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What do Listerine strips, backyard barbecues, and cartoon characters have to do with kids meeting Jesus? More than you might think.In this lively and insightful episode of Candid Conversations, host Jonathan Youssef welcomes back Zack Carden—pastor, storyteller, and creator of Grey Bobby Ministries—to explore the incredible opportunity churches have with Vacation Bible School (VBS).Zack shares how his passion for the Gospel and kids collided unexpectedly, leading to years of creative VBS leadership that blends humor, theology, and deep discipleship. Together, they unpack why VBS still works, how it transforms both kids and teen volunteers, and what churches can do to make the most of this high-impact week.In this episode, you will learn:Why the 3–13 age window is spiritually criticalWhat unchurched families really think about sending kids to VBSHow to follow up meaningfully after the last water balloon popsThe simple tool Zack uses to draw kids (and their families) back to churchHow parents can disciple kids without feeling overwhelmedLearn how to use your church's VBS to reach your community and keep them coming back.Whether planning this year's VBS or wondering if it's still worth doing, this episode will reignite your vision for reaching the next generation with the Gospel.More from Zack Carden:Find Zack Carden's Biblical storytelling content for kids: Visit Greybobby MinistriesJonathan learns more about Greybobby from Zack: Listen hereRemember, it's not too late to register for VBS, invite a friend, or start planning for next year. Schedule it, defend it, and watch God move.
This podcast is brought to you by Outcomes Rocket, your exclusive healthcare marketing agency. Learn how to accelerate your growth by going to outcomesrocket.com AI and data are being used to transform consumer healthcare by personalizing experiences, reducing friction, supporting growth, and promoting sustainable innovation. In this episode of The Beat podcast, Bernardo Tavares, Chief Technology and Data Officer at Kenvue, discusses leveraging AI and data to transform consumer healthcare. He shares his journey from the tech industry to consumer goods and healthcare, emphasizing how technology can enhance the consumer experience. Kenvue, known for brands like Tylenol and Listerine, is the largest pure-play consumer health company and focuses on digital reinvention. Bernardo highlights how AI can personalize consumer interactions, reduce operational friction, and drive growth. He also discusses sustainability efforts, including a digital menopause platform aimed at breaking societal taboos. Tune in to discover how Kenvue is revolutionizing consumer healthcare with AI and data innovation Resources: Connect with and follow Bernardo Tavares on LinkedIn. Follow Kenvue on LinkedIn and Instagram and visit their website. Fast Track Your Business Growth: Outcomes Rocket is a full-service marketing agency focused on helping healthcare organizations like yours maximize your impact and accelerate growth. Learn more at outcomesrocket.com
Nossas amigas cientistas, Laura Marise e Ana Bonassa, do canal Nunca Vi 1 Cientista, se reúnem em mais um NerdCast para destruir alguns mitos da ciência e certos hábitos caseiros de que a Sra. Jovem Nerd tanto gostava — por que não? ESTÚDIO GGAC Desvenda os mistérios no livro-jogo Investigar: https://jovemnerd.page.link/Investigar_Livro_Jogo_NerdCast Conheça mais sobre o Estúdio GGAC: https://jovemnerd.page.link/Conheca_Estudio_GGAC XBOX Jogue agora South of Midnight no Game Pass: https://jovemnerd.page.link/South_Of_Midnight_NerdCast LISTERINE Aceite o desafio 21 dias LISTERINE® - Sua boca mais limpa ou seu dinheiro de volta: https://jovemnerd.page.link/Listerine_21_Dias_NerdCast_ *Comparado com apenas uso da escovação e fio dental. Ação válida de 17/02/2025 a 18/05/2025 ou até que se alcance o valor máximo em pedidos de reembolso previsto em regulamento, o que ocorrer primeiro. Para mais informações, consulte condições e regulamento completo em https://desafio21diaslisterine.com.br. O reembolso será correspondente ao valor de produtos comprados, sujeito ao limite de até R$60 (sessenta reais) por CPF, desde que atendido o regulamento. **Dados clínicos de redução de placa acima da linha da gengiva após profilaxia, uso complementar à escovação e fio dental. PEDIDOS DE DOAÇÃO Pedido de Doação de Sangue para Benedito Gomes da Silva que precisa de ao menos 20 doações. Local: Hemocentro HSP Unifesp - R. Dr. Diogo de Faria, 824 - Vila Clementino, São Paulo. Pedido de Doação de Sangue para Belmira Carmo de Albuquerque. Informar o nome da paciente. Local: ANEXO SANTA CASA DE CUIABÁ, R. Cel. Peixoto, 141 - Bandeirantes, Cuiabá - MT. Pedido de Doação de Sangue para Beatriz de Oliveira Souza. Local: Hemocentro HSP Unifesp - R. Dr. Diogo de Faria, 824 - Vila Clementino, São Paulo. Pedido de Doação de Medula Óssea urgente para o Carlos Eduardo Ferreira. Local: Qualquer estabelecimento do Hemominas mais próximo e doar em nome de Carlos Eduardo Morando Faria Ferreira. Um dos diversos endereços é: Posto Avançado de Coleta Externa (PACE) da Fundação Hemominas em Muriaé fica na Rua Dr. Ivan A. Porcaro, s/n, no Centro da cidade - Muriaé, MG. Pedido de Doação de Sangue para Vilson Bonfim dos Santos (Informar o nome do paciente). Local: Hospital Mário Covas - Rua Dr. Henrique Calderazzo, 321 - Paraíso-Santo André/SP Pedido de Doação de Sangue para Guillermina Rivero de Fernandez. Local: Av. Dr. Arnaldo, 251 - Cerqueira César, São Paulo - SP. * Acesse o site da Fundação Pró-Sangue. Faça o agendamento online e leve um documento de identidade original com foto recente. Todos os tipos sanguíneos, pois o banco de sangue está precisando muito. CONFIRA OS OUTROS CANAIS DO JOVEM NERD E-MAILS Mande suas críticas, elogios, sugestões e caneladas para nerdcast@jovemnerd.com.br APP JOVEM NERD: Google Play Store | Apple App Store ARTE DA VITRINE: Randall Random Baixe a versão Wallpaper da vitrine EDIÇÃO COMPLETA POR RADIOFOBIA PODCAST E MULTIMÍDIA
Vamos comentar sobre hábitos terríveis porém saudáveis, turismo pelo mundo (e pelo TikTok), fanfics e personagens de filmes que marcaram nossas vidas. Vem ouvir! MAGALU PAYDAY Aproveite as ofertas do Payday no Magalu: https://jovemnerd.page.link/Magalu_Payday_NerdCast LISTERINE Aceite o desafio 21 dias LISTERINE® : Sua boca mais limpa ou seu dinheiro de volta: https://jovemnerd.page.link/Listerine_21_Dias_Nerdcast *Comparado com apenas uso da escovação e fio dental. Ação válida de 17/02/2025 a 18/05/2025 ou até que se alcance o valor máximo em pedidos de reembolso previsto em regulamento, o que ocorrer primeiro. Para mais informações, consulte condições e regulamento completo em https://desafio21diaslisterine.com.br. O reembolso será correspondente ao valor de produtos comprados, sujeito ao limite de até R$60 (sessenta reais) por CPF, desde que atendido o regulamento. **Dados clínicos de redução de placa acima da linha da gengiva após profilaxia, uso complementar à escovação e fio dental. INTEL Ouça o NerdTech de hoje: https://jovemnerd.page.link/Intel_NerdTech_107_NerdCast PETROBRAS Conheça o projeto Lua da Petrobras: Lua é destaque na última edição da revista Communications of ACM: https://jovemnerd.page.link/Petrobras_Lua_CTC A Look at the Design of Lua: https://jovemnerd.page.link/Petrobras_Lua_Vimeo https://jovemnerd.page.link/Petrobras_Lua_ACM Linguagem LUA - Programação Criada por Brasileiros: https://jovemnerd.page.link/Petrobras_Linguagem_Lua_YT Petrobras e Roblox?: https://jovemnerd.page.link/Petrobras_Serie_Lua PEDIDOS DE DOAÇÃO Pedido de Doação de Doação de Granulócitos (similar a doação de plaquetas) e doação de sangue O+ e O- para Mariana Bianchi. Informar nome da paciente. Local: Banco de Sangue - Unidade Einstein Morumbi - Av. Albert Einstein, 627/701 - Morumbi, São Paulo - SP, 05652-900 Pedido de Doação de Sangue para Belmira Carmo de Albuquerque. Informar o nome da paciente. Local: ANEXO SANTA CASA DE CUIABÁ, R. Cel. Peixoto, S/N° - Bandeirantes, Cuiabá - MT, 78010-100. Pedido de Doação de Sangue para Benedito Gomes da Silva. Informar o nome da paciente. Local: Hemocentro Unifesp/HospitalSP - Hemocentro R. Dr.Diogo de Faria, 824, V. Clementino Pedido de Doação de Sangue para Pedro Henrique Silva Garcia. Informar data de nascimento: 11/12/2010 - Local: Rua Harry Dannemberg, 473 – Itaquera. São Paulo e principalmente a Zona Leste. Horário: Segunda a Sexta-feira, das 7h às 16h (limitado a 140 senhas/dia). Sábado das 7h às 12h (limitado a 120 senhas/dia) Pedido de Doação de Sangue tipo A+ e Plaquetas para João Pedro Voltolini Popelier. Local: Hospital Santa Casa de Misericórdia em Porto Alegre RS Internação: Hospital da Criança Santo Antônio. Pedido de Doação de Sangue para Caroline Pamela da Rocha. Local: PRÓ-SANGUE - Posto Clínicas. Av. Dr. Enéas Carvalho de Aguiar, 155 - 1° andar - Cerqueira César, São Paulo - SP. CONFIRA OS OUTROS CANAIS DO JOVEM NERD E-MAILS Mande suas críticas, elogios, sugestões e caneladas para nerdcast@jovemnerd.com.br APP JOVEM NERD: Google Play Store | Apple App Store ARTE DA VITRINE: Randall Random Baixe a versão Wallpaper da vitrine EDIÇÃO COMPLETA POR RADIOFOBIA PODCAST E MULTIMÍDIA
