POPULARITY
2 episodes with adaptive immunity
2 episodes with adaptive immunity
2 episodes with adaptive immunity
2 episodes with adaptive immunity
2 episodes with adaptive immunity
2 episodes with adaptive immunity
This week's topic is The Immune System.Simply put the immune system is the body's defence against infections. The immune system attacks germs and helps keep us healthy, but it is a vastly complex system and we had lots of questions about it.This was a really interesting topic. Hopefully you learn a lot listing too.Hear us discuss:What is it?Where in the body is it?How does it work?Innate vs Adaptive Immunity.Do all living creature's immune systems work the same? Immunosuppressants Antibiotics and the immune system. Plus your Two Guys One Topic Takeaway.Once you have listened we would love to hear your thoughts or any feedback.Contact / follow us @TwoGuysOneTopic on Instagram, Twitter or Facebook to keep in touch and take part in the next "Listener Choice" episode. Hosted on Acast. See acast.com/privacy for more information.
In this episode, we review the high-yield topic of Innate vs. Adaptive Immunity from the Immunology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
Lead Story Smoking changes adaptive immunity with persistent effects Nature There is significant variability in immune response across the population, some of which is related to age, sex, and genetics, but this study examines other factors that may be related to immune response. Notably, the authors found that smoking affected both innate and adaptive immune response, and that the associations were consistent across number of years smoking and number of cigarettes. The effect on innate immune response was short-term, with immune response returning to levels comparable to non-smokers after quitting. The effect on adaptive immunity, however, was long-term and persisted even after quitting — the result of DNA methylation changes. These findings have clinical implications regarding risk of infection, cancer, and autoimmune disease in persons who smoke. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
SHOWNOTES GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/immunesystem 1:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:20 - AVALONX SUPPLEMENTS: AvalonX Supplements Are Free Of Toxic Fillers And Common Allergens (Including Wheat, Rice, Gluten, Dairy, Shellfish, Nuts, Soy, Eggs, And Yeast), Tested To Be Free Of Heavy Metals And Mold, And Triple Tested For Purity And Potency. Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist! Get 10% Off SERRAPEPTASE 125, MAGNESIUM 8 AND BERBERINE 500 At avalonx.us And mdlogichealth.com With The Code MelanieAvalon! New Customers Can Get 20% Off With Coupon Code Text "AVALONX" To 877-861-8318 And New Customers Can Get 20% Off With A Coupon Code At avalonx.us! 4:30 - FOOD SENSE GUIDE: Get Melanie's App At Melanieavalon.com/foodsenseguide To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More! 5:10 - BEAUTYCOUNTER: Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! Shop At beautycounter.com/melanieavalon For Something Magical! For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At Melanieavalon.Com/Cleanbeauty Or Text BEAUTYCOUNTER To 877-861-8318! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare! 9:05 - Heather's Background 14:40 - The History Of Infectious Disease And The Changes In Our Understanding 19:20 - What Is Immunity To A Disease? 23:00 - BONCHARGE: Blue-Light Blocking Glasses For Sleep, Stress, And Health! Go To Boncharge.Com And Use The Code Melanieavalon For 15% Off! 25:55 - The Immune System 28:00 - Is There A Central Knowledge To The Immune System? 30:25 - Is Inflammation Always Involved In An Immune Response? 32:00 - Innate And Adaptive Immune Systems 35:05 - Autoimmune Activity 35:55 - B-Cells And T-Cells 37:55 - How B-Cells Attack Viruses 40:15 - How Do Antibodies Work? 41:40 - IgM And IgG Antibodies 43:05 - The Circadian Rhythm To The Immune System 46:15 - Sleep And Inflammation 47:35 - Sleep And Vaccines 49:15 - AIRDOCTOR: Clean Your Air Of Pollutants, Viruses, Dust, And Other Toxins (Including 99.97% Of Covid) At An Incredible Price! Shop At MelanieAvalon.com/AirDoctor For Up To 50% Off All AirDoctor Units! 51:40 - TH Cell Polarization 56:30 - Allergies 59:05 - How Early Do We Develop IgE Antibodies 59:50 - Colostrum 1:01:15 - T-Cells In The Thymus 1:02:30 - Identifying The 4 Immuno-Types 1:07:20 - Inflammation And CRP 1:09:10 - Conventional & Specialized Lab Tests 1:09:25 - BLISSY: Get Cooling, Comfortable, Sustainable Silk Pillowcases To Revolutionize Your Sleep, Skin, And Hair! Once You Get Silk Pillowcases, You Will Never Look Back! Get Blissy In Tons Of Colors, And Risk-Free For 60 Nights, At Blissy.Com/Melanieavalon, With The Code Melanieavalon For 30% Off! 1:12:55 - How To Truly Boost The Immune System 1:18:00 - Sex And The Immune System 1:20:25 - How To Repair The Immune System And How Long Does It Take
SHOWNOTES GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/immunesystem 1:50 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:00 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 2:20 - AVALONX SUPPLEMENTS: AvalonX Supplements Are Free Of Toxic Fillers And Common Allergens (Including Wheat, Rice, Gluten, Dairy, Shellfish, Nuts, Soy, Eggs, And Yeast), Tested To Be Free Of Heavy Metals And Mold, And Triple Tested For Purity And Potency. Get On The Email List To Stay Up To Date With All The Special Offers And News About Melanie's New Supplements At avalonx.us/emaillist! Get 10% Off SERRAPEPTASE 125, MAGNESIUM 8 AND BERBERINE 500 At avalonx.us And mdlogichealth.com With The Code MelanieAvalon! New Customers Can Get 20% Off With Coupon Code Text "AVALONX" To 877-861-8318 And New Customers Can Get 20% Off With A Coupon Code At avalonx.us! 4:30 - FOOD SENSE GUIDE: Get Melanie's App At Melanieavalon.com/foodsenseguide To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More! 5:10 - BEAUTYCOUNTER: Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! Shop At beautycounter.com/melanieavalon For Something Magical! For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At Melanieavalon.Com/Cleanbeauty Or Text BEAUTYCOUNTER To 877-861-8318! