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Mike Renner, Kyle Long, and JP Acosta review the Chiefs-Jaguars Monday Night Football bonanza. Then they cut on the tape to hit the trenches, breakdown the plays and report on the rookies before finishing up with deeper week four insights upon further review. Intro (0:00) KC-JAX (0:11) Trench Takes (18:57) JPs Playbook (27:24) Renner's Rookie Report (39:22) Upon Further Review (48:05) Pushing the Pile is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts. Subscribe to our YouTube channel: https://www.youtube.com/@pushingthepile Download and Follow Pushing the Pile on Spotify: https://open.spotify.com/show/2RFkEgdbFxbPBDU5F5xEjJ?si=1062d40c04e24fd5 Follow our PTP team on Twitter: @mikerenner_, @Ky1eLong, @acosta32_jp, @pushingthepile Sign up for the Pick Six Newsletter at https://www.cbssports.com/newsletters For more NFL coverage from CBS Sports, visit https://www.cbssports.com/nfl/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ Visit the betting arena on CBSSports.com for all the latest sportsbook reviews and sportsbook promos. You can listen to Pushing the Pile on your smart speakers! Simply say "Alexa, play the latest episode of the Pushing the Pile podcast" or "Hey Google, play the latest episode of the Pushing the Pile podcast." To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Join us today on the No Grey Areas Podcast with Lead Pastor and author of The Heaven Project book set, Trent Renner! He sits down to answer and ponder on some of the biggest and most controversial questions society has wrestled with for decades. Questions like: Can we really trust the Bible? How do I know that God exists? Why do good things happen to good people? Trent dives into these deep questions while exploring cultural contradictions, spiritual mysteries, and timeless truths that can transform the way we see life and faith.In this episode, Trent addresses bold topics — including the Charlie Kirk incident and the state of our world today. He talks about the persecution of faith, what it means to follow Jesus in a divided culture, and whether society is “crucifying Jesus” in modern times.This conversation is for anyone curious about God, seeking deeper understanding, and ready to wrestle with challenging questions. Be sure to like or comment below if you loved this episode! If you want to learn more or get connected with Trent Renner, visit his website at https://trentrenner.com/homeWEBSITE: https://www.nogreyareaspodcast.com/INSTAGRAM: https://www.instagram.com/nogreyareas_gagliano/FACEBOOK: https://www.facebook.com/NoGreyAreasTIK TOK: https://www.tiktok.com/@nogreyareasgaglianoEMAIL: info@nogreyareas.comYOUTUBE: https://www.youtube.com/channel/UCbnC2rjEumGJhqy54qazFFwNo Grey Areas is a motivational podcast with captivating guests centered around how our choices humanize, empower, and define who we become. This podcast is inspired by the cautionary tale, No Grey Areas, written by Joseph Gagliano. Learn more about the truth behind his story involved with sports' biggest scandal at https://www.nogreyareas.com/
Former Florida Speaker of the House and Republican Gubernatorial Candidate Paul Renner joins us!
Subscribe to our BRAND NEW YouTube channel: https://www.youtube.com/@pushingthepile Mike Renner, Kyle Long, and JP Acosta review the MNF doubleheader. Then they cut on the tape to hit the trenches, breakdown the plays and report on the rookies before finishing up with deeper week three insights upon further review. Intro (0:00) Bad Bunny to Play Super Bowl (:50) NYJ-MIA (4:28) CIN-DEN (13:31) Trench Takes (20:05) JPs Playbook (28:20) Renner's Rookie Report (53:26) Fixing Eagles Offense (1:05:45) Metlife Turf (1:13:20) QB Rehab (1:19:11) Kyle's Locks (1:24:34) Pushing the Pile is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts. Subscribe to our YouTube channel: https://www.youtube.com/@pushingthepile Download and Follow Pushing the Pile on Spotify: https://open.spotify.com/show/2RFkEgdbFxbPBDU5F5xEjJ?si=1062d40c04e24fd5 Follow our PTP team on Twitter: @mikerenner_, @Ky1eLong, @acosta32_jp, @pushingthepile Sign up for the Pick Six Newsletter at https://www.cbssports.com/newsletters For more NFL coverage from CBS Sports, visit https://www.cbssports.com/nfl/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ Visit the betting arena on CBSSports.com for all the latest sportsbook reviews and sportsbook promos. You can listen to Pushing the Pile on your smart speakers! Simply say "Alexa, play the latest episode of the Pushing the Pile podcast" or "Hey Google, play the latest episode of the Pushing the Pile podcast." To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Viele der größten Namen des Rock'n'Roll musste unterschiedliche Phasen in ihrer Karriere durchlaufen. Einige davon schafften nach langer Durststrecke beeindruckende Comebacks. Musikradio360 befasst sich heute unter anderem mit Elvis, Tina Turner oder Iron Maiden.
