Podcasts about Nobel Committee

And the Nobel Peace Prize goes to . . . María Corina Machado? Wait, what's going on here? Why does it seem like, far from celebrating a champion of peace, the Nobel Committee is in fact paving a path to war? Let's find out!

And the Nobel Peace Prize goes to . . . María Corina Machado? Wait, what's going on here? Why does it seem like, far from celebrating a champion of peace, the Nobel Committee is in fact paving a path to war? Let's find out!

In 1945, the Nobel Committee awarded its prize for literature to Gabriela Mistral (1889-1957) "for her lyric poetry which, inspired by powerful emotions, has made her name a symbol of the idealistic aspirations of the entire Latin American world." Born in a rural Andean valley and abandoned by her free-spirited father at the age of three, Mistral struggled for the right to be a teacher - and then went on to help reform the Chilean educational system to improve the lives of women and the impoverished. After experiencing heartbreak and several tragedies, her poetry collection Desolación ("Desolation" or "Despair") (1922) made her one of Latin America's most revered writers. In this episode, Jacke looks at the life and works of this remarkable poet, whose constant search for truths in nature and humanity informed a body of work that continues to delight and inspire. Join Jacke on a trip through literary England (signup closing soon)! The History of Literature Podcast Tour is happening in May 2026! Act now to join Jacke and fellow literature fans on an eight-day journey through literary England in partnership with ⁠⁠⁠John Shors Travel⁠⁠⁠. Scheduled stops include The Charles Dickens Museum, Dr. Johnson's house, Jane Austen's Bath, Tolkien's Oxford, Shakespeare's Globe Theater, and more. Find out more by emailing jackewilsonauthor@gmail.com or masahiko@johnshorstravel.com, or by contacting us through our website ⁠⁠⁠historyofliterature.com⁠⁠⁠. Or visit the ⁠⁠⁠History of Literature Podcast Tour itinerary⁠⁠⁠ at ⁠⁠⁠John Shors Travel⁠⁠⁠. The music in this episode is by Gabriel Ruiz-Bernal. Learn more at ⁠⁠⁠gabrielruizbernal.com⁠⁠. Help support the show at ⁠⁠⁠patreon.com/literature ⁠⁠⁠or ⁠⁠⁠historyofliterature.com/donate ⁠⁠⁠. The History of Literature Podcast is a member of Lit Hub Radio and the Podglomerate Network. Learn more at ⁠⁠⁠thepodglomerate.com/historyofliterature⁠⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

part one:  James Baratta is a writing fellow at The American Prospect discusses Democratic Senators Probe ‘Apparent Neglect' of Detained Flotilla ActivistsIt took the State Department four days to assess the well-being of American citizens apprehended by Israel for participating in the Global Sumud Flotilla.part twoJeet Heer is a national affairs correspondent for The Nation discusses The Nobel Peace Prize Just Surrendered to Trump Trump is mad that he didn't win. But by honoring María Corina Machado, the Nobel Committee has endorsed his war against Venezuela—and continued Europe's MAGA groveling. 

Donald Trump did not win the Nobel Peace Prize, as he boasted he should for supposedly being the “peace President” - a claim we've debunked numerous times on this show. White House Communications Director Steven Cheung said that the Nobel Committee “places politics over peace” - which actually does have some truth to it, like a broken clock does twice a day. The award was instead given to María Corina Machado, a Venezuelan “opposition” leader hell-bent on overthrowing the government of Nicolás Maduro. Her party, Vente Venezuela, has signed a cooperation agreement with the Israeli Likud party, and in 2019 she posted on X that “The struggle of Venezuela is the struggle of Israel.”In Gaza, Palestinians celebrated in the streets upon hearing the news of the ceasefire, and are beginning to return to the north. While they are finding their homes largely reduced to rubble, they are vowing to rebuild and reestablish their lives in their homeland. As the remaining Israeli captives are being traded for thousands of Palestinian political prisoners, hundreds of whom were held in Israel for much longer than two years, the ceasefire deal also calls for Israel to allow hundreds of humanitarian aid trucks into Gaza daily.The ceasefire was won first and foremost by the resistance and resilience of the Palestinian people, and by the solidarity movement across the world that did not let Palestine out of the spotlight for the past two years. But Israel is already going back on some of the terms, killing at least five Palestinians in Shujaiya on Tuesday who were going to check on their homes. The occupying forces also announced they will not actually allow for the aid that it agreed to as part of the ceasefire to be let into Gaza.This situation is quickly developing, and what happens next may also open a new phase in the solidarity movement, and we'll get into many of the questions about how the movement should go forward and what these changes mean.Support the show

The best way I know to illustrate how arbitrary the Nobel prizes are, is the example of the Academy Awards. When the Hollywood industry elites gather each year to award Oscars, they'll issue awards for the “best actor and actress” and for the “Best picture”, etc. Does that mean that the best actor over the previous year was the actor or actress was issued the award or that the “best picture” released during the year is what the Academy says it is? Of course not, right? It's what members of the Academy say is so. As we know, it's a highly subjective process. Nobel prizes are no different. They're highly subjective prizes awarded by select insiders that hold no empirical significance.  

The only people not to recognize Donald Trump's efforts for world peace seem to congregate in Oslo. Andrew Malcolm scolds the ignoble Nobel Committee, but remains a bit skeptical about how Trump pulled off his magic trick with Gaza. What side deals may have made this possible? Plus, we wonder how Democrats pushing the shutdown will deal with such an ascendant president without looking like ankle-biters. Finally, Andrew has technical issues whenever the Cleveland Browns come up, for some reason...

The actual UN is a tedious talk-shop with 193 members and tedious rules of procedure. Trump's model is far more efficient: one member, one Twitter account, and the divine authority of his own gut feelings. He doesn't need a Security Council; he has a council of one, often convened at 3 AM. The Nobel Committee, steeped in the old-world, collaborative nonsense, is clearly threatened by this streamlined, disruptive start-up approach to global statecraft.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You're listening to American Ground Radio with Louis R. Avallone and Stephen Parr. This is the full show for October 10, 2025. 0:30 We respond to a wave of chilling incidents that expose how violent rhetoric is spilling out of politics and onto our streets and campuses. From the horrific threat mailed to commentator Benny Johnson and flyers distributed at Georgetown University mocking Charlie Kirk's death to Jay Jones' disturbing text messages where he fantasized about shooting a GOP leader. Normalizing threats and celebrating violence erodes democratic debate, endangers everyday people, and invites escalation — and we challenge public figures, media, and institutions to condemn violence plainly and without excuses. 9:30 Plus, we cover the Top 3 Things You Need to Know. Federal workers are being laid off as the government shutdown entered its 10th day. Dominion voting Systems has been bought by Republican Scott Leiendecker. A Virginia man has been arrested for threatening to kill a Republican member of the State Legislature and his children. 12:30 Get Brain Reward from Victory Nutrition International for 20% off. Go to vni.life/agr and use the promo code AGR20. 13:30 We break down President Trump’s decision to raise tariffs on Chinese goods from 30% to 100%, a massive escalation in the ongoing trade and technology standoff with Beijing. 16:30 American Mamas Teri Netterville and Kimberly Burleson tackle a question that hits home for many conservative parents: “Dear Mamas, we’re conservative. Our grown children have bought into the leftist nonsense full force. Help!” The Mamas dive deep into the emotional struggle of watching children abandon their family’s values and faith, and they remind listeners that while the world may divide us politically, faith, love, and prayer can bridge any gap. If you'd like to ask our American Mamas a question, go to our website, AmericanGroundRadio.com/mamas and click on the Ask the Mamas button. 23:00 We take a hard look at the chaos unfolding in New York City’s mayoral race. 25:30 We Dig Deep into this year's Nobel Peace Prize — and why President Donald Trump didn’t win it, despite a long list of international peace deals under his watch. The 2025 Nobel Committee awarded the prize to María Corina Machado, a Venezuelan opposition leader fighting for democracy against the Maduro regime. While her courage is praised, we question why the Nobel Committee overlooked the tangible peace achievements credited to Trump. 32:30 Get NSorb from Victory Nutrition International for 20% off. Go to vni.life/agr and use the promo code AGR20. 33:30 We dive into free speech on college campuses, spotlighting a controversial petition at Rutgers University to ban Turning Point USA from campus.The irony? The group being targeted is the one promoting open dialogue and free expression — and one of the loudest voices supporting the ban is reportedly an associate professor of Christianity. 36:00 Plus, it's Fake News Friday! We're putting you to the test with our weekly game of headlines—are they real news, fake news, or really fake news? From the Nobel Peace Prize and the cease fire between Israel and Hamas, to Jeffrey Epstein, Vladimir Putin, and even paragliding into a campaign event, can you spot the fake news? Play along, keep score, and share your results with us on Facebook page: facebook.com/AmericanGroundRadio. 40:30 And we finish off with Melania Trump's letter to Vladimir Putin that will make you say, "Whoa." Follow us: americangroundradio.com Facebook: facebook.com / AmericanGroundRadio Instagram: instagram.com/americangroundradioSee omnystudio.com/listener for privacy information.

Was Donald Trump robbed of the Nobel Peace Prize? After helping bring an end to the Israel–Gaza conflict, many assumed Trump would finally earn the world's top peace honor. Instead, the Nobel Committee gave it to Venezuelan politician María Corina Machado — a move that shocked observers and exposed deep global biases. So… what really happened behind the scenes? Studio Sponsor: Cardio Miracle - "Unlock the secret to a healthier heart, increased energy levels, and transform your cardiovascular fitness like never before.": CardioMiracle.com/TBNS In this episode of The Brian Nichols Show, we cut through the headlines and get to the truth with foreign policy expert Joseph Bouchard. From Venezuela's chaotic political landscape to Trump's overlooked peace efforts, this conversation takes a no-spin look at how geopolitics and media narratives shape what the world calls “peace.” Joseph breaks down who Machado really is — and why her record as a U.S.-backed interventionist clashes with the “pro-democracy” label the Nobel Committee handed her. You'll also hear how U.S. sanctions, coups, and economic warfare have driven Venezuela's collapse, while elites in Washington pretend they're defending freedom. Then Brian and Joseph tackle the million-dollar question: if peace prizes go to politicians who destabilize countries or win on PR, is the Nobel Peace Prize even worth anything anymore? From Kissinger to Obama to today's picks, the award's credibility has been unraveling for decades — and this year may have sealed the deal. Finally, they ask what peace should look like in a world run by double standards — and who's actually doing the hard, thankless work of achieving it. If you're tired of fake narratives and ready for real talk about global power, this is one episode you can't afford to miss. ❤️ Order Cardio Miracle (CardioMiracle.com/TBNS) for 15% off and take a step towards better heart health and overall well-being!

