Podcasts about morsch

Morsche, Moin, Morsché – macht eure Äuglein auf, eine neue Woche bricht an: Spaß, Spannung und Spiritualität steht auf dem Stundenplan. Proseccolaune lädt euch ein zu einem gemütlichen Softstart. Ohren auf, Laune rein. Best Wishes Chris Marek Stenger Du möchtest mehr über unsere Werbepartner erfahren? Hier findest du alle Infos & Rabatte: https://linktr.ee/proseccolaune

A father-son duo bringing medical relief to communities far and wide joins Joel Goldberg. Graham Morsch is the President and CEO of Docs Who Care, the healthcare agency redefining rural care. Graham's official tenure may have begun in 2015, but its mission has been shaping his life for decades. Dr. Gary Morsch is the esteemed humanitarian, founder of Docs Who Care ,and Executive Chairman of the Global Care Force. Together, they harnessed the power service in their mission to make a difference. Unlocking more than excellence in care, but a positive impact that ripples around the world.Website: https://docswhocare.com/ Instagram: https://www.instagram.com/docswhocare/reels/?__d=1%2F Twitter: https://x.com/docswhocare Facebook: https://www.facebook.com/docswhocare/YouTube Channel: https://youtu.be/yXzciYu2WJM

João Morsch - 06/10/2024 by Rádio Gaúcha

Nahe Dran vom 01.08.2024 - Stefan-Morsch-Stiftung by Antenne Bad Kreuznach / Idar-Oberstein

The Greg and Dan Show with special guest Lee Hall talk to writer Mike Morsch about the backstory of the hit song “Dancing in the Moonlight” by King Harvest. After noticing the resurgence of the song, Greg asked Morsch to join the show for a conversation on the horrific events that led to a joyous and uplifting song.  Visit vinyldialogues.com for more information.See omnystudio.com/listener for privacy information.

The key ingredient of the success of The Outdated Wrestling Hour With Bob Smith (the former managing editor of Pro Wrestling Illustrated and a longtime wrestling writer) is its main objective: To remember and pay tribute to the wrestling stars and territories of the past. On this special edition, journalist (and at one point, an actual wrestling reporter) Mike Morsch takes a look back at his in-person memories of Central States Wrestling - as well as great stars such as Harley Race, Mike George, Rufus R. "Freight Train" Jones, Roger Kirby, Dick The Bruiser, and many more legends. And, as always, a freewheeling conversation ensues - the hallmark of one of the most entertaining wrestling nostalgia podcasts to hit apps everywhere!Support the showContact us at outdatedwrestling@gmail.com!

In der 209. Folge von „bto – beyond the obvious – der Ökonomie-Podcast mit Dr. Daniel Stelter“ beschäftigen wir uns mit der Fähigkeit Deutschlands, die Krise der Wirtschaft zu bewältigen. Bundeskanzler Olaf Scholz und Wirtschaftsminister Robert Habeck haben die Widerstandsfähigkeit der hiesigen Wirtschaft erneut beschworen und einen neuen Aufschwung in Aussicht gestellt. Nur zu gerne wollen die Bürger das glauben. Aber ist es auch realistisch? Hat die Regierung das Ausmaß der Herausforderungen in vollem Umfang erfasst? Dazu im Gespräch: der Wirtschaftshistoriker Dr. Werner Plumpe, emeritierter Professor der Goethe-Universität Frankfurt am Main.Täglich neue Analysen, Kommentare und Einschätzungen zur Wirtschafts- und Finanzlage finden Sie unter think-bto.com.Sie erreichen die Redaktion unter podcast@think-bto.com. Wir freuen uns über Ihre Meinungen, Anregungen und Kritik.ShownotesHandelsblattEin exklusives Angebot für alle “bto - beyond the obvious 2.0 - featured by Handelsblatt”-Hörer*innen: Testen Sie Handelsblatt Premium 4 Wochen lang für 1 Euro und bleiben Sie zur aktuellen Wirtschafts- und Finanzlage informiert. Mehr erfahren Sie unter: https://handelsblatt.com/mehrperspektiven Urban Sports ClubDas vielfältigste Sport- und Wellnessangebot in Europa - in nur einer Mitgliedschaft! Entdecke über 50 Sportarten, entspanne beim Wellness und werde aktiv, wann und wo du willst: indoor, outdoor und online. Mit Firmenfitness gibt es ein spezielles Angebot für Arbeitnehmende und Arbeitgebende mit Win-Win-Vorteilen für beide! Sprich deinen Arbeitgeber auf Firmenfitness von Urban Sports Club an! Mehr Informationen gibt es hier: FirmenfitnessAveaAvea ist eine Schweizer Marke und hat sich auf die Entwicklung innovativer Nahrungsergänzungsmittel für Langlebigkeit und optimale Gesundheit spezialisiert. Ziel von Avea ist es, den Alterungsprozess zu verlangsamen und das allgemeine Wohlbefinden zu fördern. Das beliebteste Produkt, das Vitality Bundle, stärkt und reguliert die NAD+-Produktion, fördert jugendliche Vitalität und unterstützt die langfristige Zellgesundheit, um Alterungsprozesse zu verlangsamen und Energie, kognitive Funktionen und den Stoffwechsel zu verbessern. Hosted on Acast. See acast.com/privacy for more information.