A segunda temporada de Ruptura chegou ao fim com uma produção de altíssimo nível, elenco afiado e uma trama que continua mexendo com a nossa cabeça! Vamos comentar tudo o que achamos dessa temporada impecável neste NerdCast. LISTERINE Aceite o desafio 21 dias LISTERINE® : Sua boca mais limpa ou seu dinheiro de volta: https://jovemnerd.page.link/Listerine_21_Dias_NC *Comparado com apenas uso da escovação e fio dental. Ação válida de 17/02/2025 a 18/05/2025 ou até que se alcance o valor máximo em pedidos de reembolso previsto em regulamento, o que ocorrer primeiro. Para mais informações, consulte condições e regulamento completo em https://desafio21diaslisterine.com.br. O reembolso será correspondente ao valor de produtos comprados, sujeito ao limite de até R$60 (sessenta reais) por CPF, desde que atendido o regulamento. **Dados clínicos de redução de placa acima da linha da gengiva após profilaxia, uso complementar à escovação e fio dental. MAGALU CLOUD Ouça o episódio de hoje: https://jovemnerd.page.link/Nerd_Na_Cloud_DeepSeek Conheça o Magalu Cloud: https://jovemnerd.page.link/Magalu_Cloud_NerdCast_1 LUIZA LABS Siga o Luiza Labs no Instagram: https://jovemnerd.page.link/Luiza_Labs_Instagram_1 Conheça o Blog do Luiza Labs: https://jovemnerd.page.link/Luiza_Labs_Blog_1 Acompanhe as vagas na Página de Carreiras: https://jovemnerd.page.link/Luiza_Labs_Pag_Carreiras_1 Confira as Vagas Quentes para o Luiza Labs: https://jovemnerd.page.link/Luiza_Labs_Vagas_Quentes OZOB: A CYBERPUNK BOARDGAME Faça parte do Financiamento Coletivo Internacional de OZOB: A Cyberpunk Boardgame: https://jovemnerd.page.link/Ozob_Gamefound_NerdCast PEDIDOS DE DOAÇÃO Pedido de Doação de Sangue para Pedro Henrique Silva Garcia. Informar data de nascimento: 11/12/2010 - Local: Rua Harry Dannemberg, 473 – Itaquera. São Paulo e principalmente a Zona Leste. Horário: Segunda a Sexta-feira, das 7h às 16h (limitado a 140 senhas/dia). Sábado das 7h às 12h (limitado a 120 senhas/dia) Pedido de Doação de Sangue tipo A+ e Plaquetas para João Pedro Voltolini Popelier. Local: Hospital Santa Casa de Misericórdia em Porto Alegre RS Internação: Hospital da Criança Santo Antônio. Pedido de Doação de Sangue para Caroline Pamela da Rocha. Local: PRÓ-SANGUE - Posto Clínicas. Av. Dr. Enéas Carvalho de Aguiar, 155 - 1° andar - Cerqueira César, São Paulo - SP. CONFIRA OS OUTROS CANAIS DO JOVEM NERD E-MAILS Mande suas críticas, elogios, sugestões e caneladas para nerdcast@jovemnerd.com.br APP JOVEM NERD: Google Play Store | Apple App Store ARTE DA VITRINE: Randall Random Baixe a versão Wallpaper da vitrine EDIÇÃO COMPLETA POR RADIOFOBIA PODCAST E MULTIMÍDIA
Qual é a pauta, nerds? Bichinhos de estimação fofinhos e bonitinhos, o passado de Pedro Duarte como encantador de pets, a nova cachorrinha do Sr.K e como vivem os ricos e seus mordomos. LISTERINE Aceite o desafio 21 dias LISTERINE® 5x : Sua boca mais limpa ou seu dinheiro de volta: https://jovemnerd.page.link/Listerine_21_dias_NerdCast *Comparado com apenas uso da escovação e fio dental. Ação válida de 17/02/2025 a 18/05/2025 ou até que se alcance o valor máximo em pedidos de reembolso previsto em regulamento, o que ocorrer primeiro. Para mais informações, consulte condições e regulamento completo em https://jovemnerd.page.link/Listerine_21_dias_NerdCast. O reembolso será correspondente ao valor de produtos comprados, sujeito ao limite de até R$60 (sessenta reais) por CPF, desde que atendido o regulamento. ** Dados clínicos de redução de placa acima da linha da gengiva após profilaxia, uso complementar à escovação e fio dental. NETSHOES Confira seu novo estilo no Aniversário Netshoes: https://jovemnerd.page.link/Netshoes_Aniversario_NerdCast NERDSTORE Confira o Mês do Consumidor na NerdStore: https://jovemnerd.page.link/NerdStore_Mes_Consumidor_NerdCast PEDIDOS DE DOAÇÃO Pedido de Doação URGENTE de Medula Óssea para Silvana Regina Juliani - Doações nas unidades: Irmandade da Santa Casa de Misericórdia de São Paulo: R. Dr. Cesário Mota Júnior, 112 - Vila Buarque, São Paulo | Hospital São Paulo - Hospital Universitário UNIFESP: Napoleão de Barros, 715 - Vila Clementino, São Paulo. A doação de medula é um processo simples mas muitas pessoas desconhecem. Qualquer pessoa saudável entre 18 e 35 anos pode doar. Pedido de Doação de Sangue URGENTE para Pedro Henrique Santos Rodrigues - Local: Hemonúcleo Costa Verde, R. Japoranga, 1700 - 2º andar - Japuíba, Angra dos Reis - RJ. Pedido de Doação de Sangue URGENTE para Antônia Alvina Celina da Silva internada na Santa Casa SP. Tipo sanguíneo -A e outros. Local: Rua Marquês de Itu, 579 - Vila Buarque, São Paulo. CONFIRA OS OUTROS CANAIS DO JOVEM NERD E-MAILS Mande suas críticas, elogios, sugestões e caneladas para nerdcast@jovemnerd.com.br APP JOVEM NERD: Google Play Store | Apple App Store ARTE DA VITRINE: Randall Random Baixe a versão Wallpaper da vitrine EDIÇÃO COMPLETA POR RADIOFOBIA PODCAST E MULTIMÍDIA
Vamos falar sobre o impacto da indicação e vitória do filme Ainda Estou Aqui na edição de 2025 do Oscar, além de comentar nossas impressões do filme e como sua mensagem pode impactar positivamente o público. DISNEY+ Assista a Demolidor: Renascido no Disney+ : https://jovemnerd.page.link/Demolidor_Renascido_NerdCast LISTERINE Promoção Desafio 21 dias LISTERINE® 5x mais poder de limpeza ou seu dinheiro de volta. Sua boca mais limpa ou seu dinheiro de volta.* Faça parte do Desafio 21 Dias com Listerine: https://jovemnerd.page.link/Listerine_21_Dias_NerdCast *Comparado com apenas uso da escovação e fio dental. Ação válida de 17/02/2025 a 18/05/2025 ou até que se alcance o valor máximo em pedidos de reembolso previsto em regulamento, o que ocorrer primeiro. Para mais informações, consulte condições e regulamento completo em https://desafio21diaslisterine.com.br. O reembolso será correspondente ao valor de produtos comprados, sujeito ao limite de até R$60 (sessenta reais) por CPF, desde que atendido o regulamento. NERDSTORE Confira a promoção Payday na NerdStore: https://jovemnerd.page.link/NerdStore_Payday_3_NC PEDIDOS DE DOAÇÃO Pedido de Doação URGENTE de Medula Óssea para Silvana Regina Juliani - Doações nas unidades: Irmandade da Santa Casa de Misericórdia de São Paulo: R. Dr. Cesário Mota Júnior, 112 - Vila Buarque, São Paulo | Hospital São Paulo - Hospital Universitário UNIFESP: Napoleão de Barros, 715 - Vila Clementino, São Paulo. A doação de medula é um processo simples mas muitas pessoas desconhecem. Qualquer pessoa saudável entre 18 e 35 anos pode doar. Pedido de Doação de Sangue URGENTE para Pedro Henrique Santos Rodrigues - Local: Hemonúcleo Costa Verde, R. Japoranga, 1700 - 2º andar - Japuíba, Angra dos Reis - RJ. Pedido de Doação de Sangue URGENTE para Antônia Alvina Celina da Silva internada na Santa Casa SP. Tipo sanguíneo -A e outros. Local: Rua Marquês de Itu, 579 - Vila Buarque, São Paulo. CONFIRA OS OUTROS CANAIS DO JOVEM NERD E-MAILS Mande suas críticas, elogios, sugestões e caneladas para nerdcast@jovemnerd.com.br APP JOVEM NERD: Google Play Store | Apple App Store ARTE DA VITRINE: Randall Random Baixe a versão Wallpaper da vitrine EDIÇÃO COMPLETA POR RADIOFOBIA PODCAST E MULTIMÍDIA
Mikey Kampmann from 2 Wet Crew joins Brendon in the studio to meet Stephán in person! We make some calls, drink Listerine, and have some fun! Keeping the vibes POSITIVE and CHILL. Here's Mikey's Instagram: https://www.instagram.com/babyfacedjunkie/?hl=en Check out Stephán here: https://open.spotify.com/artist/75HRlkFN40zeHpcoeIjwXo?si=eSAl2B1zQIyP36Y0EswXuA&nd=1&dlsi=6c21393dbcf14399 https://www.instagram.com/_gold.lotus_?utm_source=qr Join the Patreon! https://www.patreon.com/worldrecordpodcast Watch videos, buy merch https://worldrecordpodcast.com/
Tim Otis is an actor who has appeared in countless film and TV projects and has done, in his career, easily over, get this - a staggering 100 commercials. When both your father and your step-father were working actors - from the old Hollywood guard of the 50's through to the noughties chances are you'll land somewhere in the entertainment industry. Tim is also primarily a DJ, a radio presenter, and an audiophile. He's also a dad, a husband, a brother to fellow actor Ted Otis Jr. and son of an heiress to the Listerine fortune. He also works tirelessly and passionately with individuals seeking recovery from addiction.