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz Join Melanie's Facebook Group Clean Beauty And Safe Skincare With Melanie Avalon To Discuss And Learn About All The Things Clean Beauty, Beautycounter And Safe Skincare! 9:05 - Heather's Background 14:40 - The History Of Infectious Disease And The Changes In Our Understanding 19:20 - What Is Immunity To A Disease? 23:00 - BONCHARGE: Blue-Light Blocking Glasses For Sleep, Stress, And Health! Go To Boncharge.Com And Use The Code Melanieavalon For 15% Off! 25:55 - The Immune System 28:00 - Is There A Central Knowledge To The Immune System? 30:25 - Is Inflammation Always Involved In An Immune Response? 32:00 - Innate And Adaptive Immune Systems 35:05 - Autoimmune Activity 35:55 - B-Cells And T-Cells 37:55 - How B-Cells Attack Viruses 40:15 - How Do Antibodies Work? 41:40 - IgM And IgG Antibodies 43:05 - The Circadian Rhythm To The Immune System 46:15 - Sleep And Inflammation 47:35 - Sleep And Vaccines 49:15 - AIRDOCTOR: Clean Your Air Of Pollutants, Viruses, Dust, And Other Toxins (Including 99.97% Of Covid) At An Incredible Price! Shop At MelanieAvalon.com/AirDoctor For Up To 50% Off All AirDoctor Units! 51:40 - TH Cell Polarization 56:30 - Allergies 59:05 - How Early Do We Develop IgE Antibodies 59:50 - Colostrum 1:01:15 - T-Cells In The Thymus 1:02:30 - Identifying The 4 Immuno-Types 1:07:20 - Inflammation And CRP 1:09:10 - Conventional & Specialized Lab Tests 1:09:25 - BLISSY: Get Cooling, Comfortable, Sustainable Silk Pillowcases To Revolutionize Your Sleep, Skin, And Hair! Once You Get Silk Pillowcases, You Will Never Look Back! Get Blissy In Tons Of Colors, And Risk-Free For 60 Nights, At Blissy.Com/Melanieavalon, With The Code Melanieavalon For 30% Off! 1:12:55 - How To Truly Boost The Immune System 1:18:00 - Sex And The Immune System 1:20:25 - How To Repair The Immune System And How Long Does It Take
There are multiple studies that have confirmed the incredible link between the health of our microbiome - the trillions of organisms that live in our digestive tract - and our likelihood of getting viral diseases like COVID-19. A lifestyle of low fiber diets, processed foods, little connection with nature and overuse of pharmaceuticals messes up the microbiome and makes us more susceptible to viruses than we naturally would be.There is a solution to this, though: our microbiome is constantly evolving, which means we can nurture it back to health if we are struggling and we can protect it and make it even stronger even when we are well and want to stay well.My guest today, Dr. Robynne Chutkan is a board-certified gastroenterologist and author of the bestselling digestive health books Gutbliss: The Microbiome Solution, and The Bloat Cure. In her latest book, The Anti-Viral Gut: Tackling Pathogens from the Inside Out, Dr. Chutkan shares new insights and cutting edge research about our gut and our health, as well as a practical plan for strengthening the incredible antiviral defenses located in our gut and resolving symptoms of illness.Dr. Chutkan received her bachelor's from Yale University and her medical degree from Columbia College of Physicians and Surgeons, where she also did her internship and residency and served as chief resident. She completed her fellowship in gastroenterology at Mount Sinai Hospital in New York. Dr. Chutkan has been on the faculty at Georgetown University Hospital since 1997. In 2004 she founded the Digestive Center for Wellness, an integrative gastroenterology practice dedicated to uncovering the root cause of GI disorders.Dr. Chutkan incorporates microbial optimization, nutritional therapy, mind-body techniques, and lifestyle changes into her therapeutic approach to digestive disorders. Dr. Chutkan has been the medical expert on The Today Show, CBS This Morning, The Doctors, The Dr. Oz Show, The Megyn Kelly Show, and has her own PBS Special entitled “Gutbliss”.Today she will share with us her powerful and practical road map to strengthening the gut immune system.In this episode with Dr. Robynne Chutkan, you'll discover:-Social factors that inspired Robynne to write her latest book...04:30-Acid-blocking drugs compromise our immune system and gut health...09:06-The explanation of the gut and its role in our health...13:07-Innate and adaptive immunity within our bodies...22:05-Recommended tests to assess the health of your gut...30:30-A primer on the virome which allows billions of active viruses to coexist in harmony...38:10-First steps to take control of your gut and overall health...44:30-A "dirty" approach to using nature to optimize your health...47:30-Dr. Chutkan's best personal practice...54:50-And much more!Resources mentioned:Dr. Chutkan's websiteThe Anti-Viral Gut: Tackling Pathogens from the Inside OutThis Week in Virology podcastGuest's social handles:FacebookInstagramYouTube
https://psychiatry.dev/wp-content/uploads/speaker/post-11225.mp3?cb=1671193580.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Emerging roles of innate and adaptive immunity in Alzheimer’s disease – PubMed Review Xiaoying Chen et al. Immunity. 2022. Alzheimer's disease (AD)Full EntryEmerging roles of innate and adaptive immunity in Alzheimer's disease – PubMed
OncoOne is a biotech company developing novel therapeutics for patients with solid tumors and autoimmune diseases. In this podcast episode, Brent Meadows, Chief Business Officer and US General Manager, discusses the role of oxMIF in innate and adaptive immunity and outlines the company's development approach and plan for entering the clinic.
