Podcasts about arctic university

Eden Shahar is a Jewish-Israeli scholar and educator, currently pursuing her M.A. in Indigenous Studies at UiT- Norway's Arctic University. She brings extensive knowledge of Jewish history, Antisemitism, the Middle East and Intercultural Dialogue. Through her work in Norway, Germany, and Israel, Eden dedicates herself to fostering understanding and positive change through education and meaningful dialogue. Eden also plays a key role at PALSAR. PALSAR unites the Jewish diaspora's fight against Antisemitism, by connecting organizations with thousands of vetted volunteer experts. They offer a secure web platform enables unprecedented intelligence sharing and coordination between communities – transforming Jewish security from reactive to proactive defense. https://palsargroup.org ►  ⁠BLI ⁠⁠⁠⁠MEDLEM⁠⁠⁠⁠⁠  Fremover vil de som er støttemedlemmer få tilgang til episodene først. Da støtter du podcasten med det samme som prisen av en kaffe hver måned. Setter stor pris på om du blir støttemedlem. Tusen takk. ► VIPPS Om du ønsker å støtte arbeidet med denne podcasten, kan du bidra med et stort eller lite beløp, etter eget ønske. All støtte settes pris på, og du bidrar til arbeidet med å lage flere episoder. Bruk Vippsnummer: #823278 ► Du kan altså støtte podden ved å donere et beløp til: ➡ Vipps (lenke for mobil) eller bruk Vippsnummer: #823278 ➡ Eller bli MEDLEM og få tilgang til de nyeste episodene først. ► Omtale/rating: Legg gjerne igjen en omtale/rating på ⁠⁠Spotify⁠⁠ & ⁠⁠Apple Podcasts⁠⁠.  Det hjelper podcasten med å bli synlig for flere. ► Linker: ⁠⁠Youtube⁠⁠ | ⁠⁠Nettside⁠⁠ | ⁠⁠TikTok⁠⁠ | ⁠⁠Instagram⁠⁠ | Podimo | ⁠⁠Facebook⁠⁠ | ⁠⁠Apple

Glaciers have shaped the world's landscapes and continue to affect earth's climate just as human caused climate change impacts them. Datshiane Navanayagam talks to two women dedicating their lives to the study of these giant ice structures. Jemma Wadham is a glacier biogeoechemist and writer whose research has taken her to glaciers in Greenland, Antarctica, Svalbard, Chilean Patagonia, the Peruvian Andes and the Himalaya. She's particularly interested in glacier-hosted life and the impacts of glaciers on the global carbon cycle. She's won several awards for her academic work. Her book Ice Rivers is for a wider audience. She works at the University of Bristol and the Arctic University of Norway.Heidi Sevestre is a French scientist who's studied glaciers around the world, from the French Alps to Greenland, from the Arctic to Antarctica. She's part of the Arctic Monitoring and Assessment Programme and also works on a project looking at the last glaciers of Africa, found in the Rwenzori Mountains National Park, in Uganda. She is passionate about communicating the wonders of the cryosphere and the threats targeting it.Producer: Jane Thurlow(Image: Heidi Sevestre (L) , Credit Mael Sevestre. (R) Jemma Wadham. Credit T Bruckner)

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/south-asian-studies

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo.

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/religion

In this episode, we are joined by the anthropologist Tone Bleie for a discussion of her book A New Testament: Scandinavian Missionaries and Santal Chiefs from Company and British Crown Rule to Independence (Solum Bokvennen, 2023), a pioneering piece of scholarship that innovatively rethinks the economic, legal, and social history of the power-laden relationship between a Scandinavian Transatlantic mission and the Santals, Boro and Bengalis of Eastern India, Northern Bangladesh, and Eastern Nepal. Based on decades of research, the book offers a kaleidoscopic portrait of historical encounters across the longue durée, transporting readers back to the medieval period and Danish and British Company Rule, through to the British Raj and the early post-Independence period. Tone Bleie is Professor of Public Planning and Cultural Understanding at the University of Tromsø, The Arctic University of Norway. Kenneth Bo Nielsen is a social anthropologist based at the University of Oslo. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/christian-studies

The Arctic has become an increasingly active geopolitical battleground for the United States, Russia, and China. Thawing ice caused by climate change opens the possibility of the region becoming a global shipping lane, potentially transforming international trade. China, although not an Arctic nation, has stepped up efforts to expand its presence in the area, creating new opportunities to enforce its interests abroad. The Arctic Council, previously a positive and active body for the region, has not met since Russia's second invasion of Ukraine, reducing international dialogue over the region. Meanwhile, the United States is in the process of increasing its local military deterrent. What are the interests of China, Russia, and the US in the area and how is each working to achieve them? How will climate change affect how nations act towards the Arctic? What will NATO expansion mean for the security of the region?Join us  for a discussion with Evan Bloom, Senior Fellow at the Polar Institute at the Wilson Center, Dr. Marc Lanteigne, Associate Professor of Political Science at the Arctic University of Norway, and Pavel Devyatkin, Senior Associate at the Arctic Institute.Music by Sergii Pavkin and  Mike Cole from PixabayFollow us at:Network2020.orgTwitter: @Network2020LinkedIn: Network 20/20Facebook: @network2020Instagram: @network_2020

In this episode you will meet Jennifer Hays, who is professor in social anthropology at the University of Tromsø (UiT) – the Arctic University of Norway. Jennifer has been working with hunter-gatherer San Populations in southern Africa for 25 years, as a researcher, and as a consultant for governmental bodies and local and international NGOs. She is, among other things, a founding member of the Hunter Gatherer Education Research and Advocacy Group (HG-Edu), a board member of the Kalahari Peoples' Fund. She also works as a consultant for UN bodies on global human rights issues. A primary focus of her work has been on issues relating to education, language, and indigenous rights, including the impact of formal education on San lifeways and on their own efforts to attain educational self-determination.In the podcast, Jennifer gives us insights into what characterises the ways of life of the approximately 10 million people worldwide who live in contemporary hunter-gatherer communities. Focusing on the Ju/'hoansi in the Nyae Nyae conservancy in Namibia, where Jennifer has conducted decades of extensive fieldwork, we discuss some of the challenges that this community face, especially in terms of education and knowledge transmission.Finally, Jennifer offers some reflections on the complex topic of how we can uphold the rights to self-determination of indigenous peoples, and some of the pitfalls that we must take caution to avoid.The episode is part of Regnfang's series of co-publications of the Anthropology on Air podcast. A podcast created and published in collaboration with the Department of Social Anthropology at the University of Bergen. The podcast was recorded in early November 2023 when Jennifer was in Bergen to give a lecture at the Bergen Anthropology Department Seminars.Resources:-       Read more about Jennifer's work and find her publications hereHost and production: Sidsel MarieMusic: Victor Lange

Welcome to a slightly new format for the Edition podcast! Each week will be talking about the magazine – as per usual – but trying to give a little more insight into the process behind putting The Spectator to bed each week.  On the podcast: The Spectator's political editor Katy Balls writes our cover story this week about 'the plot' to oust Rishi Sunak. When former culture secretary Nadine Dorries made the claim in her book that a secret cabal of advisors were responsible for taking down prime ministers, she was laughed at. But with shadowy backroom fixers assembling to try and take down the prime minister, did she have a point? Katy joins the podcast alongside the Financial Times' Stephen Bush to discuss what makes a successful 'plot'. (03:11) Also: Lara and Will take us through some of their favourite pieces from this week's issue, featuring an extract from the 'letter from Antarctica', narrated by its author Robbie Mallet, a polar climate scientist at UiT the Arctic University of Norway. (15:33) Then: The Spectator's commissioning editor Mary Wakefield writes her column this week about XL Bullies. She says that coming face to face with one forced her to change her tune when it comes to the vilified breed and joins the podcast alongside XL Bully owner Sophie Coultard. (19:45) And finally: who knew women love flowers? Henry Jeffreys, for one. Ahead of Valentine's Day he writes this week about his surprise at learning that women do, in fact, love flowers. He speaks with Lara – a former florist herself – about the dos and don'ts of flower purchasing. (32:37) Hosted by William Moore and Lara Prendergast. Produced by Oscar Edmondson. If there are any areas of the magazine that you are particularly interested in or any questions you have for Will and Lara, please email: podcast@spectator.co.uk. We will try and answer as many as we can in next week's episode. 

Welcome to a slightly new format for the Edition podcast! Each week will be talking about the magazine – as per usual – but trying to give a little more insight into the process behind putting The Spectator to bed each week.  On the podcast: The Spectator's political editor Katy Balls writes our cover story this week about 'the plot' to oust Rishi Sunak. When former culture secretary Nadine Dorries made the claim in her book that a secret cabal of advisors were responsible for taking down prime ministers, she was laughed at. But with shadowy backroom fixers assembling to try and take down the prime minister, did she have a point? Katy joins the podcast alongside the Financial Times' Stephen Bush to discuss what makes a successful 'plot'. (03:11) Also: Lara and Will take us through some of their favourite pieces from this week's issue, featuring an extract from the 'letter from Antarctica', narrated by its author Robbie Mallet, a polar climate scientist at UiT the Arctic University of Norway. (15:33) Then: The Spectator's commissioning editor Mary Wakefield writes her column this week about XL Bullies. She says that coming face to face with one forced her to change her tune when it comes to the vilified breed and joins the podcast alongside XL Bully owner Sophie Coultard. (19:45) And finally: who knew women love flowers? Henry Jeffreys, for one. Ahead of Valentine's Day he writes this week about his surprise at learning that women do, in fact, love flowers. He speaks with Lara – a former florist herself – about the dos and don'ts of flower purchasing. (32:37) Hosted by William Moore and Lara Prendergast. Produced by Oscar Edmondson. If there are any areas of the magazine that you are particularly interested in or any questions you have for Will and Lara, please email: podcast@spectator.co.uk. We will try and answer as many as we can in next week's episode. 

Since the Hamas terrorist attacks on October 7th, the level of violence in Gaza and the West Bank has been unrelenting and devestating. Both Hamas and Israel contribute to a cycle of violence and hatred, but to try and understand the conflict further we are joined by Nadim Khoury. He is an Associate Professor at the Department of Law, Philosophy, and International Studies, where he teaches courses in the history of political thought and international relations. Prior to joining the department, he was an assistant professor in political science at Al-Quds Bard College (occupied Palestinian territories, US) and postdoctoral fellow at the department of philosophy at the Arctic University of Norway in Tromsø. He holds a Ph.D. in political theory (University of Virginia, 2012) and an MA in philosophy (University Charles-de-Gaulle, Lille 3). Hosted on Acast. See acast.com/privacy for more information.

Considering himself a nature poet and with a geography degree Simon Armitage pledged to put the environment at the heart of his thinking when he became Poet Laureate in 2019. In this series he travels to the Arctic to see for himself what's going on in this part of the world which is so crucial to the climate change debate. He starts with a visit to a glacier The Steindalsbreen glacier in the Lyngen Alps is over 10 000 years old. His guide is British biochemist Professor Jemma Wadham from UiT, the Arctic University of Norway. After a lifelong obsession with glaciers, Jemma has recently made the north of Norway her home. Her visits to the Arctic, and Svalbard in particular, began when she was studying for her PhD. Her regular study trips mean she has witnessed the changes that are happening here due to climate change and warming for herself. In the Arctic and Antarctic these changes are happening four times faster than the rest of the planet. As well as experiencing the Arctic for himself and seeing first hand what's happening, Simon tries to capture the majesty and vulnerability of the place in new poems written in response to what he finds . Producer - Susan Roberts

Considering himself a nature poet and with a geography degree Simon Armitage pledged to put the environment at the heart of his thinking when he became Poet Laureate in 2019. In this series he travels to the Arctic to see for himself what's going on in this part of the world which is so crucial to the climate change debate. He starts with a visit to a glacier The Steindalsbreen glacier in the Lyngen Alps is over 10 000 years old. His guide is British biochemist Professor Jemma Wadham from UiT, the Arctic University of Norway. After a lifelong obsession with glaciers, Jemma has recently made the north of Norway her home. Her visits to the Arctic, and Svalbard in particular, began when she was studying for her PhD. Her regular study trips mean she has witnessed the changes that are happening here due to climate change and warming for herself. In the Arctic and Antarctic these changes are happening four times faster than the rest of the planet. As well as experiencing the Arctic for himself and seeing first hand what's happening, Simon tries to capture the majesty and vulnerability of the place in new poems written in response to what he finds. Producer - Susan Roberts

In this episode we listen to leading researchers discuss the cryosphere as a link between the Arctic and the Third Pole. The speakers are:Kamrul Hossain, Research Professor, NIEM, Arctic Centre, University of LaplandFu-Kuo Liu, Professor & Director, Centre for Security Studies, National Chengchi UniversityAlbert van Wijngaarden, Visiting Researcher, Arctic Centre, University of LaplandAileen Aseron Espiritu, Researcher & Network leader, The Arctic University of NorwayThis event originally took place at the 2023 Arctic Circle Japan Forum and was organized by: The Northern Institute for Environmental and Minority Law (NIEM), Arctic Centre; in cooperation with UArctic Chair in Arctic Legal Research & Education and UArctic Law Thematic Network. 