In this series, Jeff & Andy dive into a mix of useless facts, myths, forgotten stories, and strange truths. In this episode, Jeff gives the top selling menu items at McDonald's and Andy shares the story of how bad breath become taboo. This series is presented to you by the great folks over at Mallard Bay. Whenever you are looking to book your next outdoor adventure, head over to Mallard Bay and search through their verified outfitters to remove the guess work when booking.
Piezo touch and pressure-sensing ion channels are showing up everywhere as the explanation for physiologic phenomena, both at the macro and micro levels. Ardem Patapoutian, my friend and colleague at Scripps Research, discovered these receptors back in 2010 and was awarded the Nobel Prize in 2021 for his work. As you'll see/hear from our conversation, the field has exploded. And you'll get to know Ardem, who is such a fun, charismatic, and down-to-earth person. He also recently got a unique tattoo (videos below) and I wonder (unlikely) if any other Nobel laureates have one related to their discovery?!Below is a video clip from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The current one is here. If you like the YouTube format, please subscribe! The audios are also available on Apple and Spotify.Transcript with links to audioEric Topol (00:07):Well, hello. It's Eric Topol with Ground Truths, and I've really got a special guest today. The first time for the podcast, I've been able to interview a colleague and faculty at Scripps Research, Ardem Patapoutian, who just by the way happens to be the 2021 Nobel Laureate in Physiology or Medicine. So welcome, Ardem. It's so wonderful to have you.Ardem Patapoutian (00:30):Thanks so much, Eric. Looking forward to chatting with you.Eric Topol (00:34):Well, this has been interesting because although I've known you for several years, I didn't research you. I mean, I had to learn about more than I even do. And of course, one of the great sources of that is on the Nobel Prize website where you tell your whole story. It is quite a story and not to review all of it, but I wanted to go back just before you made the call to move to Los Angeles from Beirut, Lebanon and with the scare that you went through at that time, it seemed like that was just extraordinary that you had to live through that.Ardem Patapoutian (01:11):Yeah, so I am of Armenian origin, but I was born in Lebanon and born in 1967, so I was eight years old when the civil war started. So it's a kind of bizarre childhood in the sense that with all the bombs and fighting in Lebanon. So it was tough childhood to have, but it was never personal. It was bombs and such. And so, the event you're talking about is, I happened to be kidnapped while crossing East to West Beirut. They only held me for four or five hours at first asking me questions to see who I am, but I think they pretty soon figured out that I was not a dangerous guy and they ended up letting me go. But before that, that incident really had a huge impact on me so that by the time I got home, I literally said, I'm out of here. I'm going to find a way to leave the country. And so, that's what, very quickly within a few months I packed and came to United States.Eric Topol (02:19):And how did you pick LA to be your destination?Ardem Patapoutian (02:22):Being from the Armenian community, there's a lot of Armenians in Los Angeles. My cousins already had moved there. They also grew up in Lebanon. And my brother, who's a few years older than me, got admitted to USC graduate school in engineering. So he was going to be there. So it made a lot of sense.Eric Topol (02:44):Oh yeah.Ardem Patapoutian (02:45):Unlike him, I came with no school or job prospects because it happened so fast that I kind of just left. One year I was at American University of Beirut for one year, but then just left and came here. So worked for a year in various jobs and then started going back to school to UCLA.Eric Topol (03:07):Yeah, I saw how there was about a year where you were delivering pizzas and before you got into UCLA, and that must have been an interesting off year, if you will. Well, the story of course, just to fast forward, you did your baccalaureate at UCLA, your PhD at Caltech, postdoc at UCSF, and then you came to Scripps Research 24 years ago along with Pete Schultz, and it's been quite an amazing run that you've had. Now, before we get into PIEZO receptors, the background, maybe you could help me understand, the precursor work seems to be all related to the transient receptor potential (TRP) series, also ion channels. They were of course related to whether it was heat and temperature or somatosensory. How do these channels compare to the ones that you discovered years later?Background on these Ion ChannelsArdem Patapoutian (04:09):Yeah, so the somatosensory neurons that innervate your fingertips and everywhere else in your body, their main job is to sense temperature and pressure. And this is very different than any other neuron or any other cell. So when you touch a hot stove that's burning hot, you need to know about that immediately within milliseconds or something cold. So the opposite side of it is pressure sensing, and it also comes in light touch, which is pleasant or a hammer hitting your finger, which is unpleasant. But all of these have the same characteristic anyway, that is your body has learned at the molecular level to translate a physical stimulus such as temperature and pressure into an electrical signal that neurons use to communicate with each other. But this idea of how you translate physical stimuli into chemical or electrical signal has been a long open question because as you know, most of our cells communicate by chemicals, whether that's hormones or small molecules, we know how that works, receptor bind to ligand, confirmational change and you get a kinase activation and that's enough. But here, how do you sense pressure? How do you sense temperature? It was just, there wasn't much known about that. And that's why our earlier work on TRP channels, which were temperature sensors came before the pressure. And so, they're very related in that sense.Eric Topol (05:52):The structure of these, if you were to look at them, do they look pretty similar? What the TRP as you say, and what you did back in the 2010 Science paper, which we'll link to, of course the classic paper where you describe PIEZO1 and PIEZO2, but if you were to look at this structures, would they look pretty similar?Ardem Patapoutian (06:14):No, that's a good question. And they absolutely don't. That's why finding these receptors were so hard. So if you go back to other sensory receptors, vision rhodopsin G-protein coupled receptor (GPCRs), larger G-protein coupled receptor look the same. So for example, when it was identified by chemically, that smell also works through G-protein coupled receptor. Richard Axel and Linda Buck, who also won the Nobel Prize, found those receptors by homology to visual GPCRs. The ion channels other than the fact that they crossed the membrane a few times or more, they have nothing else in common. If you looked at their structure, you can't even immediately tell they're ion channels. So you couldn't find these by structural homology or sequence homology. So you had to do something else. And usually that means functional screens and et cetera.Eric Topol (07:09):Well, yeah, and I'm in touch with the screening. We'll get to that and how you dig these up and find them. But the somatosensory ones are really interesting because I don't think a lot of people realize that when you have wasabi or you have Listerine mouthwash and feel the burn and that these are all mediated through these channels, right?Ardem Patapoutian (07:35):Yeah. So there's this whole field of chemesthesis, which means senses in your mouth, for example, that are not explained by taste transduction and olfactory. And these are actually by the same somatosensory neurons that help you sense temperature and pressure. And some of these receptors are the same. Their evolution has taken over and used them for many different things. The prime example of this is the capsaicin receptor that David Julius my co-laureate identified, which is also heat receptors. So all languages describe chili peppers as hot, and that's not a coincidence. It actually activates heat activated channel, and that's why we think of it as hot. And so, the same goes to another one of these TRP channels that you mentioned, which is TRPA1, and this one is also activated, but a lot of spicy foods other than the chili pepper active ingredient includes what's in garlic and onions and everything that has this burning sensation and chemicals of this and wasabi and chemicals of this are used in over the counter products like Listerine that cause that burning sensation.Eric Topol (08:54):So when you're chopping onions and it makes you cry, is that all part of it as well?Ardem Patapoutian (08:59):That's all TRPA1, yeah.The Discovery, A Test of PerseveranceEric Topol (09:01):It's wild. Now, this was the groundwork. There were these heat temperature and somatic sensory, and then you were starting to wonder what about touch, what about out pressure and proprioception. And so, you went on a hunt, and it's actually kind of an incredible story about how you were able to find out of these cells that you had, screening hundreds or I guess you got to 72 different small interfering RNA blocking that you finally found the one. Is that right?Ardem Patapoutian (09:37):That's right. So in retrospect, looking back at it, I think there's such an interesting scientific message there. And so, many of us were looking for this touch pressure sensors and we were all looking in the DRG sensory neurons that are complicated heterogeneous, they don't divide. It's not easy to do a screen on them. And ultimately after a lot of failures, what worked for us is to take a step back and ask a much more simpler question. And that was, can we find one of these cell lines that you could easily homogeneously grow in a culture dish, if they respond to mechanical force, can we find our channel there? And then go back and look if it's relevant in vivo for what process. So I think the message is ask the simplest question to answer the question you're after. And finding what that is, is actually the challenge lots of times.Ardem Patapoutian (10:36):But yeah, that's what Bertrand Coste in my lab did is found a simple cell line that neuroscientists had been using for a hundred years and somehow found that they over overexpressed this channel because you can record from them, you can push them and record the currents from them. And then it became a simpler question of finding it. It still took a whole year. He made a list and one by one knocking them out and looking at it. And finally, as you say, number 72 was the hit. When he knocked that out, the current was gone. And that's where we started believing that we have what we were looking for.Eric Topol (11:12):Were you all ever about ready to give up at that point?Ardem Patapoutian (11:16):Oh yeah. I mean that's another lesson. These are postdocs doing the work, right? And they're here three, four years and this was coming close to end of two years, and he didn't have anything yet. So we started talking about having a backup project and he started that and we said, okay, we were ordering this oligos 30 at a time because they're expensive. And so, the first 30 nothing, the second 30 nothing. And how many more are we going to do before we potentially give up? And we said, well, let's do at least a third and then decide, thank goodness it was in that last set.Eric Topol (11:54):Wow, that is so wild. Now what's happened since this discovery, which I guess when you published it in 2010, so it means 14 years ago, but we're on this exponential growth of learning that these piezo receptors are everywhere. They're doing everything. In fact, I recently put on Bluesky, PIEZO ion channels are to human physiology as GLP-1 drugs are to treating many diseases because it's just blowing up. And you've published on some of these of course, on itch and bladder function and vascular function. We'll get to maybe malaria, I mean, but even the cover of Science recently was about wet dog shakes and how animals shake because of water. These receptors are so fundamental to our function. So maybe you could comment, 15 years ago when you were doing the work and you're making this discovery, did you ever envision it was going to blow up like this?Ardem Patapoutian (12:57):Not to this level, but I should have. I think that this idea, again, that most of cell communication is through chemicals is of course a lot of it is true.Ardem Patapoutian (13:12):But it would be ridiculous for evolution to ignore all the physical forces, the pressures that cells experience. And once they do, you would think you would put an instructive way of sensing this pressure signal and using it beneficially to the system or