Vadim Nazarov is Co-Founder & CEO of the startup ImmunoMind. The company focuses on improving the design of adoptive T-cell therapies using multi-omics technologies. Vadim's career began at Dr. Dmitry Chudakov's Laboratory of Adaptive Immunity, where he developed the now discontinued R-package TcR. The replacement package ‘immunarch' is continuously developed by ImmunoMind. The episode is hosted by Dr. Ulrik Stervbo and Dr. Zhaoqing Ding. Comments are welcome to the inbox of onairr@airr-community.org or on social media under the hashtag #onAIRR. Further information can be found here: https://www.antibodysociety.org/the-airr-community/airr-c-podcast
Welcome to Low Carb Conversations with Leah Williamson and Holly Jean Mullen, Functional Nutritional Therapy Practitioners. Our guest this week is board certified Naturopathic Dr, Mindi Salvino. Dr. Mindi has a busy practice in Tulsa, OK where she helps patients with hormonal and thyroid issues, nutrient malabsorption, bowel and autoimmunity issues., ph correction + more! She is a leading expert in ozone and rife frequency therapy. With more than a decade of clinical experience in these treatments she has been successfully helping people overcome everything from mold toxicity and parasites to autoimmune disorders and cancers. Our discussion in this episode focuses on the importance of maintaining proper pH within the body. the right pH balance in your body reduces health risks, including bone loss, heart attacks and Alzheimer's disease. Articles: pH Balance in the Body Innate and Adaptive Immunity in the Human Intestine Connect with Dr. Mindi – The Pure Health Collective, Tulsa OK (539) 218-3611
Today Dr. Rountree and Kristi discuss a 2020 study on laser therapy and its mechanisms of “undoing” inflammatory arthritis and juvenile arthritis. Inflammatory arthritis is just one form of arthritis and it stems from an overabundance of cellular inflammatory signals without proper counterbalance of signaling. Cytokine signaling and T-cell function skew toward inflammation and tissue destruction rather than repair and healing. Laser therapy is an excellent tool for arthritis as it provides cells with photons for energy, stimulating the cellular mechanisms for repair and rejuvenation and reducing the inflammatory over-reaction. We have begun live-streaming this podcast. Watch this episode on Facebook right here. See the next episode LIVE in two weeks!Studies mentioned in this episodeMolecular and Cellular Mechanisms of Arthritis in Children and Adults: New Perspectives on Applied PhotobiomodulationYouTube ChannelLaser Therapy InstituteFurther Resources:Success with Laser Therapy Flowchart & Checklist InfographicCheck out these FREE Provider ResourcesRead about laser research on the LTI BlogLearn more about what we offer on the LTI websiteFind out how you can Customize your LTI experienceRelated Podcast for PatientsHealing at the Speed of Light
This episode covers a whole lot. Robbie is a certified Jedi— he's my go-to for all things health, and in this conversation we talk about his health story, how Neurological Networks was born, the Adaptive Immunity course, NeuroTraining, creating new neural pathways, the "root cause" of our problems as a neurological story, symptoms as the body communicating, parasites, mould, 5G, the immune system, motivation, autoimmunity, the mental/ physical/ emotional dimensions of healing, fasting, exercise, adrenals... and more! You can use code 'fullyhuman' for a discount on the Adaptive Immunity course. Check out the course here: https://tinyurl.com/adaptiveimmune
Today's episode is an interview with Andrew Verity, the creator of NeuroTraining kinesiology and the online Adaptive Immunity course. We explore how to boost your body's resilience, instead of trying to make the world you live in a "safe place". We touch on viruses, 5G, parasites, mold, and stress; what the immune system is, how to boost it, and much much more. You can check out the Adaptive Immunity course by clicking THIS LINK (or by visiting www.becomingfullyhuman.ca) If you've got questions, e-mail me at contactbecomingfullyhuman@gmail.com