In this episode we listen to a discussion on Asian-Nordic collaboration in the Arctic.The speakers are:Aileen Aseron Espiritu, Researcher & Network leader, The Arctic University of NorwayJacob Isbosethsen, Head of Representation in Beijing, Government of GreenlandKristín Ingvarsdóttir, Assistant Professor, University of IcelandMarc Lanteigne, Associate Professor, UiT The Arctic University of NorwayWrenn Yennie Lindgren, Senior Research Fellow, NUPI, The Norwegian Institute of International Affairs; Associate Research Fellow, UI, The Swedish Institute of International AffairsThe discussions are moderated by Juha Saunavaara, Associate Professor, Arctic Research Center, Hokkaido University, Japan.This event originally took place at the 2023 Arctic Circle Japan Forum and was organized by: the University of Iceland 

With Afghanistan once again under Taliban rule and Pakistan reeling under a severe economic and political crisis, the relationship between the neighbouring countries is growing increasingly tense. How can we understand this contentious situation? And, what are the consequences for the civilian population? To discuss these question, and current Afghanistan-Pakistan relations more generally, Kenneth Bo Nielsen is joined by Farhat Taj (University of Tromsø). Farhat Taj is an associate professor at the University of Tromsø, the Arctic University of Norway. Kenneth Bo Nielsen is an Associate Professor at the dept. of Social Anthropology at the University of Oslo and one of the leaders of the Norwegian Network for Asian Studies. The Nordic Asia Podcast is a collaboration sharing expertise on Asia across the Nordic region, brought to you by the Nordic Institute of Asian Studies (NIAS) based at the University of Copenhagen, along with our academic partners: the Centre for East Asian Studies at the University of Turku, and Asianettverket at the University of Oslo. We aim to produce timely, topical and well-edited discussions of new research and developments about Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

With Afghanistan once again under Taliban rule and Pakistan reeling under a severe economic and political crisis, the relationship between the neighbouring countries is growing increasingly tense. How can we understand this contentious situation? And, what are the consequences for the civilian population? To discuss these question, and current Afghanistan-Pakistan relations more generally, Kenneth Bo Nielsen is joined by Farhat Taj (University of Tromsø). Farhat Taj is an associate professor at the University of Tromsø, the Arctic University of Norway. Kenneth Bo Nielsen is an Associate Professor at the dept. of Social Anthropology at the University of Oslo and one of the leaders of the Norwegian Network for Asian Studies. The Nordic Asia Podcast is a collaboration sharing expertise on Asia across the Nordic region, brought to you by the Nordic Institute of Asian Studies (NIAS) based at the University of Copenhagen, along with our academic partners: the Centre for East Asian Studies at the University of Turku, and Asianettverket at the University of Oslo. We aim to produce timely, topical and well-edited discussions of new research and developments about Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/political-science

With Afghanistan once again under Taliban rule and Pakistan reeling under a severe economic and political crisis, the relationship between the neighbouring countries is growing increasingly tense. How can we understand this contentious situation? And, what are the consequences for the civilian population? To discuss these question, and current Afghanistan-Pakistan relations more generally, Kenneth Bo Nielsen is joined by Farhat Taj (University of Tromsø). Farhat Taj is an associate professor at the University of Tromsø, the Arctic University of Norway. Kenneth Bo Nielsen is an Associate Professor at the dept. of Social Anthropology at the University of Oslo and one of the leaders of the Norwegian Network for Asian Studies. The Nordic Asia Podcast is a collaboration sharing expertise on Asia across the Nordic region, brought to you by the Nordic Institute of Asian Studies (NIAS) based at the University of Copenhagen, along with our academic partners: the Centre for East Asian Studies at the University of Turku, and Asianettverket at the University of Oslo. We aim to produce timely, topical and well-edited discussions of new research and developments about Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/middle-eastern-studies

With Afghanistan once again under Taliban rule and Pakistan reeling under a severe economic and political crisis, the relationship between the neighbouring countries is growing increasingly tense. How can we understand this contentious situation? And, what are the consequences for the civilian population? To discuss these question, and current Afghanistan-Pakistan relations more generally, Kenneth Bo Nielsen is joined by Farhat Taj (University of Tromsø). Farhat Taj is an associate professor at the University of Tromsø, the Arctic University of Norway. Kenneth Bo Nielsen is an Associate Professor at the dept. of Social Anthropology at the University of Oslo and one of the leaders of the Norwegian Network for Asian Studies. The Nordic Asia Podcast is a collaboration sharing expertise on Asia across the Nordic region, brought to you by the Nordic Institute of Asian Studies (NIAS) based at the University of Copenhagen, along with our academic partners: the Centre for East Asian Studies at the University of Turku, and Asianettverket at the University of Oslo. We aim to produce timely, topical and well-edited discussions of new research and developments about Asia. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/south-asian-studies

With Afghanistan once again under Taliban rule and Pakistan reeling under a severe economic and political crisis, the relationship between the neighbouring countries is growing increasingly tense. How can we understand this contentious situation? And, what are the consequences for the civilian population? To discuss these question, and current Afghanistan-Pakistan relations more generally, Kenneth Bo Nielsen is joined by Farhat Taj (University of Tromsø). Farhat Taj is an associate professor at the University of Tromsø, the Arctic University of Norway. Kenneth Bo Nielsen is an Associate Professor at the dept. of Social Anthropology at the University of Oslo and one of the leaders of the Norwegian Network for Asian Studies. The Nordic Asia Podcast is a collaboration sharing expertise on Asia across the Nordic region, brought to you by the Nordic Institute of Asian Studies (NIAS) based at the University of Copenhagen, along with our academic partners: the Centre for East Asian Studies at the University of Turku, and Asianettverket at the University of Oslo. We aim to produce timely, topical and well-edited discussions of new research and developments about Asia.

Saturday Mornings host Glenn van Zutphen and award-winning author Neil Humphreys are joined in the studio by Singaporeans Toh Yun Fann, Research Assistant, Earth Observatory of Singapore, and Nanyang Technological University and Yan Yu Ting, Research Fellow, Earth Observatory of Singapore and Nanyang Technological University, who returned in May from the Arctic University of Norway, AKMA3 Expedition to study the organisms and processes related to the natural emissions of greenhouse gases in the Barents Sea in the Arctic region.See omnystudio.com/listener for privacy information.

Ice baths are a popular subject on American social media pages. Kim Kardashian, Harry Styles, Kristen Bell, Lizzo, and other stars have posted about their cold water experiences.冰浴是美国社交媒体页面上的热门话题。 Kim Kardashian、Harry Styles、Kristen Bell、Lizzo 和其他明星都发布了他们的冷水体验。Health claims surrounding ice baths include improved mood, increased energy, weight loss and reduced inflammation. But the science linked to some of those claims is not very strong.围绕冰浴的健康声明包括改善情绪、增加能量、减轻体重和减少炎症。 但与其中一些说法相关的科学依据并不是很强。Here is what medical evidence, experts and fans say about cold water baths, an activity that dates back hundreds of years.以下是医学证据、专家和粉丝对冷水浴的评价，这项活动可以追溯到数百年前。Since June 2020, Dan O'Conor has jumped into Lake Michigan almost daily. The 55-year-old man lives in the city of Chicago.自 2020 年 6 月以来，丹·奥康纳几乎每天都会跳入密歇根湖。 这位 55 岁的男子住在芝加哥市。O'Conor used the term endorphins - “feel good” hormones released in reaction to pain, stress, exercise and other activities – to talk about his experience.奥康纳使用内啡肽这个词——一种对疼痛、压力、运动和其他活动做出反应而释放的“感觉良好”的荷尔蒙——来谈论他的经历。“The endorphin rush … is an incredible way to wake up and just kind of shock the body and get the engine going,” he said on a recent morning when the air temperature was minus-5 Celsius.“内啡肽激增……是一种令人难以置信的唤醒方式，它只是一种刺激身体并让引擎运转的方式，”他在最近的一个早晨说，当时气温为零下 5 摄氏度。With the lake temperature at 1 degree Celsius, O'Conor did a running jump into the icy gray water.湖水温度为 1 摄氏度，奥康纳跑进冰冷的灰色水中。His first jump came early in the pandemic. O'Conor had too much alcohol and his wife was angry at him. She told him to “go jump in the lake.” The common saying is not usually received as a real command.他的第一次跳跃发生在大流行初期。 奥康纳酗酒，他的妻子生他的气。 她告诉他“去湖里跳”。 俗语通常不会作为真正的命令被接受。But, O'Conor acted on it.但是，奥康纳采取了行动。He says the water felt good that June day, so he kept jumping in every day following. As the water grew colder with seasonal change, the good effect was even greater, he said.他说六月的那一天感觉水很好，所以他每天都坚持跳进去。 他说，随着季节变化，水变冷，效果会更好。“My mental health is a lot stronger, a lot brighter. I found some zen down here coming down and jumping into the lake and shocking that body,” O'Conor said.“我的心理健康强多了，也活泼多了。 我发现这里有一些禅宗下来，跳进湖里，震撼了那个身体，”奥康纳说。Dr. Will Cronenwett of Northwestern University's Feinberg medical school tried cold-water immersion once while visiting Scandinavian friends. After a sauna, he jumped into the ice-cold water for a few minutes. He said it was a powerful experience.西北大学范伯格医学院的威尔·克罗南维特博士在拜访斯堪的纳维亚朋友时曾尝试过一次冷水浸泡。 洗完桑拿后，他跳进冰冷的水中泡了几分钟。 他说这是一次很有力量的经历。But Cronenwett says studying cold water immersion with a kind of scientific study known as a randomized controlled trial is difficult. This is because it is hard to develop a placebo for cold water baths.但是 Cronenwett 说，通过一种被称为随机对照试验的科学研究来研究冷水浸泡是很困难的。 这是因为很难开发出用于冷水浴的安慰剂。A placebo is something that has no effect. Placebos are important because scientific tests need to compare the possible effect of something with something else that does not have any physical effect.安慰剂是没有效果的东西。 安慰剂很重要，因为科学测试需要将某物的可能影响与没有任何物理影响的其他东西进行比较。There are a few ideas about how cold water immersion affects the mind.关于冷水浸泡如何影响大脑，有一些想法。Cronenwett says it makes the part of the nervous system that controls the resting state more active. Such an effect may increase feelings of well-being.Cronenwett 说它使控制静息状态的神经系统部分更加活跃。 这种效果可能会增加幸福感。Cold water immersion also affects the part of the nervous system that controls the fight-or-flight stress reaction. Cold water treatment on a usual basis may reduce that reaction. So, Cronenwett said, it might help people feel better able to deal with other stresses in their lives, although that is not proven.冷水浸泡还会影响控制战或逃应激反应的神经系统部分。 通常的冷水处理可能会减少这种反应。 因此，Cronenwett 说，这可能有助于人们更好地应对生活中的其他压力，尽管这尚未得到证实。Czech researchers found that cold water immersion can increase blood levels of dopamine — another hormone — by 250 percent. High amounts have been linked with paranoia and aggression, noted James Mercer of the Arctic University of Norway. Mercer co-wrote a recent scientific paper that examined studies on the treatment.捷克研究人员发现，冷水浸泡可以使血液中多巴胺（另一种激素）的含量增加 250%。 挪威北极大学的詹姆斯·默瑟 (James Mercer) 指出，高剂量与偏执狂和攻击性有关。 Mercer 与人合着了一篇最近的科学论文，审查了有关治疗的研究。Cold water immersion raises blood pressure and increases stress on the heart. Studies have shown this is safe for healthy people and the effects are only temporary.冷水浸泡会升高血压并增加心脏压力。 研究表明，这对健康人是安全的，而且效果只是暂时的。But sometimes these effects can cause the heart to beat unevenly and can cause death, Cronenwett said. People with heart conditions or a family history of early heart disease should talk with a doctor before doing cold water immersion, he said.但有时这些影响会导致心脏跳动不均匀并可能导致死亡，Cronenwett 说。 他说，患有心脏病或有早期心脏病家族史的人在进行冷水浸泡之前应该咨询医生。Repeated cold-water immersions during colder seasons have been shown to improve how the body reacts to insulin, a hormone that controls blood sugar levels, Mercer noted.Mercer 指出，在较冷的季节反复浸泡冷水已被证明可以改善身体对胰岛素的反应，胰岛素是一种控制血糖水平的激素。This might help reduce the risk of getting diabetes. It also might help people with the disease control it. More study is required to know for sure.这可能有助于降低患糖尿病的风险。 它还可以帮助患有这种疾病的人控制它。 需要更多的研究才能确定。Cold water immersion also activates brown fat. This tissue helps keep the body warm and helps it control blood sugar and insulin levels. It also helps the body burn calories.冷水浸泡也会激活棕色脂肪。 这种组织有助于保持身体温暖，并有助于控制血糖和胰岛素水平。 它还可以帮助身体燃烧卡路里。

