POPULARITY
4 episodes with caloric restriction
5 episodes with caloric restriction
4 episodes with caloric restriction
3 episodes with caloric restriction
3 episodes with caloric restriction
2 episodes with caloric restriction
2 episodes with caloric restriction
3 episodes with caloric restriction
3 episodes with caloric restriction
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Allison, Director of the USDA Children's Nutrition Research Center at Baylor College of Medicine. Together, they examine what it takes to build public trust in nutrition and longevity science, and why clear, reproducible evidence matters more than ever. David highlights how public perception and scientific rigor can drift apart, especially in fields crowded with strong opinions and shifting trends.David shares sharp insights on weight management, challenging the idea that slow and steady always wins. He explains the “dentistry model” of weight loss, where maintenance matters more than one-time fixes, and explores why most people regain weight without ongoing support. The discussion cuts through assumptions about exercise, protein, and processed foods, showing where animal research aligns, or fails to align, with human studies.Throughout, David pushes for honest communication and transparency in science. He urges listeners to question hype, look past nutrition fads, and recognize the real limits of current evidence. The episode offers practical wisdom for anyone who wants to approach health, nutrition, and longevity with both curiosity and caution. Guest-at-a-Glance
I put the live video here - 01192026.fastingbot.comYoutube Channels:Conner with Honor - real estateHome Muscle - fat torchingFrom first responder to real estate expert, Connor with Honor brings honesty and integrity to your Santa Clarita home buying or selling journey. Subscribe to my YouTube channel for valuable tips, local market trends, and a glimpse into the Santa Clarita lifestyle.Dive into Real Estate with Connor with Honor:Santa Clarita's Trusted Realtor & Fitness EnthusiastReal Estate:Buying or selling in Santa Clarita? Connor with Honor, your local expert with over 2 decades of experience, guides you seamlessly through the process. Subscribe to his YouTube channel for insider market updates, expert advice, and a peek into the vibrant Santa Clarita lifestyle.Fitness:Ready to unlock your fitness potential? Join Connor's YouTube journey for inspiring workouts, healthy recipes, and motivational tips. Remember, a strong body fuels a strong mind and a successful life!Podcast:Dig deeper with Connor's podcast! Hear insightful interviews with industry experts, inspiring success stories, and targeted real estate advice specific to Santa Clarita.
Welcome to the latest episode of L.I.F.T.S, your bite‑sized dose of the Latest Industry Fitness Trends and Stories. In this episode of, hosts Matthew Januszek and Mohammed Iqbal sit down with Dr. Bill Andrews: molecular geneticist, inventor, and telomere pioneer to explore what actually causes human aging and whether it can be slowed, stopped, or even reversed. Key topics covered: What telomeres are and why they determine human lifespan. Why aging isn't random, but biologically programmed. The real relationship between telomeres and cancer. How exercise, inflammation, and lifestyle impact cellular aging. Why most anti-aging products fail scientific scrutiny. The role of telomerase in extending cellular life. What longevity influencers often get wrong. Practical habits that may slow biological aging.
BONUS Episode:Das ist eine besondere Modern Medicine Episode. Es ist meine erste Folge auf Englisch und damit ein Gespräch, das dir direkte Einblicke in die internationale Longevity Forschung gibt.Ich hatte die Ehre mit Prof. Matt Kaeberlein zu sprechen, ein US amerikanischer Biologe und einer der prägenden Forscher im Bereich der molekularen Alterungsmechanismen.Wir sprechen darüber, wie sinnvoll gängige Tests zur Bestimmung des biologischen Alters wirklich sind, warum mTOR als zentraler Stoffwechsel Schalter Alterungsprozesse mitsteuert und wie Ernährung, Kalorienrestriktion und Proteinzufuhr diese Signalwege beeinflussen.In dieser Folge erfährst du:
In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We explain how to improve hormone levels across the lifespan in both men and women using behavioral, nutritional and exercise-based tools. We also discuss common clinical topics, including hormone testing, PCOS, hair loss, testosterone replacement therapy (TRT) and peptides, focusing on potential benefits, tradeoffs and risks. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui: https://mauinuivenison.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Kyle Gillett (00:00:36) Hormone Health; Women vs Men, Tool: Hormone Testing (00:02:35) Tool: Big 6 Lifestyle Pillars to Optimize Hormone Health (00:04:32) Sponsor: AG1 (00:06:17) Diet, Individualization; Bloodwork & Frequency (00:07:20) Exercise, Zone 2 Cardio; Caloric Restriction (00:08:36) Intermittent Fasting, Growth Hormone, IGF-1 (00:11:05) Hormones & Sleep, Growth Hormone, Menopause, Andropause, TRT (00:13:28) Testosterone & Women, SHGB (00:15:19) Sponsor: Maui Nui (00:16:34) Dihydrotestosterone (DHT), Androgens; Turmeric & Black Pepper; Hair Loss (00:19:47) Polycystic Ovarian Syndrome (PCOS), Symptoms, Metformin, Inositol (00:23:13) Cannabis, Alcohol, Testosterone (00:24:48) Males & Testosterone, TRT, Prostate Cancer (00:26:04) Prolactin, Dopamine "Wave Pool", Tool: Casein & Gluten (00:27:23) Sponsor: Function (00:29:03) Social Relationships & Hormones, Tool: Planning for Crisis (00:31:02) Peptides, Growth Hormone & Risk; BPC 157, Sourcing & LPS (00:36:42) Melanotan, Uses & Risks (00:38:45) Spiritual Health, Interdisciplinary Health Integration (00:41:23) Caffeine & Hormones, Sleep; Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode covers: • Nano CBD Pain Relief Without Cognitive Side Effects A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support. Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm • Moderate Calorie Restriction Slows Biological Aging A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting. Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults • FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer's The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer's disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair. Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/ • Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.” Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged) • Klotho: The Longevity Protein Nears Clinical Reality The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols. Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged) All source links provided for easy reference to the original reporting and research above. This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host Dave Asprey and the latest breakthroughs shaping the future of health. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer's microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:19 — Story 1: Nano CBD for Pain Relief 1:53 — Story 2: Caloric Restriction and Aging 3:20 — Story 3: AI Robotic Surgery for Alzheimer's 4:50 — Story 4: Microbiome Reprogramming 6:05 — Substack Announcement 7:04 — Story 5: Klotho Longevity Protein 8:39 — Weekly Homework 9:31 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.