More information about this and other health topics can be found in my books "Low Dose Medicine" and "Cure Without Side effects" by following these links: ►►►https://amzn.to/3Bbx8fd ►►►https://amzn.to/36iaqDU To check the Low dose Medicine health kit follow this link: ►►►https://kit.co/cureswithoutsideffect/low-dose-medicine This episode is also available as a blog post: https://cureswithoutsideffects.wordpress.com/2017/10/03/migraine-and-headaches/ DISCLAIMER: Nothing contained in this audio is intended nor can be taken to diagnose, treat, or cure any disease. It is for informational purposes only. This episode is also available as a blog post: https://cureswithoutsideffects.wordpress.com/2017/10/11/interaction-between-cytokines-and-innate-and-adaptive-immunity/ --- Send in a voice message: https://anchor.fm/cureswithoutsideeffects/message
In this episode, Julie Rubinstein, MBA, discusses her journey into the cancer space, the importance of personalized medicine and how her father's cancer diagnosis played a role in her career. Welcome to another exciting episode of Oncology Overdrive :13 About Rubinstein :19 The interview 1:53 Can you tell us a little bit about your journey into this space? 2:04 So, they were in Seattle, and you were in New York … way before this pandemic happened were you working virtually that many years ago? 11:54 When you were first in the immunotherapy space at the beginning of your career, did you guess that it would have such a huge impact in the cancer space? 14:46 How did your father's cancer diagnosis influence the way you navigated your career in the oncology space? 24:26 Discussion on the importance of personalized medicine 35:12 Rubinstein's one pearl 42:20 How to reach Rubinstein 43:35 Julie Rubinstein, MBA, is the president of Adaptive Biotechnologies. She currently oversees Life Sciences Research, Clinical Diagnostics, Drug Discovery, Corporate Marketing and Business Development functions. We'd love to hear from you! Send your comments/questions to Dr. Jain at oncologyoverdrive@healio.com. Follow us on Twitter @HemOncToday and @ShikhaJainMD. Rubinstein can be reached via email at jrubinstein@adaptivebiotech.com. Disclosures: Jain reports she is a paid freelance writer for Lippincott. Rubinstein is the president of Adaptive Biotechnologies and has stock and other ownership interests in the company.
In this episode, Eugenio, Natalie, and Jatin sit down with Dr. Claudia Jakubzick from Dartmouth University. They discus Claudia's 2018 publication that elucidated the role of natural IgM in the recognition of neoantigens in absence of PAMPs. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Immune Surveillance by Natural IgM Is Required for Early Neoantigen Recognition and Initiation of Adaptive Immunity (nih.gov)
This episode covers innate and adaptive immunity!
a very brief and basic introduction to adaptive immunity and CV-19
In this episode, I discuss about how our innate and adaptive immunity responds when bacterial or viral pathogens invade our body
https://www.cvsciences.com/https://www.youtube.com/channel/UCDSsKPMi1G2BohEsXD5lhRghttps://pubmed.ncbi.nlm.nih.gov/Sponsors:https://mybookie.com Promo Code minddoghttps://record.webpartners.co/_6_DFqqtZcLQWqcfzuvZcQGNd7ZgqdRLk/1https://apply.fundwise.com/minddoghttps://myvitalc.com/minddog. promo code minddogtvhttp://mountainmade.life
http://myvitalc.com/minddog Use promo code minddogtvSponsors: https://apply.fundwise.com/minddog
An introduction into what makes our immune system adapt and fight whatever this world can throw at us
FA 2020 - p99 Innate vs adaptive immunity
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Interactive immune systems are at the center of cancer and other diseases. In this excerpt Dr. Matthew Krummel explores how the immune system recognizes and remembers harmful bacteria. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36149]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
CARTA - Center for Academic Research and Training in Anthropogeny (Audio)
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35850]
When he was a graduate student, Dr. Ruslan Medzhitov read a theory written by Dr. Charles Janeway that foresaw the existence of a set of receptors that would directly detect pathogens and signal to T- and B-cells to generate an immune response (adaptive immunity). Medzhitov was determined to find such receptors! In this discovery talk, Dr. Ruslan Medzhitov provides a historical perspective that frames his involvement in the discovery of Toll-Like Receptors. By following the clue that NF-kB was involved in the immune response, he searched for receptors, like Toll, that had the capacity to activate NF-kB.