Ellisiv Mathiesen (The University of Tromsø – the Arctic University of Norway, Tromsø, Norway) discusses the findings of the TWIST trial, which investigated the use of tenecteplase for patients with wake-up stroke who were selected for treatment by non-contrast CT. This Fast-track Article is published in the February issue of The Lancet Neurology.Read the full article:Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST)Continue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

Changes in reindeer sleep regulation across the year: a central role for rumination? In this episode, I am joined by Melanie Furrer, who recently presented her study on sleep in reindeer. Most non-hibernating animals maintain daily “circadian ”rhythms of sleep across the year, as well as “homeostatic” sleep-wake patterns in which increasing time awake is followed by increased sleep amount or intensity. Strikingly, ruminant reindeer in the Arctic show 24-h rhythmicity at the equinoxes but none at either solstice; summertime activity greatly exceeds wintertime activity. So far, nothing is known about their sleep or how it might be seasonally modulated. Methods: We simultaneously recorded non-invasive electroencephalography EEG in four adult female reindeer for four days at The Arctic University of Norway in Tromsø, Norway in July, September, and December. Rapid eye movement, REM sleep, non-REM NREM sleep, and rumination were visually identified from the EEG, and slow-wave activity SWA, EEG power 1–18 4.5 Hz during NREM sleep, the classic marker for homeostatic changes in sleep pressure, was calculated. Results: Although sleep in reindeer generally resembled that of other mammals, key novel adaptations were observed in July/September: n=4, December: n=3. Like most species, sleep-wake distribution paralleled daily activity during seasonally changing light-dark conditions and SWA during NREM sleep increased after prolonged wake periods. Surprisingly, total sleep duration was roughly equal across seasons, and prolonged waking produced a lower SWA response in summer than in winter. As reported for some domestic ruminants, EEG during rumination showed typical characteristics of NREM sleep. Furthermore, rumination appeared to substitute for sleep under all observed conditions. Accordingly, SWA decreased across rumination, and total rumination and NREM sleep durations were negatively correlated. Homeostatic modelling of SWA further suggested that rumination was equivalent to sleep. Conclusions: We suggest that less pronounced SWA increases across waking in summer might indicate higher baseline sleep pressure during this season, possibly resulting from increased activity, food intake and light exposure. Within this context, rumination might partially substitute conventional sleep, permitting near-constant feeding in the arctic summer while compensating for increased sleep pressure. Contact or follow Melanie https://www.kispi.uzh.ch/forschungszentrum/person/furrer-melanie. https://www.researchgate.net/profile/Melanie-Furrer-2   Contact me at iandunican@sleep4performance.com.au or www.sleep4performance.com.au and check out the YouTube channel. Check out our sponsor LMNT. Click on the link to order and get a free LMNT Sample Pack when you order through the custom link below. Key details: • The LMNT Sample Pack includes 1 packet of every flavour. This is the perfect offer for anyone interested in trying all of our flavours or who wants to introduce a friend to LMNT. • This offer is exclusively available through VIP LMNT Partners – you won't find this offer publicly available. • This offer is available for new and returning customers • They offer refunds on all orders with no questions – you don't even have to send it back! DrinkLMNT.com/sleep4performance

[News Focus 3]Conflicts erupting in Central Asia amid the Russia's military retreat우크라전 집중한 사이...화약고 된 러시아 앞마당 Guest: Professor David Alenga, from The Arctic University of Norway Department of Tourism & Northern StudiesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Science diplomacy is a great concept, and one of the things that inspired us to move into this work. Actually Jakob thought about writing a PhD on the topic for a while. But one thing is talking about the concept - another to put it into action in a time of war as we see now with the war in Ukraine. So we invited professor Rasmus Gjedssø Bertelsen from the Arctic University in Norway (UiT) for a chat about why the science community cut all ties to Russia if we are so focused on the possibilities of science diplomacy, why we don't see the potential of science diplomacy in Afghanistan, what to think of the "stick to science campaign" and how research managers can work with science diplomacy in their daily work.Rasmus Gjedssø is work package leader in the H2020 project InsSciDE where he runs a thread on "Power with Science Diplomacy". He is also a working group leader in the EU SD Alliance.Rasmus had a lot on his heart and we had a great conversation about the broad implications of science diplomacy that we can all use in a world that isn't getting easier to navigate.  W also managed to compare universities to characters in Jane Austen novels in our final discussions - and it's always a good episode when we get to talk Jane Austen.  You can learn more about Rasmus and the projects here:On Rasmus; www.arcticgeolab.co You can follow Rasmus on LinkedI: https://www.linkedin.com/in/rasmusgb/You can follow Rasmus on Twitter at: https://twitter.com/RasmusGB Or on Facebook at: https://www.facebook.com/RasmusGBertelsenThe InsSciDE case studies are in open access on www.zenodo.org/communities/insscideYou can read more about the EU Science Diplomacy Alliance at: www.science-diplomacy.euYou can follow the EU Science Diplomacy at Twitter at: @SciDipAllianceOr follow the hashtags: #SciDip and #ScienceDiplomacyThanks for listening. Please share, rate, review and follow us on Twitter @Divrespod .If you're interested in our work with diversity and internationalisation in research, please visit www.diversiunity.com. 

The Smart 7 Ireland Edition is the daily news podcast that gives you everything you need to know in 7 minutes, at 7am, 7 days a week… Consistently appearing in Ireland's Daily News charts, we're a trusted source for people every day. If you're enjoying it, please follow, share or even post a review, it all helps… Today's episode includes references to the following guests: Sherry Rehman - Pakistan Climate Change MinisterAntonio Guterres - UN Secretary GeneralNiaz Ahmed - Head of Policy at WaterAid in PakistanDavid Byers - The Times Assistant Money EditorStephen Smith - Co-founder of StoryFileBill Nelson - NASA AdministratorAlun Hubbard - Professor of Glaciology at the Arctic University of NorwayJonathan Bamber - President of the European Geosciences Union Manel Esteller - Director of the Josep Carreras Leukaemia Research Institute Contact us over at Twitter or visit www.thesmart7.com Presented by Ciara Revins, written by Oliva Davies and Liam Thompson and produced by Daft Doris. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

The Smart 7 is a daily podcast that gives you everything you need to know in 7 minutes, at 7 am, 7 days a week... With over 10 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day. If you're enjoying it, please follow, share, or even post a review, it all helps... Today's episode includes the following guests: Sherry Rehman - Pakistan Climate Change MinisterAntonio Guterres - UN Secretary GeneralNiaz Ahmed - Head of Policy at WaterAid in PakistanDavid Byers - The Times Assistant Money EditorStephen Smith - Co-founder of StoryFileBill Nelson - NASA AdministratorAlun Hubbard - Professor of Glaciology at the Arctic University of NorwayJonathan Bamber - President of the European Geosciences Union Manel Esteller - Director of the Josep Carreras Leukaemia Research Institute In Ireland? Why not try our Ireland Edition? Contact us over at Twitter or visit www.thesmart7.com Presented by Jamie East, written by Olivia Davies and produced by Daft Doris. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

Die Ukrainische Mathematikerin Maryna Viazovska von der ETH Lausanne hat kürzlich die renommierte Fields-Medaille erhalten. Sie ist erst die zweite Preisträgerin in 86 Jahren. Ist Mathematik männlich? Sie hat die Auszeichnung dafür bekommen, dass Sie einen Weg entwickelt hat, wie man Kugeln möglichst dicht packt. Wie kommen Mathematiker*innen eigentlich auf ihre Forschungsideen? Und warum Mathematik schön ist. Professor Klaus-Jürgen Grün und Dr. Irina Kummert im Gespräch mit Cordian Riener, Professor an der The Arctic University of Norway über die Faszination für Mathematik.

The most common type of stroke is one in which a large artery in the brain gets blocked by a blood clot and there are dozens of Cochrane reviews of various treatments for these ischaemic strokes. One of these reviews, looking at the effects of endovascular thrombectomy and intra-arterial interventions, was updated in June 2021 and lead author, Melinda Roaldsen from the Arctic University of Norway in Tromsø, briefly describes the new findings in this  podcast.

The most common type of stroke is one in which a large artery in the brain gets blocked by a blood clot and there are dozens of Cochrane reviews of various treatments for these ischaemic strokes. One of these reviews, looking at the effects of endovascular thrombectomy and intra-arterial interventions, was updated in June 2021 and lead author, Melinda Roaldsen from the Arctic University of Norway in Tromsø, briefly describes the new findings in this  podcast.

In this episode we listen to four distinguished experts discuss the Emerging Arctic Security Concerns that Greenland and Iceland are facing with the growing international attention in the Arctic. The dialogue between Aaja Chemnitz Larsen, Member of the Danish Parliament, Sara Olsvig, Former Vice Premier, Minister in the Government of Greenland and current Member of the Constitutional Commission of Greenland, Marc Lanteigne, Associate Professor, Political Science Department at the Arctic University of Norway and Egill Níelsson, senior Advisor at The Icelandic Center for Research is moderated by Halla Hrund Logadóttir, Director General, National Energy Authority, Iceland. This event originally took place at the 2021 Arctic Circle Assembly in Reykjavík, Iceland and was organized in collaboration with the Centre for Arctic Studies at the University of Iceland.

