgh in Pittsburgh, PA and completed a fellowship in gynecologic oncology at the University of Oklahoma College of Medicine in Oklahoma City, OK. She is board certified in obstetrics and gynecology as well as gynecologic oncology and hospice and palliative care.   For more information, visit: https://www.azprecisionmed.com/tumor-type/ovarian-cancer/hrd-testing.html For patient resources, please visit TestForHRD.com.   This podcast does not necessarily reflect the opinions of AstraZeneca and are the spokeperson's opinions and experience.

PRS Journal Club
Episode 2, HRD Testing Deep-Dive

PRS Journal Club

Play Episode Listen Later Feb 26, 2025 7:23


In the second episode of A Deep Dive into HRD Testing in Ovarian Cancer, a three-part podcast series sponsored by AstraZeneca, we're speaking with Dr. Erin Crane who will highlight how HRD testing provides helpful information to ovarian cancer patients.   Erin K. Crane, MD, MPH, is a gynecologic oncologist with Atrium Health Levine Cancer in Charlotte, North Carolina. A graduate of the SUNY Upstate Medical University in Syracuse, NY, Dr. Crane completed her residency at the University of Virginia and a fellowship at The University of Texas MD Anderson Cancer Center in Gynecologic Oncology. She is board certified by the American Board of Obstetrics and Gynecology in Gynecologic Oncology and Obstetrics and Gynecology. Dr. Crane is a Clinical Associate Professor of Obstetrics and Gynecology at the Wake Forest University School of Medicine.   For more information, visit https://www.azprecisionmed.com/tumor-type/ovarian-cancer/hrd-testing.html For patient resources, please visit TestForHRD.com.   This podcast does not necessarily reflect the opinions of AstraZeneca and are the spokesperson's opinions and experience.

PRS Journal Club
Episode 3, Better Informed Patient Journeys

PRS Journal Club

Play Episode Listen Later Feb 26, 2025 11:17


In the third episode of A Deep Dive Into HRD Testing in Ovarian Cancer, a three-part podcast series sponsored by AstraZeneca, we're speaking with Dr. David O'Malley, and Bobbie R, an ovarian cancer patient. Dr. O'Malley will highlight how HRD testing empowers ovarian cancer patients to make more informed decisions with their doctors to help guide their treatment journey, and Bobbie will provide insight into her experience with HRD testing.   Dr. David O'Malley is a professor in the department of Obstetrics and Gynecology at The Ohio State University College of Medicine and the director of the Division of Gynecologic Oncology at the OSUCCC – James.   Bobbie is a stage 3C ovarian cancer patient who lives in Rochester, New York. Bobbie is an animal rights activist, vegetarian, and exerciser who recently retired from the healthcare field, having worked as a registered nurse and owner of a healthcare staffing firm. Following her diagnosis in July of 2021, Bobbie participated in biomarker testing which indicated that she was breast cancer gene (BRCA) negative and homologous recombination deficiency (HRD) positive. After undergoing surgery and chemotherapy as first-line treatment, Bobbie's oncologist explained that she was eligible for a poly-ADP ribose polymerase (PARP) inhibitor due to her HRD status and on March 7, 2022, Bobbie started on a PARP inhibitor for maintenance treatment. As she continues treatment in 2024, Bobbie celebrates over 45 years of marriage with her husband and looks forward to traveling the United States, reading good books, and spending time with her dogs.   For more information, visit https://www.azprecisionmed.com/tumor-type/ovarian-cancer/hrd-testing.html   For patient resources, please visit TestForHRD.com.   This podcast does not necessarily reflect the opinions of AstraZeneca and are the spokespeople's opinions and experiences.

SBS Russian - SBS на русском языке
Dr Olga Kondrashova: "One of the challenges of ovarian cancer is that its symptoms are unclear" - Доктор Ольга Кондрашова: "Одна из проблем рака яичников - это нечеткие симптомы"

SBS Russian - SBS на русском языке

Play Episode Listen Later Feb 25, 2025 10:26


February is ovarian cancer awareness month. Dr Olga Kondrashova leads the Molecular Oncology team at the Queensland Institute for Medical Research, QIMR Berghofer. She told SBS Russian about the changes in the ovarian cancer treatments, and about her journey in science. - Февраль - это месяц повышения осведомленности о раке яичников. Доктор Ольга Кондрашова возглавляет группу молекулярной онкологии в Институте медицинских исследований Квинсленда, QIMR Berghofer. Она рассказала о том, как изменился подход к лечению рака яичников, почему его сложно диагностировать, а также о своем пути в науку.

Fertility Forward
Ep 160: A Journey of IVF, Ovarian Cancer, Surrogacy, and Motherhood with Jess Jata

Fertility Forward

Play Episode Listen Later Feb 20, 2025 33:52 Transcription Available


Every single fertility journey is unique and often, things don't go as planned. Today on Fertility Forward, we are joined by ovarian cancer survivor and mom of twins, Jess Jata to hear all about her unexpected journey and how infertility actually saved her life. Tuning in, you'll hear all about how Jessica's IVF experience led her to being diagnosed with ovarian cancer and having an emergency hysterectomy. We delve into how she managed to start a family through surrogacy, what gave her strength during such a challenging time, what Jess shares on her Instagram community, and so much more! Finally, our guest discusses the path to getting stronger in the face of hardship and as always, shares what she's grateful for today. To hear all of this and so much more from such an inspirational and resilient woman, press play now!  

Intelligent Medicine
Intelligent Medicine Radio for February 8, Part 1: A Natural Antidote to Hair Graying

Intelligent Medicine

Play Episode Listen Later Feb 10, 2025 42:25


Neuroprotection is just about pricey moonshot Alzheimer drugs; Green tea, melatonin, quercetin, aerobic exercise tackle brain inflammation; Glyphosate may contribute to Alzheimer's surge; Supplements to extend sleep; A popular social media influencer makes shady claims about blood pressure supplements; Diet can influence the prognosis of early ovarian cancer; Omega-3s slow biological aging; A natural antidote to hair graying. 

Newson Health Menopause & Wellbeing Centre Playlist
293 - Navigating menopause in my 30s after ovarian cancer: Suzie's story

Newson Health Menopause & Wellbeing Centre Playlist

Play Episode Listen Later Jan 28, 2025 30:46


Joining Dr Louise Newson on this week's podcast is Suzie Aries, who shares her story of menopause following treatment for a rare and aggressive ovarian cancer in her 20s. Suzie talks about her cancer diagnosis and treatment, including raising £250,000 to fund treatment not available on the NHS. She also shares the realities of menopause at a young age, how HRT has helped her menopause symptoms, and why she takes HRT for her future health. Finally, Suzie offers advice for women on how to advocate for themselves during healthcare consultations, and why being knowledgeable, confident and curious is key. You can follow Suzie on Instagram @suzieclair11 and find out more about her story via her Facebook page Suzie Aries: kicking cancer's butt.