Podcasts about mineral research

Was man teilweise über Vitamin D hört, klingt fast zu schön, um wahr zu sein. Andererseits deuten hunderte verschiedener Forschungsarbeiten darauf hin, dass Vitamin D zur Vorbeugung einer Reihe von Krankheiten beitragen kann – darunter Osteoporose, Depression, Autoimmun- und Herz-Kreislauf-Erkrankungen. Ärzte empfehlen es. Gesundheits- und Fitnesspodcaster sprechen darüber. Vielleicht geht Dir sogar Deine Lieblingstante damit auf die Nerven. Bei all dem Hype ist die Frage berechtigt: "Solltest Du Vitamin D einnehmen?" Hier sind die Antworten – und die neuesten Fakten über ein faszinierendes Vitamin, das ein wahrer Verwandlungskünstler ist. ____________ *WERBUNG: KoRoDrogerie.de: 5% Ermäßigung auf alles mit dem Code „FMM“ beim Checkout. ____________ Ressourcen zur Folge: Literatur: Ratgeber Nahrungsergänzung – Mark Maslow (kostenlos auf MarathonFitness) Blut: Die Geheimnisse unseres flüssigen Organs* – Ulrich Strunz (Heyne) Vitamin D* – Uwe Gröber, Michael F. Holick (Wissenschaftl. Verlagsgesellschaft) Blutuntersuchung (Selbsttest): Vitamin D Test* von Medivere Präparate: D-Form 2.000 K2+* von FormMed D-Form 2.000 K2+ vegan* von FormMed ____________

Doctors Lisa and Sara talk to Dr Saadat Ahmed, ST5 in Geriatrics for a deep dive into Osteoporosis. We cover what it is, why it matters, what the risks factors are, who and how to assess for it, and what to do with results from FRAX and DXA scans. After a discussion on lifestyle options to help improve bone health, we ask advice on counselling patients around the pros and cons of taking Bisphosphonates including his advice on talking about the rarer side effects. We talk through a case and ask advice on how to reassess bone health after these initial conversations, and medications might have been started, including when to consider drug holidays.   Lots of excellent CPD here we feel. Enjoy and please share with any interested clinicians/trainees as you see fit.   Useful resources:  Osteoporosis - Prevention of Fragility Fractures NICE CKS Guidelines (updated Apr 2023): https://cks.nice.org.uk/topics/osteoporosis-prevention-of-fragility-fractures/ FRAX Calculator UK (Link from National Osteoporosis Guideline Group UK: https://frax.shef.ac.uk/FRAX/tool.aspx?country=1 WHO Falls Management: https://www.who.int/news-room/fact-sheets/detail/falls National Osteoporosis Guideline Group UK: https://www.nogg.org.uk/full-guideline/section-4-intervention-thresholds-and-strategy https://www.nogg.org.uk/full-guideline/section-7-strategies-management-osteoporosis-and-fracture-risk SIGN Scottish Osteoporosis Guidelines (discussion of evidence for links between PPIs and Osteoporosis on page 27): https://www.sign.ac.uk/media/1812/sign-142-osteoporosis-v3.pdf Osteonecrosis of the Jaw relative risk discussed on page 37 of National Osteoporosis Guideline Group UK: https://www.nogg.org.uk/sites/nogg/download/NOGG-Guideline-2021-g.pdf Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus, Journal of Bone and Mineral Research. Khan A et al 2015: https://pubmed.ncbi.nlm.nih.gov/25414052/ Flow Chart for Oral Bisphosphonates long term treatment and monitoring NOGG Guidelines: Page 35: https://www.nogg.org.uk/sites/nogg/download/NOGG-Guideline-2021-g.pdf Rubin KH, Rothmann MJ, Holmberg T, et al. Effectiveness of a two-step population-based osteoporosis screening program using FRAX: the randomized Risk-stratified Osteoporosis Strategy Evaluation (ROSE) study. Osteoporosis Int 2018; 29(3): 567-78. https://pubmed.ncbi.nlm.nih.gov/29218381/ Merlijn T, Swart KM, van Schoor NM, et al. The Effect of a Screening and Treatment Program for the Prevention of Fractures in Older Women: A Randomized Pragmatic Trial. J Bone Miner Res 2019; 34(11): 1993-2000. https://pubmed.ncbi.nlm.nih.gov/31220365/ Merlijn T, Swart KMA, van der Horst HE, Netelenbos JC, Elders PJM. Fracture prevention by screening for high fracture risk: a systematic review and meta-analysis. Osteoporosis Int 2020; 31(2): 251-7. https://pubmed.ncbi.nlm.nih.gov/31838551/ _____ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our quick anonymous survey here: https://pckb.org/feedback Email us at: primarycarepodcasts@gmail.com _____ This podcast has been made with the support of GP Excellence and Greater Manchester Integrated Care Board. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions.  The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.

