Podcast appearances and mentions of nat rev neurosci

Waarom brengen pijn-prikkels, zoals zwemmen in ijskoud water, een spijkermat of een uitdagende inspanning ontspanning en geluk? En wat als de pijn-plezier balans in ons brein een beetje kapot is door de enorme toegankelijkheid van ‘instant plezier' vandaag? Kunnen we weer leren om moeilijke situaties en lastige emoties te durven ervaren? Helpt het om tijdelijk een periode weg te blijven van de snelle bevrediging die uiteindelijk tot ontevredenheid leidt?  In deze aflevering zetten we dopamine centraal.   Getuige Elise vertelt over haar ervaring met ijsberen en Eva en Maaike zoeken hun weg tussen de shaktimatten, de likes op social media en het unpacken van aan huis geleverde online bestellingen – en ze proberen daarbij helemaal hun lastige gevoelens toe te laten. De heerlijke stoot dopamine door het samen maken van deze aflevering krijgen ze er zomaar bij.    Extra bronnen:  Dit seizoen maken we samen met Breinwijzer vzw  Het boek ‘De dopamine factor' van psychiater en hoofd van de afdeling verslavingszorg aan Stanford University Dr. Anna Lembke  Hier kan je de shaktimat bestuderen  Vind een ijsberen-club in je buurt  Een overzicht van onderzoek naar de pijn-plezier balans vind je bijvoorbeeld in deze review: Leknes S, Tracey I. A common neurobiology for pain and pleasure. Nat Rev Neurosci. 2008 Apr;9(4):314-20. Of deze: Bressan RA, Crippa JA. The role of dopamine in reward and pleasure behaviour--review of data from preclinical research. Acta Psychiatr Scand Suppl. 2005;(427):14-21.   De podcastaflevering van Eos Magazine: "Ik vraag het aan" over waarom jongeren zich verwonden. 

In this episode, we're exploring the various ways stress affects your brain, both positively and negatively.We'll discuss the key differences between eustress (the beneficial kind) and distress (the harmful kind), and reveal practical strategies to manage chronic stress for better cognitive health.Whether you're dealing with daily pressures or long-term stress, this episode will arm you with knowledge to protect your brain and help you build resilience.What to Listen For:The key differences between eustress (positive stress) and distress (chronic stress).How chronic stress leads to memory loss, emotional difficulties, and increased Alzheimer's risk.The role of cortisol and the HPA axis in stress responses and brain health.How eustress boosts cognitive function, memory, and neuroplasticity.The dangers of prolonged cortisol exposure on brain structures like the hippocampus and amygdala.A study from Frontiers in Behavioral Neuroscience showing how moderate stress improves learning and memory.How chronic stress can trigger brain inflammation and accelerate cognitive decline.Practical strategies for reducing chronic stress: mindfulness meditation, social connections, and reframing stress as a positive force.The effects of chronic stress on the amygdala, prefrontal cortex, and hippocampus.Three actionable tips to protect your brain from the long-term effects of stress.Research Studies Referenced:McEwen BS (2007). "Physiology and neurobiology of stress and adaptation: central role of the brain." Physiol Rev, 87(3), 873-904. This paper explores how stress affects brain function and structure.Lupien SJ, et al. (2009). "Effects of stress throughout the lifespan on the brain, behaviour and cognition." Nat Rev Neurosci, 10(6), 434-445.Sousa N, et al. (2016). "Cortical and hippocampal circuitry changes under chronic stress: Implications for mood and cognition." Prog Neuropsychopharmacol Biol Psychiatry, 67, 1-14.Wilson, R. S., et al. (2007). "Chronic distress and incidence of mild cognitive impairment." JAMA Psychiatry, 68(2), 211-218Tang YY, et al. (2015). "The neuroscience of mindfulness meditation." Nat Rev Neurosci, 16(4), 213-225.RESOURCES: Access the FREE Masterclass: How To Optimize Your Sleep Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Join our private Facebook group: Moxie Club Meetup Follow Amy on Instagram @habitwhisperer

In this episode of Docs Talk Shop, Dr. Lemanne and Dr. Gordon explore how daily rhythms impact cancer treatment, brain health, and metabolism. Discover surprising ways to optimize your health by carefully timing your sleep, light exposure, and meals. (And think twice about late suppers!)Breast cancers spread at night, and why this means trouble if your largest meal is supper.In colorectal cancer patients, morning chemo benefits men, while afternoon chemo benefits women.Light exposure at night disrupts sleep in everyone, immediately increasing the risk of diabetes and cancer.Vigorous exercise instantly creates cancer-killing effects in the blood that last for two hours.A single night of poor sleep causes high blood glucose and junk food cravings the very next day.References:Metastatic spread of breast cancer accelerates during sleep. Nature 2022https://pubmed.ncbi.nlm.nih.gov/35732738/Reducing nighttime light exposure in the urban environment to benefit human health and society. Science. https://www.science.org/doi/epdf/10.1126/science.adg5277. Accessed September 25, 2024.Effects of anthropogenic light on health. Science. https://www.science.org/doi/10.1126/science.adg3173. Accessed September 25, 2024.Light disrupts sleep and metabolic health. NPR. https://www.npr.org/sections/health-shots/2022/04/01/1089997121/light-disrupts-sleep. Accessed September 25, 2024.Disruption of sleep due to light exposure increases insulin resistance and heart rate. PNAS. https://www.pnas.org/doi/10.1073/pnas.2113290119. Accessed September 25, 2024.West KE, Jablonski MR, Warfield B, et al. Blue light exposure suppresses melatonin and impacts circadian rhythms. J Biol Rhythms. 2015;30(6):537-546. https://pubmed.ncbi.nlm.nih.gov/30311830/. Accessed September 25, 2024.Effects of artificial light at night on human health: a review of epidemiological studies. Int J Occup Med Environ Health. 2015;28(4):563-571. https://pubmed.ncbi.nlm.nih.gov/26375320/. Accessed September 25, 2024.Chronic sleep restriction minimizes circadian disruption, preserving glucose tolerance. Diabetes Care. 2021;44(3):839-844. https://pubmed.ncbi.nlm.nih.gov/34744800/. Accessed September 25, 2024.Circadian rhythms and cognitive function. Nat Rev Neurosci. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743892/. Accessed September 25, 2024.Hall J, Rosbash M, Young M. Nobel Prize in Physiology or Medicine 2017: research on circadian rhythms. Nobel Prize Press Release. https://www.nobelprize.org/prizes/medicine/2017/press-release/. Accessed September 25, 2024.Light at night and increased stroke risk. Stroke. 2024. https://www.sciencedaily.com/releases/2024/03/240325172425.htm. Accessed September 25, 2024.Association of light exposurDawn Lemanne, MD Oregon Integrative OncologyLeave no stone unturned.Deborah Gordon, MDNorthwest Wellness and Memory CenterBuilding Healthy Brains

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.Originally released: July 18, 2017In this episode of BrainWaves, Dr. Joseph Berger discusses the complications of HIV literally from head to toe. From neuropathy to myelopathy to neurocognitive disorders as well as the myriad of opportunistic infections. Definitely worth your time.BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. The content in this episode was vetted and approved by Joseph Berger for broadcast.REFERENCESBoissé L, Gill MJ, Power C. HIV infection of the central nervous system: clinical features and neuropathogenesis. Neurol Clin 2008;26(3):799-819. PMID 18657727Di Rocco A, Simpson DM. AIDS-associated vacuolar myelopathy. AIDS Patient Care STDS 1998;12(6):457-61. PMID 11361993Dore GJ, Law MG, Brew BJ. Prospective analysis of seizures occurring in human immunodeficiency virus type-1 infection. J NeuroAIDS 1996;1(4):59-69. PMID 16873179Ellis R, Langford D, Masliah E. HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci 2007;8(1):33-44. PMID 17180161Garg RK. HIV infection and seizures. Postgrad Med J 1999;75(885):387-90. PMID 10474720Murdoch DM, Venter WD, Van Rie A, Feldman C. Immune reconstitution inflammatory syndrome (IRIS): review of common infectious manifestations and treatment options. AIDS Res Ther 2007;4:9. PMID 17488505We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