Trump chronicler Michael Wolff joins the Beast's Joanna Coles to unpack Trump's latest delusions of grandeur. This time, namely, his fantasy of winning a Nobel Peace Prize for “ending seven wars” that never existed.Wolff recounts a disturbing encounter involving Jeffrey Epstein, the head of the Nobel Committee, and alleged Polaroids of Trump, while Pam Bondi, now heading the DOJ, pointedly refuses to discuss them.From showy Middle East tours to Chicago photo ops with the National Guard, Joanna and Michael explore how Trump's obsession with power, spectacle, and apparent paranoia, tinged with fear, continues to reshape his presidency. Is Trump intending to occupy cities like Chicago indefinitely or just seeking attention?  Hosted on Acast. See acast.com/privacy for more information.

- Gerry blasts the Nobel Committee for snubbing Trump, despite claiming he's ended multiple global conflicts and brought peace to Gaza. - He praises Trump's “art of the deal” diplomacy while mocking liberals who refuse to credit him, calling it the most historic peace achievement in decades. - New York AG Letitia James was indicted. - Gerry slams Jimmy Kimmel for denying Antifa's existence Today's podcast is sponsored by :   QUINCE : Layer up this fall with clothing & accessories that feel as good as they look! Go to ⁠⁠⁠⁠http://quince.com/gerry⁠⁠⁠⁠ for free shipping on your order and 365-day returns. Now available in Canada, too. Listen to Newsmax LIVE and see our entire podcast lineup at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://Newsmax.com/Listen⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Make the switch to NEWSMAX today! Get your 15 day free trial of NEWSMAX+ at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://NewsmaxPlus.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Looking for NEWSMAX caps, tees, mugs & more? Check out the Newsmax merchandise shop at : ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://nws.mx/shop⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow NEWSMAX on Social Media:  -Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://nws.mx/FB⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  -X/Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://nws.mx/twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://nws.mx/IG⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/NewsmaxTV⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -Rumble: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://rumble.com/c/NewsmaxTV⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -TRUTH Social: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://truthsocial.com/@NEWSMAX⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -GETTR: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://gettr.com/user/newsmax⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -Threads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://threads.net/@NEWSMAX⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  -Telegram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://t.me/newsmax⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  -BlueSky: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bsky.app/profile/newsmax.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -Parler: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://app.parler.com/newsmax⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

The Nobel Committee passed over President Donald Trump for the Nobel Peace Prize on Friday despite brokering eight different peace treaties his first year back in office, and it's only October. President Trump has brokered eight different peace treaties in 2025. He is even credited with the peace agreement between Israel and Hamas that will go into effect this weekend. Layoffs of federal employees officially began Friday as the U.S. government shutdown entered another tense phase, according to Trump administration budget chief Russell Vought.Sponsor:My PillowWww.MyPillow.com/johnSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

🚨 The U.S. just approved a deal letting Qatar — one of the chief financier of Hamas, the Taliban, and the Muslim Brotherhood — open an air force facility on American soil at Mountain Home Air Force Base in Idaho.  The same week, the Nobel Committee overlooked Trump's record-breaking peace achievements to honor a Venezuelan activist. The message is clear: America's global elites are trading sovereignty for symbolism. While Trump pursues real peace, Washington invites compromise — and prophecy is unfolding before our eyes.   📱: It's never been easier to understand. Stream Only Source Network and access exclusive content: https://watch.osn.tv/browse 📚: Check out Jerusalem Prophecy College Online for less than $60 per course: https://jerusalemprophecycollege.com Learn more about your ad choices. Visit megaphone.fm/adchoices

On this episode of Fox Across America, Jimmy Failla reacts to the Nobel Committee awarding this year's peace prize to Venezuelan opposition leader Maria Corina Machado, even after President Trump help negotiate a peace deal between Israel and Hamas. Media Research Center TV host Justine Brooke Murray stops by to give her take on California Democratic gubernatorial candidate Katie Porter's epic meltdown during a recent interview with CBS News. PLUS, Lincoln Failla checks in to talk about his clutch performance for the Clarke Rams in last weekend's win over the Wantagh Warriors. [00:00:00] Nobel Prize Committee snubs Trump [00:38:03] Justine Brooke Murray [00:56:30] Government shutdown stalemate continues [01:15:07] Reacting to a woke review of Leonardo DiCaprio's new movie [01:39:03] Lincoln Failla Learn more about your ad choices. Visit podcastchoices.com/adchoices

Michael offers a bold take on today's Smerconish.com poll question which asks: "If peace holds in the Middle East, should President Trump receive the Nobel Peace Prize next year?" From 2025 Nobel winner Maria Corina Machado to Thomas Friedman's surprising take, Michael explores whether Trump's diplomacy deserves global recognition — and what the Nobel Committee's decision really says about politics and peace. Listen here, then vote there! Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

President Trump’s historic peace deal shocks the world—freeing every hostage and ending wars across the Middle East—yet the Nobel Committee snubs him on a technicality. While the media mocks and twists the facts, Mike breaks down how Trump stopped eight wars in nine months and still can’t get credit. Plus, a viral airline controversy over a “Build Back Better My A**” hat ignites a debate on free speech and decency, and Letitia James—the Democrat who built her career on “getting Trump”—finds herself under indictment.See omnystudio.com/listener for privacy information.

Dan is ready for the weekend and an honest Nobel Committee + more evidence of the "tolerant" left on display | aired on Friday, October 10th, 2025 on Nashville's Morning News with Dan Mandis. See omnystudio.com/listener for privacy information.

A clever move by the Nobel Committee. See omnystudio.com/listener for privacy information.

The 2025 Nobel prizes are announced this week – how did Science in Action's predictions fare? Science author and thinker Philip Ball judges.Also, a new “Human Disease Blood Atlas” gets a boost, as described by Mathias Uhlén of SciLifeLab.Meanwhile Nozair Khawaja of Free University of Berlin has been revisiting data from the Cassini mission to Enceladus, one of Saturn's moons, back in 2008. His new analysis increases the prospects of habitable conditions deep on the ocean floor beneath the icy crust.Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jana Bennett-Holesworth(Image: Chair of the Nobel Committee for Chemistry explains a model during a press conference. Credit: Jonathan Nackstrand via Getty Images).

David Waldman brings us the Wednesday KITM, on Wednesday, as expected, and as expected on a Wednesday, Greg Dworkin, who's here to ask, “Health and wellness, but whose?” Well, not yours, that's for sure. This month RFK Jr. plans to announce which of the four humors is responsible for autism, but Bob is definitely certain that most children could use at least a little letting. Meanwhile, Donald K. Trump is dead, he just doesn't know it yet because he hasn't seen it on TV. It turns out that when Donald was seen doing his “Stanky Leg” in public, it wasn't all about his stanky leg... It might have been even worse, if you can imagine that. By the way, Trump will only die when the majority of MAGA says he has, so look for that in maybe in a few generations. Sadly, for Donald, the Nobel Committee only hands out their prize on the 10th war averted, and it doesn't seem that Vlad will be punching his ticket on that. Xi Jinping sends a message to Trump, the message that he just doesn't know how to throw a cool parade. Jeffreeeeey Epsteiiiiiiin! Trump sends the US vuvuzela corps over to the capital today, but if that's not enough he can always blow up some more boatloads of Venezuelan citizens. Are you doing your part? ICE agents across the nation sure are doing theirs, and most are getting away with it, as long as they hide their identities a little. Trump will take over Chicago, NYC, and Greenland as soon as he gets rid of that TACO creeping up his spine. Gov. Kathy Hochul is getting used to defying Trump and accepting Zohran Mamdani. The Fifth Circuit rejects Trump's wartime deportation baloney, while Jeanine Pirro dejectedly sucks down another wine box as grand juries award her yet another “no bill prize”. The USDA is cutting farmers loose from more supervision, while oyster farmer Graham Platner fights the oligarchy.  Space Command moves to Alabama, which is more proof that we are in the wrong timeline.

Can You Communicate Without Defensiveness? The Incredible Lesson of Shimon Hamsoni and Rabbe AkivaThis class was presented on Tuesday, 11 Av, 5785, August 5, 2025, Parshas Vaeschanan, at The Barn in Montebello, NY. There is a story in the Talmud, in which Shimon the Imsonite retracts his entire theory that the term "Es" indicates the inclusion of another person or item, due to a single verse in this week’s portion, “You shall fear -- Es -- the Lord your G-d.” How can we be in awe of anybody but G-d? Yet his student, Rabbi Akiva, rescues his teacher’s refuted theory. The obvious question is what did Rabbi Akiva discover which Shimon did not? Shimon could not entertain the notion of including anything in the commandment to fear G-d. For him, such a proposition would be blasphemy. Why did Rabbi Akiva, then, not have a problem of adding Torah scholars to the mitzvah of fearing G-d? How is it that for what Shimon was blasphemy was for Rabbi Akiva perfectly acceptable, and even a mitzvah?! You were selected to win the Nobel Prize for your contribution to physics. You received your tickets to Norway to attend the lavish ceremony. You were featured on the cover of Time magazine, and have been interviewed by hundreds of journals and networks. Minutes after you received the call that the Nobel Committee had chosen you from 40 possible candidates, you went from being an anonymous physicist spending the last 45 years in a laboratory to becoming a world-class scientist whose name will be immortalized in the annals of scientific innovation and discovery. You become a household name. The world is buzzing with your praise. And then… the unthinkable happens. Hours before you go to the airport to fly to Norway, you discover a subtle mistake in one of your 20,000 equations. It is a mistake that no eye has perceived and perhaps will not be perceived for many years. But it is a mistake. Your calculation is erroneous. You have refuted your discovery. You now have a choice to make. Will you allow the “small truth” to destroy your eternal glory? What would you do? It is such a story that the Talmud is addressing. If only we can internalize this type of integrity our lives can be transformed.View Source Sheets: https://portal.theyeshiva.net/api/source-sheets/9744

Norwegian Nobel Committee chair Jorgen Frydnes delivered a speech at Sophia University in Tokyo on Sunday, highlighting the need to listen to the voices of hibakusha, who survived the 1945 atomic bombings of Hiroshima and Nagasaki.