Join Cynthia Thurlow for another insightful episode of what we like to call “She Said, She Said,” where she teams up to tackle your most pressing health and wellness questions. Dive into real conversations about navigating perimenopause while raising kids, evolving perspectives on fasting, and whether dairy is truly a friend to your gut. Discover the latest on cold plunges for women, strength training routines, and the safest approach to caloric restriction. This episode also explores the science behind peptides, microdosing GLP-1s, and the best forms of testosterone therapy for women. Whether you're on a wellness journey or just curious, this episode delivers trusted advice, expert tips, and empowering insights you won't want to miss.Episode Overview (timsestamps are aproximate):(0:00) Intro/Teaser(5:00) Midlife Parenting (Perimenopause with Kids)(17:00) Muscle Building in Menopausal Women(27:00) Long-Term Effects of Caloric Restriction(34:00) Challenges & Strategies for “Reverse Dieting”(40:00) Dairy & Gut Health in Women(48:00) Hormesis & Testosterone Options for Women(1:01:00) Personalized Health & Fitness Strategies(1:12:00) Microdosing Peptides for Health Benefits(1:17:00) Medication & Body Composition MonitoringResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep440/We couldn't do it without our sponsors:TIMELINE - As perimenopausal women, we know we are in a fight against time to preserve our muscle strength and endurance, plus our recovery needs are greater. That's why you save 20% at https://timelinenutrition.com/better with code BETTER.PIQUE - Designed to deeply hydrate, enhance skin elasticity & firmness and support sustained energy. Start your daily ritual today with 20% off for life—plus a free gift to elevate your routine. Head to https://piquelife.com/drestima.ONESKIN - Harness the power of peptides for fuller hair and glowing skin. Save 15% at https://oneskin.co/better with code BETTER.EQUIP COLLAGEN - Support bones, joints, gut, and skin with Equip Collagen. Get 20% off at https://equipfoods.com/better with code BETTER.LVLUP - Ultimate GI Repair combines powerful gut-healing peptides with gut-nourishing naturals to soothe your changing digestion. Go to https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
On this week's Flex Diet Podcast, I sit down with Angelo Keely, co-founder of Kion, to geek out on all things essential amino acids (EAAs). We'll dig into the nitty-gritty science and—more importantly—what that means for you in the real world.Want to pack on more muscle? Drop some fat without feeling wrecked? Stay strong and sharp as the years tick by? EAAs can help—if you know how to use them. We'll break down why they're not just “protein lite,” how they work differently than your standard whey shake, and the smartest ways to add them into your nutrition strategy.If you care about muscle, performance, or aging like a badass, this one's worth a listen.Sponsors:Kion EAAs: https://www.getkion.com/collections/drmikeAvailable now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:01:30 – Meeting Angelo Keely at ISSN 03:00 – Essential Amino Acids: What Are They? 06:00 – Protein vs. EAAs vs. BCAAs 09:30 – The Science of Protein Synthesis 13:00 – Muscle Gain, Body Composition, and Aging 17:00 – EAAs for Fat Loss and Caloric Restriction 21:00 – Research on EAAs and Muscle Preservation 25:00 – Supplement Quality: What to Look For 28:00 – How to Use EAAs: Dosing and Timing 32:00 – EAAs for Older Adults and Special Populations 36:00 – Taste, Formulation, and Product Differences 40:00 – Practical Tips for Athletes and Everyday Use 44:00 – Creatine vs. EAAs: Which to Choose? 47:00 – Real-World Experiences and Anecdotes 50:00 – Q&A and Final Thoughts Episode 291: Anabolic Strategies and Nutrition Tips to Maximize Muscle Growth & Health with Dr David ChurchFlex Diet Podcast Episodes You May Enjoy: Episode 291: Anabolic Strategies and Nutrition Tips to Maximize Muscle Growth & Health with Dr David Church YouTube: https://youtu.be/VudpMeB_33w Episode 274: How Muscle Fibers Influence Metabolism: Insights from Nathan SerranoYouTube: https://youtu.be/Ul2TOiodgaoConnect with Angelo:Instagram: https://www.instagram.com/angelokeelyKion: https://www.getkion.comWebsite: https://www.angelokeely.com/Get In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us
Weight loss isn't always just about “calories in, calories out.” And on today's show, I'm sharing research that reveals why how you eat can be just as important—if not more—than how much you eat. I'll break down a clinical study comparing a 4:3 intermittent fasting plan to traditional daily calorie restriction and reveal which approach came out on top. If you're curious whether intermittent fasting can boost both weight loss and overall health—and want to know which wins in the battle of intermittent fasting vs. daily calorie restriction—join me on today's Cabral Concept 3470 to discover the winning strategy. - - - For Everything Mentioned In Today's Show: StephenCabral.com/3470 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Weight loss isn't always just about “calories in, calories out.” And on today's show, I'm sharing research that reveals why how you eat can be just as important—if not more—than how much you eat. I'll break down a clinical study comparing a 4:3 intermittent fasting plan to traditional daily calorie restriction and reveal which approach came out on top. If you're curious whether intermittent fasting can boost both weight loss and overall health—and want to know which wins in the battle of intermittent fasting vs. daily calorie restriction—join me on today's Cabral Concept 3470 to discover the winning strategy. - - - For Everything Mentioned In Today's Show: StephenCabral.com/3470 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
The dark personality traits that underlie online political engagement; Parents' use of topical hormone preparations may pose unusual risks to their babies; Alternative to beta blockers for high blood pressure; Does lecithin lower cholesterol? Caloric restriction may extend life—but at what cost? A high-fiber diet may mimic caloric restriction's longevity benefits; Can mammograms cause cancer?
In this deeply informative solosode, Dr. Mike Belkowski guides listeners through a comprehensive exploration of mitochondrial function and its profound connection to aging and longevity. Kicking off with a brief reflection on recent guest episodes and a teaser about an upcoming podcast rebrand, Mike then dives into a newly released scientific article from Cell Communication and Signaling titled “Mitochondrial Dysfunction in the Regulation of Aging and Aging-Related Diseases.” Mike reads and unpacks dense but crucial sections from the paper, including: The Structure and Function of MitochondriaHe outlines the intricacies of the electron transport chain, supercomplexes, and mitochondrial DNA, emphasizing their roles in energy production, oxidative stress, and aging. Key Cellular Processes Affected by MitochondriaTopics covered include metabolic regulation, calcium and ROS homeostasis, mitochondrial biogenesis, and autophagy, tying them all back to aging and degenerative diseases. Modulating Mitochondrial Function to Slow AgingMike highlights emerging research on mitochondrial nutrients (like CoQ10, alpha-lipoic acid, carnitine), lifestyle interventions (exercise, diet, intermittent fasting), and breakthrough therapies such as mitochondrial transfer and replacement therapies. He also introduces BioLight's new supplement, BioBlue Fountain of Youth, emphasizing its inclusion of methylene blue or leucomethylene blue, urolithin A, adaptogenic mushrooms, shilajit, and PQQ—all aimed at mitochondrial optimization. The episode wraps with a powerful message: movement is medicine. Exercise remains the most accessible and potent strategy to boost mitochondrial health naturally. Mike encourages listeners to stay active, get sunlight, engage in red light therapy, and embrace the mitochondrial lifestyle. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key Quotes from Dr. Mike Belkowski: “The mitochondrial space is going to be blown up in the next couple decades for sure… it's going to become a much larger, well-adopted aspect of health and wellness.” “You don't want these dysfunctional cells or these dysfunctional mitochondria to linger around… you want them to be recycled and turned into new, healthy cells.”