Сурсан зүйлээ хэзээ ч мартахгүйгээр цээжлэх хүсэл хүн бүрт байдаг гэдэгт хилсдэхгүй болов уу. Тэгвэл танд мэдлэгээ хэзээ ч биш юм аа гэхэд, харьцангуй удаан хугацаанд мартахгүйгээр толгойдоо хадгалж, шинэ мэдээлэлтэй уялдаа үүсгэж, илүү өргөн, далайцтайгаар бодож сурах арга зам бий, тэр арга нь та юу ч уншиж, сонсож, мэдэрсэн анхаарлаа чадах чинээндээ бүрэн төвлөрүүлэх гэдгийг танин мэдэхүйн сэтгэл судлал, тархи судлалын шинжлэх ухааны судалгааны үр дүнгүүд харуулдаг гэдгийг хэлмээр байна. Энэ үзэгдлийн физиологи үндэс, үйл ажиллагааны зарчим, хэрхэн анхаарал төвлөрөлтийг нэмэгдүүлэх, анхаарал төвлөрөлт сул байх ба ADHD-ын ялгаа зэргийг энэхүү дугаараас сонсоорой. Reference: Kühl, T., Eitel, A. Effects of disfluency on cognitive and metacognitive processes and outcomes. Metacognition Learning 11, 1–13 (2016). https://doi.org/10.1007/s11409-016-9154-x Harold Pashler, James C. Johnston, and Eric Ruthruff Annual Review of Psychology 2001 52:1, 629-651 Bean, B. The action potential in mammalian central neurons. Nat Rev Neurosci 8, 451–465 (2007). https://doi.org/10.1038/nrn2148 Morsink, S., Van der Oord, S., Antrop, I., Danckaerts, M., & Scheres, A. (2022). Studying Motivation in ADHD: The Role of Internal Motives and the Relevance of Self Determination Theory. Journal of attention disorders, 26(, 1139–1158. https://doi.org/10.1177/10870547211050948 Rapport, M. D., Alderson, R. M., Kofler, M. J., Sarver, D. E., Bolden, J., & Sims, V. (2008). Working memory deficits in boys with attention-deficit/hyperactivity disorder (ADHD): the contribution of central executive and subsystem processes. Journal of abnormal child psychology, 36(6), 825–837. https://doi.org/10.1007/s10802-008-9215-y Toplak, M. E., & Tannock, R. (2005). Time perception: modality and duration effects in attention-deficit/hyperactivity disorder (ADHD). Journal of abnormal child psychology, 33(5), 639–654. https://doi.org/10.1007/s10802-005-6743-6 Fair, D. A., Bathula, D., Nikolas, M. A., & Nigg, J. T. (2012). Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proceedings of the National Academy of Sciences of the United States of America, 109(17), 6769–6774. https://doi.org/10.1073/pnas.1115365109 Aguiar, A., Eubig, P. A., & Schantz, S. L. (2010). Attention deficit/hyperactivity disorder: a focused overview for children's environmental health researchers. Environmental health perspectives, 118(12), 1646–1653. https://doi.org/10.1289/ehp.1002326

Сурсан зүйлээ хэзээ ч мартахгүйгээр цээжлэх хүсэл хүн бүрт байдаг гэдэгт хилсдэхгүй болов уу. Тэгвэл танд мэдлэгээ хэзээ ч биш юм аа гэхэд, харьцангуй удаан хугацаанд мартахгүйгээр толгойдоо хадгалж, шинэ мэдээлэлтэй уялдаа үүсгэж, илүү өргөн, далайцтайгаар бодож сурах арга зам бий, тэр арга нь та юу ч уншиж, сонсож, мэдэрсэн анхаарлаа чадах чинээндээ бүрэн төвлөрүүлэх гэдгийг танин мэдэхүйн сэтгэл судлал, тархи судлалын шинжлэх ухааны судалгааны үр дүнгүүд харуулдаг гэдгийг хэлмээр байна. Энэ үзэгдлийн физиологи үндэс, үйл ажиллагааны зарчим, хэрхэн анхаарал төвлөрөлтийг нэмэгдүүлэх, анхаарал төвлөрөлт сул байх ба ADHD-ын ялгаа зэргийг энэхүү дугаараас сонсоорой.Reference:Kühl, T., Eitel, A. Effects of disfluency on cognitive and metacognitive processes and outcomes. Metacognition Learning 11, 1–13 (2016). https://doi.org/10.1007/s11409-016-9154-xHarold Pashler, James C. Johnston, and Eric RuthruffAnnual Review of Psychology 2001 52:1, 629-651Bean, B. The action potential in mammalian central neurons. Nat Rev Neurosci 8, 451–465 (2007). https://doi.org/10.1038/nrn2148Morsink, S., Van der Oord, S., Antrop, I., Danckaerts, M., & Scheres, A. (2022). Studying Motivation in ADHD: The Role of Internal Motives and the Relevance of Self Determination Theory. Journal of attention disorders, 26(, 1139–1158. https://doi.org/10.1177/10870547211050948Rapport, M. D., Alderson, R. M., Kofler, M. J., Sarver, D. E., Bolden, J., & Sims, V. (2008). Working memory deficits in boys with attention-deficit/hyperactivity disorder (ADHD): the contribution of central executive and subsystem processes. Journal of abnormal child psychology, 36(6), 825–837. https://doi.org/10.1007/s10802-008-9215-yToplak, M. E., & Tannock, R. (2005). Time perception: modality and duration effects in attention-deficit/hyperactivity disorder (ADHD). Journal of abnormal child psychology, 33(5), 639–654. https://doi.org/10.1007/s10802-005-6743-6Fair, D. A., Bathula, D., Nikolas, M. A., & Nigg, J. T. (2012). Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proceedings of the National Academy of Sciences of the United States of America, 109(17), 6769–6774. https://doi.org/10.1073/pnas.1115365109Aguiar, A., Eubig, P. A., & Schantz, S. L. (2010). Attention deficit/hyperactivity disorder: a focused overview for children's environmental health researchers. Environmental health perspectives, 118(12), 1646–1653. https://doi.org/10.1289/ehp.1002326Become a supporter of this podcast: https://www.spreaker.com/podcast/podlogy-podcast--4323328/support.

Mental Health ResourcesNIH Depression: https://www.nimh.nih.gov/health/topics/depression NIH Anxiety: https://www.nimh.nih.gov/health/topics/anxiety-disorders NIH Post-Traumatic Stress Disorder: https://www.nimh.nih.gov/health/topics/post-traumatic-stress-disorder-ptsd SAMHSA: https://www.samhsa.gov/ Wildflower Alliance: https://wildfloweralliance.org/NAMI: https://www.nami.org/home 988: https://988lifeline.org/ Mental Health First Aid: https://www.mentalhealthfirstaid.org/ Research StudiesAarons GA, Monn AR, Leslie LK, et al. Association between mental and physical health problems in high-risk adolescents: a longitudinal study. J Adolesc Health. 2008;43(3):260-267. doi:10.1016/j.jadohealth.2008.01.013Jacka FN. Nutritional Psychiatry: Where to Next?. EBioMedicine. 2017;17:24-29. doi:10.1016/j.ebiom.2017.02.020Lachance L, Ramsey D. Food, mood, and brain health: implications for the modern clinician. Mo Med. 2015;112(2):111-115.Opie RS, O'Neil A, Jacka FN, Pizzinga J, Itsiopoulos C. A modified Mediterranean dietary intervention for adults with major depression: Dietary protocol and feasibility data from the SMILES trial. Nutr Neurosci. 2018;21(7):487-501. doi:10.1080/1028415X.2017.1312841Parletta N, Zarnowiecki D, Cho J, et al. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED). Nutr Neurosci. 2019;22(7):474-487. doi:10.1080/1028415X.2017.1411320Gómez-Pinilla F. Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci. 2008;9(7):568-578. doi:10.1038/nrn2421Sawada T, Yokoi K. Effect of zinc supplementation on mood states in young women: a pilot study. Eur J Clin Nutr. 2010;64(3):331-333. doi:10.1038/ejcn.2009.158Evrensel A, Ceylan ME. The Gut-Brain Axis: The Missing Link in Depression. Clin Psychopharmacol Neurosci. 2015;13(3):239-244. doi:10.9758/cpn.2015.13.3.239