Norwegian Nobel Committee chair Jorgen Frydnes has visited Hiroshima and called for attention to be paid to the voices of hibakusha, who survived the 1945 atomic bombing of the western Japan city.

This week on The Sound Kitchen, you'll hear the answer to the question about Mario Vargo Llosa. There's The Sound Kitchen mailbag, the “The Listener's Corner” with Paul Myers, and Erwan Rome's “Music from Erwan”. All that, and the new quiz and bonus questions too, so click the “Play” button above and enjoy!    Hello everyone! Welcome to The Sound Kitchen weekly podcast, published every Saturday – here on our website, or wherever you get your podcasts. You'll hear the winners' names announced and the week's quiz question, along with all the other ingredients you've grown accustomed to: your letters and essays, “On This Day”, quirky facts and news, interviews, and great music … so be sure and listen every week.Erwan and I are busy cooking up special shows with your music requests, so get them in! Send your music requests to thesoundkitchen@rfi.fr Tell us why you like the piece of music, too – it makes it more interesting for us all!Facebook: Be sure to send your photos to thesoundkitchen@rfi.fr for the RFI English Listeners Forum banner!More tech news: Did you know we have a YouTube channel? Just go to YouTube and write “RFI English” in the search bar, and there we are! Be sure to subscribe to see all our videos.Would you like to learn French? RFI is here to help you!Our website “Le Français facile avec RFI” has news broadcasts in slow, simple French, as well as bilingual radio dramas (with real actors!) and exercises to practice what you have heard.Go to our website and get started! At the top of the page, click on “Test level” and you'll be counselled to the best-suited activities for your level.Do not give up! As Lidwien van Dixhoorn, the head of “Le Français facile” service, told me: “Bathe your ears in the sound of the language, and eventually, you'll get it.” She should know – Lidwien is Dutch and came to France hardly able to say “bonjour” and now she heads this key RFI department – so stick with it!Be sure you check out our wonderful podcasts!In addition to the news articles on our site, with in-depth analysis of current affairs in France and across the globe, we have several podcasts that will leave you hungry for more.There's Spotlight on France, Spotlight on Africa, The International Report, and of course, The Sound Kitchen. We also have an award-winning bilingual series – an old-time radio show, with actors (!) to help you learn French, called Les voisins du 12 bis. Remember, podcasts are radio, too! As you see, sound is still quite present in the RFI English service. Please keep checking our website for updates on the latest from our journalists. You never know what we'll surprise you with!To listen to our podcasts from your PC, go to our website; you'll see “Podcasts” at the top of the page. You can either listen directly or subscribe and receive them directly on your mobile phone.To listen to our podcasts from your mobile phone, slide through the tabs just under the lead article (the first tab is “Headline News”) until you see “Podcasts”, and choose your show. Teachers take note! I save postcards and stamps from all over the world to send to you for your students. If you would like stamps and postcards for your students, just write and let me know. The address is english.service@rfi.fr  If you would like to donate stamps and postcards, feel free! Our address is listed below. Another idea for your students: Brother Gerald Muller, my beloved music teacher from St. Edward's University in Austin, Texas, has been writing books for young adults in his retirement – and they are free! There is a volume of biographies of painters and musicians called Gentle Giants, and an excellent biography of Dr. Martin Luther King, Jr., too. They are also a good way to help you improve your English - that's how I worked on my French, reading books that were meant for young readers – and I guarantee you, it's a good method for improving your language skills. To get Brother Gerald's free books, click here.Independent RFI English Clubs: Be sure to always include Audrey Iattoni (audrey.iattoni@rfi.fr) from our Listener Relations department in your RFI Club correspondence. Remember to copy me (thesoundkitchen@rfi.fr) when you write to her so that I know what is going on, too. N.B.: You do not need to send her your quiz answers! Email overload!This week's quiz: On 19 April, I asked you a question about Mario Vargas Llosa, a Nobel Prize-winning author from Peru. You were to re-read Paul Myers' article “Nobel prize-winning author Mario Vargas Llosa dies aged 89”, and send in the answers to these questions: In which year did Llosa win the Nobel Prize for Literature, and what did the Nobel Committee write about his work?The answer is, to quote Paul's article: “His Nobel Prize in 2010 came 51 years after The Cubs and Other Stories. The Nobel committee said the accolade was an award for his cartography of structures of power and his trenchant images of the individual's resistance, revolt, and defeat.”In addition to the quiz question, there was the bonus question, “What are the obstacles that impede your happiness?”, which was an idea from Erwan Rome, who suggested we look at the philosophy questions asked on the French baccalaureate exams, the French leaving-school exam. This one was for the 2018 students.Do you have a bonus question idea? Send it to us! The winners are: RFI Listeners Club member Father Stephen Wara from Bamenda, Cameroon. Father Steve is also the winner of this week's bonus question. Congratulations, Father Stephen,on your double win.Also on the list of lucky winners this week are RFI Listeners Club members Samir Mukhopadhyay from West Bengal, India - who noted Vargas is one of his favorite Latin American writers; Mahfuzur Rahman from Cumilla, Bangladesh; Niyar Talukdar from Maharashtra, India, and last but not least, RFI English listener Tanjim Tatini from Munshiganj, Bangladesh.Congratulations, winners!Here's the music you heard on this week's programme:  “En route à Bengal” inspired by traditional Bengali folk music, arranged and performed by the Hamelin Instrumental Band; Traditional Peruvian Cumbia; “The Flight of the Bumblebee” by Nicolai Rimsky-Korsakov; “The Cakewalk” from Children's Corner by Claude Debussy, performed by the composer, and “The Loud Minority” by Frank Foster, performed by the the Loud Minority Big Band.Do you have a music request? Send it to thesoundkitchen@rfi.frThis week's question ... you must listen to the show to participate. After you've listened to the show, re-read Ollia Horton's article “Ukraine, Gaza and #MeToo in the spotlight as Cannes Film Festival opens”, which will help you with the answer.You have until 16 June to enter this week's quiz; the winners will be announced on the 21 June podcast. When you enter, be sure to send your postal address with your answer, and if you have one, your RFI Listeners Club membership number.Send your answers to:english.service@rfi.frorSusan OwensbyRFI – The Sound Kitchen80, rue Camille Desmoulins92130 Issy-les-MoulineauxFranceClick here to learn how to win a special Sound Kitchen prize.Click here to find out how you can become a member of the RFI Listeners Club, or form your own official RFI Club.   

We welcome back KJ Noh for two discussions. First, we talk about Han Kang who won the Nobel Prize for Literature, and why this reflects the Nobel Committee's only chance to comment on the genocide in Gaza. Then we turn to the chaos that is going on in South Korea with the President calling for Marshall Law, the legislature rejecting that, and the hundreds of thousands of protestors taking to the streets. There is more here than our press and our government would like to admit. We finish with the song the protestors sing during the protests.