“Exercise is the best way to have your endogenous program of mitogenesis running.” - Key points: 00:00 – Introduction: Mitochondrial Focus and Podcast Evolution 02:14 – Podcast Rebrand Announcement & Mitochondrial Mission 03:15 – Review of Article: Mitochondrial Dysfunction in Aging 04:09 – Structure of the Mitochondria: A Deep Dive 06:15 – Electron Transport Chain & Supercomplexes Explained 10:05 – Mitochondrial DNA, Genome, and Gene Expression 11:18 – New BioBlue Supplement Overview and Key Ingredients 14:01 – Mitochondrial Functions: Metabolism, Apoptosis, and Energy 16:29 – Calcium Homeostasis & ROS Generation 20:11 – Antioxidant Defense Systems in Mitochondria 22:15 – Overview of Remaining Sections in the Research Article 25:18 – Targeting Mitochondria to Slow Aging: Introduction 27:13 – Nutrients That Modulate Mitochondrial Function 29:29 – Hormetic Stress, Resilience, and Mitochondrial Biogenesis 31:22 – Calcium Modulators and Mitochondrial Stability 32:01 – Exercise as the Ultimate Mitochondrial Booster 35:03 – Exercise vs. Caloric Restriction in Mitochondrial Health 36:30 – Mitochondria-Supportive Diets and Nutrients 39:12 – Mitochondrial Therapy and Replacement Explained 42:18 – Mitochondrial Replacement for Age-Related Decline 44:17 – Cross-Tissue Mitochondrial Signaling in Aging 45:41 – Translational Research in Mitochondrial Therapeutics 49:08 – Future of Mitochondrial Medicine and Final Thoughts - Save 25% when you Subscribe & Save to a BioBundle!For a BioBundle, you choose: 1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement (Regular or Concentrated) The BioBundle automatically saves you 15% on both of the supplements you choose. You save an additional 10% by choosing to Subscribe & Save to that BioBundle. The 25% savings is passed along for every monthly delivery of your BioBundle. No discount code necessary! Discount automatically applied at checkout. Shop BioBundle by clicking here! - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram Facebook
BUFFALO, NY — June 24, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 5, on May 20, 2025, titled “Short-term moderate caloric restriction in the rhesus macaque attenuates markers of ovarian aging in select populations.” In this study, led by first author Emma S. Gargus and corresponding author Francesca E. Duncan from Feinberg School of Medicine at Northwestern University, researchers explored how dietary changes impact ovarian aging in female rhesus macaques. They found that a three-year moderate reduction in caloric intake preserved a youthful distribution of ovarian follicles and reduced age-related tissue stiffness. These findings are relevant to women's health as they suggest that caloric restriction (CR) may help delay the decline in reproductive function associated with aging. Ovarian aging, which leads to reduced fertility and hormone production, is one of the earliest signs of aging in women. This study investigated whether a 30% reduction in caloric intake could protect the ovaries from age-related damage in nonhuman primates (NHP), whose reproductive biology closely mirrors that of humans. Ovaries were collected from young (10–13 years) and old (19–26 years) rhesus macaques who were either on a diet of moderate caloric restriction or a control diet for three years. “To test the effect of CR on follicle number, follicles were analyzed in histological sections from animals across experimental cohorts: Young Control, Young CR, Old Control, Old CR (n = 4–8/group).” Although total follicle numbers still declined with age, caloric restriction helped maintain the types of follicles most associated with reproductive potential. In older monkeys who were still cycling, even if irregularly, caloric restriction preserved more primordial follicles, the key indicators of ovarian reserve, than in those on a normal diet. The benefits of caloric restriction were also seen in the structure of ovarian tissue. Normally, aging leads to fibrosis, a stiffening of the ovarian environment caused by increased collagen and decreased hyaluronic acid. This study showed that caloric restriction reduced this fibrotic process, suggesting a more supportive environment for maintaining reproductive health. While the diet did not stop the overall loss of follicles with age, it improved the proportion of younger, more viable follicles in aging ovaries. The timing of the dietary intervention also appeared to matter. Positive effects were more noticeable in older animals with irregular cycles than in those who had completely stopped cycling. This indicates that starting caloric restriction at a certain point in the reproductive lifespan may yield the best results. This research is an important step to identifying lifestyle-based strategies that can extend reproductive longevity. Although further studies are needed to test these findings in humans, the work supports the potential of moderate dietary changes to delay ovarian aging and help preserve fertility later in life. DOI - https://doi.org/10.18632/aging.206253 Corresponding author - Francesca E. Duncan - f-duncan@northwestern.edu Video short - https://www.youtube.com/watch?v=AvgZR3X3nyU Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206253 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
In this episode, we sit down with Dr. Matthew Dawson, the founder and CEO of Wild Health, and leader in genomics-based precision medicine. Dr. Matt breaks down what precision medicine truly means--how it goes beyond traditional healthcare to create highly personalized plans based on your unique genetic blueprint and blood work. We explore some of the most important genes to assess for optimizing health, performance, and longevity, including the ApoE gene. He shares powerful insights into the future of medicine and why understanding your genetics is crucial for extending healthspan. Plus, we open up about our own personal Wild Health test results and how they've shaped our individual wellness journey. This conversation is packed with actionable insights you won't want to miss!Dr. Matthew Dawson is the founder and CEO of Wild Health, a genomics-based precision medicine company, and the CEO of TruDiagnostic, an epigenetics testing lab. He has authored two textbooks, published over two dozen studies, lectured in over 20 countries, and won national awards for education and innovation. His passion is unlocking the secrets of the genome and epigenome and using them to optimize health and maximize healthspan. He lives in the woods with his wife, four children, and two dogs.SHOW NOTES: 0:31 Welcome to the show!3:57 Dr. Matt Dawson's Bio4:40 Welcome Dr. Matt to the show!5:14 What is “Precision Medicine”?7:14 Your genes are not your destiny11:09 Renee's experience with Bulletproof coffee11:38 MTHFR & Homocysteine12:43 Combining lab work with genetics17:24 Alzheimer's genetics20:32 What to do for APOE-3/422:56 Biomarkers for optimal health 24:28 Can you change your sleep chronotype?28:26 Genes for telomere length31:37 *ALIGN MAT*33:16 *PIQUE TEA*35:27 Boosting BDNF37:30 Something new about HbA1C!39:47 FOXO3 Gene for Longevity43:40 Blue Zones & social connection45:12 Testing Biological Age49:08 Caloric Restriction for Longevity51:42 The perfect diet for your genes53:25 Comparing macro tolerances57:37 Wild Health reports 59:12 Coming soon for Precision Medicine!1:04:16 His final piece of advice1:04:56 Thanks for tuning in!RESOURCES:Website: wildhealth.com - discount code: BIOHACKERBABESInstagram: wildhealthmdLinkedIn: Wild HealthMy Align Mat - discount code: BIOHACKERBABES to save $250Pique Tea - Save $ with this link!Puori - Save 20% with discount code: BIOHACKERBABESEffecty - Save $50 with discount code: BIOHACKERBABESOur Sponsors:* Check out Effecty and use my code BIOHACKERBABES for a great deal: https://www.effecty.com* Check out Puori: https://Puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Biohacking for Longevity: Extending Your Health Span. In this episode of "Leyla Weighs In," registered dietician and nutritionist Leyla Muedin discusses the concept of biohacking and its potential to extend lifespan and health span. Leyla explores various biohacking strategies such as diet optimization, regular physical activity, stress management, enhancing sleep quality, and maintaining strong social connections. She emphasizes the importance of epigenetics, targeted lifestyle changes, and advanced medical interventions like stem cell therapy. You will learn practical biohacking tips, including the benefits of intermittent fasting, the significance of exercise, and how to use wearable technology for health tracking. Leyla also highlights the role of supplements and personalized nutrition in promoting longevity, alongside maintaining good dental health and a sense of purpose. Through these combined efforts, Leyla aims to inspire listeners to not only live longer lives but to enjoy better health and vitality.