Alex Morsch of Peak Realty is a Commercial Broker and Investor with vast experience in repositioning assets in West Town.  Alex starts by discussing the grind of being a leasing agent and transitioning to brokering real estate! He lays out his experience walking 100 buildings prior to making his first purchase and the valuable lessons gained through that process. Alex breaks down how his “nose to the ground” approach to investment property acquisition has allowed him to add immense value to his clients and succeed as a broker. He also drops wisdom on house hacking, the West Town neighborhood, and creating opportunities in a tight inventory market. Alex closes with a bullish 5 year outlook on Chicago Real Estate! If you enjoy today's episode, please leave us a review and share with someone who may also find value in this content! Connect with Mark and Tom: StraightUpChicagoInvestor.com Email the Show: StraightUpChicagoInvestor@gmail.com Guests: Alex Morsch, Peak Realty Link: Alex's Instagram Link: Rich Anselmo (Network Referral) ----------------- Guest Questions 02:24 Housing Provider Tip: Check the faucet aerator when troubleshooting low water pressure! 03:56 Intro to our guest, Alex Morsch! 07:33 The grind of being a leasing agent. 12:52 Transitioning from leasing to a commercial broker! 16:30 Walking properties to gain experience. 26:38 Alex's first investment! 37:57 The reality of House Hacking. 42:25 Breaking down the West Town neighborhood! 49:10 Finding deals and creating opportunities. 54:27 Alex's 5 year outlook on Chicago Real Estate! 55:18 What is Alex's competitive advantage? 55:35 One piece of advice for new investors. 55:53 What do you do for fun? 56:12 Good book, podcast, or self development activity that you would recommend? 57:05 Local Network Recommendation? 57:35 How can the listeners learn more about you and provide value to you? ----------------- Production House: Flint Stone Media Copyright of Straight Up Chicago Investor 2023.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.06.21.546009v1?rss=1 Authors: San Gil, R., Pascovici, D., Venturato, J., Brown-Wright, H., Mehta, P., Madrid San Martin, L., Wu, J., Chui, Y. K., Bademosi, A., Swaminathan, S., Luan, W., Berning, B. A., Wright, A. L., Keating, S. S., Lee, A., Morsch, M., Chung, R. S., Lisowski, L., Mirzaei, M., Walker, A. K. Abstract: Understanding the mechanisms that drive TDP-43 pathology is integral to combating neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). To address this, we sought to determine the timeline of proteomic alterations across disease course in TDP-43 proteinopathy. Using longitudinal quantitative proteomics analysis of cortex samples from the cytoplasmic TDP-43 rNLS8 mouse model of ALS and FTLD, we identified several distinct protein subsets characterized by temporal alterations in protein abundance across diverse biological pathways, including protein folding, intracellular transport, myelination, and neuronal synaptic function. Remarkably, neurons in the rNLS8 cortex elicited a transitory response primarily comprising protein-folding factors prior to and in the earliest stages of disease progression. This response included increased levels of DnaJ homolog subfamily B member 5, DNAJB5, and proof-of-concept studies showed that DNAJB5 over-expression decreased TDP-43 aggregation in cell and cortical neuron cultures. Conversely, knockout of Dnajb5 exacerbated motor impairments caused by AAV-mediated cytoplasmic TDP-43 expression in the brains and spinal cords of mice. Lastly, the late disease proteomic signatures of rNLS8 mouse cortex strongly correlated with changes in human autopsy-derived TDP-43 proteinopathy tissues, indicating commonality of disease processes. Together, these findings reveal molecular mechanisms that regulate protein levels through distinct stages of ALS and FTLD progression, and suggest that protein folding factors that combat cytoplasmic TDP-43 protein aggregation could be protective in disease. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Nilton Schutz entrevista Fred Morsch, documentarista, pesquisador de fenômenos anômalos e apresentador da série "De Carona com os Óvnis".

Invitada: Camila Morsch British Council ofrece becas en Reino Unido para mujeres que se desarrollen en las áreas de ciencia, tecnología, ingeniería y matemáticas. La beca incluye tasas de matrícula, espendio mensual, gastos de viaje, tasas de visado y gastos médicos. Esta prestigiosa beca permitirá a más de 100 mujeres obtener un título de posgrado en Reino Unido, dando la oportunidad de seguir desarrollando sus carreras en materias STEM. Conducción: Sofía Solorzano y Juan Pablo Balcells. Producción: Armando Tiburcio. Sistema Jalisciense de Radio y Televisión. Escucha la música del día dando clic aquí Visita: www.jaliscoradio.com Edición: Lupita Jiménez Fecha: 08 de Marzo 2023

