Podcasts about Sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis --- ▼ Follow Arsen Movsisyan SoundCloud: https://soundcloud.com/arsen-movsisyan Facebook: https://www.facebook.com/arsenmovsisyan

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis --- ▼ Follow Arsen Movsisyan SoundCloud: https://soundcloud.com/arsen-movsisyan Facebook: https://www.facebook.com/arsenmovsisyan

Ep. 126 ⬇️ DOWNLOAD YOUR FREE ATTACHMENT STYLES THERAPY HANDOUT: https://mht.thrivecart.com/attachment-styles-quick-guide/   ▶️ WATCH THE INTERVIEW: 

If you've ever felt confused, second-guessed yourself in a relationship, or wondered if someone in your life is emotionally manipulating you, this episode is one you need to hear.More info, resources & ways to connect - https://www.tacosfallapart.com/podcast-live-show/podcast-guests/dr-stephanie-sarkisOn this episode of Even Tacos Fall Apart, I sat down with Dr. Stephanie Sarkis to talk about toxic relationships, gaslighting, and the real challenges of healing from emotional abuse. Stephanie is a licensed mental health counselor, a mediator, and an author of multiple books, including Gaslighting: Recognize Manipulative and Emotionally Abusive People—and Break Free. She's also a contributor to Forbes and Psychology Today, and she hosts her own podcast, Talking Brains. Basically, she knows her stuff.Stephanie shared how she was always the person friends came to for relationship advice, and after originally planning to work for CNN, she pivoted to counseling and never looked back. Her work, especially her books, are inspired by real-life experiences from her clients—many of whom struggle with gaslighting, ADHD, anxiety and depression. She said the feedback she gets from readers who've found the courage to leave toxic relationships is one of the most rewarding parts of her work.We talked a lot about gaslighting—what it is, how it works, and what it looks like. According to Stephanie, gaslighting is a form of emotional abuse designed to make you question your reality. It often starts small and escalates until you're isolated and unsure of your own thoughts. It can include things like hiding your stuff and blaming you for it, love-bombing you early on, then tearing you down, or pitting you against people close to you. She made it very clear: gaslighting is all about control.Stephanie also broke down the stages of gaslighting—idealization, devaluation and discard—and how those phases mess with your head. And if you're wondering whether narcissists are involved, the answer is yes—often. Especially the kind who never think they're the problem and rarely show up for therapy unless it's to blame someone else.We also talked about the trickiness of co-parenting with a gaslighter, especially if you can't go completely no-contact. Stephanie had practical advice for managing communication through apps like Our Family Wizard and Talking Parents, keeping interactions minimal and getting everything documented.When it comes to healing, Stephanie stressed the importance of therapy, support systems, and going completely no-contact if possible. She said that survivors often carry guilt and shame, especially when the abuser is a parent or partner. But it's okay to protect your peace. You don't owe anyone continued access to you—especially someone who's hurt you.The interview wasn't all heavy—we laughed about tone checkers for work emails, how pets can spot a toxic person before you can, and how important it is to find humor even when things are hard. Stephanie also shared her favorite poem (Richard Cory) and how it reminds her that we never really know what someone's going through.This conversation was real, honest and empowering—just what Mental Health Monday is all about.

Gaslighting is a technique of manipulating others to gain control. Gaslighters use a series of tactics to distort the truth making their victims question their own reality. Dr. Stephanie Sarkis sheds light on gaslighting and she offers strategies to help us cope and break free. Dr Sarkis is a psychotherapist specializing in ADHD, anxiety, and narcissistic abuse. She is a senior contributor to Forbes, and is also a contributor to Psychology Today and The Huffington Post. Dr. Sarkis is the best-selling author of multiple books including, Gaslighting: Recognize Manipulative and Emotionally Abusive People -- and Break Free.   Follow CYACYL: Website: www.cyacyl.com Digital: www.cyacyl.com/digital Upcoming shows: www.cyacyl.com/shows Facebook: www.facebook.com/changeyourattitudechangeyourlife Music: www.purple-planet.com

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

From Chummy Studios, Hye Jams Radio presents, “Paisan and Friends,” brought to you by Haig's Kabob House. Tonight on Paisan and Friends, your favorite New York Italian host, Paisan, introduces us to a woman who's one egg short of a dozen—but in the best way possible! Meet the legendary Qyarti Girl, an Armenian firecracker who came to America with nothing but her quirks, her wild fashion sense, and an unshakable love for life. Somehow, in the middle of all her glorious weirdness, she accidentally falls for the most normal guy in town—Sarkis. But as fate would have it, she drags him into her world of mismatched shoes, offbeat adventures, and spontaneous jam sessions. It's a tale of love, laughter, and just the right amount of crazy—a perfect match for Today's Hit Music and the incredible variety of jams we've got lined up.  Check out NEW Hye Jams by Harout Bedrossian, Parg and Aksa. Plus HITs you know and love from Rafael Tunyan, MC Don Armani, Amal'ka, Arkadi Dumikyan, Armstrong, Arajin Akumb, Harout Balyan, Sammy Flash, DJ Apo, Kolo, Hrag, Sash, Narek Face, Big E, Armenchik, MikS, Ninell, Karen TY3, Grigory Esayan, Aleksandr and Emmy -- to name a few. Tune in now and buckle up, because this one's going to be one heck of a ride on Hye Jams Radio!

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

▼ Follow Nicksher Music: » Spotify Playlist: https://open.spotify.com/playlist/4dI7kNNcEGQ8MSGLYVh39T?si=Zg1yjJAHTASjK7xa5S-Lew » SoundCloud: https://soundcloud.com/nickshermusic » YouTube: https://www.youtube.com/channel/UCcTF27v-cpxlBfLdQODpFTw » Facebook: https://www.facebook.com/groups/1706975586219784/ » Beatport: https://beatport.com/label/nicksher-music/57468 » VK: https://vk.com/club123650463 » Instagram: https://www.instagram.com/nickshermusic/ --- ▼ Follow Edo Sarkis: Soundcloud: https://soundcloud.com/edgar-sarkis VK: https://vk.com/edo.sarkis

Alevilere yönelik saldırıları değerlendiren gazeteci Sarkis Kassargian, "Suriye'deki grupları silah bırakmaya ikna etmek artık daha zor" dedi. Kassargian, bölgedeki son gelişmeleri yorumladı.

Fr Chris Sarkis says that Lent invites a radical transformation of heart that goes beyond simple conversion to embrace a new way of life, similar to the repentance shown by the people of Nineveh

Os índices de capital são essenciais para a solidez dos bancos, mas vão muito além de uma exigência regulatória. Como essas métricas impactam a estratégia, a precificação e a gestão de riscos no setor financeiro? No episódio de hoje, Marcelo Sarkis, Head de Risco no Banco Sofisa e Janny Castro - Diretora de Financial Services na Forvis Mazars, discutem as mudanças no Acordo de Basileia, os desafios da alocação de capital e os novos riscos que moldam o mercado, como cibersegurança e fatores climáticos.Participantes:Marcelo Sarkis, Head de Risco, Sofisa.Host(s):Janny Castro, Diretora de Financial Services, Forvis Mazars.Alexandre Abreu, Apresentador, Tracto.

JEAN FIXX. VIRTUAL BODY LANGUAGE.DULZARO. ICAROZABALA. NIRE AZALA (VERDE PRATO)DELAMESETA. RONDA DE OLOMBRADAFARFASH-SABO & SARKISPALOROTO. AGUJETA RIDDIM.MITA GAMI. WHAT IF IT´S ALL RIGHTONUR ÖZER. HALIKARNASPYE CORNER AUDIO. RESIST TALVIN SINGHT. BUTTERFLYEscuchar audio

Dr. Stephanie Sarkis, psychotherapist, American Mental Health Counselors Association Diplomate, and author of Gaslighting, shares the subtle (and not-so-subtle) signs that you're in a cycle of emotional abuse —from dysfunctional behaviors that have been normalized in media, feeling trapped in a job where you're being mistreated, and insidious romantic relationships.Full episode with Dr. Sarkis: https://www.selfhelplesspodcast.com/episodes/episode/2a31527c/the-psychological-impact-of-gaslighting-with-dr-stephanie-sarkisIf this, or past, episodes have helped you, you can support the podcast here: https://www.patreon.com/selfhelplessYour Host, Delanie Fischer: https://www.delaniefischer.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In episode 95, I sit down with Josh Sarkis, Chief Strategy Officer for PharmaSmart, to uncover the transformative world of healthcare technology and innovation. Recorded amidst the buzz of the Health Innovators Conference, our conversation takes a deep dive into Josh's inspiring journey from a small business owner to a key player in revolutionizing blood pressure monitoring. Josh recounts PharmaSmart's origins, starting as a distributor of blood pressure kiosks, and the pivotal decision to design their own clinically validated devices. We explore the evolution of their patented kiosks, which have set a new standard for accuracy, accessibility, and integration in healthcare. Key Insights: The groundbreaking design of PharmaSmart's blood pressure kiosks and their role in improving patient care. How automation in healthcare can enhance efficiency and free up healthcare professionals for critical tasks. The adaptability and innovative thinking needed to address challenges in blood pressure measurement. Discover How: PharmaSmart is revolutionizing vital sign monitoring in pharmacies, workplaces, hospitals, and clinics. Their kiosks empower patients through user-friendly tracking and seamless integration into electronic medical records. Entrepreneurs can overcome setbacks by staying adaptable, listening to customers, and focusing on long-term goals. Josh also shares his vision for the future of healthcare technology, discussing potential advancements like additional vital sign monitoring, mental health screening, and addressing social determinants of health. His dedication to creating accessible solutions for community care is both inspiring and actionable. "Success comes from persistence, staying close to your customers, and always being willing to adapt." – Josh Sarkis This episode is a must-listen for healthcare professionals, innovators, and entrepreneurs seeking inspiration at the intersection of technology and patient care. Tune in for an engaging conversation filled with insights into how technology is shaping the future of healthcare. Connect with PharmaSmart and Josh Sarkis: Visit their website: www.pharmasmart.com PharmaSmart LinkedIn Josh Sarks's LinkedIn

Fr Chris Sarkis says that in life's storms we can feel overwhelmed. Jesus assures us with his words, “Courage! It is I! Do not be afraid,” but more importantly, he enters our situation, walking with us and calming our fears. He never abandons us; instead, he fills our hearts with strength, hope, and peace, even carrying us when we feel too weak to move forward

