Podcasts about sll

We recorded a thicc episode for you this month with our special guest Sarah, one of the hosts of the podcast Afternoona Asks! Together, we get into the nitty-gritty of red flag and green flag characters and cover a lot of ground: from what makes a red flag red and a green flag green, to the surprising gender dynamics of “flagging” characters at all.Along the way, we mention a lot of our favorite love interests, including Baek Seon of When the Phone Rings, Mr. Gu of My Liberation Notes, Captain Ri of gateway KDrama Crash Landing on You, and many, many more. (If you want an SLL drinking game, take a sip every time Ayanni says "interesting"

It's time for our annual SLL tradition of rounding up the pop culture of the previous year! We start with what pop-culture is "sparking joy” in February,  our favorites of 2024, and what we're looking forward to in 2025.As a treat, Corinne's snark levels were very high this episode (lol).CW: Brief mention of S*icide from (1:06:51-1:06:54)Show Notes: Take the SLL Audience Survey! Closes March 28th, 2025: https://forms.gle/AJhFuMDzjSZeTE1f8 Support us on Ko-Fi: https://ko-fi.com/sexlovelitpodcast Check out Corinne's 2024 drama round ups on Tumblr: Korean Dramas: https://www.tumblr.com/starcrossed591/770716418956312576/kdrama-year-in-review-2024?source=share Chinese Dramas: https://www.tumblr.com/starcrossed591/771029764525916160/cdrama-year-in-review-2024?source=share Lit Mentioned By Section: What's Sparking Joy Feb 2025: The Spellshop by Sarah Beth Durst, Half a Soul by Olivia Atwater, and My Old Ass Joy Sparked in 2024 - Yoga with Kassandra (https://www.youtube.com/user/yogawithkassandra), Long Live Evil by Sarah Rees Brennan, My Sweet Mobster (KDrama), As If Love Does Not Exist (Webtoon), Blossom (CDrama), Kaos, True Detective (Season 4), Someone to Build a Nest In by John Wiswell, Poor Things, Challengers, Build Mama a Coffin: An Old Gods of Appalachia story (https://www.oldgodsofappalachia.com/episodes/2020-02-06/build-mama-a-coffin-trailer/202002061153231909) Joy Sparked in 2024, Deep Dives - Lovely Runner (KDrama),The Princess Royal (CDrama), Look Back, Flow, Nosferatu (2024) Future Joy Sparked in 2025: Back After This by Linda Holmes, Wheel of Time (Season 3), Witch Hat Atelier anime, Sinners Others: Extraordinary You, Goblin, Romance of Tiger and Rose, Love Like the Galaxy, Flourished Peony, Abbott Elementary, Blue Box, My Happy Marriage, Apothecary Diaries, Toilet Bound Hanako-Kun, Perfect Marriage Revenge, Marry My Husband, The Wild Robot Check out SLL Live in 2025: April 2025 - Romance in CNY: ⁠⁠⁠⁠⁠⁠https://romanceincny.com/⁠⁠⁠⁠⁠⁠ July 2025 - RomantiConn: ⁠⁠⁠⁠⁠https://www.romanticonn.com/⁠⁠⁠⁠⁠On Future SLL Episodes: Strangers Again, Let's Get Divorced, and Trope Spotlight: Forced Proximity.Don't forget to subscribe to Sex. Love. Literature! You can find us at ⁠⁠⁠⁠⁠⁠⁠⁠SexLoveLitPodcast.com⁠⁠⁠⁠⁠⁠⁠⁠; on Instagram , Tumblr, and BlueSky @SexLoveLitPodcast. Support us on Ko-fi: https://ko-fi.com/sexlovelitpodcast⁠Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr;Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US.Sex. Love. Literature. is a pop culture podcast that relishes the romantic, the sexy, and the scandalous in media. Join pop culture scholars (and besties) Ayanni and Corinne as they deep dive into why the “sex-stuff” in media matters. Main episodes drop the last Friday of the month.

Featuring perspectives from Dr Jennifer Woyach, including the following topics: AMPLIFY — First-Line Trials Combining Bruton Tyrosine Kinase (BTK) Inhibitors with Venetoclax Introduction (0:00) Case: An African American man in his mid 40s with progressive lymphadenopathy in the neck is diagnosed with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) with trisomy 12 and an SF3B1 mutation — Erik Rupard, MD (1:50) Pirtobrutinib Questions for the Faculty: Effectiveness and tolerability of pirtobrutinib for patients with CLL and disease progression on prior BTK inhibition — Zanetta S Lamar, MD (21:18) Choice of First-Line BTK Inhibitor Case: A woman in her mid 80s diagnosed with CLL more than 30 years ago now has relapsed/refractory, ibrutinib-intolerant disease — Warren S Brenner, MD (31:29) Cardiotoxicity of BTK Inhibitors  Case: A man in his early 70s with chronic atrial fibrillation requiring long-term anticoagulation is diagnosed with IGHV-unmutated CLL with del(13q), del(17p) and an XPO1 mutation — Bhavana (Tina) Bhatnagar, DO (34:53) Case: A man in his mid 70s with trisomy 12, IGHV-unmutated CLL has a history of congestive heart failure (ejection fraction 20% to 25%) resulting in multiple hospital admissions — Laurie Matt-Amaral, MD, MPH (37:51) CLL and COVID-19 Vaccinations; Role of MRD Testing; Anti-CD20 Antibodies Case: A man in his early 60s with CLL receives first-line obinutuzumab/venetoclax and has a moderate infusion reaction to obinutuzumab — Dr Rupard (41:17) Case: A man in his early 60s with CLL and well controlled autoimmune hemolytic anemia on ibrutinib is switched to zanubrutinib — Dr Lamar (45:26) Questions for the Faculty: CLL and COVID-19 vaccinations; role of MRD testing; anti-CD20 antibodies — Dr Brenner (49:23) Case: An Amish man in his mid 60s requires treatment for CLL but is paying for treatment “out of pocket” — Dr Rupard (55:33) CME information and select publications  

Featuring perspectives from Dr Nicole Lamanna, including the following topics: Introduction (0:00) Case: A man in his late 60s with IGHV-mutated chronic lymphocytic leukemia (CLL) (trisomy 12) and progressive adenopathy — Bhavana (Tina) Bhatnagar, DO (1:22) Case: A woman in her mid 70s with IGHV-unmutated, del(13q) CLL and fatigue — Erik Rupard, MD (19:57) Case: A woman in her mid 80s with del(13q) CLL under watchful waiting develops progressive symptoms — Shams Bufalino, MD (30:00) Case: A woman in her early 60s diagnosed with small lymphocytic leukemia (SLL) now with disease progression on ibrutinib — Warren S Brenner, MD (33:08) Current role of pirtobrutinib; CAR T-cell therapy; Richter's transformation — Dr Brenner (36:04) Case: A man in his mid 40s with SLL who received second-line venetoclax/rituximab — Yanjun Ma, MD (50:01) CME information and select publications

In this episode, listen to Matthew S. Davids, MD, MMSc​, and Lindsey Roeker, MD, discuss BTK inhibitor resistance and how it shapes treatment choices for patients with CLL, including:Contemporary treatment paradigms for patients with CLLSafety and efficacy of current regimensMolecular testing, including when and how to test for BTK inhibitor resistanceConsidering BTK inhibitor resistance when sequencing therapy Program faculty:Matthew S. Davids, MD, MMSc​Associate Professor of Medicine​Harvard Medical School​Leader, Lymphoma Program​Dana-Farber/Harvard Cancer Center​Director of Clinical Research​Division of Lymphoma​Dana-Farber Cancer Institute​Boston, Massachusetts​​Lindsey Roeker, MD​Assistant Attending​CLL Program Director​Department of Medicine​Memorial Sloan Kettering Cancer Center​New York, New YorkResources:To review a CME-certified text activity and download slides associated with this podcast discussion, please visit the program page.

In classic SLL fashion, I welcome you to another accidental two-part discussion. This time, we're joined by Dr. Kai Chen to discuss Malinda Lo's award-winning novel, Last Night at the Telegraph Club. This episode, we keep things spoiler free by first giving some context for the book and then our overall impressions. (Plus, we get a bonus visit from Ayanni's 20 year old family cat.) Show Notes: What's Sparking Joy: Kevin can F*** Himself (on Netflix), Mayonaka Punch (on Crunchyroll), Are You The One (on Viki), and Delicious in Dungeon (on Netflix) Other lit discussed this episode: Goodbye My Princess, Evangelion, Ashe (by Malinda Lo), My Favorite Thing is Monsters Learn more about Dr. Chen's work on the UF University Writing Program website: https://writing.ufl.edu/directory/yukai-chen/ Support your local bookstore and Malinda Lo by getting Last Night the Telegraph Club on Bookshop.org: https://bookshop.org/p/books/last-night-at-the-telegraph-club-malinda-lo/16520139?ean=9780525555278 Learn more Pen America and their various initiatives: https://pen.org/ Check out SLL Live in 2025: April 2025 - Romance in CNY: ⁠https://romanceincny.com/⁠ July 2025 - RomantiConn: https://www.romanticonn.com/ On Future SLL Episodes: Strangers Again, Let's Get Divorced, Trope Spotlight: Forced Proximity, and A Court of Thorns and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us at ⁠⁠⁠SexLoveLitPodcast.com⁠⁠⁠; on Instagram and on Tumblr @SexLoveLitPodcast. Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). TheSLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr;Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US Sex. Love. Literature. is a pop culture podcast that relishes the romantic, the sexy, and the scandalous in media. Join pop culture scholars (and besties) Ayanni and Corinne as they deep dive into why the “sex-stuff” in media matters. Main episodes drop the last Friday of the month.

W tym tygodniu wracamy do tematu Sustainabilty-Linked oraz ESG-Linked financing - ale w ujęciu praktycznym. Gościem odcinka jest Jadwiga Pisarska,  Ekspertka ds. ESG i Zrównoważonego Finansowania w Banku BNP Paribas, która podzieli się swoimi doświadczeniami zawodowymi oraz badawczymi z transakcjami tego rodzaju.  Tematem rozmowy będą m.in. przykłady transakcji SLL z kraju i stosowane w nich wskaźniki ESG. Poznamy również skalę tego nurtu zrównoważonego finansowania i zastanowimy się nad miejscem tych rozwiązań w "zielonych finansach" ogólnie. Nie zabraknie też pytań o przyszłość i największe wyzwania dla tego rynku.  Zapraszamy! 

During the European Hematology Association (EHA) 2024 Hybrid Congress, the Lymphoma Hub was pleased to speak to Paolo Ghia, Vita-Salute San Raffaele, Milan, IT. We asked about the latest update on the SEQUOIA trial of zanubrutinib + venetoclax in treatment-naïve patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Hosted on Acast. See acast.com/privacy for more information.