the cell. And so, when we used to talk about pressure sensing at the beginning, there were a couple of touch, pain, maybe proprioception, hearing are like the poster children of pressure sensing. But I think what these molecules, as you say is enabling us is finding out the much more wider role that pressure sensing is playing in physiology and in disease that no one had thought seriously about. And this is, I compare sometimes the finding the PIEZO molecules. You're going in a dark room, and you need to find a door to get into there. And PIEZO is kind of that finding the door once you get in, now you use that molecule now to find physiology instead of the opposite way around. So by pursuing PIEZO expression and function, we're finding all these new roles that they play in physiology and in disease that we didn't think about. And because they're so specialized to sense tension, membrane tension, they don't do anything else. So if you see them expressed somewhere or if you see a function for them, you can bet that they are playing a role in sensing pressure. A lot of biology has kind of come from this hypothesis.Eric Topol (15:00):Well, I mean it is so striking to see the pervasiveness, and I do want to go back just for a second because when you name them PIEZO, you named it after the Greek word. How did you come to that name?Ardem Patapoutian (15:13):So Bertrand and I were actually sitting on Google Translate and we were typing pressure and trying to see what it's like in Greek or in Latin or different languages. His native French and my Armenian and píesi in Greek is pressure. And of course, what's really cool is that the word that more people know about this is piezoelectric device.Eric Topol (15:41):Oh, right.Ardem Patapoutian (15:41):Actually, translates physical force into electricity and vice versa. And in a way, this is a little molecular machine that does the same thing, and he uses this piezoelectric device to actually push on the cell. That's his assay. So it all came together as a very appropriate name for this gene and protein.Call from the Nobel CommitteeEric Topol (16:04):Oh really, it's perfect. And you get to name it, even that's fun too, right? Now we're going to go to getting the call at 2:00 AM, but it didn't come to you because your phone from the Nobel Committee was on ‘do not disturb' and your 94-year-old father, Sarkis. How did the Nobel Committee know to get ahold of him? How did they reach him in the middle of the night?Ardem Patapoutian (16:37):Yeah, so I mean, since receiving it, I've had conversations with various committee members, and they are very resourceful folks, and they have assistants who throughout the year collect information on all potential people who might win. They're also doing last minute searches. So they looked for other Patapoutian's in California. So they just called my dad who initially yelled at them for disturbing him at 2:00 AM.Eric Topol (17:17):And he could get through to you because he was not on your list of ‘do not disturb' or something like that.Ardem Patapoutian (17:22):I didn't even know this. And I don't know if the policy has changed, but in some phones the ‘do not disturb' if it's called by someone who's in your contacts or favorites.Ardem Patapoutian (17:34):After I think they called twice and they get through, and that's how.Getting a Tattoo!Eric Topol (17:39):That's amazing. Wow. Well, that's quite a way to find out that you're getting recognized like this. Now recently you got a tattoo, which I thought was really remarkable, but we're going to put that of course in the post. Tell us about your decision to get the PIEZO channel on your arm.Ardem Patapoutian (18:02):So as you can tell, I'm obsessed about PIEZO and it's been good to me. And I had the idea a while ago, and my very wise wife, Nancy Hong, said that you might be going through midlife crisis. Why don't you wait a year? If you still believe in it, you should do it. And that's what I did. I waited a year, and I was like, I still want to do it. And I guess I could show it. Here it is.Eric Topol (18:32):Oh yeah, there it is. Oh wow.Ardem Patapoutian (18:33):What's cool is that I can pretty much flex to show the activation mechanism because the channel is like bent like this in the plasma membrane. When it's stretched, it opens and it actually flattens like this. So I feel like other than being a tattoo, this is both performance art and instructional device. When I'm giving talks without PowerPoint slides, I could give a demonstration how this ion channel works.[Below is from a presentation that Ardem recently gave, the Harvey Lecture, at Rockefeller University.]Eric Topol (19:04):It's wild. Now how did you find a tattoo artist that could, I mean, it's pretty intricate. I mean, that's not your typical tattoo.Ardem Patapoutian (19:14):Yeah, I put it up on social media that I was thinking of doing this, and many scientists are into tattoos, so I actually got so many recommendations. And one of them was a local here in San Diego, and she is very popular. I waited six months to get this, I was on a waiting list. The appointment was six months off when we made it. So she's very popular and she's very good.Eric Topol (19:45):Was it painful to get that done?Ardem Patapoutian (19:47):Well, that's actually really cool, right? Because PIEZO2 is involved in pain sensation, and I felt it while it was being tattooed on my arm. The whole day, I was there like six and a half hours.New Prospect for Pain MedicationEric Topol (20:00):Oh my gosh. Wow. Now that gets me to pain because, I'd like you to talk a bit about the people that don't have mutations or loss of function PIEZO receptors and also what your thoughts are in the future as to maybe we could develop a lot better pain medications.Ardem Patapoutian (20:22):Yeah, we're working on it. So you're right. One of the great parts of the science story, and this is mainly the work of Alex Chesler and Carsten Bönnemann at the NIH, where they identified people who came to the clinic for undiagnosed conditions, and they were uncoordinated and had difficulty walking. And when they did whole-exome sequencing, they found that they had mutations in PIEZO2, there were loss of function, as you say. So complete loss on both chromosomes. And when they started testing them, they realized that just like we had described them in animal models, humans without PIEZO2 as well, didn't sense touch, don't have proprioception. This sense of where your limbs are, that's so important for balance and most other daily functions that we take it for granted. So they were completely lacking all of those sensations. They also do not feel their bladder filling.Ardem Patapoutian (21:26):And so, they have learned to go on a schedule to make sure they don't have accidents. And many of these projects that we've done in the lab collaboration with Alex Chesler, et cetera, have come from the observations of what else these individuals experience. And so, it's been a great kind of collaboration communication between mechanistic animal model studies and the clinic. And so, one of the things that these individuals don't sense in addition to touch, is something called tactile allodynia, which is simply when touch becomes painful. You and I experienced this after small injury or sunburn where just touching your shoulder becomes painful, but for peripheral neuropathy and other neuropathic pain conditions, this is one of the major complaints that individuals have. And we know from the NIH studies that these individuals don't have this tactile allodynia. So touch becomes painful and doesn't apply to them, which tells us that if we block PIEZO2, we can actually get interesting relief from various aspects relative to neuropathic pain on other pain related neuropathies. But given everything we talked about, Eric, about how this is important for touch and proprioception, you don't want to make a pill that blocks PIEZO2 and you take it because this will have some serious on target side effects. But we are developing new compounds that block PIEZO2 and hope that it might be useful, at least as a topical medication pain and other indications. And we're actively working on this, as I said.Eric Topol (23:15):Yeah, I mean the topical one sounds like a winner because of peripheral neuropathy, but also I wonder if you could somehow target it to sick cells rather than if giving it in a systemic targeted way. I mean it has tremendous potential because we are on a serious hunt for much better relief of pain than exists today.Ardem Patapoutian (23:41):Absolutely.Eric Topol (23:42):Yeah. So that's exciting. I mean, that's another potential outgrowth of all this. Just going back, I mean the one that prompted me in November to write that about the human physiology in PIEZO, it was about intestinal stem cell fate decision and maintenance. I mean, it's just everywhere. But the work you've done certainly now has spurred on so many other groups to go after these different and many unanticipated functions. Were there any ones, of course, you've been pretty systematically addressing these that actually surprised you? You said, oh, are you kidding me when you read this? I never would've guessed this, or pretty much they followed suit as things were moving along.Ardem Patapoutian (24:33):So one of them is this role in macrophages that I found fascinating that we found a few years ago. So again, this came from human studies where PIEZO1 gain-of-function mutations. So in relation to loss of function, their gain-of-function where there's more activity given a certain amount of pressure. They have dehydrated red blood cells, which I'm not going to talk about right now. But they also have shown that in these patients, individuals, it's not really that pathological. They also have age-onset iron overload. What does that have to do with pressure sensing? And we brought that information into animal models, and we found that macrophages, their rate of phagocytosis depends on PIEZO, so that if you have too little PIEZO, they don't phagocytosis as much. If you have too much PIEZO, the phagocytosis too much. And this increased rate of phagocytosis in the long term because it's constantly eating red blood cells and the iron is circulating more causes long-term effects in iron overload. And again, as you kind of set that up, who would've thought that mechanical sensation is important for this basic hematology type?Eric Topol (25:52):Yeah, I mean, because we've been talking about the macro things, and here it is at the cellular level. I mean, it's just wild.Ardem Patapoutian (25:59):If you go back and look at a video of a macrophage eating up red blood cells, then you go, oh, I see how this has to do with pressure sensing because it is like extending little arms, feeling things letting go, going somewhere else. So again, I want to bring it back by this simple cell biological function of a cell type, like macrophage, exploring its environment is not just chemical, but very mechanical as well. And so, in retrospect, it is maybe not that surprising, that pressure sensing is important for its physiology.Career Changing?Eric Topol (26:33):Yeah, that's extraordinary. Well, that gets me to how your life has changed since 2021, because obviously this a big effect, big impact sort of thing. And I know that you're the first Armenian, first person from Lebanon to get this recognition. You recognized by the Lebanese Order of Merit. There's even a stamp of you, your picture characterized in 2022.Eric Topol (27:04):So if you were to sum up how it's changed because I see no change in you. You're the same person that has a great sense of humor. Often the tries to humor relaxed, calming. You haven't changed any to me, but how has it affected you?Ardem Patapoutian (27:26):Thank you, Eric. That's very kind of you. I try very hard for it not to change me. I do get a little bit more attention, a ton more invites, which unfortunately I have to say no to a lot of them because, and I'm sure you're very familiar with that concept and a lot of things are offered to you that I feel like it's so tempting to say yes because they're wonderful opportunities and an honor to be asked. But the end of the day, I'm trying to be very disciplined and not taking things on that I can do as an opportunity. But things that I really want to do. I think that's so hard to do sometimes is to separate those two. Why am I doing this? Is this really important for the goals that I have? So in one way, the answer for that is that I just want to stay in the lab and do my research with my students and postdoc, which is what I enjoy the most. But on the other hand, as you said, being the first Armenian who's received this, literally after the Nobel, I got this whole elementary school, all Armenian kids write to me multiple letters.Ardem Patapoutian (28:39):And they said, you look like me. I didn't think I could do this, but maybe I can. So in a sense, to ignore that and say, no, I just want to do my