Piezo touch and pressure-sensing ion channels are showing up everywhere as the explanation for physiologic phenomena, both at the macro and micro levels. Ardem Patapoutian, my friend and colleague at Scripps Research, discovered these receptors back in 2010 and was awarded the Nobel Prize in 2021 for his work. As you'll see/hear from our conversation, the field has exploded. And you'll get to know Ardem, who is such a fun, charismatic, and down-to-earth person. He also recently got a unique tattoo (videos below) and I wonder (unlikely) if any other Nobel laureates have one related to their discovery?!Below is a video clip from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The current one is here. If you like the YouTube format, please subscribe! The audios are also available on Apple and Spotify.Transcript with links to audioEric Topol (00:07):Well, hello. It's Eric Topol with Ground Truths, and I've really got a special guest today. The first time for the podcast, I've been able to interview a colleague and faculty at Scripps Research, Ardem Patapoutian, who just by the way happens to be the 2021 Nobel Laureate in Physiology or Medicine. So welcome, Ardem. It's so wonderful to have you.Ardem Patapoutian (00:30):Thanks so much, Eric. Looking forward to chatting with you.Eric Topol (00:34):Well, this has been interesting because although I've known you for several years, I didn't research you. I mean, I had to learn about more than I even do. And of course, one of the great sources of that is on the Nobel Prize website where you tell your whole story. It is quite a story and not to review all of it, but I wanted to go back just before you made the call to move to Los Angeles from Beirut, Lebanon and with the scare that you went through at that time, it seemed like that was just extraordinary that you had to live through that.Ardem Patapoutian (01:11):Yeah, so I am of Armenian origin, but I was born in Lebanon and born in 1967, so I was eight years old when the civil war started. So it's a kind of bizarre childhood in the sense that with all the bombs and fighting in Lebanon. So it was tough childhood to have, but it was never personal. It was bombs and such. And so, the event you're talking about is, I happened to be kidnapped while crossing East to West Beirut. They only held me for four or five hours at first asking me questions to see who I am, but I think they pretty soon figured out that I was not a dangerous guy and they ended up letting me go. But before that, that incident really had a huge impact on me so that by the time I got home, I literally said, I'm out of here. I'm going to find a way to leave the country. And so, that's what, very quickly within a few months I packed and came to United States.Eric Topol (02:19):And how did you pick LA to be your destination?Ardem Patapoutian (02:22):Being from the Armenian community, there's a lot of Armenians in Los Angeles. My cousins already had moved there. They also grew up in Lebanon. And my brother, who's a few years older than me, got admitted to USC graduate school in engineering. So he was going to be there. So it made a lot of sense.Eric Topol (02:44):Oh yeah.Ardem Patapoutian (02:45):Unlike him, I came with no school or job prospects because it happened so fast that I kind of just left. One year I was at American University of Beirut for one year, but then just left and came here. So worked for a year in various jobs and then started going back to school to UCLA.Eric Topol (03:07):Yeah, I saw how there was about a year where you were delivering pizzas and before you got into UCLA, and that must have been an interesting off year, if you will. Well, the story of course, just to fast forward, you did your baccalaureate at UCLA, your PhD at Caltech, postdoc at UCSF, and then you came to Scripps Research 24 years ago along with Pete Schultz, and it's been quite an amazing run that you've had. Now, before we get into PIEZO receptors, the background, maybe you could help me understand, the precursor work seems to be all related to the transient receptor potential (TRP) series, also ion channels. They were of course related to whether it was heat and temperature or somatosensory. How do these channels compare to the ones that you discovered years later?Background on these Ion ChannelsArdem Patapoutian (04:09):Yeah, so the somatosensory neurons that innervate your fingertips and everywhere else in your body, their main job is to sense temperature and pressure. And this is very different than any other neuron or any other cell. So when you touch a hot stove that's burning hot, you need to know about that immediately within milliseconds or something cold. So the opposite side of it is pressure sensing, and it also comes in light touch, which is pleasant or a hammer hitting your finger, which is unpleasant. But all of these have the same characteristic anyway, that is your body has learned at the molecular level to translate a physical stimulus such as temperature and pressure into an electrical signal that neurons use to communicate with each other. But this idea of how you translate physical stimuli into chemical or electrical signal has been a long open question because as you know, most of our cells communicate by chemicals, whether that's hormones or small molecules, we know how that works, receptor bind to ligand, confirmational change and you get a kinase activation and that's enough. But here, how do you sense pressure? How do you sense temperature? It was just, there wasn't much known about that. And that's why our earlier work on TRP channels, which were temperature sensors came before the pressure. And so, they're very related in that sense.Eric Topol (05:52):The structure of these, if you were to look at them, do they look pretty similar? What the TRP as you say, and what you did back in the 2010 Science paper, which we'll link to, of course the classic paper where you describe PIEZO1 and PIEZO2, but if you were to look at this structures, would they look pretty similar?Ardem Patapoutian (06:14):No, that's a good question. And they absolutely don't. That's why finding these receptors were so hard. So if you go back to other sensory receptors, vision rhodopsin G-protein coupled receptor (GPCRs), larger G-protein coupled receptor look the same. So for example, when it was identified by chemically, that smell also works through G-protein coupled receptor. Richard Axel and Linda Buck, who also won the Nobel Prize, found those receptors by homology to visual GPCRs. The ion channels other than the fact that they crossed the membrane a few times or more, they have nothing else in common. If you looked at their structure, you can't even immediately tell they're ion channels. So you couldn't find these by structural homology or sequence homology. So you had to do something else. And usually that means functional screens and et cetera.Eric Topol (07:09):Well, yeah, and I'm in touch with the screening. We'll get to that and how you dig these up and find them. But the somatosensory ones are really interesting because I don't think a lot of people realize that when you have wasabi or you have Listerine mouthwash and feel the burn and that these are all mediated through these channels, right?Ardem Patapoutian (07:35):Yeah. So there's this whole field of chemesthesis, which means senses in your mouth, for example, that are not explained by taste transduction and olfactory. And these are actually by the same somatosensory neurons that help you sense temperature and pressure. And some of these receptors are the same. Their evolution has taken over and used them for many different things. The prime example of this is the capsaicin receptor that David Julius my co-laureate identified, which is also heat receptors. So all languages describe chili peppers as hot, and that's not a coincidence. It actually activates heat activated channel, and that's why we think of it as hot. And so, the same goes to another one of these TRP channels that you mentioned, which is TRPA1, and this one is also activated, but a lot of spicy foods other than the chili pepper active ingredient includes what's in garlic and onions and everything that has this burning sensation and chemicals of this and wasabi and chemicals of this are used in over the counter products like Listerine that cause that burning sensation.Eric Topol (08:54):So when you're chopping onions and it makes you cry, is that all part of it as well?Ardem Patapoutian (08:59):That's all TRPA1, yeah.The Discovery, A Test of PerseveranceEric Topol (09:01):It's wild. Now, this was the groundwork. There were these heat temperature and somatic sensory, and then you were starting to wonder what about touch, what about out pressure and proprioception. And so, you went on a hunt, and it's actually kind of an incredible story about how you were able to find out of these cells that you had, screening hundreds or I guess you got to 72 different small interfering RNA blocking that you finally found the one. Is that right?Ardem Patapoutian (09:37):That's right. So in retrospect, looking back at it, I think there's such an interesting scientific message there. And so, many of us were looking for this touch pressure sensors and we were all looking in the DRG sensory neurons that are complicated heterogeneous, they don't divide. It's not easy to do a screen on them. And ultimately after a lot of failures, what worked for us is to take a step back and ask a much more simpler question. And that was, can we find one of these cell lines that you could easily homogeneously grow in a culture dish, if they respond to mechanical force, can we find our channel there? And then go back and look if it's relevant in vivo for what process. So I think the message is ask the simplest question to answer the question you're after. And finding what that is, is actually the challenge lots of times.Ardem Patapoutian (10:36):But yeah, that's what Bertrand Coste in my lab did is found a simple cell line that neuroscientists had been using for a hundred years and somehow found that they over overexpressed this channel because you can record from them, you can push them and record the currents from them. And then it became a simpler question of finding it. It still took a whole year. He made a list and one by one knocking them out and looking at it. And finally, as you say, number 72 was the hit. When he knocked that out, the current was gone. And that's where we started believing that we have what we were looking for.Eric Topol (11:12):Were you all ever about ready to give up at that point?Ardem Patapoutian (11:16):Oh yeah. I mean that's another lesson. These are postdocs doing the work, right? And they're here three, four years and this was coming close to end of two years, and he didn't have anything yet. So we started talking about having a backup project and he started that and we said, okay, we were ordering this oligos 30 at a time because they're expensive. And so, the first 30 nothing, the second 30 nothing. And how many more are we going to do before we potentially give up? And we said, well, let's do at least a third and then decide, thank goodness it was in that last set.Eric Topol (11:54):Wow, that is so wild. Now what's happened since this discovery, which I guess when you published it in 2010, so it means 14 years ago, but we're on this exponential growth of learning that these piezo receptors are everywhere. They're doing everything. In fact, I recently put on Bluesky, PIEZO ion channels are to human physiology as GLP-1 drugs are to treating many diseases because it's just blowing up. And you've published on some of these of course, on itch and bladder function and vascular function. We'll get to maybe malaria, I mean, but even the cover of Science recently was about wet dog shakes and how animals shake because of water. These receptors are so fundamental to our function. So maybe you could comment, 15 years ago when you were doing the work and you're making this discovery, did you ever envision it was going to blow up like this?Ardem Patapoutian (12:57):Not to this level, but I should have. I think that this idea, again, that most of cell communication is through chemicals is of course a lot of it is true.Ardem Patapoutian (13:12):But it would be ridiculous for evolution to ignore all the physical forces, the pressures that cells experience. And once they do, you would think you would put an instructive way of sensing this pressure signal and using it beneficially to the system or the cell. And so, when we used to talk about pressure sensing at the beginning, there were a couple of touch, pain, maybe proprioception, hearing are like the poster children of pressure sensing. But I think what these molecules, as you say is enabling us is finding out the much more wider role that pressure sensing is playing in physiology and in disease that no one had thought seriously about. And this is, I compare sometimes the finding the PIEZO molecules. You're going in a dark room, and you need to find a door to get into there. And PIEZO is kind of that finding the door once you get in, now you use that molecule now to find physiology instead of the opposite way around. So by pursuing PIEZO expression and function, we're finding all these new roles that they play in physiology and in disease that we didn't think about. And because they're so specialized to sense tension, membrane tension, they don't do anything else. So if you see them expressed somewhere or if you see a function for them, you can bet that they are playing a role in sensing pressure. A lot of biology has kind of come from this hypothesis.Eric Topol (15:00):Well, I mean it is so striking to see the pervasiveness, and I do want to go back just for a second because when you name them PIEZO, you named it after the Greek word. How did you come to that name?Ardem Patapoutian (15:13):So Bertrand and I were actually sitting on Google Translate and we were typing pressure and trying to see what it's like in Greek or in Latin or different languages. His native French and my Armenian and píesi in Greek is pressure. And of course, what's really cool is that the word that more people know about this is piezoelectric device.Eric Topol (15:41):Oh, right.Ardem Patapoutian (15:41):Actually, translates physical force into electricity and vice versa. And in a way, this is a little molecular machine that does the same thing, and he uses this piezoelectric device to actually push on the cell. That's his assay. So it all came together as a very appropriate name for this gene and protein.Call from the Nobel CommitteeEric Topol (16:04):Oh really, it's perfect. And you get to name it, even that's fun too, right? Now we're going to go to getting the call at 2:00 AM, but it didn't come to you because your phone from the Nobel Committee was on ‘do not disturb' and your 94-year-old father, Sarkis. How did the Nobel Committee know to get ahold of him? How did they reach him in the middle of the night?Ardem Patapoutian (16:37):Yeah, so I mean, since receiving it, I've had conversations with various committee members, and they are very resourceful folks, and they have assistants who throughout the year collect information on all potential people who might win. They're also doing last minute searches. So they looked for other Patapoutian's in California. So they just called my dad who initially yelled at them for disturbing him at 2:00 AM.Eric Topol (17:17):And he could get through to you because he was not on your list of ‘do not disturb' or something like that.Ardem Patapoutian (17:22):I didn't even know this. And I don't know if the policy has changed, but in some phones the ‘do not disturb' if it's called by someone who's in your contacts or favorites.Ardem Patapoutian (17:34):After I think they called twice and they get through, and that's how.Getting a Tattoo!Eric Topol (17:39):That's amazing. Wow. Well, that's quite a way to find out that you're getting recognized like this. Now recently you got a tattoo, which I thought was really remarkable, but we're going to put that of course in the post. Tell us about your decision to get the PIEZO channel on your arm.Ardem Patapoutian (18:02):So as you can tell, I'm obsessed about PIEZO and it's been good to me. And I had the idea a while ago, and my very wise wife, Nancy Hong, said that you might be going through midlife crisis. Why don't you wait a year? If you still believe in it, you should do it. And that's what I did. I waited a year, and I was like, I still want to do it. And I guess I could show it. Here it is.Eric Topol (18:32):Oh yeah, there it is. Oh wow.Ardem Patapoutian (18:33):What's cool is that I can pretty much flex to show the activation mechanism because the channel is like bent like this in the plasma membrane. When it's stretched, it opens and it actually flattens like this. So I feel like other than being a tattoo, this is both performance art and instructional device. When I'm giving talks without PowerPoint slides, I could give a demonstration how this ion channel works.