In 1495, a mysterious and deadly plague struck the city of Naples. Over the next 500 years, the medical attempts to understand and treat this new disease -- syphilis -- would mold and shape medicine in surprising ways. In this episode, Tony Breu and I will perform an historical and physiological biography of syphilis, covering the development of germ theory, epic poetry, mercury saunas, intentionally infecting patients with malaria, magic bullets, and lots and lots of experiments on poor rabbits. This presentation was performed live at the American College of Physicians’ national meeting in Philadelphia on April 11, 2019. Sources (WARNING -- LONG LIST): Swain, K. ‘Extraordinarily arduous and fraught with danger’: syphilis, Salvarsan, and general paresis of the insane. Lancet Psychiatry 5, (2018). Kępa, M. et al. Analysis of mercury levels in historical bone material from syphilitic subjects – pilot studies (short report). Kępa Małgorzata 69, 367-377(11) (2012). Forrai, J. Syphilis - Recognition, Description and Diagnosis. (2011). doi:10.5772/24205 Parascandola, J. From mercury to miracle drugs: syphilis therapy over the centuries. Pharm Hist 51, 14–23 (2009). Eisler, C. Who Is Dürer’s ‘Syphilitic Man’? Perspect Biol Med 52, 48–60 (2009). Rothschild, B. M. History of Syphilis. Clin Infect Dis 40, 1454–1463 (2005). Schwartz, R. S. Paul Ehrlich’s Magic Bullets. New Engl J Medicine 350, 1079–1080 (2004). Fee, E. The wages of sin. Lancet 354, SIV61 (1999). O’Shea, J. ‘Two Minutes with Venus, Two Years with Mercury’-Mercury as an Antisyphilitic Chemotherapeutic Agent. J Roy Soc Med 83, 392–395 (1989). Mahoney, J., Arnold, R., Sterner, B. L., Harris, A. & Zwally, M. Penicillin Treatment of Early Syphilis: II. Jama 251, 2005–2010 (1984). Waugh, M. Role played by Italy in the history of syphilis. Sex Transm Infect 58, 92–95 (1982). Thorburn, A. Fritz Richard Schaudinn, 1871-1906: protozoologist of syphilis. Sex Transm Infect 47, 459–461 (1971). CROSBY, A. W. The Early History of Syphilis: A Reappraisal. Am Anthropol 71, 218–227 (1969). Clark, E. G. & Danbolt, N. The Oslo study of the natural history of untreated syphilis An epidemiologic investigation based on a restudy of the Boeck-Bruusgaard material a review and appraisal. J Chron Dis 2, 311–344 (1955). MUNGER, R. S. Guaiacum, the Holy Wood from the New World. J Hist Med All Sci IV, 196–229 (1949). Thomas, E. & r, W. Rapid Treatment of Early Syphilis with Multiple Injections of Mapharsen. J Nerv Ment Dis 99, 88 (1944). WIEDER, L., FOERSTER, O. & FOERSTER, H. MAPHARSEN IN THE TREATMENT OF SYPHILIS: FURTHER EXPERIENCES. Arch Dermatol Syph 35, 402–413 (1937). THON, L. SHOULD THE INTERNIST KNOW SYPHILIS? J Amer Med Assoc 97, 994–996 (1931). Sarton, G. The Earliest Printed Literature on Syphilis, being Ten Tractates from the Years 1495-1498. Karl Sudhoff , Charles Singer , Henry E. Sigerist. Isis 8, 351–354 (1926). COLE, H., GERICKE, A. & SOLLMANN, T. THE TREATMENT OF SYPHILIS BY MERCURY INHALATIONS: HISTORY, METHOD AND RESULTS. Arch Dermatol Syph 5, 18–33 (1922). Mason, U. Observation: Use and Abuse of Salvarsan. J Natl Med Assoc 3, 340–3 (1911). Fleming, A. & Colebrook, L. ON THE USE OF SALVARSAN IN THE TREATMENT OF SYPHILIS. Lancet 177, 1631–1634 (1911). Evans, A. The Treatment of Syphilis by Salvarsan (Dioxy-diamido-arseno-benzol). Brit Med J 1, 617 (1911). Boeck, W. History, Theory and Practice of Syphilisation. New Engl J Medicine 73, 20–25 (1865). Veale, H. Remarks on Syphilis and Its Treatment. Edinb Medical J 10, 10–26 (1864). LaFond RE and Lukehart SA, Biological Basis for Syphilis. Clinical Microbiology Reviews 2006. Secher L et al, Treponema pallidum in peripheral nerve tissue of syphilitic chancres. Acta dermato-venereologica 1982. Hollander DH, Turner TB, The role of temperature in experimental treponemal infection. American journal of syphilis, gonorrhea, and venereal diseases, 1954 Eagle H, et al. The effect of hyperpyrexia on the therapeutic efficacy of penicillin in experimental syphilis. American journal of syphilis, gonorrhea, and venereal diseases, 1947. Kampmeier RH, Syphilis therapy: an historical perspective. Journal of the American Venereal Disease Association 1976. Pachner AR, Spirochetal Diseases of the CNS. Neurologic clinics, 1986. Sell S et al, Experimental syphilitic orchitis in rabbits: ultrastructural appearance of Treponema pallidum during phagocytosis and dissolution by macrophages in vivo. Laboratory investigation; a journal of technical methods and pathology, 1982. Taylor SH, Diuretics in cardiovascular therapy. Perusing