Exercise both directly and indirectly influences detox. Exercise increases respiration, circulation and sweat production.  Exercise [in the sweet spot] also improves digestion and elimination so the toxins released can be removed. Exercise stimulates the lymphatic system (an integral part of the immune system for removal of metabolic waste and toxins).  The Lymphatic system relies on muscular contractions and body vibration to move fluids through the body.   Indirectly exercise supports natural detox by being a catalyst. Working out often helps increase water intake, improve nutrition choices and sleep. Are Some Exercises Better at Supporting Detox Than Others? Look, any movement and regularly doing so, even gentle yoga and walking support circulation. If you're able to exercise more intensely and sweat regularly your circulation is going to benefit more. Be mindful, this isn't a “more is better” thing. We need to move daily, and as much as more intense exercise will indeed get muscles and heart pumping to greater extent, we also need rest and recovery.  But there are movements traditionally suggested for lymphatic drainage and you may wonder why. Here are two:  Movement like rebounding which has been found to be good for lymph stimulation.  Here's the mechanism behind it. Rebounding causes the valves in the lymphatic system to open and close simultaneously increasing lymphatic flow by as much as 15% 2-3 minutes once or twice a day with feet staying in contact with surface Lymphatic flow requires 1) muscular contraction from exercise and movement, 2) gravitational pressure, and 3) internal massage to the valves of lymph ducts. Rebounding supplies all three methods of removing waste products from the cells and from the body. The gravitational pull could be provided from many exercises, but with rebounding repeated gravitational pull is provided rapidly over and over with landing.  However, there is not a lot of science suggesting that lymphatic drainage is indeed improved by rebounding. A small pilot study of 7 in 2018 seemed positive but with women with lower limb lymphedema.  Whole body Vibration Exercise Supports Natural Detox Whole body vibration activates 95% of the muscles in the entire body, creating a full-body circulation and lymphatic flow. This vibration therapy is better than massage because it uses the body's natural muscle movement to ensure full-body lymphatic drainage. The high levels of muscle contractions you'll experience on a Whole Body Vibration plate stimulate the lymph to FLUSH toxins by moving the lymphatic system, without more strenuous exercise. Even a short, seemingly light exercise session does this.  Lymphedema.net suggests a Hz of 10-30 for lymphatic drainage. Another site suggests 30-50 for optimal muscle stimulation. And 30Hz has been used in bone health studies successfully enhancing bone density.  The WBV I use is a Power Plate Move. It's a Medical Device Directive (MDD) Certified Medical device as well as a Class 1c US FDA-registered device.  Could Exercise Sabotage Your Detox?  Exercise mistakes might limit the positive effects of exercise on detox. Exercise is stress and too much stress will backfire. Exercise  causes inflammation. The inflammatory response to exercise supports a body's resilience – to stress and infection or illness. But if you are already at a tipping point for your body, that additional inflammation may put you over the edge. That is if it's too much for you at the moment. That doesn't have to mean you're attempting a marathon. But if you're already under stress, trying to maintain the same exercise you do when you're fully healthy and energetic, could be wrong.  Heads Up: There are Critics  You're going to read critics of the concept of lymph drainage. Be prepared! But I think for many of us, lymphatic drainage isn't the #1 reason for purchasing a whole body vibration tool. Even if lymph drain is a key benefit for you, it may be the bone density that is life saving because it's as a result of the treatments that were necessary. We all are going to have to continue to filter.  References:  Effect of 6-month Whole Body Vibration Training on Hip Density, Muscle Strength, and Postural Control in Postmenopausal Women: A Randomized Controlled Pilot Study. Journal of Bone and Mineral Research, 2004 Mar 22:19(3): 352-9. Epub 2003 Dec 22.  The Effect of Whole-Body Vibration on Lower Extremity Skin Blood Flow in Normal Subjects. Medical Science Monitor, Vol 13(2) pp. CR71-76, 20071. Cugusi L, Manca A, Serpe R, Romita G, Bergamin M, Cadeddu C, Solla P, Mercuro G; Working Group of Gender Cardiovascular Disease of the Italian Society of Cardiology. Effects of a mini-trampoline rebounding exercise program on functional parameters, body composition and quality of life in overweight women. J Sports Med Phys Fitness. 2018 Mar;58(3):287-294. doi: 10.23736/S0022-4707.16.06588-9. Epub 2016 Jul 21. PMID: 27441918. Resources:  Join the Cleanse: https://www.flippingfifty.com/cleanse Power Plate: https://www.flippingfifty.com/PowerPlate  Code: Flipping50  My Whole Body Vibration: https://www.flippingfifty.com/PowerPlate  Use Code: FLIPPING50 for a very special offer JUST for Flipping 50 community members. Seeing this Jan 2024? Don't miss it!! A massage gum PLUS 25% (normally 20% for our community) Other Episodes You Might Like:  The Genetics of Metabolism and Weight Loss for Women Over 40 https://www.flippingfifty.com/genetics-of-metabolism/ Perfection Detox for the Mindset of Midlife Success https://www.flippingfifty.com/perfection-detox/ Higher Metabolism with Thermogenesis: What's the Influence of Foods? https://www.flippingfifty.com/higher-metabolism/