[Below is from a presentation that Ardem recently gave, the Harvey Lecture, at Rockefeller University.]Eric Topol (19:04):It's wild. Now how did you find a tattoo artist that could, I mean, it's pretty intricate. I mean, that's not your typical tattoo.Ardem Patapoutian (19:14):Yeah, I put it up on social media that I was thinking of doing this, and many scientists are into tattoos, so I actually got so many recommendations. And one of them was a local here in San Diego, and she is very popular. I waited six months to get this, I was on a waiting list. The appointment was six months off when we made it. So she's very popular and she's very good.Eric Topol (19:45):Was it painful to get that done?Ardem Patapoutian (19:47):Well, that's actually really cool, right? Because PIEZO2 is involved in pain sensation, and I felt it while it was being tattooed on my arm. The whole day, I was there like six and a half hours.New Prospect for Pain MedicationEric Topol (20:00):Oh my gosh. Wow. Now that gets me to pain because, I'd like you to talk a bit about the people that don't have mutations or loss of function PIEZO receptors and also what your thoughts are in the future as to maybe we could develop a lot better pain medications.Ardem Patapoutian (20:22):Yeah, we're working on it. So you're right. One of the great parts of the science story, and this is mainly the work of Alex Chesler and Carsten Bönnemann at the NIH, where they identified people who came to the clinic for undiagnosed conditions, and they were uncoordinated and had difficulty walking. And when they did whole-exome sequencing, they found that they had mutations in PIEZO2, there were loss of function, as you say. So complete loss on both chromosomes. And when they started testing them, they realized that just like we had described them in animal models, humans without PIEZO2 as well, didn't sense touch, don't have proprioception. This sense of where your limbs are, that's so important for balance and most other daily functions that we take it for granted. So they were completely lacking all of those sensations. They also do not feel their bladder filling.Ardem Patapoutian (21:26):And so, they have learned to go on a schedule to make sure they don't have accidents. And many of these projects that we've done in the lab collaboration with Alex Chesler, et cetera, have come from the observations of what else these individuals experience. And so, it's been a great kind of collaboration communication between mechanistic animal model studies and the clinic. And so, one of the things that these individuals don't sense in addition to touch, is something called tactile allodynia, which is simply when touch becomes painful. You and I experienced this after small injury or sunburn where just touching your shoulder becomes painful, but for peripheral neuropathy and other neuropathic pain conditions, this is one of the major complaints that individuals have. And we know from the NIH studies that these individuals don't have this tactile allodynia. So touch becomes painful and doesn't apply to them, which tells us that if we block PIEZO2, we can actually get interesting relief from various aspects relative to neuropathic pain on other pain related neuropathies. But given everything we talked about, Eric, about how this is important for touch and proprioception, you don't want to make a pill that blocks PIEZO2 and you take it because this will have some serious on target side effects. But we are developing new compounds that block PIEZO2 and hope that it might be useful, at least as a topical medication pain and other indications. And we're actively working on this, as I said.Eric Topol (23:15):Yeah, I mean the topical one sounds like a winner because of peripheral neuropathy, but also I wonder if you could somehow target it to sick cells rather than if giving it in a systemic targeted way. I mean it has tremendous potential because we are on a serious hunt for much better relief of pain than exists today.Ardem Patapoutian (23:41):Absolutely.Eric Topol (23:42):Yeah. So that's exciting. I mean, that's another potential outgrowth of all this. Just going back, I mean the one that prompted me in November to write that about the human physiology in PIEZO, it was about intestinal stem cell fate decision and maintenance. I mean, it's just everywhere. But the work you've done certainly now has spurred on so many other groups to go after these different and many unanticipated functions. Were there any ones, of course, you've been pretty systematically addressing these that actually surprised you? You said, oh, are you kidding me when you read this? I never would've guessed this, or pretty much they followed suit as things were moving along.Ardem Patapoutian (24:33):So one of them is this role in macrophages that I found fascinating that we found a few years ago. So again, this came from human studies where PIEZO1 gain-of-function mutations. So in relation to loss of function, their gain-of-function where there's more activity given a certain amount of pressure. They have dehydrated red blood cells, which I'm not going to talk about right now. But they also have shown that in these patients, individuals, it's not really that pathological. They also have age-onset iron overload. What does that have to do with pressure sensing? And we brought that information into animal models, and we found that macrophages, their rate of phagocytosis depends on PIEZO, so that if you have too little PIEZO, they don't phagocytosis as much. If you have too much PIEZO, the phagocytosis too much. And this increased rate of phagocytosis in the long term because it's constantly eating red blood cells and the iron is circulating more causes long-term effects in iron overload. And again, as you kind of set that up, who would've thought that mechanical sensation is important for this basic hematology type?Eric Topol (25:52):Yeah, I mean, because we've been talking about the macro things, and here it is at the cellular level. I mean, it's just wild.Ardem Patapoutian (25:59):If you go back and look at a video of a macrophage eating up red blood cells, then you go, oh, I see how this has to do with pressure sensing because it is like extending little arms, feeling things letting go, going somewhere else. So again, I want to bring it back by this simple cell biological function of a cell type, like macrophage, exploring its environment is not just chemical, but very mechanical as well. And so, in retrospect, it is maybe not that surprising, that pressure sensing is important for its physiology.Career Changing?Eric Topol (26:33):Yeah, that's extraordinary. Well, that gets me to how your life has changed since 2021, because obviously this a big effect, big impact sort of thing. And I know that you're the first Armenian, first person from Lebanon to get this recognition. You recognized by the Lebanese Order of Merit. There's even a stamp of you, your picture characterized in 2022.Eric Topol (27:04):So if you were to sum up how it's changed because I see no change in you. You're the same person that has a great sense of humor. Often the tries to humor relaxed, calming. You haven't changed any to me, but how has it affected you?Ardem Patapoutian (27:26):Thank you, Eric. That's very kind of you. I try very hard for it not to change me. I do get a little bit more attention, a ton more invites, which unfortunately I have to say no to a lot of them because, and I'm sure you're very familiar with that concept and a lot of things are offered to you that I feel like it's so tempting to say yes because they're wonderful opportunities and an honor to be asked. But the end of the day, I'm trying to be very disciplined and not taking things on that I can do as an opportunity. But things that I really want to do. I think that's so hard to do sometimes is to separate those two. Why am I doing this? Is this really important for the goals that I have? So in one way, the answer for that is that I just want to stay in the lab and do my research with my students and postdoc, which is what I enjoy the most. But on the other hand, as you said, being the first Armenian who's received this, literally after the Nobel, I got this whole elementary school, all Armenian kids write to me multiple letters.Ardem Patapoutian (28:39):And they said, you look like me. I didn't think I could do this, but maybe I can. So in a sense, to ignore that and say, no, I just want to do my science, I don't want to be involved in any of that is also wrong. So I'm trying to balance being engaged in science outreach and helping to make science understood by the general public, realize that we're just regular people and at the same time how awesome science is. I love science and I like to project that, but leave plenty of time for me to just be a scientist and be in my lab and interact with my colleagues at Scripps, including you.Immigrant ScientistsEric Topol (29:21):Well, we're so lucky to have that chance. And I do want to mention, because you're prototyping in this regard about great immigrant scientists and other domains of course, but every year the Carnegie Foundation names these great immigrants and one year you were of course recognized. And in recent years, there have been more difficulties in people wanting to come to the US to get into science, and they wind up going to other places. It seems like that's a big loss for us. I mean, what if we weren't able to have had you come and so many hundreds, thousands of others that have contributed to this life science community? Maybe you could comment about that.Ardem Patapoutian (30:10):Yeah, I think it is tragic, as you say. I think in some circles, immigrants have this negative image or idea of what they bring, but at every level, immigrants have contributed so much to this country. It's a country of immigrants, of course, to start with. And I think it is important to put up a positive image of immigration and science is the ultimate example of that, right? I mean, I think when you go into any laboratory, you probably find if there's a lab of 16 people, you probably find people from 10 different countries. And we all work together. And the idea of also immigrant and especially about science is that I'm a big believer of changing field, changing things because just like that, immigrants have changed their whole life. So they come to a new culture, they bring with them their own way of thinking and their way of seeing things. And then you come into a new environment, and you see it a little bit differently. So that kind of change, whether it's because of physical immigration or immigrating from one field to another in science is really beneficial for science and society. And I think positive examples of this are an important part of highlighting this.Eric Topol (31:40):I couldn't agree with you more really.Bluesky vs Twitter/XEric Topol (31:41):Now, speaking of migration, there's been recently a big migration out of X, formerly Twitter to Bluesky, which I like the metaphor you liken to the Serengeti. Can you tell us about, now I know you're posting on Bluesky and of course so many others that you and I are mutual contacts, and our different networks are. What do you think about this migration outside of what was the platform where a lot of this, we shared things on X or before Musk took over known as Twitter? Thoughts about Bluesky?Ardem Patapoutian (32:27):Yeah, I think I use social media for a few reasons. The number one reason should be is to see new science by colleagues. My main point is that, but also, again, having fun in science is a big part of my draw to this. And as you can see from my posts, it's a bit lighthearted, and that's really me.Eric Topol (32:52):Right. Yeah.Ardem Patapoutian (32:52):I think on Twitter, things start getting a little bit dark and too many negative comments, and it was just not productive. And I just felt like after the elections, I felt like it was time to migrate. And I find Bluesky a great scientific community, and it's remarkable how quickly people have migrated from Twitter to Bluesky. But the counter argument for this is that you should stay in a place where majority of people are, because being in a bubble surrounding yourself by people like you doesn't help society. And so, I get that perspective as well. It just depends on what you're using the platform for and it's a difficult issue. But yeah, I've taken a break probably long-term break from Twitter. I'm on Bluesky now.Eric Topol (33:48):Yeah, no, the point you're bringing up about the echo chamber and is there going to be one for people that are leaning one way and they're thinking, and another with a whole different, often politically charged and even extreme views? It's really unfortunate if it does wind up that way. But right now, it seems like that migration is ongoing and it's substantial. And I guess we'll see how it settles out. I share your concern, and so far, I've been trying to keep a foot in both areas because I think if we all were to leave, then we're just kind of caving into a, it's tricky though. It really is because the noxious toxic type of comments, even when you try to avoid comments, you say, only followers can make a comment, they'll of course, quote your thing and then try to ding you and whatever. It's just crazy stuff, really.Ardem Patapoutian (34:53):I mean, what I think is that, that's why I said depends on why. I mean, your presence on social media is such an important part of science education. And I could almost say you can't afford to do what I do, which is I'm just putting my goofy posts and having fun. So we have different purposes in a way, and yeah, that affects what you use and how you use it.Eric Topol (35:17):Yeah, no, it's tricky it really is. We covered a lot of ground. Is there anything I missed that you want to get out there? Any part of this, your story and the PIEZO story, science and everything else that I didn't bring up?The Essentiality of Basic ScienceArdem Patapoutian (35:42):I just think that the basic science community is really suffering from decreasing amounts of funding and appreciation of doing basic science. And one of my goals, in addition to this immigrant scientist thing, is to remind people that all medicines start with basic science work. And funding this has mainly been through NIH and it's getting harder and harder for basic scientists to secure funding and I'm really worried about this. And we need to find ways to be okay for people to do basic science. And I'll give you one example. Whenever we make a publication and there's a journalist talking to us or some kind of press coverage, they ask, how is this directly affecting patients? And my work actually is very much related to patients, and I answer that question, but I also say, but it's also important to do science for the science sake because you don't know where the applications are going to come from. And we need to, as a society, encourage and fund and support basic science as the seeds of all these translational work. And I think doing that just kind of highlights that this is important too. We should support it, not just things that right now seem very related to translational that directly helps patients.Eric Topol (37:16):Well, I'm so glad you emphasized that because I mean, the PIEZO story is the exemplar. Look what's come of it, what might still come of it. In many respects here you are maybe 15 years into the story and there's still many parts of this that are untold, but if it wasn't for the basic science, we wouldn't have these remarkable and diverse insights. And recently you cited, and I think so many people read about the ‘crown jewel' NIH, front page New York Times, and how it's under threat because the new NIH director doesn't have a regard for basic science. He's actually, he's confirmed, which is likely, he's an economist, physician economist, never practiced medicine, but he doesn't really have a lot of regard for basic science. But as you point out, almost every drug that we have today came out of NIH basic work. And I mean, not just that, but all the disease insights and treatments and so much.Eric Topol (38:25):So this is really unfortunate if we have not just an NIH and other supporting foundations that don't see the priority, the fundamental aspect of basic science to then lead to, as we call translational, and then ultimately the way to promote human health, which is I think what we're all very much focused on ultimately. But you can't do it without getting to first base, and that's what you have done. You served it up and it's a great example. Well, Ardem, it's always a pleasure. This is a first time talking through a podcast. I hope we'll have many, many visits informally that will complement the ones we've already had, and we will follow the PIEZO work. Obviously, you have had just an exceptional impact, but you're still young and who knows what's next, right? I mean, look what happened to Barry Sharpless. He won here. He won two Nobel prizes, so you never know where things are headed.Ardem Patapoutian (39:36):Thank you, Eric, and I really appreciate what you do for the biomedical community. I think it's wonderful through your social media and this podcast, we all appreciate it.***********************************************************************************Please take a moment to complete the poll above.Thank you for reading, listening and subscribing to Ground Truths.If you found this informative please share it!All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and of course appreciated. All proceeds from them go to support Scripps Research. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. I welcome all comments from paid subscribers and will do my best to respond to each of them and any questions.Thanks to my producer Jessica Nguyen and to Sinjun Balabanoff for audio and video support at Scripps Research.And Happy New Year! Get full access to Ground Truths at erictopol.substack.com/subscribe