Piezo touch and pressure-sensing ion channels are showing up everywhere as the explanation for physiologic phenomena, both at the macro and micro levels. Ardem Patapoutian, my friend and colleague at Scripps Research, discovered these receptors back in 2010 and was awarded the Nobel Prize in 2021 for his work. As you'll see/hear from our conversation, the field has exploded. And you'll get to know Ardem, who is such a fun, charismatic, and down-to-earth person. He also recently got a unique tattoo (videos below) and I wonder (unlikely) if any other Nobel laureates have one related to their discovery?!Below is a video clip from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The current one is here. If you like the YouTube format, please subscribe! The audios are also available on Apple and Spotify.Transcript with links to audioEric Topol (00:07):Well, hello. It's Eric Topol with Ground Truths, and I've really got a special guest today. The first time for the podcast, I've been able to interview a colleague and faculty at Scripps Research, Ardem Patapoutian, who just by the way happens to be the 2021 Nobel Laureate in Physiology or Medicine. So welcome, Ardem. It's so wonderful to have you.Ardem Patapoutian (00:30):Thanks so much, Eric. Looking forward to chatting with you.Eric Topol (00:34):Well, this has been interesting because although I've known you for several years, I didn't research you. I mean, I had to learn about more than I even do. And of course, one of the great sources of that is on the Nobel Prize website where you tell your whole story. It is quite a story and not to review all of it, but I wanted to go back just before you made the call to move to Los Angeles from Beirut, Lebanon and with the scare that you went through at that time, it seemed like that was just extraordinary that you had to live through that.Ardem Patapoutian (01:11):Yeah, so I am of Armenian origin, but I was born in Lebanon and born in 1967, so I was eight years old when the civil war started. So it's a kind of bizarre childhood in the sense that with all the bombs and fighting in Lebanon. So it was tough childhood to have, but it was never personal. It was bombs and such. And so, the event you're talking about is, I happened to be kidnapped while crossing East to West Beirut. They only held me for four or five hours at first asking me questions to see who I am, but I think they pretty soon figured out that I was not a dangerous guy and they ended up letting me go. But before that, that incident really had a huge impact on me so that by the time I got home, I literally said, I'm out of here. I'm going to find a way to leave the country. And so, that's what, very quickly within a few months I packed and came to United States.Eric Topol (02:19):And how did you pick LA to be your destination?Ardem Patapoutian (02:22):Being from the Armenian community, there's a lot of Armenians in Los Angeles. My cousins already had moved there. They also grew up in Lebanon. And my brother, who's a few years older than me, got admitted to USC graduate school in engineering. So he was going to be there. So it made a lot of sense.Eric Topol (02:44):Oh yeah.Ardem Patapoutian (02:45):Unlike him, I came with no school or job prospects because it happened so fast that I kind of just left. One year I was at American University of Beirut for one year, but then just left and came here. So worked for a year in various jobs and then started going back to school to UCLA.Eric Topol (03:07):Yeah, I saw how there was about a year where you were delivering pizzas and before you got into UCLA, and that must have been an interesting off year, if you will. Well, the story of course, just to fast forward, you did your baccalaureate at UCLA, your PhD at Caltech, postdoc at UCSF, and then you came to Scripps Research 24 years ago along with Pete Schultz, and it's been quite an amazing run that you've had. Now, before we get into PIEZO receptors, the background, maybe you could help me understand, the precursor work seems to be all related to the transient receptor potential (TRP) series, also ion channels. They were of course related to whether it was heat and temperature or somatosensory. How do these channels compare to the ones that you discovered years later?Background on these Ion ChannelsArdem Patapoutian (04:09):Yeah, so the somatosensory neurons that innervate your fingertips and everywhere else in your body, their main job is to sense temperature and pressure. And this is very different than any other neuron or any other cell. So when you touch a hot stove that's burning hot, you need to know about that immediately within milliseconds or something cold. So the opposite side of it is pressure sensing, and it also comes in light touch, which is pleasant or a hammer hitting your finger, which is unpleasant. But all of these have the same characteristic anyway, that is your body has learned at the molecular level to translate a physical stimulus such as temperature and pressure into an electrical signal that neurons use to communicate with each other. But this idea of how you translate physical stimuli into chemical or electrical signal has been a long open question because as you know, most of our cells communicate by chemicals, whether that's hormones or small molecules, we know how that works, receptor bind to ligand, confirmational change and you get a kinase activation and that's enough. But here, how do you sense pressure? How do you sense temperature? It was just, there wasn't much known about that. And that's why our earlier work on TRP channels, which were temperature sensors came before the pressure. And so, they're very related in that sense.Eric Topol (05:52):The structure of these, if you were to look at them, do they look pretty similar? What the TRP as you say, and what you did back in the 2010 Science paper, which we'll link to, of course the classic paper where you describe PIEZO1 and PIEZO2, but if you were to look at this structures, would they look pretty similar?Ardem Patapoutian (06:14):No, that's a good question. And they absolutely don't. That's why finding these receptors were so hard. So if you go back to other sensory receptors, vision rhodopsin G-protein coupled receptor (GPCRs), larger G-protein coupled receptor look the same. So for example, when it was identified by chemically, that smell also works through G-protein coupled receptor. Richard Axel and Linda Buck, who also won the Nobel Prize, found those receptors by homology to visual GPCRs. The ion channels other than the fact that they crossed the membrane a few times or more, they have nothing else in common. If you looked at their structure, you can't even immediately tell they're ion channels. So you couldn't find these by structural homology or sequence homology. So you had to do something else. And usually that means functional screens and et cetera.Eric Topol (07:09):Well, yeah, and I'm in touch with the screening. We'll get to that and how you dig these up and find them. But the somatosensory ones are really interesting because I don't think a lot of people realize that when you have wasabi or you have Listerine mouthwash and feel the burn and that these are all mediated through these channels, right?Ardem Patapoutian (07:35):Yeah. So there's this whole field of chemesthesis, which means senses in your mouth, for example, that are not explained by taste transduction and olfactory. And these are actually by the same somatosensory neurons that help you sense temperature and pressure. And some of these receptors are the same. Their evolution has taken over and used them for many different things. The prime example of this is the capsaicin receptor that David Julius my co-laureate identified, which is also heat receptors. So all languages describe chili peppers as hot, and that's not a coincidence. It actually activates heat activated channel, and that's why we think of it as hot. And so, the same goes to another one of these TRP channels that you mentioned, which is TRPA1, and this one is also activated, but a lot of spicy foods other than the chili pepper active ingredient includes what's in garlic and onions and everything that has this burning sensation and chemicals of this and wasabi and chemicals of this are used in over the counter products like Listerine that cause that burning sensation.Eric Topol (08:54):So when you're chopping onions and it makes you cry, is that all part of it as well?Ardem Patapoutian (08:59):That's all TRPA1, yeah.The Discovery, A Test of PerseveranceEric Topol (09:01):It's wild. Now, this was the groundwork. There were these heat temperature and somatic sensory, and then you were starting to wonder what about touch, what about out pressure and proprioception. And so, you went on a hunt, and it's actually kind of an incredible story about how you were able to find out of these cells that you had, screening hundreds or I guess you got to 72 different small interfering RNA blocking that you finally found the one. Is that right?Ardem Patapoutian (09:37):That's right. So in retrospect, looking back at it, I think there's such an interesting scientific message there. And so, many of us were looking for this touch pressure sensors and we were all looking in the DRG sensory neurons that are complicated heterogeneous, they don't divide. It's not easy to do a screen on them. And ultimately after a lot of failures, what worked for us is to take a step back and ask a much more simpler question. And that was, can we find one of these cell lines that you could easily homogeneously grow in a culture dish, if they respond to mechanical force, can we find our channel there? And then go back and look if it's relevant in vivo for what process. So I think the message is ask the simplest question to answer the question you're after. And finding what that is, is actually the challenge lots of times.Ardem Patapoutian (10:36):But yeah, that's what Bertrand Coste in my lab did is found a simple cell line that neuroscientists had been using for a hundred years and somehow found that they over overexpressed this channel because you can record from them, you can push them and record the currents from them. And then it became a simpler question of finding it. It still took a whole year. He made a list and one by one knocking them out and looking at it. And finally, as you say, number 72 was the hit. When he knocked that out, the current was gone. And that's where we started believing that we have what we were looking for.Eric Topol (11:12):Were you all ever about ready to give up at that point?Ardem Patapoutian (11:16):Oh yeah. I mean that's another lesson. These are postdocs doing the work, right? And they're here three, four years and this was coming close to end of two years, and he didn't have anything yet. So we started talking about having a backup project and he started that and we said, okay, we were ordering this oligos 30 at a time because they're expensive. And so, the first 30 nothing, the second 30 nothing. And how many more are we going to do before we potentially give up? And we said, well, let's do at least a third and then decide, thank goodness it was in that last set.Eric Topol (11:54):Wow, that is so wild. Now what's happened since this discovery, which I guess when you published it in 2010, so it means 14 years ago, but we're on this exponential growth of learning that these piezo receptors are everywhere. They're doing everything. In fact, I recently put on Bluesky, PIEZO ion channels are to human physiology as GLP-1 drugs are to treating many diseases because it's just blowing up. And you've published on some of these of course, on itch and bladder function and vascular function. We'll get to maybe malaria, I mean, but even the cover of Science recently was about wet dog shakes and how animals shake because of water. These receptors are so fundamental to our function. So maybe you could comment, 15 years ago when you were doing the work and you're making this discovery, did you ever envision it was going to blow up like this?Ardem Patapoutian (12:57):Not to this level, but I should have. I think that this idea, again, that most of cell communication is through chemicals is of course a lot of it is true.Ardem Patapoutian (13:12):But it would be ridiculous for evolution to ignore all the physical forces, the pressures that cells experience. And once they do, you would think you would put an instructive way of sensing this pressure signal and using it beneficially to the system or the cell. And so, when we used to talk about pressure sensing at the beginning, there were a couple of touch, pain, maybe proprioception, hearing are like the poster children of pressure sensing. But I think what these molecules, as you say is enabling us is finding out the much more wider role that pressure sensing is playing in physiology and in disease that no one had thought seriously about. And this is, I compare sometimes the finding the PIEZO molecules. You're going in a dark room, and you need to find a door to get into there. And PIEZO is kind of that finding the door once you get in, now you use that molecule now to find physiology instead of the opposite way around. So by pursuing PIEZO expression and function, we're finding all these new roles that they play in physiology and in disease that we didn't think about. And because they're so specialized to sense tension, membrane tension, they don't do anything else. So if you see them expressed somewhere or if you see a function for them, you can bet that they are playing a role in sensing pressure. A lot of biology has kind of come from this hypothesis.Eric Topol (15:00):Well, I mean it is so striking to see the pervasiveness, and I do want to go back just for a second because when you name them PIEZO, you named it after the Greek word. How did you come to that name?Ardem Patapoutian (15:13):So Bertrand and I were actually sitting on Google Translate and we were typing pressure and trying to see what it's like in Greek or in Latin or different languages. His native French and my Armenian and píesi in Greek is pressure. And of course, what's really cool is that the word that more people know about this is piezoelectric device.Eric Topol (15:41):Oh, right.Ardem Patapoutian (15:41):Actually, translates physical force into electricity and vice versa. And in a way, this is a little molecular machine that does the same thing, and he uses this piezoelectric device to actually push on the cell. That's his assay. So it all came together as a very appropriate name for this gene and protein.Call from the Nobel CommitteeEric Topol (16:04):Oh really, it's perfect. And you get to name it, even that's fun too, right? Now we're going to go to getting the call at 2:00 AM, but it didn't come to you because your phone from the Nobel Committee was on ‘do not disturb' and your 94-year-old father, Sarkis. How did the Nobel Committee know to get ahold of him? How did they reach him in the middle of the night?Ardem Patapoutian (16:37):Yeah, so I mean, since receiving it, I've had conversations with various committee members, and they are very resourceful folks, and they have assistants who throughout the year collect information on all potential people who might win. They're also doing last minute searches. So they looked for other Patapoutian's in California. So they just called my dad who initially yelled at them for disturbing him at 2:00 AM.Eric Topol (17:17):And he could get through to you because he was not on your list of ‘do not disturb' or something like that.Ardem Patapoutian (17:22):I didn't even know this. And I don't know if the policy has changed, but in some phones the ‘do not disturb' if it's called by someone who's in your contacts or favorites.Ardem Patapoutian (17:34):After I think they called twice and they get through, and that's how.Getting a Tattoo!Eric Topol (17:39):That's amazing. Wow. Well, that's quite a way to find out that you're getting recognized like this. Now recently you got a tattoo, which I thought was really remarkable, but we're going to put that of course in the post. Tell us about your decision to get the PIEZO channel on your arm.Ardem Patapoutian (18:02):So as you can tell, I'm obsessed about PIEZO and it's been good to me. And I had the idea a while ago, and my very wise wife, Nancy Hong, said that you might be going through midlife crisis. Why don't you wait a year? If you still believe in it, you should do it. And that's what I did. I waited a year, and I was like, I still want to do it. And I guess I could show it. Here it is.Eric Topol (18:32):Oh yeah, there it is. Oh wow.Ardem Patapoutian (18:33):What's cool is that I can pretty much flex to show the activation mechanism because the channel is like bent like this in the plasma membrane. When it's stretched, it opens and it actually flattens like this. So I feel like other than being a tattoo, this is both performance art and instructional device. When I'm giving talks without PowerPoint slides, I could give a demonstration how this ion channel works.[Below is from a presentation that Ardem recently gave, the Harvey Lecture, at Rockefeller University.]Eric Topol (19:04):It's wild. Now how did you find a tattoo artist that could, I mean, it's pretty intricate. I mean, that's not your typical tattoo.Ardem Patapoutian (19:14):Yeah, I put it up on social media that I was thinking of doing this, and many scientists are into tattoos, so I actually got so many recommendations. And one of them was a local here in San Diego, and she is very popular. I waited six months to get this, I was on a waiting list. The appointment was six months off when we made it. So she's very popular and she's very good.Eric Topol (19:45):Was it painful to get that done?Ardem Patapoutian (19:47):Well, that's actually really cool, right? Because PIEZO2 is involved in pain sensation, and I felt it while it was being tattooed on my arm. The whole day, I was there like six and a half hours.New Prospect for Pain MedicationEric Topol (20:00):Oh my gosh. Wow. Now that gets me to pain because, I'd like you to talk a bit about the people that don't have mutations or loss of function PIEZO receptors and also what your thoughts are in the future as to maybe we could develop a lot better pain medications.Ardem Patapoutian (20:22):Yeah, we're working on it. So you're right. One of the great parts of the science story, and this is mainly the work of Alex Chesler and Carsten Bönnemann at the NIH, where they identified people who came to the clinic for undiagnosed conditions, and they were uncoordinated and had difficulty walking. And when they did whole-exome sequencing, they found that they had mutations in PIEZO2, there were loss of function, as you say. So complete loss on both chromosomes. And when they started testing them, they realized that just like we had described them in animal models, humans without PIEZO2 as well, didn't sense touch, don't have proprioception. This sense of where your limbs are, that's so important for balance and most other daily functions that we take it for granted. So they were completely lacking all of those sensations. They also do not feel their bladder filling.Ardem Patapoutian (21:26):And so, they have learned to go on a schedule to make sure they don't have accidents. And many of these projects that we've done in the lab collaboration with Alex Chesler, et cetera, have come from the observations of what else these individuals experience. And so, it's been a great kind of collaboration communication between mechanistic animal model studies and the clinic. And so, one of the things that these individuals don't sense in addition to touch, is something called tactile allodynia, which is simply when touch becomes painful. You and I experienced this after small injury or sunburn where just touching your shoulder becomes painful, but for peripheral neuropathy and other neuropathic pain conditions, this is one of the major complaints that individuals have. And we know from the NIH studies that these individuals don't have this tactile allodynia. So touch becomes painful and doesn't apply to them, which tells us that if we block PIEZO2, we can actually get interesting relief from various aspects relative to neuropathic pain on other pain related neuropathies. But given everything we talked about, Eric, about how this is important for touch and proprioception, you don't want to make a pill that blocks PIEZO2 and you take it because this will have some serious on target side effects. But we are developing new compounds that block PIEZO2 and hope that it might be useful, at least as a topical medication pain and other indications. And we're actively working on this, as I said.Eric Topol (23:15):Yeah, I mean the topical one sounds like a winner because of peripheral neuropathy, but also I wonder if you could somehow target it to sick cells rather than if giving it in a systemic targeted way. I mean it has tremendous potential because we are on a serious hunt for much better relief of pain than exists today.Ardem Patapoutian (23:41):Absolutely.Eric Topol (23:42):Yeah. So that's exciting. I mean, that's another potential outgrowth of all this. Just going back, I mean the one that prompted me in November to write that about the human physiology in PIEZO, it was about intestinal stem cell fate decision and maintenance. I mean, it's just everywhere. But the work you've done certainly now has spurred on so many other groups to go after these different and many unanticipated functions. Were there any ones, of course, you've been pretty systematically addressing these that actually surprised you? You said, oh, are you kidding me when you read this? I never would've guessed this, or pretty much they followed suit as things were moving along.Ardem Patapoutian (24:33):So one of them is this role in macrophages that I found fascinating that we found a few years ago. So again, this came from human studies where PIEZO1 gain-of-function mutations. So in relation to loss of function, their gain-of-function where there's more activity given a certain amount of pressure. They have dehydrated red blood cells, which I'm not going to talk about right now. But they also have shown that in these patients, individuals, it's not really that pathological. They also have age-onset iron overload. What does that have to do with pressure sensing? And we brought that information into animal models, and we found that macrophages, their rate of phagocytosis depends on PIEZO, so that if you have too little PIEZO, they don't phagocytosis as much. If you have too much PIEZO, the phagocytosis too much. And this increased rate of phagocytosis in the long term because it's constantly eating red blood cells and the iron is circulating more causes long-term effects in iron overload. And again, as you kind of set that up, who would've thought that mechanical sensation is important for this basic hematology type?Eric Topol (25:52):Yeah, I mean, because we've been talking about the macro things, and here it is at the cellular level. I mean, it's just wild.Ardem Patapoutian (25:59):If you go back and look at a video of a macrophage eating up red blood cells, then you go, oh, I see how this has to do with pressure sensing because it is like extending little arms, feeling things letting go, going somewhere else. So again, I want to bring it back by this simple cell biological function of a cell type, like macrophage, exploring its environment is not just chemical, but very mechanical as well. And so, in retrospect, it is maybe not that surprising, that pressure sensing is important for its physiology.Career Changing?Eric Topol (26:33):Yeah, that's extraordinary. Well, that gets me to how your life has changed since 2021, because obviously this a big effect, big impact sort of thing. And I know that you're the first Armenian, first person from Lebanon to get this recognition. You recognized by the Lebanese Order of Merit. There's even a stamp of you, your picture characterized in 2022.Eric Topol (27:04):So if you were to sum up how it's changed because I see no change in you. You're the same person that has a great sense of humor. Often the tries to humor relaxed, calming. You haven't changed any to me, but how has it affected you?Ardem Patapoutian (27:26):Thank you, Eric. That's very kind of you. I try very hard for it not to change me. I do get a little bit more attention, a ton more invites, which unfortunately I have to say no to a lot of them because, and I'm sure you're very familiar with that concept and a lot of things are offered to you that I feel like it's so tempting to say yes because they're wonderful opportunities and an honor to be asked. But the end of the day, I'm trying to be very disciplined and not taking things on that I can do as an opportunity. But things that I really want to do. I think that's so hard to do sometimes is to separate those two. Why am I doing this? Is this really important for the goals that I have? So in one way, the answer for that is that I just want to stay in the lab and do my research with my students and postdoc, which is what I enjoy the most. But on the other hand, as you said, being the first Armenian who's received this, literally after the Nobel, I got this whole elementary school, all Armenian kids write to me multiple letters.Ardem Patapoutian (28:39):And they said, you look like me. I didn't think I could do this, but maybe I can. So in a sense, to ignore that and say, no, I just want to do my science, I don't want to be involved in any of that is also wrong. So I'm trying to balance being engaged in science outreach and helping to make science understood by the general public, realize that we're just regular people and at the same time how awesome science is. I love science and I like to project that, but leave plenty of time for me to just be a scientist and be in my lab and interact with my colleagues at Scripps, including you.Immigrant ScientistsEric Topol (29:21):Well, we're so lucky to have that chance. And I do want to mention, because you're prototyping in this regard about great immigrant scientists and other domains of course, but every year the Carnegie Foundation names these great immigrants and one year you were of course recognized. And in recent years, there have been more difficulties in people wanting to come to the US to get into science, and they wind up going to other places. It seems like that's a big loss for us. I mean, what if we weren't able to have had you come and so many hundreds, thousands of others that have contributed to this life science community? Maybe you could comment about that.Ardem Patapoutian (30:10):Yeah, I think it is tragic, as you say. I think in some circles, immigrants have this negative image or idea of what they bring, but at every level, immigrants have contributed so much to this country. It's a country of immigrants, of course, to start with. And I think it is important to put up a positive image of immigration and science is the ultimate example of that, right? I mean, I think when you go into any laboratory, you probably find if there's a lab of 16 people, you probably find people from 10 different countries. And we all work together. And the idea of also immigrant and especially about science is that I'm a big believer of changing field, changing things because just like that, immigrants have changed their whole life. So they come to a new culture, they bring with them their own way of thinking and their way of seeing things. And then you come into a new environment, and you see it a little bit differently. So that kind of change, whether it's because of physical immigration or immigrating from one field to another in science is really beneficial for science and society. And I think positive examples of this are an important part of highlighting this.Eric Topol (31:40):I couldn't agree with you more really.Bluesky vs Twitter/XEric Topol (31:41):Now, speaking of migration, there's been recently a big migration out of X, formerly Twitter to Bluesky, which I like the metaphor you liken to the Serengeti. Can you tell us about, now I know you're posting on Bluesky and of course so many others that you and I are mutual contacts, and our different networks are. What do you think about this migration outside of what was the platform where a lot of this, we shared things on X or before Musk took over known as Twitter? Thoughts about Bluesky?Ardem Patapoutian (32:27):Yeah, I think I use social media for a few reasons. The number one reason should be is to see new science by colleagues. My main point is that, but also, again, having fun in science is a big part of my draw to this. And as you can see from my posts, it's a bit lighthearted, and that's really me.Eric Topol (32:52):Right. Yeah.Ardem Patapoutian (32:52):I think on Twitter, things start getting a little bit dark and too many negative comments, and it was just not productive. And I just felt like after the elections, I felt like it was time to migrate. And I find Bluesky a great scientific community, and it's remarkable how quickly people have migrated from Twitter to Bluesky. But the counter argument for this is that you should stay in a place where majority of people are, because being in a bubble surrounding yourself by people like you doesn't help society. And so, I get that perspective as well. It just depends on what you're using the platform for and it's a difficult issue. But yeah, I've taken a break probably long-term break from Twitter. I'm on Bluesky now.Eric Topol (33:48):Yeah, no, the point you're bringing up about the echo chamber and is there going to be one for people that are leaning one way and they're thinking, and another with a whole different, often politically charged and even extreme views? It's really unfortunate if it does wind up that way. But right now, it seems like that migration is ongoing and it's substantial. And I guess we'll see how it settles out. I share your concern, and so far, I've been trying to keep a foot in both areas because I think if we all were to leave, then we're just kind of caving into a, it's tricky though. It really is because the noxious toxic type of comments, even when you try to avoid comments, you say, only followers can make a comment, they'll of course, quote your thing and then try to ding you and whatever. It's just crazy stuff, really.Ardem Patapoutian (34:53):I mean, what I think is that, that's why I said depends on why. I mean, your presence on social media is such an important part of science education. And I could almost say you can't afford to do what I do, which is I'm just putting my goofy posts and having fun. So we have different purposes in a way, and yeah, that affects what you use and how you use it.Eric Topol (35:17):Yeah, no, it's tricky it really is. We covered a lot of ground. Is there anything I missed that you want to get out there? Any part of this, your story and the PIEZO story, science and everything else that I didn't bring up?The Essentiality of Basic ScienceArdem Patapoutian (35:42):I just think that the basic science community is really suffering from decreasing amounts of funding and appreciation of doing basic science. And one of my goals, in addition to this immigrant scientist thing, is to remind people that all medicines start with basic science work. And funding this has mainly been through NIH and it's getting harder and harder for basic scientists to secure funding and I'm really worried about this. And we need to find ways to be okay for people to do basic science. And I'll give you one example. Whenever we make a publication and there's a journalist talking to us or some kind of press coverage, they ask, how is this directly affecting patients? And my work actually is very much related to patients, and I answer that question, but I also say, but it's also important to do science for the science sake because you don't know where the applications are going to come from. And we need to, as a society, encourage and fund and support basic science as the seeds of all these translational work. And I think doing that just kind of highlights that this is important too. We should support it, not just things that right now seem very related to translational that directly helps patients.Eric Topol (37:16):Well, I'm so glad you emphasized that because I mean, the PIEZO story is the exemplar. Look what's come of it, what might still come of it. In many respects here you are maybe 15 years into the story and there's still many parts of this that are untold, but if it wasn't for the basic science, we wouldn't have these remarkable and diverse insights. And recently you cited, and I think so many people read about the ‘crown jewel' NIH, front page New York Times, and how it's under threat because the new NIH director doesn't have a regard for basic science. He's actually, he's confirmed, which is likely, he's an economist, physician economist, never practiced medicine, but he doesn't really have a lot of regard for basic science. But as you point out, almost every drug that we have today came out of NIH basic work. And I mean, not just that, but all the disease insights and treatments and so much.Eric Topol (38:25):So this is really unfortunate if we have not just an NIH and other supporting foundations that don't see the priority, the fundamental aspect of basic science to then lead to, as we call translational, and then ultimately the way to promote human health, which is I think what we're all very much focused on ultimately. But you can't do it without getting to first base, and that's what you have done. You served it up and it's a great example. Well, Ardem, it's always a pleasure. This is a first time talking through a podcast. I hope we'll have many, many visits informally that will complement the ones we've already had, and we will follow the PIEZO work. Obviously, you have had just an exceptional impact, but you're still young and who knows what's next, right? I mean, look what happened to Barry Sharpless. He won here. He won two Nobel prizes, so you never know where things are headed.Ardem Patapoutian (39:36):Thank you, Eric, and I really appreciate what you do for the biomedical community. I think it's wonderful through your social media and this podcast, we all appreciate it.***********************************************************************************Please take a moment to complete the poll above.Thank you for reading, listening and subscribing to Ground Truths.If you found this informative please share it!All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and of course appreciated. All proceeds from them go to support Scripps Research. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. I welcome all comments from paid subscribers and will do my best to respond to each of them and any questions.Thanks to my producer Jessica Nguyen and to Sinjun Balabanoff for audio and video support at Scripps Research.And Happy New Year! Get full access to Ground Truths at erictopol.substack.com/subscribe