the past, practising in the present, preparing for the future. Zeitschrift für Kardiologie, 1985. Ovchinnikov NM, [Treponema pallidum in peripheral nerves of rabbit syphiloma]. Vestnik dermatologii i venerologii, 1975. Cheek DB, Wu F, The Effect of Calomel on Plasma Epinephrine in the Rat and the Relationship to Mechanisms in Pink Disease, Archives of Disease in Childhood, 1959 Vogl A, The discovery of the organic mercurial diuretics, American Heart Journal, 1950 Schwemlein GX et al, Penicillin and fever therapy in early syphilis, Journal of the American Medical Association, 1948. Stringham JS, On the Diuretic Effects of Mercury in a Case of Syphilis. The Medical and physical journal, 1807 Evanson RL et al, Effect of mercurial diuretics on tubular sodium and potassium transport in the dog. The American journal of physiology, 1972 Sell S and Salman J, Demonstration of Treponema pallidum in Axons of Cutaneous Nerves in Experimental Chancres of Rabbits, Sexually Transmitted Diseases, 1992 Penn CW, Avoidance of Host Defences by Treponema pallidum in Situ and on Extraction from Infected Rabbit Testes, Microbiology 1981. Beutler B and Munford RS, Tumor Necrosis Factor and the Jarisch–Herxheimer Reaction, The New England Journal of Medicine 1996. Radolf JD et al, Treponema pallidum: doing a remarkable job with what it's got. Trends in Microbiology, 1999 Tight RR, Perkins RL, Treponema pallidum infection in subcutaneous polyethylene chambers in rabbits. Infection and immunity, 1976 Salazar JC et al, Treponema pallidum Elicits Innate and Adaptive Cellular Immune Responses in Skin and Blood during Secondary Syphilis: A Flow-Cytometric Analysis. The Journal of Infectious Diseases, 2007 Azevedo BF et al, Toxic Effects of Mercury on the Cardiovascular and Central Nervous Systems. Journal of Biomedicine and Biotechnology 2012, Clarkson TW and Magos L, The Toxicology of Mercury and Its Chemical Compounds, Critical Reviews in Toxicology 2008. Fitzgerald TJ, The Th1/Th2-like switch in syphilitic infection: is it detrimental? Infection and immunity, 1992 Batterman RC et al, THE SUBCUTANEOUS ADMINISTRATION OF MERCAPTOMERIN (THIOMERIN®): Effective Mercurial Diuretic for the Treatment of Congestive Heart Failure. Journal of the American Medical Association, 1949 Batterman RC, The status of mercurial diuretics for the treatment of congestive heart failure. American Heart Journal, 1951 Bleich HL et al, The Role of Regional Body Temperature in the Pathogenesis of Disease, The New England Journal of Medicine, 1981 Vander Veer JB et al, The Prolonged Use of an Oral Mercurial Diuretic in Ambulatory Patients with Congestive Heart Failure. Circulation 1950 Cox DL et al, The outer membrane, not a coat of host proteins, limits antigenicity of virulent Treponema pallidum. Infection and immunity, 1992. Fildes P, The Mechanism of the Anti-bacterial Action of Mercury. Br J Exp Pathol, 1940 Clarkson TW, THE MECHANISM OF ACTION OF MERCURIAL DIURETICS IN RATS; THE METABOLISM OF 203Hg‐LABELLED CHLORMERODRIN. British Journal of Pharmacology and Chemotherapy, 1965 Engelkens HJ et al, The localisation of treponemes and characterisation of the inflammatory infiltrate in skin biopsies from patients with primary or secondary syphilis, or early infectious yaws. Genitourinary Medicine, 1993 Belum GR et al, The Jarisch–Herxheimer reaction: Revisited. Travel Medicine and Infectious Disease, 2013 Arando M et al, The Jarisch–Herxheimer reaction in syphilis: could molecular typing help to understand it better? Journal of the European Academy of Dermatology and Venereology, 2018. Butler T, The Jarisch–Herxheimer Reaction After Antibiotic Treatment of Spirochetal Infections: A Review of Recent Cases and Our Understanding of Pathogenesis. The American Journal of Tropical Medicine and Hygiene, 2016 Carlson JA et al, The Immunopathobiology of Syphilis: The Manifestations and Course of Syphilis Are Determined by the Level of Delayed-Type Hypersensitivity. The American Journal of Dermatopathology 2011. Aronson IK and Soltani K, The enigma of the pathogenesis of the Jarisch-Herxheimer reaction. The British Journal of Venereal Diseases, 1976 Sellato TJ et al, The Cutaneous Response in Humans to Treponema pallidum Lipoprotein Analogues Involves Cellular Elements of Both Innate and Adaptive Immunity, The Journal of Immunology 2001 Spiller HA, Rethinking mercury: the role of selenium in the pathophysiology of mercury toxicity. Clinical Toxicology 2017 Sell S et al, Reinfection of chancre-immune rabbits with Treponema pallidum. I. Light and