In this episode of Woo AgencyChat, Robbie and Robert interview Sarkis from ITQ Commerce, discussing agency challenges, client maturity, WooCommerce perceptions, AI effects, and the importance of community involvement.

In this episode of Woo AgencyChat, Robbie and Robert interview Sarkis from ITQ Commerce, discussing agency challenges, client maturity, WooCommerce perceptions, AI effects, and the importance of community involvement.

Fr Chris Sarkis says Advent is a time of waiting and spiritual preparation, reminding us that God's timing is different from ours, as He works beyond the constraints of time

#herkesesanat #çağdaşsanat Bir pisuar sanat tarihini nasıl değiştirdi? Öncüsü Beuys'a göre her insan bir sanatçı! Yüksek ve alçak kültür arasındaki sınırı bulanıklaştıran sanat biçimi! Anlamak çok zor! ... Bilgi Üniversitesi'nden Esra Yıldız rehberliğinde çağdaş sanatla tanışıyoruz. Çağdaş sanatın ne olduğunu, önemli sanatçı ve eserleri öğreniyoruz. ... Çağdaş sanat, yüksek kültürle alçak kültür arasındaki sınırı bulanıklaştıran, salt estetikten uzak, toplumsal kaygılarla üretilen sanat biçimi. Öncülerinden Joseph Beuys'a göre, her insan bir sanatçı. Belki bu yüzden çağdaş sanatı anlamak zor! Tarihsel aralık açısından sanat tarihçileri iki döneme işaret ediyor: İlki, 2. Dünya Savaşı sonrası dönem. Milyonlarca insanın toplama kamplarında öldürülmesi ve bundan sonra artık nasıl devam edileceği sorusu. Frankfurt Okulu'nun temsilcisi Adorno'nun, “Auschwitz'ten sonra şiir yazılamaz” sözünün ardından sanatçıların yapıtlarına dikkat çekti. İkinci dönem, 1960'dan günümüze kadar devam eden dönem. Feminizm, çevre hareketlerinin yükselişi, siyah haklar hareketi, 1968'de gençlerin ve işçilerin hareketi açısından önemli dönem. Sanatçıların bunlara karşılık gelen üretimlerini görüyoruz... ... Esra Yıldız'ın çağdaş sanata örnek olarak anlattığı sanatçılar ve eserleri: “Hazır yapıt” terimini literatüre kazandıran Fransız sanatçı Marcel Duchamp - 1917'de Bağımsız Sanatçılar Sergisi'ne gönderdiği ancak reddedilen eseri “çeşme / pisuvar”, modern sanat döneminde olsa bile, çağdaş sanatın kırılma noktası kabul ediliyor. Çağdaş sanatta önemli bir yeri olan, toplumu sanat aracılığıyla şekillendirmede önemli rolü olan Alman sanatçı Joseph Beuys. Ona göre her insan bir sanatçı. Almanya'da 2. Dünya Savaşı'nda tahrip edilen ve ekolojik yapısı bozulan Kassel kentini canlandırma amacıyla yaptığı “7 bin meşe” çalışması, örnek eserlerden. Bu bölüm için seçtiği müzikler: John Cage'ten “Music for Marcel Duchamp” ve “Fontana Mix” Joseph Beuys - Sonne statt Reagan 1982 Türkiye'den örnek verdiği sanatçılar: Ayşe Erkmen - Berlin'de bir evin dış cephesindeki “mış'lı” yerleştirmesi. İstanbul'da İstiklal Caddesi'nin Tünel tarafındaki bir heykeli var. Nur Koçak, Nil Yalter ve Sarkis'in de 70'lerden itibaren öncü isimler. Filmlerin, çağdaş sanatı anlamak açısından önemini vurguladı. Agnes Varda'nın “Les Glaneurs et la glaneuse” / “Toplayıcılar ve Ben” adlı belgeselinin izlenmesini önerdi, neden önemli olduğunu anlattı. Çağdaş sanat ve felsefe ilişkisine dikkat çekti, Fransız felsefeci Jean Francois Lyotard'ın 1985'te Paris Pompidou Kültür Merkezi'ndeki sergisinin önemli olduğunu belirtti. Bu sergi için: https://www.centrepompidou.fr/en/collection/film-and-new-media/les-immateriaux-1985 Ve günümüz filozoflarından Fransız sanatçı Georges Didi-Huberman'ın halen Madrid'de devam eden sergisini işaret etti. Bu sergiyle ilgili için: https://www.museoreinasofia.es/en/exhibitions/in-the-troubled-air NEDEN ESRA YILDIZ? İstanbul Bilgi Üniversitesi Kültür ve Sanat Yönetimi Bölümünde öğretim üyesi. Lisans derecesini Çevre Mühendisliği (İstanbul Teknik Üniversitesi, İTÜ) ve Sosyoloji (İÜ), yüksek lisans (İTÜ) ve doktora derecelerini (İTÜ) Sanat Tarihi bölümünden aldı. Doktora çalışmaları sırasında Technische Universität Berlin'de bulundu. Doktora sonrası çalışmalarını Berlin Humboldt Üniversitesi ve Paris EHESS'te sürdürdü. Critical Arts, African Arts, International Journal of Arts Management gibi dergilerde, Routledge, Intellect, İstanbul Bilgi Üniversitesi Yayınları gibi yayınevlerinden çıkan kitaplarda akademik çalışmaları, makaleleri yayınlanıyor. Akademik çalışmalarının yanı sıra, Sayfalar Arasında Bir Gölge: Sahaf Vahan (2010) ve Vatansız (2021) belgesel filmlerinin yönetmeni.

Participe do Evento Seleção 10x: https://lvnt.app/z986ol 05/12 - Bolsa 1,4%, Dólar R$ 6,01, ELET3 +4% e CVC3 -9% Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde, hoje é 5ª. feira, 5 de dezembro, e o programa é dedicado ao Valcir, Jader, Ricardo, Sarkis, Robson, Marcio, PortoBeloSC, Daniel, Rose e Carlos. Se vc não assistiu, assista e comente. O Ibovespa fechou em boa alta de +1,4% aos 127,8 mil pontos, com volume razoável de R$ 23,5 bi, R$ 1,5 bi abaixo da média de R$ 25 bilhões das quintas de mercado em alta. Por que a Bolsa performou assim? 1º. O Ibovespa à vista abriu em alta forte de quase 1,5 mil pontos indo de 126 mil para 127,5 mil pontos e ficou o dia inteiro oscilando entre esse último valor e 128 mil para fechar em 127,8 mil pontos. O principal motivo foi a Câmara dos Deputados ter aprovado ontem à noite o regime de urgência para o projeto de parte do pacote fiscal do Governo, Isso animou parte do mercado que saiu vendendo dólares – que caiu de R$ 6,05 para R$ 6,00 – fazendo juros futuros recuarem um pouco e, assim, a bolsa subiu. Nas ações, os destaques de alta na B3 foram, principalmente, ações que vinham caindo como: AZUL4 4%, ELET3 3,8% (Eletrobras (ELET3), que teve uma alta robusta de 4,02% após afirmar que não está mais discutindo com o governo federal uma antecipação de recursos devidos pela empresa para a Conta de Desenvolvimento Energético (CDE). Analistas projetam que esse acerto abre caminho para dividendos), VAMO3 3,5%, MULT3 3%, CYRE3 2,6%, VIVA 2,6% e SBSP3 2,2%. Já nas baixas, os destaques foram: CVCB3 -9%, YDUQ3 -1,2%, NTCO3 -0,80%, HAPV3 -0,70%e BRKM5 -0,60%. 2º. Na B3, 15 ações subiram entre as 15 ações mais negociadas com destaques para: VALE3 0,60% R$ 57,67, PETR4 1,3% R$ 39,77, ITUB4 2% R$ 33,35, SUZB3 0,10% R$ 65,10, ABEV3 3,1% R$ 14,37, BBAS3 1% R$ 25,54 e BBDC4 1,9% R$ 12,57, 3º. Já nenhuma ação caiu caíram entre as 15 mais negociadas que é um fato raro; 4º. O preço do petróleo recuou -0,20% para US$ 72,20 por barril, dentro do limite da volatilidade diária de -/+2%, com a decepção de investidores e traders com a reunião da Opep+ que caminha para não reduzir a produção dos países do cartel e com isso permanece a situação de leve produção acima da demanda fazendo o preço do petróleo Brent ficar entre US$ 71-74 e o WTI entre US$ 67-69,5. No Brasil, o preço da gasolina estaria abaixo da paridade em apenas -5% e do diesel -7% fazendo com que a Petrobras não necessite reajustar seus respectivos preços no curto prazo. A cia. reajustaria de a gasolina estivesse em -15% a -20% e diesel também. 5º. O minério de ferro caiu -1,7% para US$ 110,2 de US$ 112 a tonelada, ontem, dentro do limite da volatilidade diária de -/+2%, e sem novidades, e sem novidades. 6º. As bolsas americanas caíram, -0,55% Dow, -0,19% SP500 e Nasdaq -0,18%, em dia de realização de lucros em função do receio de que a geração de empregos tenha sido alta em novembro já que o número sairá amanhã às 9h30. 7º. O dólar recuou 4 centavos de R$ 6,05 para R$ 6,01, baixa de -0,60%, seguindo a queda de -0,58% do dólar norte-americano versus moedas fortes (DXY) em dia de realização de lucros depois de um semana de sucessivas altas. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou positivo em R$ 324 milhões na terça-feira, 3 de dezembro, conforme dados da B3. Com esse resultado, o saldo acumulado nos dois primeiros dias úteis de dezembro está positivo em R$ 584 milhões. No ano, os estrangeiros tiraram da Bovespa R$ 25,3 bilhões. MAIORES ALTAS ELET3 +4.02% R$ 36,46 IGTI11 +3.97% R$ 19,11 AZUL4 +3.73% R$ 4,73 ABEV3 +3.52% R$ 14,42 TOTS3 +3.50% R$ 28,06 MAIORES BAIXAS CVCB3 -8.98% R$ 2,33 HAPV3 -1.15% R$ 2,59 BRKM5 -1.11% R$ 15,21 YDUQ3 -1.00% R$ 8,91 NTCO3 -0.70% R$ 14,21