Join L. Joseph Parker, a research physician, as we explore a recent study published in the Journal of Bone and Mineral Research. Discover how two compounds found in cannabis, cannabidiol (CBD) and cannabigerol (CBG), may revolutionize fracture healing and pain management. We'll delve into the study's findings, discuss the challenges doctors face in pain management, and explore the potential of these cannabinoids as alternatives to traditional medications. L. Joseph Parker is a research physician. He discusses the KevinMD article, "Cannabis compounds in fracture pain relief and healing." Careers by KevinMD is your gateway to health care success. We connect you with real-time, exclusive resources like job boards, news updates, and salary insights, all tailored for health care professionals. With expertise in uniting top talent and leading employers across the nation's largest health care hiring network, we're your partner in shaping health care's future. Fulfill your health care journey at KevinMD.com/careers. VISIT SPONSOR → https://kevinmd.com/careers Discovering disability insurance? Pattern understands your concerns. Over 20,000 doctors trust us for straightforward, affordable coverage. We handle everything from quotes to paperwork. Say goodbye to insurance stress – visit Pattern today at KevinMD.com/pattern. VISIT SPONSOR → https://kevinmd.com/pattern SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/j1CCmd Powered by CMEfy.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/NYY865. CME credit will be available until August 30, 2024.Can YOU Avoid Iatrogenic Harm? Understanding and Identifying Fibrodysplasia Ossificans ProgressivaIn support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and International Fibrodysplasia Ossificans Progressiva Association ,Progressive Osseous & Heteroplasia Association ,The American Society for Bone and Mineral Research. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresCo-Chair/PlannerRichard Keen, PhD, FRCP, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Grant/Research Support from Incyte; Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; and Regeneron Pharmaceuticals Inc.Speaker for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Co-Chair/PlannerEdna E. Mancilla, MD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc./Clementia Pharmaceuticals.Grant/Research Support from Incyte.Patient/PlannerErin Danzer has no financial interests/relationships or affiliations in relation to this activity.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/NYY865. CME credit will be available until August 30, 2024.Can YOU Avoid Iatrogenic Harm? Understanding and Identifying Fibrodysplasia Ossificans ProgressivaIn support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and International Fibrodysplasia Ossificans Progressiva Association ,Progressive Osseous & Heteroplasia Association ,The American Society for Bone and Mineral Research. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresCo-Chair/PlannerRichard Keen, PhD, FRCP, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Grant/Research Support from Incyte; Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; and Regeneron Pharmaceuticals Inc.Speaker for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Co-Chair/PlannerEdna E. Mancilla, MD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc./Clementia Pharmaceuticals.Grant/Research Support from Incyte.Patient/PlannerErin Danzer has no financial interests/relationships or affiliations in relation to this activity.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/NYY865. CME credit will be available until August 30, 2024.Can YOU Avoid Iatrogenic Harm? Understanding and Identifying Fibrodysplasia Ossificans ProgressivaIn support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and International Fibrodysplasia Ossificans Progressiva Association ,Progressive Osseous & Heteroplasia Association ,The American Society for Bone and Mineral Research. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresCo-Chair/PlannerRichard Keen, PhD, FRCP, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Grant/Research Support from Incyte; Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; and Regeneron Pharmaceuticals Inc.Speaker for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Co-Chair/PlannerEdna E. Mancilla, MD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc./Clementia Pharmaceuticals.Grant/Research Support from Incyte.Patient/PlannerErin Danzer has no financial interests/relationships or affiliations in relation to this activity.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/NYY865. CME credit will be available until August 30, 2024.Can YOU Avoid Iatrogenic Harm? Understanding and Identifying Fibrodysplasia Ossificans ProgressivaIn support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and International Fibrodysplasia Ossificans Progressiva Association ,Progressive Osseous & Heteroplasia Association ,The American Society for Bone and Mineral Research. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresCo-Chair/PlannerRichard Keen, PhD, FRCP, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Grant/Research Support from Incyte; Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; and Regeneron Pharmaceuticals Inc.Speaker for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Co-Chair/PlannerEdna E. Mancilla, MD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc./Clementia Pharmaceuticals.Grant/Research Support from Incyte.Patient/PlannerErin Danzer has no financial interests/relationships or affiliations in relation to this activity.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/NYY865. CME credit will be available until August 30, 2024.Can YOU Avoid Iatrogenic Harm? Understanding and Identifying Fibrodysplasia Ossificans ProgressivaIn support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and International Fibrodysplasia Ossificans Progressiva Association ,Progressive Osseous & Heteroplasia Association ,The American Society for Bone and Mineral Research. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresCo-Chair/PlannerRichard Keen, PhD, FRCP, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Grant/Research Support from Incyte; Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; and Regeneron Pharmaceuticals Inc.Speaker for Ipsen Biopharmaceuticals, Inc.; Kyowa Kirin Co., Ltd; Regeneron Pharmaceuticals Inc.; and UCB, Inc.Co-Chair/PlannerEdna E. Mancilla, MD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Ipsen Biopharmaceuticals, Inc./Clementia Pharmaceuticals.Grant/Research Support from Incyte.Patient/PlannerErin Danzer has no financial interests/relationships or affiliations in relation to this activity.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

Join me to learn about osteoporosis treatments with bone health expert Dr. Joy Wu.   We discuss lifestyle and medications that can halt bone loss, or even help rebuild bone. Dr. Wu also sheds light on the biology of bone and some of the factors that inform the optimal treatment for each patient.   Dr. Wu is a board-certified endocrinologist who specializes in osteoporosis and other bone mineral diseases. She treats patients and leads cutting-edge research at Stanford University, where she is Chief of the Division of Endocrinology, Gerontology and Metabolism and Vice Chair of Basic Science in the Department of Medicine.   This episode is the second of a two-part conversation. In part one, we discuss osteoporosis prevention.   Connect with Dr. Joy Wu Twitter @JoyYWu https://twitter.com/JoyYWu Stanford profile: https://profiles.stanford.edu/joy-wu   Resources Bone Health & Osteoporosis Foundation https://www.bonehealthandosteoporosis.org Osteoporosis Canada https://osteoporosis.ca Hormone Health Network of Endocrine Society https://admin.hormone.org American Society for Bone and Mineral Research (for physicians) https://www.asbmr.org/