Due to circumstances entirely within our control, we interrupt your regularly scheduled SLL programming for a special summer edition of our What's Sparking Joy: Pop Culture Round Up.  In addition to checking in about what we've been watching, reading, and listening to so far this year, we each share three pieces of media that continue to live rent free in our heads. Lit Discussed this Episode: Lost You Forever Season 2 (no spoilers), Challengers, There's a Door in this Darkness, A Sign of Affection, The Princess Royal, The Bear, and The Midnight Romance in Hagwon Content Warning: Familial de*th is mentioned twice in this episode, at (26:12) and again at (48:40) Show Notes: Come visit Ayanni at the SLL table during RomantiConn this July! The vendors room is free to visit: ⁠⁠⁠https://www.eventbrite.com/e/romanticonn-2024-a-romance-author-signing-event-tickets-786820470207⁠⁠⁠ ; https://www.facebook.com/groups/351611412074474/ Other Lit Mentioned this Episode: Love Between Fairy and Devil; Crash Landing on You; My Dearest; Red, White and Royal Blue; The Legend of Shen Li; Wedding Impossible; Captivating the King; Bitterblue; Silent; Romance is a Bonus Book; One Spring Night; Something in the Rain; Crash Course in Romance On Future SLL Episodes: Strangers Again, Let's Get Divorced, Last Night at the Telegraph Club, Trope Spotlight: Forced Proximity, and A Court of Thorns and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us at SexLoveLitPodcast.com; on Instagram and Threads @SexLoveLit; and on Tumblr @SexLoveLitPodcast Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠⁠⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US Sex. Love. Literature. is a pop culture podcast that relishes the romantic, the sexy, and the scandalous in media. Join pop culture scholars (and besties) Ayanni and Corinne as they deep dive into why the “sex-stuff” in media matters. Main episodes drop the last Friday of the month.

CME credits: 0.50 Valid until: 23-07-2025 Claim your CME credit at https://reachmd.com/programs/cme/chairperson-perspective-practice-changing-strategies-in-community-care-settings-for-patients-with-cllsll-and-mcl/18098/ Although covalent Bruton's tyrosine kinase (BTK) inhibitors have proven to be effective in treating chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) or mantle cell lymphoma (MCL), patients still experience poor outcomes after treatment failure or intolerance, necessitating new therapeutic options. Next-generation non-covalent, reversible BTK inhibitors, which have increased specificity and a novel mechanism of action, may address unmet needs and deliver better care. These next-generation BTK inhibitors have been successful in clinical trials and are changing the treatment paradigm as well as practice guidelines. Understanding key differences between the covalent and non-covalent BTK inhibitors, along with recent clinical trial data, will allow the clinical care team to introduce and integrate newly approved practice-altering therapies into current treatment plans to best meet the needs of their diverse patients with CLL/SLL or MCL. In this educational activity, the expert faculty Chairperson will review the latest clinical evidence supporting the efficacy, safety, and tolerability of reversible, non-covalent BTK inhibitors to enhance incorporation into evidence-driven treatment sequencing for patients with CLL/SLL and MCL. The Chairperson will present a summary of the most relevant and timely advances with non-covalent BTK inhibitors while layering in their own personal, expert perspectives on how community care teams can …=

Welcome to our second episode on Bridgerton, season three! Picking up where we left off, we jump right into close reading Polin's main sex scenes. From there, we think about what made us adore the side plots through discussion of Benedict, Francesca, and Violet's storylines this season.  Note: there are Bridgerton book spoilers from (37:36 - 38:14) and again from (39:27 - 39:47). Make sure to listen to part one of our season three discussion- E44 Bridgerton, Season 3: "I need some f*replay, okay?!" (Episode 1 of 2): https://podcasters.spotify.com/pod/show/sexlovelit/episodes/E44-Bridgerton--Season-3-I-need-some-freplay--okay---Episode-1-of-2-e2ldc1t/a-abd482b Show Notes: Come visit Ayanni at the SLL table during RomantiConn this July: ⁠⁠https://www.eventbrite.com/e/romanticonn-2024-a-romance-author-signing-event-tickets-786820470207⁠⁠ Hear Corinne repping for SLL over on the VoxPopCast: ⁠https://voxpopcast.com/wp/2024/06/24/e324-unpacking-bridgerton-season-3-penelope-queerness-and-fandom-reactions/⁠ Other Lit Mentioned this episode: What's Sparking Joy: "Black Dog" by Taylor Swift, "Do 2 Me" by Kaytranada feat Anderson .Paak and SiR On Future SLL Episodes: Strangers Again, Let's Get Divorced, Last Night at the Telegraph Club, and A Court of Thorns and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us on Instagram and Threads @SexLoveLit, and on Tumblr @SexLoveLitPodcast Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US Sex. Love. Literature. is a pop culture podcast that relishes the romantic, the sexy, and the scandalous in media. Join pop culture scholars (and besties) Ayanni and Corinne as they deep dive into why the “sex-stuff” in media matters. Main episodes drop the last Friday of the month.

Members of the ton rejoice! Both halves of Bridgerton, season three have finally dropped. We had so many thoughts about this latest installment of the regency romance series that–just like Netflix–we split our conversation in two. In this first episode, we consider the season as a whole, break down Pen and Colin's long awaited transition from friends to lovers, and start to craft "Bridgerton, Season Three: the Corinne and Ayanni Cut." The second part of our conversation drops on Saturday, June 29th. Show Notes: Come visit Ayanni at the SLL table during RomantiConn this July: ⁠https://www.eventbrite.com/e/romanticonn-2024-a-romance-author-signing-event-tickets-786820470207⁠ Hear Corinne repping for SLL over on the VoxPopCast: https://voxpopcast.com/wp/2024/06/24/e324-unpacking-bridgerton-season-3-penelope-queerness-and-fandom-reactions/ Other Lit Mentioned this episode: What's Sparking Joy: Last Night at the Telegraph Club and Meet Yourself (Chinese Drama) Because This is My First Life, My Liberation Notes, Pop Culture Happy Hour On Future SLL Episodes: Strangers Again, Let's Get Divorced, Last Night at the Telegraph Club, and A Court of Thorns and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us on Instagram and Threads @SexLoveLit, and on Tumblr @SexLoveLitPodcast Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US Sex. Love. Literature. is a pop culture podcast that relishes the romantic, the sexy, and the scandalous in media. Join pop culture scholars (and besties) Ayanni and Corinne as they deep dive into why the “sex-stuff” in media matters. Main episodes drop the last Friday of the month.

Obszar zrównoważonego finansowania można oceniać nie tylko z perspektywy inwestorów/akcjonariuszy, ale również ze strony kredytodawców. W tej domenie coraz prężniej zaczynają działać banki oferujące tzw. kredyty SLL (Sustainability Linked Loans), a więc taki rodzaj finansowania na preferencyjnych warunkach cenowych, który ma być przed kredytobiorcę spożytkowany na cele związane ze zrównoważonym rozwojem. Przykładem wykorzystywania takich narzędzi jest chociażby finansowanie budowy energooszczędnych mieszkań czy wymiana floty samochodowej firm na hybrydową lub elektryczną. Od strony instytucji finansowych z kolei upowszechnienie takiej formy finansowania wymaga wzmacniania kompetencji analitycznych oraz ujednolicenia kryteriów w branży. O właściwościach, wyzwaniach i rozwoju rynku kredytów SLL opowiada Joanna Sobótka-Klimczak, Sustainability Expert w ING Banku Śląskim. Zapraszamy!

Time for the third installment of our divorce comedy mini-series! While we didn't initially plan to include this show, we're talking about the recently concluded Korean drama Queen of Tears. We consider whether or not the show is actually a divorce comedy at all, how it deploys divorce in the development of the main relationship, and what about this second chance romance really resonates. We also touch on some of the other things that did–and didn't–work for us in the drama as a whole. Content warning: Because of the nature of the show we're discussing, there are mentions of fictional s*icide at 9:50, 11:41, and 40:44; discussion of a fictional miscarriage starting at 43:20; and discussion of fictional terminal illness throughout. Show Notes: Come visit Ayanni at the SLL table during RomantiConn this July: https://www.eventbrite.com/e/romanticonn-2024-a-romance-author-signing-event-tickets-786820470207 Read Corinne's Tumblr post on Drama Recs for KDrama Beginners: https://www.tumblr.com/sexlovelitpodcast/747784569802080256/sex-love-lit-girlies-i-watched-crash-landing-on?source=share Other Lit Mentioned this episode: Dungeon Meshi (Delicious in Dungeon), Twenty Sided Tavern, Baulder's Gate, Dungeons and Dragons, The Guy She's Interested in isn't a Guy at All; Lovely Runner, Crash Landing on You, Cinderella and the Four Knights, My Love From Another Star, Legend of the Deep Blue Sea, Gaus Electronics, Let's Talk About Chu, Mine, Little Women, Vincenzo, The Interest of Love On Future SLL Episodes: Strangers Again, Let's Get Divorced, and A Court of Thorns and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us on Instagram and Threads @SexLoveLit, and on Tumblr @SexLoveLitPodcast Our cover art is by Charcooll (⁠⁠⁠⁠⁠⁠https://www.instagram.com/charcooll/⁠⁠⁠⁠⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US SLL is a podcast relishing the romantic, the sexy, and the scandalous in pop-culture. English academics by day and podcasters by night, hosts Ayanni and Corinne take a semi-scholarly look at why the “sex-stuff” in media matters in the bedroom—and beyond.

Fernando Pérez Pacho nos habla hoy del 'Love Bombing' o Bombardeo Amoroso. Se trata de un intento de influir en una persona mediante demostraciones de atención y afecto. Se puede utilizar de diferentes formas y con fines positivos o negativos. Los psicólogos han identificado el bombardeo amoroso como una posible parte de un ciclo de abuso y han advertido contra él. También se ha descrito como manipulación psicológica para crear un sentimiento de unidad dentro de un grupo contra una sociedad percibida como hostil.  Hagamos un poco de historia. En 2011, el psicólogo clínico Oliver James defendió el bombardeo de amor en su libro Love Bombing: Reset Your Child's Emotional Thermostat, como un medio para que los padres rectifiquen los problemas emocionales de sus hijos.Las redes sociales modernas pueden intensificar el efecto del bombardeo amoroso, ya que le dan al abusador un contacto y una comunicación casi constantes con la víctima. Una de las señales del bombardeo amoroso en el inicio de una relación es la atención intensa durante un corto período de tiempo y la presión por un compromiso muy rápido. El psicólogo Dale Archer identifica las fases del bombardeo amoroso con el acrónimo IDD: "Intensa idealización, devaluación, descarte (repetición)" y el proceso de identificación de este patrón de comportamiento como SLL: "Stop, Look, and Listen"; después de lo cual romper el contacto con el abusador puede ser más posible buscando también el apoyo de familiares y amigos. Otra señal de bombardeo amoroso es la lluvia intensa de cariño, regalos y promesas de futuro con el depredador para que la víctima sienta o se le haga creer que todo esto es una señal de “amor a primera vista”. Dado que tales muestras de afecto y afirmación pueden satisfacer las necesidades sentidas y no parecer dañinas en la superficie, la emoción de una nueva relación de este tipo a menudo no parece ser motivo de alarma. Sin embargo, después de la excitación inicial, cuando la víctima muestra interés o preocupación por algo más allá de su nueva pareja, el manipulador puede mostrar ira, comportamiento pasivo-agresivo o acusar a las víctimas de egoísmo. Si la víctima no cumple con las demandas, comienza la etapa de devaluación: el abusador retira todo afecto o refuerzo positivo y en su lugar castiga a la víctima con lo que considere apropiado: gritos, reprimendas, juegos mentales, trato silencioso o incluso abuso físico.