Confira nossas condições especiais da nossa Black Friday aqui: https://lvnt.app/ud2tyt 25/11: Bolsa estável, Dólar R$ 5,80, AZUL +9% e WEGE3 -3% Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde e Ricardo, hoje é 2ª. feira, 25 de novembro, e o programa é dedicado ao Dr. Nelson (faz 4 anos conosco e investiu em criptomoedas lá atrás), Marco Antônio (novo cliente e que veio desse Fechamento) e Filipe (desde 2022 conosco e é de SC, mas mora e trabalha no PR) todos clientes Sala VIP que tiveram reuniões de 1 hora cada conosco mais o Paulo William, Nicoletti, Francisco, Marco, Jean, Araújo, André, Sarkis, Solano e Abi Faiçal que escreveram elogiando o MM de Itaú x BB e se vc não assistiu vá lá e veja q vale muito. O Ibovespa fechou estável perto dos 129.268 pontos com volume bom de R$ 20 bi, na média de R$ 20 bi das segundas de mercado em alta. Por que a Bolsa performou assim? 1º. O Ibovespa trabalhou no campo negativo antes das 10h, quando abriu o mercado à vista, que foi para o positivo atingindo 129,5 mil pontos, às 10h25, para negativar às 10h40 e ficar oscilando entre o negativo e positivo até subir um pouco mais forte depois das 16h50 e fechar positivo. O principal motivo do negativo e positivo do índice, oscilando bem, foi as notícias da reunião de Lula e Haddad para definir os ajustes finais no pacote de corte de gastos do governo e, conforme, algumas supostas decisões eram publicadas afetava os mercados tanto de ações como dólar e juros. Porém, apenas depois doa divulgação do pacote, provavelmente, amanhã é que teremos as primeiras reações as decisões tomadas. Na B3, as ações de BB (último dia para ganhar JCP de quase R$ 0,50), Vale (minério), Eletrobras e B3 lideraram as altas enquanto bancos foram mistos e Petrobras perto da estabilidade depois de subir 5% na sexta-feira por conta dos potenciais dividendos com o novo plano estratégico da cia. a ser divulgado. No lado negativo, cederam ações de exportadoras como Weg, Suzano e Embraer apesar do dólar ficar quase estável. 2º. Na B3, 8 ações subiram entre as 15 ações mais negociadas com destaques para: BBAS3 0,4% R$ 25,70, ELET3 1,5% R$ 35,89, VALE3 0,5% R$ 58,46, B3SA3 1% R$ 10,12 e ITUB4 0,1% R$ 34,11. 3º. Já 7 ações caíram entre as mais negociadas com destaques para: PETR4 -0,15% R$ 39,37, WEGE3 -2,7% R$ 52,54, SUZB3 -1% R$ 60,06, BBDC4 -0,90% R$ 13,68. 4º. O preço do petróleo caiu -2,5% para US$ 73,1 versus US$ 74,3, sexta-feira, um pouco acima do limite da volatilidade diária de -/+2%, com notícias de que Israel e Líbano teriam acordado alguns pontos para terminar o conflito ente Israel e Hezbollah. 5º. O minério de ferro subiu 0,90% a US$ 107,9 de US$ 106,9, sexta, dentro do limite da volatilidade diária de -/+2%, e sem novidades. 6º. As bolsas americanas subiram, 0,3% Nasdaq e 1% Dow, com a escolha de Trump para o cargo de Secretário do Tesouro – equivalente ao de ministro da Fazenda no Brasil – de Scott Bessent, fundador do Key Square, um hedge fund americano, porque ele é considerado um conservador fiscal, o que reduzia temores dos investidores com o aumento do déficit da maior economia do mundo levando a juros maiores e dólar mais alto. Assim, hoje os juros dos títulos de 10-anos caíram bem, de 4,40% para 4,26% a.a., o dólar caiu -0,60% frente moedas contribuindo para as bolsas avançarem. 7º. O dólar cedeu 1 centavo para R$ 5,80 de R$ 5,81, seguindo, com investidores brasileiros precificando as incertezas do pacote de cortes de gastos e não a indicação do secretário do Tesouro quando Trump assumir. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou negativo em R$ 312 milhões na quinta-feira, 21 de novembro, segundo informações da B3. Com esse resultado, o saldo acumulado em novembro pelos estrangeiros no mercado secundário da bolsa brasileira está negativo em R$ 2,0 bilhões.

Conheça o método SGR através do grupo exclusivo: https://lvnt.app/evowa8 28/10: Bolsa +1%, AZUL4 +14% e HYPE3 -8% Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde e Ricardo Afonso, e hoje é 2ª. feira, dia 28 de outubro, e o programa de hoje é ao Nicoletti, Sarkis, Gílson, Eliseu de Santa Teresa RJ, Robson, Fabíola, Giovanini, Costa e Careca Russo (Brava?) O Ibovespa fechou em alta de +1%, aos 131.212 pontos, com volume fraco de R$ 17 bi, R$ 8 bi abaixo da média de R$ 25 bi das sextas. Por que a Bolsa performou assim? 1º. A bolsa abriu em alta e subiu o dia inteiro com leve recuos e voltando sempre para cima fechando com alta de +1% aos 131.212 pontos. A alta do Ibovespa foi causada pela combinação de petróleo despencado -5% a US$ 72 em função dos mísseis de Israel terem atingido apenas alguns alvos militares diminuindo sensivelmente o risco de escalada da guerra no Oriente médio, mais a subida de +2,3% do minério de ferro na China para US$ 110 por tonelada, mais a estabilidade do dólar e leve queda dos juros futuros que fez ações de bancos subirem lideradas pela Bradesco que divulgará resultados na quinta, mais alta de ações de cias. de carnes. 2º. Na B3, apesar do volume fraco e sem nenhuma ação ter alcançado R$ 1 bilhão de volume financeiro, 11 ações subiram entre as 15 ações mais negociadas com destaques para: AZUL4 14% R$ 6,11% em função de acordos com seus atuais detentores de títulos de dívida da cia. que possibilitará até US$ 500 milhões (R$ 2,850 bilhões ao câmbio de R$ 5,70); VALE3 1,8% R$ 62,88 por conta da alta de 2,3% do minério mais o bom momento pós-acordo de indenização das vítimas – pessoas físicas até governos - sobre desastre de Mariana (Samarco, VALE + BHP); SUZB3 0,70% R$ 59,37 ainda refletindo os resultados recordes da cia. no 3T24; ITUB4 1,5% R$ 35,84 com expectativa positiva de resultados, a serem divulgados dia 4/11, com lucro líquido recorde em torno de R$ 11 bi; e BBDC4 1,8% R$ 15,20 que divulgará dia 31/10, 5a. feira, antes das 10h, com projeções de lucro entre R$ 5,0 bi e R$ 5,2 bi. 3º. Apenas 5 ações caíram entre as mais negociadas com destaques para: PETR4 -0,20% R$ 36,09 em função da queda do preço do petróleo, BBAS3 -0,20% R$ 26,32, PRIO3 -1,7% R$ 40,95 e HYPE3 -8,7% R$ 23,92. 4º. O preço do petróleo despencou -5%, a US$ 72 de US$ 75,9, sexta, muita acima do limite da volatilidade diária de -/+2%, com investidores acreditando que a guerra no Oriente Médio pode não aumentar e, portanto, parte do sobrepreço do petróleo teria sido tirado hoje. 5º. O minério de ferro apresentou alta de 2,3% para US$ 110,0 de US$ 108,1 por tonelada, sexta, com parte de investidores acreditando que recentes medidas de estímulos monetários pelo governo chinês surtirão efeitos na economia e na procura por aço que demandará mais minério. 6º. As bolsas americanas subiram, 0,30% o Nasdaq e 0,65% o Dow, com investidores de novo comprando ações das big techs que divulgarão resultados nessa semana: Alphabet/ Google (terça), Meta/Facebook e Microsoft (quarta), e Apple e Amazon (quinta). O Dow subiu liderado pela Dow, 4%, Goldman, 2%, JPMorgan, 1.4% e McDonald´s, 1,4% 7º. O dólar à vista ficou estável a R$ 5,70, seguindo o dólar no exterior. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou negativo em R$ 45 milhões na quinta-feira, 24 de outubro, conforme dados da B3. No mês de outubro, o saldo acumulado pelos estrangeiros está negativo em R$ 3,1 bilhões. No ano, os estrangeiros tiraram da Bovespa R$ 23,4 bilhões. Os estrangeiros respondem por 58,30% do volume negociado em outubro e por 55,20% do volume no ano. MAIORES ALTAS AZUL4 +13.99% R$ 6,11 IRBR3 +6.80% R$ 44,16 BRFS3 +4.71% R$ 25,56 UGPA3 +4.48% R$ 21,00 JBSS3 +4.07% R$ 36,03 MAIORES BAIXAS HYPE3 -8.70% R$ 23,92 PRIO3 -1.68% R$ 40,95 BRAV3 -1.35% R$ 16,80 EMBR3 -1.25% R$ 48,94 PCAR3 -0.95% R$ 3,14

Conheça o método SGR através do grupo exclusivo: https://lvnt.app/evowa8 25/10 - Bolsa -0,13%, VALE3 +4% a R$ 61,88 Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde e Ricardo Afonso, e hoje é 6ª. feira, Graças a Deus, dia 25 de outubro, e o programa de hoje é ao Marcelo (Victor FIIs mandou bem), Sarkis (Ótimo fechamento com FIIs), Sergio Santos (FIIs caem com juros em alta de LP), Orimo (FIIs é sexta, mas teve q mudar essa semana) e Sandro (TRBL11 imóvel interditado). Hoje é sexta, dia de indicar séries e filmes e a de hoje é “Monstros: Irmãos Menendez: Assassinos dos Pais” na Netflix. Esta série é sobre um crime real examina as vidas dos irmãos Menendez, condenados pelo assassinato brutal dos pais em 1989. Eu estou quase no fim e o Ricardo que me indicou. O Ibovespa fechou em leve baixa de -0,13%, aos 129.893 pontos, com volume melhorou para R$ 20 bi, R$ 5 bi abaixo da média de R$ 25 bi das sextas. Por que a Bolsa performou assim? 1º. A bolsa abriu em alta e foi a 130,5 mil pontos, às 11h56, mas os vendidos em Ibovespa, como fundos multimercados que não entendem de bolsa e acham que o mercado se resume ao binômio inflação e juros, entraram vendendo Ibovespa, mas com não conseguiam negativar Vale e Petrobras saindo vendendo bancos – sem motivo para cair – B3, Renner, Hapvida e Localiza. Aí, o índice negativou e passou a tarde assim até fechar com -0,13%. Dessa forma, os vendidos não terão ajustes negativos, ou seja, porem dinheiro, nas respectivas contas. Essas “inovações” de ibovespa futuro e posições vendidas só prejudicam investidores de ações. 2º. Na B3, somente 5 ações subiram entre as 15 ações mais negociadas com destaques para: VALE3 3,4% R$ 61,73 por conta da combinação de resultados acima do esperado e acordo sobre desastre de Mariana (Samarco, VALE + BHP). PETR4 0,70% R$ 36,15 com petróleo subindo 2% hoje, Suzano 3% R$ 59,15 com resultados sólidos e muito acima do ano passado, RAIL3 0,70% R$ 19,22 e PETR3 1% R$ 39,40. 3º. Já 10 ações caíram entre as mais negociadas com destaques para: ITUB4 1,2% r$ 35,28, HYPE3 -5,5% R$ 26,20, BBDC4 -1,4% R$ 14,94, B3SA3 -1% R$ 10,68, e LREN3 -1,9% R$ 18,48. 4º. O preço do petróleo subiu 2%, a US$ 75,9 de US$ 74,7, ontem, dentro do limite da volatilidade diária de -/+2%, com parte de investidores acreditando que os fundamentos de demanda não são tão fracos como veem sendo precificado. A ver. 5º. O minério de ferro alta de 1,8% para US$ 108,1 de US$ 106,1 por tonelada, como ontem, e sem novidades. 6º. As bolsas americanas apresentaram comportamento misto, 0,60% o Nasdaq e -0,60% o Dow, com investidores de novo comprando ações das big techs de Apple a Nvidia passando por Google, Meta e Microsoft porque todas vão divulgar resultados do 3T24 na próxima semana. 7º. O dólar à vista voltou para R$ 5,70 de R$ 5,60, ontem, seguindo o dólar no exterior que subiu 0,26% frente moedas fortes e 0,45% versus moedas emergentes. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou negativo em R$ 240 milhões na quarta-feira, 23 de outubro, conforme dados da B3. No mês de outubro, o saldo acumulado pelos estrangeiros está negativo em R$ 31,1 bilhões. No ano, os estrangeiros tiraram da Bovespa R$ 23,4 bilhões. Os estrangeiros respondem por 58,30% do volume negociado em outubro e por 55,20% do volume no ano. MAIORES ALTAS CVCB3 +5.05% R$ 2,08 USIM5 +4.24% R$ 6,64 VALE3 +3.40% R$ 61,73 SUZB3 +3.05% R$ 59,15 BRAP4 +3.03% R$ 19,38 MAIORES BAIXAS IRBR3 -6.49% R$ 41,35 CRFB3 -6.16% R$ 7,01 HYPE3 -5.55% R$ 26,20 YDUQ3 -3.90% R$ 10,60 HAPV3 -3.70% R$ 3,64 Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram:   / levante.investimentos   Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