En el episodio de hoy, de la serie "Lo que hay detrás de un proyecto de investigación" ,contamos el trabajo que hemos desarrollado en conjunto el grupo BIO-HPC de la UCAM junto con Irene Martínez del IMIB y Victor Mulero de la UMU para reposicionar fármacos en el contexto del cáncer colorrectal. La web del grupo de Irene Martínez la podéis encontrar en: http://www.hematoncologia.com/ y aquí su lista de publicaciones: https://www.scopus.com/authid/detail.uri?authorId=14012015600 Por otra parte aquí podéis encontrar las publicaciones de Victor Mulero: https://www.researchgate.net/profile/Victoriano-Mulero y aquí la web del grupo BIO-HPC y publicaciones de Horacio Pérez: https://bio-hpc.eu Si os ha gustado el episodio, podéis continuar la discusión sobre él dentro de nuestra comunidad en discord: https://discord.gg/45UXuqVPvY ¡Gracias! Referencia a las patentes relacionadas: - H. Pérez-Sánchez, I. Martínez-Martínez, J. Peña-García, A. Rodenas-Bleda, J. Peñas-Martínez, D. Zaragoza-Huesca, “Nuevo tratamiento del cáncer colorrectal”. P202130064 (2021). - 12. H. Pérez-Sánchez, I. Martínez-Martínez, J. Peña-García, A. Carmona-Bayonas, M. Rodenas-Bleda, J. Peñas-Martínez, D. Zaragoza-Huesca, V. Mulero-Méndez, I. Pardo-Sánchez, S. Espín-García, “Nuevo tratamiento del cáncer colorrectal”. P202130871 (2021). Agradecimientos: This work was supported by the Instituto de Salud Carlos III (ISCIII), Spanish Ministry of Economy and Competitiveness, Grant Number PI17/00050 & FEDER and the generous donations to Crowdfunding Precipita (FECYT). This work has been funded by grants from Fundación Séneca del Centro de Coordinación de la Investigación de la Región de Murcia [Project 20988/PI/18]; and the Spanish Ministry of Economy and Competitiveness [CTQ2017-87974-R]. Supercomputing resources in this work have been supported by the Poznan Supercomputing Center's infrastructures, the e-infrastructure program of the Research Council of Norway, and the supercomputing center of UiT—the Arctic University of Norway, by the Plataforma Andaluza de Bioinformática of the University of Málaga, by the supercomputing infrastructure of the NLHPC (ECM-02, Powered@NLHPC), and by the Extremadura Research Centre for Advanced Technologies (CETA−CIEMAT), funded by the European Regional Development Fund (ERDF). CETA−CIEMAT belongs to CIEMAT and the Government of Spain. Maria Carmen Ródenas holds a grant from the Spanish Society of Thrombosis and Haemostasis (SETH), David Zaragoza-Huesca holds a predoctoral FPU grant from the Spanish Ministry of Science, and Irene Martínez-Martínez holds a Miguel Servet contract (CPII18/00019) from the Instituto de Salud Carlos III (Madrid). PD: Imagen original tomada de: https://commons.wikimedia.org/wiki/File:7-min.svg Música de fondo "Let the sunshine" tomada de "Keep Calm and Podcast": https://pod.co/keep-calm-and-podcast --- Send in a voice message: https://anchor.fm/horacio-ps/message

To reaffirm the solidity of diplomatic relations between Italy and Norway, the SIOI and the Royal Norwegian Embassy in Italy, in collaboration with the Ministry of Foreign Affairs and International Cooperation, and the High North Center for Business and Governance of the Nord University of Bodø, have decided to organize the third edition of the International Symposium: "Arctic Connections – Sustainable Development in the Arctic: how do we succeed?", that will take place in English and hybrid format on 26 and 27 October 2021. The event will be attended by institutional and academic personalities and international experts to stimulate a reflection on the importance of new energy technologies, business development in the Arctic, bi-multilateral cooperation for the application of the European Green Deal and economic and political factors that could influence the future scenarios of the Arctic Region. Could the Arctic be a pioneer in the energy transition? This is the question that the Arctic States and Observers are called to answer through a debate focused on green energy, international cooperation, and the future of the Arctic Region. To answer this and other questions, we have with us here today Marianne Krey-Jacobsen, Counsellor to the Royal Norwegian Embassy in Rome, Bård Borch Michalsen, Vice-Rector at The Arctic University of Norway, and Trine Jonassen, News Editor of High North News, High North Center for Business and Governance. Speakers: Niccolò Delporto, Giulia Secci Sound engineers: Daniele Baldo, Niccolò Delporto

Charis Gullickson is the Curator and Public Sector PHD Student in Art History at the Arctic University of Norway. Charis has a mantra, and that is: museums are not neutral. They're institutions of culture and agents of change. This is a relatively new concept because, historically, museums have been repositories of antiquities, often displaying artifacts with problematic pasts. This is an issue because without knowing its past, we may revere certain pieces of art and ignore their origins, which could result in perpetuating problematic ideas. So, a lot of Charis' work is focused on contextualizing classic art so that it can be used as a tool for change. Chatter Marks is a podcast of the Anchorage Museum, and is available on Apple Podcasts, Spotify, Amazon Music and Google Podcasts. Just search "Chatter Marks."

Charis Gullickson is the Curator and Public Sector PHD Student in Art History at the Arctic University of Norway. Charis has a mantra, and that is: museums are not neutral. They're institutions of culture and agents of change. This is a relatively new concept because, historically, museums have been repositories of antiquities, often displaying artifacts with problematic pasts. This is an issue because without knowing its past, we may revere certain pieces of art and ignore their origins, which could result in perpetuating problematic ideas. So, a lot of Charis' work is focused on contextualizing classic art so that it can be used as a tool for change.

Join us for the fourth episode of our series and discover the journey of scientist Dr Polona Itkin from a small village in Slovenia to an expedition in the Arctic Ocean aboard the ‘Polarstern' icebreaker ship. She speaks to Jennifer Baker from the Arctic University of Norway in Tromsø about her work on snow and ice models based on data collected during her Arctic travels under the EU-funded project DEARice. Dr Polona Itkin finished her diploma in geography in Ljubljana and then continued her education in Finland, Russia and Germany before obtaining a PhD in Geosciences in 2014. Her passion is sea ice research, in particular how the sea ice is moving, melting and freezing. She has taken part in several research expeditions to the Arctic Ocean and, as part of the DEARice project, was part of the MOSAiC expedition in 2019/2020, where she led the sea ice and snow team on board the research icebreaker ‘Polarstern'. Polona's primary interest is the role of deformed sea ice on the distribution of snow and ice growth and one of the many results of DEARice and MOSAiC will be a better representation of such processes in climate models.Find out more:Link to project on CORDIS Link to EU-funded project website: DEARiceFor more EU-funded research and innovation success stories Hosted on Acast. See acast.com/privacy for more information.

A leading international agency has upgraded its forecast for global growth for this year. The Organisation for Economic Cooperation and Development said the world economy is likely to expand by 5.6% in 2021, and its chief economist Laurence Boone explains why the OECD believes prospects for growth are looking rosier. Also in the programme, the China National Offshore Oil Company, or CNOOC, has been de-listed from the New York Stock Exchange, and the BBC's Samira Hussain tells us what's behind the move. Plus, we take an in-depth look at Greenland, whose economy some believe is ripe for expansion. Allun Hubbard, a professor of glaciology at the Arctic University of Norway discusses prospects for agriculture in Greenland. The country depends heavily on funds from Denmark, but former Greenland prime minister Aleqa Hammond explores whether it could ever become independent. And Tracy Marchaud of the University of Southern Maine makes the case for a stronger tourism sector on the island. (Picture: Construction workers. Picture credit: Reuters.)

Arctic security and international relations expert Marc Lanteigne explores China's scientific, economic, and political interests in a rapidly changing region. Dr. Marc Lanteigne is an associate professor of political science at UiT - the Arctic University of Norway, and is the author and editor of several books, including Routledge Handbook of Arctic Security (Routledge 2020).

In this episode, I interview Cassandra Falke, professor of English Literature ad UiT, The Arctic University of Norway, about her book The Phenomenology of Love and Reading (Bloomsbury Publishing, 2016). In the text, Falke situates herself within the current revival of the interest in ethics in literary criticism, which coincides with a rise in neuroscientific discoveries about cognition and emotion that similarly have been incorporated into literary studies. Aware of these recent developments, Falke argues that literary study must ground itself philosophically—rather than just scientifically—in order to speak convincingly about literature’s relationship(s) to our ethical lives. To do this, The Phenomenology of Love and Reading recasts French philosopher Jean-Luc Marion’s articulations of a phenomenology of love onto the event of reading. The Phenomenology of Love and Reading accepts Jean-Luc Marion's argument that love matters for who we are more than anything—more than cognition and more than being itself. Falke shows through deft readings of both philosophical and literary texts, as well as ruminations on the experience of reading, how the act of reading can strengthen our capacity to love by giving us practice in love´s habits—attention, empathy, and a willingness to be overwhelmed. Confounding our expectations, literature equips us for the confounding events of love, which, Falke suggests, are not rare and fleeting, but rather constitute the most meaningful and durable part of our everyday life. Britt Edelen is a Ph.D. student in English at Duke University. He focuses on modernism and the relationship(s) between language, philosophy, and literature. You can find him on Twitter or send him an email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

In this episode, I interview Cassandra Falke, professor of English Literature ad UiT, The Arctic University of Norway, about her book The Phenomenology of Love and Reading (Bloomsbury Publishing, 2016). In the text, Falke situates herself within the current revival of the interest in ethics in literary criticism, which coincides with a rise in neuroscientific discoveries about cognition and emotion that similarly have been incorporated into literary studies. Aware of these recent developments, Falke argues that literary study must ground itself philosophically—rather than just scientifically—in order to speak convincingly about literature’s relationship(s) to our ethical lives. To do this, The Phenomenology of Love and Reading recasts French philosopher Jean-Luc Marion’s articulations of a phenomenology of love onto the event of reading. The Phenomenology of Love and Reading accepts Jean-Luc Marion's argument that love matters for who we are more than anything—more than cognition and more than being itself. Falke shows through deft readings of both philosophical and literary texts, as well as ruminations on the experience of reading, how the act of reading can strengthen our capacity to love by giving us practice in love´s habits—attention, empathy, and a willingness to be overwhelmed. Confounding our expectations, literature equips us for the confounding events of love, which, Falke suggests, are not rare and fleeting, but rather constitute the most meaningful and durable part of our everyday life. Britt Edelen is a Ph.D. student in English at Duke University. He focuses on modernism and the relationship(s) between language, philosophy, and literature. You can find him on Twitter or send him an email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

In this episode, I interview Cassandra Falke, professor of English Literature ad UiT, The Arctic University of Norway, about her book The Phenomenology of Love and Reading (Bloomsbury Publishing, 2016). In the text, Falke situates herself within the current revival of the interest in ethics in literary criticism, which coincides with a rise in neuroscientific discoveries about cognition and emotion that similarly have been incorporated into literary studies. Aware of these recent developments, Falke argues that literary study must ground itself philosophically—rather than just scientifically—in order to speak convincingly about literature’s relationship(s) to our ethical lives. To do this, The Phenomenology of Love and Reading recasts French philosopher Jean-Luc Marion’s articulations of a phenomenology of love onto the event of reading. The Phenomenology of Love and Reading accepts Jean-Luc Marion's argument that love matters for who we are more than anything—more than cognition and more than being itself. Falke shows through deft readings of both philosophical and literary texts, as well as ruminations on the experience of reading, how the act of reading can strengthen our capacity to love by giving us practice in love´s habits—attention, empathy, and a willingness to be overwhelmed. Confounding our expectations, literature equips us for the confounding events of love, which, Falke suggests, are not rare and fleeting, but rather constitute the most meaningful and durable part of our everyday life. Britt Edelen is a Ph.D. student in English at Duke University. He focuses on modernism and the relationship(s) between language, philosophy, and literature. You can find him on Twitter or send him an email. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm

In today's episode, Sarah and Danielle interview Brandon Nagy and Else Høeg Sundfør regarding their experiences as engineers in the Oil and Gas industry. Brandon is a Chemical Engineer who graduated from the University of Toronto in 2018. He is currently working as a Drilling and Measurements (D&M) Field Engineer for Schlumberger in Qatar. Else did a Bachelor of Science in Process and Gas Engineering at the Arctic University of Norway. In 2017, she graduated from the Norwegian University of Science and Technology with a Masters of Science in Mechanical Engineering with a specialty in Fluid Dynamics and Renewables. Through their unique perspectives, they discuss gender differences in STEMM by comparing and contrasting their journeys in the field of engineering.