science, I don't want to be involved in any of that is also wrong. So I'm trying to balance being engaged in science outreach and helping to make science understood by the general public, realize that we're just regular people and at the same time how awesome science is. I love science and I like to project that, but leave plenty of time for me to just be a scientist and be in my lab and interact with my colleagues at Scripps, including you.Immigrant ScientistsEric Topol (29:21):Well, we're so lucky to have that chance. And I do want to mention, because you're prototyping in this regard about great immigrant scientists and other domains of course, but every year the Carnegie Foundation names these great immigrants and one year you were of course recognized. And in recent years, there have been more difficulties in people wanting to come to the US to get into science, and they wind up going to other places. It seems like that's a big loss for us. I mean, what if we weren't able to have had you come and so many hundreds, thousands of others that have contributed to this life science community? Maybe you could comment about that.Ardem Patapoutian (30:10):Yeah, I think it is tragic, as you say. I think in some circles, immigrants have this negative image or idea of what they bring, but at every level, immigrants have contributed so much to this country. It's a country of immigrants, of course, to start with. And I think it is important to put up a positive image of immigration and science is the ultimate example of that, right? I mean, I think when you go into any laboratory, you probably find if there's a lab of 16 people, you probably find people from 10 different countries. And we all work together. And the idea of also immigrant and especially about science is that I'm a big believer of changing field, changing things because just like that, immigrants have changed their whole life. So they come to a new culture, they bring with them their own way of thinking and their way of seeing things. And then you come into a new environment, and you see it a little bit differently. So that kind of change, whether it's because of physical immigration or immigrating from one field to another in science is really beneficial for science and society. And I think positive examples of this are an important part of highlighting this.Eric Topol (31:40):I couldn't agree with you more really.Bluesky vs Twitter/XEric Topol (31:41):Now, speaking of migration, there's been recently a big migration out of X, formerly Twitter to Bluesky, which I like the metaphor you liken to the Serengeti. Can you tell us about, now I know you're posting on Bluesky and of course so many others that you and I are mutual contacts, and our different networks are. What do you think about this migration outside of what was the platform where a lot of this, we shared things on X or before Musk took over known as Twitter? Thoughts about Bluesky?Ardem Patapoutian (32:27):Yeah, I think I use social media for a few reasons. The number one reason should be is to see new science by colleagues. My main point is that, but also, again, having fun in science is a big part of my draw to this. And as you can see from my posts, it's a bit lighthearted, and that's really me.Eric Topol (32:52):Right. Yeah.Ardem Patapoutian (32:52):I think on Twitter, things start getting a little bit dark and too many negative comments, and it was just not productive. And I just felt like after the elections, I felt like it was time to migrate. And I find Bluesky a great scientific community, and it's remarkable how quickly people have migrated from Twitter to Bluesky. But the counter argument for this is that you should stay in a place where majority of people are, because being in a bubble surrounding yourself by people like you doesn't help society. And so, I get that perspective as well. It just depends on what you're using the platform for and it's a difficult issue. But yeah, I've taken a break probably long-term break from Twitter. I'm on Bluesky now.Eric Topol (33:48):Yeah, no, the point you're bringing up about the echo chamber and is there going to be one for people that are leaning one way and they're thinking, and another with a whole different, often politically charged and even extreme views? It's really unfortunate if it does wind up that way. But right now, it seems like that migration is ongoing and it's substantial. And I guess we'll see how it settles out. I share your concern, and so far, I've been trying to keep a foot in both areas because I think if we all were to leave, then we're just kind of caving into a, it's tricky though. It really is because the noxious toxic type of comments, even when you try to avoid comments, you say, only followers can make a comment, they'll of course, quote your thing and then try to ding you and whatever. It's just crazy stuff, really.Ardem Patapoutian (34:53):I mean, what I think is that, that's why I said depends on why. I mean, your presence on social media is such an important part of science education. And I could almost say you can't afford to do what I do, which is I'm just putting my goofy posts and having fun. So we have different purposes in a way, and yeah, that affects what you use and how you use it.Eric Topol (35:17):Yeah, no, it's tricky it really is. We covered a lot of ground. Is there anything I missed that you want to get out there? Any part of this, your story and the PIEZO story, science and everything else that I didn't bring up?The Essentiality of Basic ScienceArdem Patapoutian (35:42):I just think that the basic science community is really suffering from decreasing amounts of funding and appreciation of doing basic science. And one of my goals, in addition to this immigrant scientist thing, is to remind people that all medicines start with basic science work. And funding this has mainly been through NIH and it's getting harder and harder for basic scientists to secure funding and I'm really worried about this. And we need to find ways to be okay for people to do basic science. And I'll give you one example. Whenever we make a publication and there's a journalist talking to us or some kind of press coverage, they ask, how is this directly affecting patients? And my work actually is very much related to patients, and I answer that question, but I also say, but it's also important to do science for the science sake because you don't know where the applications are going to come from. And we need to, as a society, encourage and fund and support basic science as the seeds of all these translational work. And I think doing that just kind of highlights that this is important too. We should support it, not just things that right now seem very related to translational that directly helps patients.Eric Topol (37:16):Well, I'm so glad you emphasized that because I mean, the PIEZO story is the exemplar. Look what's come of it, what might still come of it. In many respects here you are maybe 15 years into the story and there's still many parts of this that are untold, but if it wasn't for the basic science, we wouldn't have these remarkable and diverse insights. And recently you cited, and I think so many people read about the ‘crown jewel' NIH, front page New York Times, and how it's under threat because the new NIH director doesn't have a regard for basic science. He's actually, he's confirmed, which is likely, he's an economist, physician economist, never practiced medicine, but he doesn't really have a lot of regard for basic science. But as you point out, almost every drug that we have today came out of NIH basic work. And I mean, not just that, but all the disease insights and treatments and so much.Eric Topol (38:25):So this is really unfortunate if we have not just an NIH and other supporting foundations that don't see the priority, the fundamental aspect of basic science to then lead to, as we call translational, and then ultimately the way to promote human health, which is I think what we're all very much focused on ultimately. But you can't do it without getting to first base, and that's what you have done. You served it up and it's a great example. Well, Ardem, it's always a pleasure. This is a first time talking through a podcast. I hope we'll have many, many visits informally that will complement the ones we've already had, and we will follow the PIEZO work. Obviously, you have had just an exceptional impact, but you're still young and who knows what's next, right? I mean, look what happened to Barry Sharpless. He won here. He won two Nobel prizes, so you never know where things are headed.Ardem Patapoutian (39:36):Thank you, Eric, and I really appreciate what you do for the biomedical community. I think it's wonderful through your social media and this podcast, we all appreciate it.***********************************************************************************Please take a moment to complete the poll above.Thank you for reading, listening and subscribing to Ground Truths.If you found this informative please share it!All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and of course appreciated. All proceeds from them go to support Scripps Research. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. I welcome all comments from paid subscribers and will do my best to respond to each of them and any questions.Thanks to my producer Jessica Nguyen and to Sinjun Balabanoff for audio and video support at Scripps Research.And Happy New Year! Get full access to Ground Truths at erictopol.substack.com/subscribe
“I was the highest paid actor in Hollywood -- if you were counting by the word.” - actor Eric Brown THE CONVERSATIONTAKING THE PIPPIN BUS: Nine-year-old Eric played the lead in the original touring company of Bob Fosse's Pippin! “It was 1974. I was the only child in a cast of adults. One-and-two-night stands. In a bus. Thirty states. Six months.”PRIVATE LESSONS: The lead got fired -- so Eric was promoted to star!15 GOING ON 30: In Private Lessons, Fifteen year-old Eric Brown, played a fifteen-year-old -- being seduced by a thirty-year-old woman! “My wife is still mad at my mother for letting me play that role!”KICKED OUT OF SCHOOL: Eric was kicked out of St. Francis Prep School for being in Private Lessons: “They said, “We think you'd do better at another school considering your career goals.” It was a very Franciscan way of saying, “Get out”.”MAMA'S FAMILY: “You know the rumors that Betty White had a dirty streak? All true.”On working with Carol Burnett, Vicki Lawrence, Dorothy Lyman, Betty White, Rue McClanahan and Harvey Korman: “Everyone was so funny -- you were always laughing. They were constantly futzing, because they knew what was funny -- and if it wasn't, they would fix it."DIRECTOR SPLIT: Mama's Family had TWO directors: Harvey Korman worked with the actors, while someone else blocked out the camera moves (Roger Beatty).THE METAVERSE OF MAMA'S FAMILY: Vicki Lawrence started playing the at least 63-year-old “Mama” when she was in her late 20's!THE EPISODE THAT NEVER WAS: Eric pitched an episode where he and Ken Barry -- both tap dancers -- could dance together in a talent show. But it never happened.TAKE THE TOUPEE: Carol Burnett would do anything for a laugh -- including pulling the hairpiece off a certain co-star during taping -- when no one was expecting it!BAD NEWS, GOOD NEWS, WORSE NEWS -- Mama's Family gets cancelled. Then it comes back! But not with Eric.LOVING LAURA HOLT: After Private Lessons, Eric did a replay on Remington Steele -- playing a kid with a crush on an “older woman”: “I was head over heels in love with Stephanie Zimbalist. In real life!”BE KIND, REWIND: After jobs dried up in Hollywood, Eric moved to Monterey and got a job in a video store: “I was renting movies to people that I WAS IN.”FIRST RULE OF COMMUNICATION: For the MacArthur Foundation or a lost chicken in Queens: Know your goal.WHAT CAN ONE PERSON DO TO HELP THE WORLD? Find what you love and offer that.So, join Susan and Sharon -- and Eric -- as they talk Listerine commercials, the Clinton campaign, Jon de Bont, Sarah Jessica Parker, Howard Hessman, Barry Williams, On Golden Pond, Ian Ziering, curfew “double standards”, working with women directors, Jerry Reed, Emmanuelle, Fred Willard -- and evil twins! AUDIO-OGRAPHYWatch Mama's Family for free on Pluto TV.Listen to Eric Brown's podcast about philanthropy, Let's Hear it. Or on Apple. Check out what Eric Brown is doing now at Brownbridgestrategies.com.Enjoy Eric's blog about traveling the world with his wife at Eat, Bicker, Love.PLUS -- AN “80's TV LADIES” HOLIDAY SALE!Get 15% off on all merch at 80s TV Ladies Shop on Fourthwall.Make sure to use promo code “Festive80s”! CONNECTVisit 80sTVLadies.com for transcripts.Sign up for the 80s TV Ladies mailing list.Support us and get ad-free episodes on PATREON.This year is the 45th anniversary of President Carter's Crisis of Confidence speech. Get Susan's new play about it: Confidence (and the Speech) at Broadway Licensing.