When the phone rang 10 years ago while Norwegian neuroscientist May-Britt Moser was in a particularly engaging lab meeting, she almost didn't answer it.Good thing she did! It was Göran Hansson, secretary of the Nobel Committee for Physiology or Medicine, with the news: May-Britt Moser and Edvard Moser, along with their mentor and colleague John O'Keefe from the University College London, had just won the Nobel Prize in Physiology or Medicine for their discoveries of two types of brain cells that work together to function like a GPS in the brain.That system allows animals -including us - to know where they are, and navigate to where they want to go. This was a groundbreaking discovery because it gave us critical insight into how an area of the brain, far from the normal sensory inputs of sight, sound and touch, constructs its own way of understanding space. And, because this same area of the brain, and our ability to navigate, are affected early on in Alzheimer's patients, it offers an inroad for clinicians studying the disease. In fact, the KG Jebsen Centre for Alzheimer's Disease, a part of the Mosers' Kavli Institute, is working to bring these fundamental insights about the brain to clinical practice. This episode is a celebration of the 10th anniversary of the Nobel award. To make it, I cracked open a time capsule of sorts: When the Mosers first learned that they had won the scientific world's highest honour, I ran down to their lab and recorded everything! The files in this podcast are from that day and the heady days afterwards.My guests on today's episode are May-Britt Moser and Edvard Moser.You can also find lots more material, including videos, more popular science articles and background information on this webpage. And don't forget to subscribe to 63 Degrees North to hear my second podcast, coming in early 2025, about the most recent findings from the Mosers' lab – and a look into the future. Hosted on Acast. See acast.com/privacy for more information.