Have you ever been caught in an avalanche or spoken to someone who survived? In this episode, you’ll hear what living through an avalanche is really like. Audun Hetland (a psychologist) and Andrea Mannberg (an economist) are researchers at the White Heat Project in Tromsø, Norway. The project is a collaboration between The Arctic University of Norway, Montana State University, and Umeå University, in Sweden. Their international team also includes researchers in geography, snow science, and political science. They are focused on the effects of positional preferences and bounded rationality on risk-taking behavior, and more specifically, skiing in avalanche terrain. As project leader, Andrea spoke about how this interdisciplinary team is helping backcountry skiers do a better job of managing their risk in avalanche terrain. To do so, they are studying decision-making under uncertainty and the curious way cold and hot states affect our choices. Their work has clear implications for corporate leaders who make decisions about budgets and human resources, and in many situations, the consequences can be quite high. In case you’re not familiar with Tromsø, Norway, it is a 2-hour flight north of the Arctic Circle. © 2020 Behavioral Grooves   Links Andrea Mannberg, PhD and Audun Hetland, PhD: https://uit.no/research/care White Heat Project: https://whiteheatproject.com/ Bridger Bowl: https://bridgerbowl.com/ George Loewenstein & Dan Ariely’s paper on hot states vs. cold states: https://onlinelibrary.wiley.com/doi/abs/10.1002/bdm.501 Seinfeld Morning Guy vs. Night Guy: https://www.youtube.com/watch?v=UEe2pN8oksc Max Bazerman “Better, Not Perfect” Episode 196: https://behavioralgrooves.com/episode/living-happier-by-making-the-world-better-with-max-bazerman/ Common Biases & Heuristics: https://docs.google.com/document/d/1XHpBr0VFcaT8wIUpr-9zMIb79dFMgOVFRxIZRybiftI/edit?usp=sharing   Musical Links John Coltrane “Green Dolphin Street”: https://www.youtube.com/watch?v=ePScRElDHOY Tom Waits “Tom Traubert’s Blues”: https://www.youtube.com/watch?v=hvFyt2kmrZk White Stripes “Seven Nation Army”: https://www.youtube.com/watch?v=DKdmdCtPtnQ Monster: https://en.wikipedia.org/wiki/Monster_(band) Monster: https://open.spotify.com/artist/0c9qOU7URKA43mMlgJApmV?si=we-OrwjYS4GVksnTwNOt4g The Clash “London Calling”: https://www.youtube.com/watch?v=BlLbrID7oDg Folk og Røvere: https://open.spotify.com/artist/5jVLZ3NoJJ5kRcSnYOgSHO Philter: http://open.spotify.com/album/1sbcw2kjPf5ZcLU5n7oGSt Andrea’s “dance song”: https://www.youtube.com/watch?v=C9GqMuW9_Z8 Isolation Years (A band from Andrea’s home town): https://open.spotify.com/album/4nNOnikF2OVzBF9BqNxkHb?si=7Tkv4JujTPy99WytOG1H8A The Knife: https://open.spotify.com/album/7lbXNgtug37CDpS7N7NkrL?si=AAwopJtDRQKpUe-EOJAYCw First Aid Kit: https://open.spotify.com/artist/21egYD1eInY6bGFcniCRT1?si=ASWNJUigSPKAjgUkG66DcQ  

In this episode, we are discussing how to teach open science to PhD students. Helene N. Andreassen, head of Library Teaching and Learning Support at the University Library of UiT the Arctic University of Norway shares her experiences with the integration of open science in a special, tailor-made course for PhD's that have just started their project. An interdisciplinary, discussion-based course, "Take Control of Your PhD Journey: From (P)reflection to Publishing" consists of a series of seminars on research data management, open access publishing and other subject matters pertaining to open science.

Last year, China published its Arctic Policy white paper, positioning itself as a stakeholder in Arctic governance and making waves internationally as countries tried to understand China’s intentions. Why is China so interested in the Arctic region? And how do the impact of warmer temperatures and climate change shift China’s priorities in the North Pole? From Belt and Road initiatives to bans on fishing, China performs a delicate balancing act working with the sovereign nations of the Arctic. Guests:Dr Zhao Huiyu, Shanghai Jiao Tong UniversityDr Marc Lanteigne, Arctic University of NorwayDr Anne-Marie Brady, University of CanterburyDr Liu Nengye, University of AdelaideDr Henry Huntington, Ocean Conservancy Dr Shi Yubing, Xiamen UniversityDr Mia Bennett, University of Hong KongDr Peter Winsor, World Wide Fund Marc-Andre Dubois, Canadian Parks and Wilderness SocietyDr Timo Koivurova, University of Lapland Credits:Sound Engineer: Chris WoodINTRO/OUTRO Music: Alex Mauboussin

Why is it important to preregister research studies? How do you do it, and what kind of bad science do you avoid when you do this within an open science framework? All these questions are answered by our guest, associate professor Matthias Mittner at the research group for cognitive neurosciences at UiT the Arctic University of Norway. The host of this episode is Erik Lieungh.