Want to live longer and feel better? Dr. G breaks down the top 5 science-backed strategies to increase longevity and boost your health. From strength training to cardiovascular fitness, social connections, and better sleep, this is your ultimate guide to aging well. Plus, learn about key supplements that can support your journey! #health #antiaging #wellness ==== Thank You To Our Sponsors! Timeline Visit https://timelinenutrition.com/drg and use code DRG to get 10% off BiOptimizers Go to https://bioptimizers.com/drg and use promo code DRG10 to get 10% any order. ==== Timestamps: 00:00:00 - Introduction: The Importance of Muscle Mass and Longevity 00:01:00 - The Five Evidence-Based Ways to Extend Your Life 00:02:33 - #5: Strength Training for Longevity 00:09:36 - #4: Sleep Quality and Duration 00:11:36 - #3: Caloric Restriction and Fasting 00:15:14 - #2: Social Connection and Purpose 00:18:26 - #1: Cardiovascular Fitness 00:20:14 - Conclusion: Taking Control of Your Longevity
What does true health look like? In this episode, I sit down with Justin Nault, health coach and founder of Clovis, to break down the biggest myths in nutrition and fitness while sharing practical steps to transform your health.We discuss why reproductive ability is a key marker of health, how caloric restriction isn't the answer, and why community and personal growth play a bigger role in well-being than you might think. Justin also shares insights on fasting for metabolic health, the dangers of seed oils, and why prioritizing protein intake is crucial for optimal wellness.Plus, Justin opens up about his personal journey, including the impact of his niece Savannah's health struggles and his own experiences with dry fasting and plant medicines. Whether you're looking to optimize your hormonal health, metabolism, or overall well-being, this episode is packed with science-backed insights and actionable advice you can implement today!What We Cover in This Episode:
On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Caloric restriction and its effects on lifespan are explored through an evolutionary lens.Michael highlights the challenges and breakthroughs in longevity research. He touches upon the role of genetics and pharmaceuticals in manipulating lifespan and healthspan. He points to the Pacific rockfish as an example of varying lifespans within a closely related group of species, demonstrating the genetic component of aging. He also notes the impact of Cell reprogramming, referencing a study on how specific Cell reprogramming can regenerate optic nerves.The conversation shifts to the business of longevity, where Michael discusses the increased interest and investments from big pharma and billionaires. He examines the economic benefits of extending healthspan, citing a potential value of $300 trillion from a 10-year healthspan extension in the US alone. Michael and Gil also explore the importance of lifestyle choices for healthy aging, emphasizing diet, exercise, sleep, stress management, and social connections.Guest-at-a-Glance
Discover the five essential factors that contribute to a long, healthy life. From the power of community to caloric restriction, deep sleep, sunlight, and core strength, this episode uncovers research-backed strategies to enhance your longevity. Learn how small daily changes can lead to a vibrant, fulfilling life at 100 and beyond! 5 KEY TAKEAWAYS Community is key: Strong social connections and a sense of belonging are crucial for longevity. Caloric restriction boosts lifespan: Eating less without malnutrition activates longevity pathways like autophagy. Quality sleep detoxifies the brain: Deep sleep promotes growth hormone production and clears harmful waste. Daily sunlight resets your body clock: Proper exposure to natural light optimizes circadian rhythms and overall health. Core strength predicts longevity: The ability to get up from the floor without assistance is linked to a longer life. FEATURED PRODUCT: Mitochondriac Mitochondriac is packed with resveratrol, a powerful antioxidant that mimics the effects of caloric restriction and promotes mitochondrial biogenesis. This essential supplement supports cellular energy, fights oxidative stress, and enhances overall longevity—perfect for those looking to live to 100! TIMESTAMPS 00:00 START 02:15 The first secret: The power of community 10:40 How genetics influence only 20% of lifespan 15:30 What we can learn from centenarians and Blue Zones 21:50 The second secret: Caloric restriction for longevity 30:15 How fasting triggers autophagy and mitochondrial health 38:10 The third secret: Why sleep is crucial for living to 100 RESOURCES MENTIONED "How to Live to 100" – Research on longevity and centenarians https://www.today.com/health/aging/how-to-live-to-100-rcna104086 "Life Advice from Centenarians" – AARP insights on aging well https://www.aarp.org/health/healthy-living/info-2023/life-advice-from-centenarians.html "Live Healthy to 100" – OSU study on aging factors https://alumnimagazine.osu.edu/story/live-healthy-100 "Caloric Restriction and Longevity" – NIH research on fasting https://pmc.ncbi.nlm.nih.gov/articles/PMC9036399/ "The Okinawan Secret to Longevity" – Blue Zones research https://www.bluezones.com/2020/07/why-the-okinawan-practice-of-sitting-on-the-floor-is-linked-to-health-mobility-and-longevity-how-you-can-practice-it-at-home/
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Subscribe to our channel: https://www.youtube.com/@optispan In this episode with our guest Dr. Thomas Seager, we delve into the transformative power of cold plunge therapy and its profound effects on resilience and longevity. We explore real-life case studies, including lessons learned from infrastructure failures like Hurricane Katrina and the Oroville Dam crisis. Discover how psychological resilience shapes our responses to stress, the importance of hormesis in health, and the role of brown fat in metabolism. We also discuss the impact of fasting, caloric restriction, and the relationship between mitochondrial health and aging. 00:00 - Introduction to Cold Plunge and Resilience 03:33 - Types of Stress & Responses 14:18 - Mitochondrial Health, Caloric Restriction & Metabolism 23:05 - Cold Therapy and Brown Fat 54:10 - Conclusions & Final Thoughts Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcast Twitter: https://twitter.com/optispan Twitter: https://twitter.com/mkaeberlein Linkedin: https://www.linkedin.com/company/optispan Instagram: https://www.instagram.com/optispanpodcast/ TikTok: https://www.tiktok.com/@optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden interviews Hannah Went, co-founder of TrueAge, a leading omics age company. They discuss the significance of epigenetics in understanding biological age, the predictive power of various aging clocks, and the advancements in measuring biological age through multi-omics approaches. The conversation also covers the impact of interventions like caloric restriction on aging metrics, the Dunedin Pace as a new metric for biological aging, and the complexity of aging as a multifactorial process. Went shares insights into the future of epigenetic research and the importance of actionable insights for health optimization. For the audience: * Use the code 'Podcast10' to get 10% OFF your order at our supplement store → https://gladdenlongevityshop.com/ Takeaways * Epigenetic markers can predict chronological age with high accuracy. * GrimAge is a new clock that estimates mortality risk. * Multi-omics approaches provide a comprehensive view of aging. * Caloric restriction significantly impacts biological age. * Dunedin Pace measures the rate of biological aging. * Aging is a complex, multifactorial process. * Understanding what tests do not measure is crucial. * New biomarkers for aging are being developed and validated. Chapters 00:00 Introduction to Omics Age and TrueAge 04:12 The Evolution of Epigenetic Clocks 07:55 Integrating Lifestyle Factors in Omics Age Testing 10:14 Predicting Disease Risk and Mortality with Omics Age 13:27 Reversing Biological Age with Interventions 16:42 Actionable Insights from Omics Age Testing 26:30 Exploring the Impact of Caloric Restriction on Aging 29:08 Understanding the Dunedin Pace as a Measure of Biological Aging 33:32 The Complexity of Aging and the Limitations of Single Metrics 35:24 Epigenetic Biomarker Proxies: A Comprehensive Approach to Aging 43:59 Cell Reprogramming and its Implications for Aging 49:24 Goodbye Learn more about TruAge and/or contact them: Email: hannah@trudiagnostic.com Website: https://www.trudiagnostic.com/ Facebook: https://www.facebook.com/TruDiagnostic/ Instagram: https://www.instagram.com/trudiagnosticofficial/ X: https://x.com/TruDiagnostic YouTube: https://www.youtube.com/c/trudiagnostic TikTok: https://www.tiktok.com/@trudiagnostic?is_from_webapp=1&sender_device=pc LinkedIn: https://www.linkedin.com/company/trudiagnostic/ Reach out to us! Website: https://gladdenlongevity.com/ Email: podcast@gladdenlongevity.com Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw
LAST DAY TO SAVE! TONE COLLAGEN is NOW OUT! Check it out HERE & get 15% OFF for the LAUNCH with the code KG15! Hi friends! This episode is about New Studies: Pre-Workout Carbs vs Fasted Workouts, Autophagy & Fat Loss - Fasting VS Caloric Restriction, Can Women Gain Muscle & Strength as Much As Men & More! See the study HERE Jump to the start of studies at 27:05 Get 20% off the Tone LUX Crystal Red Light Therapy Face Mask with the code VANESSA Get 20% off Energybits with the code KETOGIRL HERE Everyone is loving Tone Protein! Scientifically formulated based on the science to support Muscle Protein Synthesis. Click Here to Check it out! Join the Community! Follow Vanessa on instagram to see her meals, recipes, informative posts and much more! Click here @ketogenicgirl Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the facebook group for the podcast: https://www.facebook.com/groups/2017506024952802/ Thank you to our sponsor: Bioptimizers Magnesium Breakthrough is one of the only supplements I take with me when I travel as it is so important to me! Save 10% OFF with the code VANESSA at bioptimizers.com/vanessa - This podcast content does not constitute an attempt to practice medicine and does not establish a doctor-patient relationship. Please consult a qualified healthcare provider for medical advice and personal health questions. Prior to beginning a new diet you should undergo a health screening with your physician to confirm that a new diet is suitable for you and to out any conditions and contraindications that may pose risks or are incompatible with a new diet, including by way of example: conditions affecting the kidneys, liver or pancreas; muscular dystrophy; pregnancy; breast-feeding; being underweight; eating disorders; any health condition that requires a special diet [other conditions or contraindications]; hypoglycemia; or type 1 diabetes. A new diet may or may not be appropriate if you have type 2 diabetes, so you must consult with your physician if you have this condition. Anyone under the age of 18 should consult with their physician and their parents or legal guardian before beginning such a diet. Use of Ketogenic Girl podcasts & videos are subject to the Ketogenicgirl.com Terms of Use and Medical Disclaimer. All rights reserved. If you do not agree with these terms, do not listen to, or view any Ketogenic Girl podcasts or videos.