Dass Schlafen gar nicht so eine einfache Sache ist, wissen viele Menschen, die unter Schlafstörungen leiden. Diese komplexe Sache hat viele wichtige Funktionen - und Forschenden lange Rätsel aufgegeben. Vom Schlaflabor bis zum zirkadianen Rhythmus, von Schlafstörungen bis zu Parkinson-Therapien - Wissenschaftsjournalist Patric Seibel hat sich durch die aktuelle Forschung zum Schlaf gearbeitet. Im Gespräch mit Host Lucie Kluth erklärt er, warum Schlaf immer schon mehr getan hat, als nur den frühen Menschen davor zu bewahren, gegen im Dunkeln gegen die Höhlendecke zu laufen. Er hat Forschende dabei begleitet, erstaunliche neue Erkenntnisse zu entwickeln und erzählt von einer möglichen neuen Therapie-Methode für Parkinson-Erkrankte. Die Hintergrundinformationen: Historischer Überblick über wissenschaftliches und kulturelles Wissen über den Schlaf im 20. Jahrhundert: Ahlheim, H. Der Traum vom Schlaf im 20. Jahrhundert, Konstanz, Wallstein-Verlag 2018 Wie hängen Schlaf, Stimmung mit Licht und dem Schlaf-Wach-Rhythmus zusammen: Blume C, Garbazza C, Spitschan M. Effects of light on human circadian rhythms, sleep and mood. Somnologie (Berl). 2019 Sep; 23(3):147-156. doi: 10.1007/s11818-019-00215-x. Epub 2019 Aug 20. PMID: 31534436; PMCID: PMC6751071. Wie wir im Schlaf Erinnerungen abspeichern: Diekelmann, S, Born, J. The memory function of sleep. Nat Rev Neurosci 11, 114–126 (2010). https://doi.org/10.1038/nrn2762 Wir speichern vor allem Erinnerungen, die wir für wichtig halten: Barner, C, Werner, A-S, Schörk, S, Born, J, Diekelmann, S. The effects of sleep and targeted memory reactivation on the consolidation of relevant and irrelevant information, Sleep, 25 May 2023, Volume 2 - 2023 | https://doi.org/10.3389/frsle.2023.1187170 Christian Baumann zu Schlafqualität, Digitalisierung und Gesundheit: Baumann, C. Forum Schlaf und Digitalisierung, Universitätsspital Zürich, https://www.youtube.com/watch?v=pWixfX4d5dk, abgerufen 23.08.2023 Zum Zusammenhang zwischen verminderter Schlafqualität im Tiefschlaf und neurodegenerativen Erkrankungen wie Parkinson: Schreiner, S, Imbach, L, Valko, P, Maric, A, Maqkaj, R, Werth, E, Baumann, C, Baumann-Vogel, H. Reduced regional NREM sleep slow-wave activity is associated with cognitive impairment in Parkinson Disease, Frontiers in Neurology, 12, 2021, https://www.frontiersin.org/articles/10.3389/fneur.2021.618101, Wie wir im Schlaf lernen: Born, J. Lernen im Schlaf, ein Interview mit dem Schlafforscher Jan Born, Magazin der Techniker-Krankenkasse, https://www.tk.de/techniker/magazin/life-balance/besser-schlafen/schlaf-lernen-gedaechtnis-interview-jan-born-2059292, abgerufen 23.08.2023 Neue hirnanatomische Einblicke in die Gedächtnisbildung: Eschenko, O. Wie das Gedächtnis im Schlaf aufgebaut wird, Forschungsbericht 2012 - Max-Planck-Institut für biologische Kybernetik, https://www.mpg.de/6804083/jb_2012, abgerufen 23.08.2023 Und hier geht es zum Wissenschaftspodcast unserer Kolleg*innen vom Bayerischen Rundfunk, radioWissen: https://www.ardaudiothek.de/sendung/radiowissen/5945518/

Dass Schlafen gar nicht so eine einfache Sache ist, wissen viele Menschen, die unter Schlafstörungen leiden. Diese komplexe Sache hat viele wichtige Funktionen - und Forschenden lange Rätsel aufgegeben. Vom Schlaflabor bis zum zirkadianen Rhythmus, von Schlafstörungen bis zu Parkinson-Therapien - Wissenschaftsjournalist Patric Seibel hat sich durch die aktuelle Forschung zum Schlaf gearbeitet. Im Gespräch mit Host Lucie Kluth erklärt er, warum Schlaf immer schon mehr getan hat, als nur den frühen Menschen davor zu bewahren, gegen im Dunkeln gegen die Höhlendecke zu laufen. Er hat Forschende dabei begleitet, erstaunliche neue Erkenntnisse zu entwickeln und erzählt von einer möglichen neuen Therapie-Methode für Parkinson-Erkrankte. Die Hintergrundinformationen: Historischer Überblick über wissenschaftliches und kulturelles Wissen über den Schlaf im 20. Jahrhundert: Ahlheim, H. Der Traum vom Schlaf im 20. Jahrhundert, Konstanz, Wallstein-Verlag 2018 Wie hängen Schlaf, Stimmung mit Licht und dem Schlaf-Wach-Rhythmus zusammen: Blume C, Garbazza C, Spitschan M. Effects of light on human circadian rhythms, sleep and mood. Somnologie (Berl). 2019 Sep; 23(3):147-156. doi: 10.1007/s11818-019-00215-x. Epub 2019 Aug 20. PMID: 31534436; PMCID: PMC6751071. Wie wir im Schlaf Erinnerungen abspeichern: Diekelmann, S, Born, J. The memory function of sleep. Nat Rev Neurosci 11, 114–126 (2010). https://doi.org/10.1038/nrn2762 Wir speichern vor allem Erinnerungen, die wir für wichtig halten: Barner, C, Werner, A-S, Schörk, S, Born, J, Diekelmann, S. The effects of sleep and targeted memory reactivation on the consolidation of relevant and irrelevant information, Sleep, 25 May 2023, Volume 2 - 2023 | https://doi.org/10.3389/frsle.2023.1187170 Christian Baumann zu Schlafqualität, Digitalisierung und Gesundheit: Baumann, C. Forum Schlaf und Digitalisierung, Universitätsspital Zürich, https://www.youtube.com/watch?v=pWixfX4d5dk, abgerufen 23.08.2023 Zum Zusammenhang zwischen verminderter Schlafqualität im Tiefschlaf und neurodegenerativen Erkrankungen wie Parkinson: Schreiner, S, Imbach, L, Valko, P, Maric, A, Maqkaj, R, Werth, E, Baumann, C, Baumann-Vogel, H. Reduced regional NREM sleep slow-wave activity is associated with cognitive impairment in Parkinson Disease, Frontiers in Neurology, 12, 2021, https://www.frontiersin.org/articles/10.3389/fneur.2021.618101, Wie wir im Schlaf lernen: Born, J. Lernen im Schlaf, ein Interview mit dem Schlafforscher Jan Born, Magazin der Techniker-Krankenkasse, https://www.tk.de/techniker/magazin/life-balance/besser-schlafen/schlaf-lernen-gedaechtnis-interview-jan-born-2059292, abgerufen 23.08.2023 Neue hirnanatomische Einblicke in die Gedächtnisbildung: Eschenko, O. Wie das Gedächtnis im Schlaf aufgebaut wird, Forschungsbericht 2012 - Max-Planck-Institut für biologische Kybernetik, https://www.mpg.de/6804083/jb_2012, abgerufen 23.08.2023 Und hier geht es zum Wissenschaftspodcast unserer Kolleg*innen vom Bayerischen Rundfunk, radioWissen: https://www.ardaudiothek.de/sendung/radiowissen/5945518/

Dans ce nouvel épisode de Puls'In Vet, nous plongeons dans les mystères de l'activation des neurones mécanosensoriels, les acteurs clés qui permettent de percevoir et de ressentir le monde à travers le toucher. Pour celà, je me suis penchée sur l'article "The mechanosensory neurons of touch and their mechanisms of activation" paru dans Nature Reviews en 2021. Rejoignez-nous pour explorer les subtilités de ce processus complexe et passionnant.  Que vous soyez un vétérinaire curieux de comprendre les bases de la perception tactile ou un passionné par les avancées de la neurobiologie du toucher, cet épisode vous emmènera dans un voyage captivant au cœur des mécanismes d'activation des neurones mécanosensoriels du toucher.   Restez à l'écoute de Puls'In Vet pour en découvrir encore plus ! 