Jane Ferguson:  Hello, everyone. Welcome to Episode 23 of Getting Personal, Omics of the Heart, the podcast from Circulation: Genomic and Precision Medicine. It's December 2018. I'm Jane Ferguson. So let's get started.                              This month I talked to Dr. Merlin Butler from Kansas University Medical Center about an interesting clinical case he described recently in the Journal of Pediatric Genetics, concerning cardiac presentations in a case of classic Ehlers-Danlos syndrome with COL5A1 mutations.                              Keep listening for that interview, but first, let's talk about the papers in this month's issue of the Journal.                              Our first paper, entitled "Effects of Genetic Variance Associated With Familial Hypercholesterolemia on LDL Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program." Comes from Yan Sun, Peter Wilson and co-authors on behalf of the V.A. Million Veterans Program. They were interested in the relatively between variants in LDLR, APOB and PCSK9, and LDL cholesterol in the general population. Low-frequency variants in these genes have been identified to underlie the greatly elevated LDL cholesterol seen in cases of familial hypercholesterolemia, but the effects of the population level are unknown.                              Using data from the Million Veterans Program, the team analyzed the associations between putatively pathogenic variants and the maximum recorded LDL cholesterol level, as measured repeatedly over a 15-year period, in over 330,000 participants. They restricted analysis to variants that were present in at least 30 people and found that eight of the 16 variants tested were associated with significantly higher LDL cholesterol. Through phenome-wide association analysis, they found that carriers had a higher likelihood of a diagnosis of hypercholesterolemia or coronary heart disease, but not of other diagnoses. Even though individuals carrying risk variants generally reduce their LDL cholesterol through statin treatment, they still had residual risk, suggesting that even earlier initiation of treatment may be required in individuals with genetic risk of high HDL.                              Continuing the theme, the next paper comes from Laurens Reeskamp, Merel Hartgers, Kees Hovingh and colleagues from the University of Amsterdam, and is entitled, "A Deep Intronic Variant in LDLR in Familial Hypercholesterolemia: Time to Widen the Scope?" This team had encountered a family with familial hypercholesterolemia, who did not carry a coding mutation in LDLR, APOB or PCSK9, and they wanted to figure out what was causing the elevated LDL cholesterol in this family. They conducted whole-genome sequencing in nine family members, five affected and four unaffected. They found a variant in an intron in LDLR, which resulted in an insertion of 97 nucleotides, leading to a frame shift in premature stop codon in exon 15 of LDLR. They confirmed the disease segregation in a second family, and found a frequency of over 0.2% in additional FH cases without a confirmed mutation.  This study highlights the need to consider more than just exons when looking for causal variants, particularly in families where no coding mutations are identified.                              Next up, from Kathryn Siewert and Ben Voight from University of Pennsylvania, a paper reporting that "Bivariate Genome-Wide Association Scan Identified 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease." This paper started with a premise that, because heritable plasma lipids are genetically linked to coronary artery disease, we would have greater power to detect variants contributing to both traits by conducting joint GWAS analysis, rather than independent analyses for lipids or coronary disease, as has been done traditionally. Using data from over 500,000 individuals for CAD and over 180,000 individuals from the Global Lipid Genetics Consortium, they conducted a bivariate GWAS and identified six previously unreported loci that associated with CAD and either triglycerides, LDL cholesterol or total cholesterol. Many of these loci also had signals for effects on gene expression of genes in the region, suggesting that these novel loci may affect lipid levels and CAD risk through modulation of gene expression. Interestingly, for some of the newly-identified loci, there were multiple potential regulatory targets, suggesting that these loci may affect lipids and CAD through separate mechanisms. Overall, for closely-linked traits such as lipids and CAD, this joint GWAS approach gives additional power to detect novel variants.                              The next article comes from Terry Solomon, John-Bjarne Hansen and colleagues from University of California-San Diego and the Arctic University of Norway. Their paper concerns the "Identification of Common and Rare Genetic Variation Associated With Plasma Protein Levels Using Whole-Exome Sequencing and Mass Spectrometry." They were interested in identifying genetic variants that associate with plasma protein levels, both to understand genetic regulation and to identify potential sources of bias, where a genetic variant affects the assay used to quantify the protein, without necessarily altering biological components of the protein. Using data from 165 participants of the Tromsø Study, they quantified 664 proteins in plasma by tandem mass tag mass spectrometry and genotypes by whole-exome sequencing. They identified 109 proteins or peptides associated with genotype, and of these identified 49 that appeared to be technical artifacts based on genotype data.  Of the rest, many of the genetic variants affected protein level by modulation of RNA, but some appeared to directly affect protein metabolism. Their method of quantifying multiple peptides from each protein and sequencing exons allowed them to identify spurious associations that would often be missed, and highlights the large number of artifacts that could be present in protein quantitative trait locus studies. At the same time, they show that over half of the pQTLs are real, with genetic variants affecting circulating proteins through diverse mechanisms.                              Our last of the full-length original research articles also applied proteomics. "Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy" comes from Caroline Coats, Perry Elliott and coauthors from University College, London. They obtained myocardial samples from 11 patients with hypertrophic cardiomyopathy and measured over 1500 proteins using label-free proteomic analysis. They compared protein expression to six control samples from healthy hearts. They identified 151 proteins that were differentially expressed in HCM hearts, compared with control, and they validated a subset of these using an additional 65 myocardial samples from healthy and diseased subjects. Of eight validated differentially expressed proteins, they represented pathways in metabolism, muscle contraction, calcium regulation and oxidative stress. Of particular interest, they highlighted lumican as a novel disease protein, and showed the potential of proteomics to identify mechanisms underlying HCM.                              We have two research letters this month, the first from Hisato Suzuki, Kenjiro Kosaki and coauthors from Keio University School of Medicine at Tokyo. It's titled, "Genomic Comparison With Supercentenarians Identifies RNF213 as a Risk Gene for Pulmonary Arterial Hypertension." In this letter, they were interested in identifying genetic variants underlying pulmonary arterial hypertension. They hypothesized that individuals with extremely long lifespan would be less likely to carry potentially pathogenic variants. They performed whole-exome sequencing in 76 individuals with PAH and compared them to 79 supercentenarians who had lived for over 110 years. They report variants in RNF213 and TMEM8A that were present in PAH but not in the controls, suggesting these genes may be important in the pathophysiology of PAH.                              The second research letter comes from Tessa Barrett, Jeffrey Berger and colleagues from New York University School of Medicine, and is entitled, "Whole-Blood Transcriptome Profiling Identifies Women With Myocardial Infarction With Nonobstructive Coronary Artery Disease: Findings From the American Heart Association Go Red for Women Strategically Focused Research Network." Most of the 750,000 acute MIs occurring in the U.S. each year are caused by obstructive coronary artery disease, but around 15% of the acute MIs occur in individuals whose arteries have less than 50% stenosis and are defined as unobstructed. These individuals are more likely to be female and of higher morbidity and mortality. In this AHSAFRM-funded project, the team sequenced whole-blood RNA from 32 women who presented with an MI with or without CAD, or controls. They report several thousand transcripts differing between groups on conducted pathway analysis, which highlighted several pathways, most notably estrogen signaling. This suggests that estrogen may be a novel component in MIs occurring in the absence of obstructive disease.                              We also have two clinical letters this month. The first, "Desmoplakin Variant-Associated Arrhythmogenic Cardiomyopathy Presenting as Acute Myocarditis," is brought to us by Kaitlyn Reichl, Chetan Shenoy and colleagues from University of Minnesota Medical School. They report a case of a 24-year-old man presenting with acute myocarditis, who was found to have a pathogenic variant in desmoplakin underlying arrhythmogenic cardiomyopathy, also present in his father and one brother. This case highlights myocarditis as a possible initial presentation of arrhythmogenic cardiomyopathy, which requires cardiac MRI and genetic testing for full evaluation.                              The second clinical letter comes from Judith Verhagen, Marja Wessels and co-authors from University Medical Center, Rotterdam, and is entitled, "Homozygous Truncating Variant in PKP2 Causes Hypoplastic Left Heart Syndrome." They report on a family with consanguineous parents, where two children were affected with left ventricular hypoplasia, leading to intrauterine death in one child and death at day 19 of life in a second child. Sequencing identified a variant in PKP2, which encodes plakophilin 2. Both parents were heterozygous for the mutation, and their affected children were homozygous for the mutation. This mutation resulted in disorganization of the sarcomere and affected localization of other proteins affecting gap junctions. The case highlights PKP2 variants as causal in hypoplastic left heart syndrome.                              Dr. Merlin Butler is a professor at Kansas University Medical Center and Director of their Division of Research and Genetics. Dr. Butler joined me to discuss an interesting case of Ehlers-Danlos Syndrome in a father and son, with heart failure in the father. This case is in press in the Journal of Pediatric Genetics, and the prepublication version is available online, published on the 13th of October 2018. We'll tweet out a link to that paper, if you're interested in viewing the full case, but here's Dr. Butler, who joined me to discuss it now. Dr. Butler:          ... I'm a clinical geneticist here at University of Kansas Medical Center, and I see both adult and pediatric patients, but one of the more common reasons for referral to my adult side clinical genetic services is connective tissue disorders. And that's how we were involved with this particular family, a son and father, that led to my interest in looking at the question about genetics of cardiac transplantation of those patients that present for cardiology services because of heart failure and worked up and ultimately end up as a candidate for transplantation.                              And that transpired in this particular family, which the patient was a 13-year-old boy who was referred into the clinic because of connective tissue disorder. Actually the primary care wanted to rule out Ehlers-Danlos Syndrome. And so we evaluated the 13-year-old boy in the clinic setting, and then we ordered comprehensive connective tissue and next-generation DNA sequencing panel, and lo and behold, he had a mutation of the classical gene that causes classic Ehlers-Danlos, the collagen 5A1 gene. The gene variant was classified as unknown clinical significance, which is often the case as we know with this technology, next-generation sequencing. Regardless of the condition we're looking at, we find about 10% of time, the panel of tests, the panel of genes that come back that are tested. 10% of the time we find no variants, no spelling errors, no mutations. 10% of the time the results come back from the commercial laboratory ... these are clinic patients, so it's done in commercially-approved laboratories, clinically-approved laboratories ... and we find that about 10% is pathogenic, which means it's disease-causing. The gene variant or mutation has been reported before. There is information in the literature that we know that it causes disease, Ehlers-Danlos, whatever type.                              About 80% of the time, the results come back as unknown clinical significance, and this is related to connective tissue. You probably order a test in cardiology or any other service and you'll find the same area. Most of the variants come back as unknown. What is meant by that is they haven't been reported previously in the literature, and therefore we don't know ... They may be disease-causing, that particular change, but we don't know that. We as geneticists, we have to then figure out whether that gene variant is a mutation or background noise. So we go through a process by where we try to characterize that particular gene finding to see whether it could be causative in that particular patient we see, or if it looks like it's probably tolerated and is just background noise, and it has really probably no apparent phenotypic change resulting from that particular gene variant.                              So this particular gene variant that we found, the collagen 5A1, did meet the criteria. We looked for computer programs and silica prediction to see if it was tolerated or damaging. We looked at how common that gene variant is seen in the general population, looking at exact various types of genome databases at the laboratories used to search for that variant in the population that's been serviced by genetic services, to see how rare it is or how common it is. We also check to see if it's a missense change, missense variant that is, one amino acid got switched for a different amino acid. There are five classes of amino acids, so if they stay within the same class, that change one amino acid to the next probably doesn't have much meaning, but if it changes to an entirely different class, like positive to negative, hydrophilic to hydrophobic, that could make a big change at the protein translation level, and therefore impact on protein development and function.                              And then we looked to see if it's conserved in evolution. The laboratories that we use, they look at approximately 80 different animals, mammals, vertebrates, primates, non-mammal vertebrates, to see if that particular spelling change is conserved throughout evolution. If it is, if C is always that position 205 in the coding sequence of that gene throughout evolution, that means you need to have C at that position, not A, G or T, because that would be conserved and impact that we don't want to change that, because it's conserved through evolution.                              So those kind of criteria, how common it is in the population, how conserved it is, what the amino acid change might be and what the computer programs predict that change might relate to the function of the protein. So we used those criteria, found this gene variant, although it hadn't been reported before ... well, it hasn't been characterized as pathogenic. In this particular family, 13-year-old son and 55-year-old father, they both had the classical features of classic Ehlers-Danlos, so that gene variant, we know at this point is informative. Dr. Ferguson:    That's a really helpful introduction to how you go about looking at variants and screening them and picking the ones of most importance. So you had this 13-year-old patient who came in and then you tested the patient, and then did you also test both parents? Other family members? Dr. Butler:          Well, the mother was no longer in the loop, so the primary care, the pediatrician, referred this 13-year-old boy because of joint laxity. He had experienced multiple spontaneous knee dislocations, beginning around nine years of age. He was 13 when I saw him in clinic. He had a history of knee pain, generalized joint hypermobility, loose skin, excessive bruising and poor scarring. And he had that history coming in, and we certainly could identify those findings on this patient. In fact, we reported this patient in the literature. The title of the paper is "Classic Ehlers-Danlos Syndrome in a Son and Father with a Heart Transplant Performed in the Father," published in Journal of Pediatric Genetics, but during a genetics clinic visit, we assessed a hypermobility Beighton scale, that we used to determine the degree of hypermobility, hyperflexibility, and we recorded a score of eight out of nine. Nine is the maximum number. And what we use as kind of a cut-off, this score is five or more, five out of nine or more, then that would indicate that probably there is some kind of joint issues, connective tissue disorder in the way.                              He had no heart murmur detected, normal rate and rhythm, but a previous echocardiogram showing he had no valvular problems but he had aortic root dilation. He also had skin marbling, atrophic scars, particularly on the lower leg, and increased pigment secondary to easy bruising. He had asymmetry of the anterior body wall, pretty classical findings that we recognize in Ehlers-Danlos. Dr. Ferguson:    So the reason we're talking to you about this is actually less related to the son, right? And then related to what you found in the father. Dr. Butler:          The father, right. So the father was 55 years old when we saw him. So we did testing on the son, based on his examinations, and then we obtained DNA and we found out, had the sequencing. We found he had a gene variant of the collagen 5A1 gene. And the collagen 5A1 codes for collagen, low fibrils protein changes, and that's a classical finding we see in Ehlers-Danlos. So we then, on follow-up, we looked more closely at the father, based on what we found in the child, and the father is 55 years of age and he exhibited similar clinical features seen in his son, including stretchable, thin skin, poor scarring, hypermobile joints, with pain and easy bruising. He had a Beighton score of six out of nine, but due to multiple knee surgeries, we were really not able to able to assess his knee findings.                              And he had strabismus repair when he was like 12 years of age. He had surgery on his right knee due to frequent dislocations, and had bilateral foot surgeries due to flat feet, pes planus. He had a stroke at 37 years of age, but without hypertension. At 43 years of age he underwent a heart transplant because of heart failure with no known cause, such as infections or anatomical defects or metabolic problems seen. And at 54 years of age he had fusion of the lower vertebrae, correct complications, nerve compression, impacting ambulation. So he had multiple, multiple problems, and we did DNA testing on him. He also had the same gene variant of the collagen 5A1 gene, which causes classic Ehlers-Danlos Syndrome. Dr. Ferguson:    Yeah, so he essentially had been undiagnosed his entire life, I guess. Dr. Butler:          In his entire life, he just kind of lived with it. Obviously no one really picked it up because he had multiple, multiple orthopedic surgeries. Of course he had the cardiac transplant because of a very large heart size. They didn't really find out what had taken place with that. They didn't find any reason why he had heart failure. So, because of this connective tissue issue, I began to think more closely about this. Could somehow his cardiac transplantation due to no determined reason why he had heart failure, could that somehow be related to a connective tissue problem, such as classic Ehlers-Danlos?                              And classic Ehlers-Danlos is fairly common, about one in 20,000 people. As far as our concern in the field of genetics, one in 20,000 is common, because we see rare diseases. So one in 20,000 is common. There's like six different categories of Ehlers-Danlos in classic and hypermobile form, vascular form, but he had the clinical findings, he and his son, and he had mutation of a gene that causes classic Ehlers-Danlos.                              So the thrust of this communication is, could it be that there may be a group of individuals that are on a heart transplantation service, waiting to be transplanted, that might have a connective tissue disorder, such as Ehlers-Danlos or one of the other connective tissue disorders, that could be an issue and a causation of their cardiac issues? We know that there are around 70 genes being recognized that cause connective tissue, and these numbers increase all the time as we learn more about genetics and the capabilities of testing. There are over 130 recognized genes that are thought to play a role in hereditary cardiomyopathies and there are now thought to be over 230 genes that are commercially available in a comprehensive cardiovascular next-generation DNA panels, and several of those genes are collagen genes.                              So we know there are hundreds of genes that play a role with cardiac health, I guess. Disturbance of those genes, several of those could be connective tissue. Obviously there's others involved, too ... myopathies and conduction issues. But the question I would have, the focus is, could there be a group that would have a connective tissue? And why is that important? Well, not only do they have issues when it comes to these multiple surgical concerns, but they may have, obviously, concerns that might be related to complications of surgery. We know that connective tissue disorders, they have poor wound healing, scarring and other tissue involvement such as vascular anomalies, aneurysms. So they become ... whether it's for cardiac procedures or whether it's orthopedic, whatever ... they become poor candidates for surgical intervention, for surgical operation procedures, because of the complications of surgery. Connective tissue, poor wound healing, scarring.                              And because connective tissue is involved in not only the skin, but involves internal organs such as the vessels, where you're concerned about aneurysms and vascular anomalies, that could be playing a role. So there may be more complications related to the surgical procedures than your typical patient who undergoes heart transplantation.                              So I think that would be important to know, so I would encourage, for the cardiology services, for patients that are on these transplant care and services, to consider a comprehensive genetic DNA analysis to look at connective tissues, as well as other causations of cardiac disease. As I mentioned, there's over 200 different genes been recognized now on comprehensive DNA testing panels related to cardiac and connective tissue problems.                              So, I would encourage that patients that are on the transplant list, they should undergo a next-generation detailed comprehensive connective and cardiovascular panel ... they're certainly available in several laboratory settings ... that might help lead to not only the diagnosis of the cardiac issues, but might help in medical management and monitoring and the surveillance, as well as the surgical interventions and care following the surgical procedures might be taking place.                              Frequently have an arterial wall might be a little fragile and obviously clamping during surgical procedures for an extended period of time might cause some trauma, even to a normal artery, let alone an artery that might be disorganized because of connective tissue problem. Dr. Ferguson:    Yeah. Dr. Butler:          So those complications might occur as well, too, during the procedure or following the procedure. Even there may not be any aneurysms going in, there might be a weakness of the arterial wall at the clamp site that could lead to an aneurysm following the procedure, so it needs to be monitored.                              So I'm just bringing these to the medical attention that may or may not be out there, but I want to bring this to ... You know, there have been over 90,000 heart transplants been done since 1983, at least that many, and there's 23 million people worldwide that are affected with congestive heart failure, and that's about 7.5 million people in North America. Dr. Ferguson:    Yeah. Dr. Butler:          So it's out there. Some of these genetic conditions are rare, but collectively they're common. Ehlers-Danlos, one in 20,000, is probably considered rare, but yet it still is not rare to the person that has it. Dr. Ferguson:    Right, right, and maybe enriched in these patient populations. So is this something you think that could be sort of found with more careful physical exams, or do you think that [crosstalk] genomic sequencing is sort of the best way to get at this? Dr. Butler:          Well, I think that Beighton scale we just mentioned, the hypermobility scale, just to see if there's, you know, if it's pretty common. Most adults can't put their palms on the floor when they're standing up. Dr. Ferguson:    I certainly can't. Dr. Butler:          That is usually not gonna happen for multiple reasons. But maybe some of the cardiologists are, but those that aren't, maybe they should consider, just check for hyperflexibility in their adult patient. [crosstalk] Dr. Ferguson:    Yeah, that seems like an easy [crosstalk] click-and-check, right? Dr. Butler:          Right. There being loose skins, poor scarring. You can ask the patient, obviously. Easy bruisability and poor scars, and it's pretty obvious in these conditions. I mean, on a physical exam it jumps out at you, particularly the multiple scars and bruising on the lower extremities with the pigmented because of iron deposits. You'll see that pretty clear in the scarring issues.                              And they'll tell you, too. I mean, the patients, they know. "Oh, yeah. I'm very hyperflexible." So you just ask the question and the patients will tell you. They say yes, and then it might need further testing physically; that is, actually do the exam and see if they have, on this Beighton scale, what the hyperflexibility score looks like. And if it is positive ... what we consider positive is five and above, five out of nine ... then those would candidates for a comprehensive DNA testing, whether it's related to cardiomyopathies, but I think connective tissue collection genes. Like I say, there's roughly 70 of these genes out there now that we test for in the commercial clinical laboratory setting. That should be monitored, as well as adding other genes if need be. So I'd encourage that.                              Physical examination number one. If it's positive, then check into a DNA panel for these types of disorders. It could help long-term for the care and outcome of the patient. Dr. Ferguson:    Yeah. I do think that's really important from the patient perspective and then, if more of these cases start being reported, I think it's very interesting also from the research perspective to find out what are the mechanisms that are potentially linking these mutations to cardiac disorders which have- [crosstalk] Dr. Butler:          That's true, and also realize that a lot of these patients have hypotension, and that can lead to some complications before, during and after surgical intervention, too. Dr. Ferguson:    Yeah. Dr. Butler:          So that's important to realize. Dr. Ferguson:    Very important. Yeah. So thank you for telling us about this interesting case and for raising this. I think it's an important issue and I'm sure a lot of the cardiologists and clinicians listening will start to look out for connective tissue disorders in their own patients. Dr. Butler:          I think, first thing is just ask questions. Are you hyperflexible? And they'll tell you. It's something that is very obvious to the patient. It will be obvious to the physician once he or she puts their hands on the patient, examine the patient, they realize, "Oh, this patient really is quite hyperflexible, digits and arms and knees and elbows," et cetera, et cetera. But, just ask the question, are they hyperflexible? If they say no, then the connective tissue is lower. It still could be. There could still be some aneurysms, those kind of things going on because there's, like I say, there's 70 genes, and there's six types of Ehlers-Danlos, so there's many other conditions out there that kind of look like an Ehlers-Danlos, but they're not. They may have another gene involving protein that's related to connective tissue, but not in the Ehlers-Danlos group of disorders or genes. Still could play a role. Could be similar. They may [inaudible] aneurysms, and that's important to know before they get into the procedures, too. Dr. Ferguson:    Yeah, really important, really interesting. Thank you so much for joining us.                              Thanks, everyone, for listening. And I wish you all the best for the holiday season, and a very happy new year. We're looking forward to bringing you lots more in 2019.                              This podcast was brought to you by Circulation: Genomic and Precision Medicine, and the American Heart Association Council on Genomic and Precision Medicine. This program is copyright American Heart Association, 2018.  