12 October, the day after the announcement of the 2024 Nobel Peace Prize, we invited Jørgen Watne Frydnes, Chair of the Norwegian Nobel Committee to give a short lecture on awarding the prize to Nihon Hidankyo. Read more about the Japanese organisation Nihon Hidankyo here: https://peaceprizelaureates.nobelpeacecenter.org/en/laureate/2024-nihon-hidankyo

The Nobel Peace Prize has been awarded to a Japanese grassroots movement working to eliminate nuclear weapons. It's made up of survivors of the Hiroshima and Nagasaki atomic bombings. The group's leader says he felt people helping Palestinians in Gaza deserved to win instead. So, what's behind the Nobel Committee's decision? In this episode: Asmund Aukrust, Member of Parliament, Norway's Labour Party.  Lex Takkenberg, Senior Advisor, Arab Renaissance for Democracy and Development.   Henrik Urdal, Director, Peace Research Institute Oslo. Host: Tom McRae Connect with us:@AJEPodcasts on Twitter, Instagram, Facebook At Al Jazeera Podcasts, we want to hear from you, our listeners. So, please head to https://www.aljazeera.com/survey and tell us your thoughts about this show and other Al Jazeera podcasts. It only takes a few minutes!

On the day the Nobel Committee awards the Peace Prize, Gideon Rose, adjunct senior fellow at the Council on Foreign Relations (CFR), the former editor of Foreign Affairs and author of How Wars End (Simon & Schuster, 2010), looks at this year's recipient and back through its impact over the last century, as part of our ongoing centennial series.

This year's Nobel Peace Prize winner is a Japanese organization working toward global nuclear disarmament.On Today's Show:On the day the Nobel Committee awards the Peace Prize, Gideon Rose, adjunct senior fellow at the Council on Foreign Relations (CFR), the former editor of Foreign Affairs and author of How Wars End (Simon & Schuster, 2010), looks at this year's recipient and back through its impact over the last century, as part of our ongoing centennial series.

*) Israel orders Beirut residents to leave before air strikes The Israeli military has issued an urgent warning for residents in southern Beirut to evacuate ahead of planned air strikes, which it claims are targeting Hezbollah-linked sites as Tel Aviv widens its war throughout the Middle East. According to the Lebanese Health Ministry over 2,100 Lebanese people have been killed and thousands have been wounded since the Israeli attacks began. Meanwhile, Tel Aviv's ally, the US' trust in Israeli Prime Minister Netanyahu's government is eroding, with concerns over Israel's handling of Gaza and rejection of a ceasefire proposal, according to a report published by Axios. US officials have said they are concerned that the directive is setting the stage for a potential siege and that Palestinian civilians would not be allowed to return. *) WHO warns of disease outbreaks in Lebanese shelters amid Israel's invasion The World Health Organization warns of looming disease outbreaks in Lebanon as crowded shelters and hospital closures strain the health system amid Israel's intensified ground invasion. The UN health agency has already warned that the system is overstretched and five hospitals in the country have closed so far and four are only partly functional. Meanwhile, the WFP highlighted Lebanon's food crisis, with abandoned farmland and rotting crops threatening food security in the conflict zone. *) India's Modi surprises with Haryana win as opposition alliance takes Kashmir Indian PM Narendra Modi's BJP clinched a surprise win in Haryana state, defying exit polls and reinforcing its strength despite recent national setbacks. The Congress party, predicted to win, called the outcome "unexpected" and plans to challenge the results. Meanwhile, National Conference, a regional Kashmiri opposition alliance won in India-administered Kashmir, signalling shifting dynamics ahead of key state elections. *) British spy chief reveals surge in youth involvement in extremism UK's MI5 Chief Ken McCallum warns of a surge in youth terrorism cases, with under-18s now making up 13 percent of investigations—a threefold rise in three years. He cites online extremism, driven by right-wing ideologies, as a key factor. McCallum said the intelligence service was seeing "far too many cases where very young people are being drawn into poisonous online extremism" and singled out "canny" internet memes. *) AI pioneers Geoffrey Hinton and John Hopfield receive Nobel honours Geoffrey Hinton, the "Godfather of AI," and physicist John Hopfield won the Nobel Physics Prize for groundbreaking AI foundations. Hinton, 76, expressed concern over AI's future dominance, despite its benefits. The Nobel Committee highlighted AI's daily impact, urging ethical use. Hopfield, 91, was honoured for his "Hopfield network," crucial for image and pattern recognition.