immunofluorescence studies. The American journal of pathology 1985. Grant SS and Hung DT, Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response, Virulence 2013 Lant AF, Modern diuretics and the kidney. Journal of Clinical Pathology, 1981 Kamath SU et al, Mercury-based traditional herbo-metallic preparations: a toxicological perspective, Archives of Toxicology 2012. Yeter et al, Mercury Promotes Catecholamines Which Potentiate Mercurial Autoimmunity and Vasodilation: Implications for Inositol 1,4,5-Triphosphate 3-Kinase C Susceptibility in Kawasaki Syndrome. Korean Circulation Journal 2013 Wöβmann W et al, Mercury intoxication presenting with hypertension and tachycardia. Archives of Disease in Childhood, 1999 Giacani L et al, Identification of the Treponema pallidum subsp. pallidum TP0092 (RpoE) Regulon and Its Implications for Pathogen Persistence in the Host and Syphilis Pathogenesis. Journal of Bacteriology 2013. Edwards AM, From tooth to hoof: treponemes in tissue‐destructive diseases. Journal of Applied Microbiology, 2003 Wolgemuth CW, Flagellar motility of the pathogenic spirochetes. Seminars in Cell & Developmental Biology 2015. Solomon HC and Kopp I, Fever Therapy. The New England Journal of Medicine 1937. Rice KM et al, Environmental Mercury and Its Toxic Effects. Journal of Preventive Medicine and Public Health 2014. Drusin LM, Electron microscopy of Treponema pallidum occurring in a human primary lesion. Journal of bacteriology 1969. McNeely MC et al, Cutaneous secondary syphilis: Preliminary immunohistopathologic support for a role for immune complexes in lesion pathogenesis. Journal of the American Academy of Dermatology 1986. Borenstein LA et al, Contribution of rabbit leukocyte defensins to the host response in experimental syphilis. Infection and immunity 1991. Cabot RC et al, Case 51-1976 — Bicentennial CPC — Syphilis, Diarrhea and Death in the 1820's. The New England Journal of Medicine 1976. Hobman JL and Crossman LC, Bacterial antimicrobial metal ion resistance. Journal of Medical Microbiology 2015 Gelpi A and Tucker JD, After Venus, mercury: syphilis treatment in the UK before Salvarsan. Sexually Transmitted Infections 2015. MacHaffie et al, A study of the effectiveness of mercurial diuretics in treatment of cardiac decompensation. The American Journal of Cardiology 1958 Aberer W et al, Ammoniated mercury ointment: outdated but still in use. Contact Dermatitis 1990 Farhi D, Dupin N, Origins of syphilis and management in the immunocompetent patient: Facts and controversies. Clinics in Dermatology (2010) 28, 533–538 Frith J, “Syphilis – Its early history and Treatment until Penicillin and the Debate on its Origins,” Journal of Military and Veterans’ Health, 20(4), retrieved online at: http://jmvh.org/article/syphilis-its-early-history-and-treatment-until-penicillin-and-the-debate-on-its-origins/ Howes OD et al, “Julius Wagner-Jauregg, 1857-1940,” American Journal of Psychiatry, April 2009 Volume 166 Number 4, Volume 166, Issue 4, April, 2009, pp. 409-409. Karamanou M et al, “Julius Wagner-Jauregg (1857-1940): Introducing fever therapy in the treatment of neurosyphilis.” Psychiatriki. 2013 Jul-Sep;24(3):208-12. Simpson WM, “Artificial fever therapy of syphilis,” JAMA. 1935;105(26):2132-2140. Tsay CJ, “Julius Wagner-Jauregg and the Legacy of Malarial Therapy for the Treatment of General Paresis of the Insane,” Yale J Biol Med. 2013;86(2): 245–254 Wagner-Jauregg J, “The history of malaria treatment of general paralysis.” Am J Psychiatry. 1946;02: 577-582 Shafer JK et al, Untreated syphilis in the male Negro: A prospective study of the effect on life expectancy. Public Health Rep. 1954 Jul; 69(7): 684–690. Abara WE et al, Syphilis Trends among Men Who Have Sex with Men in the United States and Western Europe: A Systematic Review of Trend Studies Published between 2004 and 2015. PLoS One. 2016; 11(7): e0159309. Nutton V, The Reception of Fracastoro's Theory of Contagion: The Seed That Fell among Thorns? Osiris, Vol. 6, Renaissance Medical Learning: Evolution of a Tradition (1990) Tsaraklis A, Preventing syphilis in the 16th century: the distinguished Italian anatomist Gabriele Falloppio (1523-1562) and the invention of the condom. 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Commentary by Dr. Valentin Fuster
“Being Immune to something doesn‘t mean you don‘t interact with it anymore, it means your body processes it so quickly that you don‘t have physical symptoms. Its as if your body is mastering that illness, the same process happens with your emotional system!"