Why do drugs like Ozempic work? In this episode of Piloting Health, Dr. Frank Dos Santos joins me once again for an in-depth look at the most talked-about drugs on the market right now: GLP-1 agonists.We break down exactly why the drugs cause weight loss, but also how that weight loss can lead to a reduced change of certain types of diseases. What is it about caloric restriction that can help stave off disease? In this vein, we also talk intermittent fasting and I even espouse my theory that the body encourages fasting when combatting certain types of cancer. It goes without saying that any decision to begin any type of drug or medical regiment needs to be discussed with your physician, so we're not advocating for any individual to begin GLP-1 agonists or fasting but, in general, the results we're seeing from caloric restriction seem to be very positive in many circumstances. In this episode, Dr. Dos Santos and I break down exactly why.To follow Dr. Dos Santos, you can find him on Instagram:@drfrankdossantosFollow Dr. Bob Hariri on his platforms here:Web: www.pilotinghealth.comInstagram: https://www.instagram.com/drbobhariri/X: https://twitter.com/DrBobHaririTikTok: https://www.tiktok.com/@pilotinghealthLinkedIn: https://www.linkedin.com/in/drbobhariri/
Send us a textIn this fascinating episode, I sit down with Victor Sagalovsky, co-founder and CEO of Lightwater Scientific, a trailblazer in the world of deuterium depletion and its transformative impact on human health. Victor's passion for understanding the quantum biology of water has led him to pioneer a revolutionary approach to longevity, energy optimization, and overall vitality through deuterium-depleted water. During our conversation, Victor dives into the science behind deuterium depletion and how it enhances mitochondrial function, oxygen utilization, and even helps to slow the aging process. He shares insights into the intricate relationship between water, energy production at the cellular level, and how managing deuterium levels can unlock profound benefits for performance, recovery, and longevity. This episode is a must-listen for anyone curious about the cutting-edge intersection of water science, quantum biology, and longevity. Whether you're a biohacker, health enthusiast, or just seeking to elevate your wellness journey, Victor's expertise offers a unique and powerful perspective on how to use deuterium-depleted water as a tool for optimized health and performance. Tune in to discover how to take your health to the next level with insights that are both deeply scientific and highly actionable.Key Points From This Episode:00:04:24 - Introduction to Victor and Lightwater Scientific00:05:10 - Understanding Deuterium Depleted Water (DDW)00:06:42 - The Science Behind Energy Production00:12:33 - The Impact of Deuterium on Aging00:22:02 - The Process of Creating DDW00:35:36 - Caloric Restriction and Deuterium00:49:10 - Future Possibilities with Deuterium Management01:00:24 - Discovering the Self Through Water01:22:03 - Understanding Water's Role in Mineralization01:36:01 - Setting a Baseline for Deuterium Levels!Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today's Episode:Click HERE to save on BiOptimizers MagnesiumSpecial Offer:Get 10% off your first order with the discount code: PHYSIO.Also receive 20% off your Deuterium Tests.PeopleVictor SagalovskyLinkedIn ProfileDr. Laszlo BorosOfficial WebsiteDr. Gerald PollackOfficial WebsiteDr. Jack KruseOfficial WebsitePlacesLightwater ScientificOfficial WebsiteWater SymposiumWater Symposium Official WebsiteBooks and References"The Fourth Phase of Water" by Dr. Gerald PollackBook on AmazonDeuterium Test KitDeuterium Test WebsiteSupport the show
In this conversation, Kayla Barnes and JJ Virgin discuss women's health, fitness, and aging. They debunk myths about women and weightlifting, emphasize the importance of strength training, and highlight the need to focus on the basics of health and fitness. They also discuss the impact of hormones on women's health, particularly during perimenopause and menopause. The conversation emphasizes the importance of managing stress, optimizing thyroid function, and working with a knowledgeable healthcare provider to address hormonal changes. In this conversation, Kayla Barnes discusses various topics related to women's health, including hormone replacement therapy (HRT), weight loss, bone health, and exercise. She emphasizes the importance of getting a DEXA scan to assess bone mineral density and body composition. Barnes also highlights the benefits of resistance training, high-intensity interval training (HIIT), and power training for women. She recommends incorporating creatine supplementation and tracking total body water to monitor muscle health. Overall, Barnes encourages women to prioritize their health and make informed choices to optimize their well-being. Certified Nutrition Specialist Board Certified In Holistic Nutrition®Certified Personal Trainer About JJ As a triple-board certified nutrition expert and Fitness Hall of Famer, JJ is a passionate advocate of nutrition's healing power and is mission driven to ignite a movement of women choosing to age powerfully. After decades of watching women strive to shrink themselves, JJ is urging women to step into their power—physically and personally. Using her principles of powerful aging, she inspires women to get strong, get bold, and get what they want in life. She embodies her philosophy as both a legendary personal trainer and the founder of 2 multimillion-dollar businesses: her personal brand and the Mindshare Collaborative, the most influential professional community in health, having propelled more New York Times bestsellers, PBS specials, and 7 figure brands than any other community. Chapters 00:00 Introduction and Debunking Myths About Women and Weightlifting 08:10 The Importance of Strength Training for Women 19:20 Managing Hormonal Changes During Perimenopause and Menopause 27:05 The Role of Stress Management and Thyroid Function in Women's Health 33:29 Noticing Changes and the Importance of Hormones 36:50 Aging Powerfully and Embracing Personal Choices 37:19 Supporting Women and Avoiding Judgment 37:50 Hormone Replacement Therapy and Weight Loss 38:46 Factors Affecting Weight Loss and Body Composition 39:45 Starting with a Diet Audit and Tracking 41:14 Optimizing Protein Intake and Adding Nutrients 43:09 Caloric Restriction and Cycling 45:58 Protein Shaming and Prioritizing Protein 50:42 Exercising for Bone Health and Muscle Strength 52:58 Tracking Steps and Incorporating Bodyweight Exercises 56:21 Workout Options When Limited on Equipment 58:13 Training Frequency and Adjusting Based on Feel 01:02:31 Assessing Bone Health with DEXA Scans 01:03:26 The Benefits of Creatine Supplementation
Despite your best efforts to diet & shift your lifestyle, are you still lacking the results you hoped for? You may be unknowingly sabotaging yourself. This episode challenges common myths about keto, intermittent fasting, and caloric restriction, highlighting the critical role of metabolic flexibility & the stress impacts of certain diets. Discover the transformative effects of techniques like Buteyko breathing & CO2 therapy, & learn how your individual genetics and lifestyle choices shape your health. Meet our guest Jay is a health coach, independent health researcher, & the host of The Energy Balance Podcast. He has degrees in neuroscience & exercise physiology, & decided to forgo medical school after realizing that the conventional medical approach was not the solution to the health problems that so many of us face. After working through various conventional & alternative health paradigms & trialing countless diets, Jay came across the idea that cellular energy is the foundation of our health. Embracing this discovery, he now uses the Energy Balance approach to help men & women around the world maximize their cellular energy, optimize their health, & achieve freedom from low-energy symptoms & chronic health issues. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan Key takeaways The idea that fat burns cleaner than glucose is a misconception; in many cases, glucose burns more efficiently Short-term, ketones can boost metabolism, but long-term reliance on them can lower metabolic rates and promote fat storage Ketones are primarily used by the brain; the rest of the body relies on fat The brain, with its high metabolic needs, relies on glucose or ketones rather than fatty acids due to their more efficient energy production Carbon dioxide (CO2) has antioxidant effects, helping protect against reactive oxygen and nitrogen species, and is beneficial in low-oxygen states Chronic stress reduces CO2 levels, which can impact health Episode Highlights 11:17 Everything You Need to Know About Balancing Stress & Energy 20:16 The Truth About Caloric Restriction & Fasting 34:14 Fats VS Carbs (The Ultimatum) 42:26 Controversial Health Practices for Longevity 47:47 Surprising Health Benefits of CO2 & Oxygen Links Watch it on YouTube: https://youtu.be/14i898-9DCY Full episode show notes: mindbodypeak.com/172 Connect with Nick on social media Instagram Twitter YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick
In today's episode, we explore common mistakes that can hinder your intermittent fasting success. Tune in to hear the common pitfalls I see all the time that can sabotage your fat loss and make you gain weight instead. Learn about simple but crucial changes to boost your metabolism and address insulin sensitivity issues. We'll discuss research on meal timing and its impact on your body's natural rhythms, and I'll share insights on optimizing eating schedules for better health outcomes. One major pitfall we'll address is how you approach your feeding windows. We'll delve into the importance of balanced eating and avoiding extreme behaviors that can sabotage your efforts. Discover strategies for maximizing the benefits of intermittent fasting, including its effects on cellular processes and hormone regulation. I'll also reveal my personal approach to managing hunger and maintaining muscle mass during fasting periods. Another crucial aspect we cover is the role of nutrition and hydration in your fasting routine. Learn why the quality of your food choices matters and how proper hydration can impact your results. I'll offer practical tips for staying on track and explain why consistency in your fasting schedule is essential for long-term success. Finally, we'll discuss the importance of micronutrients and how to ensure you meet your body's needs. Join me as we uncover these essential insights and actionable tips to make your intermittent fasting journey successful and sustainable! FULL show notes: https://www.jjvirgin.com/fastingmistakes 7-Day Eat Protein First Challenge: http://jjvirgin.com/proteinfirst Reignite Wellness™ Magnesium Body Calm: https://reignitewellness.com/products/magnesium-body-calm Download my free Resistance Training Cheat Sheet: https://jjvirgin.com/resistance Sugar Impact Diet: https://reignitewellness.com/products/sugar-impact-diet-paperback-book Study: Beneficial Effects of Early Time-Restricted Feeding on Metabolic Diseases: Importance of Aligning Food Habits with the Circadian Clock: https://www.mdpi.com/2072-6643/13/5/1405 Study: Health Benefits of Fasting and Caloric Restriction: https://link.springer.com/article/10.1007/s11892-017-0951-7 Study: Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21-month-old rats: a mitochondria-mediated pathway: https://pubmed.ncbi.nlm.nih.gov/17142793/ Study: Brain–Gut–Microbiome Interactions and Intermittent Fasting in Obesity: https://ncbi.nlm.nih.gov/pmc/articles/PMC7916460/ Study: 10-Hour Eating Window Boosts Mood and Energy: https://neurosciencenews.com/intermittent-fasting-mood-25207/ Study: Assessment of water consumption during Ramadan intermittent fasting: Result from Indonesian cross-sectional study: https://pubmed.ncbi.nlm.nih.gov/35958263/ Study: Intermittent fasting 5:2 diet: What is the macronutrient and micronutrient intake and composition?: https://pubmed.ncbi.nlm.nih.gov/32199696/ Episode Sponsors: Try Timeline: https://www.timelinenutrition.com/shop?rfsn=7082975.4b75243 Use code JJ10 for 10% off all products Go to qualialife.com/VIRGINWELLNESS to try Qualia risk-free for up to 100 days and code VIRGINWELLNESS for an additional 15% off
In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive. We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan. Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk. Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter's Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor 01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter's Supplements 02:18:46 Andrew's Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy 02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
Episode Highlights With Hannah WentWhat biological age is and how we measure itUnderstanding cellular-based aging How we measure biological ageSprint speed and grip strength can be really loose indicators of biological ageUnderstanding epigenetic biomarker proxies and how to pull levers to improve your biological ageHow biological age is closely tied to all-cause mortality The biggest factors that affect biological age negatively or positively Not surprisingly, smoking and alcohol consumption are negative factors for biological ageDiet, physical activity, sleep, and stress make a big impact on biological ageHow caloric restriction comes into play for aging Pregnancy and menopause effects on aging Epigenetic transgenerational inheritance and how this affects our kidsHow sunlight affects biological age (and it might not be what you think)Spending time in green space and in nature has a positive effect on biological age and even IQBeing lonely is worse than smoking according to research from HarvardHow relationships and community improve biological ageResources We MentionTruDiagnostic (this link and code wellnessmama gives a discount)Hand Grip Strength Tester
Free newsletter and more: https://newsletter.sankalpgarud.org/52waysguide In this episode of the Understanding Emotions, we explore the crucial pillars of health—sleep, exercise, and nutrition—while diving into the ethical and scientific dimensions of biohacking and longevity. Dr Sanchit Turuga is a medical doctor at the UK's National Health Service and a DPhil (PhD) student in medicine at the University of Oxford. 00:00 Introduction and Setting the Stage 01:25 Foundations of Good Health 03:34 Challenges in Maintaining Health 06:10 The Importance of Sleep 18:53 Exercise: The Second Pillar of Health 32:59 The Impact of Diet on Health 33:39 Debating the Benefits of Vegetarianism 35:05 The Need for More Research 35:57 Practical Challenges of Changing Diets 37:10 Concluding Thoughts on Nutrition 38:34 The Role of Supplements in Health 45:06 The Common Cold and Immunity 51:18 The Debate on Health Tracking and Measurement 01:00:33 The Concept of Longevity Clinics 01:08:05 The Parabiosis Experiment and Blood Transfusions 01:10:28 Biohacking and Longevity Optimization 01:12:21 Caloric Restriction and Exercise for Longevity 01:15:31 The Debate on Aging as a Disease 01:18:15 Personalized Medicine and Supplementation 01:29:28 Gut Microbiome: The New Frontier 01:38:11 Personalized Medicine and Alternative Therapies 01:43:13 Conclusion and Final Thoughts
Join Dr. Josh Axe as he interviews Dr. Paul Saladino, a double board-certified MD and founder of Heart & Soil, who challenges conventional wisdom about diet and chronic illness. In this eye-opening episode, these two experts dive deep into controversial topics that could revolutionize your approach to health. They discuss: How modern medicine often fails to address the root causes of chronic diseases The surprising environmental impact of veganism vs. carnivore diets Do carnivores eat fruit and vegetables? How to develop a growth mindset and challenge your own beliefs about nutrition Recommendations for reversing autoimmune disease Tune in to gain invaluable insights that could transform your understanding of optimal health. Whether you're a nutrition enthusiast or simply looking to improve your well-being, this episode will equip you with cutting-edge knowledge to make informed decisions about your diet and lifestyle. Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. Follow Dr. Josh Axe Instagram Twitter Facebook Tik-Tok Follow Dr. Paul Saladino Instagram Twitter YouTube Tik-Tok ------ 0:00 Dr. Paul Saladino Background 9:01 Are vegetables REALLY good for you 16:45 Yin Vs. Yang Diet 24:28 Incorporating Organ Meats in Diet 30:32 Supplements & Vitamins 35:50 Environmental Impacts of Vegan Vs. Carnivore Diet 46:11 Should We Be Eating Fruit? 58:35 Why Most Studies Are False 1:02:54 Caloric Restriction & Fasting 1:10:56 Is Cold Plunging Good For You? 1:14:20 How to Deal With Criticism ------ Links: Check out the Paul Saladino MD Podcast → https://www.paulsaladinomd.co/resources/podcasts Purchase Dr. Paul Saladino's book, The Carnivore Code Book → https://www.paulsaladinomd.co/resource/the-carnivore-code Check out Dr. Paul Saladino's grass-fed beef and organ meat sticks → https://lineageprovisions.com/
Amping AMP-activated protein kinase is one of the anti-aging pathways I cover in my longevity book, How Not to Age.
