Podcasts about amyotrophic lateral sclerosis als

We talk about motor neurone disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS), with Pauline from the MND Association and Joff, who shares what diagnosis and day-to-day life really look like. We explore how symptoms show up, why support and research urgency matter, and how small acts of understanding can make public spaces safer and kinder. What MND is and why symptoms vary so much The long process of ruling out other conditions Prevalence Resilience and adapting to changeThe helpful role of the Sunflower in preventing being misjudgedIf you are concerned about any of the subjects discussed in the podcast, please follow up with your healthcare practitioner for support.For supportMND Association UKIrish Motor Neurone DiseaseThe ALS Association USAALS CanadaHosted by Chantal Boyle, Hidden Disabilities Sunflower. If you enjoyed this podcast, please leave a rating and review. Find out more about the Sunflower by visiting the website hdsunflower.comMusic by © Sandee Facy / Michael Saleta www.sandeefacy.com.au

In this episode, we discuss the complexities of predictive genetic testing in Amyotrophic Lateral Sclerosis (ALS) from Dr. Jade Howard's recent study. Learn how it impacts decision-making and what it means for families.   Article: “Predictive genetic testing in amyotrophic lateral sclerosis (ALS): Experiences of decision-making and engagement with UK genetic counseling services”   In this episode we discuss: - The decision-making process surrounding predictive testing - Navigating family dynamics and personal goals - The uncertainty that comes with genetic risks - The need for tailored communication and ongoing support after testing   Guest Bio: Dr Jade Howard is a postdoctoral researcher at Sheffield Institute for Translational Neuroscience, University of Sheffield, UK. Her research focuses on genetic testing in motor neuron disease (MND/ALS), and the development of interventions to help families navigate decisions around testing and the disclosure of results.   Resources: - This research is being led by PI Dr Alisdair McNeill, with the support of the study team Prof Hilary Bekker and Prof Chris McDermott, and a project steering committee. The team are grateful to The MND Association for funding this work and all the participants who took part. - If you are interested in the decision aids discussed in this podcast, they can be found here: https://mymndgenetest.shef.ac.uk/   Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.

Amyotrophic lateral sclerosis (ALS) is a rare, progressive, and fatal neuromuscular disease for which there is currently no known cure. It typically manifests in mid-to-late adulthood and progresses rapidly with a median survival time of two to five years, though it can sometimes progress faster. It's currently diagnosed through a long process that can often take well over a year. We learn about a new technique developed at the nonprofit Brain Chemistry Labs in Jackson, Wyoming that can diagnose ALS with a simple blood test with 97% accuracy.

Did you know that there is hope for patients diagnosed with ALS? Amyotrophic Lateral Sclerosis (ALS), the debilitating neurodegenerative disease commonly known as “Lou Gehrig's Disease,” is influenced by genetics and environmental factors, including living near bodies of water frequently impacted by harmful algal blooms. Join Food Sleuth Radio host and Registered Dietitian, Melinda Hemmelgarn for her conversation with Coco Newton, RD, MPH, CNS, a registered dietitian and holistic practitioner with expertise in functional medical nutritional therapy for improving the diet quality and quality of life for those diagnosed with ALS. Newton has been involved with Healing ALS: www.healingALS.org. She references the ALS Clinic at Duke University: https://alsclinic.duke.edu/our-research/ and the international conference on ALS and Motor Neurone Disease will be held Dec 5-7 in San Diego, CA: https://symposium.mndassociation.org/programme/. To learn more about algal blooms and neurodegenerative disease, see: https://www.eurekalert.org/news-releases/1087706 Related Websites: https://www.coconewton.com/

Send us a textDr. Fred Grossman, D.O., FAPA is President and Chief Medical Officer of Coya Therapeutics ( https://coyatherapeutics.com/ ), a clinical-stage company focused on developing multi-modality, Regulatory T Cell (Treg) therapies for neurodegenerative diseases. Coya has already developed strong proof of concept data in Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's, and is also active in the autoimmune and metabolic disease domains.Dr. Grossman brings over 20 years of drug development expertise having held senior executive leadership positions in large and small pharmaceutical companies, leading the development and FDA approval of numerous multi-billion dollar blockbuster drugs addressing significant unmet medical needs particularly across CNS disorders. He has close relationships with thought leaders worldwide and has negotiated directly with the FDA and Global Health Authorities for approval of many drugs across therapeutic areas. Dr. Grossman held executive positions at Eli Lilly, Johnson & Johnson, Bristol Myers Squibb, and Sunovion. He served as President and Chief Medical Officer at Glenmark Pharmaceuticals, a $1.5 Billion per annum global pharmaceutical company based in India, overseeing development of an entire pipeline including generics, complex generics including 505(b)(2) candidates, and next-generation biologics (including bi-specific antibodies). Dr. Grossman also previously served as Chief Medical Officer at Mesoblast, Inc., developing allogeneic cellular therapies for inflammatory diseases. Dr. Grossman is Board-Certified in Psychiatry and a Fellow of the American Psychiatric Association and was a Fellow at the National Institutes of Health (NIH). He has held several academic appointments and authored numerous scientific publications.#RegulatoryTCells #Tregs #AutoimmuneDisorders #ShimonSakaguchi #ImmuneSystem #FredGrossman #CoyaTherapeutics #NeurodegenerativeDiseases #AmyotrophicLateralSclerosis #ALS #Alzheimers #CNSDisorders #StanleyAppel #Immunomodulation #ProInflammatoryCytokines #SelfTolerance #Microglia #Macrophages #CTLA4Ig #LowDoseIl2 #FusionProtein #ImmuneCheckpointModulator #FrontotemporalDementia #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

In this episode of the Brain and Life podcast, host Dr. Daniel Correa is joined by Dr. Richard Bedlack, Stewart, Hughes, and Wendt Distinguished Professor of ALS at Duke and director of the Duke ALS Clinic. They discuss the complexities of ALS, focusing on the journey of Brooke Eby, an advocate and former podcast guest who shares her experiences on social media. Dr. Bedlack answers your questions and covers the progression of ALS, the importance of measuring quality of life beyond physical symptoms, the challenges in diagnosing ALS, the emotional impact of receiving a diagnosis, and how hope can go a long way.   Additional Resources Turbocharged Living Tool Stitching Strength: A Film What is Amyotrophic Lateral Sclerosis (ALS)?   Other Brain & Life Podcast Episodes on These Topics Making the Years Count with Brooke Eby, Influencer Living with ALS Finding Strength in ALS Advocacy with Podcaster Lorri Carey Hop on a Cure for ALS with John Driskell Hopkins We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? ·       Record a voicemail at 612-928-6206 ·       Email us at BLpodcast@brainandlife.org   Social Media:   Guests: Dr. Rick Bedlack @stitchingstrength; Brooke Eby @limpbroozkit Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD

Discover Lafayette welcomes Dale Clark, Ursula Quoyeser, and Harriet Hoag to discuss the upcoming 4th annual Fin Feather Fur Food Festival ("F5"). This event raises funds for the Team Gleason Foundation, which supports individuals living with Amyotrophic Lateral Sclerosis (“ALS”). Team Gleason, through its diverse and broad-reaching programming, brings assistive technology, equipment, and robust support services into the hands of ALS patients – to help individuals with ALS not just survive but thrive after a devastating diagnosis. Each of our guests has either been personally affected by ALS or has supported a loved one with the disease. Event Details: Date: April 24, 2025 Time: 4:00 PM - 8:00 PM Location: Blackham Coliseum, Lafayette, LA Tickets: $45 Website: https://teamgleason.org/f5/ Attendees can enjoy great food, beer, and wine while supporting a worthy cause. F5 is a cooking competition where teams compete in four categories: Fin, Feather, Fur, and Dessert. Awards will be given to the best dishes, a "People's Choice" winner, and a "Team Showmanship" winner chosen by a panel of judges. Additionally, a silent auction will offer a selection of valuable items. Teams also compete to raise the most funds for Team Gleason, with prizes awarded to top fundraisers. About Team Gleason Foundation: In January 2011, New Orleans Saints star Steve Gleason was diagnosed with ALS. Faced with this devastating diagnosis, Steve embraced a new mission: to show that people with ALS can not only live but thrive and to inspire others facing similar challenges. “People were simply expected to fade away quietly and die, that was not acceptable to me. That is not OK.” Steve and his wife, Michel Varisco, founded Team Gleason, a nonprofit dedicated to helping individuals with ALS lead purposeful and fulfilling lives.  Team Gleason has provided over $55 million in resources to individuals with ALS. Their work includes supplying mobility equipment, power seat elevators, speech-generating devices, and essential home modifications. Personal Impact of Team Gleason: Ursula Quoyeser's Experience Ursula has received significant support from Team Gleason. These resources have been life-changing, enabling her to maintain independence. Ursula reflects on how Team Gleason anticipates needs before they arise, ensuring that people living with ALS receive assistance promptly. One of the most important things that Team Gleason provides is pathways of communication to connect ALS families with each other so that resources that are no longer needed are generously shared. Many of you know Ursula as a superstar Volleyball coach! She is still a superstar and it is an honor to share her story so that the Team Gleason message may be distributed to a wide audience! Harriet Hoag's Journey Harriet's late husband, Monty, was diagnosed with ALS during the height of COVID-19, making the journey even more isolating. Doctors struggled to diagnose him, but Harriet's own research led them to Baylor Hospital, where they received confirmation. She credits Team Gleason for providing invaluable resources such as a speech-generating device that allowed Monty to communicate with their granddaughter even in his final days. Dale Clark's Commitment After being diagnosed with ALS, Dale was inspired to help others in the ALS community. Witnessing the challenges faced by fellow patients at his clinic in Houston, he saw the opportunity to make a difference. His dedication, alongside generous contributions from local companies like Badger Oil and Gas and Service Chevrolet, has helped F5 grow into a major fundraising success. For a more in-depth interview we did in 2024 with Dale and Ursula, listen here. Dale Clark says, "100% of the money goes to Team Gleason. In fact, we tell people to mail their check to Team Gleason so we don't have to handle any money. The Importance of Fundraising: Over the past three years,

Joe was born and raised in Philadelphia, Pennsylvania and since childhood he has loved the Philadelphia Phillies. According to him, “I live and die with the Phillies, no matter where they are in the standings. They have been playing great of late and that makes me happy!” Now a Nashvillian for almost five decades, Joe is also a Tennessee Titans football fan. He has had season tickets since they arrived in Nashville in 1998. Joe is an avid writer and songwriter and became a published children's book author in 1997 with The Molly Books, a four-book series published by Ideal's Children's Books. In 2003, New Leaf Press published G. I. Joe and Lillie: Remembering a Life of Love and Loyalty, an inspirational biography Joe penned about his parents. His song by the same name was included on the Oaks' Colors album, released the same year. A music video of the song reemerged in the summer of 2009 and became a YouTube phenomenon with almost six million views. Joe also wrote the title song for the Oaks' The Journey album, as well as the text for The Oak Ridge Boys' coffee table book, An American Journey, published in 2004. In 2014, New Leaf published Joe's Christmas short story, An Inconvenient Christmas, which was inspired by an Oak Ridge Boys' song from an album by the same name. In September 2010, Journey Press, a division of Sheaf House, released From My Perspective, a collection of Joe's commentaries, stories, and other writings. His book Christmas Miracles, a collection of Christmas short stories and commentaries, originally published in 2008, was updated in 2012. His most recent book, On the Road with The Oak Ridge Boys, was published by Harvest House Publishers in May 2015. For relaxation, Joe retreats to his farm on the Tennessee-Kentucky state line, where he can often be found on his John Deere tractor mowing part of his 350-acres—or sitting on his front porch and playing banjo, an instrument he has played for more than a decade. He plays a step-out lead on the Oaks' Rock of Ages CD. Joe has been singing since he was about four years old and in his mid-teens fell in love with Southern Gospel music harmony. A born-again Christian, he is always quick to give God the credit for everything he has accomplished. He joined the Oaks in 1973, just prior to the group's emergence on the Country music scene. As with the other group members, much of Joe's time has been spent on the road performing, but he found his own way to get the maximum possible enjoyment out of touring. “My life has been simple,” says the Oak who was the principal spokesman on stage for five decades. “I go out there and try to sing the best I can and give them physically and mentally everything I've got. When it's done, I go back to my room or the bus, eat some pizza or sushi, call my Mary, get on my Apple laptop, do a little writing, and say to myself, ‘Hey, I've done what I'm supposed to be doing and I feel great about it.'” Joe and his wife, Mary, have two daughters, Jennifer, and Sabrina; two grandchildren, Breanne and Luke, who recently served in the U.S. Navy; and one great grandson, Noah Chance. They also have four cats, Mitty, Crockett, Barney, and Maggie Mae. In early 2024, Joe announced his retirement from touring due to the onset of a neuromuscular disorder. He passed on to Glory on July 9, 2024, due to complications from Amyotrophic Lateral Sclerosis (ALS). He leaves behind his precious wife, Mary Ann, daughters Jennifer and Sabrina, granddaughter Breanne, grandson Luke, two great grandsons, Chance and Grey, and a sister, Nancy. He is preceded in death by his parents Joseph S. Bonsall Sr. and Lillie Bonsall. A memoir written by Joe in early 2024, entitled I See Myself, will be released in November.