Découvrez le livre NEUROSAPIENS, sorti le 26 janvier aux éditions Les Arènes ! Pour apprendre à créer rapidement et à moindre coût son podcast, c'est par ici ! On a toujours des pensées dans notre tête. Même quand on essaye de ne penser à rien. On ne sait même pas à quoi elles ressemblent concrètement ces pensées. Elles ne sont ni matérielles, ni mesurables, ni tangibles. La question “Comment le cerveau pense-t-il ?” est une des plus grandes questions scientifiques encore non résolues à ce jour. Et pourtant, nos pensées renferment un pouvoir incroyable. Malgré qu'elles soient non palpables, elles ont un impact bien réel sur notre organisme. Nos pensées influencent notre corps et sa biochimie. Aujourd'hui, nous parlons donc de l'effet placebo. Largement étudié depuis de nombreuses années, il n'est aujourd'hui pas remis en cause. Mais comporte-t-il des limites ? Sait-on comment il fonctionne dans le cerveau ? Par quels mécanismes agit-il ? La pensée serait-elle notre meilleur médicament ?  Production, animation, réalisation et illustration : Anaïs Roux Instagram : https://www.instagram.com/neurosapiens.podcast/ neurosapiens.podcast@gmail.com Produit et distribué en association avec LACME Production. Pour apprendre à créer rapidement et à moindre coût son podcast, c'est par ici : https://www.neurosapiens.fr/commentcreerunpodcast _________ Musique  KEEP ON GOING Musique proposée par La Musique Libre Joakim Karud - Keep On Going : https://youtu.be/lOfg0jRqaA8 Joakim Karud : https://soundcloud.com/joakimkarud ONE NIGHT AWAY Musique de Patrick Patrikios _________ Sources :  Haour F. Mechanisms of the placebo effect and of conditioning. Neuroimmunomodulation. 2005;12(4):195-200. doi: 10.1159/000085651. PMID: 15990450. Wager TD, Atlas LY. The neuroscience of placebo effects: connecting context, learning and health. Nat Rev Neurosci. 2015 Jul;16(7):403-18. doi: 10.1038/nrn3976. PMID: 26087681; PMCID: PMC6013051. Dossier INSERM. Effet placebo, effet nocebo, aucun effet, vraiment ? 8 février 2022 Crum AJ, Langer EJ. Mind-set matters: exercise and the placebo effect. Psychol Sci. 2007 Feb;18(2):165-71. doi: 10.1111/j.1467-9280.2007.01867.x. PMID: 17425538

Soutenir et s'abonner à Neurosapiens Le sujet de cette semaine a été une évidence quand j'observe mon quotidien de nomade. Chaque semaine nous nous déplaçons de villes en villes en Amérique Latine et chaque semaine nous devons découvrir de nouvelles rues, de nouveaux espaces, de nouvelles directions. Comme le quotidien m'inspire beaucoup pour les épisodes de Neurosapiens, je me demande toujours dans ces moments-là s'il y a des prédispositions dans le cerveau pour la capacité d'orientation ? Comment fonctionne le GPS de notre cerveau ? Est-il similaire aux GPS technologiques ? Peut-on développer notre GPS cérébral ou est-ce une fatalité d'être mauvais en orientation ? Production, animation, réalisation et illustration : Anaïs RouxInstagram : https://www.instagram.com/neurosapiens.podcast/neurosapiens.podcast@gmail.comMusique d'intro KEEP ON GOINGMusique proposée par La Musique LibreJoakim Karud - Keep On Going : https://youtu.be/lOfg0jRqaA8Joakim Karud : https://soundcloud.com/joakimkarudSOURCESMünzer, S., Zimmer, H. D., Schwalm, M., Baus, J., & Aslan, I. (2006). Computer-assisted navigation and the acquisition of route and survey knowledge. Journal of Environmental Psychology, 26(4), 300–308. https://doi.org/10.1016/j.jenvp.2006.08.001Münzer S, Zimmer HD, Baus J. Navigation assistance: a trade-off between wayfinding support and configural learning support. J Exp Psychol Appl. 2012 Mar;18(1):18-37. doi: 10.1037/a0026553. Epub 2011 Dec 5. PMID: 22141461.Moser MB, Rowland DC, Moser EI. Place cells, grid cells, and memory. Cold Spring Harb Perspect Biol. 2015 Feb 2;7(2):a021808. doi: 10.1101/cshperspect.a021808. PMID: 25646382; PMCID: PMC4315928.Moser EI, Roudi Y, Witter MP, Kentros C, Bonhoeffer T, Moser MB. Grid cells and cortical representation. Nat Rev Neurosci. 2014 Jul;15(7):466-81. doi: 10.1038/nrn3766. Epub 2014 Jun 11. PMID: 24917300.Kropff, E., Carmichael, J., Moser, MB. et al. Speed cells in the medial entorhinal cortex. Nature 523, 419–424 (2015). https://doi.org/10.1038/nature14622Woollett, K. Talent in the taxi: A model system for exploring expertise. June 2009. Philosophical Transactions of The Royal Society B Biological Sciences 364(1522):1407-16. DOI:10.1098/rstb.2008.0288Spiers HJ, Maguire EA. A navigational guidance system in the human brain. Hippocampus. 2007;17(8):618-26. doi: 10.1002/hipo.20298. PMID: 17492693; PMCID: PMC2570439.Javadi, AH., Emo, B., Howard, L. et al. Hippocampal and prefrontal processing of network topology to simulate the future. Nat Commun 8, 14652 (2017). https://doi.org/10.1038/ncomms14652https://lejournal.cnrs.fr/articles/les-dessous-du-gps-cerebral Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out. Become a member at https://plus.acast.com/s/neurosapiens.

How and why mindfulness works. It's not woo woo. There is lots of science to support its impact. Our brain is capable of change.  Mindfulness is the path.  We welcome back Dr. Ellen Cooke, radiation oncologist, mindfulness teacher and Founder of the Circle of Hope. She shares literature covering benefits of mindfulness on hormonal regulation, neurofeedback, and epigenetics – especially amongst cancer patients.   Dr. Ni-Cheng Liang shares some of the neuroscience and neuroanatomy of how mindfulness affects the brain through attention, emotion regulation, self-awareness and pain processing. A few of the points shared in today's episode. Mindfulness can lessen the perception of pain. It improves attention, self awareness, and emotional regulation. It impacts release of hormones that affect love, sleep, healing, pain, stress, your immune response and mood disorders. Mindfulness has been shown in studies to lessen stress by measurements of hormones. This episode hopefully will serve as inspiration to recommit to daily mindfulness practice as an evidence-based way to help ourselves.   Some of the articles referenced in this episode:  Tang, YY., Hölzel, B. & Posner, M. The neuroscience of mindfulness meditation. Nat Rev Neurosci 16, 213–225 (2015). https://doi.org/10.1038/nrn3916 We'd love to connect with you and invoke some of these physiologic benefits of mindfulness at our first-ever Mindful Healers: Connect in Nature retreat where we will be practicing and embodying mindful living together. Learn more & Sign up here https://www.jessiemahoneymd.com/retreat-connect-in-nature You can learn more about Dr. Cooke here:  www.jointhecircleofhope.com CUREate Your Mind Facebook Group: www.facebook.com/groups/585699575506999 @circleofhope4u If you want to find calm, contentment, and a clear and meaningful path forward in areas of your life beyond relationships, I invite you to explore private mindful coaching with Dr. Mahoney www.jessiemahoneymd.com If you want to develop a mindfulness practice, reach out to Dr. Liang www.awakenbreath.org *Nothing in this episode should be considered medical advice.