Featuring perspectives from Dr Bita Fakhri, including the following topics: Overview of select presentations from ASH 2023; recent FDA approval of lisocabtagene maraleucel (0:00) 6-year follow-up from the Phase III CLL14 trial of first-line venetoclax/obinutuzumab versus chlorambucil/obinutuzumab for chronic lymphocytic leukemia (CLL) (7:36) Updates from ASH 2023 from the Phase III FLAIR study of minimal residual disease (MRD)-guided ibrutinib in combination with venetoclax for previously untreated CLL (13:28) 57-month follow-up from the Phase III GLOW trial of fixed-duration ibrutinib/venetoclax for previously untreated CLL (22:28) Current clinical role of MRD testing for CLL (28:11) Key findings from 5-year follow-up of the Phase II CAPTIVATE study for patents with CLL/small lymphocytic leukemia (SLL) with relapse after first-line fixed-duration ibrutinib/venetoclax (36:43) 6-year update from the Phase III ELEVATE-TN trial of acalabrutinib with or without obinutuzumab for treatment-naïve CLL (41:57) Updates from ASH 2023 for the management of relapsed/refractory CLL (54:30) Recent updates for the management of double-refractory CLL (58:05) Novel therapies under investigation for patients with CLL/SLL (1:10:57) Key findings guiding the clinical management of Richter's transformation (1:13:44) Case: A man in his early 80s with IGHV-unmutated del(17p) CLL experiences disease progression 3 years after completing second-line venetoclax-based therapy (1:22:17) CME information and select publications

Join Dr. Scales and Dr. Crabb as they delve into the impactful work of UNLV's Service Learning and Leadership (SLL) programs with their special guest, Rian Satterwhite. From fostering leadership development to providing vital support for students facing basic needs insecurities, such as food and housing, the SLL office plays a crucial role in creating a nurturing environment for student success. Discover how these programs not only address immediate needs but also foster a sense of belonging and community, ultimately empowering students to thrive academically and personally. Explore the transformative stories and learn how you can contribute to this vital initiative.

Please visit nascentmc.com/podcast for all the details.  Go to learnAMAstyle.com for lots of freebies on AMA Style and the use of AI in medical writing and editing Here is information on the latest US FDA approvals, the week of March 11 – March 15, 2024 Liso-cel for CLL/SLL   - The FDA approved lisocabtagene maraleucel (liso-cel; Breyanzi) for adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have received at least two prior therapies. It is a CAR T-cell therapy that modifies patient's T cells to target tumor antigens. The approval was based on the TRANSCEND CLL 004 study, showing a 20% complete response rate and a median duration of response not reached by the data cutoff. Tislelizumab for Esophageal SCC   - Tislelizumab-jsgr (Tevimbra) received FDA approval for unresectable or metastatic esophageal squamous cell carcinoma (ESCC) patients after prior systemic chemotherapy. The approval was based on the phase 3 RATIONALE 302 trial, which showed significant improvement in overall survival compared to chemotherapy (8.6 months vs. 6.3 months). This marks a critical advancement for patients with limited treatment options after first-line failures. Resmetirom for NASH   - The FDA approved resmetirom (Rezdiffra) for adults with non-cirrhotic non-alcoholic steatohepatitis (NASH) with moderate to advanced fibrosis, to be used alongside diet and exercise. This is the first medication approved to directly address liver damage in NASH patients with significant liver scarring, acting as a partial activator of a thyroid hormone receptor to reduce liver fat. The approval, based on a 54-month trial, used a surrogate endpoint at 12 months to demonstrate improvement in liver scarring and inflammation. Maralixibat for Cholestatic Pruritus   - Maralixibat (Livmarli) oral solution was approved for treating cholestatic pruritus in patients aged 5 years and older with progressive familial intrahepatic cholestasis (PFIC). It is an orally administered ileal bile acid transporter inhibitor, showing efficacy in the Phase 3 MARCH clinical trial across various genetic types of PFIC. Additionally, a higher concentration formulation is under consideration to extend its use to younger PFIC patients. Guselkumab for UC   - A supplemental Biologics License Application (sBLA) has been submitted for guselkumab (Tremfya) for treating adults with moderate-to-severely active ulcerative colitis (UC). The submission is based on the QUASAR program results, demonstrating significant clinical remission at Week 44 compared to placebo. Guselkumab, a novel IL-23 inhibitor, has previously been approved for moderate-to-severe plaque psoriasis and active psoriatic arthritis, marking its potential expansion into UC treatment.  

This week, we start a new series, this time all about the ins-and-outs of chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL)! Whether practicing general internal medicine, hospital medicine, or hematology/oncology, you will likely come across a patient with CLL. First, we go through initial diagnosis of this disease! Content: - What is CLL? How is this different than SLL?- What is the approach to diagnosis?- Do you need a bone marrow biopsy? Imaging?- How do we prognosticate patients? - Are smudge cells always suggestive of CLL? ** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast

Corinne wasn't feeling well this week, so Ayanni called in the cavalry. This episode, she's joined by her spouse (and friend of the show) Andrew Cooper to talk about the new action-dramedy series, Mr. and Mrs. Smith. They give their general impressions, think about the series' adaptation choices, and muse about the show's depiction of married life.  Show Notes: Other Lit Mentioned this episode: Jujutsu Kaisen, Spider-man: Into the Spiderverse, Mr. and Mrs. Smith (2009), Skip and Loafer, Dungeon Meshi, Tell Me That You Love Me, Let's Talk About Chu, The Dark Knight Trilogy, Ironman, Pen15, Blue Eyed Samurai, Pluto, Atlanta On Future SLL Episodes: Hadestown, Divorce Comedies, and A Court of Thornes and Roses Don't forget to subscribe to Sex. Love. Literature! You can find us on Instagram and Threads @SexLoveLit, and on Tumblr @SexLoveLitPodcast Our cover art is by Charcooll (⁠⁠https://www.instagram.com/charcooll/⁠⁠). The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US SLL is a podcast relishing the romantic, the sexy, and the scandalous in pop-culture. English academics by day and podcasters by night, hosts Ayanni and Corinne take a semi-scholarly look at why the “sex-stuff” in media matters in the bedroom—and beyond. Episode Chapters: 00:00 Introduction 01:07 Saying Hi to Andrew 05:51 What's Sparking Joy 15:20 Introducing Mr. and Mrs. Smith 19:54 First Impressions 24:43 Spoiler Discussion Begins 1:05:47 Coming Up on SLL

It wasn't even two weeks into the new year when the Food and Drug Administration made their first FDA approval. In this case, it was a Keytruda regimen for certain patients with gynecologic cancers. We at CURE® spoke with an the primary investigator on the study leading to the approval about what patients need to know about the latest new indication.  Also last week, we highlighted the Lymphedema Treatment Act and spoke to an expert about the new law.  Another story in the regulatory space: the FDA granted a Fast Track designation to speed up the review of a novel drug used to treat patients with relapsed or refractory CLL or SLL.  Finally, research from the American Cancer Society showed that Medicaid expansion states tended to have improved post-surgical outcomes in patients with non-small cell lung cancer.   Keytruda Plus CRT Offers ‘Better Chance of Cure' in Advanced Cervical Cancer The Food and Drug Administration has granted approval for Keytruda (pembrolizumab) in combination with chemoradiotherapy for the treatment of stages 3 to 4A cervical cancer, marking the first approval of an anti-PD-1 therapy with chemotherapy for this patient population and the third FDA approval for treating cervical cancer with Keytruda.  This week, I spoke with Dr. Linda R. Duska, a gynecologic oncologist and principal investigator on the study leading to the approval, who discussed the KEYNOTE-A18 trial, which enrolled 1,060 patients and demonstrated a 30% decrease in progression for those receiving the combination of Keytruda and chemotherapy. The overall survival data is not yet mature, but the treatment showed a 41% reduction in the risk of disease progression or death. While Dr. Duska emphasized that cervical cancer is preventable thanks to a safe and effective vaccine, she said that for patients with the disease, this new regimen is particularly exciting.  January is also Cervical Cancer Awareness month, so definitely stay tuned to curetoday.com for more of our coverage on the disease.  Medicare Must Now Cover Lymphedema Treatment Garments The Lymphedema Treatment Act, signed into federal law on Dec. 23, 2022, is now in effect as of Jan. 1, 2024, allowing Medicare coverage for doctor-prescribed compression supplies for patients experiencing. The bill encompasses standard and custom-fitted gradient compression garments and other approved items prescribed by healthcare professionals to treat lymphedema. Now basically what that means is that patients insured by Medicare Part B can now have their lymphedema garments covered by insurance.  This coverage is expected to ease financial burdens on patients, especially as these garments can be expensive.  I spoke with Joanna Fawzy Doran, CEO of Triage Cancer, who emphasized the importance of patient and provider awareness about coverage rights, appealing denials and navigating the process. Although the law does not mandate private insurers to cover compression sleeves for lymphedema patients, Doran noted that Medicare's coverage sets a precedent for broader access in the future. FDA Grants NX-5948 Fast Track Designation for R/R CLL, SLL The FDA has granted Fast Track designation to NX-5948, a novel drug, for adults with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma who have previously undergone two lines of therapy, including a BTK inhibitor and a BCL2 inhibitor.  Fast Track designation aims to expedite the development and review of drugs addressing serious conditions with unmet medical needs.  NX-5948 is currently in a Phase 1a/1b clinical trial, with initial findings presented at the 2023 American Society of Hematology (ASH) annual meeting indicating safety, tolerance, and clinical activity. The drug showed no dose-limiting toxicities or treatment-related side effects leading to discontinuation, and the most common side effects were purpura/contusion, nausea, and thrombocytopenia.  Medicaid Expansion May Decrease Early Mortality in Some With NSCLC States with Medicaid expansion tended to have a significant decrease in early, postoperative mortality from non-small cell lung cancer, according to recent research.  The research focused on nearly 15,000 patients undergoing surgery for NSCLC, with 62.1% residing in states supporting Medicaid expansion. The study found notable reductions in 30-day and 90-day postoperative mortality in patients with stages 1, 2, or 3 NSCLC in expansion states. Patients in non-expansion states were found to be younger, non-Hispanic Black, uninsured, and with comorbidities.  The study also evaluated changes in early mortality before and after the Affordable Care Act (ACA) implementation, showing a decrease in the 30-day mortality rate in expansion states from 0.97% to 0.26% after the ACA. Now, advocates, including the American Cancer Society, continue to emphasize the importance of expanding Medicaid eligibility to improve health outcomes.  For more news on cancer updates, research and education, don't forget to subscribe to CURE®'s newsletters here.

Patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) have poor outcomes after the failure of covalent Bruton's tyrosine kinase (BTK) inhibitor treatment, and new therapeutic options are needed. Pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor, was designed to re-establish BTK inhibition.

In a multinational, Phase III, head-to-head trial, ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, was compared with zanubrutinib, a BTK inhibitor with greater specificity, as treatment for relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). In prespecified interim analyses, zanubrutinib was superior to ibrutinib with respect to overall response (the primary endpoint).

This past weekend, the CURE® staff was busy covering the American Society of Hematology (ASH) Annual Meeting. ASH is the largest blood cancer conference in the country, and thousands of abstracts were presented. Now, we're bringing you some of the highlights from the conference. And, to view all of our conference coverage, be sure to check out curetoday.com/conference Navitoclax Plus Jakafi Improves Spleen Volume Reductions in Myelofibrosis Spleen enlargement is a common and often problematic symptom of myelifbrosis. However, recent findings from the phase 3 TRANSFORM-1 trial found that combining the novel drug, navitoclax with Jakafi was successful in reducing spleen volume in this patient population. The main outcome that the researchers were looking at in this study was the percentage of patients who had a spleen volume reduction of 35% or more at certain time points. Findings showed that by week 24, 64.2% of patients who had the navitoclax regimen experienced this level of spleen reduction, compared to only 31.5% of patients who received placebo plus Jakafi — that's a significant overall difference of 31%. Navitoclax is not currently approved in any indication, but AbbVie, the pharmaceutical company behind the agent, plans to submit the drug for FDA approval in 2023, pending study results. Brukinsa Lengthens Time to Progression in Relapsed/Refractory CLL, SLL There are currently three BTK inhibitors for the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL and SLL, respectively), though a lack of research exists that compares these drugs head-to-head. Now, the phase 3 ALPINE trial was the first study to directly compare two BTK inhibitors, Brukinsa and Imbruvica, in patients with relapsed or refractory CLL or SLL. Findings showed that after about 39 months of follow-up, patients given Brukinsa tended to live longer before death or disease progression — a statistic experts refer to as “progression-free survival.” In the general patient population, Brukinsa reduced the risk of disease progression by 32%, and for patients with 17p deletion and/or TP53 mutations — subtypes that typically indicate aggressive disease — there was a 48% reduction in the risk of disease progression. Abecma May Improve Quality of Life in Previously Treated Myeloma The phase 3 KarMMA-3 trial showed that Abecma significantly improved symptoms, functioning and health-related quality of life in patients with relapsed or refractory multiple myeloma who previously underwent two to four prior treatments. Abecma is a CAR-T cell therapy, which is a newer type of treatment for blood cancers. It involves taking patients' blood out, and re-engineering their T cells to find and fight cancer. After they're multiplied, those new T cells are infused back into the patient. Findings from the KarMMA-3 trial showed that Abecma led to improvements in fatigue and pain compared with other standard regimens in this patient population.

This episode, on the recommendation of an SLL listener, we're excited to do a deep dive into the Japanese Drama, Rinko-San Wants to Try. We get into how the show complicates conceptions of virginity, plays with the friends with benefits trope, and maybe get in our feelings a lil bit about a second female lead who really got under Ayanni's skin. As two people who study, analyze, and have a literal podcast about media, we stand in solidarity with the SAG-AFTRA strike. Without the labor of the actors currently on strike–along with their counterparts in other industries/countries, who also deserve fair wages and labor protections–none of the works we discuss here or in other episodes would exist. Lit discussed this episode: Get Up EP by NewJeans, Pop Culture Happy Hour (this episode specifically: https://www.npr.org/2023/08/15/1193958358/newjeans-is-a-new-kind-of-k-pop-juggernaut), My Dearest, Hit the Spot, Because This is My First Life, Lost You Forever, Friends With Benefits, No Strings Attached, Nevertheless..., Extraordinary Attorney Woo, Sex Education Bonus reading (aka works cited & consulted): Jones, Gretchen. "'Ladies' Comics': Japan's Not-So-Underground Market in Pornography for Women." U.S.-Japan Women's Journal, English Supplement, no. 22, 2002, pp. 3-31. Lieber-Milo, S. “Cute at an Older Age: A Case Study of Otona-Kawaii”. Mutual Images Journal, no. 10, Dec. 2021, pp. 93-108, doi:10.32926/2021.10.lie.otona. Sato, Kumiko. "From Hello Kitty to Code Row Kewpie: A Postwar Cultural History of Cuteness in Japan." Asian Intercultural Contacts, vol. 14, no. 2, 2009. https://www.asianstudies.org/wp-content/uploads/from-hello-kitty-to-cod-roe-kewpie-a-postwar-cultural-history-of-cuteness-in-japanA.pdf Don't forget to subscribe to Sex. Love. Literature! You can find us on Instagram and Threads @SexLoveLit. The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License;  https://creativecommons.org/licenses/by/3.0/deed.en_US Recorded September 2023 SLL is a podcast relishing the romantic, the sexy, and the scandalous in pop-culture. English academics by day and podcasters by night, hosts Ayanni and Corinne take a semi-scholarly look at why the “sex-stuff” in media matters in the bedroom—and beyond.

Content warning: This episode contains a very brief discussion of sexual assault from (27:14 - 27:21). Happy 3rd Birthday to Sex. Love. Literature!

Today's story: Changes to Foreign Language Bonuses

Dave and Lorenzo nerdout about kids and their activities then they get into, raising a family, starting out as a 7th grade football coach, 2 SLL championships, moving to varsity, the triple option, coaching your sons at the varsity level, watching devastating injuries, changing careers, working with great head coaches and so much more!

Content warning: While we don't discuss sexual assault in detail, we do mention it a few times, since it often comes up in conversations about consent. We've got a treat for you all this episode! Along with your usual fabulous co-hosts, we're joined by filmmaker, writer, and scholar Michele Meek to discuss the Netflix show Sex Education. In the first of two episodes with Michele, we first learn about her exciting new book, Consent Culture in Teen Films: Adolescent Sexuality in US Movies. Then, in our discussion proper, we introduce Sex Education; decide whether or not we really like the main character, Otis, and other members of the ensemble cast; and work through some of the secondhand embarrassment often associated with teen sex comedies.  Mark your calendars and turn on your SLL notifications: "E30 Sex Education (Part 2) feat Dr. Michele Meek" will drop on July 28th, 2023! To learn more about Michele and her work, visit MicheleMeek.com. Corinne got really excited during What's Sparking Joy and it ran a little long, but if you want to get right to the Sex Education content, you can jump (15:35 - 24:48). Also, if you're a Sex Education fan and want to skip the background/character info, you can bypass (25:49 - 30:48). As two people who study, analyze, and have a literal podcast about media, we stand in solidarity with the WAG and SAG-AFTRA strikes. Lit discussed this episode: The Graceling Trilogy, Vinland Saga (Season 2), To the End of the Moon, The End of Sex Don't forget to subscribe to Sex. Love. Literature! You can find us on Twitter, Instagram, and Threads @SexLoveLit. The SLL Theme music is “Pluck It Up” by Dan Henig. What's Sparking Joy BGM is "Candy-Coloured Sky" by Catmosphere |  https://soundcloud.com/ctmsphr; Released by Paper Crane Collective;  Music promoted by https://www.free-stock-music.com; Creative Commons  Attribution 3.0 Unported License;  https://creativecommons.org/licenses/by/3.0/deed.en_US Episode was recorded in May 2023.

Please visit answersincme.com/FSV860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in hematologic cancer discusses the use of chimeric antigen receptor (CAR) T cell therapies in B-cell lymphoma. Upon completion of this activity, participants should be better able to: Recognize the clinical rationale for using chimeric antigen receptor (CAR) T cell therapies for relapsed/refractory indolent follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL); Describe the clinical profiles of approved and emerging CD19-directed CAR T cell therapies for relapsed/refractory indolent FL and CLL/SLL; and Outline clinical considerations for the use of CD19-directed CAR T cell therapies for relapsed/refractory indolent FL and CLL/SLL.

Episode Summary Hosts Nicholas Gandolfo, Vice President, Corporate Solutions Aditi Bhatia, Senior Regional Manager, Corporate Solutions What Will the EU Green Bond Standard Mean for the Market?  With the European Union's Green Bond Standard set to come into effect sometime next year, we look at what it could mean for the global sustainable finance market more broadly. Although the highly anticipated framework is expected to be the gold standard for what we see in the market going forward, there are ongoing concerns about its usability. Some market participants are worried about the potential difficulty in meeting all the requirements of the Green Bond Standard and whether the standard is too prescriptive in its requirements to set up a framework.   Sustainable Finance Meets AI   The sustainable debt market continues to see innovations in the types of projects being funded. One example is the use of green bonds to raise money for artificial intelligence (AI) projects related to green or social initiatives. The green bond issuance highlighted in this episode will finance AI projects related to improving the environmental performance of buildings through data analytics and energy management software. Using AI to support corporate sustainability improvements is not new, but funding such projects using sustainable debt instruments could be the next wave.  Changes Coming to the Podcast! Our sustainable finance insights show will be taking a break for the summer. We'll be back this fall with some exciting changes to bring you more ESG, sustainable finance and responsible investing insights. In the meantime, please subscribe to ESG in Conversation on your favorite podcast platform and enjoy new episodes each month!  Key Moments 0:00:49  Market overview  0:01:36  CBI Q1 highlights report  0:03:04  LMA sustainability linked loan drafting model  0:03:28  Sustainable bond market risks  0:04:44  Gender-focused social bonds   0:05:37  Transition plan guidelines  0:05:58  Debt for nature swaps  0:06:23  IRENA report on the cost of energy transition  0:07:00  New CBI reports  0:07:42  SLB and SLL overview  0:11:35  Audience questions  0:16:08  Green bonds and loans overview  0:19:25  Labeled products, transition bonds and regulatory updates    Links to Select Resources Climate Bonds Initiative – Sustainable Debt Market Summary Q1 2023  Environmental Finance – LMA Publishes ‘Vital' Sustainability-Linked Loan Drafting Model  Morningstar Sustainalytics – Anticipating the Inevitable: What to Expect from the European Green Bonds Regulation   Responsible Investor – Details Emerge on EU Green Bond Standard as Concerns About Uptake Remain  Environmental Finance – Sustainable Bond Market Risks Fragmentation Amid ‘Regulatory Overload'  BusinessWorld – No Plans for Follow-Up Offer of Catastrophe Bonds – De Leon  WION – Bhutan Takes Steps to Set Up Green Cryptocurrency Mining Operation: Report  Environmental Finance – ‘Huge Opportunities' for Gender-Focused Corporate Sustainable Bond Growth  Environmental Finance – GSAM: 36% of European Investors Ready to Invest in Social Bonds  Forbes – Companies Going Green Should Add Finance To Sustainability Strategies  Eco-Business – The Next Wave of Greenwashing: Offsets, Competitor Claims and ‘Transition-Washing'  Environmental Finance – Banks Call on EU to Provide Transition Plan Guidelines  Environmental Finance – Credit Suisse Arranges $1.6bn Debt-for-Nature Conversion With Ecuador  IRENA – Low-Cost Finance for the Energy Transition  Climate Bonds Initiative Reports  Concrete Policies to Underpin the Cement Transition  ASEAN Sustainable Finance State of the Market 2022  Property Certification Opportunities in Tokyo  Sneak Peek: The CBI's Resilience Taxonomy Blueprint  Sustainalytics Second-Party Opinions  TDC NET Sustainability-Linked Finance Framework Second Party Opinion  UMH Properties Inc. Sustainable Finance Framework Second-Party Opinion  Grupo Bimbo Sustainable Financing Framework Second-Party Opinion  More Episodes