Joe was born and raised in Philadelphia, Pennsylvania and since childhood he has loved the Philadelphia Phillies. According to him, “I live and die with the Phillies, no matter where they are in the standings. They have been playing great of late and that makes me happy!” Now a Nashvillian for almost five decades, Joe is also a Tennessee Titans football fan. He has had season tickets since they arrived in Nashville in 1998. Joe is an avid writer and songwriter and became a published children's book author in 1997 with The Molly Books, a four-book series published by Ideal's Children's Books. In 2003, New Leaf Press published G. I. Joe and Lillie: Remembering a Life of Love and Loyalty, an inspirational biography Joe penned about his parents. His song by the same name was included on the Oaks' Colors album, released the same year. A music video of the song reemerged in the summer of 2009 and became a YouTube phenomenon with almost six million views. Joe also wrote the title song for the Oaks' The Journey album, as well as the text for The Oak Ridge Boys' coffee table book, An American Journey, published in 2004. In 2014, New Leaf published Joe's Christmas short story, An Inconvenient Christmas, which was inspired by an Oak Ridge Boys' song from an album by the same name. In September 2010, Journey Press, a division of Sheaf House, released From My Perspective, a collection of Joe's commentaries, stories, and other writings. His book Christmas Miracles, a collection of Christmas short stories and commentaries, originally published in 2008, was updated in 2012. His most recent book, On the Road with The Oak Ridge Boys, was published by Harvest House Publishers in May 2015. For relaxation, Joe retreats to his farm on the Tennessee-Kentucky state line, where he can often be found on his John Deere tractor mowing part of his 350-acres—or sitting on his front porch and playing banjo, an instrument he has played for more than a decade. He plays a step-out lead on the Oaks' Rock of Ages CD. Joe has been singing since he was about four years old and in his mid-teens fell in love with Southern Gospel music harmony. A born-again Christian, he is always quick to give God the credit for everything he has accomplished. He joined the Oaks in 1973, just prior to the group's emergence on the Country music scene. As with the other group members, much of Joe's time has been spent on the road performing, but he found his own way to get the maximum possible enjoyment out of touring. “My life has been simple,” says the Oak who was the principal spokesman on stage for five decades. “I go out there and try to sing the best I can and give them physically and mentally everything I've got. When it's done, I go back to my room or the bus, eat some pizza or sushi, call my Mary, get on my Apple laptop, do a little writing, and say to myself, ‘Hey, I've done what I'm supposed to be doing and I feel great about it.'” Joe and his wife, Mary, have two daughters, Jennifer, and Sabrina; two grandchildren, Breanne and Luke, who recently served in the U.S. Navy; and one great grandson, Noah Chance. They also have four cats, Mitty, Crockett, Barney, and Maggie Mae. In early 2024, Joe announced his retirement from touring due to the onset of a neuromuscular disorder. He passed on to Glory on July 9, 2024, due to complications from Amyotrophic Lateral Sclerosis (ALS). He leaves behind his precious wife, Mary Ann, daughters Jennifer and Sabrina, granddaughter Breanne, grandson Luke, two great grandsons, Chance and Grey, and a sister, Nancy. He is preceded in death by his parents Joseph S. Bonsall Sr. and Lillie Bonsall. A memoir written by Joe in early 2024, entitled I See Myself, will be released in November.

Osteosarcoma Webinar Series: Osteosarcoma Webinar Series: One of our MIB Agents OutSmarting Osteosarcoma 2024 grant recipients, Dr. Shahana Mahajan, a Professor and Principal Investigator from Hunter College of the City University of New York will provide an overview of her funded work on repurposing drugs for metastatic osteosarcoma. Dr. Mahajan will share the recent findings from her lab on testing the efficacy of Riluzole in osteosarcoma cell lines and patient-derived cell lines. Riluzole is a glutamate-release inhibitor and has been used for Amyotrophic Lateral Sclerosis (ALS) for decades and is being tested for other neurodegenerative disorders. Riluzole has shown promising results in glutamate receptor-expressing melanoma and other cancer types. The Mahajan Lab efforts are invested in establishing Riluzole as a possible treatment option for osteosarcoma for which targeted therapy has not been successful due to lack of oncogenic driver mutations. In their lab, Riluzole has shown efficacy in inhibiting proliferation, migration, and invasive ability of osteosarcoma cells in 11 cell lines and 4 patient-derived lines. Dr. Mahajan earned a Ph.D. from the Indian Institute of Science, a premier Institute in India in the field of Molecular Biology. She did postdoctoral studies at Weill Cornell Medical College in the Department of Pharmacology and at NYU Langone Medical Center in the Department of Biochemistry. She continued her research at NYU Langone Medical Center as a Research Assistant Professor until she joined Hunter College as an Assistant Professor in 2007. At Hunter, she continued her research neuroscience to investigate glutamate-induced excitotoxicity in rat hippocampal neurons. After her lab was lost to Hurricane Sandy, she reinitiated her research in osteosarcoma. In 2015, her lab moved to Belfer Research Building which is a part of Weill Cornell Medical College. She was appointed as an adjunct faculty at Weill Cornell Medical College. After a short presentation on this research, she will take questions from attendees. Share your questions in advance with us at Christina@MIBAgents.org.

Send us a textWhen Benson St. Louis, a strong and active father and husband, began experiencing unusual physical symptoms in 2022, he and his wife, Karol, embarked on a year-long journey of testing and doctor visits. After ruling out various possibilities, they received a heartbreaking diagnosis: Benson had Amyotrophic Lateral Sclerosis (ALS). In this episode, Benson and Karol discuss how they have adjusted to life after the diagnosis and share how their faith has helped them face one of life's most difficult challenges with grace, love, and humor.Mentioned in the Episode:Watch Steve Gleason's speech from the Espy's here.Find Steve Gleason's book here. Thanks for listening to the Embodied Holiness Podcast. We invite you to join the community on Facebook and Instagram @embodiedholiness. You can find all our episodes and more at www.embodiedholiness.com. Embodied Holiness is a ministry of Parkway Heights United Methodist Church in Hattiesburg, MS. If you're in the Hattiesburg area and are looking for a church home, we'd love to meet you and welcome you to the family. You can find out more about Parkway Heights at our website.

In this episode of the Brain & Life podcast, award-winning actor, singer, and advocate Aaron Lazar joins co-host Dr. Daniel Correa to discuss his journey with amyotrophic lateral sclerosis (ALS) and how it has affected his daily outlook on life. Aaron shares about his symptoms, diagnostic journey, and how he is continuing to find hope. Dr. Correa is then joined by Dr. Richard Bedlack, Stewart, Hughes, and Wendt Distinguished Professor of ALS at Duke and director of the Duke ALS Clinic. Dr. Bedlack explains just how he is helping his patients find hope in their ALS journeys while also making realistic plans for the future.   Additional Resources Aaron Lazar's “The Impossible Dream” What is Amyotrophic Lateral Sclerosis (ALS)? A Marathoner on a Quest to End ALS Steve Gleason, ALS Advocate and NFL Veteran, Receives Courage Award   Other Brain & Life Episodes on this Topic Making the Years Count with Brooke Eby, Influencer Living with ALS Finding Strength in ALS Advocacy with Podcaster Lorri Carey Hop on a Cure for ALS with John Driskell Hopkins   We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? ·       Record a voicemail at 612-928-6206 ·       Email us at BLpodcast@brainandlife.org   Social Media:   Guests: Aaron Lazar @aaronscottlazar; Dr. Richard Bedlack @stitchingstrength Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD

Send us a textHad the pleasure of speaking with "Dynamite Doll" Bronwyne Billington! Billington is the daughter of the late "Dynamite Kid" Tom Billington, who passed away in 2018. On episode 130, we discussed growing up in a wrestling family, how she reconnected with her father after a long stretch of time, entering the wrestling business, raising awareness of Amyotrophic Lateral Sclerosis (ALS), and more. You can find out more about Billington here:https://www.instagram.com/bronwynejewel/https://x.com/Dynamitedoll84https://www.patreon.com/DynamiteDoll?utm_campaign=creatorshare_creatorCheck out the Dynamite Kid IG page here:https://www.instagram.com/officialdynamitekid/Are you a pro wrestler and have done community service and/or charity work? E-mail the podcast at wrestlingwithheart@yahoo.com and tell us if you would be interested in being interviewed.Follow us on:Facebook: Wrestling with Heart with Stanley KarrX: @wwhwskInstagram: @wrestlingwithheartThreads: @wrestlingwithheartHear Wrestling with Heart on Apple Podcasts: https://podcasts.apple.com/us/podcast...Hear Wrestling with Heart on Spotify: https://open.spotify.com/show/46cviL5...Hear Wrestling with Heart on iHeartRadio: https://www.iheart.com/podcast/269-wr...Hear Wrestling with Heart on Google Podcasts: https://podcasts.google.com/search/Wr...Donate to my Patreon and subscribe to my content here: https://www.patreon.com/user?u=84502525Support the show

Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS) are they one and the same? Is ALS and MS sometimes caused by caused by the Herpes Zoster Virus? Epstein Barr Virus (EBV) and Cytomeglavirus (CMV), which are forms of Herpes virus are they related. Yes these all can be cured! In this episode we will discuss all the possibilities that these life taking and life changing diseases may all be related and treatable in a safe, though unconventional way.

Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS) are they one and the same? Is ALS and MS sometimes caused by caused by the Herpes Zoster Virus? Epstein Barr Virus (EBV) and Cytomeglavirus (CMV), which are forms of Herpes virus are they related. Yes these all can be cured! In this episode we will discuss all the possibilities that these life taking and life changing diseases may all be related and treatable in a safe, though unconventional way.

Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease that destroys nerve cells, mostly in the Central Nervous Systems (Brain and Spinal Cord). It affects control of the voluntary muscle movements needed to move, speak, eat and breathe. Listen to this very interesting podcast where Dr. Zahra Figueredo explains how the Stem Cell Treatment can help to stop the progresiveness of this condition. #stemcells #StemCellTreatment #StemCellTherapy #ALS #AmyotrophicLateralSclerosis __________________________________________________ Could Dr. Zahra's Natural and Unique Stem Cell Therapy Transform Your Life? "My heart and soul sing when we see what an incredible impact we can make on the lives of our patients and their families with our natural and comprehensive stem cell therapies." Dr. Zahra Figueredo. Canadian Dr. Zahra Figueredo has successfully treated 1,000+ patients from the USA and Canada suffering with hundreds of different health problems in her Stem Cell Healing Institute in Guatemala - 'the land of eternal Spring' - with her safe, comprehensive, non-surgical and innovative stem cell therapies. It's important to note that Dr. Zahra's powerful stem cell combination therapy is NOT available anywhere in the USA or Canada. What To Do Now? New Patient? - Learn how Dr. Zahra's combined stem cell healing could transform your life. Please send us an email. info@stemcellhealinginstitute.com For more information on stem cell treatment please visit our website

Guest: Emily Kornman, MCD, CCC-SLP - Emily brings Team Gleason to you in this one-hour conversational audio course podcast. Team Gleason is a 5013(c)(3) organization founded in 2011 by Steve and Michel Gleason - Team Gleason has provided over $40 million in adventure, technology, equipment, and care services to people living with Amyotrophic Lateral Sclerosis (ALS) and countless others through advocacy and support. Emily highlights how Team Gleason supports people with ALS and their families with an interdisciplinary approach. She describes how SLPs can support speech, swallowing, voice preservation, and AAC options to empower people with ALS to live purposeful lives.

This week on the Life Science Success Podcast, my guest is Dr. Tiago Reis Marques Dr. Marques is a psychiatrist and currently the Chief Executive Officer of Pas i thea Therapeutics. Pasithea is developing new molecular entities for the treatment of CNS disorders, including Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis, Neurofibromatosis type 1 and Noonan syndrome.   On this episode of Life Science Success, Don Davis interviews Dr. Tiago Reis Marques, the CEO of PACEA Therapeutics. They discuss Dr. Marques's journey in psychiatry, the company's focus on CNS disorders, their pipeline of drugs targeting neurological conditions like schizophrenia and ALS, and the impact of their research on rare disorders like neurofibromatosis type one. The conversation also touches on leadership advice, inspiration, concerns about global issues, and what excites them. Dr. Tiago Reis Marques, a psychiatrist, is the CEO of Pasithea Therapeutics, a company focused on central nervous system (CNS) disorders. His background in medical research and his transition from academia to biotech were driven by a desire to apply his knowledge to develop treatments that benefit patients. Pasithea Therapeutics, co-founded with Professor Steinman from Stanford, aims to create innovative therapies for unmet needs in CNS disorders. The company's approach balances new drugs targeting novel mechanisms of action with known drugs repurposed for new applications. One of the company's focuses is on neurofibromatosis type one, a disorder affecting around 100,000 patients in the US, highlighting the company's commitment to tackling rare and challenging diseases with significant unmet needs. Marques emphasizes the importance of precision psychiatry and targeting specific subtypes of disorders, drawing parallels to how cancer treatments have evolved to focus on specific biomarkers and subtypes, reflecting a broader trend towards personalized medicine. His experiences and work in brain imaging, specifically with positron emission tomography (PET) and psychopharmacology, underscore his multidisciplinary approach to understanding and treating CNS disorders, leveraging his academic background to inform his leadership and strategic direction at Pasithea Therapeutics.

Stephanie Morales-Beaulieu will never forget the day her dad called to tell her he had been diagnosed with Amyotrophic Lateral Sclerosis (ALS). The doctor had given him three to five years to live. This propelled Stephanie into a season she did not think she would survive. After experiencing what a little bit of trust in God's faithfulness can accomplish, Morales-Beaulieu was compelled to share this message, and her father's life, legacy and love for Jesus in her first book, Anything But Ordinary.  Today on Connections, Stephanie shares her family's story and how it has helped grow her faith.See omnystudio.com/listener for privacy information.

Welcome to this episode of The Genetics Podcast as we host Dr. Michael Benatar, a preeminent figure in the fight against Amyotrophic Lateral Sclerosis (ALS). Michael is a Professor of Neurology, the Chief of the Neuromuscular Division, and the Executive Director of the ALS Center at the University of Miami's Miller School of Medicine. Tune in as he and Patrick discuss research and treatment for presymptomatic gene carriers and other people at risk for ALS, as well as the future of ALS research.

Parkinson's is the second most common neurological disease after Alzheimer's and affects about one percent of people over sixty. The symptoms develop slowly. These include rigidity, a characteristic resting tremor, and movement dysfunction with walking problems. As it progresses, problems with sleep, thinking, and eventually dementia may occur. Survival after diagnosis is seven to fifteen years. Like many neurological problems, PD is a syndrome with recognized clinical characteristics rather than a clearly defined disease with definitive lab tests and treatments. Genetics have been weakly implicated, but cannot be the primary cause because the incidence is skyrocketing. Parkinson's (PD), Autism, Alzheimer's (AD), Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) are likely caused by toxins. Ken Stoller lays out some of the evidence implicating glyphosate in Incurable Me: Why the Best Medical Research Does Not Make It into Clinical Practice (2015). US government databases were searched for… crop data, glyphosate application data and disease epidemiological data. Correlation analyses were then performed on a total of 22 diseases… Correlation coefficients are highly significant (< 10–5) between glyphosate applications and hypertension (R = 0.923), stroke (R = 0.925), diabetes prevalence (R = 0.971), diabetes incidence (R = 0.935), obesity (R = 0.962), lipoprotein metabolism disorder (R = 0.973), Alzheimer's (R = 0.917), senile dementia (R = 0.994), Parkinson's (R = 0.875), multiple sclerosis (R = 0.828), autism (R = 0.989), inflammatory bowel disease (R = 0.938), intestinal infections (R = 0.974), end stage renal disease (R = 0.975), acute kidney failure (R = 0.978), cancers of the thyroid (R = 0.988), liver (R = 0.960), bladder (R = 0.981), pancreas (R = 0.918), kidney (R = 0.973) and myeloid leukaemia (R = 0.878). He also says that many other toxins increase the chances of developing PD. Paraquat exposure, for example, increases the risk 2.5-fold. Ken goes on:The latest research shows that AD, PD, and ALS share a common, or at least overlapping, pathologic mechanism(s).98 This implies that AD, PD, and ALS are essentially the same disease with a slight variation on a theme. The theme is pesticide poisoning, and there is a synergistic99 effect of heavy metals (think aluminum and mercury)…Assuming one does not have Lyme or Parkinsonism from a toxic exposure, such as carbon monoxide, it is worth a trial of 4-PAS or 5-ASA, which will selectively chelate manganese (Mn) from the human body. Mn is an essential trace element but can be absorbed or ingested in toxic forms and in excess. Exposure can be from gasoline to well water. If the 4-PAS or 5-ASA changes symptoms, this is about Mn toxicity issues.119 Glutathione is not a specific detoxification agent for just Mn, but a large dose will help remove some of it. Mesalazine, also known as mesalamine, is 5-aminosalicylic acid (5-ASA), and like 4-PAS is considered by conventional medicine to be anti-inflammatory because it helps treat inflammatory bowel disease. It is the active part of the antibiotic sulfasalazine, which is used to treat Crohn's disease.for more, see https://robertyoho.substack.com/p/244-wholistic-treatments-for-parkinsons#detailsSupport the show