Weight gain during the holidaysIs it real?Discussion of the researchEat more protein4x40 or 4x30 approachRelax on the big dayHedonic and homeostatic reasons to eatGo moveWalk or exerciseDaily body weight measurementsResearchMore water and electrolytesRelationship between hunger and thirstGetting salt is mainly done via eatingCraving salty foodsResearchAffiliate link: Drink LMNT | Paleo-Keto Friendly Hydration | Zero Sugar Electrolytes – Drink The Flex Diet Podcast is brought to you by the Flex Diet Certification. Go to https://flexdiet.com/ for 8 interventions on nutrition and recovery. If you're outside the enrollment window, sign up for my free newsletter, and you'll be notified when it opens!ReferencesHoliday Weight Gain?Díaz-Zavala, R. G., Castro-Cantú, M. F., Valencia, M. E., Álvarez-Hernández, G., Haby, M. M., & Esparza-Romero, J. (2017). Effect of the Holiday Season on Weight Gain: A Narrative Review. Journal of obesity, 2017, 2085136. https://doi.org/10.1155/2017/2085136https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514330/Roberts SB, Mayer J. Holiday weight gain: fact or fiction? Nutr Rev. 2000 Dec;58(12):378-9. doi: 10.1111/j.1753-4887.2000.tb01839.x. PMID: 11206847.https://pubmed.ncbi.nlm.nih.gov/11206847/Kaviani S, vanDellen M, Cooper JA. Daily Self-Weighing to Prevent Holiday-Associated Weight Gain in Adults. Obesity (Silver Spring). 2019 Jun;27(6):908-916. doi: 10.1002/oby.22454. PMID: 31119881.https://pubmed.ncbi.nlm.nih.gov/31119881/Protein EffectsWesterterp-Plantenga MS, Lemmens SG, Westerterp KR. Dietary protein - its role in satiety, energetics, weight loss and health. Br J Nutr. 2012 Aug;108 Suppl 2:S105-12. doi: 10.1017/S0007114512002589. PMID: 23107521.https://pubmed.ncbi.nlm.nih.gov/23107521/Cuenca-Sánchez M, Navas-Carrillo D, Orenes-Piñero E. Controversies surrounding high-protein diet intake: satiating effect and kidney and bone health. Adv Nutr. 2015 May 15;6(3):260-6. doi: 10.3945/an.114.007716. PMID: 25979491; PMCID: PMC4424780.https://pubmed.ncbi.nlm.nih.gov/25979491/Phillips SM, Chevalier S, Leidy HJ. Protein "requirements" beyond the RDA: implications for optimizing health. Appl Physiol Nutr Metab. 2016 May;41(5):565-72. doi: 10.1139/apnm-2015-0550. Epub 2016 Feb 9. PMID: 26960445.https://pubmed.ncbi.nlm.nih.gov/26960445/Non-exercise activity thermogenesisLevine JA. Non-exercise activity thermogenesis (NEAT). Best Pract Res Clin Endocrinol Metab. 2002 Dec;16(4):679-702. doi: 10.1053/beem.2002.0227. PMID: 12468415.https://pubmed.ncbi.nlm.nih.gov/30370831/Malaeb S, Perez-Leighton CE, Noble EE, Billington C. A "NEAT" Approach to Obesity Prevention in the Modern Work Environment. Workplace Health Saf. 2019 Mar;67(3):102-110. doi: 10.1177/2165079918790980. Epub 2018 Oct 29. PMID: 30370831.https://pubmed.ncbi.nlm.nih.gov/12468415/Hunger and ThirstAugustine V, Lee S, Oka Y. Neural Control and Modulation of Thirst, Sodium Appetite, and Hunger. Cell. 2020 Jan 9;180(1):25-32. doi: 10.1016/j.cell.2019.11.040. PMID: 31923398; PMCID: PMC7406138.https://pubmed.ncbi.nlm.nih.gov/31923398/Bray N. A taste for hunger and thirst. Nat Rev Neurosci. 2020 Nov;21(11):592-593. doi: 10.1038/s41583-020-00380-1. PMID: 32913320.https://pubmed.ncbi.nlm.nih.gov/32913320/Mattes RD. Hunger and thirst: issues in measurement and prediction of eating and drinking. Physiol Behav. 2010 Apr 26;100(1):22-32. doi: 10.1016/j.physbeh.2009.12.026. Epub 2010 Jan 11. PMID: 20060847; PMCID: PMC2849909.https://pubmed.ncbi.nlm.nih.gov/20060847/McKiernan F, Houchins JA, Mattes RD. Relationships between human thirst, hunger, drinking, and feeding. Physiol Behav. 2008 Aug 6;94(5):700-8. doi: 10.1016/j.physbeh.2008.04.007. Epub 2008 Apr 13. PMID: 18499200; PMCID: PMC2467458.https://pubmed.ncbi.nlm.nih.gov/18499200/McKiernan F, Hollis JH, McCabe GP, Mattes RD. Thirst-drinking, hunger-eating; tight coupling? J Am Diet Assoc. 2009 Mar;109(3):486-90. doi: 10.1016/j.jada.2008.11.027. PMID: 19248867; PMCID: PMC2671201.https://pubmed.ncbi.nlm.nih.gov/19248867/ 

This is the final episode of the six part series, "Making Headway with Your Inner Dialogue: 6 Ways to Take Charge of Your Inner Critic."     Series 1: Episode 6 In this episode, Dr. Dee discusses:How is it defined?What is personal agency theory?How does having personal agency benefit youWhat is the difference between hypo and hyperagency?The ten steps to achieveKey Takeaways:Personal agency helps people choose their own paths and influence short-term outcomes plus longer-term destinies. Bandura's social cognitive theory identifies the core belief in personal agency as self-efficacy—confidence in our ability to perform a task or achieve a goalYou are responsible for your thoughts which create your feelings and emotionsThere are key steps to achieve Owning Your Space:Find your avatar valuesUse your voice assertivelyControl StimuliAssociate SelectivelyGet ActivePosition Yourself as a LearnerManage Your Emotions and BeliefsDeliberate, Then ActConnect to ResourcesPractice mindfulness “Owning your space is building an empowering consistent inner dialogue that inspires you to be bold, practice compassion and lean into mastering your awareness of your journey”-Dr. Dee Recommended Resources:Alper S. (2020) Personal Agency. In: Zeigler-Hill V., Shackelford T.K. (eds) Encyclopedia of Personality and Individual Differences. Springer, Cham. https://doi.org/10.1007/978-3-319-24612-3_1871Bandura, A. Self-efficacy mechanism in human agency. Am. Psychol.37, 122–147 (1982).Bandura, A. (2000). Exercise of human agency through collective efficacy. Current Directions in Psychological Science, 9, 75–78.  https://doi.org/10.1111/1467-8721.00064.CrossRefGoogle ScholarBandura, A. (2006). Toward a psychology of human agency. Perspectives on Psychological Science, 1, 164–180.  https://doi.org/10.1111/j.1745-6916.2006.00011.x.Haggard, P. Sense of agency in the human brain. Nat Rev Neurosci 18, 196–207 (2017). https://doi.org/10.1038/nrn.2017.14Napper and Rao, et. Al. (2019).The Power of Agency: The 7 Principles to Conquer Obstacles, Make Effective Decisions, and Create a Life on Your Own Terms. Macmillan Audio Connect with Dr. Dee: Website: BlueEggLeadership.comLinkedIn: linkedin.com/in/drtrudeau

WTF is Interoceptive Awareness?  Interoception involves communication between a bodily sensation and our brain processing the information to support physical and emotional wellbeing, and ultimately a response.  The ability to access interoceptive awareness varies greatly from person to person; for some it is relatively easy and little guidance is needed and for others, it can take training and practice.  Any type of conscious restriction causes us to detach from our body signals and ignore what is happening. The disconnect causes us to be confused and unable to read what our body is actually telling us.  In this episode, we discuss how Intuitive Eating helps us tap into our interoceptive awareness. MENTIONS Craig, A. D. (2009). How do you feel--now? The anterior insula and human awareness. Nat Rev Neurosci, 10(1), 59-70. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985305/ SHOW SPONSORS If you're ready to give it a try, Online Therapy.com is providing an exclusive offer to our listeners for 20% off your first month. Stitch Fix:  Ready to try it out? Get $25 off your first fix!  Just Thrive Probiotics - Get 15% off your first order using code: tonyabythespoonful CTA If what we shared today resonated with you and you want a space to explore this further, click the link in our show notes to sign up for a free discovery call here.   Subscribe to our Newsletter Follow Us: Instagram and share your "Wait, what?" moments with us. Have an idea for an upcoming episode? Let us know on our Facebook page.