Fakultät für Chemie und Pharmazie - Digitale Hochschulschriften der LMU - Teil 05/06
CRISPR/Cas is the prokaryotic adaptive immune response to viral invasion. Its mechanism is reminiscent of the eukaryotic RNA interference. The host actively incorporates short sequences from invading genetic elements (viruses or plasmids) into a region of its genome that is characterized by clustered regularly interspaced short palindromic repeats (CRISPRs) and a number of CRISPR-associated (cas) genes. The molecular memory of previous infections can be transcribed and processed into small RNAs (crRNAs) that guide a multiprotein–nucleic acid interference complex to recognize and cleave incoming foreign genetic material. Three pathways (I, II, III) are defined by their protein machinery and target specificity (DNA vs. RNA). In types I and III, the main protagonist of the interference complex is the Cas7 protein. Up to six copies of Cas7 constitute the complex’s main building block that assembles around the crRNA and provides a platform for protein interactions and target binding. During my PhD work, I solved the crystal structures of two Cas7 orthologs from different archaeal species, at 1.8 Å for Thermofilum pendens (Tp) Csc2 and at 2.37 Å for Meth- anopyrus kandleri (Mk) Csm3. The crystal structures of Mk Csm3 and Tp Csc2 were solved by experimental phasing and revealed a core RRM-like domain with a β1-α1-β2-β3-α2-β4 arrangement of secondary structure elements. The core is flanked by three peripheral domains that are defined by insertions within the core. Structural superposition of the RRM-like core domains of Mk Csm3 and Tp Csc2 with the representatives of other Cas families (5/6/7) revealed the highest homology beyond the RRM with a Cas7 family homolog. Thus I showed that Cas7 family proteins share equivalent insertions, forming homologous peripheral domains. Using the information obtained from structural data, I investigated the RNA binding properties Mk Csm3, Tp Csc2 and a Cas7 protein from subtype I-A, Thermoproteus tenax (Tt) Csa2. All orthologs bound RNA in a sequence-independent manner, according to their physiological function of spacer binding. Furthermore, a combined approach consisting of mutation analysis, UV-based protein–RNA crosslinking, mass spectrometry and fluorescence anisotropy mapped the RNA interacting regions to two structurally highly conserved positively charged surfaces. Taken together, this thesis describes a comprehensive structural study of the Cas7 family, defining the family’s structural features. These structural data from single proteins and the mapped RNA binding interfaces agree with protein–RNA interactions observed in the Escherichia coli interference complex.
Most kidney disorders involve some degree of inflammation, i.e. induction of pro-inflammatory mediators and leukocyte recruitment. But what are the factors that determine inflammation as a trigger or a consequence of kidney injury? Which types of renal inflammation can be targeted by the novel more selective immunosuppressive and anti-inflammatory agents? How to dissect the mechanisms behind innate and adaptive immune responses that are orchestrated inside or outside the kidney but both cause renal immunopathology i.e. renal inflammation? How to dissect leukocytic cell infiltrates into pro-inflammatory leukocytes from anti-inflammatory and pro-regenerative leukocytes? How to dissect leukocytes that support epithelial repair from those that promote renal fibrosis. The term `renal inflammation' has moved far beyond the descriptive category of `mixed leukocytic cell infiltrates' as commonly described in kidney biopsies. It is time to face the complexity of renal inflammation to finally benefit from the new age of novel immunomodulatory medicines.
Professor Richard Cornall tells us about his research on autoimmunity. Professor Richard Cornall aims to understand the causes of autoimmune diseases. Autoimmunity occurs when the immune system which is normally designed to attack pathogens ends up attacking the body. Professor Cornall is also interested in how people differ in their inherited susceptibility and why these differences are sustained in human populations by natural selection.
Professor Richard Cornall tells us about his research on autoimmunity. Professor Richard Cornall aims to understand the causes of autoimmune diseases. Autoimmunity occurs when the immune system which is normally designed to attack pathogens ends up attacking the body. Professor Cornall is also interested in how people differ in their inherited susceptibility and why these differences are sustained in human populations by natural selection.
Professor Richard Cornall tells us about his research on autoimmunity. Autoimmunity occurs when the immune system, which is normally designed to attack pathogens, ends up attacking the body. This can lead to a number of diseases such as diabetes and rheumatoid arthritis. Professor Richard Cornall aims to understand the causes of autoimmune disease, and also how people differ in their inherited susceptibility, and why these differences are sustained in human populations by natural selection.
Professor Richard Cornall tells us about his research on autoimmunity. Autoimmunity occurs when the immune system, which is normally designed to attack pathogens, ends up attacking the body. This can lead to a number of diseases such as diabetes and rheumatoid arthritis. Professor Richard Cornall aims to understand the causes of autoimmune disease, and also how people differ in their inherited susceptibility, and why these differences are sustained in human populations by natural selection.
Article discussion from November 15, 2011
Lecture 10 of 14: "Adaptive Immunity to Infection." Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles Michael Chair in Autoimmune Diseases, delivers a lecture course in basic immunology organized by the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. The goal of this lecture series is to provide HIV investigators with a comprehensive course in immunology. (January 2010). View all slides in separate window to follow presentation more easily.
Lecture 10 of 14: "Adaptive Immunity to Infection." Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles Michael Chair in Autoimmune Diseases, delivers a lecture course in basic immunology organized by the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. The goal of this lecture series is to provide HIV investigators with a comprehensive course in immunology. (January 2010). View all slides in separate window to follow presentation more easily.
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