Mike Renner, Kyle Long, and JP Acosta review the high-scoring Lions-Ravens MNF game. Then they cut on the tape to hit the trenches, breakdown the plays and report on the rookies before finishing up with deeper week three insights upon further review. Intro (0:00) DET-BAL (0:21) Trench Takes (10:14) JPs Playbook (23:36) Renner's Rookie Report (36:23) Bears Offense? (44:16) AFC is Wild West (49:46) Mobile QBs (53:40) Pushing the Pile is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts. Subscribe to our YouTube channel: https://www.youtube.com/@NFLonCBS Download and Follow Pushing the Pile on Spotify: https://open.spotify.com/show/2RFkEgdbFxbPBDU5F5xEjJ?si=1062d40c04e24fd5 Follow our PTP team on Twitter: @mikerenner_, @Ky1eLong, @acosta32_jp, @pushingthepile Sign up for the Pick Six Newsletter at https://www.cbssports.com/newsletters For more NFL coverage from CBS Sports, visit https://www.cbssports.com/nfl/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ Visit the betting arena on CBSSports.com for all the latest sportsbook reviews and sportsbook promos. You can listen to Pushing the Pile on your smart speakers! Simply say "Alexa, play the latest episode of the Pushing the Pile podcast" or "Hey Google, play the latest episode of the Pushing the Pile podcast." To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
It was a disappointing Saturday for the Tar Heels as they fell to UCF in Orlando...Bryn Renner joins to discuss the game and where Carolina goes from here (3:31)Tar Heel rookie Caleb Wilson joins for an awesome interview (25:45)Plus: Olympic Sports update (45:42), Pod anniversary (50:27) and ACC FB scheduling news (51:26)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nicht jede Band prägte drei Jahrzehnte Musikgeschichte und erfand sich dabei gleich mehrfach neu. Die Bee Gees können aber genau das von sich behaupten. Musikradio360 erforscht ihre Historie.
30 lange Jahre, von 1891 bis 1921, leitete das sogenannte Erfurter Programm die Sozialdemokratische Partei Deutschlands. Das ihm nachfolgende Görlitzer Programm hingegen wurde bereits nach vier Jahren wieder durch ein neues ersetzt, das nach dem dort im September 1925 stattfindenden Parteitag Heidelberger Programm hieß – und stolze 34 Jahre die Grundsätze der SPD definieren sollte, bis es 1959 durch das berühmte Godesberger Programm abgelöst wurde. Weshalb nach nur vier diese Neuausrichtung und worin bestand sie? Dies erläuterte in der Parteizeitung Hamburger Echo vom 20. September ein Autor, dessen Wort in der internationalen Sozialdemokratie bereits damals Gewicht hatte, der zu allerhöchsten Ämtern allerdings erst nach dem Zweiten Weltkrieg aufstieg: Karl Renner, in den 1920er Jahren Abgeordneter zum Nationalrat in Wien, wurde 1945 zum ersten Bundespräsidenten der zweiten österreichischen Republik gewählt. Wie er zwanzig Jahre zuvor die neue Programmschrift der deutschen Schwesterpartei bewertete, weiß Frank Riede.