Newsletter: https://dralkapatel.com/mailinglist "How to integrate ancient Eastern traditions into modern healthcare practices?” My guest on this week's episode of The Lifestyle First Podcast is Dr Carolyn Rubens. Carolyn is a GP and Lifestyle Medicine Practitioner and former President of the British Medical Acupuncture Society. We discuss the meaning of holistic health. We explore the application of acupuncture. We highlight where acupuncture may be useful We talk about how to find an acupuncturist 1. The one question we discuss is “How to integrate ancient eastern traditions into modern healthcare practices?” 2. The two references we look at are: DeCabo R et al, Effects of Intermittent Fasting on Health, Aging and Disease, 2019, NEJM, 381:2541-2551 https://www.nejm.org/doi/full/10.1056/NEJMra1905136 Mattson MP et al, Intermittent metabolic Switching, neuroplasticity and brain health. Nat Rev Neurosci 2018; 19:63-80 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913738/ 3. The three actions to take are · Choose achievable small goals · Do something you enjoy everyday · Prioritise your own needs first then you have more to give from your cup Which of these 3 actionable health tips will you implement? Leave your comments below. -x- 1. A Prescription for Healthy Living. Available on Amazon https://www.amazon.co.uk/Prescription-Healthy-Living-Lifestyle-Medicine/dp/0128215739/ref=sr_1_2?crid=3VLHX0B1Q0B7M&dchild=1&keywords=a+prescription+for+healthy+living&qid=1608562418&sprefix=prescription+for+healthy+%2Caps%2C152&sr=8-2 2. Join The Lifestyle First Academy! Take the flagship course – Start Now: Transform your Lifestyle to Transform your Life -x- DISCLAIMER: This content does not constitute or substitute personal one-to-one professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or health care professional with questions about your health. -x- Find Out More/Contact/Follow: Guest: Instagram: https://www.instagram.com/dr_carolynrubens/ Newsletter: https://dralkapatel.com/mailinglist Website: https://dralkapatel.com/ Social: https://www.facebook.com/dralkapateluk https://www.facebook.com/LifestyleFirstUK https://www.facebook.com/groups/lifestylefirstevolution https://www.instagram.com/dralkapateluk https://www.linkedin.com/in/dralkapateluk/ https://twitter.com/dralkapateluk YouTube: https://www.youtube.com/channel/UCaQrM4ryE0a38zqsednEppQ Podcast: https://anchor.fm/dr-alka-patel --- Send in a voice message: https://anchor.fm/dr-alka-patel/message

Newsletter: https://dralkapatel.com/mailinglist Is fasting safe and why should I try it? Fasting has been embedded into cultures for centuries and research is now uncovering the health benefits of fasting. My guest on this week's episode of The Lifestyle First Podcast is Dr Ellen Fallows. Ellen is a GP and person-centred lead with the Royal College of GPs and also delivering NHS programmes to reverse high blood pressure and diabetes. We discuss the definition of fasting and various formats for fasting We highlight how fasting is not essential for survival but also a tool for surviving well. We talk about metabolic switching from using sugar as fuel to using the breakdown products of fat as fuel (ketones) And we uncover some data suggesting fasting may prime our immune systems to work more effectively against Covid19 1. The one question we discuss is “IS fasting safe and why should I try it?” 2. The two references we look at are: o DeCabo R et al, Effects of Intermittent Fasting on Health, Aging and Disease, 2019, NEJM, 381:2541-2551 https://www.nejm.org/doi/full/10.1056/NEJMra1905136 o Mattson MP et al, Intermittent metabolic Switching, neuroplasticity and brain health. Nat Rev Neurosci 2018; 19:63-80 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913738/ 3. The three actions to take are o Snack: don't' snack o Swap: Eat leafy green veg and beans in place of processed food. o Squish – reduce the time window during which you eat – try a later breakfast or an earlier dinner Which of these 3 actionable health tips will you implement? Leave your comments below. -x- 1. A Prescription for Healthy Living. Available on Amazon https://www.amazon.co.uk/Prescription-Healthy-Living-Lifestyle-Medicine/dp/0128215739/ref=sr_1_2?crid=3VLHX0B1Q0B7M&dchild=1&keywords=a+prescription+for+healthy+living&qid=1608562418&sprefix=prescription+for+healthy+%2Caps%2C152&sr=8-2 2. Join The Lifestyle First Academy! Take the flagship course – Start Now: Transform your Lifestyle to Transform your Life Use code JAN24 for your 24% discount up to 24th January https://dralkapatel.com/academy/ -x- DISCLAIMER: This content does not constitute or substitute personal one-to-one professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or health care professional with questions about your health. -x- Find Out More/Contact/Follow me: Newsletter: https://dralkapatel.com/mailinglist Website: https://dralkapatel.com/ Social: https://www.linkedin.com/in/dralkapateluk/ https://www.facebook.com/dralkapateluk https://www.instagram.com/dralkapateluk https://twitter.com/dralkapateluk --- Send in a voice message: https://anchor.fm/dr-alka-patel/message

⟩⟩ Emotionaler Schmerz (z.B.: Trauer, Einsamkeit, Ablehnung) ist für viele Menschen kein angenehmes Gefühl. Im Gegenteil: wir tun oft alles, um diesem Gefühl komplett aus dem Weg zu gehen. Auf eine gewissen Weise ist sogar unser gesamtes (reaktives) Enneagramm-Muster dienlich, um uns vor emotionalem Schmerz zu bewahren. Wir wollen darüber sprechen (inkl. einiger Studien) wie diese Emotionswelt unseren Körper physisch verändert, welche Relevanz sie für uns hat und wie wir am besten damit umgehen können. --- Quellen: - How your emotions change the shape of your heart | Sandeep Jauhar -- https://youtu.be/mwoLhdHRt_0 - Hidden Brain — You 2.0: The Empathy Gym — July 29, 20193:00 PM ET https://www.npr.org/2019/07/22/744195502/you-2-0-the-empathy-gym — https://www.npr.org/transcripts/744195502 - Hidden Brain — ep. 68 „Schadenfacebook“ — https://www.npr.org/templates/transcript/transcript.php?storyId=524005057 - Hidden Brain — Looking Back - https://www.npr.org/2018/06/21/622298227/radio-replay-looking-back - Francesco Pelliccia, Juan Carlos Kaski, Filippo Crea, and Paolo G. Camici. Pathophysiology of Takotsubo Syndrome. Originally published13 Jun 2017https://doi.org/10.1161/CIRCULATIONAHA.116.027121 — https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.116.027121 - Christian Templin, Jürgen Hänggi, Carina Klein, Marlene S Topka, Thierry Hiestand, Rena A Levinson, Stjepan Jurisic, Thomas F Lüscher, Jelena-Rima Ghadri, Lutz Jäncke. Altered limbic and autonomic processing supports brain-heart axis in Takotsubo syndrome. European Heart Journal, Volume 40, Issue 15, 14 April 2019, Pages 1183–1187, https://doi.org/10.1093/eurheartj/ehz068 — https://academic.oup.com/eurheartj/article/40/15/1183/5366976/ - Aron, Arthur, Helen Fisher, Debra J. Mashek, Greg Strong, Haifang Li, and Lucy L. Brown. Reward, motivation, and emotion systems associated with early-stage intense romantic love. J Neurophysiol 94: 327–337, 2005; doi:10.1152/jn.00838.2004 — http://web.mit.edu/fustflum/documents/papers/love.pdf - Hsu, D. T., Sanford, B. J., Meyers, K. K., Love, T. M., Hazlett, K. E., Wang, H., … Zubieta, J.-K. (2013). Response of the μ-opioid system to social rejection and acceptance. Molecular Psychiatry, 18(11), 1211–1217. doi:10.1038/mp.2013.96 — http://sci-hub.tw/10.1038/mp.2013.96 - Starr CJ, Sawaki L, Wittenberg GF, et al. Roles of the insular cortex in the modulation of pain: insights from brain lesions. J Neurosci. 2009;29(9):2684–2694. doi:10.1523/JNEUROSCI.5173-08.2009 — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748680/ - Eisenberger NI. The pain of social disconnection: examining the shared neural underpinnings of physical and social pain. Nat Rev Neurosci. 2012 May 3;13(6):421-34. doi: 10.1038/nrn3231. — https://www.ncbi.nlm.nih.gov/pubmed/22551663 — http://icpla.edu/wp-content/uploads/2016/10/Eisenberger-N.-The-Pain-of-Social-Disconnection-Examining-the-shared-neural-underpinnings-of-physical-and-social-pain.pdf - Eisenberger NI. The neural bases of social pain: evidence for shared representations with physical pain. Psychosom Med. 2012;74(2):126–135. doi:10.1097/PSY.0b013e3182464dd1 -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273616/ - Segerstrom, S. C., & Miller, G. E. (2004). Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry. Psychological Bulletin, 130(4), 601–630. doi:10.1037/0033-2909.130.4.601 — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361287/ - Cannon WB. "Voodoo" death. American Anthropologist, 1942;44(new series):169-181. Am J Public Health. 2002 Oct;92(10):1593-6; discussion 1594-5. PMID: 12356599. PMC1447285. DOI: 10.2105/ajph.92.10.1593 https://doi.org/10.1525/aa.1942.44.2.02a00010 --- ⟩⟩ Fragen und Anregungen zum Podcast: podcast@enneagramgermany.de