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Im neuen Stück «Morsch» der Theatergesellschaft Appenzell dreht sich alles um das Alter und das Älterwerden - und wie eine alteingesessene Wohngemeinschaft die Alte Bleiche retten will. Weitere Themen:  * Das Strandbad Hard ist wegen Keimen gesperrt * Die Gemeinde Glarus Nord will Wasser sparen und stellt erste Brunnen ab * Ostschweizer Schwinger gehören zu den Favoriten im Kampf um den Königstitel

Tivemos um super batepapo com o Fred Morsch e o Arthur Neto, contamos os bastidores da série De Carona com os OVNIs e histórias inéditas. Esperamos por todos vocês no evento na Pousada Beleza da Serra nos dias 24 e 25/06. Link com informações do evento: https://www.instagram.com/p/CdD2UNtMRxU/?igshid=YmMyMTA2M2Y= Canal do Fred Morsch https://youtube.com/c/FredMorsch Sigam também o Podcast Cabana do Mistério no seu agregador de podcast favorito. https://linktr.ee/cabanadomisterio Spotify https://open.spotify.com/show/3tjmAkZsMHyngc2aWLrzIF?si=bvfVYa5aRUiy3w7pLmSIpw&utm_source=copy-link _______*_*_______ Seja um apoidor deste podcast: https://apoia.se/ufologiaeideias Sua contribuição será de suma importância para a melhoria da qualidade sonora deste podcast, mais detalhes da campanha, clique no link acima. Ou se preferir fazer uma humilde contribuição espontânea via PIX, código celular (11) 9 8730 2933 Se o seu player de podcast permitir, se inscreva, ative o sininho de notificação, avalie com cinco estrelas e favorite. _______*_*______ Todos nossos links: https://linktr.ee/ufologia_e_ideias _______*_*______ Aprecie a Loja Flutuante Https://montink.com/loja-flutuante/colab-ufologia-e-ideias-rey0b ou a camisa nova https://lojaflutuante.com.br/colab-ufologia-e-ideias-2-myzzz _______*_*______ Convite do Canal do Telegram do Podcast Ufologia e Ideias https://t.me/ufologiaeideias _______*_*_______ Siga nosso Instagram: https://instagram.com/ufologiaeideias?utm_medium=copy_link _______*_*_______

Após dois anos sem edição, em virtude da pandemia, a maior feira agropecuária do Brasil voltada à agricultura familiar retoma às atividades. O Sicredi que, desde 2004, é um dos principais patrocinadores do evento, estará presente e com novo espaço diferenciado para receber os visitantes da 20ª Expoagro Afubra, que acontece de 23 a 26 de março, no Parque de Exposições, em Rincão Del Rey, Rio Pardo. A Casa Sicredi, apresentada para lideranças, autoridades e imprensa, na noite desta segunda-feira, 21, foi viabilizada de forma cooperativa pela Sicredi Vale do Rio Pardo, Centro Serra e Centro Leste. A construção da Casa Sicredi marca de forma definitiva a presença do cooperativismo de crédito na Expoagro Afubra. “Temos orgulho de fazer parte da história da Expoagro desde o início, que ao longo dos anos se transformou na mais importante feira do Brasil voltada à agricultura familiar. Queremos que este espaço seja uma extensão e uma expressão do Sistema Sicredi, que acredita no potencial da feira em seu propósito de difusão da diversificação produtiva e tecnológica para a agricultura familiar, viabilizado por intermédio das nossas três cooperativas – Vale do Rio Pardo, Centro Serra e Centro Leste”, salientou o presidente da Sicredi Vale do Rio Pardo, Heitor Álvaro Petry. Pensada para ser o local permanente do Sicredi na Expoagro, a Casa estará voltada para acolher os associados e visitantes, bem como para a realização de eventos e atividades de forma integrada com a coordenação da feira, seja de conhecimento técnico, de crédito ou de parcerias e negócios. “A Expoagro é referência para o agronegócio. E a Casa Sicredi será o espaço para bem receber nossos associados, contribuindo ainda mais para o seu desenvolvimento”, completou o presidente da Sicredi Centro Leste RS, Paulo Alex Falcão. Já o presidente da Sicredi Centro Serra, Egídio Morsch, destacou a ligação histórica do Sicredi com a Expoagro e com o agronegócio. “Uma das formas de demonstrar o compromisso desta ligação e sua perenidade se dá através da instalação da Casa Sicredi dentro do Parque da Expoagro, o que oportunizará melhor receber nossos associados, além de estreitar relacionamentos com demais empresas e entidades vinculadas à feira”, frisou. Com 218 metros quadrados de área construída, a Casa Sicredi está localizada no Lote 267 dentro do Parque da Expoagro Afubra. O prédio conta com recepção, auditório, salas de reuniões, cozinha e banheiros. O projeto é assinado pelo escritório Thomas Horn Arquitetura e Planejamento. Durante a feira de 2022, o local vai abrigar uma diversificada programação relacionada ao desenvolvimento do agronegócio regional. A ideia é que, em outras épocas do ano, o local também possa sediar encontros liderados ou apoiados pela Sicredi com foco na qualificação dos associados ou das comunidades onde atua.