Conheça o método SGR através do grupo exclusivo: https://lvnt.app/evowa8 23/10: Bolsa -0,55%, IRB +12% e SUZANO -4% Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde e Ricardo Afonso, e hoje é quarta, dia 23 de outubro, e o programa de hoje é ao Carson, Nicoletti, Gilson, Helson, Joao Marcos (Klabin), Rossi, Lucileidi, Liana, Eliseo, Daniel e Sarkis.O Ibovespa fechou em leve queda de -0,55%, aos 129.951 pontos, com volume muito fraco de R$ 18 bi, R$ 7 bi abaixo da média de R$ 25 bi das terças. Por que a Bolsa performou assim? 1º. A bolsa já abriu em caindo bem, como ontem, batendo a mínima às 11h45, aos 128,6 mil pontos, depois começou a recuperar-se para fechar nos 129.233 pontos, -0,31%. No Brasil, a queda do Ibovespa foi puxada pelas ações de commodities, PETR4 -1,2%, VALE3 -1,7% e PRIO3 -1%, com o petróleo recuando -1% e minério -2%. Caíram varejista também com MGLU3 -1,6%, depois que o Citi reduziu preço-alvo de R$ 18 para R$ 11,50 e pares do setor foram juntas. Só subiu Carrefour (CRFB3), com 5%, depois de desempenho de vendas dos supermercados e atacarejos no 3T24 melhor que o esperado e operação de sales-leaseback de R$ 725 milhões. 2º. Na B3, apenas 6 ações subiram entre as 15 ações mais negociadas com destaques para: HAPV3 +3% com investidores aproveitando as quedas das últimas semanas e expectativa de resultados mais positivos no 3T24, WEGE3 0,50% e ITUB4 0,70%. 3º. Já 9 ações caíram entre as mais negociadas com destaques para: VALE3 -1,8% a R$ 59,36 em função da queda de 2% do minério de ferro e PETR4 -1,2% R$ 35,66 seguindo o recuo do petróleo de -1,2%. 4º. O preço do petróleo caiu 1,1%, a US$ 75,2 de US$ 75,6, ontem, dentro do limite da volatilidade diária de -/+2%, com o aumento da estoque de petróleo em 5,5 milhões de barris nos EUA na semana passada. 5º. O minério de ferro recuou -2% para US$ 104,8 de US$ 107 por tonelada, como ontem, em função de incertezas quanto ao impacto dos novos estímulos monetários na economia chinesa. 6º. As bolsas americanas caíam, -1,60% o Nasdaq e -0,96% o Dow, com investidores na defensiva frente a alta dos juros de 10 anos que subiu pela quarto dia consecutivo, de 4,21% versus 4,25%, ontem, mais alguns resultados decepcionantes com Boing, C oca-Cola e preocupação com demanda fraca por iPhone 16 no trimestre. 7º. O dólar à vista ficou estável em R$ 5,70 e sem novidades. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou positivo em R$ 490 milhões na segunda-feira, 21 de outubro, conforme dados da B3. No mês de outubro, o saldo acumulado pelos estrangeiros está negativo em R$ 2,6 bilhões. No ano, os estrangeiros tiraram da Bovespa R$ 22,9 bilhões. Os estrangeiros respondem por 58,30% do volume negociado em outubro e por 55,20% do volume no ano. MAIORES ALTAS IRBR3 +12.29% R$ 47,71 CRFB3 +5.24% R$ 7,43 COGN3 +4.41% R$ 1,42 YDUQ3 +4.05% R$ 10,79 HAPV3 +3.25% R$ 3,81 MAIORES BAIXAS HYPE3 -3.91% R$ 27,01 LWSA3 -2.95% R$ 4,28 AZUL4 -2.66% R$ 5,48 VIVA3 -2.55% R$ 24,88 RADL3 -2.41% R$ 24,65 Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram: https://www.instagram.com/levante.investimentos/ Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

Conheça o método SGR através do grupo exclusivo: https://lvnt.app/evowa8 16/10 - Bolsa 0,54%, EMBR 6% e LWSA -2%, Dólar R$ 5,66 Olá, seja bem-vindo a mais um Fechamento de Mercado, comigo Flávio Conde e Ricardo Afonso, hoje é quarta-feira, dia 16 de outubro, e o programa de hoje é dedicado a Carson, Helio Caruso, Sergio Santos, Sarkis e Nicoletti. O Ibovespa fechou em leve alta de 0,54%, aos 131.750pontos, com volume muito de R$ 52 bi, R$ 27 bi acima da média de R$ 25 bi das quartas, por conta do vencimento de ídice Bovespa hoje. Por que a Bolsa performou assim? 1º. A bolsa abriu e oscilou até às 11h40 entre positivo e negativo para em seguida atingir a máxima 132,2 mil, às 14h40, e começar a ceder aos poucos até fechar em 131.750 pontos. No exterior, o dia começou sem novidades com bolsas de lado, petróleo perto da estabilidade e queda de -1% do minério. No Brasil, as ações mais negociadas se dividiram entre altas e baixas com exportadoras subindo dos R$ 5,66 do dólar. 2º. Na B3, 8 ações subiram entre as 15 ações mais negociadas com destaques para: VALE3 1,9% R$ 62,34, BBAS3 1,1% R$ 26,76, WEGE3 1,1% R$ 57,19 e SBSP3 1% R$ 92. Já 7 ações caíram entre as mais negociadas com destaques para: ITUB4 -0,60%, PETR4 -0,50%, BBDC4 -0,30% e PRIO3 -1,2%. 3º. O preço do petróleo fechou quase estável, -0,2%, a US$ 74,4 de US$ 74,7, ontem, dentro do limite da volatilidade diária de -/+2%, e sem novidades. 4º. O minério de ferro caiu mais um pouco e voltou para US$ 110 de US$ 111 por tonelada, ontem, e sem novidades. 5º. As bolsas americanas subiram, 0,28% o Nasdaq e 0,79% o Dow, com investidores mais animados com os resultados dos bancos depois que o Morgan Stanley com lucro acima do esperado, mas ações de tecnologia subiram menos porque as ações de fabricantes de chips recuaram novamente por conta da redução do guidance de vendas de chips para 2025 pela ASML, cia. holandesa. 6º. O dólar à vista ficou estável em R$ 5,66 com investidores à espera de algum corte de despesas pelo governo federal. 7º. Nos EUA, os juros dos títulos de 10-anos caíram um pouco para 4,02% a.a. ante 4,04% a.a., ontem, e sem novidades. No Brasil, as taxas de juros do títulos do Tesouro Nacional voltaram a subir com os juros do Prefixado 2031 indo de 12,74% para 12,85% a.a. com investidores ainda céticos quanto as contas públicas do governo federal. 8º. O saldo de investimentos estrangeiros no mercado secundário da Bovespa, de ações já em circulação, ficou negativo em R$ 3,3 bilhões na segunda-feira, 14 de outubro, conforme dados da B3, em função de oferta pública subsequente (follow-on) da ENEVA. No mês de outubro, o saldo acumulado pelos estrangeiros está negativo em R$ 240 milhões e Ibovespa -0,5%. No ano, os estrangeiros tiraram da Bovespa R$ 26,7 bilhões. Os estrangeiros respondem por 57,90% do volume negociado em outubro e por 55,20% do volume no ano. MAIORES ALTAS EMBR3 +6.74% R$ 48,77 AZUL4 +3.91% R$ 6,11 VAMO3 +3.88% R$ 5,89 YDUQ3 +3.22% R$ 10,58 COGN3 +2.96% R$ 1,39 MAIORES BAIXAS LWSA3 -2.25% R$ 4,35 IRBR3 -1.66% R$ 43,27 AZZA3 -1.59% R$ 41,36 ELET3 -1.50% R$ 38,12 HYPE3 -1.40% R$ 26,76 Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram:   / levante.investimentos   Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

This is a preview. For the entire episode support the show on Patreon! https://www.patreon.com/posts/history-of-35-113659720 Grab tickets to our live show in Belfast: www.universe.com/events/lions-led…t-tickets-83V5QD Can't make it to Belfast? We're streaming it! Get your stream tickets here: https://www.eventbrite.com/e/livestream-lions-led-by-donkeys-live-in-belfast-tickets-1008166803047?aff=oddtdtcreator&keep_tld=1 Check out our merch store https://llbdmerch.com/

Dans cette série de reportages-choc, la journaliste Georgia Blette revient sur le parcours de six des "Anciens de Louis-Fer", l'association des victimes de l'affaire du pâté contaminé. La Chute de LapinvilleLapin, pervers narcissique en fin de droits, raconte son retour à Lapinville et sa décision de faire un podcast pour se venger de ses anciens camarades d’école. Il est bientôt rejoint par Chloé Bloomington, star de cinéma qu’une énorme shitstorm oblige à revenir dans sa ville natale pour jouer dans une fiction quotidienne à la con. Puis, on suit l’enquête de Spiruline, astucieuse stagiaire à la mairie, qui dévoilera des scandales insoupçonnés dans les plus hautes sphères de Lapinville… Tour à tour, les Lapinvillois témoignent pour essayer de comprendre comment, une chose en entraînant une autre, ils ont fini par provoquer la destruction de la Terre. Leurs destins entremêlés forment une pelote visible de l’espace dont cette série, cinq minutes par jour, va dérouler le fil.Fresque épique et palpitante, chronique de la catastrophe en cours et de ses ramifications les plus inattendues, La Chute de Lapinville a pu être décrite comme une variante des Simpson à la sauce rond-point ou un jumeau maléfique de Plus belle la vie. Enregistrements décembre 2023-2024 Scénario et dialogues Benjamin Abitan, Wladimir Anselme, Laura Fredducci Conseillère littéraire Noémie Landreau Direction artistique Benjamin Abitan Réalisation Arnaud Forest Assistante réalisation Alexandra Garcia-Vilà Distribution Clémence Bucher Comédiens principaux Gabriel Dahmani (Max), Caroline Piette (Georgia Blette), Samuel Roger (Sarkis Mikaëlian), Anne-Lise Kedvès (Mère de Sarkis), Flore Babled (Chloé), Adeline Chagneau (Lucie Jean), Benjamin Wangermée (Jérémy Brugnon), Arnaud Churin (Brugnon Senior), Léa Luce Busato (Musicienne) Comédiens secondaires Pierre Hiesler, Antoine Raffalli, Jean-Baptiste Verquin, Sylvain Saussereau, Léo Reynaud Moyens techniques Obsidienne, Rémi Durel, Julie Tribout, Alice Lebaube Illustration Roxane Lumeret Musique originale Samuel Hirsch Production ARTE Radio, ARTE Studio, Virginie Lacoste, Sahar Pirouz, Jacques Falgous Musiques Samuel Hirsch

TalkLP Host Amber Bradley introduces a new series, Team Talk – Leadership Styles Uncovered in this episode of the TalkLPNews Podcast. She sits down with Jeff Mieseler, Director of Global Security, and Sarkis Grigorian, Senior Manager, Global Retail Security/Profit Protection and E-Commerce Fraud from Topgolf Callaway Brands to dig deep into the interplay of relationships within their department. Jeff discusses the three key steps to his leadership style, as well as his communication strategy when leading so many different skill sets within the program. While Sarkis talks about “No Egos,” managing up and the mantra of his communication with Jeff, “You never want the boss to be surprised.” Amber gets them both in the HOT SEAT as they reveal their Secrets (to leadership success). Hint: WWJD? What would Jeff Do? Listen today! Connect with Jeff here and Sarkis here.