Dans cet épisode un peu spécial, @Heal You vous plonge dans des histoires extraordinaires de médecine. Ces hommes et femmes ont révolutionné le monde de la médecine et… ce n'était pas toujours volontaire !  Histoire n°1 – Le lendemain de son opération du cerveau, en 1953, Henri Molaison se réveille sans aucun souvenir. Mais il y a pire. A partir de la date de son opération, le jeune homme de 27 ans sera incapable de créer de nouveaux souvenirs. Et cela jusqu'à la fin de sa vie, en 2008. Découvrez l'histoire de cet homme qui a, malgré lui, participé aux plus grandes découvertes sur la mémoire du 20ème siècle.  Histoire n°2 – Nous sommes au début de la Première guerre Mondiale. Fin 1914, un groupe de femmes écossaises et médecins embarquent direction la France. Elles s'installent dans l'Abbaye de Royaumont, pas loin de la ligne de front. Elles y montent en quelques jours un hôpital militaire entièrement composé de femmes bénévoles. Il sera seul à fonctionner en continu de janvier 1915 à mars 1919.  Comme d'habitude, voici les sources que j'ai utilisé pour écrire cet épisode:  Histoire n°1  Dossani RH, Missios S, Nanda A, The legacy of Henry Molaison (1926-2008) and the impact of his bilateral mesial temporal lobe surgery on the study of human memory, World Neurosurgery (2015), doi: 10.1016/j.wneu.2015.04.031.  Henry Molaison Le cas HM, Neuropsy Chovlog Larry R. Squire, The Legacy of Patient H.M. for Neuroscience, Neuron. 2009 January 15; 61(1): 6–9. doi:10.1016/j.neuron.2008.12.023. Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM, Thiebaut De Schotten M, et al. From phineas gage and monsieur leborgne to H.M.: revisiting disconnection syndromes. Cereb Cortex. (2015) 25:4812–27. 10.1093/cercor/bhv173  Annese, J. et al. Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction. Nat. Commun. 5:3122 doi: 10.1038/ncomms4122 (2014). Corkin, S. What's new with the amnesic patient H.M.?. Nat Rev Neurosci 3, 153–160 (2002). https://doi.org/10.1038/nrn726 Histoire n°2 Band of sisters: the female doctors who became war heroes against the odds, Chris Holme freelance historian, BMJ 2019;367:l6747, 17 December 2019. M-F Weiner, The Scottish Women’s Hospital at Royaumont, France 1914–1919, Journal of the Royal College of Physicians of Edinburgh, vol.44, 2014 1914 – 1919 : le Scottish Women’s Hospital de Royaumont  1914 - 1918 : Royaumont dans la Grande Guerre - Royaumont in the "Great War" #Womenswork100: The Scottish Women’s Hospital at Royaumont Crédits · Logo: sousX  · Musique:  Julien Loisy

Dans cet épisode un peu spécial, @Heal You vous plonge dans des histoires extraordinaires de médecine. Ces hommes et femmes ont révolutionné le monde de la médecine et… ce n'était pas toujours volontaire !  Histoire n°1 – Le lendemain de son opération du cerveau, en 1953, Henri Molaison se réveille sans aucun souvenir. Mais il y a pire. A partir de la date de son opération, le jeune homme de 27 ans sera incapable de créer de nouveaux souvenirs. Et cela jusqu'à la fin de sa vie, en 2008. Découvrez l'histoire de cet homme qui a, malgré lui, participé aux plus grandes découvertes sur la mémoire du 20ème siècle.  Histoire n°2 – Nous sommes au début de la Première guerre Mondiale. Fin 1914, un groupe de femmes écossaises et médecins embarquent direction la France. Elles s'installent dans l'Abbaye de Royaumont, pas loin de la ligne de front. Elles y montent en quelques jours un hôpital militaire entièrement composé de femmes bénévoles. Il sera seul à fonctionner en continu de janvier 1915 à mars 1919.  Comme d'habitude, voici les sources que j'ai utilisé pour écrire cet épisode:  Histoire n°1  Dossani RH, Missios S, Nanda A, The legacy of Henry Molaison (1926-2008) and the impact of his bilateral mesial temporal lobe surgery on the study of human memory, World Neurosurgery (2015), doi: 10.1016/j.wneu.2015.04.031.  Henry Molaison Le cas HM, Neuropsy Chovlog Larry R. Squire, The Legacy of Patient H.M. for Neuroscience, Neuron. 2009 January 15; 61(1): 6–9. doi:10.1016/j.neuron.2008.12.023. Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM, Thiebaut De Schotten M, et al. From phineas gage and monsieur leborgne to H.M.: revisiting disconnection syndromes. Cereb Cortex. (2015) 25:4812–27. 10.1093/cercor/bhv173  Annese, J. et al. Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction. Nat. Commun. 5:3122 doi: 10.1038/ncomms4122 (2014). Corkin, S. What's new with the amnesic patient H.M.?. Nat Rev Neurosci 3, 153–160 (2002). https://doi.org/10.1038/nrn726 Histoire n°2 Band of sisters: the female doctors who became war heroes against the odds, Chris Holme freelance historian, BMJ 2019;367:l6747, 17 December 2019. M-F Weiner, The Scottish Women’s Hospital at Royaumont, France 1914–1919, Journal of the Royal College of Physicians of Edinburgh, vol.44, 2014 1914 – 1919 : le Scottish Women’s Hospital de Royaumont  1914 - 1918 : Royaumont dans la Grande Guerre - Royaumont in the "Great War" #Womenswork100: The Scottish Women’s Hospital at Royaumont Crédits · Logo: sousX  · Musique:  Julien Loisy

In Episode 15 sprechen Patrick und ich über den Schlaf. Was macht diesen so wertvollen Prozess eigentlich aus? Wieso sind wir zurzeit so wenig am schlafen und wie könnt ihr euren Schlaf verbessern? Ein gesunder Schlaf ist nicht selbstverständlich. Die moderne Kultur beeinflusst unsere Schlafqualität und Schlafquantität enorm. Nicht nur durch die viele Lichtverschmutzung, sondern auch durch den ständigen chronischen Stress, die immer früher werdenden Schul- und Arbeitszeiten. Schlaf ist das Schweizer Armeemesser der Gesundheit, es beinahe keine gesundheitlichen Aspekte, die vom Schlaf nicht beeinflusst werden. Pflegt ihn also, denn ein Schlafdefizit über Jahre hinweg hat mehr negative Effekte als nur Kopfschmerzen und Unkonzentriertheit.  Why we sleep - Matthew Walker Walker, Matthew P. Sleep-dependent memory processing. Harvard review of psychiatry 16.5 (2008): 287-298. https://www.tandfonline.com/doi/abs/10.1080/10673220802432517 Sleep to Remember: The brain needs sleep before and after learning new things, regardless of the type of memory. Naps can help, but caffeine isn't an effective substitute. Vol. 94, No. 4 https://www.jstor.org/stable/27858801?seq=1 Krause, A. et al., The sleep-deprived human brain.Nat Rev Neurosci. 2017 Jul;18(7):404-418. https://www.ncbi.nlm.nih.gov/pubmed/28515433 Bryce et. al., Sleep: A novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease? Trends Neurosci. 2016 Aug; 39(8): 552–566.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967375/ Wei, Y. et al. Insomnia Really Hurts: Effect of a Bad Night's Sleep on Pain Increases With Insomnia Severity. Front Psychiatry. 2018; 9: 377. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121188/