“I heard what sounded like an authentic call from the Nobel Committee!” New medicine laureate Gary Ruvkun might have received a prank call or two in the past, but today's was genuine. He talked to the Nobel Prize's Adam Smith minutes after hearing the news, about the pleasure of finding things out, the electrifying growth of the microRNA field over the years, and the benefits of taking time out. And as for what's about to follow: “It's going to be a fun ride!” Hosted on Acast. See acast.com/privacy for more information.

Chris and Doran are joined by Christopher Feran to discuss, "Effects of coffee roasting technologies on cup quality and bioactive compounds of specialty coffee beans", appearing in Food Sci. Nutr., 2020, 8, 6120. This paper has some major issues — I hope you enjoy us diplomatically deconstructing it. The article can be found here: ⁠https://doi.org/10.1002/fsn3.1904 About Christopher: Despite having recently opened his own roastery, Aviary, based in Ohio, Christopher finds time to be a leading consultant in the specialty coffee industry. He has a wealth of knowledge and shares some of it today, discussing sample roasting. Introduction preamble: The Nobel Committee.

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Rapid capability gain around supergenius level seems probable even without intelligence needing to improve intelligence, published by Towards Keeperhood on May 6, 2024 on LessWrong. TLDR: 1. Around Einstein-level, relatively small changes in intelligence can lead to large changes in what one is capable to accomplish. 1. E.g. Einstein was a bit better than the other best physi at seeing deep connections and reasoning, but was able to accomplish much more in terms of impressive scientific output. 2. There are architectures where small changes can have significant effects on intelligence. 1. E.g. small changes in human-brain-hyperparameters: Einstein's brain didn't need to be trained on 3x the compute than normal physics professors for him to become much better at forming deep understanding, even without intelligence improving intelligence. Einstein and the heavytail of human intelligence 1905 is often described as the "annus mirabilis" of Albert Einstein. He founded quantum physics by postulating the existence of (light) quanta, explained Brownian motion, introduced the special relativity theory and derived E=mc from it. All of this. In one year. While having a full-time job in the Swiss patent office. With the exception of John von Neumann, we'd say those discoveries alone seem more than any other scientist of the 20th century achieved in their lifetime (though it's debatable). Though perhaps even more impressive is that Einstein was able to derive general relativity. Einstein was often so far ahead of his time that even years after he published his theories the majority of physicists rejected them because they couldn't understand them, sometimes even though there was experimental evidence favoring Einstein's theories. After solving the greatest open physics problems at the time in 1905, he continued working in the patent office until 1908, since the universities were too slow on the uptake to hire him earlier. Example for how far ahead of his time Einstein was: Deriving the theory of light quanta The following section is based on parts of the 8th chapter of "Surfaces and Essences" by Douglas Hofstadter. For an analysis of some of Einstein's discoveries, which show how far ahead of his time he was, I can recommend reading it. At the time, one of the biggest problems in physics was the "Blackbody spectrum", which describes the spectrum of electromagnetic wavelengths emitted by a Blackbody. The problem with it was that the emitted spectrum was not explainable by known physics. Einstein achieved a breakthrough by considering light not just as a wave, but also as light quanta. Although this idea sufficiently explained the Blackbody spectrum, physicists (at least almost) unanimously rejected it. The fight between the "light is corpuscles" and "light is a wave" faction had been decided a century ago, with a clear victory for the "wave" faction. Being aware of these possible doubts, Einstein proposed three experiments to prove his idea, one of which was the photoelectric effect. In the following years, Robert Millikan carried out various experiments on the photoelectric effect, which all confirmed Einstein's predictions. Still, Millikan insisted that the light-quanta theory had no theoretical basis and even falsely claimed that Einstein himself did not believe in his idea anymore. From Surfaces and Essences (p.611): To add insult to injury, although the 1921 Nobel Prize in Physics was awarded to Albert Einstein, it was not for his theory of light quanta but "for his discovery of the law of the photoelectric effect". Weirdly, in the citation there was no mention of the ideas behind that law, since no one on the Nobel Committee (or in all of physics) believed in them! [1][...] And thus Albert Einstein's revolutionary ideas on the nature of light, that most fundamental and all-...

rWotD Episode 2483: Gerhard Ertl Welcome to random Wiki of the Day where we read the summary of a random Wikipedia page every day.The random article for Tuesday, 20 February 2024 is Gerhard Ertl.Gerhard Ertl (German pronunciation: [ˈɡeːɐ̯haʁt ˈɛʁtl̩] ; born 10 October 1936) is a German physicist and a Professor emeritus at the Department of Physical Chemistry, Fritz-Haber-Institut der Max-Planck-Gesellschaft in Berlin, Germany. Ertl's research laid the foundation of modern surface chemistry, which has helped explain how fuel cells produce energy without pollution, how catalytic converters clean up car exhausts and even why iron rusts, the Royal Swedish Academy of Sciences said.His work has paved the way for development of cleaner energy sources and will guide the development of fuel cells, said Astrid Graslund, secretary of the Nobel Committee for Chemistry.He was awarded the 2007 Nobel Prize in Chemistry for his studies of chemical processes on solid surfaces. The Nobel academy said Ertl provided a detailed description of how chemical reactions take place on surfaces. His findings applied in both academic studies and industrial development, the academy said. “Surface chemistry can even explain the destruction of the ozone layer, as vital steps in the reaction actually take place on the surfaces of small crystals of ice in the stratosphere,” the award citation reads.In 2015, Ertl signed the Mainau Declaration 2015 on Climate Change on the final day of the 65th Lindau Nobel Laureate Meeting. The declaration was signed by a total of 76 Nobel Laureates and handed to then-President of the French Republic, François Hollande, as part of the COP21 climate summit in Paris.This recording reflects the Wikipedia text as of 00:48 UTC on Tuesday, 20 February 2024.For the full current version of the article, see Gerhard Ertl on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm Danielle Neural.

Free, ungated access to all 265+ episodes of “It's 5:05!” on your favorite podcast platforms: https://bit.ly/505-updates. You're welcome to

It's that time of year when an economist is woken by an early call from the Nobel Committee in Sweden. This year, it was the turn of Claudia Goldin, whose work has revolutionised our understanding of gender in the labour market. And on this week's podcast, we speak to her.Hosts: Mike Bird, Alice Fulwood and Tom Lee-Devlin. Guests: Arjun Ramani, from The Economist; and Claudia Goldin.Sign up for Economist Podcasts+ now and get 50% off your subscription with our limited time offer. You will not be charged until Economist Podcasts+ launches.If you're already a subscriber to The Economist, you'll have full access to all our shows as part of your subscription.For more information about Economist Podcasts+, including how to get access, please visit our FAQs page. Hosted on Acast. See acast.com/privacy for more information.

It's that time of year when an economist is woken by an early call from the Nobel Committee in Sweden. This year, it was the turn of Claudia Goldin, whose work has revolutionised our understanding of gender in the labour market. And on this week's podcast, we speak to her.Hosts: Mike Bird, Alice Fulwood and Tom Lee-Devlin. Guests: Arjun Ramani, from The Economist; and Claudia Goldin.Sign up for Economist Podcasts+ now and get 50% off your subscription with our limited time offer. You will not be charged until Economist Podcasts+ launches.If you're already a subscriber to The Economist, you'll have full access to all our shows as part of your subscription.For more information about Economist Podcasts+, including how to get access, please visit our FAQs page. Hosted on Acast. See acast.com/privacy for more information.

It's Nobel week on the podcast, and reporter Megan Molteni details the unique story of this year's winners for medicine, Katalin Karikó and Drew Weissman. Then, our colleague Jason Mast joins us to explain the scientific and ethical quandaries facing the teams attempting to develop HIV vaccines.

Dr Glenn McConell chats with Professor Juleen Zierath who has had a remarkable background with current senior roles at both the Karolinska Institute in Sweden and the University of Copenhagen in Denmark. She was also previously the Chair of the Nobel Committee. We discuss the effects of circadian rhythms on: muscle insulin sensitivity, metabolic responses to exercise in T2D vs controls, exercise performance, metabolism in men vs women and integrative physiology. A very interesting chat. Twitter: @JuleenRZierath. 0:00. Introduction and Juleen's academic and research background 7:39. Ball State University and David “Doc” Costill 9:40. What it's like on the Nobel Prize committee 15:00. Circadian rhythms and physiology/metabolism/exercise 18:50. Metabolic flexibility, circadian biology and exercise 19:50. Central and peripheral clocks etc. 23:55. Jet lag and light/clocks 24:25. Different experimental models: Insects, mice and humans 27:53. Circadian misalignments in obesity and diabetes 29:02. Genetics + environment re obesity, insulin sensitivity 30:06. Circadian rhythms in muscle cells 32:40. Exercise: can it cure type 2 diabetes? 35:32. Genes matter 35:42. Shift work and insulin resistance / cancer 36:46. Hyperglycemia after morning not afternoon exercise (CGMs) 43:50. Mortality and the time of exercise 44:56. Effect of the time of day on exercise performance 46:18. Sex differences: exercise, inflammation and the genome 50:37. Controversies?: we don't know enough/more to learn 53:43. Takeaway messages 56:09. Outro (9 secs) Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise's effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all. The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University. He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9). Connect with Inside Exercise and Glenn McConell at: Twitter: @Inside_exercise and @GlennMcConell1 Instagram: insideexercise Facebook: Glenn McConell LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460 ResearchGate: Glenn McConell Email: glenn.mcconell@gmail.com Subscribe to Inside exercise: Spotify: shorturl.at/tyGHL Apple Podcasts: shorturl.at/oFQRU YouTube: https://www.youtube.com/@insideexercise Anchor: https://anchor.fm/insideexercise Google Podcasts: shorturl.at/bfhHI Anchor: https://anchor.fm/insideexercise Podcast Addict: https://podcastaddict.com/podcast/4025218 Not medical advice