Join me to learn about building and maintaining strong bones, with endocrinologist Dr. Joy Wu. Osteoporosis causes devastating bone fractures in millions of people every year, and there is a lot we can do to prevent it.   In this episode, we discuss the causes, consequences, and risk factors for osteoporosis and bone fractures. Dr. Wu sheds light on what's going in inside your bones and the role of diet, exercise, hormones and medications.   Dr. Wu is a board-certified endocrinologist who specializes in osteoporosis and other bone mineral diseases. She treats patients and leads cutting-edge research at Stanford University, where she is Chief of the Division of Endocrinology, Gerontology and Metabolism and Vice Chair of Basic Science in the Department of Medicine.   This episode is the first of a two-part conversation. In part two, we discuss osteoporosis treatment options.   Connect with Dr. Joy Wu Twitter @JoyYWu https://twitter.com/JoyYWu Stanford profile: https://profiles.stanford.edu/joy-wu   Resources Fracture Prevention Facts & Myths (Bone Health & Osteoporosis Foundation) https://www.bonehealthandosteoporosis.org/preventing-fractures/general-facts/ Osteoporosis Canada https://osteoporosis.ca Bone Health and Osteoporosis: A Report of the US Surgeon General https://pubmed.ncbi.nlm.nih.gov/20945569/ Hormone Health Network of Endocrine Society https://admin.hormone.org American Society for Bone and Mineral Research (for physicians) https://www.asbmr.org/   Related podcast episodes Navigating Menopausal Hormone Therapy (Dr. Carla DiGirolamo) https://fueledbyscience.com/podcast/carla-digirolamo-2/ Menopausal Hormone Therapy: Risks & Benefits (Drs Avrum Bluming & Carol Tavris) https://fueledbyscience.com/podcast/avrum-bluming-carol-tavris-1/ Menopausal Hormone Therapy: Setting The Record Straight (Dr. Avrum Bluming) https://fueledbyscience.com/podcast/avrum-bluming-2/

Antihypertensive and antioxidant activity in black beans National Polytechnic Institute (Mexico)   16 July 2022    Beans are one of the most important crops for the Mexican population due to its nutritional qualities. In fact, the country is one of the top 10 producers of this legume in the world, and several studies have reflected the correlation between consumption and decreased chronic degenerative diseases, cardiovascular diseases, obesity and diabetes.   Therefore, the National School of Biological Sciences of the National Polytechnic Institute (IPN-ENCB), conducted an investigation to evaluate the antioxidant and antihypertensive activity in black beans, and found that in addition to these qualities, proteins in the bean can remove heavy metals from the body.    The polytechnic research identified bioactive peptides in the legume that have a beneficial effect as antihypertensive and antioxidant, which could favor the prevention and treatment of cardiovascular diseases, with a specific effect on blood pressure and oxidative stress.    It was determined that fasolina and lectin hydrolysates (main proteins in the Jamapa black bean) had chelating activity (removal of heavy metals in the body) and, when hydrolyzed with pepsin-pancratin, they release peptides (amino acids) with antihypertensive and antioxidant effects.    Could Eating Fruit More Often Keep Depression At Bay? Aston University (UK), July 15, 2022 People who frequently eat fruit are more likely to report greater positive mental well-being and are less likely to report symptoms of depression than those who do not, according to new research from the College of Health and Life Sciences, Aston University The study found frequent fruit eaters had greater positive mental wellbeing The study surveyed 428 adults and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks and their psychological health The more often people ate fruit, the lower they scored for depression and the higher for mental well-being. Published in the British Journal of Nutrition, the study surveyed 428 adults from across the UK and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks, and their psychological health. People who frequently snacked on nutrient-poor savoury foods (such as crisps) were more likely to experience 'everyday mental lapses' (known as subjective cognitive failures) and report lower mental wellbeing. A greater number of lapses, was associated with higher reported symptoms of anxiety, stress and depression, and lower mental wellbeing scores.       Effect of Short-term Quercetin, Caloric Restriction in Late Life Effective to Counter Age-Related Oxidative Macromolecular Damage. Pondicherry University (India), July 13, 2022   According to news from Pondicherry, India, research stated, "Aging is characterized by gradual accumulation of macromolecular damage leading to progressive loss of physiological function and increased susceptibility to diverse diseases. Effective anti-aging strategies involving caloric restriction or antioxidant supplementation are receiving growing attention to attenuate macromolecular damage in age associated pathology." Research from Pondicherry University, "In the present study, we for the first time investigated the effect of quercetin, caloric restriction and combined treatment (caloric restriction with quercetin) on oxidative stress parameters, acetylcholinesterase and ATPases enzyme activities in the cerebral cortex of aged male Wistar rats.  Our results demonstrate that combined treatment of caloric restriction and quercetin significantly improved the age associated decline in the activities of endogenous antioxidant enzymes [such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] and glutathione (GSH), and nitric oxide (NO).  According to the news reporters, the research concluded: "Finally, we conclude that combined treatment of caloric restriction and quercetin in late life is an effective anti-aging therapy to counteract the age related accumulation of oxidative macromolecular damage."       How Drinking Soda on a Hot Day Can Damage Kidneys, Leading to Diabetes, Heart Disease University of Buffalo, July 18, 2022 Research demonstrates the acute deleterious effects soda can have on your kidney function when used to quench your thirst during exertion on a hot day. Drinking soda causes dehydration and raises markers for kidney disease when consumed after performing manual labor or exercise in 95-degree Fahrenheit weather. When you exert yourself in a hot environment, your body regulates blood pressure and conserves water by reducing blood flow to your kidneys. A sudden and steep drop in blood flow through your kidneys can cause acute kidney injury due to the fact that it reduces the amount of oxygen being delivered to your kidneys. Your diet has an overriding influence over the health of your kidneys, with sugar and excess protein topping the list of food components known to cause problems when consumed regularly. The study, published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, found soda caused dehydration and raised markers for kidney disease when consumed after performing manual labor in 95-degree F. weather. “The volunteers completed … a 30-minute treadmill workout followed by three different five-minute lifting, dexterity and sledgehammer swinging activities. After 45 minutes of exercise, the volunteers rested for 15 minutes … while drinking 16 ounces of either a high-fructose, caffeinated soft drink or water. After the break, they repeated the cycle three more times for a total of four hours. Before leaving the laboratory, the volunteers were given more of their assigned beverages to drink before consuming any further fluids. The volume was either 1 liter or a volume equal to 115% of their body weight lost through sweating if that amount was greater.” When volunteers drank soda, 75% of them had elevated levels of creatinine in their blood, a marker for kidney injury. Only 8% of participants in the water trial had elevated creatinine. When drinking soda, volunteers also had: A lower glomerular filtration rate, another marker for kidney injury Higher uric acid levels Mild dehydration Higher levels of vasopressin, an antidiuretic hormone that raises blood pressure       Black Seed Oil Extract Causes Oral Cancer Cells To Self-Destruct Institute of Biochemistry and Biotechnology (Taiwan), July 20, 2022      A range of chemotherapeutic options for treating cancer are available, however many of the treatments are themselves associated with significant morbidity and mortality. Today many cancer sufferers search for alternatives to conventional chemotherapy. Increasingly natural alternative options are becoming available, often with little or no side-effects and concrete science is proving the effects of many natural substances against cancer.   One substance which is increasingly making the headlines is thymoquinone, an active component of Nigella sativa or black seed oil. Scientists from the Institute of Biochemistry and Biotechnology, Taiwan, have found that this remarkable compound elicits cytotoxic effects on various squamous cancer cell lines through various mechanisms.  The study examined a highly malignant strain of squamous cell carcinoma, which was taken from various patients with oral cancer; this particular cancer type also causes many other cancers of the head and neck.   The cell lines were grown in a lab and treated with different concentrations of thymoquinone. The results showed that after just 24 hours of treatment there was a significant concentration-dependent cytotoxic effect on these cells. The study further examined why this was happening. Their findings are quite remarkable as they were able to demonstrate that thymoquinone was a potent inhibitor of oral cancer cell viability via two distinct anti-neoplastic mechanisms.     No bones about it: Cannabis may be used to treat fractures Tel Aviv University researcher finds non-psychotropic compound in marijuana can help heal bone fissures Tel Aviv University (Israel), July 19, 2022 A study published in the Journal of Bone and Mineral Research by Tel Aviv University and Hebrew University researchers explores another promising new medical application for marijuana. According to the research, the administration of the non-psychotropic component cannabinoid cannabidiol (CBD) significantly helps heal bone fractures. The study, conducted on rats with mid-femoral fractures, found that CBD -- even when isolated from tetrahydrocannabinol (THC), the major psychoactive component of cannabis -- markedly enhanced the healing process of the femora after just eight weeks. Undeniable clinical potential The same team, in earlier research, discovered that cannabinoid receptors within our bodies stimulated bone formation and inhibited bone loss. This paves the way for the future use of cannabinoid drugs to combat osteoporosis and other bone-related diseases. "We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue," said Dr. Gabet. "After being treated with CBD, the healed bone will be harder to break in the future." The researchers injected one group of rats with CBD alone and another with a combination of CBD and THC. After evaluating the administration of THC and CBD together in the rats, they found CBD alone provided the necessary therapeutic stimulus.   OCCUPY PEACE & FREEDOM RALLY INFO Saturday, July 23 -- 2:00 pm Kingston, NY (at the historical 4 corners -- Crown and John Streets) Speakers: Gerald Celente Judge Andrew Napolitano Gary Null Scott Ritter Phil Giraldi (former CIA official) Live music, food and drink