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Compacto de entrevista com a abordagem de temas pertinentes à comunidade do Vale do Rio Pardo e Taquari. A cada edição um tema relevante ou algum assunto específico de ampla repercussão

Deze aflevering van de Product Owner podcast spreken we met Marieke, een ware digitale duizendpoot. Haar ervaring rijkt van een eigen online shop tot marketeer en van digitaal strateeg tot product owner. Ze is een ware specialist als het aankomt op ideation en design thinking, met een passie voor klantcentrale productontwikkeling. Vandaag de dag werkt ze onder andere als innovation lead voor de Rotterdamse UX experts van Online Department. In deze aflevering gaan we met Marieke in gesprek om meer te ontdekken over haar manier van klantcentrale productontwikkeling.   LinkedIn Marieke Morsch Website Online Department   LinkedIn Productowner.nl Website Productowner.nl

OCO? Das sind 2 mal O plus C! Der Firmenname ist frei abgeleitet von CO2, Kohlensäure. Für den Familienbetrieb aus Schwanau-Allmannsweier ist das zu einer echten Erfolgsformel geworden, inzwischen mit über 30 Jahren Erfahrung. Hier steht man füreinander ein, alle arbeiten mit. Auf ein paar Umwegen hat auch Geschäftsführer Marco Siefert den Weg ins elterliche Unternehmen gefunden. Im #Vobatalk erfahren wir, dass es recht locker zugeht bei den Sieferts, es wird oft und gerne gelacht. Mit dem Heliumgas, dass man hier natürlich auch bekommt, hat das nichts zu tun. Die gute Stimmung überträgt sich auch auf Firmenkundenberater Torsten Morsch. Er kennt die Familie schon lange und die Zusammenarbeit macht ihm richtig Spaß! Bei OCO geht's also um Gas, sämtliche Gase in verschiedensten Reinheitsgraden. Abgefüllt und verkauft wird in den handelsüblichen Flaschengrößen. Dazu gehören die kleineren Einheiten für den Privatgebrauch, z. B. fürs Grillen oder Campen. Aber auch für die großen Anbieter und Marken ist das OCO ein verlässlicher Dienstleister. Noch recht neu ist das Thema Bio-Kohlensäure, ein weiteres Standbein, bei dem Marco Siefert viel Potenzial sieht. Außerdem sprudelt in Schwanau auch die Eigenmarke sodaO, eine echte Alternative zum Marktführer. Alle Beteiligten haben richtig Gas gegeben, um die Finanzierung der neuen Abfüllanlage mit den attraktiven Zuschüssen der öffentlichen Hand zu realisieren. Firmenbankchef Bernd Schwendemann und Prokurist Torsten Morsch raten Unternehmern schon in der Planungsphase nach Fördermitteln zu fragen. Es gibt so viele Fördertöpfe und Zuschüsse, da sollte man nichts verschenken. Übrigens: Bei uns im Podcast #Vobatalk gibt es noch viele weitere spannende Unternehmen mit tollen Menschen und ihren Geschichten. Reinhören lohnt sich: bei uns im Web, bei YouTube und allen bekannten Podcast-Kanälen.

Ouça um trecho do romance “Van Ella Citron”, de Bruna Sofia Morsch, lançado em 2017, pela editora Micronotas. Ficha técnica: Indicação: Juliana Ben (Sesc Palhoça) Roteiro: Diego Elias (Sesc Balneário Camboriú) Leitura: Marina Gelowate Fernandez (Sesc Mafra) Edição: Marina Gelowate Fernandez (Sesc Mafra) Trilha sonora: "Oceano", de Cleyton Eduardo Souza (Sesc Itajaí) e Peter Allan Ramos (Sesc Balneário Camboriú)

Nach den sechs Monaten Take-away freuen sich Sternekoch Daniel Fehrenbacher und sein Team vom renommierten Hotel-Restaurant Adler in Lahr-Reichenbach, ihre Gäste wieder persönlich zu verwöhnen. Ein besonderer Lichtblick ist die neue Küche, die mit Fördermitteln aus der „Innovationsfinanzierung 4.0“ und Zuschüssen realisiert werden konnte. Damit konnte sich der Sternekoch auch einen persönlichen Wunsch erfüllen und einen so genannten „Cheftable“ integrieren. Was es damit Besonderes auf sich hat und wie wir als Genießer davon profitieren können, verrät uns der Küchenchef direkt im #VOBATALK. Wir erfahren auch, was Firmenkundenberater Torsten Morsch und Vorstand Reiner Richter antreibt und wollen natürlich wissen, ob sie zuhause auch mal den Kochlöffel schwingen? Wer sich als kleines „Fördertrüffelschweinchen“ etabliert hat, aber auch mal einen Hotdog probiert oder sich von Kochbüchern und chilliger Musik inspirieren lässt, erfahren wir gleich hier im Podcast. In den nächsten Folgen vom #VOBATALK geht´s weiter mit spannenden Geschichten und tollen Menschen. Reinhören lohnt sich, überall da, wo es Podcast gibt, bei YouTube und im Web. Vielen Dank fürs Abonnieren, Liken und Teilen.