Die Verkehrsminister der Bundesländer beraten über eine Preiserhöhung des Deutschlandtickets. Oliver Wittke vom Verkehrsverbundes Rhein-Ruhr sprach sich dafür aus, die ansteigenden Kosten fair zu verteilen. Das Ticket sei „ein echter Renner“. Meurer, Friedbert www.deutschlandfunk.de, Interviews
Mike Renner, Kyle Long, JP Acosta and guest host Ben DiNucci review the Monday Night Football doubleheader. Then they cut on the tape to hit the trenches, breakdown the plays and report on the rookies before finishing up with deeper week two insights upon further review. Intro (0:00) Buccaneers-Texans (1:06) Chargers-Raiders (13:18) Trench Takes (26:53) JP's Playbook (40:53) Renner's Rookie Report (54:23) Upon Further Review (1:04:50) Pushing the Pile is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts. Subscribe to our YouTube channel: https://www.youtube.com/@NFLonCBS Download and Follow Pushing the Pile on Spotify: https://open.spotify.com/show/2RFkEgdbFxbPBDU5F5xEjJ?si=1062d40c04e24fd5 Follow our PTP team on Twitter: @mikerenner_, @Ky1eLong, @acosta32_jp, @pushingthepile Sign up for the Pick Six Newsletter at https://www.cbssports.com/newsletters For more NFL coverage from CBS Sports, visit https://www.cbssports.com/nfl/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ Visit the betting arena on CBSSports.com for all the latest sportsbook reviews and sportsbook promos. You can listen to Pushing the Pile on your smart speakers! Simply say "Alexa, play the latest episode of the Pushing the Pile podcast" or "Hey Google, play the latest episode of the Pushing the Pile podcast." To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
16 Set. 25 - Ibovespa Recorde e Renner +4%Olá, sejam bem-vindo a mais um Fechamento de Mercado, comigo Flávio e Ricardo, hoje é 3a. feira, dia 16 de setembro, e o programa de hoje é dedicado aos 2 mil investidores que já assistiram o Mata-Mata “Qual Ação de Transmissora Comprar? ISAE4, TAEE11 e ALUPAR e a escolhida pode subir 37% até dezembro de 2026, 15 meses, e mais 5% em dividendos, 42% no total. Se vc não assistiu, vá lá e assista porque está imperdívelO Ibovespa subiu mais, +0,36% e bateu recorde de fechamento, aos 144,061 pontos, mas volume melhor de R$ 21,5 bi, R$ 4,5 bi acima de ontem. O real se valorizou frente ao dólar, de novo, pois a moeda norte-americana caiu -0,43%, a R$ 5,298 x R$ 5,31 de ontem. O dólar irá para R$ 5,25 em outubro, R$ 5,20 em novembro e R$ 5,15 em dezembro, podendo ir até mais para baixo. Os juros longos, como era de se esperar, caíram com o Tesouro Prefixado 2032 para 13,48% de 13,56% ao ano, ontem, e o IPCA+ 2029 estabilizou em 7,64%.Veja recomendações de compra de ações do Conde e Ricardo no vídeo de Fechamento de hoje.