Today, Justin Beamis sits down with Dr. Benjamin Levi, M.D. to discuss his life, his research, and the incredible work he and his team at U.T. Southwest Medical are doing with the donations made by everyone who supports Sons of the Flag! Benjamin Levi, M.D., is an Associate Professor in the Department of Surgery at UT Southwestern Medical Center. He holds the Dr. Lee Hudson-Robert R. Penn Chair in Surgery and Plastic and Reconstructive Surgery and serves as Division Chief of Burn, Trauma, Acute and Critical Care Surgery. He specializes in acute and reconstructive burn surgery and scar reconstructive surgery. He is the author of more than 100 scholarly articles, including high-impact papers in Science Translational Medicine, Proceedings of the National Academy of Sciences, and Nature Communications, as well as chapters in a number of textbooks, including Greenfield's Surgery, Total Burn Care, Grabb and Smith's Plastic Surgery, and Trauma. He has delivered presentations worldwide, held numerous invited professorships, and serves as a permanent editor and ad hoc editor for journals in his area of research. Dr. Levi co-chairs the Reconstructive Special Interest Group of the American Burn Association. He is also a member of the American College of Surgeons, the American Council of Academic Plastic Surgeons, the American Society for Bone and Mineral Research, the American Society of Plastic Surgeons, the Association for Academic Surgery, the Reed O. Dingman Society, and the Plastic Surgery Research Council. Sponsored by Magnegrip and Tencate.    