Most procurement organizations want to increase their internal influence and improve their working relationship with other functions - after all, that seems like the straightest path to opportunity and recognition. So what happens when a procurement team succeeds? What doors are opened and what additional efforts have to be launched? Is increased influence all it is cracked up to be or is it simply a ‘grass is greener' type of situation? We find out in this conversation. In this episode of The Sourcing Hero podcast, Host Kelly Barner is joined by Mike Morsch. Mike is the VP of Global Procurement and Supply Chain for CDK Global, a leading provider of integrated data and technology solutions to the automotive, heavy truck, recreation, and heavy equipment industries. But that's not all - he also has responsibility for Real Estate, Repair operations and has led business transformation and M&A transactions. In this conversation, Mike shares his perspective on: The difference between a leader's ‘day job' and their ‘night job' and how each contributed to their ability to succeed His team's working relationship with finance - including how it was established and the investments he makes on a regular basis to keep a productive dynamic in place How we should consider and aim to leverage technology as procurement takes on more complex challenges in pursuit of business objectives

U.S. Air Force Command Chief Master Sgt. Mark Legvold, 133rd Airlift Wing, interviews U.S. Air Force 1st Lt. Katherine Morsch, 133rd Airlift Wing, in St. Paul, Minn., Mar. 3, 2021. Morsch talks about her job as a Victim’s Advocate at Camp Ripley and going to Ghana for the Peace Corps. (U.S. Air National Guard podcast by 133rd Airlift Wing Public Affairs)

Nur morsche Bäume knicken bei Gegenwind ein... Bist du Morsch? Aktuell bin ich nicht so gut drauf und meine Erfahrungen teile ich heute in dieser Podcastfolge mit euch. Vielleicht kann der ein oder andere etwas mitnehmen :)

1984 erkrankte der 16-jährige Stefan-Morsch aus Rheinland-Pfalz an Leukämie. Seine Eltern gründeten 1986 die nach ihm benannte Stiftung mit dem Ziel, eine Stammzellenspenderdatei aufzubauen, um anderen bei ihrem Kampf gegen die Krankheit zu helfen.

Der 16jährige Stefan Morsch aus Rheinland-Pfalz erkrankte 1984 an Leukämie. Da sich in der Familie kein passender Spender fand, gab es nur eine Chance: Als erster Europäer erhält Stefan fremde Stammzellen. Trotzdem stirbt er an einer Lungenentzündung. Nach Stefans Tod wollen seine Eltern die Idee ihres Sohnes umsetzen: Ein Computerprogramm als Basis für eine Stammzellspenderdatei, die es weltweit noch nicht gab und gründen somit 1986 die Stefan-Morsch-Stiftung. Autorin: Martina Meißner

Es war der große und letzte Wunsch des 16jährigen Stefan Morsch aus Rheinland-Pfalz: Hilfe für Leukämiepatienten bei der Suche nach einem Spender. Diesen Wunsch befolgten seine Eltern 1986. Mit der Gründung der Stefan-Morsch-Stiftung am 27. Januar 1986 und der ersten Stammzellenspenderdatei.