The traditional long summer break from school in the U.S. can mean fun in the sun—and summer learning loss (SLL). While SLL is a documented phenomenon, not all K-12 students lose the same skills and knowledge over the summer. In fact, some make gains over the summer holiday. One of the most important things students can do to improve is read. And reading can be a powerful driver of learning for adults as well as K-12 students. In this episode of the Leading Learning Podcast, co-hosts Jeff Cobb and Celisa Steele offer a preview of their summer reading list, each sharing one book of nonfiction, one of fiction, and a wildcard—with a few bonus books thrown in for good measure. Show notes and a downloadable transcript are available at https://www.leadinglearning.com/episode362.

Episode Summary Hosts: Sabrina Tang Sales Associate, Sustainable Finance Solutions Nicholas Gandolfo, Vice President, Corporate Solutions   Is the Sustainable Finance Market Rebounding in 2023? In this month's episode, Nick and Sabrina dig into the sustainable finance market's rebound in Q1. Despite the market pressures caused by inflation and the banking shake-ups at UBS and Credit Suisse, sustainable finance activity saw an upward trend in the first part of the year. Although Nick and Sabrina stop short of making any predictions about where volumes will land by the end of the year, they do note some interesting dynamics in the market: green use of proceed bonds remain strong, social and sustainability focused bonds are down slightly, and sustainability-linked finance appears to be gaining some ground again despite continued market scrutiny. Scrutiny Continues for Sustainability-Linked Bonds Despite the rebound in sustainability-linked bond (SLB) activity in Q1 this year, concerns remain about this sustainable debt instrument. Several recent articles and reports discuss the credibility of SLB targets, whether coupon rates offer enough of a penalty if targets are missed, and whether the performance targets and indicators have an impact on sustainability. There's also some media coverage on SLB issuers missing their stated sustainability performance targets. Although not ideal, missed targets among SLB issuers could be viewed as a sign of their rather than an indication of something being fundamentally wrong. For issuers considering sustainability-linked debt instruments and seeking additional guidance, check out the latest market references from Climate Bonds Initiatives (CBI). The Sustainable Sovereign Debt Club Continues to Grow CBI's 2022 market summary highlights the growth of sovereign bond issuances. This is great to see because sustainable debt from sovereigns catalyzed the market in many cases. Sabrina highlights the recent activity from Turkey, Austria, Italy, and Cyprus as well as the sovereign green bond program being considered by the Australian government. In addition to more countries seeing the opportunities in sustainable debt instruments, regulators across a growing number of jurisdictions are ramping up sustainable finance activities in their countries. Developments are ongoing in India, Indonesia, Malaysia, Sri Lanka, Japan, and Vietnam to name just a few.   Key Moments 0:00:59 Market overview 0:02:07 Q1 market overview 0:03:25 CBI 2022 state of the market report 0:05:22 Continuing SLB scrutiny 0:06:46 Climate transition plan transparency 0:08:34 More updates to the EU taxonomy 0:09:34 Additional articles and reports to read (see links below) 0:11:34 SLB and SLL overview 0:14:15 Audience questions 0:18:14 Green bonds overview 0:21:13 Green loans overview 0:22:30 Social bonds and loans overview 0:23:25 Labeled products, transition bonds and regulatory updates     Links to Select Resources Climate Bonds Initiative – Green and Other Labelled Bonds Fought Inflation to Amass USD858.bn Volume in 2022 Climate Bonds Initiative – Sustainable Debt: Global State of the Market 2022 Environmental Finance - ‘It's time to stop step-up-only sustainability-linked bonds' Environmental Finance – Union Investment: SLBs Can Have Impact Environmental Finance – CBI Launch Sustainability-Linked Bond Certification Scheme Energy Monitor – Are We About to See a Surge in Sovereign Sustainability-Linked Bonds? Environmental Finance – Sustainability-Linked Targets Could Add ‘Discipline' in Green Bond Markets Retail Banker International – CaixaBank Rolls Out Metaverse Initiative to Promote Sustainability Responsible Investor – Market Hails ‘Surprisingly Helpful' SFDR Clarifications from European Commission GreenBiz – Should Sustainability Teams Report Directly to the CEO? Climate Action 100+ - Climate Action 100+ Releases the Latest Evolution of the Net Zero Company Benchmark Financial Times – New Standards Keep the Greenwash off Green Bonds The Strait Times – Companies Risk Penalties as Asia and Australia Target Greenwashing Environmental Finance – ‘Greenwashing is rife' in Green Bonds, Says EU's Tang IPCC – AR6 Synthesis Report: Climate Change 2023 Environmental Finance – Nature-Related Sovereign Issuances Set to Grow, Insight Predicts Climate Bonds Initiative – Sustainability-Linked Debt Instrument Certification Sustainalytics Second-Party Opinions Hera Group's Green Financing Framework Second-Party Opinion Council of Europe Development Bank Social Inclusion Bond Framework Second-Party Opinion More Episodes

Episode Summary  Hosts:  Nishant Bhagchandani, Sales Manager, Sustainable Finance Solutions  Nicholas Gandolfo, Vice President, Corporate Solutions     Regulation, Guidance and Taxonomy Updates Keep Market Participants on Their Toes   In this episode, Nick and Nishant discuss the flurry of updates in the sustainable finance regulation and guidance space. The European Union has reached a long-awaited deal on the first set of comprehensive rules for issuing green bonds. Although voluntary, the EU Green Bond Standards will help investors identify high-quality green bonds and may set a precedent for other jurisdictions.   The Green Loan Principles, Social Loan Principles, and Sustainability-Linked Loan Principles were also recently updated to align more closely to current market practice and provide additional guidance to borrowers (e.g., recommendations that borrowers obtain an independent external review of their green, social and sustainability-linked loan processes). Other updates include recommendations for the sustainable finance taxonomies being developed in Australia and Canada, as well as the new draft version of the Taskforce for Nature-related Financial Disclosures (TNFD) framework.         What the Final TNFD Framework Could Mean for Sustainable Finance   With the release of the fourth beta framework from the TNFD, market participants eagerly await the final version, due to be published this fall. This latest beta release includes a full draft reporting framework and a set of disclosure metrics, along with assessment metrics to be used by companies. The disclosure metrics will also include some core measures which are applicable to all sectors. The final framework will help to standardize the sustainability metrics companies report on, making them usable in sustainability-linked instruments and speeding up the framework's adoption.     Key Moments  0:00:59  Market overview  0:02:32  Market forecast  0:03:22  SVB failure and climate tech  0:04:05  Morningstar Sustainalytics launches Low Carbon Transition Ratings  0:04:37  Relinking in sustainable finance  0:05:11  TNFD release beta version 4 of framework  0:05:56  Insights from Kanga News Sustainable Debt Conference  0:06:30  Taxonomy developments in Australia and Canada  0:07:24  Agreement of EU Green Bond Standards  0:08:33  High Seas Treaty will boost blue bond issuance  0:08:45  SLBs as a hedge against sustainability policies  0:09:00  Transition finance standards  0:09:12  Updated principles for green, social and sustainability-linked loans  0:10:58  SLB and SLL overview  0:13:48  Audience questions  0:17:43  Green bonds overview  0:20:56  Social bonds and loans overview  0:22:40  Labeled products, transition bonds and regulatory updates      Links to Select Resources  JD Supra – Asian ESG Debt Markets Take a Breath After Record Run  Bloomberg – Green Bonds Turbo Charge ESG Debt Sales to Busiest February Ever  ESG Clarity – Natixis Q&A: ‘Liquidity Will Be Driven by ESG Transparency and Clarity'  Environmental Finance – Credit Suisse: Another Headwind for 'Green' AT1 Bonds   Morningstar Sustainalytics Launches its Low Carbon Transition Ratings  Bank of China Ltd Announcement – Sustainability Re-Linked Notes Coupon Adjustment: Annual Coupon Adjustment of Sustainability Re-Linked Notes  Environmental Finance – Forthcoming TNFD Metrics Would Work in Sustainability-Linked Instruments  Environmental Finance – Traffic-Light System Recommended for Australia's Taxonomy   Environmental Finance – EU Green Bond Standard: Provisional Deal on Landmark Regulation Agreed   ESG Clarity – High Seas Treaty Will Boost Interest, Access and Issuance of Blue Bonds  Climate Bonds Initiative – India's Debut in the Sovereign Green Bond Market: First Deal Landed a Greenium!  IRENA – Investments in Renewables Reached Record High, But Need Massive Increase and More Equitable Distribution  International Energy Agency – Global CO2 Emissions Rose Less Than Initially Feared in 2022 as Clean Energy Growth Offset Much of the Impact of Greater Coal and Oil Use  Climate Bonds Initiative – Climate Bonds Standard Expands With New Agri-Food Transitions Criteria: Commodity and Supply Chain TWGs And IWGs Now Onboarding    More Episodes  

Since the publication of the original sustainability-linked loans (SLL) principles and guidance by the Loan Market Association (LMA) and Loan Syndications and Trading Association (LSTA), there has been a significant increase in volumes of sustainability-linked financing. Lenders and borrowers have used the credibility and flexibility of this loan product to respond to the changing financial landscape and stakeholder demands, whilst developing their sustainability strategies and policies. The LMA and LSTA are set to release revised SLLPs this and are also planning to release a set of standardised model terms for SLLs in facility agreements that will play a crucial role in providing structure, consistency and guidance to the growing SLL market. In this podcast, the hugely important loan product is discussed by our Financial Services partner, Sukhvir Basran, who is joined by Tess Virmani of the LSTA and Gemma Lawrence-Pardew of the LMA. We hope you find this discussion as insightful as those who attended the session in our London office. We are always happy to answer any questions you may have on the topic.