Zoe Lalji is a junior at UT Austin studying neuroscience with a minor in entrepreneurship on a pre-med track, and she is working to make virtual reality accessible to ALS patients. In this episode, she discusses what it was like when her dad was diagnosed with ALS and how that changed the trajectory of her career, her work with advancing virtual reality technology to better support patients' lives, and how hardship has developed an essential self-awareness.   Guest links: https://www.linkedin.com/in/zoe-lalji/ Charity supported: ALS Heroes Interested in being a guest on the show or have feedback to share? Email us at podcast@velentium.com.  PRODUCTION CREDITS Host: Lindsey Dinneen Editor: Tim Oliphant Producer: Velentium   SHOW TRANSCRIPT Episode 010 - Zoe Lalji Lindsey Dinneen: Hi, I'm Lindsey with Velentium and I'm talking with MedTech industry leaders on how they change lives for a better world. Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello and welcome to The Leading Difference. I'm your host Lindsey, and I am so excited to introduce you to my guest today, Zoe Lalji. Zoe is a junior at UT Austin studying neuroscience with a minor in entrepreneurship on a pre-med track. Her passion for neuroscience began when her father was diagnosed with a Amyotrophic Lateral Sclerosis (ALS) in 2017. And since then, she has been constantly searching for ways to improve his quality of life and expand his avenues of connection with the world around him. As part of this work, she is working to make virtual reality accessible to ALS patients and other highly disabled populations as a way to provide them with autonomy in the form of novel experiences and immersive activities that they're unable to engage in physically. Zoe, oh my gosh, thank you so very much for joining us. I am just so very delighted that you're here and I just can't wait to hear more about your story and your background. But first, thank you just so much for being here. Zoe Lalji: Aw. Thank you, Lindsey. Thank you so much for inviting me. It's awesome to be a part of this great podcast you have. Lindsey Dinneen: Awesome. Well, I was just wondering if you wouldn't mind starting by just telling us a little bit about yourself and your background and what led you to what you're doing now. Zoe Lalji: Sure. So, right now I'm a junior at UT Austin and I'm studying neuroscience on a pre-med track and minoring in entrepreneurship. And as far as what kind of got me to where I'm at and-- I've been passionate about medicine for as long as I can remember. Both of my parents are in medicine. My dad was a dentist and my mom studied as a gynecologist and transferred into functional medicine. And they both had their own practices, so I've had that business background as well. But that all shifted, I would say, when my dad was diagnosed with ALS in 2017. And from there it was a pause button if you could say on on my entire scheme of my life, my plans. You know, I think with pre-meds there's a track that is a starting point and you have a series of events that are lined out for you until you reach medical school and get that MD. And that kind of stopped me in my tracks and made me reassess what was truly important because I had to spend a lot of time caring for my dad, caring for my family, and it definitely shifts your priorities and makes you reassess your life. And although, everything was still of in line with my values growing up, which was, I've always wanted to help people and that's what drew me to medicine. That's what I had really admired about my parents is the impact they had made on others' lives that were struggling, that had health conditions and needed guidance in that area of their lives. And I think watching my dad undergo one of those health conditions and just doing everything in my power to make it better for him in any way that I can. It just truly strengthened that core value for me. And I think when you're in pre-med, there's kind of a tendency to get tunnel vision. And, kind of that check mark mentality where you go, "Do I have the grades? Do I have the volunteer hours, the extracurriculars," all that stuff. And I think, you lose sight of the why of medicine, until even after residency when you're actually in the field where you actually meet the patients and you actually you know, talk to the people that are struggling and realize how important it is. And until then, it's more about, memorizing facts and figuring out how the body works without really putting it into the context of the bigger picture. So I think studying medicine alongside actually understanding what it's like to be on the other side, on the patient perspective, was a real driver for me. I guess the turning point for me for where I really realized that making an impact for medical problems is where my heart really lies. Lindsey Dinneen: Yeah, that is such a powerful story, so thank you for sharing that. I was wondering if you would be willing to share a little bit more about ALS and how that affects people's lives. I know it's a very difficult disease, but just from your perspective, especially having experienced it and trying to help someone who is dealing with it-- I would just love to hear a little bit more about it. Zoe Lalji: Yeah, absolutely. So ALS is a neurodegenerative disease. It impacts the motor neurons in the body, which effectively causes people to lose their ability to walk, talk, move any part of their body and eventually breathe on their own. And it's a interesting disease in that there's not much known about the pathophysiology of it, in that like they don't know what causes it. They don't know how to even approach treatment. Only 10% of ALS cases have been found to be connected to a gene. And even then they haven't really found a way to reverse any of that. So it's a completely uncured disease, the treatment is very limited, in that there's maybe a few months of life expectancy increased by the treatment, but in contrast you get a lot of side effects from it, which effectively makes you pretty much zombified. You know, it's a lot of fatigue, a lot of nausea, and a lot of patients just opt not to do it because the quality of life is really reduced from just being on those treatments. And so it's just a hopeless disease. And when you're given that diagnosis and told that it's always fatal and there's nothing that really you can do, you just feel completely helpless. And then as you lose your agency over your body, your ability to do things on your own, that helplessness sort of grows and consumes you. It's a very difficult disease to be diagnosed with on the patient and the family. Lindsey Dinneen: Of course. Yeah. Well, and I know part of your work, something that you are doing right now is working to make virtual reality accessible to ALS patients. And I love this idea, and I would love if you would be willing to share more about this and what brought that idea about and where is it taking you. Zoe Lalji: Yeah, of course. I love talking about it. This idea came from just my desire and my constant searching for things to do with my dad or things to bring him happiness in his life, or greater quality of life. And it came about from actually an internship I had during my gap year, which I took before college. And I was at a startup accelerator and there was a XR lab in the accelerator where they had virtual reality headsets, and I had talked to the head of the lab and he let me use one of his headsets and I ended up using Google Earth on the headsets. And I don't know if you've ever used virtual reality, but for whoever has used it, it's very life like, like you actually feel like you're there. You feel like you're walking the streets of Rome or you're in, you're in Paris, or so many different places that you can just click a button and just be fully immersed there. And that's just Google Earth. There's so many other immersive scenarios that you can dive into in virtual reality. And with the immersion of the Metaverse and so many different concepts of the growing interest in virtual reality as a way to have a life outside of the physical life. And just from seeing that Google Earth scenario, immediately I thought, "Wow, this would be incredible for my dad." Because for patients that have all of these life support machines, when they lose their breathing, you have to get a surgery and you have to be basically connected to a machine that controls your breathing. And obviously with that, you can't travel, you can't get on a plane. And for many of these patients, like my dad, you have all these hopes of where you would like to travel one day, things you would like to do one day, and life just happens and you don't end up doing it. But you always think there's time. You always think, " Maybe when I retire, I'll go and travel the world." The common notion that people say. When something like this happens and puts your life in pause where you realize you're never gonna be able to travel again, or you're never gonna be able to skydive or bungee jump or do those bucket list things that you said that you would one day do. And like, even further than that, it's more the things that you used to do every day that sort of defined you, that sort of made you feel like-- for example, my dad would, for as long as I can remember, probably my earliest memory of him is him waking up every morning and going for a run. And he never missed a day. And it was so important to him, like being who he is and his day working out the way he wanted it to, that he had that run, he had to start his day off feeling like himself. And I feel like we all have those hobbies and habits that really all together define who we are. And when you get a disease, not only is it like you're losing all of those things all at once, you start to define yourself as your disease then, because there's nothing else really left. I think for me, virtual reality meant giving those back this semblance of who they once were that they've lost. I think we're all the sum of what we do every day and our dreams and hopes for the future. And when those are taken away, it's who are we really? And that's not even considering the communication that patients lose. So you can't even really express yourself either. So with that, it's like there's this huge disconnect with their identity and I, I just see VR as a way for these patients to enter the world where they don't have to be defined as their disability, where they can do everything that anyone else can in virtual reality. And the problem lies with the modes of interaction with the devices where VR right now has remote controls that you need to use to interact with the environment, and you have to walk around to see the full environment, which for all quadriplegics, there's no really way to do that. So I'm trying to make that aspect accessible for that population so that they can have access to those virtual life-like immersive experiences that can tie them to the things that they used to love or would love to do one day. Lindsey Dinneen: Yeah. So essentially taking some of the existing tech, but putting it into a new method of delivery, I suppose? So that folks who can't, like you said, walk or that can't necessarily interact through a series of controllers or something like that, would be able to still experience those wonderful, immersive things. Is that... Zoe Lalji: Yeah. Yeah, exactly. Lindsey Dinneen: Ok. Wow. Yeah. Oh my goodness. Okay. This is so exciting, just to hear all about this. I know that you are still pursuing medicine and then now you're also pursuing this sort of tech side of things. I understand the background of you coming into it and why, but how have you found these interactions? Have they played out easily? Has it been an odd transition, or how has that all worked out? Zoe Lalji: Yeah, as you can imagine, it's like I have two sort of big things that I love and I'm passionate about and they both take a lot of time and effort and energy. And to say the least, it has been difficult to prioritize one or the other and find the time in the day for both. What I love about medicine is that the hope that we can bring to the patient. I love the innovation of it. I love coming up with solutions that aren't out there, that for the patients like my dad that don't see hope in existing medicine. I wanna be the hope for those patients. And that's, that's how I feel right now. I, I know I will always love every aspect of medicine, but that's what really drives me is that notion of helping those people that are feeling the medicine has failed them, and providing them with unconventional solutions that maybe they didn't think to look for or didn't think that there was one, you know? I think that until there's a cure for some of these diseases, technology can bridge that gap of function and bring back what people have lost. And I've seen it, I've worked with Paradromics as a BCI company in Austin and that was my first exposure since developing my startup into the, the medical technology world. And they're just such a amazing team and they have such a noble cause that they're fighting for and they just wanna help people like my dad. And to be surrounded by people that want to do that and the technology and seeing how impactful it has the potential to be. It really inspired me, especially coming from such a hopeless diagnosis that we had, it really gave my family hope. It gave me hope, and that's the feeling I wanna give to other people. And so my plan right now is to finish out my pre-med prerequisites in college and take a gap year or two to really work on my startup, really work on things like put myself in different environments in the medical technology world, get more experience and really understand my passion and what I can offer to the field. And from there I'll really decide if an MD is the right path for me or if I want to go a different route to get a different degree, you know, and still work within medicine, but not maybe bedside and not maybe in a hospital and not maybe with direct patient care. So yeah, I think that's the route I'm thinking right now? Yeah that's the plan. Lindsey Dinneen: Yeah. That's a great plan. And I love, I love your willingness and your openness to explore and continue to evolve, perhaps, over time in terms of, when you go into a new path and you've had this set of expectations for yourself for a while, that this is where you were going to head. And then things change and I just think it's quite remarkable when someone like you who is obviously very talented, smart, multi-passionate, is able to pivot and say, " I love this aspect, but I also love this aspect and maybe I can do both in a really creative way." I think that's fantastic. Zoe Lalji: Yeah, I mean, it was such a difficult thing for me since I had wanted to do medicine my whole life. It was something that was so ingrained in who I thought I was. Everyone asks you when you meet them, like "What do you wanna do with your life? What are you majoring in? What's your path?" And always it's pre-med, ever since I was a kid, I'd say pre-med, and it's strange to change that. And I think what really helped me get there is my life has been so turbulent and I've had to really get used to things not being how I planned, you know? And like that with my dad's diagnosis, throwing us into a spiral. And then after that actually, the gap year itself was another event that I had not planned for. I had decided to take one because my dad really needed me, and I found in my value scope that really came first before anything else. And then it became a serendipitous decision because in December, after I had taken my gap year, my mom was diagnosed with breast cancer. And luckily she's cancer free now, but we had to go through chemo, radiation, surgery and I could not have dealt with that at college. I had to be home, I had to be with her. And somebody had to take care of my dad. Somebody had to help her keep everything together and keep herself together. And I think, that was probably one of my biggest teachers is that, things are gonna happen. You can't avoid change, and I think that was really difficult to realize that maybe my plan wasn't the right plan for me, and maybe I need to take a second and let myself sit in the ambiguous unknown, which is really uncomfortable, but sometimes it's necessary in order to figure out where you really belong. But yeah it's definitely not easy. I definitely have not figured everything out. It's definitely some days I'm like, I just want to go back to the known, it's so much easier. But yeah, I think it's just getting used to the unknown and getting used to change. Lindsey Dinneen: Yeah. Yeah. And kudos to you for that viewpoint. And I'm sure, I'm sure some days are easier than others. I certainly understand that. But seriously, kudos to you for being willing to adapt to changing circumstances that you didn't plan for and you wouldn't have wished for, but this is really amazing to me as to how you've taken something that is so incredibly difficult and challenging, but you've really embraced the challenge-- and maybe that was a long time in coming-- but you've embraced that challenge and then you're not just helping your own family, which is incredibly important, but you're doing work that's gonna help so many people. And I think that is just amazing. Thank you for doing what you're doing. Zoe Lalji: Absolutely. Like you said, it definitely was a long time of really a lot of self-awareness, a lot of self-work, to get to a place where I was ready to embrace it, like you said, like it's something that has been difficult, has been so trying on our family, so trying on my dad. And a lot of days I am like, why did this happen? And I feel a lot of grief and a lot of sadness and unwillingness to embrace it. But for the most part, I've reached a point where I've realized that this is something that we've come a long way from, and we try to make the best out of the situation and make every day as bright as we can, given everything. And that's all we really can do. And I think watching my dad overcome it himself has been just what has given me the strength I need to get out of that sort of pity, out of that grief of like, why me? Why has this happened? And anger because when you think about what ALS patients go through, it's like you just can't even imagine what it could be like to be in that position. And to watch my dad really take that in stride and be this ferocious warrior through it and keep fighting no matter what life throws at him. He's almost at six years since his diagnosis and he's still fighting and he's still finding a reason to smile every day. And when I think about that it reminds me that it's okay. If he can fight like he's been fighting, then we all have that strength in us and that's, I think, what inspires me to want to help people like him, to want to bring more light into others' lives that are going through what we've gone through. And I think it's our duty really. I think I've gotten a very unique experience to watch somebody rise from the ashes and learn from that and I think that hardship, it sucks, and I'm not gonna say it doesn't at all like it, it does suck. All of it sucks, but it's an opportunity to learn. It's an opportunity to grow and it's an opportunity to become the best version of yourself through it. And there's moments when you don't want to learn , you know, you just, "I'm done with the lessons," like "I've had enough!" I think at the end of the day, it's like everything that I am and everything that I've learned it's valuable, regardless of what I have to go through to get me here. It's who I am. And so I think the best thing I can do with that is use it as a way to empathize with others in a way to really understand what's needed and how to help people that go through similar things that I've seen with my dad. Lindsey Dinneen: Yeah. Yeah. That's absolutely beautiful. Well, I'm wondering is there a particular moment or perhaps series of moments that stands out to you because it clearly confirmed that this was the right career path for you, even though it's been a bit of a meandering one, a pivoting one. Is there any particular moment where you thought, "Okay, this is why I'm here." Zoe Lalji: Like you said, it's a lot of moments. I mean, I would say the first moment was definitely when my dad was diagnosed. But even then I didn't really make that shift of " I'm definitely gonna do this for the rest of my life." It was more of a shock where I realized this is something I really care about. But I think really working on my startup has been so empowering. And then also my internship at Paradromics. I think the main moment that recently has made me realize that kind of clarify what exactly about medicine really drives me is I was invited to speak at a brain computer interface conference at the Chamber of Commerce. And through that I met so many key players in the the ecosystem. And I spoke to a lot of them about what I was passionate about, what I was doing, my story. And it was remarkable to me that so many people really cared and it was so obvious that everyone genuinely cared about the patient and about helping that person. It wasn't about the product, it wasn't about the business. It was about how can we help people the best way that we can and how can we use the potential of this technology to really help people's lives. And I think that energy and being in that space of like people just wanting to help, that was just so new for me because I think when something happens like that, you feel so incredibly alone and nobody could ever really help you, and it's like there's no hope. And people can try to support you and they can try to take care of you, but there's no way that they can actually help. And then even from the medicine side, there really wasn't anything there. And to enter into a room where so many people were making things actively that could help, for me as a daughter of somebody that was going through it, it wasn't so impactful and it made me think what about for others that are like me or for others that are like my dad to be exposed to this world of increasing potential and technology. And I was like, this is where I wanna be. This is home. Lindsey Dinneen: Wow. Yeah. That is a very powerful story. Thank you for sharing that. I have been personally so inspired by people in the medtech industry and healthcare because, you know, you start talking to them and it's easy to see how much they care. It's like you said, it's not just about the product, it's not just about the business, it's not about making money, although everyone needs to to make a living but it's about truly helping people, and I think that's just one of the most inspiring things that I have personally gotten to witness by meeting truly remarkable people through this field. That makes sense to me that, that was a moment that stood out for you. Well, that's amazing. Well, I'm curious, so you're in a really interesting new phase. Yeah. And I, I'm curious as you continue to develop your startup and whatnot, how would you define leadership? Or what does leadership mean to you? Zoe Lalji: I think for me, and from my experience with it, leadership is really about empathy and understanding your team. And the analogy I would use is like a wolf pack. The leader of the wolf pack is always walking behind the pack and making sure nobody gets lost and making sure everybody has purpose and a destination. And I think that as a leader, it's your responsibility to make sure that the team is whole, in a way, where everybody on the team-- you understand them enough to know their strengths and to know their tendencies and set them up to succeed and set them up to benefit the full team and have everybody on the team feel like their strengths are building the team into the best version of itself. And I think having that ability to really understand people really qualifies someone as a great leader. And I, I would liken a leader to a mentor in a way, because it's not about you, if you're leading a team, your success is the team's success, right? And your goal is to inspire success in each of the individual people on the team so that the team can be greater than the sum of its parts. Because everyone's strengths play in a way that they add to each other and compliment each other. And I think from what I've found is that when people realize that you truly understand them and you see what really makes them unique, they're more willing to devote those strengths to whatever cause you're going for. And they're more attentive to the goals you place for the team, the end goal. And I think another thing that a leader really has to do is understand the why of the team and really show that or really demonstrate that to the team and align them under the same why. Because I think what makes a team really unique is their ability to align themselves under that goal and all fight for that goal together. I think those are two things that I find are really important in a leader. Lindsey Dinneen: Yeah, absolutely. Agreed. Yeah. So pivoting a little bit, just for some fun. Imagine someone were to offer you a million dollars to teach a masterclass on anything you want. It can be in your industry or something you're working on now, but doesn't necessarily have to be, what would you choose to teach and why? Zoe Lalji: Wow. That is a fun question. Wow. Okay. I think I would probably want to teach a class on self-awareness through hardship. I think that is one of the biggest things that I have struggled with especially when I think in my gap year was the biggest moment where I realized, I am really defining myself as a caregiver. I'm defining myself as someone that cares for others because I did that every day. And it was so difficult to have my own identity, to have my own sense of self, and I think that really finding that balance of what do I need to be the best version of myself and to do the best for others because of that. I think that journey for me of really finding what's important to me, reprioritizing, because I think moments like these shift your priorities so much. They shift your view of the world. They shift who you are. And to catch up with that is there's so much change going on in your life to keep a pulse on you and who you are, what you stand for, is so incredibly difficult. And I think if you're not careful and you're not placing importance on that, you become misaligned and you don't live in your true values. You don't live within your true values because you don't have that alignment within yourself. And I think, once you've gone through a phase where you've completely lost sight of that and it's a phenomena with caregivers that we tend to forget about ourselves completely. And we place focus on others, on the people we're caring for. And I think in my gap year with both of my parents needing me to be there for them, it made me feel like this is more important, right? Because before the diagnosis with my dad, my highest priority was always family. And caring for others and giving back was such a huge thing that had been instilled in me, and it's still a huge priority for me. But I never had to take care of myself. I never had to place importance on that because there was never a point where I was gasping for air and gasping for care. And I think it also just felt like I didn't know who I was anymore, and that's such a terrible place to be in. And that's why I can say that for, for patients that undergo this, it's that to a totally different extent, and that goes back to my VR project. But I've done so much, coming into college and really getting the space to put myself in different scenarios and see who I am.  I think that sitting with myself and taking that time and doing that work has really allowed me to be there better for my parents, be there better for my family, because I'm just more aligned. I'm more me. And being around my dad when I'm not even me is not helping him. He wants to spend time with me. I think when you neglect yourself, it's hard to be you, you know, it's hard to explain, but I think just having that alignment through something so pivotal in your life, something so earth shattering that happens to you, that kind of shifts who you are. And keeping track of that shift and keeping yourself in your care and treating yourself as a child, because you are. You have to nurture your inner child and really take care of that child and not think that child is perfect because they're not. And the thing about this particular class would be that I haven't figured it out. But I have done a lot of work and I would want to help people that are trying to navigate that because I feel like there's been a lot of trial and error and if I can help people in any way with my experience with it and what's worked for me, and how I went about figuring out what works for me, I think finding that balance within such a all-consuming situation and hardship, that I would wanna help people through that. That's been monumental for me in realizing that myself was important, in defining myself and being aware of myself and who I was. And so yeah, I think realizing that was important through all of this hardship. I think that's one of the biggest learning moments for me, and I'd really wanna share that. Lindsey Dinneen: Yeah. Yeah, absolutely. And like you said, there are so many people who are going through similar things that could really benefit from that. So that would be an amazing masterclass. So I'll look forward to that whenever that comes up. What is one thing you wish to be remembered for after you leave this world? Zoe Lalji: Honestly, I feel like my impact will be in the lives that I've impacted, and if I can be remembered as a friend, as an advocate, and as a mentor for those people, I would be fulfilled. I feel like I would just want to at least help one life that needs that guidance, you know, that feels so alone and feels so hopeless, to bring that small amount of hope, even if nothing at all. And I think where my fulfillment comes is that I want to help people like my dad, people like me, people that have been struggling, that can't find what way is up, which way is the light, either guide them or provide them with some semblance of hope. Or just be a friend, or just be support. Because coming from someone that's been there, coming from someone that can empathize and make them feel like, "Hey, you're not alone. It might feel lonely and it might suck, but you're not alone." Lindsey Dinneen: Yeah. Yes. Absolutely. That is very powerful. Final question, what is one thing that makes you smile every time you see or think about it? Zoe Lalji: Well, I think that one is easy because it's my dad. He's my inspiration. He has so much light within him that only comes from overcoming something like this. And his energy is just so incredible, and he is the reason I keep doing what I do. And I think also, the memories I have of him, the memories of him as my father when I was a kid and things that he used to do with me and things that just really showed that he loved me so much. And those memories that are just so sacred to me and every time I think about it, it's bittersweet, but it always makes me happy to remember what he means to me. Lindsey Dinneen: Yeah, absolutely. Well, Zoe, oh my gosh, you are so very inspirational. I would not wish the path that you have taken on you in the way that it has happened, but I just admire you so much for taking a very hard path, but making so much good come from it and embracing the light and embracing choosing to help others see that light and see hope in a difficult time. Gosh, I cannot wait to continue following your work and seeing what you do because I know you're gonna be impacting a lot of lives. Oh my gosh. Zoe Lalji: Thank you. Yeah, and I really loved being on your podcast. I loved talking to you. This form is amazing and I can't wait to see what other amazing speakers you get on here. Lindsey Dinneen: Awesome. Well, thank you, and we are so honored to be making a donation on your behalf as a thank you for your time today to your family's organization, which is ALS Heroes. This organization honors the heroes amongst us who have stared devastation in the face, only to say, "you do not define me." The organization hopes to guide those heroes in navigating their resources and provide them with hope in the midst of a seemingly hopeless disease. And I'm so excited to continue to learn more about the organization and how we can get involved. So thank you for bringing our attention to it, and thank you again for being here. We wish you continued success as you work to change lives for a better world. Zoe Lalji: Thank you so much, Lindsey. It's been a pleasure. Lindsey Dinneen: Absolutely, and thank you also to our listeners for tuning in. If you're feeling as inspired as I am right now, I would love it if you would share this episode with a colleague or two, continue to pass along the word, and we will catch you next time.  The Leading Difference podcast is brought to you by Velentium. Velentium is a contract design and manufacturing firm specializing in the development, production and post-market support of diagnostic and therapeutic active medical devices, including implantables and wearables for neuromodulation and other class three indications. Velentium's core competencies include electrical design, mechanical design, embedded software, mobile apps, contract manufacturing, embedded cybersecurity, OT cybersecurity, systems engineering, human factors and usability, and automated test systems. Velentium works with clients worldwide from startups seeking seed funding to established Fortune 100 companies. Visit velentium.com to explore your next step in medical device development.