Manipolare il microbioma per migliorare il tono dell’umore? Per stabilizzare l’umore? Per migliorare schizofrenia, autismo e altre psicopatologie? Sembra che gli studi sulla psicobiotica indichino questa strada molto ambiziosa ed inaspettata.Chi mi segue sa che tratto gli argomenti inerenti la psicobiotica da diverso tempo e che i rapporti tra microbioma e psichiatria sono molto presenti su questo canale YouTube e sul mio blog https://www.valeriorosso.com.In questo breve video riassumo i concetti di base della psicobiotica, ovvero di come il nostro microbioma influenza la nostra mente e viceversa. Per maggiori informazioni vi consiglio questi altri miei video:https://youtu.be/WrdUwTPFUTshttps://youtu.be/hJ1d8o4kbbsInvece sul mio blog vi consiglio di visitare tutta la sezione sulla psicobiotica:https://www.valeriorosso.com/psicobio...ISCRIVETEVI AL MIO CANALE ► https://bit.ly/2zGIJorVi interessano la Psichiatria e le Neuroscienze? Bene, allora iscrivetevi a questo podcast, al mio canale YouTube e seguitemi sul web tramite il mio blog https://www.valeriorosso.comInoltre andate su Amazon a dare un’occhiata ai miei libri:“Psicobiotica” - Un nuovo modo di intendere il rapporto tra la Mente ed il Corpo….andate su: https://amzn.to/2IZwjhm“Psichiatria Rock” - 50 pensieri off line dal mio blog….andate su: https://amzn.to/2IVKKmJBibliografia:Gómez-Eguílaz M, Ramón-Trapero JL, Pérez-Martínez L, Blanco JR. The beneficial effect of probiotics as a supplementary treatment in drug-resistant epilepsy: a pilot study. Benef Microbes. 2018;9:875-881.Liu J, Wan GB, Huang MS, et al. Probiotic therapy for treating behavioral and gastrointestinal symptoms in autism spectrum disorder: a systematic review of clinical trials. Curr Med Sci. 2019;39:173-184.Ng QX, Soh AY, Venkatanarayanan N, Ho CY, Lim DY, Yeo WS. A systematic review of the effect of probiotic supplementation on schizophrenia symptoms. Neuropsychobiology. 2019;78:1-6.Fusar-Poli L, Surace T, Vanella A, et al. The effect of adjunctive nutraceuticals in bipolar disorder: A systematic review of randomized placebo-controlled trials. J Affect Disord. 2019;252:334-349.Leblhuber F, Steiner K, Schuetz B, Fuchs D, Gostner JM. Probiotic supplementation in patients with Alzheimer's dementia—an explorative intervention study. Curr Alzheimer Res. 2018;15:1106-1113.Wang H, Lee IS, Braun C, Enck P. Effect of probiotics on central nervous system functions in animals and humans: a systematic review. J Neurogastroenterol Motil. 2016;22:589-605.Mayer EA. Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci. 2011;12:453-466.Kazemi A, Noorbala AA, Azam K, Eskandari MH, Djafarian K. Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: a randomized clinical trial. Clin Nutr. 2019;38:522-528.Gondalia S, Parkinson L, Stough C, Scholey A. Gut microbiota and bipolar disorder: a review of mechanisms and potential targets for adjunctive therapy. Psychopharmacology (Berl). 2019 Apr 30.Johnson KV, Foster KR. Why does the microbiome affect behaviour? Nat Rev Microbiol. 2018;16:647-655.Huang R, Wang K, Hu J. Effect of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials. Nutrients. 2016;8.

Manipolare il microbioma per migliorare il tono dell’umore? Per stabilizzare l’umore? Per migliorare schizofrenia, autismo e altre psicopatologie? Sembra che gli studi sulla psicobiotica indichino questa strada molto ambiziosa ed inaspettata.Chi mi segue sa che tratto gli argomenti inerenti la psicobiotica da diverso tempo e che i rapporti tra microbioma e psichiatria sono molto presenti su questo canale YouTube e sul mio blog https://www.valeriorosso.com.In questo breve video riassumo i concetti di base della psicobiotica, ovvero di come il nostro microbioma influenza la nostra mente e viceversa. Per maggiori informazioni vi consiglio questi altri miei video:https://youtu.be/WrdUwTPFUTshttps://youtu.be/hJ1d8o4kbbsInvece sul mio blog vi consiglio di visitare tutta la sezione sulla psicobiotica:https://www.valeriorosso.com/psicobio...ISCRIVETEVI AL MIO CANALE ► https://bit.ly/2zGIJorVi interessano la Psichiatria e le Neuroscienze? Bene, allora iscrivetevi a questo podcast, al mio canale YouTube e seguitemi sul web tramite il mio blog https://www.valeriorosso.comInoltre andate su Amazon a dare un’occhiata ai miei libri:“Psicobiotica” - Un nuovo modo di intendere il rapporto tra la Mente ed il Corpo….andate su: https://amzn.to/2IZwjhm“Psichiatria Rock” - 50 pensieri off line dal mio blog….andate su: https://amzn.to/2IVKKmJBibliografia:Gómez-Eguílaz M, Ramón-Trapero JL, Pérez-Martínez L, Blanco JR. The beneficial effect of probiotics as a supplementary treatment in drug-resistant epilepsy: a pilot study. Benef Microbes. 2018;9:875-881.Liu J, Wan GB, Huang MS, et al. Probiotic therapy for treating behavioral and gastrointestinal symptoms in autism spectrum disorder: a systematic review of clinical trials. Curr Med Sci. 2019;39:173-184.Ng QX, Soh AY, Venkatanarayanan N, Ho CY, Lim DY, Yeo WS. A systematic review of the effect of probiotic supplementation on schizophrenia symptoms. Neuropsychobiology. 2019;78:1-6.Fusar-Poli L, Surace T, Vanella A, et al. The effect of adjunctive nutraceuticals in bipolar disorder: A systematic review of randomized placebo-controlled trials. J Affect Disord. 2019;252:334-349.Leblhuber F, Steiner K, Schuetz B, Fuchs D, Gostner JM. Probiotic supplementation in patients with Alzheimer's dementia—an explorative intervention study. Curr Alzheimer Res. 2018;15:1106-1113.Wang H, Lee IS, Braun C, Enck P. Effect of probiotics on central nervous system functions in animals and humans: a systematic review. J Neurogastroenterol Motil. 2016;22:589-605.Mayer EA. Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci. 2011;12:453-466.Kazemi A, Noorbala AA, Azam K, Eskandari MH, Djafarian K. Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: a randomized clinical trial. Clin Nutr. 2019;38:522-528.Gondalia S, Parkinson L, Stough C, Scholey A. Gut microbiota and bipolar disorder: a review of mechanisms and potential targets for adjunctive therapy. Psychopharmacology (Berl). 2019 Apr 30.Johnson KV, Foster KR. Why does the microbiome affect behaviour? Nat Rev Microbiol. 2018;16:647-655.Huang R, Wang K, Hu J. Effect of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials. Nutrients. 2016;8.

In this episode of BrainWaves, Dr. Joseph Berger discusses the complications of HIV literally from head to toe. From neuropathy to myelopathy to neurocognitive disorders as well as the myriad of opportunistic infections. Definitely worth your time. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision making in routine clinical practice. The content in this episode was vetted and approved by Joseph Berger for broadcast. REFERENCES 1. Ellis R, Langford D and Masliah E. HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci. 2007;8:33-44. 2. Boisse L, Gill MJ and Power C. HIV infection of the central nervous system: clinical features and neuropathogenesis. Neurol Clin. 2008;26:799-819, x. 3. Garg RK. HIV infection and seizures. Postgraduate medical journal. 1999;75:387-90. 4. Dore GJ, Law MG and Brew BJ. Prospective analysis of seizures occurring in human immunodeficiency virus type-1 infection. J NeuroAIDS. 1996;1:59-69. 5. Di Rocco A and Simpson DM. AIDS-associated vacuolar myelopathy. AIDS Patient Care STDS. 1998;12:457-61. 6. Murdoch DM, Venter WD, Van Rie A and Feldman C. Immune reconstitution inflammatory syndrome (IRIS): review of common infectious manifestations and treatment options. AIDS Res Ther. 2007;4:9.