A gente recebe hoje ela que é considerada uma grande líder: por sua experiência, força, garra e resiliência, mas acima de tudo, pelo forte senso de inspirar e ajudar as gerações de atletas do seu esporte. Como a maioria, começou cedo, participou de várias competições internacionais e, nesse ano, 2024, junto com sua equipe, conquistou sua primeira medalha olímpica
Barking Blondes Anna Webb and Jo Good are perhaps the two funniest ladies you've ever heard. They have an affinity for our "fur-kids" - and they'll tell you how two bitches taught two bitches to survive without men. Listen Now Flea Fodder Once again, we are having a record year for fleas. And this has, quite by accident, become the thrust of today's show. Dr. Cristiano Von Simpson and "Dogfather" Joey Villani offer up great advice for ridding your pet of fleas once and for all. Can you use Listerine or Vinegar as effective protection? Dr. Debbie busts the myths. Listen Now Rent-The-Chicken.com Phil Thompkins and his wife Jenn are quite the entrepreneurs. They've successfully launched a chicken rental business just in time for a renewed interest in the feathered fowl. "Chickens are the new dogs," and many simply like having the egg supply. Listen Now Zero-Tolerance For People Wearing Animal Prints A wildlife park in the U.K. has started banning animal print clothing after zookeepers noticed the fashion choice was confusing the animals. The Chessington World of Adventures has even brought in "Animal Print Bouncers" to make sure visitors don't get in wearing anything patterned after zebras, giraffes, leopards, tigers, or other wild animals. Listen Now What's "Stud Tail?" Did you know it's pretty common for unaltered male dogs (and cats) to be missing hair on the base of their tail? It's just another one of the problems when you fail to neuter your dog. You can even avoid some cancers by snip-snip-snipping. Listen Now Purr Therapy A new cafe in Paris offers patrons a dose of stress relief with their coffee. The Cat Cafe has a dozen resident cats to provide "purr therapy." The manager there says a cat's purring has been shown to help relieve arthritis or rheumatism and to lower blood pressure and heart rate. It seems the whole concept is a hit. So many people showed up for the cafe's recent opening that about 300 had to be turned away. Listen Now Read more about this week's show.
Ela já foi da firma, já participou de quase todos os programas daqui e agora, nesse novo formato, está marcando presença mais uma vez! Viih Tube é sucesso onde quer que vá, conquistando todo mundo com seu carisma, autenticidade e uma boa dose de humor.
A convidada de hoje é Ana Furtado, apresentadora, atriz, jornalista e agora youtuber. Ela vive uma nova fase, se declarando "protagonista da própria vida", após superar um dos momentos mais desafiadores de sua vida. Sua trajetória inclui trabalhos como *Vídeo Show, **É de Casa* e o meme *3 reais*. Ana é mãe de Isabella, esposa de Boninho, embaixadora de premiações internacionais e escritora. Para os íntimos, é chamada de "Bia". 5X mais poder de limpeza com Listerine: https://www.amazon.com.br/stores/Listerine/page/0E608208-BB93-423D-800D-C3B32B69F135?CHANNEL=FLOWAMAZON - Com a ajuda do novo Dove Desodorante Creme Sérum, o único que combina a leveza do creme com a potência do sérum, levando skincare para as suas axilas!
Dank der Entdeckung von Joseph Lister sank die Sterblichkeitsrate nach Operationen rapide. Was genau es damit auf sich hat, erzählt Andrea Sawatzki in dieser Folge.
A atração de hoje é INTERNACIONAL. Jade Thirlwall está no PodDelasPodCast Show para compartilhar todos os detalhes sobre seu novo single Angel of My Dreams e divulgar sua carreira solo no Brasil. Durante o bate-papo, ela soltou alguns spoilers e garantiu muitas risadas. Vem assistir _ 5X mais poder de limpeza com Listerine: https://www.amazon.com.br/stores/Listerine/page/0E608208-BB93-423D-800D-C3B32B69F135?CHANNEL=FLOWAMAZON
O convidado de hoje é cantor, compositor e marido! Sim, aos 25 anos ele carrega esse título com orgulho, porque é o maior fã e melhor amigo da sua esposa, a Sasha.Fez música clipe para ela. Ele sabe que ganhou mais notoriedade com seu relacionamento, mas se engana quem acha que ele começou sua carreira artística agora. Ele tem um talento para música desde criança, cantava na igreja, se apresentava na TV bem pequenininho, ele é o João Lucas. 5X mais poder de limpeza com Listerine: https://www.amazon.com.br/stores/Listerine/page/0E608208-BB93-423D-800D-C3B32B69F135?CHANNEL=FLOWAMAZON
Hopestream for parenting kids through drug use and addiction
ABOUT THE EPISODE:After years of producing feature films and TV shows about family life like Cinderella Story, Perfect Man, Lizzy McGuire, and many others, Mark Rosman was forced to face the reality of problems in his own family.Mark and his wife spent some time in denial about their daughter's substance use. Even after two trips to the emergency room, they decided against professional advice to get her into treatment immediately. They chalked everything up to ordinary teen rebellion and experimentation, sending her to a traditional boarding school instead. Less than one month later, she was in the emergency room again after downing a bottle of Listerine. Thus began the roller coaster we're all familiar with: periods of hope and sobriety, followed by lapses into chaos and returns to use.Like many parents, Mark instinctively rejected the notion of "self care", or any form of detachment from his daughter's behavior and state of mind at any given time. Finally, in what seemed like his 100th parent group meeting, he admitted to himself (and everyone else there) the utter hopelessness he was feeling. This was the beginning of the entire family's recovery.In this episode, Mark talks about how this realization helped him to learn to set boundaries and how – now five years into his daughter's recovery – he's making his own story into a feature film which, for the first time, focuses on the experiences of parents.EPISODE RESOURCES:Keep Coming Back FilmKeep Coming Back Instagram accountThis podcast is part of a nonprofit called Hopestream CommunityLearn about The Stream, our private online community for momsLearn about The Woods, our private online community for dadsFind us on Instagram: @hopestreamcommunityDownload a free e-book, Worried Sick: A Compassionate Guide For Parents When Your Teen or Young Adult Child Misuses Drugs and AlcoholHopestream Community is a registered 501(c)3 nonprofit organization and an Amazon Associate. We may make a small commission if you purchase from our links.
Retorno da nossa apresentadora, escritora, astróloga, médium MÁRCIA SENSITIVA! Vamos bater um papo sobre vida, carreira, espiritualidade e muito mais. @marciasensitiva Com a ajuda do novo Dove Desodorante Creme Sérum, o único que combina a leveza do creme com a potência do sérum, levando skincare para as suas axilas!
Miért válnak egyes keresztnevek komikussá, tudnának-e az emberek fotoszintetizálni, szüksége van-e az országnak vallásra, hogyan működik az aeroszolos flakon, milyen szempontok alapján adjátok át a helyeteket a buszon, hol rendezték volna a budapesti olimpián a szörfözést, változtatták-e már meg ország himnuszát, lehetnek-e szerelmesek az állatok, mit csinál egy alkusz cég, utazgasson vagy tanuljon a frissen érettségizett diák, hogy állnak manapság a lézerfegyver fejlesztések, mi értelme a tejfogaknak, miből éltek a hippik, mit gondolunk az Imane Khelif-ügyről, hol nyugszik DJ Palotai, hogyan rendezik sorrendbe a kínai szavakat, ártalmas-e a Listerine, mi történik a tankolás után a tárca és telefon nélküli sofőrrel, miért hasonlít a panda a kardszárnyú delfinre, kötelező-e a magyar csapatnak szurkolni, rosszabbul hallanak-e a karfiolfülü birkózók, Angliában balkéz-szabály van-e, mi a különbség a maximalista és a perfekcionista között, madarakon miért nincs függőleges vezérsík? Zenék: Sweet
“…and today we're talking about the Listerine dad fish. But more on that later.” The bright and colorful coral reefs are home to a wide variety of fish, but very few can be considered decent parents. The yellowhead jawfish is, however, an exception. Taking care of kids is never easy, but try doing it without […]
Glassy, who's a bit touchy about his pearly (or not-so-pearly) whites, braces himself for a wild ride. We chat with Oral Health Therapist Luke Nancarrow to prove (or debunk) this Dumb As Fact. He also shares his top tips for a smile that could blind a dentist.But that's not all! We dig into the rumor that Listerine invented halitosis to sell mouthwash and uncover the gruesome, gag-worthy history of ancient and medieval dentistry.Get ready for laughs, gasps, and a whole lot of dental drama on this hilarious, enlightening and tooth-tingling episode!