In this deeply personal documentary EAT YOUR CATFISH we meet the matriarch of the Arjomand family, Kathryn, now dependent on round-the-clock care, due to a harrowing diagnosis. She clings to a mordant wit while yearning to witness her daughter's wedding. Co-directors and producers Adam Isenberg, Senem Tüzen and Noah Amir Arjomand — who is Kathryn's son — deliver a brutally frank and darkly humorous portrait of a family teetering on the brink, grappling with the daily demands of disability and in-home caregiving. With her daughter Minou's wedding day approaching, Kathryn is determined to live to see her child get married. Years with Amyotrophic Lateral Sclerosis (ALS) aka Lou Gehrig's Disease, have left Kathryn paralyzed and needing 24-hour care. She relies on an eye-tracking, speech-generating computer to impart her wishes, but it can be an uphill struggle to be ‘heard'. With her mind intact and having opted for mechanical breathing, she could live like this indefinitely. EAT YOUR CATFISH is draws on 930 hours of footage – all filmed without any crew present from a fixed camera and narrated by Kathryn. The result is a profoundly intimate, layered and wryly funny portrait of a family at its breaking point. Co-directors Noah Amir Arjomand & Adam Isenberg (Senem Tüzen) joins us to talk about the ways this film project came about, why they adopted the POV approach to telling the story and how seeing the world from the point-of-view Kathryn could positively impact other family's dealing with a loved one in a comparable medical condition. For more go to: eatyourcatfish.com For more on the POV screening: pbs.org/pov/eatyourcatfish

Six years ago when former Obama staffer Brian Wallach was diagnosed with Amyotrophic Lateral Sclerosis - ALS - a rare neurological disease that kills most people who contract it within a few years, he and his wife Sandra Abrevaya quickly got to work. They launched a non-profit advocacy group I am ALS and a battle to try and fight for increased funding and research that they hoped would lead to a cure for the disease.Since then Wallach and Abrevaya have changed the face of medical advocacy in the country, helping secure legislation that President Biden signed in 2021 that funds $100 million worth of ALS initiatives each year. NPR's Juana Summers spent time with Wallach and Abrevaya to hear about their fight for a cure for ALS.In participating regions, you'll also hear a local news segment to help you make sense of what's going on in your community.Email us at considerthis@npr.org.