There are only few people on the planet who understand bone better than Prof Peter Ebling. Professor Peter Ebeling, AO, is Head of the Department of Medicine in the School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences. He was also inaugural Director of the Australian Institute of Musculoskeletal Science (AIMSS). Professor Ebeling has 28,000+ citations; and has over 450 peer-reviewed publications, including in the New England Journal of Medicine, Science, Proceedings of the National Academy of Science and Journal of Bone and Mineral Research, 153 publications over the last 5 years. In 2015, Professor Ebeling was made an Officer in the Order of Australia for his distinguished service to medicine in the field of bone health. Professor Ebeling's research interests include musculoskeletal health and diseases; public health aspects of vitamin D; post-transplantation osteoporosis; osteoporosis in men; and biochemical bone turnover markers. Peter is clinically available as an Endocrinologist through the Jean Hailes for Women's Health Clinic in East Melbourne and also holds a role as head of the department of medicine for Monash University at Monash Health.   Show Sponsor: POLAR Polar are a sports technology company who build world class heart rate monitors and GPS watches for people who take their health, fitness and sports performance seriously. Polar have an incredible heritage. Headquartered in Finland they have been the global driving force behind scientific wearables for over 40 years. They are the pioneers in and world leaders in heart rate measurement technology. Their products provide you with 24/7 monitoring to enable you to plan better, train smarter, recover fully … so you can be at your physical best. Coming from the heart of the Nordics, they have the experience, insight, and history of quality, design and innovation which is unparalleled. Worn by some of the best athletes on the planet, we're very excited to have Polar as a partner here so you can also access their heart rate monitors, watches and training platform. As a starting bonus, the team at Polar are offering 15% off. If it's time for you to check out a new heart rate monitor or watch to help improve your performance, head across to Polar.com and use the code TPPS on selected products Join the The Physical Performance Show LEARNINGS membership through weekly podcasts | Patreon If you enjoyed this episode of The Physical Performance Show please hit SUBSCRIBE for to ensure you are one of the first to future episodes. Jump over to The Physical Performance Show - https://physicalperformanceshow.com/ for more details. Sponsor: Precision Hydration If you've ever struggled with hydration issues like cramp during long, hot sessions, it's worth checking out precisionhydration.com. Follow @Brad_Beer Instagram & Twitter The Physical Performance Show: Facebook, Instagram, & Twitter (@tppshow1) Please direct any questions, comments, and feedback to the above social media handles.

Nutrition is involved in making every part of our body, including our bones. Today we are going to discuss what foods support strong and flexible bones and also the foods that can cause weak fragile bones. 15 to 20 million people in the U.S. suffer from osteoporosis and according to the Natural Osteoporosis Foundation while 44 million Americans have low bone density. A study in the Journal of Bone and Mineral Research from the Mayo Clinic found that in the last 30 years, forearm fractures have increased by 32 percent in boys and 56% in girls. If you are concerned about the bone health of you or a family member, we have a bone-building plan for you! We believe your bones will be stronger and you will not have to endure a fracture as you age or when partaking in your favorite types of physical movement. Listen in for what to eat and what to avoid!

Nutrition is involved in making every part of our body, including our bones. Today we are going to discuss what foods support strong and flexible bones and also the foods that can cause weak fragile bones. 15 to 20 million people in the U.S. suffer from osteoporosis and according to the Natural Osteoporosis Foundation while 44 million Americans have low bone density. A study in the Journal of Bone and Mineral Research from the Mayo Clinic found that in the last 30 years, forearm fractures have increased by 32 percent in boys and 56% in girls. If you are concerned about the bone health of you or a family member, we have a bone-building plan for you! We believe your bones will be stronger and you will not have to endure a fracture as you age or when partaking in your favorite types of physical movement. Listen in for what to eat and what to avoid!

Our initial series, Pathways: ASBMR Stories of Discovery, is hosted by Dr. Michael Econs, Distinguished Professor at the Indiana University School of Medicine. Throughout this three part series, we speak with pioneers in discovery of FGF23. We explore dysregulation of FGF23 in renal failure, inhibiting FGF23 for treatment of XLH, and the interplay of FGF23 and iron.Episode one features a X-linked Hypophosphatemia-focused discussion with Dr. Thomas Carpenter. Dr. Carpenter has maintained a career-long involvement in metabolic bone diseases in children. He currently serves as director of the Yale Center for X-linked Hypophosphatemia (XLH) and as the Medical Director of the Yale Center for Clinical Investigation's Hospital Research Unit. His research interests center on the pathophysiology and development of therapy for XLH, the most common inherited form of rickets. He also has a major interest in the metabolism and function of vitamin D, and disorders related to vitamin D in children. He has published over 200 articles, reviews and chapters with a focus of metabolic bone diseases in children, and is currently an Associate Editor of the Journal of Bone and Mineral Research.Be sure to subscribe to tune in for future episodes. Thank you for joining us!

Today I talked to Lauren about her personal journey in to the ketogenic lifestyle, as well as how she helps her clients successfully achieve the switch also. Lauren Weiss is a behavioral nutritionist specializing in the low-carb and keto lifestyle. She worked as a nutrition scientist at the University of California, San Diego for over a decade and now owns a clinical nutrition practice in La Jolla, California. She has published scientific research on nutrition in journals such as The American Journal of Nutrition, Journal of Bone and Mineral Research, and The American Journal of Medical Genetics. Lauren has been following a low-carb lifestyle for over 20 years. Contact Lauren: La Jolla Nutritional Health 7590 Fay Avenue, Suite 204B La Jolla, CA 92037 Cell/text: (619) 997-6866 www.lajollanutritionalhealth.com lajollanutritionalhealth@gmail.com Contact: Tracey McBeath Web: https://www.traceymcbeath.com.au Facebook: https://www.facebook.com/traceymcbeat... Instagram: https://www.instagram.com/tracey_mcbe... Join the Low Carb Lifestyle Hub: https://www.lowcarblifestylehub.com Join Low Carb Melbourne on Facebook: https://www.facebook.com/groups/38715... Are you a health practitioner and interested in learning how to bring low carb in to your practice with confidence? The Nutrition Network has a number of programs to help. For GP's; Dietitians; Nurses and Health Coaches. The Nutrition Network is run by the Noakes Foundation. To learn more, click here: http://bit.ly/nutritionnetwork  