In this episode of “How Do You Say That?!” sponsored by britishvoiceover.co.uk, Dutch voice actor Bart Kooiman joins Sam and Mark to talk about the millennial read (and what that even means), a panto documentary, and how some clients don't give you enough information. There's a boy who comes face-to-face with a dragon and a farmer gets an electric shock!Our VO question this week is all about the evolution of language, both Dutch and English.Get involved! Have you got a Wildcard suggestion that we should try or an idea for the show? Send it to us via Mark or Sam's social media or email it directly to podcast@britishvoiceover.co.ukScript 1Pantomimes are full of quick changes and transformations. And the dressers, often poised in the wings, are on hand to help with fastenings and complicated costumes. Zips though can be a nightmare: quick if they run smoothly but disastrous if they stick. There are few things more likely to stress out an actor than the panic of going on stage half dressed.Quick-change costumes are designed so that they can be removed quickly - and rigged so they can be put on quickly… very quickly! Script 2Stressexe is a marketplace where bookings can be bought, sold, and bid on.Here's how…Let's say a guy - call him Craig – makes a reservation.It could be for a barber, or membership of a golf club – or maybe it's for a toy, for his niece.But what happens if Craig can't use his reservation anymore?Maybe he has to work late. Or maybe the sitter has cancelled.Craig's place goes to waste.**Listen to all of our podcasts here - you can also watch on YouTube, or say to your smart speaker "Play How Do You Say That?!"About our guest: Bart Kooiman was born and raised in Amsterdam. His voice clients include brands like Citroën, Head & Shoulders, Heineken, Listerine and the Red Cross. He works primarily in Dutch, but with his Dutch-to-neutral European accent he's booked in English as well.Bart has had a knack for acting since he was a boy. At 13, he did his first voice-over job for Dutch national television, voicing a group of 16 Moldovian foster children. He continued acting on stage through college in both classical and contemporary plays with an independent Amsterdam theatre group.As project manager, Bart found out he loved storytelling. He began his voice acting business in 2019 and discovered it's the best career in the world.Mostly booked for explainers, he loves it most when he can go all the way with crazy acting roles. As one of his clients put it: Bart is like a speech chameleon. He calls himself Dutch voice nerd, because playing with words is what makes him get up every day. Well, that and his 3 kids. Bart's Website @bartkooiman_voiceover on Instagram Bart on YouTubeResources:
This week on the Creator Economy Live Podcast, we have an exciting episode featuring Brendan and Keith, with a special guest appearance by Matt Fantazier, who runs Integrated Media at Kenvue. For those unfamiliar, Kenvue is the new consumer business spun off from Johnson & Johnson, and it includes household brands like Neutrogena, Tylenol, and Listerine. Matt shares his journey through the major transition from J&J to Kenvue, his experiences in integrated media, and the evolving role of creators in today's brand ecosystems. Discover how influencer marketing has shifted from mere explanations to becoming a crucial part of brand strategies. Before we dive into our conversation with Matt, Brendan and Keith break down the top stories in the industry, including Meta's NewFronts push, TikTok's premium ad options, and the significant rise in CTV advertising.
Lynn Power spent much of her 30 year career running and transforming agency brands. Lynn has expertise in transforming organizations from top to bottom – including capabilities, organizational structure, talent and culture. She recently left the big agency world to launch two brands: MASAMI, a premium clean haircare brand which launched in February 2020 and Isle de Nature, bee-powered home fragrance which launched in September 2020. After battling breast cancer in 2021, she launched the Conscious Beauty Collective in 2022. Prior to her entrepreneurial move, Lynn was CEO of J. Walter Thompson NY, responsible for the flagship office of WPP's $1.5B iconic agency (the oldest advertising agency in the world). Throughout her career, Lynn has had the great fortune of working on some of the world's most well-known brands including: LISTERINE, American Express, Clinique, Hershey's, Pizza Hut and Wild Turkey. Lynn believes that business success relies on building a team that respects and nurtures ideas as well as the people who create them. She believes in moving at the speed of culture, eliminating barriers and helping women find their voices. Lynn PowerCo-Founder & CEO, MASAMI lynn@lovemasami.com 917-209-0799 lovemasami.com @lynnpowered @lovemasamihair #masami #consciousbeauty #lovemasami #isledenature #toxic #EU #standards #cleanbeauty #skincare #greenbeauty #naturalskincare #beauty #crueltyfree #skincareroutine #naturalbeauty #vegan #selfcare #organicskincare #healthyskin #natural #glowingskin #cleanskincare #veganbeauty #organicbeauty #makeup #organic #veganskincare #skincareproducts #nontoxicbeauty #skincaretips #crueltyfreebeauty #skin #antiaging #wellness #cosmetics #nontoxic #plantbased FIND DAWN HERE: Email: dawnversations@gmail https://www.podpage.com/dawnversations/ https://www.youtube.com/channel/UCGZFdplRZmXIguI31KbX2eg https://podcasts.apple.com/us/podcast/dawnversations/id1611645700 https://open.spotify.com/show/3nyVFDlLJ0y7S2MQ0ZqiZ5?si=RFLLwSTYQVGta30nkZ2vsg https://www.pandora.com/podcast/dawnversations/PC:1000700495 https://www.facebook.com/dawnversations.2024 https://www.instagram.com/dawnversations_podcast/ https://www.pinterest.com/dawnwecker12/dawnversations-podcast/ https://www.tiktok.com/@dawnversations Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/francesco-dandrea/a-day-late-and-a-dollar-short License code: EYUYKNS4AFNOD1JO #follow #like #subscribe #pin #share #podcast #apple #spotify #anchorfm #google #amazon #iheartradio #tiktok #facebook #pinterest #instagram #youtube #life #dawnversations #dawnversationspodcast --- Send in a voice message: https://podcasters.spotify.com/pod/show/dawn9792/message
88%+ are deficient in this single molecule which helps with neurotransmitters, cardiovascular health, lowering inflammation, metabolism, erections / sexual function, energy and MANY more important functions inside the human body. This molecule is gas called nitric oxide. Nitric oxide (NO) is a molecule that plays a crucial role in various physiological processes in the human body, including inflammation. It is a gaseous signaling molecule that acts as a vasodilator, meaning it helps to relax and widen blood vessels. When the blood vessels widen it allows oxygen and nutrients to EVERY cell inside the body. Nitric oxide is produced by various cells, including endothelial cells (cells lining blood vessels), immune system (macrophages), and brain cells (neurons). Controls mitochondria and telomeres. It helps your body recover from injury and workouts. It's been called the holy grail of anti-aging medicine. Nitric oxide can also have anti-inflammatory effects. It can modulate the immune response by inhibiting the production of pro-inflammatory cytokines and chemokines. Additionally, nitric oxide can regulate the activity of immune cells, such as T cells and neutrophils, to prevent excessive inflammation and tissue damage. In 1992 the journal of science called it the molecule of the year It's how cells communicate with each other. Imagine if you are trying to call your best friend to warn them about an intruder coming to their house, but your communication lines have been cut. Things will go wrong! The most common symptoms of nitric oxide deficiency include High blood pressure Erectile dysfunction Cardiovascular disease Alzeihmers Dementia Insulin resistance Type 2 diabetes Weight Gain Why are so many people nitric oxide deficient? Let's get into the top 6 causes of low nitric oxide levels and the solutions for each… Antiseptic Mouthwash (Scope, Listerine, etc) and Fluoride toothpaste - Dr Nathan Bryan has published research showing when you use mouthwash it kills the oral microbiome that responsible for making nitric oxide, your blood pressure goes up and you develop erectile dysfunction. This dramatic decrease in NO levels happens within days of using mouthwash. Swap to essential oils. My go to toothpaste is Revitin (see link below), and my go to mouthwash is from Doterra (link below) A diet high in carbohydrates will raise high blood sugar levels leading to glycation of nitric oxide synthase enzyme - A better diet would be low carb, keto and fasting. The 10 best foods for nitric oxide are …. Leafy greens: Vegetables like spinach, kale, arugula, and Swiss chard are high in nitrates, which are converted into nitric oxide in the body. These greens also contain other beneficial nutrients like vitamins C and K, which support overall vascular health. Beets: Beets and beetroot juice are well-known for their high nitrate content. Consuming beets can help increase nitric oxide production and improve blood flow, potentially enhancing exercise performance and cardiovascular health. Garlic: Garlic contains allicin, a compound that can stimulate nitric oxide production and help relax blood vessels. Incorporating garlic into your diet, whether raw or cooked, can be beneficial for cardiovascular health. Citrus fruits: Fruits like oranges, lemons, and grapefruits are rich in vitamin C, which is a cofactor for the enzyme that produces nitric oxide. Including citrus fruits in your diet can support nitric oxide synthesis and promote vascular health. Pomegranate: Pomegranates are packed with antioxidants, including polyphenols, which have been shown to enhance nitric oxide production and improve endothelial function. Nuts and seeds: Almonds, walnuts, flaxseeds, and chia seeds are good sources of arginine, an amino acid that serves as a precursor to nitric oxide synthesis. These foods can help boost nitric oxide levels in the body. Dark chocolate: High-quality dark chocolate with a cocoa content of at least 70% or more contains flavonoids that promote nitric oxide production and improve blood flow. Enjoying moderate amounts of dark chocolate can have cardiovascular benefits. Watermelon: Watermelon is rich in citrulline, an amino acid that converts to arginine in the body, thus supporting nitric oxide production and vascular health. Fish: Fatty fish like salmon, mackerel, and trout are good sources of omega-3 fatty acids, which have anti-inflammatory properties and can improve endothelial function, indirectly supporting nitric oxide production. Green tea: Green tea contains catechins, polyphenolic compounds that have been shown to enhance nitric oxide production and improve vascular function. Proton pump inhibitors Antacids - in 2015 studies showed that people on PPI's for 3-5 years have a 35% higher incidence in heart attack or strokes because of what it does to shut down nitric oxide. They are extremely dangerous long term. If you are dealing with heartburn, most of the time it's NOT a problem of too much acid, it's a problem with too little and the LES (lower esophageal spincter) is not functioning well. Getting into a parasympathetic state