“We need to think differently about how we invest in our country programs, and what outcomes we are interested in,” said Dr. Koki Agarwal, director of the U.S. Agency for International Development (USAID)’s flagship Maternal and Child Survival Program (MCSP) and a Vice President with Jhpeigo, at a recent Wilson Center event. USAID’s “Acting on the Call” report recommended 29 evidence-based maternal health interventions, though Kelly Saldaña from USAID’s Bureau of Global Health said that with enough research and data, there are likely many more. “There’s a need to study further interventions…to have a better understanding of how we can link health systems directly to the outcomes we are trying to achieve.” To improve maternal, child, and adolescent health systems globally, we need to “have the ability to use that data to make changes within a health system,” said Dr. Agarwal. Strategic partnerships are essential to building stronger health systems. Donors, in tandem with their country partners, have to bring all the players together, said Dr. Agarwal: “Bringing in that partnership, understanding what is happening across the country at the onset, is a much more successful way of building a sustainable program at the country level.” Supporting country leaders to strengthen health systems is a crucial part of development partners’ jobs, said Mary Taylor, a professor at the Arctic University of Norway. “Country leadership is a process.”

Carolyn Lam:                      Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. I am so excited to be discussing the diabetic HFpEF or heart failure with a preserved ejection fraction phenotype, with world experts and new insights from the I-PRESERVE Trial. That will just be in a moment and here are your summaries first.                                                 The first paper in this issue is a systematic review and meta-analysis of risk factors for Co-Arctation of the Aorta on pre-natal ultrasound. In this paper by first author Dr. Familiari and corresponding author Dr. D'Antonio and colleagues from Arctic University of Norway, the authors performed a systematic review of 12 studies on 922 fetuses with echo-cardiography, and found that those with a post-natal diagnosis of co arctation had significant differences in several cardiac morphological parameters compared to cases without co arctation. The presence of a co arctation shelf, or hypoplastic arch, was associated with a significantly increased risk of co arctation. Furthermore, they reported multi-parametric diagnostic models that were associated with an increased detection rate. Thus, this paper tells us that assessment of left inflow and outflow tracts prenatally may help in stratifying the risk of co arctation.                                                 The next paper reports pre-clinical data that truly represents a paradigm shift in our understanding of vascular resident endothelial progenitors in tissue regeneration. In this paper by first author Dr. Patel, corresponding author Dr. [Cossroterrani 00:02:00], and authors from Royal Brisbane and Women's Hospital in Australia, the authors studied protein expression levels of common endothelial markers in mice using flow cytometry. They discovered an endovascular progenitor cell in vivo that is present in normal endothelium in the aorta and lungs and activated in vessel walls during various endogenic situations, such as in the placenta, skin wound healing, and tumors. They further define at a molecular level an entirely novel endothelial hierarchy from an endovascular progenitor cell to a mature different-shaded endothelial cell via complete RNA sequencing. They further clarify the linage of endothelial progenitors in their origin by using bone marrow transplantation and vascular-specific, lineage-tracing mouse models, showing that the endovascular progenitor cells were derived neither from bone marrow nor from hematopoietic progenitors. This discovery of an endovascular progenitor cell will have significant implications for the development of endothelial progenitors as a cell therapy.                                                 The next paper addresses the chicken or egg question regarding the association between obesity and atrial fibrillation, and this is done using Mendelian randomization to define a causal association between body mass index and atrial fibrillation. In this study by Dr. Chatterjee and colleagues from Massachusetts General Hospital, the authors looked at more than 50,000 European individuals without atrial fibrillation at baseline and showed that genetic variance associated with increasing body mass index were significantly associated with an increased risk of atrial fibrillation. The association between genetically determined obesity and atrial fibrillation persisted even after adjustment for traditional atrial fibrillation risk factors, such as hypertension, diabetes, coronary artery disease, and heart failure. Taken together, these data are consistent with a causal association between increasing body mass index and incident atrial fibrillation. These findings therefore support the primordial prevention of obesity as a significant public health target to combat the expanding global burden of atrial fibrillation.                                                 The last paper provides contemporary estimates of the stroke burden in China, a country which bears the biggest stroke burden in the world. In this paper by doctors Wang and Fagen from the Capital Medical University in Beijing, China and Auckland University of Technology in New Zealand, and colleagues, the authors reported results of a nationally represented door-to-door survey conducted in 2013 in 155 urban and rural centers in 31 provinces in China, totaling 480,687 adults. They found that the age standardized prevalence was 1,115 per 100,000 people, incidence rate was 247 per 100,000 person years, and mortality rates were 115 per 100,000 person years. The stroke prevalence estimates in 2013 were greater than those reported in China three decades ago, especially among the rural residents. Finally there was a north to south gradient of stroke in China, with the greatest burden observed in the northern and central regions. Well, that wraps it up for our summaries. Now for our discussion.                                                 For our featured discussion today, we are talking about my favorite topic and of course that is HFpEF, or heart failure with preserved ejection fraction, and I am so thrilled to have with us today Dr. John McMurray from University of Glasgow, who's the corresponding author of our featured paper referring to diabetes in patients with HFpEF and really talking about the novel results from the I-PRESERVE Trial. Welcome, John! John McMurray:               Thank you Carolyn, it's always a pleasure to speak to you. Carolyn Lam:                      Oh, I have been waiting for this one, and I'm so excited I don't know where to begin, but how about with this? Diabetes and HFpEF, first of all, haven't we spoken to death about co-morbidities in HFpEF? And secondly, what makes this paper special? Because we've heard about diabetes and HFpEF from CHARM, from DIG, from Relax, so tell us: why the interest in diabetes and HFpEF? John McMurray:               Sure, Carolyn. I think you and I have been interested in diabetes and heart failure, that terrible combination, for a long time. But I think there's a lot more interest in it today because, of course, we've had several new clinical trials with interventions to lower blood glucose that have showed both beneficial and potentially harmful effects on the development of heart failure. But really what these trials have highlighted is just how common heart failure is as a complication of diabetes. And we strongly suspect, though we don't know for sure of course, but we strongly suspect that most of that heart failure developing amongst patients with diabetes is probably heart failure with preserved ejection fractions. So, I think the context currently is that what's different about our study compared to the ones that you mentioned is that in I-PRESERVE we measured a number of things that were not available in, particularly, the large clinical trials previously. So, in I-PRESERVE we measured natriuretic peptides, we looked at health-related quality of life, and maybe most importantly of all we had a large echo-cardiographic sub study. So I-PRESERVE is quite different than DIG-Preserved and CHARM-Preserved, and of course a lot larger than the RELAX HFpEF study. Carolyn Lam:                      I was the associate editor managing your paper and I was so excited about this that I invited an editorial as well by Brian Lindman, and he's got this beautiful table that summarizes what your study really adds to the literature, and I think it's so critical. Could you start by summarizing? What are the main findings? John McMurray:               Well, I-PRESERVE, as you know, was a trial of just over 4,000 individuals with HFpEF defined clinically and with an ejection fraction of 45% or above. There was actually a trial comparing the angiotensin receptor-blocker [inaudible 00:09:17] placebo, though in fact there is no difference in morbidity and mortality between those two treatment groups. So we've looked, as you said, at the patients who had diabetes and compared those to the patients who didn't have diabetes. I think there was some very interesting novel information; if you look at the two subsets of patients, they actually don't differ in terms of age and sex and, importantly, in left ventricular ejection fraction.                                                 But there are other differences that you would expect; for example, many more of the patients with diabetes were obese. But interestingly, and despite that, the patients with diabetes had higher, significantly higher, NT-proBNP levels. So as you know, obesity tends to be associated with lower rather than higher natriuretic peptide levels, so here we were finding higher natriuretic peptide levels in a subset of patients who were actually, by and large, more obese. And there was no difference in other things that might have accounted for that difference; natriuretic peptides, for example, there was no difference in the proportion of patients who had atrial fibrillation.                                                 So that was important, and that's also important when we come to think of outcomes because of course the previous studies reporting worse outcomes in patients with diabetes had not adjusted for natriuretic peptides because they by and large weren't available in the large prior trials. So that, of course, could have accounted for some of the worse outcome.                                                 Some of the other things, features, maybe to pick out in terms of baseline characteristics ... one was that these patients had many more features of congestion, so patients with diabetes had more edema, more often had a raised jugular venous pressure and so on, and that's interesting given some of the recent clinical trial data that we might come back to. And even though the [inaudible 00:11:22] class distribution was not different between patients with diabetes and those without, what was very different was health-related quality of life, which was much worse in patients with diabetes than those without. Now you could if you chose to, Carolyn, look at that as saying that physicians weren't assessing worse functional status or symptomatic status in the patients with diabetes, but the patients were certainly self-reporting a much worse health-related quality of life.                                                 So those were the, sort of, clinical characteristic differences. We did, as I said, have an echo-cardiographic sub study. There were 745 patients in total in the trial who had a detailed echo study, and there were perhaps more modest differences than I might have expected (and I'd be interested in your opinion about this) in patients with diabetes. So they had a somewhat greater, statistically significantly greater left ventricular mass, they had increased early diastolic mitral inflow velocity through E, they certainly had increased E over E prime increased left atrial areas, so there was some left ventricular remodeling and there was some evidence of increased left ventricular filling pressure, maybe diastolic disfunction. But the differences were not very striking; they were there, and as I said previously, ejection fraction (which most of us regard as perhaps not a very good measure of systolic function) was similar between the two groups. We didn't look at more sophisticated and [inaudible 00:13:09] measures of systolic functions so those could have been different, we just don't know.                                                 So that's the baseline clinical features and baseline echo-cardiographic findings. And then, of course, we followed these patients for a median of just over four years and what we found was that the cardiovascular and all cause mortality was about twice as high in patients with diabetes as in those without. And if you adjust for conventional clinical variables, including NT-proBNP, which is individually the most powerful predictor of outcome, you only very slightly attenuate that greater risk associated with diabetes. The risk of heart failure and hospitalization was also about doubled in an unadjusted analysis, but that was more attenuated in the adjusted analysis. But you've also got to remember that, of course, the patients with diabetes were not surviving as long, so the very fact that they had a substantially higher risk of heart failure and hospitalization despite a shortened longevity is important.                                                 Then lastly, again I think a fairly unique aspect of this study was that we then added the echo-cardiographic findings into the multi-variable model [inaudible 00:14:33] because it was only a subset of patients in which we had echo-cardiographic measurements. The statistical reliability of this is not as robust as in the main model, but what we saw was that there was more attenuation of the risk associated with diabetes when you added in the remodeling and diastolic dysfunction findings that we saw in the echo-cardiographic sub study. So that's a summary, I think, of the key points. Carolyn Lam:                      John, I was really impressed and struck by the consistency of the message, which is what I really appreciated. What you added to the field was this consistent message that the diabetic HFpEF just had more signs of fluid overload in general, be it clinical, be it by NT-proBNP, be it by echo. And I thought that was something you said it was a moderate difference by echo; it was enough to be convincing to me, and I really appreciated that. The fact that adding the echo findings attenuated the significance ... you know we went back and forth about that quite a bit together, didn't we? John McMurray:               We did. Carolyn Lam:                      I think at the end it is consistent, it is useful information. It tells me that perhaps some of these outcomes are mediated by this access fluid, to me, at least part of it. And I think that is how we ended up expressing it in the final paper. John McMurray:               I think you are absolutely spot on, Carolyn, because I don't think I had anticipated that the features of congestion would be so different. And you are correct in that, of course, correlates very well with natriuretic peptides, with the left atrial enlargement and so on.                                                 And then of course (and this is clearly extrapolation) but then of course it makes one wonder about some of the trials with diabetes drugs that we've seen. The TZDs, glycosomes, which calls a little bit of fluid retention, of course precipitating heart failure, and then the opposite recently with the SGLT2 inhibitors which of course are diuretics, and those drugs preventing the development of heart failure.                                                 And it does make me wonder if the diabetic phenotype maybe was a little bit of renal dysfunction, some subtle renal dysfunction, is a sodium and water avid phenotype state and that it doesn't take very much to tip those patients into frank heart failure and perhaps we need to think (and I think you might have been alluding to it) think about insuring that we adequately diurese these patients given that in this study where people were supposed to be optimally treated, clearly there was still a lot of evidence of residual fluid overload. Carolyn Lam:                      I absolutely agree, and yes you read my mind that I was going to allude to the implications for therapies that have a diuretic effect, you know, like the SGLP2 inhibitors and in fact this was discussed in Brian Lindman's editorial, which is a must read.                                                 Just another question though. What do you think of peripheral mechanisms contributing to all this? John McMurray:               Yeah, obviously there is the kidney aspect that we saw a relatively small difference in estimated GFR. Of course that only tells you one aspect of renal function and the nephron in diabetes may well be sodium avid maybe more likely to retain water. So certainly the kidney as a peripheral mechanism might be very important.                                                 And then of course the blood vessels, I mean there's no question that patients with diabetes have more abnormal endothelial function probably have got enhanced vascular stiffness. And of course we know from a long time ago at least in HFrEF (I'm not so sure about HFpEF) but in HFrEF there's evidence that some of the vascular stiffness you see in patients with HFrEF is actually due to sodium in the vessel wall and there's some beautiful old-style clinical physiology experiments showing that if you diurese patients with HFrEF you restore vasodilation you restore basal motor responsiveness. It could also be true in HFpEF though of course patients with HFpEF and many other reasons to have vascular stiffness.                                                 So yes, peripheral mechanisms may well be important. Your humoral abnormalities may be more pronounced in patients with HFpEF and diabetes compared to those without diabetes. We don't know because I'm not sure that's been measured very often. Certainly natriuretic peptides are, but what about things like the angiotensin system and arginine/vasopressin and the sympathetic nervous system. You know, there's still so much to study looking at patients with heart failure with and without diabetes because they're really quite distinct. And whatever's going on it makes a big difference the way those patients feel, what they can do, and what happens to them. Carolyn Lam:                      Yeah, and your study really establishes that. Congratulations once again John, it's just been such a delight chatting with you. John McMurray:               Likewise, Carolyn. Carolyn Lam:                      Listeners, you heard it right here on Circulation on the Run. Don't forget to tell all your friends about this podcast and turn in next week!                                                  