What if you could help revolutionize how we care for people with Amyotrophic Lateral Sclerosis (ALS)? Mohammad Sahal, with his unique blend of computer science and neuroscience expertise, is doing just that! Join us for the third episode of the BCI Award Neurocareers podcast series as we take a deep dive to learn how the non-invasive, low-cost, portable neuroergonomic BCI system is transforming the way we care for ALS patients. Discover how custom augmented reality displays are helping patients improve their quality of life from the comfort of their own homes and how this technology is breaking down barriers and revolutionizing healthcare! Join us as we continue exploring the fascinating world of neurotech and focus on the project "A Neuroergonomic BCI with Custom Augmented Reality Display Targeting Continuous At-home Use for People Living with ALS," developed by Sahal and his team, which was nominated for the International Annual BCI Award 2021. Sahal also shares his advice for early career development in the neurotech field and suggests how to submit a successful BCI Award project. This podcast is brought to you through the partnership between Dr. Christoph Guger at g.tec medical engineering GmbH and Neurocareers podcast host Milena Korostenskaja, PhD at The Institute of Neuroapproaches. So why wait? Listen now and be a part of the neurotech revolution that is transforming lives! Join the revolution by submitting your project for BCI award: https://www.bci-award.com/Home About the Podcast Guest: Mohammad Sahal is a tech wizard with a heart for healthcare! With a degree in computer science and minors in neuroscience and mathematics, Mohammad is a triple threat when it comes to developing innovative solutions that merge the worlds of technology and healthcare. He works at Microsoft on the Azure Networking team, focusing on the Web Access Firewall and Content Delivery Network services. But Mohammad's true passion lies in using his expertise to positively impact people's lives. During his time at Drexel University, he led efforts to develop Brain-Computer Interface (BCI) systems for individuals with ALS and other motor neuron diseases (MNDs) - talk about using your skills for good! The project aimed to create a non-invasive, low-cost, portable system that could be used in the comfort of the patients' homes. Mohammad's innovative project has gained recognition in the neurotech community, with his team's project even being nominated for the International Annual BCI Award 2021. With a passion for innovation and a heart for helping others, Mohammad quickly becomes a rising star in the neurotech field. So if you're looking for a tech wizard with a heart of gold, look no further than Mohammad Sahal! Connect with Mohammad Sahal on LinkedIn: https://www.linkedin.com/in/mohammad-sahal/ About the Podcast Host: The Neurocareers podcast is brought to you by The Institute of Neuroapproaches (https://www.neuroapproaches.org/) and its founder, Milena Korostenskaja, Ph.D. (Dr. K), a neuroscience educator, research consultant, and career coach for students and recent graduates in neuroscience and neurotechnologies. As a professional coach with a background in the field, Dr. K understands the unique challenges and opportunities facing students in this field and can provide personalized coaching and support to help you succeed. Here's what you'll get with one-on-one coaching sessions from Dr. K: Identification and pursuit of career goals Guidance on job search strategies, resume and cover letter development, and interview preparation Access to a network of professionals in the field of neuroscience and neurotechnologies Ongoing support and guidance to help you stay on track and achieve your goals You can always schedule a free neurocareer consultation/coaching session with Dr. K at https://neuroapproaches.as.me/free-neurocareer-consultation Subscribe to our Nerocareers Newsletter to stay on top of all our cool neurocareers news at updates https://www.neuroapproaches.org/neurocareers-news    

Laynie Dratch of Penn Medicine comes onto the podcast to answer all of our burning questions about working with a genetic counselor. We loved chatting with her so much that we may need to follow up with a part 2! Let us know what other questions you have for Laynie on our episode art on instagram @remembermepodcast. A list of resources mentioned in this episode are all linked here on our blog. Laynie Dratch, ScM, CGC is a genetic counselor in adult neurology at the University of Pennsylvania in Philadelphia, PA, specializing in Frontotemporal Degeneration (FTD) spectrum disorders.  She helps families with adult-onset conditions such as FTD, Amyotrophic Lateral Sclerosis (ALS), Alzheimer's Disease (AD), and others, navigate genetic testing options and cope with their diagnoses through research and clinical encounters. Her research interests include the lived experiences of individuals with or at risk of developing FTD, issues in predictive genetic testing, and genetic counseling access and service delivery. She is a co-founder of the annual Penn Familial FTD/ALS Conference, as well as the co-founder and chair of the ALS/FTD Working Group within the National Society of Genetic Counselors. Laynie graduated summa cum laude from Colgate University with a BA in neuroscience and a minor in psychology. She completed her master's in genetic counseling at the Johns Hopkins University and the National Institutes of Health. --- Thank you to our sponsor of this episode and Season 7, ⁠⁠LearnFTD⁠⁠. LearnFTD is working to raise awareness of gene mutations in FTD and the importance of genetic testing. Visit ⁠⁠LearnFTD.com⁠⁠ for information and resources on FTD, genetics, and a video providing an overview of genetic testing and counseling. You can also follow LearnFTD on ⁠⁠Facebook⁠⁠ and ⁠⁠Instagram⁠⁠ @LearnFTD. --- ⁠⁠Remember Me⁠⁠ is a podcast created by two moms who became fast friends on Instagram while caregiving for their parents. It features stories of Frontotemporal Dementia - FTD - with a focus on remembering individuals for who they were before the disease. The stories shared are raw, real, and so full of love. We hope it inspires you to "accept the good." "Always, always, accept the good." --- Support this podcast: https://podcasters.spotify.com/pod/show/rememberme/support

Motor Neuron Deficits: Lesions leading to lost function! Join Hand to Shoulder with Cassie and Shelly as we dissemble motor neurons and variations of symptoms, which in turn, lead to ALS. This very energetic podcast with Cynthia Ivy out of Phoenix, AZ, will open your mind to neurological deficits and the role of a hand therapist with someone who presents with hand or upper limb weakness. We hope you gather several takeaways from this complex topic. Cindy Ivy OTD, M.Ed., CHT began working as adjunct faculty at NAU, Phoenix Biomedical Campus in 2014 and joined the faculty in August of 2015 as Associate Clinical Professor and Residency coordinator. She is studying the effects of carpometacarpal stabilization exercises on pain from osteoarthritis of the first carpometacarpal joint. Her research interests also include studying functional outcomes of the use of finger orthoses versus injection for stenosing tenosynovitis (trigger finger) and studying quality of life and positive effects on function and independence in persons with Amyotrophic Lateral Sclerosis (ALS). In addition to ALS, She is also studying interventions to improve independence in people with Parkinson's Disease. Dr. Ivy carries a bachelor's degree in occupational therapy from the University of Wisconsin, Madison and a Master's of Education in Counseling Psychology from Northern Arizona University. Her post professional clinical doctorate in occupational therapy, Hand therapy emphasis is from Rocky Mountain University of Health Professions. Cindy Ivy has a passion for teaching and has taught in many capacities over the past 30 years while working as a hand therapist and occupational therapist Susan M Smith, C. C. (2015). Upper Extremity orthoses use in amyotrophic lateral sclerosis/motor neuron disease: A systematic review. International Journal of Physical Medicine and Rehabilitation, 03(02). https://doi.org/10.4172/2329-9096.1000264 Ivy, C. C., Smith, S. M., & Materi, M. M. (2014). Upper Extremity orthoses use in amyotrophic lateral sclerosis/motor neuron disease: Three case reports. HAND, 9(4), 543–550. https://doi.org/10.1007/s11552-014-9626-x

Partner Chicago Regional Office Veteran Benefits Administration Panelists:Monica Arango  - Chicago Regional Office Veteran Benefits Administration Subject Matter Expert and POW Coordinator Exam Liason.Molly Sikora  - Chicago Regional Office Veteran Benefits Administration Management Analyst and Director's Staff.Roberto  Salazar  - Chicago Regional Office Veteran Benefits Administration Records and Information Management Specialist, Support Services Division, and US Marine Corps Iraq Combat Veteran 

Fran Finney, wife of bitcoin legend Hal Finney joins us to talk about Hal's Life, her work with Asher Garfinkel in fighting ALS with the "Running Bitcoin Challenge". Fran and Asher go in-depth on what Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease is, how bitcoin has changed their lives and more. We also cover the bitcoin news at the beginning of the show and talk about the mining incentives with a fixed supply unit such as Bitcoin. Guest Information: Fran Finney: https://twitter.com/franfinney Asher Garfinkel: https://twitter.com/alsagoldenwest Connect with Alex: Alex Stanczyk Twitter: https://twitter.com/alexstanczyk Sign up for Swan Private today: https://www.swanbitcoin.com/private/ "Buy, Learn and Earn" with the Swan Bitcoin Mobile App: https://www.swanbitcoin.com/app/ Hello and welcome to The Café Bitcoin Podcast brought to you by Swan Bitcoin, the best way to buy and learn about Bitcoin. We're excited to announce we are bringing the The Café Bitcoin conversation from Twitter Spaces to you on this show, The Café Bitcoin Podcast, Monday - Friday every week. Join us as we speak to guest like Max Keiser, Lyn Alden, Tomer Strolight, Cory Klippsten and many others from the bitcoin space. Also, be sure to hit that subscribe button to make sure you get the notifications when we launch an episode. Join us Monday - Friday 7pst/10est every Morning and become apart of the conversation! Thank you again and we look forward to giving you the best bitcoin content daily here on The Café Bitcoin Podcast. Swan Bitcoin is the best way to accumulate Bitcoin with automatic recurring buys and instant buys from $10 to $10 million. Get started in just 5 minutes. Your first $10 purchase is on us: https://swanbitcoin.com/yt Connect with Swan on social media: Twitter: https://twitter.com/SwanBitcoin

Join us for a special episode on the innovative efforts to help those living with Amyotrophic Lateral Sclerosis (ALS). Israeli neurotech scientists and educators have organized a national program using brain-computer interfaces (BCIs) to improve the lives of those with ALS. In this educational program, students learn about BCIs and use their knowledge to create personalized devices for patients to address their individual needs. Tune in to learn more about this unique program from its leader Asaf Harel and appreciate the hope it brings to those living with ALS! About the podcast guest: Asaf Harel focuses on designing and developing brain-computer interfaces for human sensory and motor systems, data analysis, signal processing, machine learning, and multi-site experimental coordination. Asaf believes that "in the near future, our interactions with the digital world will be mediated by our attention and intention, augmenting current touch, gesture, and speech inputs." Asaf is the co-founder and leader of BrainstormIL, an organization dedicated to establishing Israel as a neurotech leader. With a community of over 3000 members across eight chapters at top academic institutions in Israel, BrainstormIL hosts national events, competitions, courses, conferences, and connections to stakeholders in the Israeli neurotech ecosystem. Useful links: www.brainstormil.com - Israel's Neurotechnology Community (Non-Profit Organization) www.neurotechx.com - A wonderful global community advancing and connecting the neurotech community www.brainstormil.com/bci-4-als - The site for the BCI4ALS program www.linkedin.com/in/asaf-harel/ - Asaf's LinkedIn page   About the podcast host: The Neurocareers podcast is brought to you by The Institute of Neuroapproaches ( https://www.neuroapproaches.org/ ) and its founder - Milena Korostenskaja, Ph.D. (Dr. K) - a neuroscience educator, neuroscience research consultant, and career coach for students and recent graduates in neuroscience and neurotechnologies. As a professional coach with a background in the field, Dr. K understands the unique challenges and opportunities facing students in this field. Whether you're looking to apply for jobs, build your professional network, or develop your research skills, Dr. K can provide personalized coaching and support to help you succeed. What you'll get: One-on-one coaching sessions to help you identify and pursue your career goals; Tailored guidance on job search strategies, resume and cover letter development, and interview preparation; Access to a network of professionals in the field of neuroscience and neurotechnologies; Ongoing support and guidance to help you stay on track and achieve your goals. You can always schedule a free neurocareer consultation/coaching session with Dr. K at: https://neuroapproaches.as.me/free-neurocareer-consultation Also, find your support in the Your Support Station podcast with Dr. K here: https://www.neuroapproaches.org/podcast-2  