This week's episode of The Flex Diet Podcast is a special co-broadcast with Dr. Lonnie Lowery and Iron Radio. We come to you live from the annual International Society of Sports Nutrition conference. From the surprising revelation that creatine is illegal for individuals under 18 in New York, shared by Guillermo Escalante, to the debunking of common misconceptions about creatine, this episode is packed with the latest information on dietary science. We discuss the potential benefits of creatine for kids and pregnant women and emphasize the importance of accurate safety data and validating study materials. We also shed light on the prevalent issue of low energy availability among athletes, exploring the balance between dietary intake and metabolic rate. Tune in for this and much more!Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%Episode Chapters:(0:00:00) - Sports Nutrition Conference Highlights and Insights(0:07:28) - Effects of GLP-1 Agonists on Appetite(0:13:55) - Nootropics and Anabolism in Nutrition(0:20:11) - Sleep, Diet, & Muscle Anabolism Effects(0:30:14) - Sleep Science Advancements and Data Analysis"(0:41:43) - Creatine Research Findings and Applications(0:46:32) - Creatine Loading and Probiotic Research(1:00:19) - Enhanced Physiques and Deuterated Caffeine(1:06:20) - Elite Masters Athletes and Research Findings(1:11:19) - Nutrition Challenges for Older AthletesFlex Diet and Iron Radio Podcast Episodes You May Enjoy:Flex Diet Podcast Episode 239: Exploring the Science Behind Dieting Strategies with Dr. Bill CampbellIron Radio: Creatine and Sleep, Botanicals, Developing GritIron Radio Episodes:Youtube: https://www.youtube.com/@Lonman07Get In Touch:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/
In this episode, CJ delves into the science and practical aspects of caloric restriction, an effective approach to extending lifespan and improving health. Caloric restriction involves reducing calorie intake without causing malnutrition, which has been shown to reduce age-related diseases and improve metabolic health. Key Points Discussed:Introduction to Caloric RestrictionExplanation of caloric restriction and its benefits.Overview of scientific research supporting its efficacy in extending lifespan and enhancing health.Science Behind Caloric RestrictionReduces oxidative stress by lowering the production of free radicals.Enhances cellular repair mechanisms through processes like autophagy.Promotes healthier cells and improved overall health and longevity.Practical Tips for Incorporating Caloric RestrictionIntermittent Fasting: Popular method like the 16/8 approach (16 hours fasting, 8 hours eating).Reducing Daily Calorie Intake: Aim for a 10-20% reduction, focusing on nutrient-dense foods.Mindful Eating: Pay attention to hunger and fullness cues, eat slowly, and savor your meals.Meal Planning: Plan meals ahead to ensure a balance of nutrients and avoid impulsive eating.Monitoring Progress: Keep track of calorie intake and overall well-being using food diaries or apps.Benefits of Caloric Restriction Beyond LongevityImproved metabolic health.Reduced risk of age-related diseases.Enhanced overall well-being.ConclusionEncouragement to make thoughtful dietary choices for long-term health.Reminder to consult healthcare providers before making significant dietary changes.Key Takeaways:Caloric restriction can significantly enhance your lifespan and health by reducing oxidative stress and promoting cellular repair.Intermittent fasting and mindful eating are effective strategies for reducing calorie intake.Planning meals and monitoring progress are crucial for maintaining nutritional balance and achieving caloric restriction goals.The approach is not about deprivation but making healthier, more thoughtful dietary choices.5 Things You Can Start Doing Today:Try Intermittent Fasting: Start with the 16/8 method to control your eating window and reduce calorie intake.Reduce Your Caloric Intake: Aim for a moderate reduction of 10-20% in your daily calories.Eat Nutrient-Dense Foods: Focus on fruits, vegetables, lean proteins, and whole grains to get essential nutrients without excess calories.Practice Mindful Eating: Slow down during meals, pay attention to your body's signals, and stop eating when you feel satisfied.Plan Your Meals: Prepare balanced meals in advance to avoid impulsive eating and ensure you meet your nutritional needs.Caloric restriction is a sustainable and scientifically backed approach to improving health and extending lifespan. By incorporating these practices into your daily routine, you can support your body's natural repair processes and achieve a healthier, longer life. Always consult with a healthcare provider before making significant changes to your diet.
Join us as we welcome Dr. Stephen Noseworthy to discuss the principles of functional medicine. Dr. Noseworthy shares his personal journey from marketing professional to a pioneer in alternative health, emphasizing the importance of understanding individual biological differences and metabolic adaptability. He provides practical advice on tailoring health strategies, covering topics such as fasting, exercise, and caloric management based on his extensive clinical experience.Explore the shift from traditional to modern, technology-driven medical consultations, highlighting the balance between family life and a successful virtual clinic. We delve into the enhancements in patient engagement and care efficacy brought by innovations like social media and electronic medical records, drawing on the economic challenges and adaptability required in the early days of establishing a functional medicine practice.Concluding our episode, Dr. Noseworthy addresses complex health issues like autoimmunity and neurological conditions, debunking common health myths and urging personalized treatment plans. He discusses the importance of dietary customization, particularly the balance of caloric intake for optimal brain function, and challenges popular misconceptions with a clinical approach that respects individual health profiles. Chapters:(00:00) Functional Medicine with Dr. Noseworthy(11:10) Evolution of a Virtual Practice(15:54) Transitioning to Virtual Practice and Technology(25:47) Exploring Autoimmunity and Functional Medicine(40:00) Impact of Caloric Restriction on Brain(46:30) Carbohydrate Sweet Spot and Energy Sufficiency(55:41) Clinical Approach to Functional Medicine Links:Drnoseworthy.comInflammation Nation Podcast (https://podcasts.apple.com/us/podcast/inflammation-nation-science-informed-wellness/id1587867271)Func Med Nation Podcast (https://podcasts.apple.com/us/podcast/func-med-nation-a-podcast-for-functional/id1669044741) Join Over 18,000 Leading Medical Professionals and Become a Vibrant Wellness Provider Today! (https://portal.vibrant-wellness.com/#/sign-up)
// GUEST // Podcast: https://podcasts.apple.com/us/podcast/paul-saladino-md-podcast/id1461771083 The Carnivore Code: https://www.amazon.com/dp/B089KB41VCThe Carnivore Code Cookbook: https://www.amazon.com/dp/B08NWTKQLF Website: https://www.paulsaladinomd.co/ YouTube: https://www.youtube.com/@Paulsaladinomd Twitter: https://twitter.com/paulsaladinomd Instagram: https://www.instagram.com/paulsaladinomd/ TikTok: https://www.tiktok.com/@paulsaladinomd2// SPONSORS // In Wolf's Clothing: https://wolfnyc.com/Heart and Soil Supplements (use discount code BREEDLOVE): https://heartandsoil.co/Anthony DiClementi's Biohacking Secrets (Text BREEDLOVE to 847-943-7221) Swan Bitcoin: https://www.swanbitcoin.com/breedlove22/// EVENTS I WILL BE ATTENDING // Bitcoin 2024: the World's Largest Bitcoin Conference (use discount code BREEDLOVE): https://b.tc/conferenceLibertarian National Convention: https://lnc2024.com/ Pacific Bitcoin 2024: https://www.pacificbitcoin.com/// PRODUCTS I ENDORSE // Protect your mobile phone from SIM swap attacks: https://www.efani.com/breedlove// OUTLINE // 0:00 - WiM Show Intro 1:57 - Helping Lightning Startups with In Wolf's Clothing 2:45 - Introducing Paul Saladino 8:49 - What is an Animal-Based Diet? 17:01 - Paul's Daily Diet 26:38 - Restricting Carbohydrates 32:26 - Heart and Soil Supplements 33:26 - Anthony DiClementi's Biohacking Secrets 34:55 - Animal-Based Travel Tips 42:26 - Dangers of Seed Oils 53:48 - Calories In vs Calories Out 01:04:15 - Diet vs Exercise 01:06:54 - Swan Bitcoin: Set up instant and Recurring Bitcoin Buys 01:08:27 - Bitcoin 2024: The Largest Bitcoin and Fintech Conference in the World 01:09:33 - Bryan Johnson's Blueprint 01:20:58 - Risks of Fasting 01:32:37 - Caloric Restriction 01:37:11 - Quality vs Quantity 01:40:17 - Where to find Paul Saladino// PODCAST // Podcast Website: https://whatismoneypodcast.com/Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?RSS Feed: https://feeds.simplecast.com/MLdpYXYI// SUPPORT THIS CHANNEL // Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7 Sats via Strike: https://strike.me/breedlove22 Sats via Tippin.me: https://tippin.me/@Breedlove22Dollars via Paypal: https://www.paypal.com/paypalme/RBreedloveDollars via Venmo: https://account.venmo.com/u/Robert-Breedlove-2The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101 // WRITTEN WORK // Medium: https://breedlove22.medium.com/Substack: https://breedlove22.substack.com/ // SOCIAL // Breedlove Twitter: https://twitter.com/Breedlove22WiM? Twitter: https://twitter.com/WhatisMoneyShowLinkedin: https://www.linkedin.com/in/breedlove22/Instagram: https://www.instagram.com/breedlove_22/TikTok: https://www.tiktok.com/@breedlove22All My Current Work: https://vida.page/breedlove22