Kuruçeşme Adası nam-ı diğer Galatasaray Adası, 19. yüzyılda Sarkis Balyan'ın saray mimarı olarak hizmetleri, sarayın ekonomik sıkıntıları içinde başına gelenler ve başka şeyler...    

Yara Khoury Nammour interviews Beirut-based Lebanese designer Nisrine Sarkis. They discuss her journey into the world of branding and lettering. Focusing initially on illustration and graphic design, Nisrine gradually realized the importance of Arabic typography to her practice after starting to work professionally as a graphic designer. Nisrine discusses her interest in display Arabic typefaces that she intends to develop out of her lettering projects. They also explore her teaching Arabic typography in Beirut, her design process, and her vision for design in the Arab world.Episode Notes***** About Khatt Chronicles *****Khatt Chronicles podcast features remarkable designers, illustrators, and researchers from the Arab World. We host engaging conversations about their practice, vision, and aspirations. In line with the rest of the Khatt foundation projects, focuses on new developments with Arab typography and design. By Arab, we mean people working with the Arabic language, script, and audience, who are not necessarily Arabs. These initiatives are dedicated to the younger generation as an alternative medium. It also focuses on the younger generations of designers to fulfill three primary objectives:1. Promote designers in the Arab World to the region and the rest of the world.2. Continue the mission of Khatt foundation as a network between designers to support fostering and exploring new ideas.3. Present these podcasts for inspiration and educational reasons.The podcast is an ongoing platform covering design initiatives and developments around the world. Our aim is to identify and highlight designers from the Arab World that have made meaningful contributions in their fields or have demonstrated excellence in design.Through storytelling, the Khatt Chronicles podcast will get you to know the designers on a personal level, and get to learn about how they think, and what makes them tick.Khatt Chronicles podcast is in collaboration with afikra.FollowInstagram: @khatt_chroniclesTwitter: @khttnetYouTube: Khatt Chronicles - YouTubeKhatt.net_Khatt Chronicles: https://www.khtt.net/en/page/28678/khatt-design-chroniclesTHIS SERIES IS PART OF THE AFIKRA PODCAST NETWORKExplore all episodes in this series: https://youtube.com/playlist?list=PLfYG40bwRKl40ZRFvo_VVYg6i56flEjSK&si=hSVcqPQlXdqq3sgTABOUT AFIKRAafikra | عفكرة is a movement to convert passive interest in the Arab world to active intellectual curiosity. We aim to collectively reframe the dominant narrative of the region by exploring the histories and cultures of the region – past, present and future – through conversations driven by curiosity.

SBS Assyrian honours the memory of Gorial Shimoun, an esteemed Assyrian writer, theatre director, songwriter, and media personality, who passed away on August 6, 2024, in Jordan. We interviewed Mr. Yousipos Sarkis, a Sydney-based writer and researcher of Assyrian music, and a close friend of Gorial's during the 1970s and 1980s. Mr. Sarkis shared insights into Gorial Shimoun's achievements and creative contributions

Delanie Fischer is sharing an epic mashup with you today. In the first half of the episode you'll hear from clinical psychologist, Dr. Ramani Durvasula, who provides an overview of narcissism and narcissistic personality disorder — the different types, signs and symptoms, definitions of popular buzzwords, etc., and you'll hear from Lee Hammock in the second half of the episode, who is a self-aware narcissist with a clinical diagnosis of NPD. Lee shares what it's like to live with this disorder, the whys behind his behaviors, and guidance for people who are in relationship with someone like him. This episode supports, and destigmatizes, those who have been impacted by this disorder.Plus:+ A Breakdown of The 8 Types of Narcissism+ The Root Cause of Narcissism and NPD+ How To Stop A Toxic Relationship PatternMore episodes related to this topic:The Impact of Gaslighting with Dr. Sarkis: https://podcasts.apple.com/us/podcast/the-psychological-impact-of-gaslighting-with/id1251196416?i=1000528606106Living with Borderline Personality Disorder Featuring Chris: https://www.selfhelplesspodcast.com/episodes/episode/26123a37/living-with-borderline-personality-disorder-featuring-chrisLiving with Narcissistic Personality Disorder with Lee Hammock: https://podcasts.apple.com/pk/podcast/living-with-narcissistic-personality-disorder-with/id1251196416?i=1000519855834Demystifying Borderline Personality Disorder with Dr. Ramani: https://podcasts.apple.com/lu/podcast/demystifying-borderline-personality-disorder/id1251196416?i=1000581362476Narcissism and NPD with Dr. Ramani: https://podcasts.apple.com/us/podcast/narcissism-and-narcissistic-personality-disorder-with/id1251196416?i=1000514861059How To Heal From Narcissistic Relationships with Dr. Ramani: https://podcasts.apple.com/au/podcast/how-to-heal-from-narcissistic-relationships-with-dr/id1251196416?i=1000647934771You can join our Patreon community here: https://www.patreon.com/selfhelplessYour Host, Delanie Fischer: https://www.delaniefischer.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Preencha o formulário e conheça o programa mais completo de consultoria e aconselhamento da Levante https://lvnt.app/jtnp7n 11/07 - 9ª. Alta Bolsa, TIM 4%, VIVO 3% e Dólar R$ 5,44 Olá, seja bem-vindo ao Fechamento de Mercado da Levante comigo Flávio Conde, hoje é 5º. feira, dia 11/7, e o programa é dedicado Alex, Gílson, Paulo Henrique, Mario, Roberto Nicoletti, Robson, Jadeon, Manoel, Leonida, Lucileide, Carson e Sarkis. A Bolsa mais um dia de alta, 0,85%, a oitava seguida, aos 128.293 pontos e volume regular de R$ 20 bi, R$ 5 bi abaixo da média de R$ 25 bi das quintas. Por que a Bolsa performou assim? 1º. A bolsa abriu em alta depois da divulgação do CPI americano de junho de -0,10% versus zero em maio e o Ibovespa foi subindo com os juros recuando nos EUA e Brasil e ações subindo lá e aqui porque agora espera-se dois de juros pelo Fed, o primeiro em setembro, e o segundo em dezembro. Na B3, as altas foram generalizadas com exceção de Vale, BB, Bradesco e Sabesp. 2º. Entre as 15 ações mais negociadas 11 subiram lideradas em volume negociado por: PETR4 0,80%, ITUB4 0,50%, B3SA3 3%, BPAC11 0,30%, EMBR3 1,80%, RENT3 2,90%, RALI3 3,40%, SUZB3 1,0%, MULT3 1%, MRVE3 2,80%, CYRE3 3%, BRFS3 0,10%. 3º. Quatro ações caíram entre as 15 mais negociadas: VALE3 -0,20%, BBAS3 -0,40%, BBDC4 -0,20%, SBSP3 -0,60% 4º. O preço do petróleo subiu 0,40% a US$ 85,70 de US$ 85,30, ontem, dentro da volatilidade diária de -/+2%, depois que a Nigeria interrompeu acordos com produtores para suprir petróleo a refinarias ao preço de mercado. 5º. O preço do minério de ferro subiu 1,30% hoje para US$ 113,90 de US$ 111,80 por tonelada, ontem, recuperando dois dólares da queda de ontem. 6º. As bolsas americanas fecharam em direções opostas com Nasdaq despencado -20% e Dow Jones com leve alta de 0,10% com investidores otimistas depois do CPI de -0,10% em junho e 0% em maio, pois aumenta a probabilidade do Fed começar a cortar os juros em setembro e fazer mais um corte em dezembro. Porém, investidores teriam começado a fazer uma rotação setorial vendendo ações de gigantes de tecnologia e comprando ações de grandes cias. da economia “real” como bancos, varejistas, restaurantes e indústrias. 7º. O dólar à vista subiu 3 centavos para R$ 5,44 de R$ 5,41, ontem, devido a um certo esgotamento da queda mais recente das cotações e alguns efeitos técnicos sobre o real do forte avanço do iene no exterior. 8º. Nos EUA, os juros dos títulos de 10-anos recuaram apenas 7 pontos para 4,21% de 4,28% a.a., ontem. No Brasil, ao contrário dos EUA, as taxas de juros dos títulos prefixados do Tesouro do Brasil subiram com o Prefixado 2031 indo de 11,67% para 11,83% a.a. e seguindo a alta do dólar no país. 9º. Os investidores estrangeiros venderam quase nada, R$ 31 milhões em recursos no segmento secundário da B3 (ações já listadas) na terça-feira, 9 de julho, dia em que o Ibovespa subiu 0,44%. Assim, o superávit mensal da categoria aumentou para R$ 2,7 bilhões e o Ibovespa sobe 2,70% em julho. Já no ano, o saldo negativo do ano diminuiu para R$ 37,3 bilhões. MAIORES ALTAS TIMS3 +4.3% R$ 16,76 RAIL3 +3.4% R$ 23,11 BRKM5 +3.2% R$ 19,27 VIVT3 +3.2% R$ 49,00 SANB11 +3.2% R$ 28,61 MAIORES BAIXAS TRPL4 -1,5% R$ 27,10 ALPA4 -1,5% R$ 9,29 HYPE3 -1.4% R$ 28,79 TOTS3 -1.1% R$ 29.84 SBSP3 -0,90% R$ 84.33 Agora, uma mensagem do nosso patrocinador, o Sala VIP da Levante Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram:   / levante.investimentos   Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

Join us for our Life of Purpose series this month as we revisit some of our most impactful episodes. Dive deep into expert insights and practical strategies on health, performance, and community, helping you achieve personal and professional fulfillment.Sarah Sarkis, psychologist, writer and performance consultant, works to empower people to achieve long term change and growth through an entirely science-backed approach. We discuss a few relatable topics like parenting, social media, education and growing up before moving on to some deeper questions that ultimately unveil the profound psychology and tactical methods behind changing your life. Subscribe for ad-free interviews and bonus episodes https://plus.acast.com/s/the-unmistakable-creative-podcast. Hosted on Acast. See acast.com/privacy for more information.