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.11.519991v1?rss=1 Authors: Narayanan, R., Panwar, A., Butler, T. J., Cutrupi, A. N., Kennerson, M., Vucic, S., Balasubramaniem, A., Mangelsdorf, M., Wallace, R. H. Abstract: Mutations in TDP-43 are known to cause Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). TDP-43 binds to and regulates splicing of several RNA including Zmynd11. Zmynd11 is a transcriptional repressor and a potential E3 ubiquitin ligase family member, known for its role in neuron and muscle differentiation. Mutations in Zmynd11 have been associated with autism with significant developmental motor delays, intellectual disability, and ataxia. Here, we show that Zmynd11 is aberrantly spliced in the brain and spinal cord of transgenic mice overexpressing a mutant human TDP-43 (A315T), and that these changes occur before the onset of motor symptoms. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.05.519172v1?rss=1 Authors: Byrd, A. T., Marmorale, L., Addison, V., Marcinowski, S., Buchan, J. R. Abstract: A key pathological hallmark in greater than 97% of all Amyotrophic Lateral Sclerosis (ALS) cases is the cytoplasmic mislocalization and aggregation of a nuclear RNA binding protein, TDP-43. Driving clearance of cytoplasmic TDP-43 reduces toxicity in various ALS models, though how TDP-43 clearance is regulated remains controversial. To address this, we conducted an unbiased yeast genome-wide screen using high-throughput dot blots to identify genes that affect TDP-43 levels. Our screen identified ESCRT complex factors, which induce membrane invagination (particularly at multi-vesicular bodies; MVBs) and K63-linked ubiquitination as key facilitators of TDP-43 endolysosomal clearance. TDP-43 co-localized and bound Rsp5/NEDD4 and ESCRT proteins, and perturbations to either increased TDP-43 aggregation and accumulation. NEDD4 also ubiquitinates TDP-43. Lastly, TDP-43 accumulation caused formation of "giant" MVBs which could reflect a pathological consequence of TDP-43 pertinent to ALS. Our studies shed light on endolysosomal-mediated cytoplasmic protein degradation, which likely impacts multiple substrates, and may be a target for novel ALS therapeutic strategies. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Amyotrophic lateral sclerosis (ALS) – also known as Lou Gehrig's disease – is a rapidly progressive, neurodegenerative disease.1 Those living with ALS eventually lose their ability to walk, dress, write, speak, swallow and eat.1 ALS can affect people of all races and ethnic backgrounds, but did you know that Veterans are twice as likely to develop ALS than those who haven't served in the military? This Veterans Day, we honor those who have served in the U.S. armed forces and thank them for the sacrifices they've made to protect our country. I had the extreme honor of speaking with Juan Reyes, a U.S. Air Force Veteran living with ALS and a MTPA Patient Ambassador, to share his story of living with ALS, discuss how he's helping to spread awareness of this devastating disease among Veterans, and how others living with the disease can help support the ALS community. Along with his wife of 33 years, Meg.

Find a Place for Me: Embracing Love and Life in the Face of Death (Pact Press, November 1, 2022) is an award-winning memoir about facing a marriage's last act—a spouse's death—as a couple united in mind and holding hands. Author Deirdre Fagan, D.A., was married eleven years and had two young children when her forty-three-year-old husband Bob was diagnosed with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. ALS determined the journey their marriage would now take, but Bob and Deirdre were resolute in how they traversed their remaining months as a couple. Chronicling Bob's illness, Find a Place for Me is also the love story of a happy marriage filled with humor, honesty, and essential conversations, despite their tragic circumstances. In this moving and surprisingly funny book, Deirdre and Bob raise a glass to love and the life each of them has left while learning how to lovingly say goodbye.Find a Place for Me received a bronze medal in the 2022 Living Now Book Awards. An offshoot of the IPPY awards, one of the top awards given to independent publishers, the Living Now Book Award is given to books based on their outstanding ability to enrich readers' lives. Deirdre visits with Mark Alyn.

Find a Place for Me: Embracing Love and Life in the Face of Death (Pact Press, November 1, 2022) is an award-winning memoir about facing a marriage's last act—a spouse's death—as a couple united in mind and holding hands. Author Deirdre Fagan, D.A., was married eleven years and had two young children when her forty-three-year-old husband Bob was diagnosed with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. ALS determined the journey their marriage would now take, but Bob and Deirdre were resolute in how they traversed their remaining months as a couple. Chronicling Bob's illness, Find a Place for Me is also the love story of a happy marriage filled with humor, honesty, and essential conversations, despite their tragic circumstances. In this moving and surprisingly funny book, Deirdre and Bob raise a glass to love and the life each of them has left while learning how to lovingly say goodbye.Find a Place for Me received a bronze medal in the 2022 Living Now Book Awards. An offshoot of the IPPY awards, one of the top awards given to independent publishers, the Living Now Book Award is given to books based on their outstanding ability to enrich readers' lives. Deirdre visits with Mark Alyn.

Days before their 25th wedding anniversary, Lisa Valentine Clark lost her husband Christopher to Amyotrophic Lateral Sclerosis (ALS) after a four-year battle. While both Lisa and Clark had been big figures in the performing circle in their area, they were astonished and humbled by the support they got from the community, friends, family, and even strangers. While Chris slowly lost control of his body, his spirits remained high as he choose to keep ‘Living ‘til the end.” Together, their family leaned on faith, and just as they had heard time and time again in their improv classes, accepted the challenges thrown at them with a “Yes, and…” attitude. Lisa joins this episode of the Relentlessly Resilient podcast to share their story.  Even though we live in challenging times we can become Relentlessly Resilient as we lean on and learn from one another's experiences. Hosts Jennie Taylor and Michelle Scharf are no strangers to overcoming adversity; Michelle lost her husband to cancer, while Jennie's husband Major Brent Taylor was killed in the service of our country. Their stories bond them together and now listeners can join them weekly as they visit with others enduring challenges and who teach us how they are exercising resiliency, finding value in their grief, and purpose in moving forward.  Listen to the Relentlessly Resilient Podcast regularly on your favorite platform, at kslpodcasts.com, kslnewsradio.com, or on the KSL App. Join the Resilience conversation on Facebook at @RelentlesslyResilient and Instagram @RelentlesslyResilientPodcast. Produced by KellieAnn Halvorsen.See omnystudio.com/listener for privacy information.

This season (season 4) we are taking a deep dive into Degenerative Myelopathy which  is a common, merciless neurological disorder in senior German Shepherds that surfaces anywhere between 7 and 14 years of age and is seen more in males than females. It is a slow, progressive spinal cord disorder similar to Amyotrophic Lateral Sclerosis (ALS) in humans, which starts with a loss of balance and coordination that progresses to muscle weakness. Then, in time the dog will be unable to support himself, which will lead to paralysis resulting in quadriplegia or paraplegia. Eventually, death occurs from respiratory failure due to paralysis of muscles around the chest cavity.  There is no cure for Degenerative Myelopathy, but supportive care and Physical Therapy may slow down the progression of the disease. In this podcast, we'll share our experiences with DM and bring on guests who specialize in DM, mobility devices, and pain/anxiety relief experts. Our goal for this season of the #Lifewitholddogs podcast is to  arm you with as much DM knowledge as possible should your senior German Shepherd be stricken get it.DM blog post link:https://www.wpsgss.org/post/degenerative-myelopathy-dm-an-all-too-common-merciless-disease-in-senior-german-shepherdsWoody's Place Senior German Shepherd support group:https://www.facebook.com/groups/search/groups_home/?q=wpsgss%20degenerative%20myelopathy%20support%20groupYou can find Woody's Place Senior German Shepherd Sanctuary online at:www.wpsgss.orghttps://www.facebook.com/woodysplacesgsshttps://www.instagram.com/wpsgss/https://www.youtube.com/channel/UC7Tb1hKnOWEamQstkqAxEygWe would LOVE it if you could leave a thumbs up or comment! Please and Thank you!You can support our podcast by going to: (http://www.patreon.com/LifeWithOldDogs)Support the show

How much joy and encouragement would you have to give if you knew your time was short? My guest today is Tina. She is a long-time friend and was recently diagnosed with Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive neuromuscular disease. ALS is characterized by progressive degeneration of motor nerve cells in the brain (upper motor neurons) and spinal cord (lower motor neurons). After going through an 18-month process Tina was given the news she has ALS and that it would one day take her life. Tina has made it her mission with the time, she has left to be a source of joy and encouragement. Join me as I try on Tina's very comfy slippers. •Please visit https://www.worldlovebank.com/ to learn more about WORLDLOVEBANK. LOVE after all is the most valuable asset, and WORLDLOVEBANK  will help you build emotional security. As we all know life is temporary... accidents happen. Keep your I love you's safe. •Remember when you walk in Other People's Shoes you get a different perspective!•Other People's Shoes would love your financial gift to help support the show click here•Have questions or want to give feedback call or text: 203-548-SHOE•If you enjoy the show consider subscribing on your favorite podcast platforms, so you don't miss an episode. We would also love it if you could leave us a review click here!•To hear other episodes go to:www.opspodcast.com•Social Media:**Facebook: Instagram: Twitter: ** @opspodcashow

In this podcast, we are joined by Indu Navar. Indu Navar is the CEO of Everything ALS, a company that prioritizes bringing awareness to Amyotrophic Lateral Sclerosis (ALS) and those who suffer from it. ALS is a neurological condition that affects the victim's motor neurons. This causes muscle atrophy all across the body, which can eventually cause suffocation and even death.    Listen now to learn about: The importance of diagnosing neurodegenerative diseases early. What happens to victims of ALS. What the typical onset age for ALS is. How ALS progresses in victims.  We don't know much about ALS and how to treat it. Indu Navar is dedicated to facilitating more investigation into this condition so that doctors can more effectively treat it. This episode explores how advocacy and citizen research plays an important role in solving ALS and conditions like it. To learn more about Indu Navar and her work at Everything ALS, visit www.everythingals.org. Episode also available on Apple Podcast: http://apple.co/30PvU9C

Three months ago we did a podcast with Randy Curits about his recent diagnosis of ALS in March and what it was like for someone who studies and cares for people living with serious illness, to now be someone who is living with serious illness.  It was one of our favorite podcasts we've done, but also got us to think “wait, how come we've never done a podcast on ALS?” We fix that on today's podcast.  We've invited Elizabeth Lindenberger and Kara Bischoff to talk about what every geriatrician and palliative care clinician should know about ALS.    Topics include: prognosis in ALS, disease modifying therapies (and when/if to discontinue, advance care planning in ALS, the role of embedding geriatrics/palliative care in ALS clinics, interventions in ALS (noninvasive ventilation, PEG tubes, and trachs), and symptom management as the disease progress.  So take a listen and if you want to take a deeper dive, take a look at these articles: Embedded Palliative Care for Amyotrophic Lateral Sclerosis: A Pilot Program and Lessons Learned Top Ten Tips Palliative Care Clinicians Should Know About Amyotrophic Lateral Sclerosis  

In this episode, we review the high-yield topic of Amyotrophic Lateral Sclerosis (ALS) from the Neurology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets

Degenerative Myelopathy (DM) is a common, merciless neurological disorder in senior German Shepherds that surfaces anywhere between 7 and 14 years of age, and is seen more in males than females. It is a slow, progressive spinal cord disorder that is similar to Amyotrophic Lateral Sclerosis (ALS) in humans.In this #Lifewitholddogs podcast episode, we share our experiences with DM, products we use for supportive care, physical therapies that help keep our seniors with DM comfortable, and share the mistakes I (Dawn) made with Woody, my very first DM dog.Our correlating blog post this week has lots of imagery about DM and links for helpful supportive care products, so be sure to visit to get that additional information.https://www.wpsgss.org/post/degenerative-myelopathy-dm-an-all-too-common-merciless-disease-in-senior-german-shepherdsWe also have a Degenerative Myelopathy support group on Facebook where we share information about DM and you can post as well! It's free to join.https://www.facebook.com/groups/2009914109023556You can find Woody's Place Senior German Shepherd Sanctuary online at:www.wpsgss.orghttps://www.facebook.com/woodysplacesgsshttps://www.instagram.com/wpsgss/https://www.youtube.com/channel/UC7Tb1hKnOWEamQstkqAxEygSupport the show (http://www.patreon.com/#LifeWithOldDogs)

When teacher and performer David Martin found out that his friend and music director Chris Clark was diagnosed with Amyotrophic Lateral Sclerosis (ALS) in early 2016, he was devastated. But Chris’s pervasively optimistic outlook on tackling the terminal diagnosis changed David’s own life outlook. David launched a performance program to educate the public and raise awareness of ALS while celebrating the lives of its victims, which included Chris in 2020. “BeatALS Benefit” concerts and programs help unite schools, communities, and businesses in a concentrated effort to beat ALS through the songs of The Beatles. With upcoming concerts in October 2021, Dave joins the Relentlessly Resilient podcast to discuss the BeatALS programs, invite listeners to donate or participate in the concerts, and share the stories of resilience he has learned from ALS patients who “Take a Sad Song and Make it Better.” Even though we live in challenging times we can become Relentlessly Resilient as we lean on and learn from one another’s experiences. Hosts Jennie Taylor and Michelle Scharf are no strangers to overcoming adversity; Michelle lost her husband to cancer, while Jennie’s husband Major Brent Taylor was killed in the service of our country. Their stories bond them together and now listeners can join them weekly as they visit with others enduring challenges and who teach us how they are exercising resiliency, finding value in their grief, and purpose in moving forward. Listen to the Relentlessly Resilient Podcast regularly on your favorite platform, at kslpodcasts.com, kslnewsradio.com, or on the KSL App. Join the Resiliences conversation on Facebook at @RelentlesslyResilient and Instagram @RelentlesslyResilientPodcast. Produced by KellieAnn Halvorsen.See omnystudio.com/listener for privacy information.