This episode is brought to you by Cozy Earth, Lifeforce, and Lumebox.Despite significant strides in cancer research over the past two decades, there remains a vast realm of uncertainty surrounding the impact of various cancers on individuals. Amidst the proliferation of cancer discourse on social media, distinguishing evidence-based information from conjecture can prove challenging. Today's guest is here to untangle all the complexities. Today, on The Dhru Purohit Show, Dhru sits down with Dr. Joseph Zundell to discuss the research behind cancer prevention. Dr. Zundell shares the lifestyle factors that influence the development of cancer and the cutting-edge technologies for early cancer detection. Dr. Joe Zundell received his Ph.D. in cancer biology through the University of the Sciences and The Wistar Institute in Philadelphia, PA. He has over ten years of cancer research experience as a cancer biologist. Much of his published research has focused on finding new therapies for the treatment of many different cancer types based on the epigenetic and metabolic characteristics of cancers. In this episode, Dhru and Dr. Zundell dive into (audio version / Apple Subscriber version):Technology for early detection of cancer (4:55 / 4:55)Obesity and visceral fats link to cancer (22:56 /19:30)Exercising to build muscle and for longevity (28:57 / 25:06)Protein intake and the metabolic process (35:00 / 30:23)Fasting mimicking diet before chemotherapy (47:14 / 42:17)Otto Werberg's research (53:17 / 49:39)Cancer as a metabolic disease (58:15 / 53:40)An overview of Dr. Thomas Seyfried's work and Dr. Zundell's viewpoint (1:07:07 / 1:02:08)Dr. Zundell's views on what needs additional research (1:09:43 / 1:05:09)Dr. Zundell's origin story (1:18:54 / 1:13:00)Socioeconomic status and its impact on disease (1:30:37/ 1:26:38)Rapid fire community questions (1:34:02 / 1:28:35)Also mentioned in this episode:Dr. Zundell's research Get $300 off Prenuvo at prenuvo.com/dhru (not an affiliate link)Ezra Test Fasting and Caloric Restriction in Cancer Prevention and TreatmentProfessor Valter Longo's Study Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DHRUP.Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress go to mylifeforce.com/dhru! Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 50% off! Go to thelumebox.com/dhru and get your Red Light device. Hosted on Acast. See acast.com/privacy for more information.
How can we make sense of the disparate results from the four primate studies on caloric restriction and lifespan?
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We are aware of the benefits of both intermittent fasting and caloric restriction when it comes to weight loss and health. But what happens when we combine these two approaches? A recent study claims to be the first to explore this combination, and today I will discuss the findings and provide my insights. Tune in to today's #CabralConcept 2812 to learn about combining intermittent fasting and caloric restriction and how you can incorporate that into your diet. Enjoy the show and let me know what you thought! - - - For Everything Mentioned In Today's Show: StephenCabral.com/2812 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
In this journal club episode, my guest is Stanford and Johns Hopkins-trained physician, Dr. Peter Attia, M.D., who is also the host of The Drive podcast and the author of the bestselling book "Outlive: The Science & Art of Longevity." We each present a scientific paper and discuss the findings' strengths, weaknesses and actionable takeaways. First, we discuss an article that addresses whether taking the drug metformin can enhance longevity. Then, we discuss an article on belief effects (similar to placebo effects), showing how the effects of a drug on the brain and cognition depend on one's belief about the dose of the drug taken, not the actual dose. Our conversation also highlights how to read, interpret and critique scientific studies. This episode ought to be of interest to those curious about health and longevity, medicine and psychology and for anyone seeking to better understand how to read and digest scientific findings. For the full show notes, including articles, books, and other resources, visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix Sleep: https://helixsleep.com/huberman Levels: https://levels.link/huberman InsideTracker: https://insidetracker.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Dr. Peter Attia, Journal Club 00:03:27 Sponsors: Helix Sleep & Levels 00:06:11 Dreams 00:12:36 Article #1, Metformin, Mitochondria, Blood Glucose 00:19:47 Type 2 Diabetes & Causes, Insulin Resistance 00:25:30 Type 2 Diabetes Medications, Metformin, Geroprotection, Bannister Study 00:36:19 Sponsor: AG1 00:37:15 TAME Trial; Demographics, Twin Cohort 00:44:27 Metformin & Mortality Rate 00:51:28 Kaplan-Meier Mortality Curve, Error Bars & Significance, Statistical Power 01:01:17 Sponsor: InsideTracker 01:02:23 Hazard Ratios, Censoring 01:09:00 Metformin Advantage?, Variables, Interventions Testing Program 01:16:02 Berberine, Acarbose, SGLT2 Inhibitors 01:23:48 Blood Glucose & Energy Balance; Caloric Restriction, Aging Biomarkers 01:32:22 Tool: Reading Journal Articles, 4 Questions, Supplemental Information 01:38:10 Article #2, Belief Effects vs. Placebo Effect 01:45:22 Nicotine Effects 01:51:07 Nicotine Doses & Belief Effects, fMRI Scan 02:00:07 Biological Effects, Dose-Dependent Response & Belief Effects 02:05:14 Biology & Beliefs, Significance, Dopamine Response, Non-Smokers 02:10:57 Dose-Dependence & Beliefs, Side Effects, Nocebo Effect 02:19:06 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer
Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! Learn how to RAMP UP into longer fasting windows! Gain insights into the non-weight loss benefits of fasting! Personalize your own fasting schedule and consistent FAT LOSS results! Get answers to what breaks a fast, how to break a fast, and tips and tricks to accelerate your fasting wins! THE BLUEPRINT TO FASTING FOR FAT LOSS DOWNLOAD In today's episode, Dr. Scott and Tommy explore how fasting has transformed their lives and share actionable steps. They review a study comparing intermittent fasting plus early time-restricted eating with calorie restriction for at-risk individuals. The importance of consistent fasting strategies, even small decisions adding up over time, and much more. Show Transcript: www.thefastingforlife.com/blog Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! Fasting For Life Community - Join HERE New to the podcast and wondering where to start? Head to the website and download our Fast Start Guide, 6 simple steps to put One Meal a Day Fasting (OMAD) into practice! Get our NEW sleep guide here! SLEEP GUIDE DIRECT DOWNLOAD If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them Article Links: https://www.mdpi.com/2079-7737/12/3/372# https://pubmed.ncbi.nlm.nih.gov/34389873/ https://www.health.harvard.edu/heart-health/what-is-heart-rate-variability https://www.whoop.com/thelocker/whoop-proven-most-accurate-wearable-in-heart-rate-heart-rate-variability-measurements/ https://pubmed.ncbi.nlm.nih.gov/31558032/ https://pubmed.ncbi.nlm.nih.gov/26277879/
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