Episode Summary  Hosts:  Winnie Chung, Senior Associate, Corporate Solutions  Nicholas Gandolfo, Vice President, Corporate Solutions   Growing Innovation with Sustainable Finance Instruments  In this episode, Nick and Winnie chat about the latest news and transactions in the sustainable finance space. With a focus on innovation, they discuss the new ways in which issuers are leveraging sustainable finance instruments to fund their green and social projects. For instance, the World Bank's recent bond issuance will forgo investor coupon payments, instead using the funds to finance a project manufacturing water purifiers in Vietnam. Using purifiers will replace biomass burning (traditionally used to boil water to make it safe to drink), resulting in lower carbon emissions. The carbon emissions saved will be turned into carbon credits and sold to fund a coupon payment to bond investors. Nick also notes innovation picking up in the areas of blue bonds and the maritime economy as well as biodiversity-focused finance activities.    Investors Swing Back to Use of Proceed Instruments  Winnie and Nick also touch on the growing ambivalence towards sustainability-linked instruments. In 2022, sustainability-linked bonds and loans seemed to lose some of their appeal as scrutiny of targets and performance indicators intensified and accusations of greenwashing arose. Adding to the discontent – slipping targets. Analysis from Barclays finds that nine out of 12 SLBs with target measurement dates in 2023 are off track to hit those targets. Consequently, we're seeing a swing back toward traditional use of proceed instruments. This is particularly true within the green bond market which took less of a hit compared to other types of labelled bonds in 2022. With more green bond disclosure guidance and regulations expected from more jurisdictions, such as India, Bolivia, EU and Latin America, investors will likely continue to seek security in the more structured green bond market.   Key Moments 0:02:20  Market overview  0:02:37  Expected market rebound  0:03:15  Innovative structure from World Bank  0:04:03  Swing back to use of proceeds?  0:04:23  Innovative structure from ENEL  0:05:10  Blue and biodiversity activity  0:05:31  Continued scrutiny of SLLs and SLBs  0:06:40  ASEAN developments  0:07:34  New CBI reports  0:08:04  SLB and SLL overview  0:11:52  Green bonds overview  0:17:35  Green loans overview  0:17:57  Audience questions  0:21:05  Social bonds and loans overview  0:22:03  Labeled products, transition bonds and regulatory updates    Links to Select Resources Bloomberg – ESG Bond Sales Hit 12-Month High; Debut Deals Pile Up  Environmental Finance – Sustainable Bonds Insights 2023 Published Environmental Finance – World Bank Issues ‘Unique' Carbon Credit-Linked Bond Environmental Finance – IFC adds ‘Blue', Biodiversity Projects to Green Bond Framework UN Environment Programme – Countries Search for Financing to Counter Biodiversity Crisis  Responsible Investor – SLB Issuers ‘Likely to Miss Majority of 2022 and 2023 Targets' Environmental Finance – SLB Issuers ‘Lose Their Halo,' says HSBC LSTA – Drafting Guidance for Sustainability-Linked Loans (Feb 17, 2023) Environmental Finance – Philippines Opens Consultation on Sustainability-Linked Bonds Standards Financial Times – Sustainability Bond Market Stumbles as Investors Get Picky CarbonCredits.com – JBS “Green Bonds” and GHG Emissions Under Investigation  Bloomberg – Barclays Sees Real Greenwashing Risk in ESG Debt-Swap Market Climate Bonds Initiative – Sustainable Agriculture Brief Climate Bonds Initiative – Scaling Credible Transition Finance – ASEAN Edition Capital Monitor – Why Japan Embraces Transition Bonds  Business Standard – SEBI Asks Issuers for Additional Disclosure in Guidelines on Green Bonds ESG Clarity – Mandatory Climate Finance Disclosure ‘Evens Playing Field' for Australia Sustainalytics SPOs: Nokia Sustainable Finance Framework Second Party Opinion State Bank of India ESG Financing Framework Second-Party Opinion Hertz Green Finance Framework Second-Party Opinion    More Episodes  

Episode Summary Hosts Nicholas Gandolfo, Vice President, Corporate Solutions Sabrina Tang, Sales Associate, Corporate Solutions In this episode, Nick and Sabrina reviewed what's new in sustainable finance and shared some notable deals and transactions that have hit the market. They discussed the overall decline of global bond markets and expressed some optimism for the year to come, as sustainability is a central issue for investors, companies and governments and is still closely tied to capital markets. They also shared research on the carbon performance of food producers and a report on how to scale credible transition finance among countries in Southeast Asian.  Sustainable Market Hopes for 2023  If you've been following sustainable finance market activities, it's no surprise that 2022 was not a great year overall. Markets were down in volume for the first time in 11 years. According to figures from Environmental Finance, total annual sustainable bond issuance fell 19%, from US$1.05 trillion in 2021 to US$845 billion in 2022. Social, sustainability and sustainability-linked bonds were hit hardest – down about 25% compared to 2021, while green bonds fared a bit better with a more modest 14% issuance decline.  Despite the lower issuance volumes, there is hope for a rebound in 2023 as overall markets stabilize and issuers seek financing. This year may see use of proceed instruments like green bonds continue to gain ground compared to performance based, sustainability-linked bonds. We may also see more transition deals, social and biodiversity focused activity, as well as more complicated transactions going to market. It's still early days, so let's see how things develop.  Updated Standard for Reporting Financed Emissions in Sovereign Debt  If you're a bank trying to figure out how to report on your financed emissions, be sure to read through Partnership for Carbon Reporting Financials' (PCAF) recently updated standard. Global GHG Accounting and Reporting Standard for Financed Emissions addresses demands from financial institutions and provides a methodology to help investors in sovereign debt account and report greenhouse gas emissions. The methodology on sovereign debt includes bonds and loans of all maturities, however, only debt issued by the central bank on behalf of the sovereign would be covered. The methodology also requires reporting of scope 1, scope 2 and scope 3 emissions and recommends getting the information from countries' reported data via the United Nations Framework Convention on Climate Change. Key Moments 0:01:16 Market overview 0:03:24 COP15 insights 0:04:22 Australia sustainable finance taxonomy 0:05:04 BNP Paribas social impact bond 0:05:16 TPI paper on food producers' carbon performance 0:06:53 Updated PCAF standard 0:07:31 Banks' transition planning under scrutiny from ECB 0:08:05 Activity in carbon markets 0:08:45 Austria launches green commercial paper program 0:09:14 CBI paper on transition finance in ASEAN 0:10:17 SLB and SLL overview 0:15:34 Audience questions 0:21:00 Green bonds overview 0:23:56 Green loans overview 0:25:06 Social bonds and loans overview 0:27:38 Labeled products, transition bonds and regulatory updates   Links to Select Resources Environmental Finance – Annual Sustainable Bond Issuance Falls for First Time Since 2011 Bloomberg.com – Global Debt Market Lost at Least $75 Billion of Business in 2022 Reuters – ESG Watch: Despite Setbacks, Green Finance Ends 2022 in Good Health Global Capital – High Hopes for Corporate Issuance in 2023 Environmental Finance – COP15 Agreement 'Significant,' but Credit Impact Depends on Implementation Environmental Finance – Climate Change Litigation: 11 Key Cases for Insurers to Watch Australian Sustainable Finance Institute – Taxonomy Project Global Capital – Saving Biodiversity: The Next Mountain for Capital Markets Transition Pathways Initiative – TPI Carbon Performance Assessment of Food Producers: Discussion Paper Environmental Finance – PCAF Sovereign Debt Methodology Plugs Gap in Emissions Accounting, Says Allianz European Central Bank – Supervisory Priorities and Risk Assessment for 2023-2025 Environmental Finance – Carbon Markets Can Help Provide Nature-based Solutions The Hindu Business Line – Sovereign Green Bonds Will Act as Benchmark for Private ESG-linked Debt: RBI's Rao Global Capital – Austria to Launch Green Commercial Paper in 2023 Climate Bonds Initiative – Scaling Credible Transition Finance – ASEAN Edition Sustainalytics SPOs: UNIQA Green Bond Impact Report Mosaic Solar Green Use of Proceeds Securitized Bond (2022-3)