Humbling conversation with, Eric Roy. Eric was recently diagnosed with Amyotrophic Lateral Sclerosis (ALS), a disease that is very common in his family. Eric explains what ALS is and goes into detail about how the disease is rapidly attacking his body. Eric talks about some recent medical trials that have showed some promising results, but more research and funding is needed. Eric and his family need your support during these challenging times. The family has started a GoFundMe and the funds collected will assist Eric and his family in purchasing proper medical care, mobility/communication equipment, medications not covered by insurance, and in home nursing support. Please visit Eric's GoFundMe down below. Any donation will be greatly appreciated. Link below. https://www.gofundme.com/f/eric-roy-facing-als?utm_source=customer&utm_medium=sms&utm_campaign=p_cp%20share-sheet&fbclid=IwAR0N68lb2ooB19rlTPOYlAyWuxWk1mmqAoElUdj3M4QG1mXZwiJ1Ggjooxo

With an extensive scientific background in neurodegeneration, and especially in Amyotrophic Lateral Sclerosis (ALS), Kim is driven to move safe and effective therapies to people with ALS or with other rare diseases across the globe. After two postdocs in academia, Kim set out to provide science consultancy to biotech, academia, and patient organizations. In addition, as a career coach, she feels strongly about inspiring and empowering academic scientists to obtain the careers that they want, either within or beyond academia. Kim has worked on a short film about ALS called The First Color: https://www.instagram.com/the_first_color_movie/ Kim is in the midst of setting up an online platform for (academic) career development: http://kimu.info/ More updates about this platform are to follow! Episode music - Funkorama by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3788-funkorama License: http://creativecommons.org/licenses/by/4.0/ *Extra sounds provided by baby Emmanuelle Sophia, sorry for the interference! --- Send in a voice message: https://anchor.fm/macademia/message

Dr. Shelly Hoover is a wife, mother, grandmother, daughter, sister, and friend. She's a veteran, author, educator, and advocate. It's what she does. It's who she is. In 2013, her neurologist told her that she only had two to five years to live. After a year of trying to figure out what was slowly happening to her body, Shelly was diagnosed with Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's disease. Some call it that Ice Bucket Challenge disease. From shellyhoover.com, “whatever you call it, it's a fatal diagnosis with no effective treatment or cure. Yet I have much to live for and I'm determined to live in gratitude and joy regardless of circumstance. I feel alive when while I'm encouraging others to live their best life.” - Tony interviews Shelly about their shared experience running around a middle school track to help motivate kids, and raise money for the school, and how to make the event bigger, and better in the future, only to find that a few short months later, Shelly would begin to recognize the initial symptoms of what would eventually be diagnosed as ALS. - Shelly has also written a book, Timeless Sisters, available on Amazon https://amzn.to/38fiMuJ The book is about three strong women, Janene, Cora, and Amadahy, who live in the same North Carolina town centuries apart. Janene, a modern-day high school teacher, loses her career and identity in the face of a devastating illness. Cora, an enslaved person during the Civil War, flees the Yarbrough plantation after her family is murdered. She finds refuge at Mama Hattie's house only to encounter the killer years later. Amadahy, a Cherokee before the European invasion, loses a child and her husband leaves. She finds an unlikely love while on a river adventure and returns to find trouble at home. A sacred, maternal talisman connects the three women as they search for lasting peace. Follow this fast-paced, emotional journey to the collective sisterhood at the river. The book has received phenomenal reviews from both critics, and readers alike. You can learn more about Shelly at http://shellyhoover.com - Tony's new best selling book "He's a Porn Addict...Now What? An Expert and a Former Addict Answer Your Questions" is now available on Kindle. https://amzn.to/38mauBo - Tony Overbay, is the co-author of "He's a Porn Addict...Now What? An Expert and a Former Addict Answer Your Questions" now available on Amazon https://amzn.to/33fk0U4. The book debuted in the number 1 spot in the Sexual Health Recovery category and remains there as the time of this record. The book has received numerous positive reviews from professionals in the mental health and recovery fields. - The book tackles tough questions with answers from both the expert and the addict's point of view. Tony, a licensed marriage and family therapist, and creator of The Path Back, an online pornography addiction recovery program that has helped hundreds of people overcome turning to pornography and other compulsive sexual behaviors as a coping mechanism, and Joshua Shea, former addict, and author of the book “The Addiction Nobody Will Talk About” read their respective answers to questions such as "Finding out he's addicted to porn has turned me off to sex completely, what should I do?" And "How much do we tell the kids?" And "Does this mean that God is mad at me, or doesn't love me?" - Reviews include: "This is the most helpful book for porn addicts and the people who (still) love them. One of the most courageous and timely books to help with a widespread and almost never talked about epidemic that is ruining marriages, careers, and lives. It will give hope to millions of people who are addicted to pornography. -- Mark Goulston, MD, FAPA, Author of Just Listen Discover the Secret to Getting Through to Absolutely Anyone. - You can learn more about Tony's pornography recovery program The Path Back by visiting http://pathbackrecovery.com And visit http://tonyoverbay.com and sign up to receive updates on upcoming programs, and podcasts. - The Virtual Couch is sponsored by http://Betterhelp.com/virtualcouch Betterhelp.com is the world's leading provider of online therapy. Their mission is to make professional counseling accessible, affordable, and convenient, so anyone who struggles with life's challenges can get help, anytime, anywhere. Head to http://betterhelp.com/virtualcouch for 10% off your first month of services

Dr. Shelly Hoover is a wife, mother, grandmother, daughter, sister, and friend. She's a veteran, author, educator, and advocate. It's what she does. It's who she is. In 2013, her neurologist told her that she only had two to five years to live. After a year of trying to figure out what was slowly happening to her body, Shelly was diagnosed with Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's disease. Some call it that Ice Bucket Challenge disease. From shellyhoover.com, “whatever you call it, it's a fatal diagnosis with no effective treatment or cure. Yet I have much to live for and I'm determined to live in gratitude and joy regardless of circumstance. I feel alive when while I'm encouraging others to live their best life.” - Tony interviews Shelly about their shared experience running around a middle school track to help motivate kids, and raise money for the school, and how to make the event bigger, and better in the future, only to find that a few short months later, Shelly would begin to recognize the initial symptoms of what would eventually be diagnosed as ALS. - Shelly has also written a book, Timeless Sisters, available on Amazon https://amzn.to/38fiMuJ The book is about three strong women, Janene, Cora, and Amadahy, who live in the same North Carolina town centuries apart. Janene, a modern-day high school teacher, loses her career and identity in the face of a devastating illness. Cora, an enslaved person during the Civil War, flees the Yarbrough plantation after her family is murdered. She finds refuge at Mama Hattie's house only to encounter the killer years later. Amadahy, a Cherokee before the European invasion, loses a child and her husband leaves. She finds an unlikely love while on a river adventure and returns to find trouble at home. A sacred, maternal talisman connects the three women as they search for lasting peace. Follow this fast-paced, emotional journey to the collective sisterhood at the river. The book has received phenomenal reviews from both critics, and readers alike. You can learn more about Shelly at http://shellyhoover.com - Tony's new best selling book "He's a Porn Addict...Now What? An Expert and a Former Addict Answer Your Questions" is now available on Kindle. https://amzn.to/38mauBo - Tony Overbay, is the co-author of "He's a Porn Addict...Now What? An Expert and a Former Addict Answer Your Questions" now available on Amazon https://amzn.to/33fk0U4. The book debuted in the number 1 spot in the Sexual Health Recovery category and remains there as the time of this record. The book has received numerous positive reviews from professionals in the mental health and recovery fields. - The book tackles tough questions with answers from both the expert and the addict's point of view. Tony, a licensed marriage and family therapist, and creator of The Path Back, an online pornography addiction recovery program that has helped hundreds of people overcome turning to pornography and other compulsive sexual behaviors as a coping mechanism, and Joshua Shea, former addict, and author of the book “The Addiction Nobody Will Talk About” read their respective answers to questions such as "Finding out he's addicted to porn has turned me off to sex completely, what should I do?" And "How much do we tell the kids?" And "Does this mean that God is mad at me, or doesn't love me?" - Reviews include: "This is the most helpful book for porn addicts and the people who (still) love them. One of the most courageous and timely books to help with a widespread and almost never talked about epidemic that is ruining marriages, careers, and lives. It will give hope to millions of people who are addicted to pornography. -- Mark Goulston, MD, FAPA, Author of Just Listen Discover the Secret to Getting Through to Absolutely Anyone. - You can learn more about Tony's pornography recovery program The Path Back by visiting http://pathbackrecovery.com And visit http://tonyoverbay.com and sign up to receive updates on upcoming programs, and podcasts. - The Virtual Couch is sponsored by http://Betterhelp.com/virtualcouch Betterhelp.com is the world's leading provider of online therapy. Their mission is to make professional counseling accessible, affordable, and convenient, so anyone who struggles with life's challenges can get help, anytime, anywhere. Head to http://betterhelp.com/virtualcouch for 10% off your first month of services

The printmaker and artist Jon Fasanelli-Cawelti has a solo exhibit entitled “Atlas” on display at the Muscatine Art Center. Consisting of over 40 large-scale drawings and prints, the work in this show was created over the past five years despite — and perhaps because of — Jon's diagnosis of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease.

The printmaker and artist Jon Fasanelli-Cawelti has a solo exhibit entitled “Atlas” on display at the Muscatine Art Center. Consisting of over 40 large-scale drawings and prints, the work in this show was created over the past five years despite — and perhaps because of — Jon's diagnosis of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease.

Steve and Caleb are back and in this episode, they are back to discussing science straight out of the gate. Steve has been reading research about Amyotrophic Lateral Sclerosis (ALS) and he talks a bit about that. This leads to a discussion on the balance of perfection and practicality in science. Sometimes it is hard to figure out when enough is enough when designing an experiment. Sometimes the benefit is not worth all of the work it will take. Next, the guys talk about some career options that are available with a biology degree. When Caleb and Steve were undergrads they weren't aware of all of the possible careers in biology. They also talk about presenting science at meetings. Steve is hoping to present his thesis research at an American Physiological Society meeting this year. Caleb also gives some advice on giving an interesting presentation. Finally, they end with some speculation on the role of robots in society. Inevitably, they get on the "will the robots take over the world?" debate and Caleb picks his evil robot apocalypse weapon of choice. This is a fun science filled episode, check it out! Website Facebook Instagram Twitter