Nessa semana, Ribas e Zoucas pegam uma carona no Jipe do terráqueo, Brasileiro e mochileiro ufológico, Fred Morsch! Vamos juntos conhecer um pouco dos "hot spots" do nosso "Brasilzão" e os bastidores do primeiro documentário sobre ufologia do Brasil, De Carona com os Ovnis, do History Channel. Caso você tenha algum relato que queira compartilhar conosco, mande via áudio no Whatsapp juntamente com seu nome e cidade. +1(647) 884 3958 ou +1(647)830 0422 All audio tracks including the opening theme are under Creative Commons Licence, for more reference, check the link bellow. https://creativecommons.org/licenses/by/4.0/ === APOIA-SE === Com QUALQUER quantia acima de R$5 Reais, você estará contribuindo para o crescimento desse projeto, que ainda tem muita coisa legal para mostrar! https://apoia.se/hangar18podcast Apoia.se: https://apoia.se/hangar18podcast See omnystudio.com/listener for privacy information.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.08.330894v1?rss=1 Authors: Don, E. K., Maschirow, A., Radford, R. A. W., Scherer, N. M., Vidal-Itriago, A., Hogan, A., Maurel, C., Formella, I., Stoddart, J. J., Hall, T. E., Lee, A., Shi, B., Cole, N. J., Laird, A. S., Badrock, A. P., Chung, R. S., Morsch, M. Abstract: Amyotrophic lateral sclerosis (ALS) is a form of motor neuron disease (MND) that is characterized by the progressive loss of motor neurons within the spinal cord, brainstem and motor cortex. Although ALS clinically manifests as a heterogeneous disease, with varying disease onset and survival, a unifying feature is the presence of ubiquitinated cytoplasmic protein inclusion aggregates containing TDP-43. However, the precise mechanisms linking protein inclusions and aggregation to neuronal loss are currently poorly understood. Bimolecular Fluorescence Complementation (BiFC) takes advantage the association of fluorophore fragments (non-fluorescent on their own) that are attached to an aggregation prone protein of interest. Interaction of the proteins of interest allows for the fluorescent reporter protein to fold into its native state and emit a fluorescent signal. Here, we combined the power of BiFC with the advantages of the zebrafish system to validate, optimize and visualize of the formation of ALS-linked aggregates in real time in a vertebrate model. We further provide in vivo validation of the selectivity of this technique and demonstrate reduced spontaneous self-assembly of the non-fluorescent fragments in vivo by introducing a fluorophore mutation. Additionally, we report preliminary findings on the dynamic aggregation of the ALS-linked hallmark proteins Fus and TDP-43 in their corresponding nuclear and cytoplasmic compartments using BiFC. Overall, our data demonstrates the suitability of this BiFC approach to study and characterize ALS-linked aggregate formation in vivo. Importantly, the same principle can be applied in the context of other neurodegenerative diseases and has therefore critical implications to advance our understanding of pathologies that underlie aberrant protein aggregation. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.22.309062v1?rss=1 Authors: Hogan, A. L., Grima, N., Fifita, J. A., McCann, E. P., Heng, B., Chan Moi Fat, S., Maharjan, R., Cain, A. K., Henden, L., Zang, K. Y., Zhao, Q., Zhang, Z.-H., Wright, A., Wu, S., Morsch, M., Yang, S., Williams, K. L., Blair, I. P. Abstract: Background: Splicing factor proline and glutamine rich (SFPQ, also known as polypyrimidine tract-binding protein-associated-splicing factor, PSF) is a RNA-DNA binding protein with roles in key cellular pathways such as DNA transcription and repair, RNA processing and paraspeckle formation. Dysregulation of SFPQ is emerging as a common pathological feature of multiple neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Increased retention of SFPQ intron nine and nuclear loss of the protein have been linked to multiple genetic subtypes of ALS. Consequently, SFPQ dysregulation has been hypothesised to be a common pathological feature of this highly heterogeneous disease. Methods: This study provides a comprehensive assessment of SFPQ pathology in large ALS patient cohorts. SFPQ gene expression and intron nine retention were examined in multiple neuroanatomical regions and blood from ALS patients and control individuals using RNA sequencing (RNA-Seq) and quantitative PCR (RT-qPCR). SFPQ protein levels were assessed by immunoblotting of patient and control motor cortex and SFPQ expression pattern was examined by immunofluorescent staining of patient and control spinal cord sections. Finally, whole-genome sequencing data from a large cohort of sporadic ALS patients was analysed for genetic variation in SFPQ. Results: SFPQ intron nine retention was significantly increased in ALS patient motor cortex. Total SFPQ mRNA expression was significantly downregulated in ALS patient motor cortex but not ALS patient blood, indicating tissue specific SFPQ dysregulation. At the protein level, nuclear expression of SFPQ in both control and patient spinal motor neurons was highly variable and nuclear depletion of SFPQ was not a consistent feature in our ALS cohort. However, we did observe SFPQ-positive cytoplasmic ubiquitinated protein aggregates in ALS spinal motor neurons. In addition, our genetic screen of ALS patients identified two novel, and two rare sequence variants in SFPQ not previously reported in ALS. Conclusions: This study shows that dysregulation of SFPQ is a feature of ALS patient central nervous system tissue. These findings confirm SFPQ pathology as a feature of ALS and indicate that investigations into the functional consequences of this pathology will provide insight into the biology of ALS. Copy rights belong to original authors. Visit the link for more info

Procurement titan Mike Morsch comes on to talk about artificial intelligence, starting out in IT, and growing to love the structure of procurement.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.30.071365v1?rss=1 Authors: Rayner, S. L., Cheng, F., Yang, S., Grima, N., Ke, Y. D., Au, C. G., Morsch, M., De Luca, A., Davidson, J. M., Molloy, M. P., Shi, B., Ittner, L. M., Blair, I., Chung, R. S., Lee, A. Abstract: Background: Previously, we identified missense mutations in CCNF that are causative of familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). CCNF encodes for the protein cyclin F, a substrate recognition component of the E3-ubiquitin ligase, SCFcyclin F. We have previously shown that mutations in CCNF cause disruptions to overall protein homeostasis; causing a build-up of ubiquitylated proteins (1) as well as defects in autophagic machinery (2). Methods: Here, we have used an unbiased proteomic screening workflow using BioID, as well as standard immunoprecipitations to identify novel interaction partners of cyclin F, identifying the interaction between cyclin F and a series of paraspeckle proteins. The homeostasis of these new cyclin F interaction partners, RBM14, NONO and SFPQ were monitored in primary neurons using immunoblotting. In addition, the homeostasis of RBM14 was compared between control and ALS/FTD patient tissue using standard IHC studies. Results: Using BioID, we found over 100 putative interaction partners of cyclin F and demonstrated that cyclin F closely associates with a number of essential paraspeckle proteins, which are stress-responsive proteins that have recently been implicated in ALS pathogenesis. We further demonstrate that the turnover of these novel binding partners are defective when cyclin F carries an ALS/FTD-causing mutation. In addition the analysis of RBM14 levels in ALS patient post-mortem tissue revealed that RBM14 levels were significantly reduced in post-mortem ALS patient motor cortex and significantly reduced in the neurons of spinal cord tissue. Conclusion: Overall, our data demonstrate that the dysregulation of paraspeckle components may be contributing factors to the molecular pathogenesis of ALS/FTD. Copy rights belong to original authors. Visit the link for more info