Episode Summary Hosts Nicholas Gandolfo, Vice President, Corporate Solutions Aditi Bhatia, Senior Regional Sales Manager, Corporate Solutions In this episode, our hosts Nick and Aditi discuss the recently held COP27 and COP15 conferences and what their outcomes could mean for green and social financing globally. They also touch on the concept of blended finance and how that might be used to support climate adaptation in emerging markets. Increasing activity among sovereigns is also discussed, as countries come to market more frequently with sustainable debt. Lastly, Nick and Aditi share a rundown of other notable sustainable finance transactions.  Climate High on the International Agenda  Given the current climate crisis, expectations were high for COP27. From an environmental standpoint, the final agreement was seen as a disappointment by some observers. However, the conference closed with a ground-breaking agreement to set up a loss and damages fund, which aims to provide financial assistance to countries vulnerable to, or impacted by, the effects of climate change. COP15, the United Nations Biodiversity Conference, also concluded late last year with a landmark agreement that includes measures to halt and reverse nature loss – such as putting 30% of the planet and 30% of degraded ecosystems under protection by 2030. The plan also includes a target of mobilizing at least US$200 billion per year from public and private sources for biodiversity-related funding. Finally, the G20 conference in Bali also turned its attention to issues around climate change, low-carbon transition, and climate adaptation.  Innovative Solutions to Fund Sustainable Development  With an estimated US$9.2 trillion needed to meet global climate and environmental goals,1 private and public sectors are looking for more ways to funnel money to finance mitigation and conservation efforts. To address this need, market participants are discussing innovative solutions like blended finance, which is the strategic use of development finance (such as public or philanthropic capital) and private investment capital to fund sustainable development projects in developing countries.2  A new crop of instruments is also emerging to offer potential solutions. This includes instruments like debt-for-nature swaps, a financial mechanism that allows portions of a developing country's foreign debt to be forgiven, in exchange for commitments of investment in biodiversity conservation and environmental policy measures.3 We anticipate seeing more variety in the types of instruments being developed to support conservation and climate adaptation in countries most vulnerable to climate change.  Check Out Our Special Episode on Sustainable Finance in the Metals and Mining Sector  In case you missed it, we recently took a deep dive into the sustainable and transition finance opportunities within the metals, mining and commodities sector. Our panel discussed key considerations for banks, issuers and investors interested in using sustainable finance instruments to help fund improvements across the sector and mitigate potential risks. The sector is incredibly important because of its crucial role in the global transition to a low-carbon economy. However, these companies face numerous environmental and social challenges, which if not managed effectively could negatively impact their access to capital. Listen here: Sustainable Finance Insights: Special Episode on Sustainable Finance in the Metals, Mining and Commodities Sector   Key Moments 0:00:51 Market overview 0:01:38 COP27 insights 0:03:48 G20 Summit 0:04:35 COP 15 insights 0:05:00 State of the bond market and outlook for 2023 0:05:56 Sovereigns' ambitions in sustainable finance 0:06:33 Social taxonomy update 0:06:52 Green bond tokenization 0:07:12 Emergence of blended finance 0:08:02 More activity in transition finance market 0:08:19 Market scrutiny of SLBs 0:10:08 ICMA paper on sustainable repos 0:10:34 Food security as social use of proceeds 0:10:54 More activity around carbon markets globally 0:11:15 PCAF publishes second version of Global GHG Account and Reporting Standard 0:11:48 CBI principles for transitioning agriculture sector 0:12:23 SLB and SLL overview 0:17:39 Audience questions 0:23:26 Green bonds overview 0:26:51 Green loans overview 0:28:50 Social bonds and loans overview 0:31:04 Labeled products, transition bonds and regulatory updates   Links to Select Resources IFLR - COP15: Financial Firms Look to Scale Up Nature Finance Bloomberg - Global ESG Bond Issuance Headed for First Full-Year Decline Ever GlobalCapital – Record Volumes Spark January Debate in FIG Market Responsible Investor – World Bank: Only 31 Southeast Asian Companies Have Issued Sustainable Debt Since 2017 OMFIF – Sovereigns Need to Show More Ambition With ESG Bond Frameworks GlobalCapital – ESAs Call for Evidence of Greenwashing Open Access Government – Social Taxonomy: A Step Towards Social Sustainability Environmental Finance – Banks Urged to Rework Financing Instruments for Climate Adaptation Blockchain News – HK to Issue Tokenized Green Bond, Open Market for Virtual Assets ETFs Trading China Dialogue – China's Central Bank to Focus on Transition Finance The Manila Times – ASEAN Launches Sustainable and Responsible Fund Standards Bloomberg Law – ESG-Linked Bonds Seen Stalling on Greenwash and Legal Fears Environmental Finance – Snam's Return to Transition Bonds ‘A Big Sign' SLBs are Under Pressure GlobalCapital – Crunch Time Coming for SLBs as First Step-Ups Appear The Business Times – ESG is Taking Over the Loan Market Environmental Finance – ICMA Principles Could be Adapted for ‘Sustainable Repos' Climate Home News – John Kerry: Carbon Offsets Can Help Wean Developing Countries Off Coal World Economic Forum – Climate Adaptation: The $2 Trillion Market the Private Sector Cannot Ignore Responsible Investor – Scope 3 Emissions Key to Financial Sector Net Zero Plans, says GFANZ Climate Bonds Initiative – Principles and Hallmarks for Transitioning Agri-Food Systems: Opportunities, Pathways and Actions Sustainalytics SPOs: AIB Green Bond Framework Second-Party Opinion Storebrand Green Bond Framework Volkswagen Aktiengesellschaft Green Finance Framework Second-Party Opinion City of Atlanta Social Bond Framework Second-Party Opinion CABEI Green and Blue Bond Framework Second-Party Opinion VPBank Social Finance Framework Second-Party Opinion   Sources 1Roston, E. 2022. “McKinsey Pegs the Price Tag for a Livable Climate at $9.2 Trillion a Year.” Bloomberg. January 25, 2022. https://www.bloomberg.com/news/articles/2022-01-25/mckinsey-pegs-price-tag-of-livable-climate-at-9-2-trillion-a-year 2 See OECD: https://www.oecd.org/development/financing-sustainable-development/blended-finance-principles/ and Bank of America: https://about.bankofamerica.com/en/making-an-impact/blended-finance 3 See Earth.org: https://earth.org/debt-for-nature-swaps/  

It's time for our yearly celebration of pop-culture: "What's Sparking Joy 2023!" We start off with a round of “What's Sparking Joy” for us in January, move on to thinking about our favorite pop culture of 2022, what we're looking forward to in 2023, and a round of pop-culture predictions. We also take a moment remembering KPOP! Broadway and our experience seeing the final performance of its run. (You can pre-order the original cast recording of KPOP! or stream the song "This is My Korea" to give the fabulous cast some love.) What media are you looking forward to this year? Some Episode Notes: Ayanni was so excited this episode, she forgot how to speak and count! The 4th anniversary of SLL with be this summer ❤️ ...and it's Lee Jae Wook

CME credits: 1.00 Valid until: 10-01-2024 Claim your CME credit at https://reachmd.com/programs/cme/individualized-approaches-in-cllsll-meeting-the-needs-of-your-patients-now-and-preparing-for-the-future/14730/ The emerging treatment landscape for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) has resulted in improved outcomes for patients. However, challenges remain when selecting the best frontline approach and now involve decisions about using a time-limited option or continued therapy model. Other challenges exist on relapse, so it's essential that providers understand the disease and patient factors that are critical when sequencing therapeutic agents. Join us in this Streaming National Broadcast that will help you meet the treatment needs of your patients with CLL/SLL both today and in the future.=

Episode Summary Hosts Nicholas Gandolfo, Director, Corporate Solutions Aditi Bhatia, Regional Sales Manager, Corporate Solutions In this episode, Nick and Aditi highlight developments in the sustainable finance markets as 2022 winds down. They note that global cumulative green bond issuance has surpassed the US$2 trillion threshold, marking another milestone for sustainable finance. They also discuss the diversification of key performance indicators used in sustainability-linked instruments, the growing opportunities for using sustainable finance as a tool to fund climate adaptation in emerging markets, and regulators' increasing focus on reporting for scope 3 emissions. Finally, they respond to audience questions about impact investing and sleeper sustainability-linked loans. Cumulative Issuance of Climate-aligned Bonds Passes $2 Trillion Mark According to the Climate Bonds Initiative, to date over US$2 trillion in greens bonds have been issued globally, marking another major milestone in sustainable finance. Despite broader market conditions resulting in lower volumes year-over-year, use of proceed bonds, such as green bonds, are rebounding slightly.  Using Sustainable Finance to Support Funding in Emerging Markets  When thinking about how to ensure a just transition, a recurring question is, "How can market participants initiate more financing for adaptation, resilience, and development, to help countries who most vulnerable to climate change, but that are not major contributors to it?" One answer is sustainable finance. Sustainability-labeled debt can provide opportunities to drive and scale financial flows in emerging markets. Though issuing a green bond doesn't eliminate the liquidity, currency or country risk facing some emerging market nations, hopefully more funds can be leveraged under the sustainable finance umbrella to drive additional financing and a just climate transition for these countries.   Growing Regulatory Focus on Scope 3 Reporting  Regulators globally continue to push for disclosure and reporting of scope 3 emissions. In October 2022, the International Sustainability Standards Board (ISSB) voted unanimously to require companies to disclose scope 1, scope 2 and scope 3 greenhouse gas emissions, and will develop relief provisions to help companies apply the scope 3 requirements.2 This follows the U.S. Securities and Exchange Commission's proposal for climate disclosure published earlier this year which includes reporting on Scope 3 for large U.S. companies.   0:00:51  Market overview  0:01:24  Use of proceed rebound  0:02:15  CBI conference outcomes  0:03:22  Green bond issuances pass US$2 trillion globally  0:04:08  FCA report on fund labeling  0:04:58  CBI reports and consultations  0:05:36  Scope 3 reporting in the news  0:06:21  Sustainable finance for emerging markets  0:07:01  Funding instruments to support conservation - blended finance and debt to nature swaps  0:09:00  Green and social loans tied to banks SLL pools  0:09:46  SLB and SLL overview  0:14:04  Audience questions  0:19:47  Green bonds and loans overview  0:25:40  Social bonds and loans overview  0:29:05  Labeled products, transition bonds and regulatory updates  Links to Select Resources Environmental Finance – World Bank Warns of SLB Greenwashing Risk From 'Structural Loopholes' Environmental Finance – Climate Bonds Standard Extension to SLBs to 'Fire Integrity' Global Capital – French Agencies Struggle to Tighten Green Deals Environmental Finance – EM Financial Institution Green Bond Impact Reporting Study Published IISD - AfDB Report Assesses Feasibility of Debt-for-Nature Swaps in Africa Environmental Finance – Investors Calling on TNFD to Address Nature Restoration Environmental Finance – Inflation Reduction Act 'Could Transform Bond Market', Conference Hears Global Capital – Bonds Tied to Banks' SLL Pools Could Spread in 2023 Global Capital – Dearth of Climate Adaptation Bonds Spurs Call for New Asset Class Delano – Green Bonds Issuers Adapt to EU Taxonomy: LuxSE Climate Bonds Initiative – 101 for Policymakers Climate Bonds Initiative Hydrogen Production Criteria Sustainalytics SPOs: Uruguay's Sovereign Sustainability-Linked Bond Framework Second-Party Opinion CEMEX Sustainability-Linked Financing Framework Second-Party Opinion PT Semen Indonesia (Persero) Tbk Sustainability-Linked Finance Framework Second-Party Opinion Government of Chile Sustainability-Linked Bond Framework Second Party Opinion Japan Bank for International Cooperation Green Bond Second-Party Opinion IIFL Home Finance Limited Sustainable Finance Framework Second-Party Opinion Georgian Renewable Power Operations Green Bond Framework Second-Party Opinion Carmila Green Bond Framework Second-Party Opinion First Help Financial Social Bond Framework Second-Party Opinion    More Episodes