Welcome to December 10, 2022 on the National Day Calendar. Today we celebrate with a toast to Summer and those who change the world.    Lagers are distinguished from other beers by their cold-conditioning process. They are made with “bottom-fermenting” yeast that can develop at colder temperatures. Before the advent of refrigeration, brewers perfected this process in cellars dug into the ground that were filled with ice. The delicious results are often described as “crisp” and “refreshing.” With so many choices from pale, amber or dark to several craft varieties, you will likely add lager to your list of favorite things. On National Lager Day, grab your friends and celebrate the midwinter season with the taste of Summer.   At the age of 17, Alfred Nobel spoke five languages fluently. This was only the beginning of the young man's accomplishments. Through the course of his life, Nobel amassed a fortune from his 87 businesses and 355 patents worldwide, including the patent for dynamite. In his third and last will, Nobel stated that the money should be given away to those who had done their best to benefit mankind. Each annual prize would recognize the fields of physics, chemistry, medicine, literature, and peace. Though it took nearly five years after his passing, the Nobel Committee has awarded these prizes every year since 1901. On Nobel Prize Day, we celebrate the generosity of Alfred Nobel and those who continue to make the world a better place.  I'm Anna Devere and I'm Marlo Anderson. Thanks for joining us as we Celebrate Every Day. Learn more about your ad choices. Visit megaphone.fm/adchoices

Our host, Dr. Fethke, dedicates this episode to a remarkable college classmate and friend at a time when she needs everyone's support. This person is none other than Maria Ressa, the recipient of the 2021 Nobel Peace Prize, recognized for her tireless efforts over the past three decades to champion Freedom of the Press in the face of overwhelming obstacles. In the words of the Nobel Committee, Maria Ressa received the Nobel Peace Prize jointly with Russia's Dmitry Muratov for "their efforts to safeguard freedom of expression, which is a precondition for democracy and lasting peace."In order to do justice to Ressa's cause, Dr. Fethke has invited a very special and highly knowledgeable guest, Professor Kathy Kiely. She is the Lee Hills Chair in Free Press Studies at the Missouri School of Journalism. She has worked more than four decades as a reporter and editor for regional and national newspapers as well as online and multimedia publications. She has been recognized for her passionate support of  transparency, free speech and education. After a long career covering politics in Washington, Kiely moved into the classroom full-time because, she says, universities are the laboratories that will discover the formula for making fact-based journalism viable again. Kiely has covered regional and national politics for a number of news outlets, including USA TODAY, the New York Daily News, the Houston Post, the Arkansas Democrat-Gazette and the Pittsburgh Press. She served as an editor for WAMU, Bill Moyers, the Sunlight Foundation, Bloomberg Politics and helped coordinate the National Journal's campaign coverage with CBS News. She also served on the Congressional Standing Committee of Correspondents and on the boards of the National Press Club Journalism Institute and the Daily Princetonian. She holds a master's degree from American University and a bachelor's degree from Princeton University. She is the inaugural Press Freedom Fellow for the National Press Club‘s nonprofit Journalism Institute.Prof. Kiely is a well recognized advocate of Journalistic Freedom who believes that Maria Ressa's voice is at an extremely high risk of being silenced by those in power in the Philippines who are threatened by the integrity and truth of her work. Kiely has commented that the Nobel Peace Prize given to journalists Maria Ressa and Dmitry Muratov is a warning that across the globe, “forces of darkness and intolerance are on the march… Journalists are the canaries in the mine shaft.In this episode, Prof. Kiely teaches us why Freedom of Speech and Health are intrinsically linked. Dr. Fethke and Prof. Kiely review the rationale behind the U.S. Consititution's 1st Amendment protecting free speech and a free press. She then clearly reviews the evolution of digital and social media, with its pros and cons. She defines the concepts of Misinformation and Disinformation, clarifying why the latter is so dangerous to us all. She explains that the Nobel Committee has specifically recognized Maria Ressa because she has led the way for us all to understand the impact of Disinformation and is actively working on solutions to regain the integrity of facts and bring the truth back to journalism. Kiely stresses that the battles that Maria Ressa and her journalist team at Rappler are fighting in the Philippines are critically relevant to the Global pursuit of democracy. As Kiely reminds us, “My father fought in WW2 to defend and help establish a free Philippines. We must never forget that Maria Ressa's defense of Freedom of the Press is a part of our fathers' legacies. To do so would be a dishonor to their cause and memory.”LINKS:House: https://www.house.gov/Senate: https://www.senate.gov/Post office (where you can look up ZIP+4 to get House member's name: https://www.usps.com/

In today's episode for 12th October 2022, we see why the Nobel Committee awarded the Sveriges Riksbank Prize in Economic Sciences to Bernanke, Diamond and Dybvig.

The winners of this year's Nobel Peace Prize are recognized, the Nobel Committee said, for years of protecting the fundamental rights of citizens in Russia, Ukraine and Belarus.

Who will win this year's Nobel Prize in literature? And what—beyond literary excellence—does the award stand for? On episode 54 of The Politics of Everything, hosts Laura Marsh and Alex Pareene talk with Alex Shephard, a staff writer at The New Republic and an inveterate Nobel watcher, about the enigmatic politics of the oldest and most distinguished literary prize in the world. Will the Nobel Committee salute freedom of speech by honoring Salman Rushdie, who was brutally attacked onstage in August? Will it recognize the French memoirist Annie Ernaux, who has written movingly about illegal abortion? How apparent have the Nobel's politics been over the years—and who definitely won't win? Learn more about your ad choices. Visit megaphone.fm/adchoices

My conversation with Elie Wiesel -- Holocaust survivor, author, and winner of the Nobel Peace Prize -- was recorded in 2013 for the 20th anniversary of the U.S. Holocaust Memorial and Museum. Our wide-ranging conversation includes memories of his childhood village in Hungary, his experience in the Nazi death camps, and his reflections on humor and friendship. The Nobel Committee, when awarding Wiesel the Peace Prize, stated: "Wiesel is a messenger to mankind: his message is one of peace, atonement and human dignity . . . ." The Committee cited Wiesel's "belief that the forces fighting evil in the world can be victorious . . . ." I like to think Wavemaker Conversations is where curiosity meets hope. And I believe that this conversation with Elie Wiesel takes us to that place.

In the 1970s a new method of helping the poorest people in the world emerged: microlending. The idea is to give the very poorest people, those who live on less than two dollars per day, very small loans they can use to start businesses and serve their community. Thanks to the power of success stories and anecdotes of those helped by microlending, the idea caught on with philanthropists and governments in the west. The concept enjoyed the full throated endorsement of the Clintons, The Nobel Committee, the United Nations, and experts working in global development. But a dark side of microlending quickly emerged. Some loans came with unreasonably high interest rates. Certain microlending institutions harassed and threatened those who couldn't pay. Some of those who received small loans found themselves trapped in a debt spiral. The indebted even committed suicide to escape the loan. While this was going on, some owners of microfinance ventures profited to the tune of millions of dollars. In the 2010s, multiple studies began to discover that the benefits of microlending as a poverty cure were vastly oversold. Microloans could in fact improve a community's economic base in certain situations. But they cannot and will not end poverty entirely, as its advocates claimed decades earlier. How did the most powerful, wealthy, and influential people in the world buy into the exaggerated promises of microlending? This is a 10-part series brought to you by the QAA podcast. To get access to all upcoming episodes of Trickle Down as well as a new premium QAA episode every week, go sign up for $5 a month at patreon.com/qanonanonymous Written by Travis View. Theme by Nick Sena (https://nicksenamusic.com). Additional music by Pontus Berghe & Nick Sena. Editing by Corey Klotz. REFERENCES Banerjee, Abhijit and Duflo, Esther (2011) Poor Economics: A Radical Rethinking of the Way to Fight Global Poverty Bateman, Milford (2010) Why Doesn't Microfinance Work: The Destructive Rise of Local Neoliberalism Edited by Bateman, Milford and Maclean, Kate (2017) Seduced and Betrayed: Exposing the Contemporary Microfinance Phenomenon Collina, Daryl et al (2009) Portfolios of the Poor: How The World's Poor Live on $2 a Day Meyerowitz, Joanne (2021) A War on Global Poverty: The Lost Promise of Redistribution and the Rise of Microcredit Rahman, Aminur (1999) Micro-credit Initiatives for Equitable and Sustainable Development: Who Pays? http://users.nber.org/~rdehejia/!@$devo/Lecture%2006%20Microcredit/extra/RAHMAN,%20A.%20Micro-credit%20initiatives%20for%20equitable%20and%20sustainable%20development%20who%20pays.pdf

This week the Nobel Committee awarded Maria Ressa and Dmitry Muratov the Nobel peace prize for their efforts to safeguard freedom of expression. Ressa and her attorney, international human rights lawyer Amal Clooney, join Fareed to discuss why fighting for a free press is essential in maintaining healthy functional democracies around the world. Then: on Wednesday, Taiwan's defense minister said that tensions with China are at their worst in 40 years, Fareed talks to former U.S. national security advisor Lt. General H.R. McMaster (Ret.) about the tense relationship between China and Taiwan and why the U.S. and its partners in the region need to aid Taiwan. As the northern hemisphere enters the winter months, the next energy crisis seems to be looming on the horizon. Tom Friedman, New York Times columnist, explains why there needs to be a global comprehensive energy plan that shifts to cleaner fuels. Plus, Fareed's book “10 Lessons for a Post-Pandemic World” comes out in paperback with a new afterword where he reflects on one more important lesson that he learned during the latter part of the pandemic: how individuals need to build inner resources of mind and spirit.   GUESTS: Maria Ressa, Amal Clooney, H.R. McMaster, Tom Friedman   To learn more about how CNN protects listener privacy, visit cnn.com/privacy