  At the 2019 Future of Sourcing Awards, Mike Morsch, Vice President of Global Procurement and Supply Chain at CDK Global, was inducted into the Sourcing Supernova Hall of Fame. Mike talks about what this award means to him and his career and introduces key team members who contribute to the organization's success. Learn about this $2 billion integrated IT solutions organization, its value as a global provider within the automotive retail industry and the direct impact this team has on the bottom line. Visit the Future of Sourcing Awards to learn more about Mike and meet the other 2019 award winners.  

Je vous présente ici une super belle personne, Capucine Morsch qui nous parlera de l'importance de la maîtrise de notre énergie sexuelle pour mieux réussir en tant qu'entrepreneur ! Accès au Sommet du Couple et de la Sexualité : http://sommetducoupleetdelasexualite.fr/ Sa Formation : https://capucinemorsch.systeme.io/formationgratuitehermesvideo1 Inscris toi à la formation Confiance Level UP : http://bit.ly/confiancelevelup 1 heure de coaching haute performance offert : http://bit.ly/candidature2019 Écoute sur Itunes : https://apple.co/2IWH83P Écoute sur Spotify : https://spoti.fi/2GTxv2v Écoute sur Soundcloud : Bientôt disponible Télécharge gratuitement mon cahier d'exercices de développement personnel pour entrepreneurs : https://rebrand.ly/cahierdexercices

Rhiannon Morsch is a healing guide and intuitive channel. Along her journey she has gathered expertise in a broad range of transformational healing modalities, including Depth Hypnosis, Core Shamanism, and Energy Medicine. Through the blended use of these methods along with her multi-dimensional channeling gifts, she has found her way to powerful toolbox that allows her to offer a unique and transformational healing experience in service to others. She has a private healing practice in Berkeley, CA and also works over distance with clients from all over the world.  Episode Highlights Rhiannon shares how she works as an intuitive channel working with clients to support their healing intentions. Using depth hypnosis (a synthesis of shamanic practices, energy medicine, Buddhist psychology and transpersonal psychology) she helps her clients, particularly around experiences of sexual trauma. We discuss connecting to our own ancestral lineage and spirit guides to facilitate healing work. How she came to her path as a healer after going through her own healing journey and having spiritual experiences which opened her up. She shares how depth hypnosis specifically helped her heal her own sexual trauma, which helps her know how to support others. Using soul retrieval to reclaim and heal fragmented parts of ourselves. This fragmentation is a common occurrence during a traumatic experience. The practice of facilitating Womb Space Clearing to help people on a fertility journey. She also offers online group channeling sessions, “The Knowing.”   Web links Find more at  RhiannonMorsch.com Find Rhiannon on Instagram   Join the Queer Spirit Community Facebook group to continue the conversation and stay up to date on new episodes.  And follow us on Instagram! Join our mailing list  to get news and podcast updates sent directly to you.

In the 5th episode of Wisdom on Trial, Dave speaks with with attorney Mark Morsch on the topics of life, giving back, and the importance of accountability.

Liderar em meio a constantes disrupções de modelos de negócios é um desafio em qualquer empresa. Nesta entrevista, Leandro Vieira e o professor e consultor Marco Aurélio Morsch conversam sobre o papel e a atitude dos líderes em tempos de transformação digital.

From starting his career as a software developer, Mike worked his way up through IT organizations to hone the craft of IT and created the procurement function at CDK Global from scratch. After spending years working alongside the procurement organization in previous positions, he now leads a world-class procurement team and brings his unique insight to the procurement role. Leading CDK's digital transformation and championing RPA implementation within CDK, Mike is passionate about leading the sourcing and supply chain into the next generation of technology. Mike's message is clear: CPOs need to be technology evangelists to succeed today. Key Takeaways: Coming from the IT sector, Mike's experience from CIO to CPO gives him unique insight into the role of procurement and how it needs to evolve to bring the most impact to the business.  Learn about the advanced technologies that Mike warns procurement professionals not to ignore if they don't want to leave money on the table or put their own jobs at risk. When it comes to digital transformation, Mike outlines the specific skill sets that procurement leaders need in order to be successful in their own roles, as well as what it takes to build great teams and retain that talent.