Rapha, Raíssa e João conversam sobre Osteoporose! Como diagnosticar? Qual é o manejo correto? Referências: 1- Overview of the management of osteoporosis in postmenopausal women. Uptodate 2021. Harold N Rosen, Marc K Drezner, Clifford J Rosen, Kenneth E Schmader, Jean E Mulder. 2- EASTELL, Richard et al. Pharmacological management of osteoporosis in postmenopausal women: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, v. 104, n. 5, p. 1595-1622, 2019. 3- CAMACHO, Pauline M. et al. American Association of Clinical Endocrinologists/American College of Endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis—2020 update. Endocrine Practice, v. 26, p. 1-46, 2020. 4- KANIS, John A. et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis international, v. 30, n. 1, p. 3-44, 2019. 5- BLACK, DM; et al. Postmenopausal Osteoporosis. NEJM, 2016 6- SHANE, E; et al. Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research, JBMR, Vol. 29, Nº1, 2014. 7- PEREZ, AD; et al. Treatment failure in osteoporosis, Osteoporos Int, 2012. 8- ADLER, RA; et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. JBMR, Vol. 31, Nº 1, 2016. 9- - BLACK, DM; et al. Postmenopausal Osteoporosis. NEJM, 2016 - AACE/ACE Clinical Practice Guidelines for the diagnosis and Treatment of Postmenopausal Osteoporosis - 2020 Update. 10- - SHANE, E; et al. Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research, JBMR, Vol. 29, Nº1, 2014. 11- PEREZ, AD; et al. Treatment failure in osteoporosis, Osteoporos Int, 2012. 12- ADLER, RA; et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. JBMR, Vol. 31, Nº 1, 2016. Minutagem (1:40) Divisão do episódio (2:18) Caso clínico (3:00)Abordagem inicial (4:20) Definição - critérios diagnósticos (9:15) Densitometria óssea (14:03) FRAX (20:00) Voltando ao caso (21:25) Rastreio (25:40) Caso Clínico 2 (32:40) Avaliação laboratorial (35:00) Tratamento e suplementação (39:30) Tratamento farmacológico (47:15) Reações adversas (51:00) Contraindicações (51:55) Relacionando com os casos (56:00) Terapia anabólico (59:56) Até quando usar os medicamentos? (1:03:22) Falha de tratamento (1:05:43) Salves (1:07:53) Respost do desafio da semana anterior (1:08:50) Desafio da semana

Professor Stuart Warden is an avid runner.  Academically and professionally Dr Stuart Warden serves as a Professor of Physical Therapy and the Associate Dean for Research within the Indiana University School of Health & Human Sciences. Professor Stu embarked on a Post Doctorate at the Australian Institute of Sport and Indiana University Department of Orthopaedic Surgery, following graduation from the University of Melbourne with a Physiotherapy Degree in 2001. Professor Warden's research interests focus on the form and function of the musculoskeletal system, in-particular the lifelong contribution of physical activity to skeletal health. Professor Stu has contributed to over 170 peer reviewed publications and currently serves as an Associate Editor for The Journal of Orthopaedic & Sports Physical Therapy and also as an Editorial Board Member for Bone, Journal of Bone and Mineral Research and the Journal of Science and Medicine in Sport. Professor Stuart Warden alongside colleagues Brent Edwards and Dr Rich Willy released a landmark commentary by way of a scientific paper titled "Preventing Bone Stress Injuries in Runners with Optimal Workload". It was published in February 2021 and it's a must read for any Coach, Athlete or Practitioner working in the field of endurance sports. In this episode we dive deep into its contents: What the author's mean by bone workload Optimal workload to induce skeletal adaptation The fact that not all athletes have good skeletons Why it is that distance running does not build good bones How we can use periodisation to help build more bone The effects of early specialisation with sport and the contribution to bone stress injury risk Why it is that optimising bone structure is critical and how it only develops before puberty How it is that we can positively affect our bone density and bone architecture through loading with multiple direction jumps and why it is only during puberty that this is possible How we can positively increase the robustness of our skeleton through bone centric exercises How we can try and minimise training errors to avoid the onset of a bone stress injury, a stress fracture a stress reaction or similar Show Sponsor: Precision Hydration If you've ever struggled with hydration issues like cramp during long, hot sessions, it's worth checking out precisionhydration.com. If you can't get to a test centre, then you can take their free online Sweat Test to get a personalized hydration strategy to test in training. As a listener of the show you can get 15% off your first order of Precision Hydration electrolytes and the new Precision Fuel range by using the code TPPS at the checkout at precisionhydration.com Join the The Physical Performance Show LEARNINGS membership through weekly podcasts | Patreon If you enjoyed this episode of The Physical Performance Show please hit SUBSCRIBE for to ensure you are one of the first to future episodes. Jump over to POGO Physio - www.pogophysio.com.au for more details Follow @Brad_Beer Instagram & Twitter The Physical Performance Show: Facebook, Instagram, & Twitter (@tppshow1) Please direct any questions, comments, and feedback to the above social media handles.