Preencha o formulário e conheça o programa mais completo de consultoria e aconselhamento da Levante https://lvnt.app/jtnp7n 04/07/24: Reunião de Lula faz dólar cair, ASAI +6% e JBS -4% Olá, seja bem-vindo ao Fechamento de Mercado da Levante comigo Flávio Conde, hoje é 5a. feira, dia 4/7, e o programa é dedicado a Rogerio, Hortacozinha, Eliseu, Sarkis, Emerson, Luish e Gílson. E hoje teremos a primeira participação do nosso novo analista de FIIs, Leonardo Verissimo. A Bolsa registrou leve alta de 0,40%, aos 126.164 pontos, a quarta seguida. O volume fraco de R$ 17 bi, quase R$ 8 bi abaixo dos R$ 25 bi das quintas de dezembro. O motivo foi o importante feriado de 4 de julho nos EUA. Já o dólar, graças a Deus, continuou recuando e fechou a R$ 5,49 vindo de R$ 5,54, com o anúncio de cortes de gastos de R$ 25,9 bilhões no orçamento de 2025 do governo federal. Por que a Bolsa performou assim? 1º. A bolsa já abriu em alta e atingiu 126,6 mil pontos às 10h10 para ficar todo dia no campo positivo entre 126,6 mil e 126,1 mil. O motivo da alta foi o anúncio de cortes de gastos de R$ 25,9 bi no orçamento de 2025 pelos ministros Haddad e Tebet apesar de uma certa desconfiança de economistas especialistas em contas públicas de que a necessidade de cortes seria muito superior ao anunciado porque os gastos estão crescendo mensalmente com a regra do arcabouço de reajustar as despesas pela inflação mais o crescimento da receita. Na Bolsa, subiram por mais um dia as ações que vinham caindo por conta do juros mais altos e agora sobem dos setores varejistas, educacional, construtoras e supermercados. Já na ponta negativa, caíram ações de setores de petróleo, celulose, mineração e siderurgia porque boa parte das receitas é exportada e/ou indexada ao dólar. 2º. Entre as 15 ações mais negociadas 10 subiram lideradas em volume negociado por: ITUB4 0,40%, B3SA3 2%, SBSP3 2,20%, RENT3 4% e BBAS3 0,20%. 3º. Cinco ações caíram entre as 15 mais negociadas: PETR4 -1,80%, VALE3 -0,40%, SUZB3 -1,40%, PETR3 -1,50% e PRIO3 -0,20%. 4º. O petróleo alta de 0,30%, para US$ 87,4 de US$ 87,1, ontem, dentro da volatilidade diária de -/+2%, e sem novidades. 5º. O minério praticamente estável para US$ 118,9 de US$ 118,8, ontem, e sem novidades. 6º. As bolsas americanas estiveram fechadas por conta do feriado de 4 de julho nos EUA. 7º. O dólar recuou e fechou a R$ 5,49 vindo de R$ 5,54, com o anúncio de cortes de gastos de R$ 25,9 bilhões no orçamento de 2025 do governo federal. 8º. Os juros dos títulos do Tesouro do Brasil finalmente caíram com as taxas do Prefixado 2031 indo de 12,39% para 12,21% a.a. seguindo a queda do dólar. 9º. Os investidores estrangeiros aportaram R$ 1,027 bilhão em recursos no segmento secundário da B3 (ações já listadas) na terça-feira, 2 de julho, dia em que o Ibovespa subiu 0,06%. Assim, o superávit mensal da categoria ficou em R$ 807,6 milhões e o saldo negativo do ano alcançou R$ 39,31 bilhões. MAIORES ALTAS VAMO3 +8.18% R$ 8,73 PCAR3 +7.33% R$ 2,93 LREN3 +6.52% R$ 13,24 EZTC3 +5.15% R$ 13,67 CRFB3 +5.09% R$ 10,12 MAIORES BAIXAS NTCO3 -2.56% R$ 15,25 CMIN3 -1.99% R$ 5,43 RADL3 -1.80% R$ 25,14 SUZB3 -1.43% R$ 56,52 PETR4 -1.32% R$ 37,34 Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram: https://www.instagram.com/levante.investimentos/ Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

Preencha o formulário e conheça o programa mais completo de consultoria e aconselhamento da Levante https://lvnt.app/jtnp7n 01/7/24: Lula critica, dólar R$ 5,65 e 2 Ações para Comprar Olá, seja bem-vindo ao Fechamento de Mercado da Levante comigo Flávio Conde, hoje é 6a. feira, dia 28/6, e o programa é dedicado a Morgana, Daniel, Alex, Victor, Sarkis, Eduardo e Luiz Vaz bem como a moeda real que estreou dia 1/7/1994 bem como aos formuladores do Plano Real que acabaram que acabou com a hiperinflação. Na minha opinião, o Brasil precisa hoje um Plano “Real” para reduzir as despesas governamentais bem como os impostos. Vamos à bolsa hoje. A Bolsa registrou leve alta de 0,65%, aos 124.718 pontos e volume bom de R$ 21 bi, R$ 1 bi acima dos R$ 2o bi das segundas de dezembro. O dólar fechou a R$ 5,65 com novas críticas de Lula ao presidente do Banco Central. Por que a Bolsa performou assim? 1º. A bolsa abriu em leve alta, mas negativou a 123,8 mil, às 10h15, para depois positivar mesmo com as falas de Lula de que “quem (quer) o Banco Central autônomo é o mercado financeiro. Em entrevista à rádio Princesa, de Feira de Santana (BA), o petista voltou a criticar a taxa Selic, que estaria “exagerada”, e a autonomia da autoridade monetária. Ele afastou a possibilidade, entretanto, de mudar a lei. Disse que terá paciência para indicar seu nome para o BC até o fim deste ano”. Mais uma fala de Lula, projeções de forte aumento do déficit da Previdência e possibilidade de nova taxação de bolsa, FIIs e FIAGROS fizeram o dólar ir R$ 5,59, no fechamento de sexta-feira, para R$ 5,65 e juros mais altos, Prefixado de 2031 de 12,45% para 12,55% a.a. Já a Bolsa teve um dia levemente positivo com investidores comprando ações de cias. que tem parte da receita ligada ao dólar – como SLC, CMIN, Vale, PRIO, Suzano, São Martinho e outras – e cias. endividadas em dólar e/ou com receitas ligadas apenas ao mercado interno – como supermercados, varejistas e construtoras. 2º. Entre as 15 ações mais negociadas 12 subiram lideradas em volume negociado por: VALE3 1,5% R$ 63,14; PETR4 1,5% R$ 38,63; SBSP3 3,90% R$ 77,88; EQTL3 4,3% R$ 32,03 e B3SAE3 2,2% R$ 10,47 3º. Três ações caíram entre as 15 mais negociadas: BBAS3 -1,3$ R$ 26,36; ITUB4 -0,50% R$ 32,23; e RENT3 -0,60% R$ 41,77. 4º. O petróleo alta de 0,70%, para US$ 86,6 de US$ 86,0, na sexta-feira, dentro da volatilidade diária de -/+2%, em função do aumento da tensão geopolítica com a possibilidade de Israel invadir o Líbano e escalar o confronto na região. 5º. O minério de forte alta 2% para US$ 115,5 de US$ 113,50, na sexta-feira, com aumento da demanda das siderúrgicas chinesas. 6º. As bolsas americanas subiram com o Nasdaq 0,80% e o Dow Jones 0,15%, com investidores comprando mais ações acreditando que a Inteligência Artificial (IA) aumentará produtividade e permitirá não apenas aumento de receita dos fornecedores de chips, mas também de cias. tradicionais e ainda reduzirá despesas administrativas. A conferir. 7º. O dólar subiu mais 6 centavos, para R$ 5,65 de R$ 5,588, ontem, com temor fiscal e mais críticas de Lula ao BC. 8º. Os juros dos 10-anos dos títulos do Tesouro dos EUA subiram mais ainda de 4,40% a.a. para 4,46% a.a. Os juros dos títulos do Tesouro do Brasil subiram com as taxas do Prefixado 2031 (cerca de 7 anos), indo de 12,46% para 12,55% a.a. em função da combinação de dólar alto e críticas de Lula ao BC. MAIORES ALTAS SLCE3 +7.22% R$ 18,71 CMIN3 +5.01% R$ 5,45 EQTL3 +4.37% R$ 32,03 RECV3 +4.15% R$ 19,31 SMTO3 +4.06% R$ 34,06 MAIORES BAIXAS ASAI3 -3.29% R$ 10,00 PCAR3 -2.96% R$ 2,62 VBBR3 -2.70% R$ 19,95 HAPV3 -1.83% R$ 3,76 TOTS3 -1.77% R$ 29,89 Conheça a Levante Investimentos: Conheça nossas *Séries de Investimentos*: https://lvnt.app/4q3u3b Acompanhe nosso Instagram: https://www.instagram.com/levante.investimentos/ Fique ligado nas principais notícas do mercado no nosso canal no Telegram: https://lvnt.app/zuntm0

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome's role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today's Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs

Have you ever considered traveling with a tour company to a particular destination? Christine Sarkis, with TourScoop.com and FamilyVacationist.com, gives us some tips for how to decide if a tour is a good fit for your family and if so, how to choose among the many tour companies like Backroads, Road Scholar, Go Adventures, Intrepid, Wilderness Travel and more.Want to get on the fast-track to always fly your family free? Come join us inside the Families Fly Free membership, the BEST way to learn how to fly free using travel rewards...https://www.familiesflyfree.com Download Lyn's FREE list of 7 INSIDER hacks she uses to personally fly her family free...https://familiestravefree.com/7hacks

Welcome back to the Podcast! Vik talks about his surgery and how its effected the shop. The guys talk about the new Lamborghini models, how the first Koenigsegg was designed, and other news. Sarkis is getting a new car, and we have a ton of shop updates. We've had some good builds and have more coming. Thanks for watching everyone, enjoy the show!

This episode of Flow Radio is a masterclass on leadership best practices, featuring three very special guests: Retired Navy SEAL commander and bestselling author Rich Diviney, Philadelphia 76ers assistant coach Coby Karl, and veteran performance psychologist Dr. Sarah Sarkis. This episode is a must-listen for anyone who wants to learn how to lead teams that consistently outperform and out-innovate the competition. how to lead teams that consistently outperform and out-innovate the competition. In This Episode: 0:00 Introduction 04:35 Defining leadership 11:05 Leadership as Behavior 26:13 Dynamic Subordination in High-Performing Teams 30:55 Lessons from Phil Jackson and Dennis Rodman 39:11 Defining Leadership Expertise 49:00 The Role of Flow in Leadership 57:44 Attunement and Shared Experience in Leadership 1:16:53 Balancing Training and Education in the Business World About the Guests:   By day, Dr. Sarah Sarkis is a licensed psychologist, a certified executive coach, and the senior Director of Performance Psychology at Exos. Occasionally, you'll also find her moonlighting as a writer and keynote speaker.  Dr. Sarkis has spent 20-plus years in the trenches, exploring every corner of the human psyche. Her passion and focus these days is working with CEOs, athletes, professional coaches, and other executives striving to achieve moonshot dreams. In a nutshell, she considers herself a human performance hybrid: part shrink, part coach, part Jedi of the unconscious.  Dr. Sarkis has been a featured guest on many popular podcasts, including The Gabby Reece Podcast and LinkedIn Live. She is also a regularly featured SME in publications such as CNBC, Women's Health, The Huffington Post, and the New York Times. Rich Diviney, a bestselling author, leadership expert, and retired Navy SEAL commander, brings over two decades of exceptional experience to the stage. Over the course of a 20-year career, he completed more than thirteen overseas deployments and served in multiple leadership positions, to include being the officer in charge of an extremely specialized SEAL selection process, curating the most elite performers through a specialized selection process. Coby Karl is an Assistant Coach for the Philadelphia 76ers. Starting as a Seattle Sonics ballboy to becoming an NBA player, he's spent a lifetime learning the game and how to lead a team. His experiences helped him coach the Delaware Blue Coats to win their first NBA G League title in 2023. Coby learned to lead with compassion and thoughtfulness from his mentors, icons like Phil Jackson and his dad, George Karl. Flow Radio Is Presented By Flow Research Collective Are you an entrepreneur, a leader, or a knowledge worker, who wants to harness the power of flow so you can get more done in less time with greater ease and accomplish your boldest professional goals faster? If the answer is yes, then our peak-performance training Zero To Dangerous may be a good fit for you. Flow Research Collective is a leading neuroscience research and training company. If you're interested in learning the science-backed techniques we used to train top executives at Facebook, Audi and even the Navy SEALs, click the link here: ⁠https://www.flowresearchcollective.com/zero-to-dangerous/overview⁠ Follow Flow Research Collective: YouTube: ⁠https://www.youtube.com/@flowresearchcollective⁠ Instagram: ⁠https://www.instagram.com/flowresearchcollective⁠ LinkedIn: ⁠https://www.linkedin.com/company/flowresearchcollective⁠ X: ⁠https://twitter.com/thefrc_official⁠ Facebook: ⁠https://www.facebook.com/flowresearchcollective⁠ Spotify: ⁠https://open.spotify.com/show/6RQY0d5rdlEiinHEtfWy6A⁠ Website: ⁠https://www.flowresearchcollective.com⁠ Flow Research Collective was founded by Steven Kotler, one of the world's leading experts on human peak performance. He is an award-winning journalist and author with over ten bestselling books.

Welcome back to the Podcast! Sarkis is making a guest appearance on the show today and it cost us, so we hope you enjoy. Hear about some wild supercars, a cyber truck boat, and the guys ordered a G Wagon golf cart. Thanks for watching everyone, enjoy the show!

EG.975 Sarkis Mikael