Deze week bespreken Thijs & Geert weer wat er zich afspeelt achter de schermen bij BEAT Cycling Club. Met deze week: hoe belangrijk data is geworden voor de scouting, wat we mogen verwachten van de nieuwe renners voor volgend jaar, de mooie week die eraan komt, hoe BEAT omgaat met doping én een (mogelijke) nieuwe Deense renner.Wil je nog meer van dit soort behind-the-scenes? Thijs stuurt elke week een update naar het gratis BEAT Peloton. Wil je direct lid worden en een mooie BBB x BEAT-racebril ontvangen? Meld je dan hier aan en mis niks: https://www.beatcyclingclub.com/pages/meedoen-keuzemenuWil je ook bij de BEAT x Super Cycling Sunday aanwezig zijn en samen met medewielerfanaten genieten van het WK én een live podcast van In de Waaier? Meld je dan hier aan voor de BEAT x Super Cycling Sunday: https://beatcycling.shop/products/ticket-beat-x-super-cycling-sunday?_pos=1&_sid=61662b7f9&_ss=r
Carolina smothered Richmond on the way to its second straight win...Bryn Renner joins to talk the Tar Heel victory (2:30)New Tar Heel wing Jonathan Powell joins (30:36)Plus: HCYJT (22:04), Olympic Sports update (46:47), an ACC ref abruptly quits (50:43) & there is no stopping Jones' fake award (56:35) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
14. september 2025 - Gleden som renner over - Haakon Lie
✅ Work with Sumi 1-on-1 (Main Link):
1995 war die Welt des harten Rock im Wandel: Hair Metal und Grunge waren passé, Stoner Rock wurde zum Trend der Stunde. Und die Welt, na ja, die war 1995 in einem ähnlich tragischen Zustand wie heute.
Renner tries replacing Damon Ultimatum: 00:00 Legacy: 59:11 Patreon YouTube
Prepare-se para uma verdadeira aula sobre o universo da moda circular! Hoje, no Programa de Quinta, lançamos um episódio imperdível que vai desvendar o que realmente falta para a indústria da moda abraçar de vez a circularidade. E para nos guiar nessa jornada, convidamos ninguém menos que Agustina Comas, uma autoridade em moda circular e upcycling.Agustina, é uma visionária que desde 2008 pesquisa e desenvolve soluções inovadoras para a sustentabilidade. Palestrante, consultora e mentora, ela tem como foco disseminar a mentalidade da circularidade nas empresas de moda, mostrando como é possível implementar e sistematizar o upcycling nos processos produtivos. Idealizadora do Sistema de Upcycling Raíz e do Método Comas, ela é a mente por trás da criação de novos produtos a partir de resíduos têxteis, além de ter desenvolvido os inovadores tecidos ORICLA® e ORICLA® ELÁSTICO. Em 2023, sua collab com a Renner, transformando sobras de jeans em peças exclusivas, foi um marco. Seu trabalho já foi reconhecido com prêmios como o Fashion Futures do Instituto C&A Brasil e o Muda na Categoria Moda da Vogue e Sistema B.Não perca essa conversa esclarecedora que irá mudar sua forma de ver a circularidade!
MARCELLIN LIVE Interview with Josh Renner by Ralph Barba
Mike Renner, Kyle Long and JP Acosta review a wild Monday Night Football 4th quarter comeback. Then they cut on the tape to hit the trenches, breakdown the plays and report on the rookies before finishing up with deeper week one insights upon further review. Intro (0:00) MNF Review (0:27) Trench Takes (20:27) JPs Playbook (24:15) Renner's Rookie Report (33:49) Upon Further Review (44:09) Pushing the Pile is available for free on the Audacy app as well as Apple Podcasts, Spotify and wherever else you listen to podcasts. Subscribe to our YouTube channel: https://www.youtube.com/@NFLonCBS Download and Follow Pushing the Pile on Spotify: https://open.spotify.com/show/2RFkEgdbFxbPBDU5F5xEjJ?si=1062d40c04e24fd5 Follow our PTP team on Twitter: @mikerenner_, @Ky1eLong, @acosta32_jp, @pushingthepile Sign up for the Pick Six Newsletter at https://www.cbssports.com/newsletters For more NFL coverage from CBS Sports, visit https://www.cbssports.com/nfl/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ Visit the betting arena on CBSSports.com for all the latest sportsbook reviews and sportsbook promos. You can listen to Pushing the Pile on your smart speakers! Simply say "Alexa, play the latest episode of the Pushing the Pile podcast" or "Hey Google, play the latest episode of the Pushing the Pile podcast." To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Meurer, Friedbert; Renner, Martina www.deutschlandfunk.de, Informationen am Mittag