Lisa Stevenson‘s new book opens with two throat-singing women and one listening king. Whether we hear them sitting down to a normal night’s dinner (as the women) or stalking the pages of a short story from Italo Calvino’s Under the Jaguar Sun (as the king), listening to these voices can potentially transform our notion of listening itself, as well as our understanding of what a “self” is and could be. Life Beside Itself: Imagining Care in the Canadian Arctic (University of California Press, 2014) shows us this by exploring formulations and practices of life, death, and care in a history and ethnography of Canadian policies and attitudes toward the Inuit during two epidemics, a tuberculosis epidemic (1940s-early 1960s) and a suicide epidemic (1980s-present). In juxtaposing those two cases, the book considers different forms of “care,” bureaucratic and otherwise. In her archival and ethnographic research, Stevenson works as a collector of images, paying careful attention to the ways that they give meaning to life itself, even and especially amid conditions of uncertainty and confusion. The first three chapters of the book trace the practices of anonymous care that characterized the two epidemics in question, considering how the Canadian North has functioned as a massive laboratory for transforming Inuit into Canadian citizens. Whether the biopolitical project operated on tubercular or suicidal subjects, Inuit people were conceptualized as serialized bodies that needed to be brought back to health. Life Beside Itself shows that despite this, Inuit were never fully made into biopolitical subjects: instead, we come to know the friends and acquaintances that animate Stevenson’s work as they cultivate multiple forms of life and of care. This is a beautiful and thoughtful book that will reward a wide range of readers, whether they come to it with an interest in health care and its histories, in the Canadian North, in forms of life and death, or simply in a moving and generously narrated story. Learn more about your ad choices. Visit megaphone.fm/adchoices

Lisa Stevenson‘s new book opens with two throat-singing women and one listening king. Whether we hear them sitting down to a normal night’s dinner (as the women) or stalking the pages of a short story from Italo Calvino’s Under the Jaguar Sun (as the king), listening to these voices can potentially transform our notion of listening itself, as well as our understanding of what a “self” is and could be. Life Beside Itself: Imagining Care in the Canadian Arctic (University of California Press, 2014) shows us this by exploring formulations and practices of life, death, and care in a history and ethnography of Canadian policies and attitudes toward the Inuit during two epidemics, a tuberculosis epidemic (1940s-early 1960s) and a suicide epidemic (1980s-present). In juxtaposing those two cases, the book considers different forms of “care,” bureaucratic and otherwise. In her archival and ethnographic research, Stevenson works as a collector of images, paying careful attention to the ways that they give meaning to life itself, even and especially amid conditions of uncertainty and confusion. The first three chapters of the book trace the practices of anonymous care that characterized the two epidemics in question, considering how the Canadian North has functioned as a massive laboratory for transforming Inuit into Canadian citizens. Whether the biopolitical project operated on tubercular or suicidal subjects, Inuit people were conceptualized as serialized bodies that needed to be brought back to health. Life Beside Itself shows that despite this, Inuit were never fully made into biopolitical subjects: instead, we come to know the friends and acquaintances that animate Stevenson’s work as they cultivate multiple forms of life and of care. This is a beautiful and thoughtful book that will reward a wide range of readers, whether they come to it with an interest in health care and its histories, in the Canadian North, in forms of life and death, or simply in a moving and generously narrated story. Learn more about your ad choices. Visit megaphone.fm/adchoices

Lisa Stevenson‘s new book opens with two throat-singing women and one listening king. Whether we hear them sitting down to a normal night's dinner (as the women) or stalking the pages of a short story from Italo Calvino's Under the Jaguar Sun (as the king), listening to these voices can potentially transform our notion of listening itself, as well as our understanding of what a “self” is and could be. Life Beside Itself: Imagining Care in the Canadian Arctic (University of California Press, 2014) shows us this by exploring formulations and practices of life, death, and care in a history and ethnography of Canadian policies and attitudes toward the Inuit during two epidemics, a tuberculosis epidemic (1940s-early 1960s) and a suicide epidemic (1980s-present). In juxtaposing those two cases, the book considers different forms of “care,” bureaucratic and otherwise. In her archival and ethnographic research, Stevenson works as a collector of images, paying careful attention to the ways that they give meaning to life itself, even and especially amid conditions of uncertainty and confusion. The first three chapters of the book trace the practices of anonymous care that characterized the two epidemics in question, considering how the Canadian North has functioned as a massive laboratory for transforming Inuit into Canadian citizens. Whether the biopolitical project operated on tubercular or suicidal subjects, Inuit people were conceptualized as serialized bodies that needed to be brought back to health. Life Beside Itself shows that despite this, Inuit were never fully made into biopolitical subjects: instead, we come to know the friends and acquaintances that animate Stevenson's work as they cultivate multiple forms of life and of care. This is a beautiful and thoughtful book that will reward a wide range of readers, whether they come to it with an interest in health care and its histories, in the Canadian North, in forms of life and death, or simply in a moving and generously narrated story. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Lisa Stevenson‘s new book opens with two throat-singing women and one listening king. Whether we hear them sitting down to a normal night’s dinner (as the women) or stalking the pages of a short story from Italo Calvino’s Under the Jaguar Sun (as the king), listening to these voices can potentially transform our notion of listening itself, as well as our understanding of what a “self” is and could be. Life Beside Itself: Imagining Care in the Canadian Arctic (University of California Press, 2014) shows us this by exploring formulations and practices of life, death, and care in a history and ethnography of Canadian policies and attitudes toward the Inuit during two epidemics, a tuberculosis epidemic (1940s-early 1960s) and a suicide epidemic (1980s-present). In juxtaposing those two cases, the book considers different forms of “care,” bureaucratic and otherwise. In her archival and ethnographic research, Stevenson works as a collector of images, paying careful attention to the ways that they give meaning to life itself, even and especially amid conditions of uncertainty and confusion. The first three chapters of the book trace the practices of anonymous care that characterized the two epidemics in question, considering how the Canadian North has functioned as a massive laboratory for transforming Inuit into Canadian citizens. Whether the biopolitical project operated on tubercular or suicidal subjects, Inuit people were conceptualized as serialized bodies that needed to be brought back to health. Life Beside Itself shows that despite this, Inuit were never fully made into biopolitical subjects: instead, we come to know the friends and acquaintances that animate Stevenson’s work as they cultivate multiple forms of life and of care. This is a beautiful and thoughtful book that will reward a wide range of readers, whether they come to it with an interest in health care and its histories, in the Canadian North, in forms of life and death, or simply in a moving and generously narrated story. Learn more about your ad choices. Visit megaphone.fm/adchoices