Healing Guide, Intuitive Channel, and Depth Hypnosis Practitioner Rhiannon Morsch joins Eryn to talk about working with personal trauma to heal the collective experience. We talk about her awakening & process stepping into her intuitive gifts, what it means to be an intuitive channel, healing her matrilineal line, how to work with new traumas so they don't get shoved down and rejected, reprogramming your subconscious, the 6 of swords & deprogramming, energetic boundaries, and healing sexual trauma, self-judgment, and shame. Trigger warning: sexual trauma, rape. Blog for this episode: www.living-open.com/rhiannon-morsch  Check out Rhiannon's website & channeled group healing and follow her on Instagram. Follow me on Instagram.  Support on Patreon for as little as $2 a month to access this month's Queen of Cups embodied tarot classes, the Queen of Pentacles breathwork meditation, the Living Open: Scorpio Edition Zine, monthly virtual new moon circles, & our book club: www.patreon.com/erynjohnson. Purchase the Living Open Scorpio Edition Zine featuring candle magick for creativity, a simple spell for abundance, tips for coming out of the broom closet, a note on simplifying, a restorative yoga practice for the astrology of the rest of the year, tarot spreads to connect with the King of Cups and check in on your relationship with Death, entering the Death card, musings on feeling like a fraud (maybe you can relate?), journaling prompts, and more.

Comment avoir des revenus automatiques, en créant un simple blog et obtenir ses premiers clients en 30 jours : margauxklein.com/club Comment passer au niveau supérieur avec son business et son CA : margauxklein.com/coaching

Rhiannon Morsch, a practitioner of Depth Hypnosis and shamanic healing, has experienced a life of sexual trauma, PTSD, and addiction. Rhiannon talks with Natalie in the episode about healing her extreme anxiety, depression, and substance abuse. We also talk about: How spirit guides speak to us and how to ask them for information Identifying with […]

Rhiannon Morsch, a practitioner of Depth Hypnosis and shamanic healing, has experienced a life of sexual trauma, PTSD, and addiction. Rhiannon talks with Natalie in the episode about healing her extreme anxiety, depression, and substance abuse. We also talk about: How spirit guides speak to us and how to ask them for information Identifying with […]

It was the 1970s; Big hair, bell-bottomed pants, Elvis sideburns and puka shell necklaces. The drugs, the freedom, the Me Generation, the lime green leisure suits.  And then there was the music and how it defined a generation. The birth of Philly soul, the Jersey Shore Sound and disco.  The stories behind the memorable albums in The Vinyl Dialogues, The Vinyl Dialogues Volume II: Dropping the Needle and The Vinyl Dialogues Volume III: Stacks of Wax will surely resonate with many — from the artists crafted them to the listeners, like you and me, who still appreciate the music that filled up the soundtracks of our lives.  Throw in a little political intrigue - The Guess Who being asked not to play its biggest hit, "American Woman," at a White House appearance and Brewer and Shipley being called political subversives and making President Nixon's infamous "enemies list" - and The Vinyl Dialogues and The Vinyl Dialogues Volume II: Dropping the Needle offers a first-hand snapshot of a country in transition, hung over from the massive cultural changes of the 1960s and ready to dress outrageously and to shake its collective booty.  All seen through the eyes, recollections and perspectives of the artists who lived it and made all that great music on all those great albums.  Mike Morsch is a 40-year veteran of the newspaper business, having served as a reporter, columnist, and editor at newspapers in Iowa, Illinois, Pennsylvania and New Jersey. Mike has earned several awards for his writings from the Illinois Press Association, Suburban Newspapers of America (now the Local Media Association), the Pennsylvania Newspaper Association, the Philadelphia Press Association and the New Jersey Press Association. He has written four books: "Dancing in My Underwear: The Soundtrack of My Life" in 2012; and three in "The Vinyl Dialogues series, including "The Vinyl Dialogues: Stories behind memorable albums of the 1970s as told by the artists" in 2014; "The Vinyl Dialogues Volume II: Dropping the Needle" in 2015; and "The Vinyl Dialogues Volume III: Stacks of Wax" in 2016.   Find all of Mike's books on Amazon and on Mike on Facebook here.    Please subscribe, rate and review and head over to Patreon to help support our network of rock based podcast.

Prof. Dr. Günter Morsch ist Leiter der Gedenkstätte und des Museums Sachsenhausen und Direktor der Stiftung Brandenburgische Gedenkstätten. Außerdem lehrt der Historiker am Otto-Suhr-Institut für Politikwissenschaft an der FU Berlin.

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Long Live Rock: Mike Morsch on the Rock of the 70's by Vegas Never Sleeps Experience the excitement and energy of Las Vegas each weekend on VEGAS NEVER SLEEPS with Steven Maggi.