Meurer, Friedbert; Renner, Martina www.deutschlandfunk.de, Informationen am Mittag
Anna Renner hat unzählige Stunden mit großen Haien verbracht. Über vier Jahre lang leitete sie ein Hai-Tauchboot am berühmten Tiger Beach auf den Bahamas – einem der besten Orte weltweit, um Tigerhaie und andere faszinierende Arten hautnah zu erleben.Als Verhaltensbiologin berichtet Anna von außergewöhnlichen Begegnungen, wissenschaftlichen Beobachtungen und Momenten, die nur entstehen, wenn man diesen majestätischen Tieren auf Augenhöhe begegnet.Heute ist Anna Teil des Ocean Collective und engagiert sich im europäischen Haischutz an der „Küste der Hoffnung“.Wir sprechen aber auch über Herausforderungen, die man vielleicht nicht sofort mit Haien verbindet – wie Sexismus in der Tauchbranche – und warum es so wichtig ist, dass sich hier etwas verändert.Wie im Podcast angesprochen, habe ich folgende Empfehlungen zum Thema Seximus für euch:Podcast: „Die Alltagsfeministinnen“ – heisst seit ein paar Folgen „Ein Zimmer für uns Allein“.Buchtipps: - Unlearn Patriarchy- Das Buch, das jeder Mann lesen sollte: In 4 Schritten zum Feministen- Das Ende der Ehe: Für eine Revolution der Liebe- Unsichtbare FrauenFalls Du Lust hast, mit Anna Haien zu begegnen oder von ihr das Freitauchen zu lernen, findest du Infos hier: www.ocean-collective.deMit „Ein Leben für den Ozean“ ist ein Buch zum Podcast erschienen. Es erzählt 10 Geschichten über die Held*innen der Meere und begeistert bildgewaltig für den Ozean. Ihr könnt es unter www.ein-leben-fuer-den-ozean.de bestellen.Den Link zu meinen Werbepartnern findest du hier: https://linktr.ee/helden_der_meere_partner
Die Heiterkeit hat eins der interessantesten deutschen Alben des Jahres produziert. Musik, die sich mit schwierigen Themen befasst aber trotzdem Trost spendet. Höchste Zeit, dass Musikradio360 mal genauer hingehört hat.
Paul Renner, former Speaker of the Florida House of Representatives, has entered the race to be Florida Governor. He joins JMN to share focal points of his campaign. Renner will campaign against Trump-backed Republican candidate Byron Donalds. The general election is in November 2026.
Joyce talks about Senator Elizabeth Warren and Health Secretary RFK JR get into about vaccines at the Senate hearing.Could Governor Gavin Newsome be the Democratic pick? It sure seems like it. Traditional values winning right now, too many anti-American people in America, H1B Visa and Outsourcing Workers, Mayor Scott Singers office pens a response correct misinformation about the "bulldozing" of a war memorial park in Boca and Former House Speaker Paul Renner joins to show to talk about traditional values, working with Governor DeSantis, his experience in politics and why he is a great choice for the next Governor of Florida. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Paul Renner announced that he is a GOP candidate for Florida Governor in 2026. As a member of the University System Board of Governors, Renner opposed the candidacy of Dr. Santa Ono as President of the University of Florida. The first time a candidate that was approved by the University's Regents was not approved by the Board of Governors. Renner's term as Speaker of The House led to insurance reform, leading to stabilized homeowners insurance rates and declining auto rates. Renner presided over the rejection of DEI in Florida, the Florida heartbeat pro-life bill, universal school choice, data privacy protections, and limits on social media access by children.
Brittany Renner had a public altercation with her ex-partner, PJ Washington, during a child custody exchange. The incident, which was captured on video, shows Renner confronting Washington, leading to a heated exchange. Renner later shared the footage online, sparking discussions about co-parenting dynamics. See omnystudio.com/listener for privacy information.