before eating can help, humming ( Humming also helps with NO. When you hum you produce nasal NO) and gratitude before eating helps, also adding 1 tablespoon of acv before meals. Mouth breathing - Nitric oxide is released in the nasal airways in humans when you breathe through your nostrils. When you primarily breath through your mouth, it prevents NO from being produced. Focus on nostril breathing throughout the day, and mouth tape at night. I personally use Somnifix, I will drop a link below for them. Sedentary lifestyle - Yo've heard sitting is the new smoking, it's true. If you don't use it, you lose it. Get 10k steps per day, and the best exercises for NO are sprinting, strength training, bonus points if you do it outside getting sunshine. Also, a good general protocol is 20-30 minutes of aerobic exercise 2-3 times per week. Statins disrupt lipid rafts and cell signaling and mitochondria. When you lower your cholesterol below 200, it blocks nitric oxide from binding to the cell receptors. Cholesterol is not the boogeyman , it is vital for liver and hormone health. But the statin industry made 15.4 billion last year so why would they want you to know this? Your cell membrane is made of cholesterol! Lastly, nitric oxide supplementation can help. My go to are NO2U lozenges from Dr Nathan Bryan. Link and coupon code can be found below. Resources mentioned: Somnifix Mouth Tape Affiliate Link: https://www.somnifix.com/?rfsn=3778298.e05929&utm_source=refersion&utm_medium=affiliate&utm_campaign=3778298.e05929 Nitric Oxide Lozenges N1O1: https://n1o1.com/?sld=ketokamp use code KETOKAMP Revitin Fluoride Free Toothpaste: https://revelationhealth.com/products/revitin/azadi?afmc=azadi Essential Oils Mouthwash On Guard: https://www.doterra.com/US/en/site/ketokamp / / E P I S O D E S P ON S O R S ⭐ Bioptimizers Magnesium Breakthrough. Get the best night of sleep ever. NO OTHER supplement on the market offers 7 types of magnesium in 1 bottle. Visit bioptimizers.com/ketokamp and use promo code ketokamp10 for 10% off your first order. ⭐ Upgraded Formulas | http://www.upgradedformulas.com Purchase Upgraded Formulas, Charge Electrolytes, and other products. GET 15% OFF with Coupon Code: KETOSIS Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. Some links are affiliate links // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸ tiktok | @thebenazadi https://www.tiktok.com/@thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
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Children's Oral Health Month: Emphasis on Children's Dental Care By Heather Hakes, RDH Original article published on Today's RDH: https://www.todaysrdh.com/childrens-oral-health-month-emphasis-on-childrens-dental-care/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Oil Pulling: Is It Worth the Effort? By Brooke Sergent, RDH, BS Original article published on Today's RDH: https://www.todaysrdh.com/oil-pulling-is-it-worth-the-effort/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Incorporating the Five Love Languages into Dentistry By Angela Grover, RDH, BASDH Original article published on Today's RDH: https://www.todaysrdh.com/incorporating-the-five-love-languages-into-dentistry/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Functional Medicine: Antimicrobials Should Treat Causes of Perio, Not Just Symptoms By Jenna Arcaro, RDH Original article published on Today's RDH: https://www.todaysrdh.com/functional-medicine-antimicrobials-should-treat-causes-of-perio-not-just-symptoms/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Dental Hygienist's Letter: I Am Qualified to Provide Care for Patients By Brooke Sergent, RDH, BS Original article published on Today's RDH: https://www.todaysrdh.com/a-dental-hygienists-letter-i-am-qualified-to-provide-care-for-you/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Vitamin Deficiencies: Noting the Oral Health Clues Present in the Mouth By Heather Hakes, RDH Original article published on Today's RDH: https://www.todaysrdh.com/vitamin-deficiencies-noting-the-oral-health-clues-present-in-the-mouth/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Patient Relationships: Empathy Fosters Trust and Treatment Acceptance By Suzanne L. Vila, RDH Original article published on Today's RDH: https://www.todaysrdh.com/patient-relationships-empathy-fosters-trust-and-treatment-acceptance/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Dental Ethics: A Decision-making Framework Helps Define Solutions By Stacie Neely, RDH, BSDH Original article published on Today's RDH: https://www.todaysrdh.com/dental-ethics-a-decision-making-framework-helps-define-solutions/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
5 Things to Know about HIPAA When Patients Request Dental Records By Spring Hatfield, RDH, BSPH Original article published on Today's RDH: https://www.todaysrdh.com/5-things-to-know-about-hipaa-when-patients-request-dental-records/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Seasonality of Immune Response: Could Gingival Inflammation Have a Seasonal Component? By Spring Hatfield, RDH, BSPH Original article published on Today's RDH: https://www.todaysrdh.com/seasonality-of-immune-response-could-gingival-inflammation-have-a-seasonal-component/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Hygiene, Heart, and Leadership: Transforming Dental Office Culture By Cara Reck, BS, RDH, LAP, FADHA Original article published on Today's RDH: https://www.todaysrdh.com/hygiene-heart-and-leadership-transforming-dental-office-culture/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Appreciation in the Dental Workplace Part Two: The 5 Languages of Appreciation By Corina Hartley, RDH Original article published on Today's RDH: https://www.todaysrdh.com/appreciation-in-the-dental-workplace-part-two-the-5-languages-of-appreciation/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrisnse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Kicking off 2024 with a look back at some beauties that came before, so that we may steel our resolve for the reviews and comedy that will come in the future. This is the calm before the storm! Comedy storm! AHHHH!! We got little treats from episodes 36-56, a fat stack, including a Seinfeld review from episode 36, a review for White Sands National Park from episode 39, a tripod chair from 42, A Statue of a Monkey with a Beer and a lost segment from episode 44, an Ewok movie double pack from 47, a look at the """Original""" Tamagotchi from 51, and a Listerine review from big episode 56. Want more party? Check it out at https://www.reviewpartydotcom.com/ !
Appreciation in the Dental Workplace Part 3: Discovering Your Appreciation Languages By Corina Hartley, RDH Original article published on Today's RDH: https://www.todaysrdh.com/appreciation-in-the-dental-workplace-part-3-discovering-your-appreciation-languages/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrinse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Appreciation in the Dental Workplace Part One: Retaining Staff By Corina Hartley, RDH Original article published on Today's RDH: https://www.todaysrdh.com/appreciation-in-the-dental-workplace-part-one-retaining-staff/ This audio article is sponsored* by LISTERINE®. Although LISTERINE® Antiseptic is the most extensively tested over-the-counter mouthrisnse in the world, with over 30 long-term clinical trials examining its safety and efficacy, there is still some misinformation out there over the uses of mouthrinses containing alcohol. To help understand the safety of alcohol-containing mouthrinses, in case any patients ask you about it, head on over to https://rdh.tv/ListerineSafety Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
You might not know the name Baltimora, but you have almost certainly encountered the anthemic “Tarzan Boy” in unexpected places. From iconic Listerine commercials to grand wrestling entrances, this unforgettable 80s song continues to live on decades after this Italian music project burst onto the scene. This week, we're joined by Jim Logrando to unravel the mystery of who actually sang the song, the fascinating concept of the “millennial whoop”, and the biggest question of all: is there any need to swing further into the jungle of Baltimora's back catalog? Stay tuned to find out. If you like the show, be sure to rate, review, and subscribe. Email us at onehitthunderpodcast@gmail.com. Also, follow us on our social media: Twitter: @1hitthunderpod Instagram: onehitthunderpodcast Wanna create your own podcast? Contact us at We Know Podcasting for more information. Visit Punchline: A Band Called Punchline | Pittsburgh, PA for Punchline tour dates, news, and merch. Sign up for more One Hit Thunder on our Patreon One Hit Thunder | Patreon Learn more about your ad choices. Visit megaphone.fm/adchoices
The queens get stuffed as they rehash Thanksgivings past. No poetry, but this episode does make hilarity rhyme with vulgarity. After all, a Breaking Form Thanksgiving special wouldn't be complete without talk of clitoris, lesbian octogenarians, and Listerine cocktails. Unbuckle your seatbelts and your pants, cuz this is a messy wild ride -- definitely not for the feint of heart!
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Another weekend where rain played a factor in everyones racing plans. The Fall Final got moved to the end of October ruining our live show and postponing that until that weekend. We sent Brad and Amanda down to Stafford for the weekly show Friday where they sat down with TTMG and the Mad Pup George Bessette JrSupport the show
In this edition of Yes, Trend Even Abs!, Jack and Miles discuss people boning in SF Robotaxis IMMEDIATELY, a homophobic boycott alert (Listerine this time), Ivanna Trump's gravesite (on a golf course), and Rudy Giuliani's legal woes! WATCH: Fitness Made SimpleSee omnystudio.com/listener for privacy information.
Your oral microbiome is just as important as your gut microbiome. Your oral microbiome is linked to your digestion, immunity, nutrient absorption, cardiovascular health, and so much more. This means, when we use products that disrupt our oral microbiome, we also disrupt our countless other systems of the body. Mouthwash happens to be one of these products. It may leave your mouth with a minty fresh scent, but it's also killing the bacteria that are trying to keep your teeth and gums healthy. You know that cool mint Listerine that looks cool and minty? It contains dye green number three, which has been linked to bladder cancer. And then the original Scope contained yellow number five made from a derivative of coal tar. And blue number one has been connected to cancer in many of the animal tests that have been done. This is why in today's episode, we are going to explore solutions for the Fatal Convenience: Mouthwash. What I discuss: 00:14: What are the dangers of mouthwash? 05:16: What can you use instead of mouthwash to protect your microbiome? More links: Shop Methodology at https://www.gomethodology.com/ and use the code DARIN at checkout. Shop Aquatru at https://aquatruwater.com/?oid=2&affid=95&c=darinolien to save $100. Find more from Darin: Website: https://darinolien.com/ Instagram: https://www.instagram.com/Darinolien/ Book: https://darinolien.com/fatal-conveniences-book/ Down to Earth: https://darinolien.com/down-to-earth/