Episódio muito aguardado de Vitamina D finalmente chegou! Quem precisa repor? Como repor? Tudo isso nesse episódio trazido pelo Raphael Coelho, Iago Jorge e Marcela Belleza! Esse episódio foi em parceria com o Whitebook! Acesse o aplicativo que te ajuda de forma rápida com informação de confiança na hora que você mais precisa! Dose da ceftriaxone na meningite? Principais patógenos? Tem tudo isso lá! Clique no link para descobrir mais https://tinyurl.com/TdC-Whitebook Minutagem em breve. REFERÊNCIAS 1- Overview of Vitamin D. Uptodate 2021 Authors:Sassan Pazirandeh, MDDavid L Burns, MDSection Editors:Kathleen J Motil, MD, PhDMarc K Drezner, MDDeputy Editor:Jean E Mulder, MD 2- Calcium and vitamin D supplementation in osteoporosis. Uptodate 2021. Harold N Rosen, Clifford J Rosen, Kenneth E Schmader, Jean E Mulder 3- ARMAS, Laura AG; HOLLIS, Bruce W.; HEANEY, Robert P. Vitamin D2 is much less effective than vitamin D3 in humans. The Journal of Clinical Endocrinology & Metabolism, v. 89, n. 11, p. 5387-5391, 2004. 4- CAULEY, Jane A. et al. Serum 25‐hydroxyvitamin D and clinical fracture risk in a multiethnic cohort of women: The women's health initiative (WHI). Journal of Bone and Mineral Research, v. 26, n. 10, p. 2378-2388, 2011. 5- SANDERS, Kerrie M. et al. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. Jama, v. 303, n. 18, p. 1815-1822, 2010. 6- GILLESPIE, Lesley D. et al. Interventions for preventing falls in older people living in the community. Cochrane database of systematic reviews, n. 9, 2012. 7 - AMERICAN GERIATRICS SOCIETY WORKGROUP ON VITAMIN D SUPPLEMENTATION FOR OLDER ADULTS. Recommendations abstracted from the American geriatrics society consensus statement on vitamin D for prevention of falls and their consequences. Journal of the American Geriatrics Society, v. 62, n. 1, p. 147-152, 2014. 8- ROSS, A. Catharine et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. The Journal of Clinical Endocrinology & Metabolism, v. 96, n. 1, p. 53-58, 2011. 9- Vitamin D and extraskeletal health. Uptodate 2021. Roger Bouillon, Clifford J Rosen, Jean E Mulder, MD 10- EASTELL, Richard et al. Pharmacological management of osteoporosis in postmenopausal women: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, v. 104, n. 5, p. 1595-1622, 2019. 11- KANIS, John A. et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International, v. 30, n. 1, p. 3-44, 2019. 12- COSMAN, Felicia et al. Clinician's guide to prevention and treatment of osteoporosis. Osteoporosis international, v. 25, n. 10, p. 2359-2381, 2014. 13- RADOMINSKI, Sebastião Cézar et al. Diretrizes brasileiras para o diagnóstico e tratamento da osteoporose em mulheres na pós-menopausa. Revista Brasileira de Reumatologia, v. 57, p. s452-s466, 2017. 14- HOLICK, Michael F. et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, v. 96, n. 7, p. 1911-1930, 2011. 15- MANSON, J. E. et al. Vitamin D deficiency-is there really a pandemic. N Engl J Med, v. 375, n. 19, p. 1817-1820, 2016.

The cost of fracture & osteoporosis in Australia. This episode reports findings from a recent study published in the Journal of Bone & Mineral Research which shows how much fractures, osteoporosis and osteopenia cost the healthcare system. The main finding was the total direct cost of osteoporosis in Australia in 2017 was estimated to be $3.44 billion - ALOT OF MONEY!! For the full publication: https://onlinelibrary.wiley.com/doi/abs/10.1002/jbmr.3640 Contact us: Twitter: @DrAyseZ & @Sandroppa Email: bonebanter@gmail.com

R. Keith McCormick, DC, CCSP, is a chiropractic physician with a private practice in western Massachusetts, where he specializes in the nutritional management of patients with bone fragility and also in the treatment of sports injuries. Dr. McCormick studied Human Biology at Stanford University and earned his doctorate at the National College of Chiropractic. He is a member of the American Society for Bone and Mineral Research, the International Bone and Mineral Society, and the Institute for Functional Medicine. Dr. McCormick is a Certified Chiropractic Sports Physician with membership in the ACA Council on Sports Injuries and Physical Fitness. Sports have played a vital role throughout Keith McCormick's life. At Stanford, he competed on the varsity cross-country and fencing teams. As a junior, he was the silver medalist in the Modern Pentathlon World Championship. Then in 1975 he won the North American Championship and the following year was a member of the United States Olympic Team competing in the XXI Olympiad in Montreal. Dr. McCormick continues to compete at the elite level in triathlons of all distances including Ironmans such as the Ironman World Championships in Hawaii. His most recent accomplishments placed him 7th (AG) in the 2010 and 9th (AG) in 2011 70.3 Ironman Triathlon World Championships.

Bisher dachte man, dass die trabekuläre Struktur der Spongiosa für die Festigkeit des Knochens verantwortlich ist. So erklärte man auch Beispiele in der Architektur oder Technik, wobei der Knochen als Modell dazu diente (z.B. der Eiffelturm). Wenn man aber die Knochenfestigkeit am Femurknochen misst, nachdem die Spongiosa entfernt wurde, erkennt man sehr klar, dass nicht die Spongiosa, sondern die Kortikalis für die Knochenfestigkeit hauptverantwortlich ist. Univ. Prof. Dr. Gerold Holzer von der Univ. Klinik für Orthopädie in Wien berichtet in den Billrothhaus News über die von ihm durchgeführten Experimente, die ein neues Kapitel für die Osteoporosediagnostik und -therapie einläuten. Die Ergebnisse wurden ausführlich in der Märzausgabe des Journal of Bone and Mineral Research veröffentlicht und waren am 22.04. Thema einer Wissenschaftlichen Sitzung der Gesellschaft der Ärzte.