In the final hour, Mac & Bone are joined by former Tar Heel QB Bryn Renner, who tries to find the positives in UNC's blowout loss last night to TCU, Ashley Stroehlein stops by to talk about the state of the Panthers WR room after moves made last week, they read funny texts, preview the night in sports, & moreSee omnystudio.com/listener for privacy information.
Former Tar Heel QB, and current radio analyst, Bryn Renner joins the show, as he tries to find the positives in UNC's loss to TCU, he gives you his thoughts on why the offense struggled as much as it did, what to make of the same defensive struggles under Bill Belichick, & more See omnystudio.com/listener for privacy information.
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Support the showTrykk linken over "Support the show".Dette er link til patreon for deg som ønsker mere av Synseligaen på øret.På Patreon kommer det fullverdig episode hver uke. Medlemskap på Patreon kan benyttes mnd til mnd eller et år av gangen ved ønske.Patreon kan linkes opp mot eks Apple eller Spotify sin Rss link (pod link).(Lydklipp er godkjent av utvalgte spillere & mediahus).Takk til Tv2 sporten & Europort for bruk av lydklipp i denne episoden.
Kürzlich verstarb Alfred Hilsberg, der Gründer des legendären Plattenfirma Zick Zack, die entscheidenden Anteil an der Entstehung der Neuen Deutschen Welle hatte. Musikradio360 schaut auf eine Geschichte voller innovativer Musik und finanziellem Chaos.
1975 war das Jahr, in dem Disco immer größere Erfolge feierte, der Classic Rock in seiner Blüte stand und Punk hinter der nächsten Ecke lauerte. Musikradio360 geht auf Erkundungsreise.
Mit Bands wie Primal Fear, Sinner oder Voodoo Circle hat der Gitarrist Alex Beyrodt die Hard Rock- und Heavy Metal-Fans begeistert. Bei Musikradio360 spricht er über seine Karriere, seine neuen Projekte und die SV Elversberg.
Atenção (disclaimer): Os dados aqui apresentados representam minha opinião pessoal.Não são de forma alguma indicações de compra ou venda de ativos no mercado financeiro.Seleção das partes mais interessantes das Lives de segunda.Live 331 - Visão do Estrategistahttps://youtube.com/live/jLaJNOFK19g
Former Tar Heel QB, and member of the Tar Heel Radio Network, Bryn Renner joins the show, as Bryn talks about the biggest change he's seen for the program under Bill Belichick, he talks about the ongoing QB battle, and how he sees it playing out, and what would qualify as a successful season for the UNC program See omnystudio.com/listener for privacy information.
Nicht jeder Musiker bekommt das, was er verdient. Zum Beispiel Americana-Songwriter James McMurtry, dessen Songs Amerika sezieren wie wenige andere Künstler das können. Musikradio360 mit einem Plädoyer für einen zu Unrecht Unterschätzten.
In this episode of the Epigenetics Podcast, we talked with Erica Korb from the University of Pennsylvania about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. Dr. Korb discusses the focus of her lab, which centers on epigenetic mechanisms impacting gene regulation in neurons. Her research primarily examines histone biology and its connection to neurodevelopmental disorders, including autism spectrum disorder and intellectual disabilities. Dr. Korb expounds on the collaborative environment at UPenn's Epigenetics Institute, emphasizing how the rich diversity of research topics fosters innovative ideas and projects within the community. Reflecting on her earlier work from her postdoctoral studies, Dr. Korb discusses her first significant findings regarding the protein BRD4. This work demonstrated BRD4's role in mediating transcriptional regulation crucial for learning and memory processes. She explains how disrupting this protein's function in neurons hindered critical gene activations required for memory formation in mice. This foundational understanding opened avenues for exploring the broader implications of chromatin regulation in various neurodevelopmental conditions. Transitioning into her current research endeavors, Dr. Korb reveals how she aims to expand her focus beyond Fragile X syndrome. With her lab now investigating multiple chromatin regulators implicated in various forms of autism spectrum disorders, she describes a recent project where RNA sequencing exposed