Episode Summary  Hosts  Nicholas Gandolfo, Director, Corporate Solutions   Sabrina Tang, Sales Associate, Sustainable Finance Solutions   Despite continued pressure on global financial markets, our hosts Nick and Sabrina highlight some bright spots within sustainable finance. From the array of green bond transactions coming to market in recent months, to sovereigns exploring sustainable finance opportunities to fund biodiversity, marine conservation and social programs, the sustainable finance market continues to push against market headwinds.   Biodiversity Rising on Sustainable Finance and Corporate Agendas  With COP27 ending and the UN Conference on Biodiversity (COP15) coming up in December, the issue of biodiversity continues to resonate among sustainable finance market participants. Companies are starting to focus more on biodiversity issues and their impact, and the Taskforce on Nature-related Financial Disclosures has also updated its beta framework. Sovereigns, such as Uruguay, are also joining the movement by funding efforts around biodiversity using sustainability-linked bonds.   Use of Proceed Instruments Increase as Sustainability-Linked Instruments Faces Scrutiny Contracting global financial markets has put pressure on the bond market. However, Nick does note a slight uptick in the number and variety of labeled use of proceed bond issuances in recent months relative to sustainability-linked bond issuances. This could be due, in part, to the growing scrutiny of linked bond instruments. Should they be more nuanced? Do the benefits of the pricing dynamics outweigh the penalties for not meeting targets? These are all valid questions being raised about these financing instruments that have seen tremendous growth over the last few years. It remains to be seen whether these questions translate into new norms for the market.   Key Moments 0:00:57 Market overview 0:01:29 GSSS market pressures 0:02:40 Biodiversity and sovereign SLBs 0:03:51 Continuing scrutiny of SLBs 0:04:25 FCA consultation paper 0:05:15 Banks explore funding pools of SLLs 0:05:45 Singapore banks commitments to Net Zero 0:06:32 New reports from Climate Bonds Initiative 0:07:55 SLB and SLL overview 0:13:39 Audience questions 0:17:56 Green bonds overview 0:20:47 Green loans overview 0:22:25 Social bonds and loans overview 0:23:46 Labeled products overview 0:24:50 Transition bonds overview 0:26:41 Regulatory and country updates List of Select Resources Investment Magazine: Responsible Investment Hits Record in 2021   Investment Week: S&P Global Ratings Downgrades GSSSB Forecast by 16%  Environmental Finance: Sustainable Bonds Take Record Market Share Environmental Finance: NatWest: Biodiversity-linked Sovereign SLBs Could Be 'Powerful' Environmental Finance: HSBC: COP15 Will See More Green Bond Focus on Biodiversity  Environmental Finance: SLB Step-ups Have Almost No Correlation With Credit Quality  Environmental Finance: Sovereign Sustainability-linked Debt Initiative Launched  Financial Conduct Authority (FCA): Sustainability Disclosure Requirements and Investment Labels  Finance Asia: Social Risks Can Be Credit Risks: Evaluating the 'S' in ESG  Finextra: Greenwashing is a Systemic Problem at UK Banks  Climate Bonds Initiative: New Social and Sustainability Bond Database: Enhanced Screening Capabilities for Full GSS+ Market  Sustainalytics SPOs: Uruguay's Sovereign Sustainability-Linked Bond Framework Second-Party Opinion  More Episodes

In this episode, Julie M. Vose, MD, MBA, and Matthew S. Davids, MD, MMSc, discuss their choices of recent important trials presented at the Pan Pacific Lymphoma Conference 2022 evaluating the use of BTK inhibitors in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). The discussion includes analyses of: BRUIN (CLL/small lymphocytic lymphoma [SLL]): phase I/II study of pirtobrutinib for previously treated CLL (including previous BTK inhibitor)SEQUOIA: phase III study evaluating cohort 1 of zanubrutinib vs bendamustine/rituximab in untreated CLL/SLL without del(17p)MAJIC: phase III trial in progress of acalabrutinib + venetoclax vs venetoclax + obinutuzumab in previously untreated CLLBRUIN (MCL): phase I/II study of pirtobrutinib for previously treated MCL (including previous BTK inhibitor)BRUIN MCL-321: phase III trial in progress of pirtobrutinib vs investigator's choice acalabrutinib, ibrutinib, or zanubrutinib in previously treated, BTK inhibitor–naive MCLBRIDGE: series case report from phase II study evaluating zanubrutinib-based induction and maintenance in young patients with MCLPresenters: Julie M. Vose, MD, MBAChief, Division of Oncology and HematologyNeumann M. and Mildred E. Harris ProfessorDepartment of Internal MedicineUniversity of Nebraska Medical CenterOmaha, NebraskaMatthew S. Davids, MD, MMScAssociate Professor of MedicineHarvard Medical SchoolDirector of Clinical ResearchDivision of LymphomaDana-Farber Cancer InstituteBoston, MassachusettsLink to full program:https://bit.ly/3OQ6634

I am excited to welcome you to Episode #100 of SEASON 10 of 'Sharing Life Lessons'. A podcast that brings you stories from around the world to have fun with and to learn from because stories inspire, stories teach, and stories heal! We are one spirit; one soul; one world; and together we are creating a library of stories and life lessons. This is an episode of celebrations, of gratitude, of paying my respects to those who inspired me physically and in spirit. Gratitude also to you my listeners in all 32 countries, to the many monthly subscribers who funded the creation and enhancements to SLL and to all the guests for their wisdom and their time. You made this experience an inspirational one for the listeners and for me. Thank you for being part of Sharing Life Lesson's village. Sharing Life Lessons has expanded to YouTube. Please click the link below and subscribe. Also click on the bell to be notified of upcoming Volume 2 episodes. https://youtube.com/channel/UCj9tq1TlyMj79sSxITvzdMw Also, please follow the podcast Facebook page for notifications of upcoming Volume 2 episodes: Sharing Life Lessons | Facebook Email: Sharinglifelessons101@gmail.com I will bring you the 101st episode of Sharing Life Lessons as soon as I am guided by my intuition of its form and timing. Until then, with warmth, love, and gratitude - 'be happy, be safe and be blessed'. Podcast links: YouTube channel: https://youtube.com/channel/UCj9tq1TlyMj79sSxITvzdMw Apple Podcast: https://podcasts.apple.com/us/podcast/sharing-life-lessons/id1495248815?uo=4 Spotify: https://open.spotify.com/show/1EZMzRw1cWMyvSiyeeyTRdD --- Support this podcast: https://anchor.fm/sharinglifelessons/support

In this episode, Othman Al-Sawaf, MD, and Lydia Scarfò, MD, discuss key trials presented at EHA 2022 evaluating the use of BTK inhibitors in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). The discussion includes analyses of: GAIA/CLL13: phase III trial of time-limited venetoclax + obinutuzumab ± ibrutinib vs chemoimmunotherapy as first-line therapy for CLLFLAIR: randomized, adaptive-design phase III trial with data reported from ibrutinib + venetoclax and ibrutinib arm; includes measurable residual disease–defined therapy durationBRUIN: phase I/II study of pirtobrutinib for previously treated CLL (including previous BTK inhibitor)SHINE: phase III study of ibrutinib with bendamustine + rituximab and rituximab maintenance in older patients with MCLPresenters:Othman Al-Sawaf, MDFaculty of MedicineUniversity Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, GermanyVisiting ScientistThe Francis Crick InstituteUCL Cancer Institute, University College London London, United KingdomLydia Scarfò, MDLaboratory of B-Cell Neoplasia, Division of Experimental OncologyStrategic Research Program on CLLUniversità Vita Salute San Raffaele and IRCCS Ospedale San RaffaeleMilano, ItalyLink to full program:https://bit.ly/3OQ6634

In the second of two episodes on Netflix's Love is Blind, we continue our discussion with June and Lauren on dating reality television. We get into the gendered expectations around love and sex; why you should never feel guilty about enjoying reality shows; and our guests' favorite matchmaking show of all time, Are You the One? You can find Lauren and June's new show, Under Review, where ever you get your podcasts. (But here's a link to their Spotify page: https://open.spotify.com/show/1H32AGeE1ZQeRSNfy3AATI?si=422e16fdf7bf4e8e) *SLL will be on hiatus through September 2022* Don't forget to subscribe to Sex. Love. Literature! You can find us on Twitter, Instagram, and Facebook @SexLoveLit. Lit discussed this episode includes: Love Is Blind, The Bachelor, The Bachelorette, Mr. Sunshine (Kdrama), Are You The One?, A Shot at Love with Tila Tequila, Iron Chef, Nailed It, Survivor, and more~ The SLL Theme music is “Pluck It Up” by Dan Henig. “What's Sparking Joy” BGM is Candy-Coloured Sky by Catmosphere | https://soundcloud.com/ctmsphr; Released by Paper Crane Collective; Music promoted by https://www.free-stock-music.com; Creative Commons Attribution 3.0 Unported License; https://creativecommons.org/licenses/by/3.0/deed.en_US

“There will be a decentralized multiplicity of new political arrangements and subdivisions, from chaotic black holes to well-ordered enclaves. The success of the latter will be due to the freedom they embrace, the individual rights they protect, and their ability to defend their enclaves. New industries, technologies, modes of commerce, and ways of life will emerge. This will be the true great reset, not the Klaus Schwab version, which only recycles failed concepts of centralized power and collective subjugation on a larger scale.” This Is Your Last Chance with Robert Gore Robert is a writer, investor, attorney, and former bond trader. His website is straightlinelogic, and his most recent novel is The Golden Pinnacle, available on Amazon, Kindle, and Nook. He is also a regular columnist for thesavvystreet.com. A cabal of politicians, governments, courts, medical authorities, pharmaceutical companies, multinational agencies, the mainstream media, academics, and foundations, particularly the World Economic Forum, have concocted responses to a virus and its variants that have robbed the people of rightful liberties, are a mechanism for the imposition of global totalitarianism, and have amplified rather than reduced the virus's dangers, inflicting severe injury and death that will last years, perhaps decades, and afflict millions, if not billions, of victims (See “The Means Are The End,” Robert Gore, SLL, November 13, 2021). Website:  This Is Your Last Chance with Robert Gore Part 1 This Is Your Last Chance, Part 2 Great reset will fail, economic collapse, hope for humanity, Robert Gore, political change, social upheaval, a new day, imposition of global totalitarianism

Join us as we speak with Donnie Hill, a chronic lymphocytic leukemia (CLL) / small cell lymphocytic lymphoma (SLL) patient… The post Patient-Doctor Perspectives: Shared Decision Making appeared first on The Bloodline with LLS.

Join us as we speak with Donnie Hill, a chronic lymphocytic leukemia (CLL) / small cell lymphocytic lymphoma (SLL) patient… The post Patient-Doctor Perspectives: Shared Decision Making first appeared on The Bloodline with LLS.

HAPPY NEW YEAR TO ALL MY LISTENERS! I am delighted to welcome you to Episode #84 of SEASON 9 (the first episode of 2022) of 'Sharing Life Lessons'. A podcast that brings you stories from around the world to have fun with and to learn from because stories inspire, stories teach, and stories heal! We are one spirit; one soul; one world; and together we are creating a library of stories and life lessons. Sharing Life Lessons has expanded to YouTube. Please click the link below and subscribe. Also click on the bell to be notified of all new episodes. https://youtube.com/channel/UCj9tq1TlyMj79sSxITvzdMw To support the creation of this podcast please go to https://anchor.fm/sharinglifelessons and click on the support button with the dollar sign to sign up for a monthly subscription for an amount of your choice. This will enable me to continue to bring to you an enhanced season 9. The target audience for this episode is EVERYONE For this episode, I am not bringing you a guest because I want to take the time in this first episode of 2022 to set the tone for what to expect of SLL in this new year, in this new beginning. Links for Sharing Life Lessons and for Hamidah: Facebook page: Sharing Life Lessons | Facebook Instagram handle: @sharinglifelessons YouTube channel: https://youtube.com/channel/UCj9tq1TlyMj79sSxITvzdMw Apple Podcast: https://podcasts.apple.com/us/podcast/sharing-life-lessons/id1495248815?uo=4 Spotify: https://open.spotify.com/show/1EZMzRw1cWMyvSiyeeyTRdD These are the Key Takeaways from this episode: 1. Let us end with gratitude and begin with hope. 2. KNOW and BELIEVE that the end is great, regardless of the events occurring in your life. If you believe that you will manifest what you desire, then you will manifest it. 3. Let's be deliberate in everything we do and know that we always have a choice