substantial overlaps in gene expression changes associated with five distinct chromatin modifiers, each contributing uniquely to neuronal function while collectively demonstrating sensitivity to chromatin disruptions. A significant portion of the discussion centers around Dr. Korb's unexpected exploration into how COVID-19 intersects with chromatin biology through a phenomenon known as histone mimicry. Leveraging bioinformatic tools during the pandemic, her lab discovered that certain viral proteins mimic histone sequences, which may lead to altered transcriptional outputs in host cells. This coincidental finding illustrates both the creative adaptability needed in scientific research and the importance of collaborative efforts across disciplines to uncover new insights. The conversation also delves into Dr. Korb's recent work regarding the histone variant H2BE, initiated by one of her graduate students. She explains how prior research only recognized H2BE's expression in the olfactory system, yet her lab has demonstrated its significant role in regulating synaptic genes and memory formation throughout broader neuronal contexts. Notably, they identified a single amino acid change that influences H2BE's function in chromatin accessibility and gene transcription, emphasizing its potential evolutionary conservation across species. In terms of H2BE's role, Dr. Korb elucidates that its activity is integral in response to extracellular stimuli, particularly within the context of neuronal activation. Intriguingly, they found that H2BE expression decreases in reaction to long-term neuronal stimulation, suggesting a complex mechanism of homeostatic plasticity crucial for regulating neuronal activity levels. This research not only advances understanding of chromatin dynamics but also holds implications for neuronal health and disease mechanisms. References Feierman, E. R., Louzon, S., Prescott, N. A., Biaco, T., Gao, Q., Qiu, Q., Choi, K., Palozola, K. C., Voss, A. J., Mehta, S. D., Quaye, C. N., Lynch, K. T., Fuccillo, M. V., Wu, H., David, Y., & Korb, E. (2024). Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory. Molecular cell, 84(15), 2822–2837.e11. https://doi.org/10.1016/j.molcel.2024.06.025 Korb, E., Herre, M., Zucker-Scharff, I., Gresack, J., Allis, C. D., & Darnell, R. B. (2017). Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell, 170(6), 1209–1223.e20. https://doi.org/10.1016/j.cell.2017.07.033 Kee, J., Thudium, S., Renner, D. M., Glastad, K., Palozola, K., Zhang, Z., Li, Y., Lan, Y., Cesare, J., Poleshko, A., Kiseleva, A. A., Truitt, R., Cardenas-Diaz, F. L., Zhang, X., Xie, X., Kotton, D. N., Alysandratos, K. D., Epstein, J. A., Shi, P. Y., Yang, W., … Korb, E. (2022). SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry. Nature, 610(7931), 381–388. https://doi.org/10.1038/s41586-022-05282-z Feierman, E. R., Paranjapye, A., Su, S., Qiu, Q., Wu, H., & Korb, E. (2024). Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling. bioRxiv : the preprint server for biology, 2024.11.01.620920. https://doi.org/10.1101/2024.11.01.620920 Related Episodes Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev) DNA Methylation Alterations in Neurodegenerative Diseases (Paula Desplats) The Role of Histone Dopaminylation and Serotinylation in Neuronal Plasticity (Ian Maze) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
This Week on Accunet Ambassadors: Turning "Meh" Homes into "Wow" Homes with Andy Renner from JRL ImprovementsJoin David and Tim as they sit down with Andy Renner of JRL Improvements — the guy who helps homeowners bridge the gap between what their house is and what they want it to be. Whether we're calling him the "Transformation Guru" or the "Outdated Upgrade Leader," one thing's clear: Andy knows how to bring visions to life.From outdated kitchens to uninspired basements, Andy shares insights on how thoughtful design and smart renovation can dramatically boost both comfort and value. If you're thinking about remodeling — or just love a good home makeover story — this episode is for you.
Letzte Woche verstarb Ex-Black-Sabbath-Sänger Ozzy Osbourne nur eine Woche nach dem Abschiedskonzert mit seiner Band. Musikradio360 wirft aus diesem Anlass einen Blick auf seine Solokarriere.
Metallica sind eine der größten Bands der Welt. Dabei haben sie nie den einfachen Weg gewählt und ihre Kritiker attestieren ihnen, sie seien dabei mehrfach falsch abgebogen. Musikradio360 stöbert im Archiv.
Hello, old sports! Join us and our young and beautiful guests, Janet Dale and Allison Renner, as we revisit Baz Luhrmann's The Great Gatsby (2013). Then we chat with Janet and Allison about their new collaborative chapbook, Green Light: A Gatsby Cycle. Read along for our next Bookpisode about Vanishing World by Sayaka Murata on August 5th. Then watch The Thing for our next Othersode with Paul Tremblay, author of the new novel Another, on August 19th.TOC:30 – Hello everyone! Welcome, Janet and Allison! 17:00 – How does this movie hold up?32:00 – Casting44:15 – The music48:45 – Why do people still love Gatsby?57:12– Interview with Janet and Allison!1:38:39 – What's up next?
Zehn Jahre musste Bob Seger schuften, bis ihm endlich der große Durchbruch gelang. Musikradio360 beschäftigt sich heute mit einem Musiker, der immer seinen eigenen Weg gegangen ist.
Josh Peck interviews Rick Renner on his new book, Fallen Angels, Giants, Monsters, and the World Before the Flood.To get the audio-only podcast version of full videos and Josh Peck's blog, which includes original articles, show notes, and more, subscribe to Josh's Substack at http://joshpeck.substack.comDonate: http://PayPal.me/JoshPeckDisclosureCashApp: $JoshScottPeckOr send in your donation to:P.O. Box 270123Oklahoma City, OK 73137Daily Renegade is not 501c3. Your donations are not tax deductible.Don't miss out on Josh Peck's new two-volume book set, The Final Cataclysm: Supernatural Signs of the End Times: https://amzn.to/4hm4YC1Check out Josh Peck's two-volume book set on the history and prophecies of the Dead Sea Scrolls at Prophecy Watchers (make sure to get both volumes because they work together as one big book):Forgotten Prophecies of the Dead Sea Scrolls (Vol.1) - https://prophecywatchers.com/product/... Forgotten Prophecies of the Dead Sea Scrolls (Vol.2) - https://prophecywatchers.com/product/...
Erfolgreicher in Großbritannien als ihn Deutschland, obwohl sie Deutsch sangen: das waren Xmal Deutschland. Die Post Punk-Band feiert derzeit ein kleines Comeback. Musikradio360 geht auf Zeitreise.
Die Hörer von Musikradio360 wollten es wissen: Gibt es eigentlich Anti-Trump-Protestsongs? Die Antwort lautet: Klar doch.
Alison drops new music from RemK, Kaskade, Wooli, Skrillex, Wuki, Levity and many more!Don't forget to rate & review on all of your favorite podcast apps! Post your comments on twitter @awonderland #RADIOWONDERLANDTracklist:RADIO WONDERLAND OPENER 00:00Levity & NITTI - Like This 00:43PinkPantheress - Tonight 02:57Cesqeaux - BANGALORE 05:55Juelz - HACKING THE GATE 09:08AVELLO - Lost in You 11:44Skrillex & Wuki - BIGGY BAP 14:18BLVZE - DANCE (SAY MY NAME) 17:11DJ Carpenter - Cartridge 19:55Underbelly - get2close 23:53Kaskade & Lipless - State Of Mind 26:56RemK - Free Your Mind (feat. Kenzie Gross) 31:54YDG - Let's Go Back 34:27AHEE & Stylust - Oxygen 37:44Mija - WORK THIS (ON MY D) 40:05RemK - Searching For The Words (feat. RENNER) 43:47Subtronics - Mothclaws 45:40Holly - ONME 48:39NGHTMRE - Buried A Friend 50:47neepo - Beacon (feat. CloudNone) 53:38Dimension, Alison Wonderland - Satellite (Wooli Remix) 56:31